Hub : Genes

UGDH

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0790 0.0250 2.5e-05 0.026 0.047 0.062 0.053 0.072 3.2e-04 1.9e-06 4.4e-08 4.8e-07 4.6e-09
2 GTEx Cells Transformed fibroblasts 0.1370 0.0480 3.9e-04 0.029 NA 0.030 NA 0.046 2.7e-03 NA 2.4e-03 NA 2.4e-04
3 METSIM Adipose 0.1191 0.0318 2.8e-11 0.065 0.067 0.065 0.064 0.065 5.2e-10 2.6e-10 5.4e-10 6.5e-10 4.8e-10
4 NTR Blood 0.0454 0.0122 2.2e-09 0.032 0.037 0.031 0.038 0.032 1.0e-10 3.7e-12 2.0e-10 2.7e-12 1.5e-10
5 TCGA Breast Invasive Carcinoma 0.0208 0.0099 4.1e-04 0.022 0.012 0.027 NA 0.027 1.7e-05 1.2e-03 2.9e-06 NA 2.8e-06
6 TCGA Kidney Renal Papillary Cell Carcinoma 0.0590 0.0300 3.4e-03 0.025 0.032 0.023 NA 0.023 1.4e-02 5.9e-03 1.8e-02 NA 1.8e-02
7 TCGA Pheochromocytoma and Paraganglioma 0.1980 0.0770 1.1e-03 0.052 0.073 0.052 NA 0.038 3.9e-03 7.7e-04 4.0e-03 NA 1.2e-02
8 TCGA Soft Tissue Sarcoma 0.1080 0.0470 3.9e-04 -0.002 0.076 0.026 NA 0.026 4.3e-01 2.7e-05 1.1e-02 NA 1.0e-02
9 TCGA Stomach Adenocarcinoma 0.0540 0.0260 7.0e-04 0.016 0.032 0.015 NA 0.013 2.3e-02 2.1e-03 2.8e-02 NA 3.5e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bipolar Disorder (2018) 1.3 2.1 4.3 -1.5 2.1 1.7 1.3 1.6 1.5 1.2 0.4 1.1
Bipolar Disorder or Schizophrenia 1.2 3.0 6.0 -1.4 1.9 2.4 1.1 1.3 2.1 2.4 0.6 1.3
Depressed Affect (Nagel 2018) 1.2 2.5 6.8 0.5 1.5 2.6 0.6 0.8 1.9 -1.4 1.1 2.3
Depression (Nagel 2018) 1.2 1.8 4.0 -0.3 1.0 1.8 1.4 1.0 2.0 -0.6 0.7 2.0
Intelligence (Savage-Jansen 2018) 1.7 5.2 10.5 -2.4 2.2 2.3 2.3 1.8 1.7 -3.2 1.9 2.5
Neuroticism (Nagel 2018) 1.8 4.1 8.3 -0.3 2.2 2.9 1.8 2.0 2.5 -1.1 1.3 2.7
Schizophrenia (2018) 0.7 1.4 4.9 -0.6 0.8 1.8 0.4 0.4 1.5 2.2 0.5 0.7
Schizophrenia vs Biploar Disorder 0.6 0.7 3.2 1.8 -0.5 0.1 -0.7 -1.2 -0.5 0.8 -0.5 -0.1
Worry (Nagel 2018) 1.4 3.0 8.2 -0.5 1.9 2.9 1.7 1.2 2.1 -0.0 1.5 2.0
Alzheimer’s Disease (in mother) 1.0 1.2 2.0 0.5 -1.4 -1.3 -1.3 -1.2 -0.7 0.7 -1.3 -1.2
Alzheimer’s Disease (in father) 0.1 0.1 0.2 -0.3 -0.3 0.5 0.0 0.1 -0.1 -0.1 -0.1 -0.4
Alzheimer’s Disease (including proxy) 1.7 2.4 4.4 0.3 -2.0 -2.1 -1.8 -1.7 -1.5 -0.1 -1.3 -1.8
Crohns Disease (2017) 1.3 2.9 8.3 1.1 -2.2 -0.3 -1.5 -1.6 -1.7 -0.6 -2.9 -1.8
Irritable Bowel Disease (IBD) 1.4 3.3 9.1 0.8 -2.4 -0.7 -1.7 -1.9 -1.7 -0.6 -3.0 -1.8
Ulcerative Colitis (UC) 1.0 1.8 3.7 0.5 -1.7 -0.6 -1.6 -1.5 -1.4 -0.7 -1.9 -1.4
Major Depression (MDD) 0.3 0.3 1.2 0.4 -0.2 0.2 -1.1 -0.8 0.2 -0.0 -0.5 -0.7
Reaction Time 0.4 0.8 1.9 0.6 -1.0 -0.9 -1.1 -1.4 -1.0 -0.1 -0.1 -0.9
Verbal and Numeric Reasoning (VNR) 1.9 4.6 8.1 -2.8 2.3 1.6 2.2 1.8 1.5 -2.6 1.3 2.3
Breast Cancer 0.3 0.7 4.0 -0.0 -0.3 -0.8 0.3 -0.4 0.2 1.0 2.0 -0.2
Ovarian Cancer 0.8 1.1 2.6 -0.7 -0.9 -1.6 -0.7 -0.4 -1.5 -0.3 -1.4 -1.1
Prostate Cancer 0.6 0.8 3.0 -0.4 1.0 1.0 1.2 1.7 0.4 -0.5 0.1 0.8
Age at First Birth 0.7 1.0 5.1 -2.3 0.7 -0.6 1.0 0.5 -0.0 -1.1 0.1 0.2
Bipolar Disorder (2011) 0.8 0.7 2.9 -1.7 1.4 0.8 1.1 0.0 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 0.1 0.1 0.3 0.2 0.5 0.1 0.0 -0.4 0.1 -0.2 0.6 0.6
Coronary Artery Disease (CAD) 0.4 0.4 1.5 0.7 -0.7 -0.2 -0.7 0.1 -0.6 -0.4 -1.2 -0.5
Crohns Disease (2012) 2.1 3.4 12.3 1.3 -1.4 -0.8 -2.1 -1.3 -2.1 -1.0 -3.5 -1.5
Mean Putamen Volume 1.6 1.9 4.0 -0.2 1.1 0.2 1.1 1.8 1.1 -1.5 2.0 1.9
Fasting Glucose 0.3 0.4 1.2 1.1 0.6 0.1 -0.6 0.1 0.1 0.4 -1.1 -0.0
HbA1C 0.2 0.2 1.0 1.0 0.2 0.4 -0.3 -0.5 0.1 0.5 0.3 0.5
HDL Cholesterol 0.5 0.9 3.0 -1.1 0.3 0.8 1.0 0.4 0.7 1.1 1.7 -0.7
LDL Cholesterol 2.9 4.5 11.1 1.5 -1.6 -2.6 -1.7 -1.6 -2.0 2.1 -3.3 -2.0
Lupus 0.4 0.6 2.9 -1.7 0.3 -0.5 0.8 0.4 0.7 0.4 0.0 0.7
Neuroticism (2016) 0.5 0.7 2.7 0.9 0.7 1.6 -0.4 0.2 1.1 -0.2 0.3 1.0
Primary Biliary Cirrhosis 0.1 0.1 0.2 -0.2 0.5 0.3 0.2 0.2 0.3 -0.5 0.4 0.4
Rheumatoid Arthritis 1.2 1.7 4.9 -1.4 -1.3 -2.2 -0.4 -1.3 -0.6 0.3 -1.9 -1.1
Schizophrenia (2014) 0.6 1.3 6.2 -0.1 0.8 1.4 0.4 0.4 1.4 2.5 -0.2 0.6
Triglycerides 0.7 1.1 2.5 1.5 -0.8 -1.0 -1.6 -1.6 -1.1 0.1 -0.3 -0.0
Type 2 Diabetes (T2D) (2012) 0.7 0.8 2.5 1.0 0.2 0.4 -1.1 -0.4 -1.0 -1.6 -0.5 -0.7
Ulcerative Colitis 1.6 2.4 6.6 0.7 -1.5 -0.4 -2.4 -1.8 -1.1 0.4 -2.6 -1.1
Blood Eosinophil Count 0.7 5.5 8.5 -2.2 2.8 -0.5 2.8 1.6 2.9 2.1 2.9 2.2
Blood Platelet Count 0.2 2.4 4.4 2.1 -1.2 -1.6 -1.8 -1.2 -1.8 -0.9 -2.0 -0.7
Blood Red Count 0.7 6.4 16.2 1.5 2.6 4.0 2.5 1.8 2.4 -1.6 2.7 2.8
Blood White Count 1.3 9.5 22.9 4.8 -3.2 -2.7 -4.1 -3.8 -3.0 0.6 -0.6 -1.9
Heel T-Score 0.5 3.9 14.9 -3.9 2.0 -0.1 2.6 1.1 1.4 -1.2 -1.2 1.8
BMI 0.3 1.6 4.7 -1.0 0.9 -1.1 1.9 1.4 0.3 2.2 1.0 -0.5
Height 1.5 29.2 97.4 -0.8 6.4 9.9 4.3 5.5 5.1 -1.9 4.5 5.1
Waist Hip Ratio (WHR) 0.1 0.5 3.7 -0.3 0.2 -0.3 0.1 -0.1 0.4 1.9 -0.4 -0.4
Systolic Blood Pressure 0.7 3.3 6.6 -0.4 -1.8 -2.2 -1.2 -1.8 -2.6 -0.2 -2.4 -2.1
Smoking Status 1.3 3.0 11.8 3.4 -2.0 -0.2 -1.9 -2.2 -0.7 0.1 1.4 -0.9
Allergy or Eczema 0.2 0.6 1.8 0.6 -0.1 0.6 -0.5 -1.1 0.7 -1.4 -0.2 0.6
Cardiovascular Disease 0.4 1.2 2.3 -0.5 -1.3 -0.5 -1.4 -1.0 -1.4 0.5 -1.5 -0.9
Hypothyroidism (self reported) 0.6 1.4 4.1 -2.0 0.8 -0.6 1.6 1.3 1.4 0.4 1.1 0.4
Respiratory disease 0.1 0.3 1.1 0.1 -0.5 -0.8 -1.0 -0.6 0.4 -0.5 0.3 -0.3
Type 2 Diabetes (T2D) (2018) 0.5 0.9 4.5 0.1 0.8 0.1 0.8 0.9 0.9 0.1 2.1 0.6
Lung FEV1/FVC ratio 1.0 5.2 14.9 -3.9 2.3 1.4 3.0 2.2 1.8 0.9 1.4 2.1
Lung FVC 1.4 7.3 13.5 3.7 -2.7 -2.5 -3.3 -2.5 -3.1 -0.9 -2.4 -2.4
Neuroticism 1.7 4.2 6.7 -0.8 2.4 2.6 1.5 2.2 2.1 -1.8 1.8 2.6
Chronotype (morning person) 0.2 0.5 1.8 -0.2 0.6 -0.4 0.4 1.2 -0.5 0.0 -1.4 -0.2
Hair Pigment 0.0 0.2 1.0 1.0 0.2 -0.4 -0.4 -0.4 0.2 0.4 0.1 0.1
Tanning 0.2 2.0 5.3 1.2 -1.1 -1.2 -2.3 -1.6 -1.2 -1.1 -1.6 -0.7
Hand grip strength (left) 0.5 1.2 3.4 1.8 -0.1 -0.7 -1.4 -1.0 -0.4 -1.9 0.7 0.4
Number of treatments/medications taken 0.2 0.3 0.7 -0.9 0.5 0.2 0.8 -0.1 0.3 -0.3 0.8 0.6
Average weekly spirits intake 0.5 0.6 2.4 -1.5 0.0 0.7 1.1 0.2 -0.2 -0.9 0.7 -0.3
Sensitivity / hurt feelings 1.2 2.0 3.7 -0.8 1.3 1.4 1.7 1.8 1.6 -1.0 0.4 1.9
Frequency of depressed mood in last 2 weeks 0.5 0.7 1.8 -0.0 0.6 0.9 1.2 0.9 1.1 -0.3 0.4 1.3
Hearing difficulty/problems: Yes 0.2 0.4 1.3 0.3 0.2 0.1 0.3 0.2 0.7 1.2 1.0 0.5
Relative age of first facial hair 0.7 1.5 5.4 0.5 -0.9 -0.8 -0.4 -0.9 -0.5 2.3 -1.9 -1.2
Other serious medical condition/disability diagnosed by doctor 0.9 1.2 2.4 -0.3 1.5 0.9 1.2 1.5 0.8 0.1 1.4 1.0
Ever used hormone-replacement therapy (HRT) 0.6 0.8 1.3 0.8 -1.1 -1.1 -0.9 -0.9 -1.0 -0.6 -0.7 -1.0
Ever had hysterectomy (womb removed) 1.1 1.2 2.3 -0.1 1.3 0.6 1.0 1.4 1.0 -1.5 1.2 1.2
Systolic blood pressure, automated reading 0.3 0.7 3.8 -1.9 0.2 -0.8 1.2 0.2 -0.2 0.3 -0.6 -0.3
Eye problems/disorders: Diabetes related eye disease 0.4 0.4 1.0 -0.4 0.9 0.8 0.4 1.0 0.6 -0.3 -0.5 0.5
Angina 6.7 8.8 16.0 3.3 -3.8 -1.6 -3.6 -4.0 -2.6 1.0 -2.6 -2.8
Medication for hormone replacement therapy 1.0 1.1 3.2 -0.1 -1.3 -1.4 -0.1 -1.4 -0.5 1.8 -1.0 -0.5
Vitamin and mineral supplements 0.6 0.8 2.4 1.5 -1.2 -0.1 -1.1 -0.5 -0.8 0.9 -0.4 -0.7
Supplements: Zinc 0.3 0.4 0.7 0.2 0.7 0.2 0.8 0.8 0.6 0.5 0.7 0.4
Medication: Co-codamol 0.3 0.3 1.7 0.8 0.0 -0.0 -0.2 -0.4 0.2 1.3 -0.3 0.4
Medication: Metformin 0.2 0.3 2.0 0.3 0.1 -0.2 0.5 0.4 0.2 0.1 1.4 0.0
Diabetes (father) 0.6 0.7 1.4 0.2 -0.3 1.2 0.4 -0.9 0.9 -1.2 1.1 0.8
Diabetes (mother) 0.4 0.5 1.9 0.8 0.5 0.8 0.3 -0.8 -0.0 1.4 0.5 0.2
Severe depression (siblings) 0.1 0.1 0.2 0.2 0.4 0.4 -0.2 0.2 0.3 -0.2 0.2 0.0
Pack years adult smoking proportion 0.7 1.0 3.6 0.5 0.5 1.2 0.1 0.6 1.2 0.2 1.9 1.3
Impedance of leg (right) 1.5 7.1 11.2 1.9 -3.4 -2.5 -3.0 -3.0 -3.0 -0.6 -3.0 -2.6
Leg fat-free mass (left) 2.4 12.7 20.5 -2.2 4.5 4.5 4.1 4.1 3.5 1.0 3.5 3.2
Trunk fat percentage 0.7 2.6 12.2 -1.7 0.6 -0.4 2.4 1.5 0.5 3.5 0.3 -0.5
Hand grip strength (right) 0.6 1.5 5.4 1.4 0.7 0.6 -0.4 -0.4 0.5 -2.3 1.5 1.6
Townsend deprivation index at recruitment 0.2 0.2 1.1 0.1 0.1 0.1 -0.0 0.4 0.4 1.1 0.7 0.4
Current tobacco smoking 1.0 1.6 5.6 2.0 -0.3 1.3 -0.0 -0.6 1.1 0.1 2.4 1.0
Average weekly fortified wine intake 2.1 2.5 7.2 -1.3 1.9 2.7 1.4 1.6 1.6 -0.7 0.5 1.5
Maternal smoking around birth 1.3 1.9 4.2 2.1 -1.8 -1.2 -2.0 -1.3 -0.8 -0.9 0.0 -1.0
Fed-up feelings 0.9 1.6 4.9 0.8 1.4 2.2 0.6 0.0 1.6 0.3 1.0 1.6
Frequency of unenthusiasm / disinterest in last 2 weeks 0.7 0.9 3.3 0.6 -0.1 1.8 0.2 0.1 1.3 0.9 0.2 1.3
Relative age voice broke 0.8 1.3 5.8 -0.1 -1.1 -0.8 0.2 0.1 -0.2 2.4 -1.6 -1.0
Taking other prescription medications 0.2 0.3 1.3 -0.1 0.7 -0.2 0.5 0.3 0.6 1.1 0.4 0.0
Age when periods started (menarche) 0.7 1.7 3.9 0.3 0.9 1.9 1.2 0.7 1.5 2.0 1.2 1.3
Bilateral oophorectomy (both ovaries removed) 1.0 1.1 6.7 2.6 0.0 0.5 -1.1 -0.7 -0.5 0.8 -0.7 0.5
Heel bone mineral density (BMD) T-score, automated (left) 0.4 0.8 2.2 -0.2 1.2 0.5 0.5 1.5 0.2 -1.1 -1.1 1.0
Tinnitus: Yes, but not now, but have in the past 1.3 1.3 5.2 2.3 -0.9 -0.6 -0.4 -1.2 -1.3 0.9 -0.0 -1.3
Qualifications: CSEs or equivalent 0.6 0.8 2.1 -0.1 1.2 0.2 0.1 1.1 0.6 -1.1 -0.4 1.5
Serious illness, injury or assault to yourself 0.9 1.0 3.7 -0.3 -0.4 -1.9 -0.8 -0.2 -1.6 0.1 -0.2 -1.4
High blood pressure 0.2 0.7 2.4 -1.5 0.6 0.3 0.7 1.0 0.6 0.9 -0.3 0.7
Hayfever, allergic rhinitis or eczema 0.1 0.3 1.2 0.6 -0.1 0.4 -0.2 -0.7 0.4 -1.1 -0.3 0.5
Multivitamins +/- minerals 0.4 0.5 1.3 -1.1 1.0 0.2 0.7 0.1 0.9 -0.6 0.3 0.8
Stomach or abdominal pain in last month 0.1 0.2 0.4 0.5 -0.5 0.1 -0.6 -0.1 0.1 0.0 0.6 0.4
Supplements: Glucosamine 0.2 0.3 0.8 -0.9 0.0 -0.7 0.4 -0.6 0.2 0.3 -0.5 0.2
Diverticular disease/diverticulitis (self-reported) 1.5 1.7 5.7 0.8 -0.6 -0.8 -1.9 -1.2 -1.7 -2.4 -0.6 -0.1
Medication: Atenolol 4.0 5.0 7.6 1.2 -2.5 -2.8 -2.6 -1.9 -2.6 0.6 -2.4 -2.5
Medication: Levothyroxine sodium 0.7 1.2 5.7 -2.4 0.7 -0.6 1.5 0.8 0.9 0.9 0.1 0.3
Sitting height 0.6 4.0 17.5 -0.7 2.4 4.2 1.2 1.9 1.3 -1.4 1.4 1.0
Chronic bronchitis/emphysema (father) 0.7 0.8 4.8 0.2 -0.7 -0.3 -0.3 -0.3 -0.3 -2.2 1.4 0.0
High blood pressure (mother) 0.1 0.2 0.7 0.2 0.3 0.8 0.2 0.4 0.3 0.3 0.4 0.5
Body mass index (BMI) 0.7 3.1 7.1 -1.8 1.8 0.3 2.7 2.4 1.2 2.4 0.9 0.6
Impedance of leg (left) 1.5 7.5 10.9 2.6 -3.3 -2.6 -3.1 -2.9 -2.9 -0.6 -3.1 -2.5
Leg predicted mass (left) 2.5 13.4 21.5 -2.2 4.6 4.5 4.3 4.2 3.6 1.0 3.5 3.3
Trunk fat mass 0.8 3.6 9.3 -1.7 1.7 1.0 2.9 2.4 1.2 3.0 0.9 0.3
Waist circumference 1.5 5.4 10.6 -2.1 2.5 1.6 3.3 3.0 2.1 2.8 1.5 1.1
Number of incorrect matches in round 0.7 1.2 7.2 0.7 -1.2 -0.3 -0.3 -0.3 -0.1 2.7 0.0 -1.2
Past tobacco smoking 1.2 2.3 3.7 -1.9 1.5 1.9 1.3 1.8 1.0 -1.9 0.5 1.1
Alcohol usually taken with meals 0.6 0.9 2.1 -0.6 0.3 -0.8 -0.7 -1.0 -1.1 -1.4 -1.5 -0.4
Nervous feelings 1.0 1.9 7.4 0.3 1.3 2.7 1.1 0.7 1.5 -0.5 1.1 1.6
Frequency of tenseness / restlessness in last 2 weeks 0.3 0.5 1.3 0.8 0.3 0.9 0.2 -0.4 0.7 0.9 0.0 1.1
Hearing difficulty/problems with background noise 0.4 0.7 2.1 -0.0 0.2 0.4 0.8 0.9 0.5 1.5 1.3 -0.2
Hair/balding pattern: Pattern 2 0.7 0.9 3.4 0.4 -0.3 -0.6 -0.9 0.1 -1.1 -1.1 -1.9 -0.8
Had menopause 0.1 0.1 0.7 -0.3 0.0 0.3 0.4 -0.0 -0.1 -0.8 -0.3 -0.1
Had other major operations 0.9 1.1 4.2 -2.0 0.8 -0.3 1.2 1.2 0.6 1.4 -0.1 0.3
Forced vital capacity (FVC) 0.5 1.9 5.7 2.4 -0.5 0.5 -1.8 -0.8 -1.5 -1.7 -0.9 -1.0
Heel bone mineral density (BMD) T-score, automated (right) 0.8 1.8 5.5 -1.1 1.6 0.6 1.4 2.4 0.7 -0.5 -1.1 1.4
Ever unenthusiastic/disinterested for a whole week 0.3 0.4 2.2 0.4 1.5 0.1 0.4 0.3 -0.2 -0.6 -0.2 0.6
Qualifications: None of the above 0.4 0.9 3.1 1.8 -0.7 0.5 -0.1 -0.5 0.6 1.5 1.1 0.1
Financial difficulties in last 2 years 0.7 1.0 6.6 1.1 0.4 -0.4 0.1 0.2 0.4 2.6 0.5 0.2
Mouth/teeth dental problems 0.6 0.9 4.5 0.7 0.2 1.1 0.2 0.4 0.3 -1.2 2.1 0.6
Heart attack 0.1 0.1 0.3 -0.2 0.1 -0.4 0.2 0.0 0.1 0.1 -0.5 0.1
Allergy 0.1 0.1 0.5 -0.7 0.1 0.3 0.3 0.2 0.0 0.5 0.3 -0.1
Pain all over the body in last month 0.3 0.3 1.0 -1.0 0.7 0.5 0.2 0.4 0.4 0.9 0.4 -0.0
Diabetes (self-reported) 0.6 0.9 3.1 -0.6 0.8 0.8 1.2 1.8 0.6 -0.2 1.3 0.6
Hayfever/allergic rhinitis (self-reported) 0.3 0.4 1.4 0.2 -0.1 0.4 0.5 -0.3 1.2 -0.9 0.8 0.7
Medication: Ramipril 0.3 0.4 1.1 -0.2 -0.1 -0.3 -0.2 0.7 -1.1 0.8 -0.5 -0.9
Medication: Simvastatin 0.7 1.0 6.2 -0.6 -0.6 -0.2 0.1 0.5 -0.0 2.5 -1.2 0.2
Fluid intelligence score 0.6 1.2 3.2 -1.8 0.9 1.1 1.3 1.0 0.7 -1.3 0.3 0.9
Illnesses of siblings 0.5 0.7 3.3 -0.6 0.6 1.8 0.4 0.9 0.6 -0.8 0.3 0.9
Neuroticism score 1.3 2.6 4.9 0.3 1.6 2.2 1.3 1.3 1.9 -1.3 1.6 2.2
Weight 1.8 9.1 15.9 -1.9 3.8 3.4 4.0 3.9 2.7 1.7 2.4 2.1
Impedance of arm (right) 0.3 1.6 4.4 -0.1 -1.7 -1.3 -0.8 -2.1 -1.3 0.6 -1.1 -1.3
Arm fat percentage (right) 0.7 2.8 12.5 -1.8 0.7 -0.4 2.4 1.5 0.7 3.5 0.4 -0.4
Trunk fat-free mass 2.4 13.8 32.6 -0.9 4.9 5.7 3.6 4.2 3.6 -0.5 3.2 3.6
Hip circumference 1.1 4.6 8.4 -1.6 2.4 2.2 2.9 2.8 1.9 2.0 1.8 1.1
Time employed in main current job 0.4 0.5 2.1 -1.4 0.4 -0.1 0.9 -0.2 0.8 -0.4 0.6 0.0
Alcohol intake versus 10 years previously 2.6 3.9 8.6 -1.5 2.1 1.2 2.0 2.2 2.1 -0.5 2.9 2.1
Father’s age at death 2.7 3.6 9.3 -1.2 1.6 3.0 1.8 1.8 2.0 -1.5 1.8 1.9
Worrier / anxious feelings 0.4 0.8 2.3 -0.6 0.8 1.5 0.8 1.1 0.8 -0.7 -0.3 0.8
Frequency of tiredness / lethargy in last 2 weeks 5.2 8.4 13.6 -1.5 3.1 3.7 3.2 2.6 3.6 0.8 2.5 3.6
Falls in the last year 0.3 0.4 1.1 0.3 0.3 0.1 0.6 1.1 0.7 -0.9 0.2 0.7
Hair/balding pattern: Pattern 3 1.9 2.8 7.3 1.7 -2.7 -1.5 -1.4 -2.5 -1.3 0.2 -1.3 -1.1
Number of live births 0.8 1.1 1.9 0.6 -1.3 -1.0 -1.0 -0.1 -1.3 -1.2 -0.6 -1.4
Forced expiratory volume in 1-second (FEV1) 0.2 0.7 2.3 1.2 0.3 0.8 -0.8 -0.1 -0.9 -1.5 -0.6 -0.3
Pulse rate 0.1 0.2 0.4 -0.3 0.5 -0.3 0.7 0.5 0.1 -0.4 0.5 0.6
Happiness 1.0 1.2 3.8 -1.0 1.5 0.1 1.9 1.0 0.9 1.0 0.6 0.8
Noisy workplace 2.6 3.1 5.2 2.0 -2.2 -2.3 -1.6 -2.3 -2.0 -0.5 -0.2 -1.5
Qualifications: A levels/AS levels or equivalent 1.1 2.3 5.7 -2.4 1.9 0.6 2.4 1.4 1.0 -1.2 0.4 1.0
Serious illness, injury or assault of a close relative in last 2 years 0.2 0.2 0.9 0.5 0.0 -0.7 -0.6 0.2 -0.4 -0.9 0.2 0.1
Mouth/teeth dental problems: Dentures 1.2 2.0 6.5 0.5 -1.9 -1.1 -1.3 -1.3 -1.1 0.1 -2.5 -1.3
Asthma 0.0 0.1 0.2 -0.2 -0.1 -0.3 -0.4 0.3 0.5 0.5 0.1 0.1
Medication: Ibuprofen (e.g. Nurofen) 0.5 0.6 1.7 0.0 1.0 0.1 0.5 0.6 0.8 0.4 1.3 1.1
Medication: Cholesterol lowering 0.1 0.2 0.5 -0.3 -0.7 -0.2 -0.3 -0.5 -0.7 0.1 -0.7 -0.2
Depression (self-reported) 0.3 0.3 0.9 0.6 0.8 0.5 0.5 0.3 0.7 -0.2 -0.2 1.0
Medication: Lansoprazole 0.2 0.3 0.6 0.8 -0.6 -0.7 -0.3 -0.1 -0.6 -0.1 0.5 -0.4
Prospective memory result 0.6 0.7 1.7 1.3 -0.9 0.6 -0.2 -1.3 -0.3 1.1 0.4 -0.8
Lung cancer (father) 2.0 2.3 5.0 -1.8 1.5 0.9 2.2 1.3 1.6 0.7 1.8 1.3
Illnesses of mother 0.9 1.2 3.3 -1.8 1.2 0.6 1.0 1.2 0.7 -1.0 0.6 1.0
Forced expiratory volume in 1-second (FEV1), Best measure 0.2 0.6 2.0 1.2 0.8 1.4 -0.5 0.2 -0.2 -1.1 0.2 0.3
Pulse wave Arterial Stiffness index 0.3 0.3 0.7 0.6 -0.4 -0.9 -0.4 -0.7 -0.7 -0.2 -0.7 -0.4
Impedance of arm (left) 0.3 1.5 3.6 -0.5 -1.8 -1.4 -0.7 -1.9 -1.3 0.6 -0.7 -1.3
Arm fat mass (right) 0.9 3.6 8.3 -1.7 1.9 0.9 2.8 2.3 1.4 2.9 1.2 0.4
Trunk predicted mass 2.5 14.2 33.6 -0.9 4.9 5.8 3.6 4.3 3.7 -0.5 3.3 3.6
Standing height 1.5 14.6 48.2 -0.4 4.8 6.9 3.2 3.4 3.5 -1.4 3.2 3.5
Length of working week for main job 0.3 0.4 1.8 1.4 -0.8 0.1 -0.6 -0.4 -0.5 -0.3 0.0 -0.1
Exposure to tobacco smoke at home 0.3 0.3 1.0 0.5 -0.7 -0.3 -1.0 -0.5 -0.2 0.3 -0.6 -0.7
Breastfed as a baby 0.5 0.7 3.6 -1.9 0.5 0.5 1.0 -0.2 0.7 0.2 0.1 0.7
Tense / ‘highly strung’ 0.7 1.1 2.7 0.1 0.9 1.1 1.6 0.3 1.3 1.6 0.3 0.9
Seen doctor (GP) for nerves, anxiety, tension or depression 2.1 3.2 6.1 -1.4 1.8 2.5 1.9 2.1 1.9 -1.3 0.6 2.0
Hair/balding pattern: Pattern 4 3.9 9.3 14.9 -3.8 3.4 2.6 3.0 3.5 3.3 0.2 3.9 2.1
Birth weight of first child 0.6 1.1 2.8 0.2 1.2 1.6 0.6 0.5 1.2 -0.6 0.8 1.7
Peak expiratory flow (PEF) 0.0 0.1 0.2 0.3 0.2 0.2 -0.4 -0.4 -0.2 0.1 0.0 -0.2
Pulse wave reflection index 0.1 0.2 0.4 0.1 -0.6 -0.5 0.2 0.2 -0.3 0.7 0.1 -0.5
Ever highly irritable/argumentative for 2 days 1.5 1.8 4.4 1.9 -0.7 -2.1 -1.5 -1.9 -1.3 0.1 0.5 -0.6
Loud music exposure frequency 0.7 0.7 2.2 -1.5 1.2 0.1 0.8 0.1 0.5 -1.1 0.5 0.8
Qualifications: O levels/GCSEs or equivalent 1.0 1.6 6.2 -2.5 1.3 -0.3 1.6 1.0 1.0 -0.3 -0.1 1.2
Mouth/teeth dental problems: Bleeding gums 0.4 0.5 2.2 -0.5 0.2 -0.7 -0.4 -0.3 -0.4 1.5 -0.9 -0.4
Blood clot in the leg (DVT) 0.4 0.5 2.5 1.0 0.2 0.1 -0.3 0.3 -0.6 -1.6 0.5 0.3
Medication: Paracetamol 0.5 0.8 2.2 0.0 1.0 1.5 0.8 0.3 0.9 0.1 1.0 1.2
Headache pain in last month 1.3 2.3 4.7 0.8 1.5 1.5 0.5 0.5 1.6 -1.9 2.2 2.0
Medication for cholesterol, blood pressure or diabetes 0.7 1.1 2.3 -0.4 1.1 1.4 0.8 1.4 1.5 0.2 0.9 1.0
Glaucoma (self-reported) 2.5 2.9 5.7 -0.8 1.4 2.4 2.0 2.0 1.7 1.2 2.0 1.4
Gout (self-reported) 1.4 2.0 3.8 1.9 -1.6 -1.1 -1.6 -1.5 -1.1 1.1 -0.8 -1.6
Hypothyroidism/myxoedema (self-reported) 0.6 1.2 4.6 -2.2 0.4 -0.6 1.3 1.0 0.8 1.3 -0.5 -0.3
Medication: Amlodipine 0.3 0.5 1.6 -0.1 -0.2 -1.2 -0.8 0.4 -0.3 -1.3 0.3 -0.3
Medication: Ventolin 100micrograms inhaler 0.5 0.7 1.9 0.4 -1.1 -1.4 -0.8 -1.4 -0.1 -0.4 -0.2 -0.6
Birth weight 0.8 1.8 4.9 1.0 0.6 2.1 -0.8 -0.7 0.2 -2.2 2.0 0.3
Chronic bronchitis/emphysema (mother) 0.9 1.0 1.7 0.4 -1.3 -1.1 -1.3 -0.9 -1.2 -1.1 0.4 -1.0
High blood pressure (siblings) 0.5 0.8 3.7 0.5 -0.5 -1.9 -0.8 -0.6 -0.9 -0.1 -0.7 -0.7
Forced vital capacity (FVC), Best measure 0.5 1.7 6.8 2.6 -0.2 1.0 -1.8 -0.8 -0.9 -1.5 -0.4 -0.6
Body fat percentage 0.6 2.3 11.8 -1.4 0.3 -0.7 1.9 1.3 0.1 3.4 -0.3 -0.8
Leg fat percentage (right) 0.6 2.1 10.6 -1.0 0.0 -1.4 1.3 1.1 -0.4 3.2 -0.9 -1.2
Arm fat-free mass (right) 2.1 10.8 23.8 -1.0 4.3 4.9 3.2 4.1 3.2 0.0 2.7 3.1
Exposure to tobacco smoke outside home 0.4 0.5 2.2 -1.5 -0.0 0.4 0.5 0.0 0.5 1.3 -0.4 0.5
Comparative body size at age 10 0.4 1.0 3.6 0.4 1.0 1.5 0.4 0.8 0.6 0.4 1.9 0.8
Number of full brothers 0.2 0.3 1.1 -0.4 0.2 0.4 0.6 0.4 0.8 0.4 1.1 0.1
Worry too long after embarrassment 0.7 1.1 2.0 0.6 1.0 1.2 0.8 1.4 0.9 -1.1 1.3 1.1
Seen a psychiatrist for nerves, anxiety, tension or depression 0.9 1.2 4.7 -0.4 1.0 2.2 1.0 0.6 1.6 -0.1 0.5 0.7
Wheeze or whistling in the chest in last year 0.3 0.5 1.4 0.6 0.1 0.2 0.0 -0.8 1.0 -0.4 1.2 0.9
Number of children fathered 0.2 0.2 0.7 0.3 0.6 -0.8 0.3 0.2 0.1 0.9 -0.5 -0.0
Reason for reducing amount of alcohol drunk: Health precaution 5.4 6.3 10.6 1.7 -2.4 -1.8 -3.0 -2.4 -2.9 0.6 -3.2 -3.2
Age at first live birth 0.6 1.0 4.6 -2.1 0.9 0.8 0.7 0.4 0.7 -0.7 0.8 0.8
Pulse wave peak to peak time 0.6 0.7 1.8 -0.7 0.8 1.4 0.6 1.0 1.0 0.0 0.8 0.7
Health satisfaction 2.1 2.7 6.2 1.3 -1.0 -1.2 -2.0 -1.7 -2.3 0.6 -0.9 -2.5
Shortness of breath walking on level ground 0.3 0.3 1.2 1.1 -0.3 -0.2 -0.3 -0.2 -0.2 0.9 0.2 -0.8
Qualifications: College or University degree 0.5 1.6 9.9 -1.6 0.7 0.8 0.5 0.6 -0.2 -3.1 0.1 0.3
Eye problems/disorders: None of the above 0.4 0.5 1.1 -0.3 -0.7 -0.8 -0.7 -0.3 -1.0 0.2 -1.1 -0.6
Mouth/teeth dental problems: Loose teeth 0.5 0.5 4.3 0.1 0.5 -0.2 0.3 0.0 -0.1 2.1 0.4 -0.2
Emphysema/chronic bronchitis 0.3 0.3 0.7 0.7 0.8 0.1 -0.1 0.2 0.6 -0.7 0.7 0.5
Medication for pain relief, constipation, heartburn 0.6 1.0 4.0 -0.7 -0.9 -1.1 -0.6 -0.7 -0.8 -0.5 -2.0 -1.0
Neck or shoulder pain in last month 0.2 0.3 0.9 0.9 -0.2 -0.3 -0.9 -0.5 -0.0 0.8 0.6 -0.2
Medication: Blood pressure 1.9 3.4 6.5 0.6 -1.9 -2.5 -1.7 -2.0 -2.5 0.0 -1.5 -2.2
Angina (self-reported) 5.8 7.7 14.5 3.0 -3.6 -1.6 -3.4 -3.8 -2.2 1.1 -2.4 -2.7
Migraine (self-reported) 0.2 0.3 1.7 -0.4 0.0 0.2 -0.5 -0.2 -0.3 -1.3 -0.0 -0.2
Medication: Ibuprofen 0.4 0.5 1.4 0.8 0.8 0.5 -0.1 -0.1 0.4 -0.6 1.1 1.2
Medication: Allopurinol 0.9 1.2 3.2 1.8 -1.1 -0.4 -1.1 -1.3 -1.0 0.4 -0.6 -1.5
Medication: Omeprazole 0.6 0.7 1.8 -0.2 1.3 1.1 -0.1 0.5 0.4 -0.5 1.3 0.7
Medication: Seretide 50 evohaler 2.7 3.1 5.4 2.3 -1.9 -1.2 -2.2 -1.8 -1.7 -2.3 0.1 -1.2
Mean time to correctly identify matches 0.4 0.8 1.9 0.5 -0.8 -1.4 -0.6 -1.3 -0.8 0.7 0.0 -1.0
Heart disease (mother) 0.2 0.3 0.8 0.6 0.6 0.9 0.3 0.5 0.7 0.3 0.3 0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.1 1.3 8.6 0.1 -0.7 0.4 -0.3 -0.6 -0.4 -2.9 1.5 0.3
Whole body fat mass 0.8 3.3 7.7 -1.6 1.8 0.9 2.7 2.4 1.1 2.8 0.9 0.4
Leg fat mass (right) 0.5 2.0 7.8 -1.0 1.2 0.1 2.0 1.8 0.6 2.8 0.4 -0.1
Arm predicted mass (right) 1.9 9.8 22.7 -0.8 4.1 4.8 3.0 3.9 3.0 -0.1 2.7 2.9
Pulse rate, automated reading 0.2 0.6 2.9 0.1 -0.6 -1.7 -0.3 0.4 -0.9 -0.5 -1.0 -0.4
Alcohol intake frequency. 9.4 21.9 35.4 -3.1 5.4 3.7 5.9 4.3 5.5 -1.5 5.2 5.6
Comparative height size at age 10 1.1 6.0 15.0 -1.1 3.3 3.9 2.3 3.1 1.6 -1.1 2.2 1.5
Number of full sisters 0.5 0.6 2.2 1.5 -0.6 0.3 -0.7 -0.2 -1.0 0.6 -0.5 -0.8
Suffer from ‘nerves’ 0.3 0.4 1.6 1.3 -0.1 0.8 -0.6 -0.7 0.2 -0.7 0.4 0.5
Overall health rating 0.3 0.6 2.3 0.5 0.3 0.4 0.2 0.1 0.8 1.5 1.4 0.3
Chest pain or discomfort 0.6 0.8 2.1 1.4 0.2 -0.0 0.6 -0.4 1.0 1.4 1.2 0.7
Had major operations 0.3 0.3 2.2 1.5 0.1 -0.1 0.2 -0.4 -0.4 -0.5 -0.2 0.5
Age at last live birth 1.0 1.4 6.4 -1.2 0.9 1.6 -0.1 0.8 0.4 -2.5 0.0 0.9
Family relationship satisfaction 1.8 2.3 5.1 -0.9 1.9 1.0 2.0 0.9 1.6 2.2 1.3 1.0
Leg pain on walking 0.1 0.2 0.9 0.0 0.5 0.9 0.3 -0.5 -0.5 -0.2 0.1 0.1
Qualifications: NVQ or HND or HNC or equivalent 2.0 2.4 4.8 1.4 -1.2 -1.1 -1.9 -2.1 -1.0 2.2 -1.7 -1.0
Commuting to job workplace: Car/motor vehicle 0.1 0.1 0.3 0.4 0.3 -0.6 0.3 -0.1 0.1 -0.4 0.6 0.1
Illness, injury, bereavement, stress in last 2 years 0.5 0.7 2.8 -1.7 -0.7 1.0 0.5 -1.0 0.5 0.3 -0.1 -0.4
Medication: Aspirin 0.2 0.3 0.8 -0.5 -0.1 0.1 0.6 0.8 -0.1 0.9 0.3 -0.3
Supplements: Vitamin C 0.4 0.4 1.8 -1.0 0.6 0.5 0.7 0.3 0.1 -1.4 -0.1 0.2
Knee pain experienced in last month 2.0 3.1 4.7 -0.8 1.5 1.9 2.1 1.3 2.2 2.0 1.8 1.9
Hypertension (Self-reported) 0.1 0.3 1.4 -1.2 0.3 0.3 0.3 0.8 0.1 0.6 -0.5 0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.8 0.9 2.0 -0.0 1.3 0.8 1.1 1.4 0.8 0.6 1.1 0.9
Illnesses of father: Heart disease 0.8 1.2 3.0 1.0 -1.4 -0.9 -1.7 -0.2 -1.4 -0.4 -0.9 -0.8
Illnesses of siblings: Diabetes 0.4 0.5 1.3 0.9 -0.3 -0.8 -0.4 -0.5 -0.1 1.1 0.8 -0.4
Smoking status: Previous 2.1 3.1 5.4 1.7 -1.7 -2.3 -1.5 -1.6 -1.6 1.9 -1.4 -1.9
Forced expiratory volume in 1-second (FEV1), predicted 0.5 1.0 3.7 0.9 1.4 1.9 0.3 1.0 0.1 -0.6 0.1 1.0
Whole body fat-free mass 2.6 14.6 30.2 -1.4 4.9 5.5 4.0 4.5 3.8 0.1 3.5 3.6
Leg fat-free mass (right) 2.7 14.4 23.7 -2.1 4.9 4.8 4.3 4.5 3.8 0.7 3.5 3.6
Arm fat percentage (left) 0.7 2.8 11.4 -2.1 0.7 -0.4 2.4 1.5 0.5 3.4 0.4 -0.4
Average weekly red wine intake 0.5 0.7 1.8 0.3 -0.4 -0.1 -1.0 -0.5 -1.3 -1.3 -0.7 -1.0
Handedness (chirality/laterality): Left-handed 0.6 0.7 1.4 -0.3 0.6 1.2 1.2 1.2 0.8 0.6 0.5 0.7
Mood swings 1.0 1.8 5.2 1.6 0.8 1.6 0.4 0.9 1.6 -1.0 1.0 2.3
Loneliness, isolation 0.6 0.8 2.0 1.1 -1.0 1.3 -1.0 -1.4 0.2 -0.2 -0.2 0.0
Long-standing illness, disability or infirmity 0.4 0.6 1.6 -0.5 1.0 -0.6 0.2 0.2 0.3 -1.0 1.2 0.8
Ever had bowel cancer screening 1.0 1.2 2.5 0.4 1.2 1.4 1.6 1.3 0.8 0.5 1.0 1.1
Diabetes diagnosed by doctor 0.4 0.6 1.7 -0.7 0.2 -0.4 0.9 0.7 0.6 1.1 1.3 -0.0
Ever had stillbirth, spontaneous miscarriage or termination 0.4 0.4 0.8 0.9 -0.1 0.5 -0.5 -0.5 -0.9 0.5 -0.8 -0.4
Friendships satisfaction 0.6 0.7 1.6 -0.3 1.3 0.9 0.9 0.8 1.0 0.7 0.9 0.7
Qualifications: nursing, teaching 0.5 0.8 3.0 -1.7 0.8 -1.2 1.0 0.8 0.3 -0.3 0.2 -0.0
Commuting to job workplace: Walk 0.3 0.3 0.8 -0.5 0.9 0.7 0.4 0.5 0.7 0.5 0.1 0.2
Eye problems/disorders: Cataract 0.4 0.5 1.4 0.7 0.2 -0.6 0.0 -1.2 0.5 1.0 0.8 0.3
Mouth/teeth dental problems: Mouth ulcers 1.4 2.2 4.1 -2.0 1.8 0.6 1.6 1.9 1.7 0.2 0.3 1.5
Medication for cholesterol 1.0 1.5 7.3 0.6 0.6 1.3 0.3 0.1 0.9 -2.7 1.6 0.4
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.8 1.0 2.8 1.7 -0.5 -1.0 -1.3 -0.8 -0.7 -1.1 0.3 -0.7
Back pain experienced in last month 0.1 0.1 0.5 0.1 0.7 0.3 0.1 0.1 -0.2 0.7 -0.2 -0.3
Mineral and other dietary supplements 0.1 0.1 0.4 0.6 -0.3 0.2 -0.3 -0.0 -0.4 -0.3 -0.1 -0.3
Breast cancer (self-reported) 0.3 0.3 1.2 -1.0 0.0 0.0 0.5 0.3 0.7 1.1 -0.2 0.1
Asthma (self-reported) 0.0 0.1 0.3 -0.1 -0.2 -0.4 -0.3 0.2 0.6 0.3 0.2 0.2
Osteoporosis (self-reported) 0.5 0.6 1.4 0.4 -1.0 -0.4 -0.9 -1.1 -0.6 -1.2 -0.2 -0.6
Osteoarthritis (self-reported) 0.5 0.6 1.6 0.3 1.0 0.4 0.5 0.8 0.9 0.6 1.3 0.9
Medication: Aspirin 0.3 0.3 1.0 -0.7 0.2 0.3 0.8 1.0 -0.0 0.5 0.6 -0.1
Medication: Gliclazide 0.2 0.3 1.0 0.1 0.2 0.4 -0.0 -0.0 0.4 -0.8 1.0 0.5
Illnesses of father: None of the above (group 1) 0.6 0.7 4.1 -1.0 0.2 -0.3 0.5 -0.1 0.6 2.0 -0.8 -0.3
Smoking status: Current 1.0 1.5 5.4 2.0 -0.2 1.5 -0.1 -0.5 1.0 0.1 2.3 0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.6 1.2 2.8 1.3 -0.9 -0.7 -1.0 -0.3 -1.5 -0.1 -1.7 -1.1
Whole body water mass 2.4 14.0 29.6 -1.4 4.8 5.4 3.9 4.3 3.7 0.1 3.4 3.5
Leg predicted mass (right) 2.6 14.1 23.4 -2.1 4.8 4.7 4.2 4.4 3.8 0.7 3.5 3.6
Arm fat mass (left) 0.9 3.6 7.8 -1.8 1.9 1.0 2.8 2.4 1.4 2.7 1.2 0.5
Number of self-reported non-cancer illnesses 0.5 0.9 2.7 -0.8 0.2 0.4 1.0 0.7 1.2 0.8 1.6 1.0
Average weekly champagne plus white wine intake 0.4 0.5 2.5 -1.6 0.2 -1.1 0.4 -0.1 -0.3 -0.3 -0.7 -0.5
Miserableness 0.9 1.5 3.2 1.4 0.7 1.7 -0.1 0.1 1.2 -1.8 1.4 1.4
Guilty feelings 0.5 0.8 2.4 1.5 0.9 0.6 -0.0 0.5 0.7 -1.3 0.6 0.9
Wears glasses or contact lenses 0.8 0.9 1.8 -1.3 -0.9 -0.4 0.5 -0.6 -0.5 0.9 -1.4 -1.3
Ever taken oral contraceptive pill 1.5 1.6 3.9 2.0 -1.2 -1.3 -1.5 -1.4 -1.3 0.5 0.5 -1.0
Hearing aid user 0.2 0.3 0.6 -0.7 0.5 0.8 0.6 0.2 -0.0 -0.5 0.4 0.5
Mother’s age at death 0.4 0.5 0.9 0.9 0.4 0.9 0.3 0.2 0.9 -0.5 1.0 0.7
Financial situation satisfaction 1.1 1.3 2.6 1.3 -0.7 -0.9 -1.6 -1.4 -1.1 1.0 -1.0 -0.9
Tinnitus: Yes, now most or all of the time 1.0 1.2 4.3 2.1 -0.6 -0.9 -1.3 -0.7 -1.1 -0.9 0.9 -0.5
Commuting to job workplace: Public transport 0.4 0.4 1.5 -0.4 0.2 0.5 -0.4 0.3 0.9 -1.2 0.3 1.0
Eye problems/disorders: Glaucoma 1.2 1.4 3.2 -0.7 1.2 1.8 1.5 1.5 1.2 0.9 0.8 0.9
Medication: Blood pressure 0.1 0.2 0.5 -0.4 0.5 0.5 -0.1 0.5 0.1 0.7 -0.4 0.5
Pain type(s) experienced in last month: Hip pain 1.6 2.1 4.2 -1.4 1.4 1.2 1.2 1.6 2.0 -0.3 1.8 1.4
Supplements: Fish oil (including cod liver oil) 0.1 0.1 0.3 0.1 0.5 0.5 -0.0 -0.4 0.5 0.3 0.0 0.5
High cholesterol (Self-reported) 0.4 0.6 4.3 -0.7 0.1 -0.0 0.2 0.0 -0.0 2.1 -0.8 0.5
Medication: Bendroflumethiazide 0.2 0.3 1.5 -0.2 -0.3 -0.3 -0.0 -0.3 -0.1 1.2 -0.7 -0.0
Medication: Paracetamol 1.2 1.9 3.6 -1.0 1.2 1.8 1.4 0.9 1.6 -0.5 1.3 1.9
Medication: Lisinopril 0.1 0.2 0.6 -0.1 0.4 -0.1 -0.3 0.4 -0.6 -0.8 -0.4 -0.1
Medication: Atorvastatin 0.5 0.6 1.5 0.9 -0.7 -0.6 -0.8 -1.2 -0.8 -0.7 -0.3 -0.8
Illnesses of father: High blood pressure 0.1 0.2 0.5 -0.7 -0.1 0.4 -0.2 0.4 -0.4 -0.6 0.2 -0.3
Alcohol drinker status: Never 0.5 0.6 2.1 0.5 1.5 0.3 0.6 1.0 0.6 -0.8 0.4 0.6
Ever smoked 0.5 0.9 2.3 1.3 -0.8 -0.9 -0.8 -1.5 -0.1 1.4 0.0 -0.0
Basal metabolic rate 2.4 13.3 25.2 -1.6 4.7 5.0 4.0 4.4 3.6 0.5 3.2 3.3
Leg fat percentage (left) 0.6 2.0 10.0 -0.6 0.3 -1.3 1.4 1.4 -0.2 3.2 -1.0 -0.9
Arm fat-free mass (left) 2.3 11.4 24.8 -0.6 4.5 5.0 3.4 4.0 3.4 0.2 2.8 3.2
Number of operations (self-reported) 0.2 0.3 1.2 -0.2 0.6 -0.2 1.1 0.5 0.1 0.9 -0.1 0.3
Average weekly beer plus cider intake 3.7 5.4 8.6 0.9 -2.9 -2.3 -2.8 -2.2 -1.7 2.6 -2.2 -2.6
Irritability 0.7 1.2 2.7 -1.1 1.2 0.8 1.0 1.2 1.5 -0.2 0.5 1.6
Risk taking 0.4 0.6 1.3 1.2 -0.9 -0.6 -1.1 -0.6 -0.6 0.6 -1.1 -0.2
Ever had prostate specific antigen (PSA) test 0.6 0.7 4.0 -0.3 0.9 -0.5 0.6 0.6 0.5 2.0 0.5 0.4
Fractured/broken bones in last 5 years 0.7 0.9 2.2 1.5 -0.6 -0.4 -1.3 -0.5 -1.0 -1.1 -0.3 -1.0
Age started oral contraceptive pill 0.3 0.4 2.6 0.2 -0.4 0.1 -0.3 -0.7 0.3 -1.6 -0.2 -0.0
Diastolic blood pressure, automated reading 0.3 0.9 2.8 -1.4 0.9 -0.5 1.7 1.4 0.3 0.3 -0.1 0.5
Ever depressed for a whole week 0.3 0.3 1.0 0.7 0.0 0.3 -0.8 -1.0 -0.6 -0.0 -0.5 -0.3
Unable to work because of sickness or disability 0.8 1.1 2.8 1.5 -0.9 -0.3 -1.7 -0.5 -1.4 -0.2 -1.0 -0.6
Commuting to job workplace: Cycle 1.6 1.9 4.6 0.6 -1.2 -2.1 -1.2 -1.1 -1.8 -0.1 -1.6 -1.6
Myopia 1.6 2.3 11.2 -1.1 0.8 1.7 0.9 1.1 1.2 3.3 0.9 0.6
Vascular/heart problems diagnosed by doctor 0.1 0.3 1.4 0.8 0.3 -0.0 0.2 -0.1 0.1 -1.2 0.7 0.1
Cholesterol lowering medication 1.2 1.7 6.6 0.3 -1.0 -0.8 -0.9 -0.1 -1.1 2.6 -2.1 -1.0
Medication: Omeprazole (e.g. Zanprol) 0.4 0.4 1.7 0.5 0.8 0.6 -0.5 0.2 -0.4 -0.7 1.3 0.3
Pain experienced in last month 1.8 3.0 7.4 0.2 -2.0 -1.6 -1.3 -1.7 -1.9 0.6 -2.7 -2.1
Supplements: Calcium 0.2 0.3 1.0 0.6 0.2 -1.0 -0.3 -0.5 0.2 0.7 -0.1 -0.1
Basal cell carcinoma (self-reported) 0.3 0.3 1.0 -0.6 0.9 -0.1 1.0 0.2 0.2 0.5 0.5 0.6
Heart attack/myocardial infarction (self-reported) 0.1 0.1 0.4 -0.2 -0.0 -0.6 0.1 -0.1 0.0 0.0 -0.4 0.1
Deep venous thrombosis (DVT) (self-reported) 0.6 0.7 3.0 1.4 -0.1 0.1 -0.6 0.0 -0.8 -1.7 0.5 0.2
Heart disease (siblings) 1.0 1.3 2.8 1.7 -0.9 -1.4 -1.5 -1.2 -1.0 -0.1 -0.6 -0.7
Alcohol drinker status: Previous 1.0 1.2 1.7 -1.1 1.3 0.8 1.2 0.6 1.3 -1.3 0.7 1.3
Pack years of smoking 0.9 1.3 4.3 0.3 0.8 1.3 0.5 0.7 1.5 0.3 2.1 1.4
Impedance of whole body 0.8 4.0 7.3 1.1 -2.7 -2.1 -2.0 -2.6 -2.2 -0.0 -1.9 -2.0
Leg fat mass (left) 0.5 2.1 8.0 -0.9 1.3 0.1 2.1 1.9 0.7 2.8 0.3 -0.0
Arm predicted mass (left) 2.3 11.8 24.7 -1.0 4.5 5.0 3.7 4.2 3.4 0.2 2.9 3.1