TWAS hub - KLB

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.5280	0.0430	0.00000	0.467	0.456	0.514	0.514	0.511	1.0e-63	1.1e-61	9.6e-73	1.2e-72	4.9e-72
2	METSIM	Adipose	0.0775	0.0279	0.00045	0.026	0.015	0.027	0.016	0.036	7.7e-05	2.0e-03	5.3e-05	1.6e-03	3.7e-06
3	NTR	Blood	0.0291	0.0121	0.00140	0.014	0.011	0.022	0.013	0.020	2.3e-05	1.2e-04	6.9e-08	3.1e-05	3.5e-07
4	TCGA	Kidney Renal Clear Cell Carcinoma	0.0290	0.0161	0.00800	0.002	0.005	0.002	NA	0.005	1.8e-01	7.1e-02	1.6e-01	NA	9.0e-02
5	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1050	0.0510	0.00056	0.068	0.048	0.005	NA	0.044	9.3e-05	9.8e-04	1.6e-01	NA	1.6e-03
6	TCGA	Brain Lower Grade Glioma	0.3411	0.0592	0.00000	0.344	0.342	0.361	NA	0.357	1.9e-40	4.0e-40	7.7e-43	NA	2.8e-42
7	TCGA	Liver Hepatocellular Carcinoma	0.1060	0.0440	0.00038	0.070	0.042	0.014	NA	0.045	3.2e-04	4.4e-03	7.0e-02	NA	3.4e-03
8	TCGA	Thyroid Carcinoma	0.0590	0.0280	0.00086	0.036	0.020	0.038	NA	0.047	1.9e-04	4.2e-03	1.1e-04	NA	2.3e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Alcohol intake frequency.	7.6	17.7	76.5	1.9	2.5	-0.9	6.3	8.7	0.8	-3.5	1.4
Crohns Disease (2012)	4.5	7.3	13.6	-3.7	1.9	0.3	-2.1	-1.7	-3.3	3.2	-3.6
Ever taken oral contraceptive pill	4.2	4.7	9.9	2.8	-0.1	1.5	1.5	0.7	2.8	-2.6	3.1
Crohns Disease (2017)	3.5	7.7	14.3	-3.8	1.3	0.3	-2.1	-1.7	-3.4	3.7	-3.6
Alcohol intake versus 10 years previously	3.4	5.1	18.7	1.5	2.3	0.0	2.8	4.3	0.8	-2.1	1.2
Average weekly beer plus cider intake	3.2	4.6	15.7	0.6	-0.4	0.5	-3.9	-4.0	1.3	1.3	1.1
Ever highly irritable/argumentative for 2 days	3.1	3.8	7.1	2.6	-0.4	2.1	0.9	1.1	2.2	-2.7	2.2
Irritable Bowel Disease (IBD)	2.9	6.9	13.8	-3.5	1.0	-0.3	-1.9	-2.2	-3.0	3.7	-3.2
Medication: Ibuprofen	2.9	3.5	10.1	1.4	0.1	0.3	3.2	2.8	0.8	-2.4	1.3
Hand grip strength (right)	2.8	7.6	19.1	2.6	0.1	1.2	4.0	4.4	1.5	-3.6	1.8
Reason for reducing amount of alcohol drunk: Health precaution	2.7	3.1	16.8	-0.2	-0.6	0.2	-2.5	-4.1	0.4	1.1	0.2
Ever had prostate specific antigen (PSA) test	2.5	2.9	5.4	2.3	0.5	-0.0	1.4	1.4	2.3	-1.9	2.3
Qualifications: CSEs or equivalent	2.4	3.2	7.0	-2.4	-1.5	-0.4	-1.4	-0.8	-2.7	1.3	-2.4
Hair/balding pattern: Pattern 2	2.4	3.1	5.5	-2.2	-0.1	-0.9	-2.1	-1.8	-2.1	1.3	-2.4
Noisy workplace	2.4	3.0	7.2	2.0	-0.8	2.7	0.2	0.1	2.3	-1.7	1.9
Seen doctor (GP) for nerves, anxiety, tension or depression	2.4	3.7	7.3	-2.1	-0.3	-2.2	1.6	2.3	-2.7	0.2	-2.2
Tinnitus: Yes, now most or all of the time	2.4	2.8	4.8	2.2	1.4	2.1	0.7	0.8	1.9	-1.9	1.7
Myopia	2.4	3.5	8.2	2.6	-0.5	1.7	0.3	0.3	2.6	-1.6	2.9
Gout (self-reported)	2.3	3.1	10.3	-0.5	-1.5	1.0	-3.2	-3.0	-0.1	1.5	-0.3
Medication: Allopurinol	2.3	3.0	10.3	-0.7	-1.4	0.2	-2.9	-3.2	-0.4	1.5	-0.5
Hand grip strength (left)	2.2	5.7	10.6	2.5	0.8	1.4	3.2	3.2	1.7	-3.2	1.8
Mouth/teeth dental problems: Dentures	2.2	3.7	7.5	-2.6	0.5	-0.9	-1.3	-1.3	-2.4	2.7	-2.2
Health satisfaction	2.2	2.9	10.0	1.2	-3.2	0.4	-1.3	-2.2	1.6	-0.3	1.4
Breast cancer (self-reported)	2.2	2.6	3.9	-2.0	-0.6	-1.0	-1.9	-1.4	-1.7	1.9	-1.8
Average weekly champagne plus white wine intake	2.2	3.0	6.3	-1.6	-0.5	-2.4	-2.0	-2.5	-1.4	1.3	-1.3
Ovarian Cancer	2.1	2.8	4.4	-2.1	-1.9	-1.9	-1.1	-0.6	-1.6	1.3	-2.0
Had other major operations	2.1	2.6	6.9	-1.4	-0.1	-1.5	-2.4	-2.6	-0.9	1.5	-1.1
Comparative body size at age 10	2.1	5.7	9.1	3.0	1.4	2.2	1.8	2.0	2.7	-2.7	2.8
Average weekly red wine intake	2.1	3.1	12.4	-1.3	-3.5	-0.8	-1.3	-2.0	-0.9	1.4	-1.3
Coronary Artery Disease (CAD)	2.0	2.4	4.8	-2.2	-0.1	-0.4	-1.2	-0.5	-1.9	2.1	-2.2
Smoking Status	2.0	4.9	9.0	3.0	0.1	2.8	0.4	1.4	2.7	-2.4	2.6
Number of incorrect matches in round	2.0	3.4	6.1	1.8	2.5	1.6	-2.0	-0.0	2.4	0.5	2.2
Medication: Ibuprofen (e.g. Nurofen)	2.0	2.5	5.5	1.5	0.2	-0.3	2.3	2.1	1.1	-2.2	1.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.0	2.4	7.3	1.6	0.1	0.6	1.7	1.8	1.1	-2.7	1.3
LDL Cholesterol	1.9	3.0	7.7	-1.9	-0.2	0.5	-1.6	-2.6	-1.2	2.8	-1.4
Medication: Metformin	1.9	2.7	5.5	1.9	0.1	1.4	1.5	1.5	1.6	-2.3	1.9
Illnesses of mother	1.9	2.4	7.4	-0.4	2.2	-1.9	2.7	1.3	-0.6	-0.9	-0.3
Medication: Blood pressure	1.9	3.3	6.2	2.1	-0.6	0.9	2.5	0.3	2.3	-2.2	2.1
Rheumatoid Arthritis	1.8	2.5	9.1	-1.6	-2.1	-3.0	-0.4	-0.0	-1.1	1.0	-1.2
Intelligence (Savage-Jansen 2018)	1.7	5.2	14.7	-1.0	0.7	-2.8	3.1	3.8	-1.8	-1.6	-1.4
Verbal and Numeric Reasoning (VNR)	1.7	4.0	10.3	-1.0	0.7	-2.1	3.1	3.2	-1.7	-1.3	-1.4
Had major operations	1.7	2.0	6.2	0.6	-1.1	0.6	2.5	2.5	0.3	-1.3	0.4
Ever had hysterectomy (womb removed)	1.6	1.8	3.3	-1.6	0.6	-0.9	-1.1	0.2	-1.6	1.7	-1.8
Heel bone mineral density (BMD) T-score, automated (right)	1.6	3.7	9.6	-2.7	-1.6	-1.0	0.1	-1.2	-3.1	1.3	-2.5
Prospective memory result	1.6	2.0	5.5	1.5	1.0	2.3	-0.8	0.5	1.6	-1.2	1.6
Angina (self-reported)	1.6	2.2	10.4	-0.5	-0.7	1.3	-3.2	-1.5	-0.1	1.5	-0.4
Qualifications: NVQ or HND or HNC or equivalent	1.6	1.9	4.5	-0.1	-1.0	1.9	-2.1	-2.1	0.3	1.2	0.3
Illnesses of siblings: Diabetes	1.6	1.9	3.6	1.7	0.5	1.8	-1.1	-0.3	1.9	-1.0	1.7
Eye problems/disorders: Cataract	1.6	1.8	10.3	0.7	-3.2	0.4	-0.8	-1.1	0.8	0.2	1.0
Current tobacco smoking	1.5	2.5	4.9	2.2	-0.3	2.0	-0.2	1.1	1.9	-1.4	2.1
Seen a psychiatrist for nerves, anxiety, tension or depression	1.5	1.9	4.6	-1.8	0.3	-1.1	-1.2	0.0	-2.1	1.1	-1.9
Mouth/teeth dental problems: Loose teeth	1.5	1.8	4.3	1.8	0.3	1.4	-0.0	-0.1	1.9	-1.1	2.1
Smoking status: Current	1.5	2.3	4.8	2.1	-0.1	2.2	-0.4	0.8	1.8	-1.2	1.9
Financial situation satisfaction	1.5	1.8	7.1	-0.0	-2.7	0.1	-1.4	-2.2	0.4	0.7	0.4
Schizophrenia vs Biploar Disorder	1.4	1.8	8.3	0.8	1.6	2.9	0.0	-1.0	0.9	-0.0	0.9
Angina	1.4	1.9	8.5	-0.4	-0.6	1.5	-2.9	-1.4	-0.1	1.2	-0.3
Chronic bronchitis/emphysema (father)	1.4	1.7	3.9	1.5	-0.3	0.3	1.3	1.2	1.4	-2.0	1.4
Ever unenthusiastic/disinterested for a whole week	1.4	1.7	5.6	1.0	-0.7	-0.2	2.4	1.2	0.5	-1.9	0.8
Financial difficulties in last 2 years	1.4	1.9	4.0	1.4	-1.3	2.0	-0.0	-1.2	1.6	-0.4	2.0
Hayfever/allergic rhinitis (self-reported)	1.4	1.8	4.1	-1.2	-2.0	-1.0	-1.5	-0.5	-1.3	1.3	-1.4
Alzheimer’s Disease (in mother)	1.3	1.5	5.0	-0.9	-0.6	-0.4	-2.2	-1.7	-0.6	1.5	-0.6
Mean Putamen Volume	1.3	1.5	3.7	1.2	1.2	0.6	1.3	1.9	0.8	-1.3	0.8
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	9.7	-0.0	1.3	3.1	-0.1	-0.3	-0.3	0.3	-0.3
Depression (self-reported)	1.3	1.6	4.2	0.3	0.4	0.9	2.0	2.0	-0.3	-1.8	0.4
Shortness of breath walking on level ground	1.3	1.6	5.8	0.0	-1.5	0.8	-1.8	-2.4	0.5	0.6	0.5
Medication: Seretide 50 evohaler	1.3	1.5	3.8	1.3	-1.8	1.1	0.5	0.2	1.0	-2.0	0.9
Mean time to correctly identify matches	1.3	2.4	5.1	2.1	0.4	1.1	0.8	0.5	2.2	-1.8	2.3
Leg pain on walking	1.3	1.6	4.6	1.0	0.0	0.5	1.9	2.1	0.6	-1.6	0.7
Cholesterol lowering medication	1.3	2.0	4.3	-1.4	0.2	0.1	-1.9	-1.9	-1.0	2.1	-1.1
Bipolar Disorder (2011)	1.2	1.2	2.4	-0.9	0.8	-1.6	0.8	1.4	-1.3	0.0	-1.2
Fasting Glucose	1.2	1.5	2.9	-1.2	-0.4	0.5	-1.7	-1.5	-1.2	1.4	-1.2
Chronotype (morning person)	1.2	2.7	6.0	-2.4	-0.2	-1.4	1.0	0.4	-2.5	1.3	-2.2
Impedance of leg (right)	1.2	5.8	11.2	-2.5	-2.2	0.7	-3.0	-3.4	-2.0	2.1	-2.5
Relative age voice broke	1.2	1.8	4.5	-1.1	1.7	-0.0	-1.6	-1.6	-0.4	2.1	-0.7
Worrier / anxious feelings	1.2	2.2	4.3	-2.0	0.2	-1.6	0.8	1.1	-2.1	1.5	-1.8
Loud music exposure frequency	1.2	1.4	4.3	-0.0	0.3	-2.1	1.4	1.4	-0.4	-1.4	-0.4
Long-standing illness, disability or infirmity	1.2	1.9	5.7	1.1	-0.0	-0.8	1.9	1.8	0.6	-2.4	0.7
Mouth/teeth dental problems: Mouth ulcers	1.2	1.8	5.8	-1.1	0.8	-2.4	1.2	1.5	-1.4	-0.2	-1.2
Breast Cancer	1.1	2.6	6.1	2.0	-0.3	1.2	-0.5	-0.8	2.5	-1.6	2.4
Prostate Cancer	1.1	1.6	4.1	-1.0	-0.2	-0.9	2.0	1.9	-1.3	0.3	-1.3
Sensitivity / hurt feelings	1.1	1.9	5.0	-1.9	-0.2	-0.7	0.3	0.7	-2.2	1.4	-1.8
Heel bone mineral density (BMD) T-score, automated (left)	1.1	2.6	5.6	-1.9	-2.3	-0.8	0.4	-0.7	-2.4	0.7	-2.1
Tinnitus: Yes, but not now, but have in the past	1.1	1.2	4.0	0.9	-1.4	2.0	-0.1	-0.8	1.0	-0.3	0.9
Impedance of leg (left)	1.1	5.4	10.8	-2.4	-1.7	1.2	-2.7	-3.3	-2.1	2.1	-2.5
Had menopause	1.1	1.4	2.7	-1.7	-0.0	-1.5	0.4	-0.1	-1.6	1.1	-1.4
Fluid intelligence score	1.1	2.2	5.1	-1.1	0.2	-2.0	2.2	1.8	-1.6	-0.3	-1.3
Happiness	1.1	1.4	4.4	-0.2	-2.1	-1.7	1.8	0.6	-0.4	-0.1	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.3	4.9	1.1	-0.2	0.4	0.8	2.2	0.7	-1.7	0.5
Pulse rate, automated reading	1.1	3.5	5.9	-2.4	-1.7	-1.0	-1.3	-1.8	-2.0	2.0	-2.3
Comparative height size at age 10	1.1	5.8	18.0	0.8	0.4	-1.2	4.2	4.1	-0.3	-3.1	0.4
Chest pain or discomfort	1.1	1.6	2.5	1.4	-1.3	1.6	-1.4	-0.8	1.4	-0.4	1.5
Age at last live birth	1.1	1.5	3.8	-1.4	0.3	-1.4	0.9	0.6	-1.7	0.8	-2.0
Supplements: Vitamin C	1.1	1.4	2.6	-1.5	0.9	-1.3	-0.0	0.4	-1.4	1.1	-1.6
Neuroticism (Nagel 2018)	1.0	2.3	7.0	-1.7	0.3	-0.7	0.2	1.8	-2.6	0.4	-2.2
Ulcerative Colitis	1.0	1.4	3.4	-1.0	1.4	0.2	-1.2	-1.4	-0.8	1.8	-0.8
Neuroticism	1.0	2.3	5.5	-1.1	-0.5	-1.3	1.2	2.4	-2.2	-0.7	-1.7
Other serious medical condition/disability diagnosed by doctor	1.0	1.3	3.4	1.2	-0.9	0.1	1.8	0.4	0.9	-1.3	1.2
Pack years adult smoking proportion	1.0	1.5	3.0	1.3	-0.2	1.6	0.8	1.2	0.9	-1.7	1.4
Supplements: Glucosamine	1.0	1.3	6.3	-0.8	-0.8	-2.5	1.2	0.6	-0.7	0.5	-0.4
High blood pressure (mother)	1.0	1.5	6.8	0.5	-2.6	1.5	-1.4	-0.2	0.4	-0.2	0.2
Mouth/teeth dental problems	1.0	1.5	3.1	1.8	0.4	1.6	-0.2	0.4	1.6	-1.2	1.3
Pulse wave reflection index	1.0	1.2	3.6	1.2	0.2	1.9	0.2	-0.5	1.3	-0.6	1.4
Medication: Aspirin	1.0	1.3	2.1	-1.4	-0.6	-1.0	-1.3	-0.1	-1.3	1.5	-1.3
Age started oral contraceptive pill	1.0	1.2	2.7	-1.4	0.5	-1.2	0.4	0.3	-1.6	1.0	-1.4
Triglycerides	0.9	1.5	2.8	1.7	0.7	1.6	0.3	0.9	1.2	-1.6	1.2
Diabetes (mother)	0.9	1.1	1.6	1.2	-1.3	0.6	1.3	0.9	0.8	-1.2	1.1
Medication: Simvastatin	0.9	1.3	3.1	-1.0	1.8	1.0	-1.3	-0.6	-0.9	1.4	-0.8
Qualifications: A levels/AS levels or equivalent	0.9	2.0	9.1	0.1	0.7	-1.4	3.0	1.7	0.1	-1.2	-0.1
Exposure to tobacco smoke at home	0.9	1.1	2.8	-1.2	-0.5	-0.3	-1.7	0.0	-1.2	1.0	-1.1
Medication for cholesterol, blood pressure or diabetes	0.9	1.5	4.5	-1.1	0.8	-0.7	-2.1	-0.6	-1.2	1.3	-1.3
Leg fat percentage (right)	0.9	3.3	9.3	-1.8	0.3	-0.4	-2.6	-3.0	-1.1	2.1	-1.0
Worry too long after embarrassment	0.9	1.5	6.0	0.9	-0.1	0.9	1.5	2.4	0.2	-1.2	0.7
Family relationship satisfaction	0.9	1.1	3.1	1.3	-0.7	0.3	0.2	-1.3	1.4	-0.4	1.8
Knee pain experienced in last month	0.9	1.4	2.6	1.4	0.9	1.6	-1.1	0.9	1.2	-0.4	1.4
Friendships satisfaction	0.9	1.1	2.6	1.2	-0.2	0.7	0.6	-0.6	1.2	-1.3	1.6
Medication: Aspirin	0.9	1.1	1.7	-1.2	-0.9	-1.3	-0.7	0.1	-1.2	1.1	-1.3
Illnesses of father: None of the above (group 1)	0.9	1.1	3.5	-0.2	1.9	-0.4	-1.1	-1.2	0.2	1.7	0.2
Commuting to job workplace: Cycle	0.9	1.1	4.3	-0.6	2.1	-0.9	0.3	-1.1	-0.2	1.1	-0.5
Bipolar Disorder (2018)	0.8	1.3	4.0	0.6	0.1	-1.2	1.9	2.0	0.1	-0.9	0.4
Depression (Nagel 2018)	0.8	1.2	2.7	-1.0	-0.9	-0.6	-0.0	1.6	-1.5	0.7	-1.2
Alzheimer’s Disease (including proxy)	0.8	1.1	3.4	-0.5	-0.4	-1.0	-1.8	-1.8	0.0	1.0	-0.1
Age at First Birth	0.8	1.2	5.0	-0.3	0.4	-2.2	2.1	0.3	0.1	-0.2	0.1
Blood Red Count	0.8	8.0	34.0	-0.1	-0.9	-0.4	5.8	5.0	-1.2	-1.2	-0.5
Medication: Co-codamol	0.8	0.9	4.3	0.6	2.1	1.1	0.3	0.6	0.3	-0.8	0.6
Serious illness, injury or assault to yourself	0.8	1.0	2.5	0.2	-1.6	-1.1	-0.4	-1.6	0.4	-1.1	0.2
Alcohol usually taken with meals	0.8	1.2	4.4	-0.7	-2.1	-1.9	0.8	0.0	-0.4	0.3	-0.7
Hearing difficulty/problems with background noise	0.8	1.2	2.6	1.4	0.9	0.4	0.5	0.7	1.2	-1.6	1.5
Peak expiratory flow (PEF)	0.8	1.8	4.1	1.4	0.3	0.9	1.4	2.0	1.2	-1.6	1.1
Medication: Amlodipine	0.8	1.1	2.5	0.8	0.8	-0.4	1.3	1.5	0.6	-1.6	0.8
Number of full brothers	0.8	1.0	2.3	1.3	0.1	0.1	-0.8	-1.1	1.5	-0.5	1.5
Qualifications: College or University degree	0.8	2.5	8.2	-0.5	0.2	-2.2	2.9	2.3	-0.5	-0.3	-0.8
Medication for pain relief, constipation, heartburn	0.8	1.4	5.2	-0.9	0.8	-0.5	-1.2	-2.3	-0.4	1.6	-0.6
Overall health rating	0.8	1.8	5.7	1.0	-0.5	1.7	-2.4	-1.5	1.0	-0.4	1.0
Mood swings	0.8	1.4	3.3	-0.8	0.0	1.1	0.7	1.8	-1.8	-0.1	-1.4
Osteoporosis (self-reported)	0.8	1.0	2.8	1.0	1.1	0.3	1.0	0.7	0.9	-1.7	0.8
Guilty feelings	0.8	1.2	5.8	0.6	0.5	0.3	1.5	2.4	-0.2	-0.9	0.1
Medication: Paracetamol	0.8	1.2	2.6	-1.1	-0.3	-1.3	0.0	1.3	-1.4	0.7	-1.6
Leg fat percentage (left)	0.8	3.0	8.4	-1.7	0.6	-0.1	-2.4	-2.9	-1.2	2.1	-0.9
Supplements: Calcium	0.8	0.9	2.2	1.2	1.1	0.5	-0.3	-0.5	1.4	0.1	1.5
Pack years of smoking	0.8	1.2	2.0	1.2	0.2	1.4	0.7	1.1	0.8	-1.4	1.3
Ulcerative Colitis (UC)	0.7	1.2	2.6	-1.4	0.7	-0.4	-0.3	-1.5	-1.1	1.6	-1.1
Reaction Time	0.7	1.3	2.5	1.5	-0.4	1.0	0.2	0.3	1.6	-1.3	1.5
Neuroticism (2016)	0.7	1.1	2.8	-1.0	-0.6	-0.2	-0.9	0.3	-1.7	1.0	-1.5
Blood Platelet Count	0.7	8.1	18.1	-3.8	1.5	-1.3	-1.6	-0.7	-4.0	3.0	-4.3
Allergy or Eczema	0.7	1.9	3.4	-1.4	-1.8	-1.4	-0.7	0.4	-1.7	1.4	-1.5
Type 2 Diabetes (T2D) (2018)	0.7	1.4	2.5	1.6	-1.1	1.0	0.5	0.3	1.3	-1.4	1.6
Average weekly spirits intake	0.7	0.9	4.0	-0.6	0.4	-2.0	0.7	1.3	-0.1	0.6	-0.4
Relative age of first facial hair	0.7	1.4	3.5	-0.6	1.4	-0.1	-1.6	-1.9	0.0	1.6	-0.4
Medication: Ramipril	0.7	0.9	1.4	1.0	-0.6	1.1	0.2	-1.2	1.1	-1.1	1.1
Neuroticism score	0.7	1.5	5.8	0.1	-1.2	0.2	1.7	2.4	-0.8	-1.1	-0.2
Trunk fat-free mass	0.7	4.0	16.7	0.7	1.1	-0.1	3.2	4.1	-0.4	-1.8	0.3
Time employed in main current job	0.7	0.8	3.6	0.5	-0.5	-1.9	0.4	1.1	0.6	-0.7	0.5
Father’s age at death	0.7	0.9	1.9	-0.7	-0.7	-0.8	0.4	1.4	-1.2	0.3	-1.3
Trunk predicted mass	0.7	4.2	17.6	0.8	1.0	-0.0	3.3	4.2	-0.4	-1.9	0.3
Birth weight of first child	0.7	1.3	3.2	-1.3	-0.5	-0.3	-0.7	1.2	-1.8	0.7	-1.6
Chronic bronchitis/emphysema (mother)	0.7	0.8	4.2	-0.5	0.3	-0.1	-2.0	-1.3	-0.2	0.2	-0.5
Number of children fathered	0.7	0.8	2.5	-0.6	0.8	0.2	-1.0	-1.6	-0.4	1.1	-0.7
Emphysema/chronic bronchitis	0.7	0.8	2.7	0.8	-0.7	0.2	1.2	0.6	0.5	-1.6	0.7
Handedness (chirality/laterality): Left-handed	0.7	0.8	4.1	-0.5	-2.0	-0.5	-0.4	-0.6	-0.6	0.9	-0.5
Medication for cholesterol	0.7	1.0	3.7	0.1	-0.4	-0.4	1.3	1.9	-0.3	-1.5	-0.0
Leg predicted mass (right)	0.7	3.5	10.8	1.2	1.3	-0.9	2.8	3.3	0.4	-2.0	1.1
Hearing aid user	0.7	0.8	1.8	-1.2	-0.4	-0.8	0.2	-0.2	-1.4	0.6	-1.3
Medication: Bendroflumethiazide	0.7	1.0	7.2	-0.3	-2.7	0.1	0.1	-0.9	-0.2	0.1	-0.3
Medication: Atorvastatin	0.7	0.9	5.9	-0.1	-2.4	-0.8	0.7	0.2	-0.0	-0.3	0.0
Risk taking	0.7	1.0	4.6	-0.7	2.1	0.0	0.3	0.6	-0.9	1.0	-0.7
Diastolic blood pressure, automated reading	0.7	2.3	4.7	-1.5	-2.2	-1.2	-0.6	-2.0	-1.0	1.8	-1.1
Ever depressed for a whole week	0.7	0.9	1.9	0.8	1.1	-0.1	1.4	0.9	0.5	-1.4	0.8
Medication: Omeprazole (e.g. Zanprol)	0.7	0.9	3.2	0.9	-0.5	1.1	0.1	0.8	0.6	-1.8	0.7
Bipolar Disorder or Schizophrenia	0.6	1.5	3.1	1.6	0.2	0.3	1.4	1.2	1.1	-1.5	1.8
Depressed Affect (Nagel 2018)	0.6	1.2	3.6	-0.9	0.2	-0.0	-0.3	1.7	-1.9	-0.1	-1.5
Schizophrenia (2018)	0.6	1.3	3.6	1.6	0.1	1.3	0.3	-0.1	1.3	-1.1	1.9
HDL Cholesterol	0.6	1.1	2.1	0.8	-0.9	-1.5	-1.1	-1.1	1.1	-0.4	1.0
Eye problems/disorders: Diabetes related eye disease	0.6	0.7	1.8	-0.8	0.1	0.6	-1.3	-0.6	-0.9	0.9	-0.9
Diabetes (father)	0.6	0.7	4.6	0.4	-2.2	0.2	0.2	0.8	0.2	-0.2	0.1
Leg fat-free mass (left)	0.6	3.1	9.1	1.3	1.1	-0.9	2.6	3.0	0.6	-1.9	1.2
Hayfever, allergic rhinitis or eczema	0.6	1.2	6.4	-0.5	-2.5	-0.5	0.1	1.1	-0.8	0.3	-0.8
Leg predicted mass (left)	0.6	3.0	9.0	1.2	1.2	-0.9	2.5	3.0	0.5	-1.9	1.2
Past tobacco smoking	0.6	1.1	2.1	-1.2	-0.8	-1.1	0.6	0.6	-1.5	0.6	-1.3
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	2.0	1.0	-1.4	1.3	-0.0	1.1	0.6	-0.7	0.9
Illnesses of siblings	0.6	0.8	2.6	-0.7	1.0	0.1	1.6	1.0	-0.8	0.6	-0.7
Falls in the last year	0.6	0.8	2.0	-0.1	1.4	0.5	0.9	1.4	-0.7	-0.8	-0.4
Hair/balding pattern: Pattern 3	0.6	0.9	3.3	0.7	-1.0	1.8	0.5	-0.2	1.1	0.3	1.0
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.6	2.2	-0.6	1.5	-0.6	0.7	0.1	-0.9	-0.2	-0.9
Length of working week for main job	0.6	0.7	3.4	0.6	0.7	1.9	0.4	0.6	0.4	-0.5	0.3
Hair/balding pattern: Pattern 4	0.6	1.5	5.9	1.1	0.8	-2.4	0.1	1.7	0.8	-0.6	0.9
Headache pain in last month	0.6	1.1	4.1	1.1	0.2	0.5	1.0	2.0	0.4	-1.1	0.6
Body fat percentage	0.6	2.2	7.0	-1.5	0.2	-0.9	-1.9	-2.6	-0.9	1.6	-0.7
Wheeze or whistling in the chest in last year	0.6	1.1	2.1	1.1	1.4	1.1	-0.5	0.6	1.1	-0.8	1.2
Eye problems/disorders: None of the above	0.6	0.7	4.9	-0.2	2.2	0.2	0.2	-0.3	-0.0	-0.4	-0.3
Number of full sisters	0.6	0.7	2.2	-0.4	0.3	0.8	-1.5	-0.9	-0.5	1.2	-0.6
Whole body fat-free mass	0.6	3.6	13.9	0.9	1.2	-0.4	3.0	3.7	-0.1	-1.8	0.6
Leg fat-free mass (right)	0.6	3.5	10.6	1.2	1.3	-0.8	2.8	3.3	0.4	-2.0	1.1
Ever had bowel cancer screening	0.6	0.7	3.5	0.3	1.9	0.8	0.8	0.8	0.0	-0.3	0.0
Diabetes diagnosed by doctor	0.6	1.0	2.3	1.4	-0.3	0.8	0.0	0.0	1.4	-1.0	1.5
Whole body water mass	0.6	3.7	14.3	0.8	1.2	-0.4	3.0	3.8	-0.1	-1.8	0.6
Miserableness	0.6	1.0	5.7	0.1	0.2	0.6	0.5	2.4	-0.8	-1.0	-0.3
Commuting to job workplace: Public transport	0.6	0.7	3.5	-0.3	-0.2	-0.5	0.8	1.9	-0.6	0.3	-0.6
Alcohol drinker status: Never	0.6	0.7	2.3	0.4	0.9	-0.2	1.0	1.5	-0.1	-1.2	0.2
Ever smoked	0.6	1.1	2.2	1.2	1.3	0.7	-0.3	-0.5	1.5	-0.5	1.4
Pain experienced in last month	0.6	1.0	2.3	-1.5	-1.0	-0.9	0.4	-0.6	-1.1	1.0	-1.1
Blood Eosinophil Count	0.5	4.0	9.1	2.0	-2.0	-3.0	0.7	1.1	1.8	-2.3	2.0
Height	0.5	10.5	37.5	-1.3	2.2	-1.3	4.0	6.1	-3.5	-1.8	-2.6
Systolic Blood Pressure	0.5	2.4	11.8	-0.4	-3.4	-0.4	0.5	-2.5	0.3	0.8	0.0
Vitamin and mineral supplements	0.5	0.7	2.3	0.5	-0.8	1.1	-1.5	-0.8	0.4	-0.1	0.4
Average weekly fortified wine intake	0.5	0.6	2.0	-0.4	0.6	0.2	0.7	1.4	-1.0	-0.2	-0.8
Maternal smoking around birth	0.5	0.8	2.1	-0.5	-0.8	1.3	-1.5	-0.1	-0.2	1.0	-0.4
Medication: Atenolol	0.5	0.6	2.8	-0.7	-0.7	-0.2	-0.7	-1.7	-0.5	0.4	-0.4
Medication: Levothyroxine sodium	0.5	0.8	4.6	-0.6	-0.4	-2.1	-0.6	-0.5	-0.3	0.6	-0.2
Medication: Lansoprazole	0.5	0.6	2.0	0.5	1.4	0.9	-0.7	0.5	0.4	-1.0	0.1
Standing height	0.5	5.4	20.3	0.5	0.4	-0.1	3.7	4.5	-0.9	-2.7	-0.3
Hypothyroidism/myxoedema (self-reported)	0.5	1.0	6.4	-0.4	-0.1	-2.5	-0.6	-0.8	-0.1	0.6	-0.1
High blood pressure (siblings)	0.5	0.8	1.4	0.8	-1.0	0.4	-1.2	-1.2	0.9	-0.7	0.7
Neck or shoulder pain in last month	0.5	0.6	3.1	0.6	-0.5	0.6	-1.7	-0.8	0.6	-0.1	0.4
Mineral and other dietary supplements	0.5	0.6	1.5	0.7	-0.9	0.8	0.6	1.2	0.5	-0.9	0.3
Supplements: Fish oil (including cod liver oil)	0.5	0.6	1.9	-0.7	0.4	-0.1	-1.0	-1.4	-0.7	0.9	-0.6
Basal metabolic rate	0.5	2.8	10.4	0.6	1.4	-0.6	2.6	3.2	-0.3	-1.6	0.4
Arm fat-free mass (left)	0.5	2.4	9.9	0.2	1.1	-0.1	2.3	3.1	-0.8	-1.2	-0.0
Irritability	0.5	0.8	1.7	-0.9	0.8	-0.9	0.0	1.2	-1.3	0.2	-1.0
Impedance of whole body	0.5	2.7	8.2	-1.4	-1.6	0.2	-2.1	-2.9	-1.0	1.2	-1.5
Arm predicted mass (left)	0.5	2.7	10.4	0.2	1.3	-0.3	2.6	3.2	-0.8	-1.3	-0.0
HbA1C	0.4	0.5	2.2	0.1	1.5	0.8	0.7	0.5	-0.3	-0.1	0.2
Primary Biliary Cirrhosis	0.4	0.6	1.3	-0.8	-0.7	-0.7	-0.4	-0.3	-1.1	0.5	-1.1
Schizophrenia (2014)	0.4	0.8	2.1	1.0	-0.1	1.5	0.1	-0.4	0.9	-0.6	1.3
Blood White Count	0.4	3.0	7.1	1.9	-2.7	2.3	0.0	-0.1	1.9	-1.2	1.7
Heel T-Score	0.4	3.4	12.5	-1.1	-3.5	-2.6	2.2	0.6	-1.1	-0.3	-0.7
Waist Hip Ratio (WHR)	0.4	2.0	5.5	-0.1	-2.0	-0.1	-2.2	-2.3	0.1	0.9	0.3
Frequency of depressed mood in last 2 weeks	0.4	0.5	2.0	-0.3	-0.9	0.0	0.6	1.4	-0.7	0.1	-0.4
Hearing difficulty/problems: Yes	0.4	0.5	1.7	0.6	0.2	-0.1	1.1	0.9	0.1	-1.3	0.5
Medication for hormone replacement therapy	0.4	0.5	1.2	0.6	-0.2	0.2	0.0	-1.0	1.0	0.0	1.1
Trunk fat percentage	0.4	1.6	4.7	-1.3	0.2	-1.1	-1.6	-2.2	-0.8	1.2	-0.5
Townsend deprivation index at recruitment	0.4	0.6	2.5	0.6	0.2	1.6	-0.8	-0.3	0.5	-0.3	0.8
Fed-up feelings	0.4	0.7	3.6	0.3	-1.9	0.7	-0.1	1.0	-0.4	-0.6	-0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	2.1	-0.0	-0.9	1.0	-0.2	1.4	-0.5	-0.1	0.0
Age when periods started (menarche)	0.4	1.1	2.7	1.0	-0.4	1.6	-0.9	-0.7	1.0	-0.6	1.4
Multivitamins +/- minerals	0.4	0.5	1.5	-0.5	1.2	-0.8	0.7	0.3	-0.4	0.8	-0.3
Stomach or abdominal pain in last month	0.4	0.5	1.3	0.6	0.8	1.1	-0.4	0.3	0.3	-0.9	0.4
Diverticular disease/diverticulitis (self-reported)	0.4	0.4	1.3	-0.3	0.6	1.1	0.1	0.6	-0.6	-0.5	-0.9
Qualifications: None of the above	0.4	0.8	2.9	0.4	0.1	1.6	-1.7	-0.5	0.1	-0.1	0.4
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	2.0	-0.7	-1.0	0.2	-0.7	0.3	-1.4	0.5	-0.9
Medication: Cholesterol lowering	0.4	0.6	1.4	-1.1	-0.9	-0.1	0.1	-0.1	-1.2	0.5	-1.1
Lung cancer (father)	0.4	0.5	2.7	0.1	-0.4	-1.6	0.5	0.7	0.0	0.2	0.1
Breastfed as a baby	0.4	0.5	2.3	-0.1	0.7	-0.8	1.5	0.1	0.1	0.5	0.0
Birth weight	0.4	0.9	2.6	1.1	1.6	0.2	0.1	1.2	0.6	-1.1	0.4
Arm fat-free mass (right)	0.4	2.2	8.8	0.2	1.2	-0.3	2.4	3.0	-0.7	-1.0	-0.1
Medication: Omeprazole	0.4	0.4	1.6	0.7	-0.1	0.7	-0.2	0.6	0.4	-1.3	0.5
Arm predicted mass (right)	0.4	2.3	9.7	0.2	0.8	-0.2	2.4	3.1	-0.7	-1.2	-0.0
Commuting to job workplace: Car/motor vehicle	0.4	0.4	1.4	0.6	-1.2	0.6	0.0	0.3	0.6	-0.8	0.4
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.0	0.6	0.5	-0.7	0.1	0.9	1.0	0.5	0.8
Illnesses of father: Heart disease	0.4	0.5	1.4	-0.9	0.1	0.7	0.2	0.5	-1.2	-0.4	-0.9
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.9	2.0	-0.6	-0.2	1.4	1.3	0.8	-1.0	0.1	-1.1
Commuting to job workplace: Walk	0.4	0.4	0.8	-0.6	0.4	-0.9	-0.3	-0.8	-0.5	0.9	-0.4
Eye problems/disorders: Glaucoma	0.4	0.4	1.0	-0.5	-0.6	-1.0	-0.5	-0.2	-0.5	1.0	-0.4
Pain type(s) experienced in last month: Hip pain	0.4	0.6	2.3	0.5	0.5	0.6	-1.5	0.0	0.5	-0.6	0.8
Medication: Lisinopril	0.4	0.6	1.2	0.9	1.1	0.1	1.0	0.4	0.9	-0.3	0.5
Fractured/broken bones in last 5 years	0.4	0.5	1.4	-0.3	1.2	0.3	-1.1	-0.4	-0.4	0.1	-0.8
Basal cell carcinoma (self-reported)	0.4	0.5	2.5	0.1	-0.7	-0.6	1.6	0.9	0.0	-0.3	0.1
Deep venous thrombosis (DVT) (self-reported)	0.4	0.6	1.3	0.6	1.1	1.0	0.7	1.1	0.2	-0.7	0.0
Alzheimer’s Disease (in father)	0.3	0.3	0.8	-0.7	-0.2	-0.9	-0.0	-0.3	-0.4	0.8	-0.5
Major Depression (MDD)	0.3	0.3	0.6	0.2	-0.6	-0.8	0.8	0.7	-0.0	-0.7	0.1
Lupus	0.3	0.5	1.5	-0.6	0.8	-0.1	-1.2	-0.7	-0.3	0.7	-0.3
Lung FEV1/FVC ratio	0.3	1.3	3.8	-0.4	1.2	-1.1	1.3	1.9	-1.0	-1.2	-0.4
Number of treatments/medications taken	0.3	0.5	1.8	-0.3	-0.4	-1.3	0.9	0.7	-0.5	-0.1	-0.4
Ever used hormone-replacement therapy (HRT)	0.3	0.3	0.8	-0.7	0.7	-0.3	0.4	-0.3	-0.9	-0.3	-0.6
Systolic blood pressure, automated reading	0.3	1.0	3.1	-0.6	-1.8	-1.1	0.3	-1.6	0.0	1.0	-0.1
Taking other prescription medications	0.3	0.4	1.6	-0.6	-0.2	-0.5	-1.3	-0.5	-0.6	0.1	-0.5
High blood pressure	0.3	0.9	2.0	0.9	-1.3	-0.4	1.4	1.3	0.8	-0.4	0.8
Sitting height	0.3	1.9	5.7	-0.3	1.7	-1.1	1.4	2.4	-0.9	-1.1	-0.8
Nervous feelings	0.3	0.6	2.3	0.1	-1.5	1.1	0.4	0.7	-0.4	-0.3	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.1	2.1	0.6	1.1	1.5	1.1	1.3	0.1	-1.3	0.1
Medication: Paracetamol	0.3	0.5	2.1	-0.0	-0.3	-0.5	0.9	1.5	-0.4	-0.4	-0.5
Age at first live birth	0.3	0.6	3.0	-0.5	0.6	-1.7	-0.2	-0.1	-0.6	0.5	-0.7
Pulse wave peak to peak time	0.3	0.4	1.4	-0.4	1.2	-0.7	0.2	0.5	-0.5	0.5	-0.5
Heart disease (mother)	0.3	0.4	0.9	-0.4	-0.4	0.3	-1.0	-0.4	-0.6	0.9	-0.5
Hypertension (Self-reported)	0.3	0.7	2.1	0.8	-0.9	-0.0	1.4	1.1	0.7	-0.5	0.6
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	1.1	0.5	-0.1	1.0	0.9	0.2	0.4	-0.6	0.5
Qualifications: nursing, teaching	0.3	0.5	1.5	0.5	1.2	0.5	-0.9	0.2	0.7	-0.5	0.6
Medication: Gliclazide	0.3	0.3	1.1	0.5	-0.4	0.1	0.6	0.7	-0.1	-1.0	0.2
Mother’s age at death	0.3	0.4	1.0	-0.3	0.7	0.1	1.0	0.4	-0.9	-0.5	-0.6
Illnesses of father: High blood pressure	0.3	0.4	2.4	-0.5	-1.5	-0.3	0.1	0.2	-0.5	0.0	-0.5
Unable to work because of sickness or disability	0.3	0.4	2.0	-0.6	0.2	1.4	-0.4	-0.3	-0.8	0.1	-0.5
Vascular/heart problems diagnosed by doctor	0.3	0.7	1.3	-1.0	1.0	0.1	-0.9	-0.7	-1.1	0.2	-1.0
Worry (Nagel 2018)	0.2	0.5	1.6	0.2	-0.7	0.1	1.1	1.3	-0.5	-0.7	-0.2
Body Mass Index (BMI) (2010)	0.2	0.3	0.9	-0.4	0.1	0.0	-0.9	-0.7	-0.3	0.5	-0.3
Type 2 Diabetes (T2D) (2012)	0.2	0.3	0.6	0.3	-0.7	0.8	0.5	0.6	-0.0	-0.5	0.1
Cardiovascular Disease	0.2	0.7	1.8	-0.6	-1.3	-0.8	-0.3	-0.8	-0.4	1.2	-0.7
Hypothyroidism (self reported)	0.2	0.6	1.7	0.6	0.4	-1.3	-0.7	-0.6	0.9	0.0	0.7
Respiratory disease	0.2	0.4	2.3	-0.3	0.2	-0.4	-1.5	-0.1	-0.2	0.3	-0.3
Lung FVC	0.2	1.0	3.7	0.6	1.1	1.9	0.9	-0.0	0.5	-1.3	0.5
Supplements: Zinc	0.2	0.2	0.5	-0.6	0.6	-0.1	-0.2	-0.1	-0.6	0.7	-0.2
Forced vital capacity (FVC)	0.2	0.8	2.1	0.6	0.7	1.0	1.4	0.8	0.3	-1.4	0.2
Heart attack	0.2	0.3	1.2	-0.3	-0.4	0.6	-1.1	0.1	-0.3	0.2	-0.4
Allergy	0.2	0.6	3.4	0.1	1.8	0.2	-0.0	-0.8	0.2	0.4	0.5
Pain all over the body in last month	0.2	0.2	0.5	0.6	0.1	-0.7	-0.1	-0.2	0.6	-0.4	0.7
Weight	0.2	1.0	2.6	-0.1	1.3	-1.0	1.4	1.6	-0.6	-0.8	0.0
Impedance of arm (right)	0.2	1.1	4.3	-0.8	-1.2	-0.6	-1.1	-2.1	-0.3	0.2	-0.7
Arm fat percentage (right)	0.2	0.7	2.9	-0.6	0.3	-0.9	-1.0	-1.7	-0.1	0.8	0.2
Forced expiratory volume in 1-second (FEV1)	0.2	0.8	1.6	-0.1	1.1	0.5	1.3	1.2	-0.5	-1.1	-0.6
Pulse rate	0.2	0.3	1.8	-0.3	-1.4	-0.6	-0.1	0.2	-0.3	-0.1	-0.5
Pulse wave Arterial Stiffness index	0.2	0.3	1.2	0.3	-1.1	0.5	0.1	-0.1	0.3	-0.7	0.4
Impedance of arm (left)	0.2	1.1	4.7	-0.5	-1.3	-0.7	-1.1	-2.2	0.1	0.2	-0.4
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	1.2	-0.3	0.1	-0.4	-0.9	-1.1	-0.0	0.2	-0.2
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	1.2	-0.4	-0.2	-0.8	1.1	-0.5	-0.3	-0.1	-0.1
Blood clot in the leg (DVT)	0.2	0.3	0.9	0.4	1.0	0.7	0.5	0.7	0.2	-0.4	-0.1
Glaucoma (self-reported)	0.2	0.3	0.9	-0.1	-0.4	-1.0	-0.4	0.2	-0.3	0.9	-0.2
Medication: Ventolin 100micrograms inhaler	0.2	0.2	0.5	0.6	-0.3	-0.0	-0.3	0.5	0.7	-0.4	0.7
Forced vital capacity (FVC), Best measure	0.2	0.8	2.4	0.6	1.0	1.5	1.1	0.7	0.2	-1.1	0.2
Migraine (self-reported)	0.2	0.3	1.3	0.2	-0.3	-0.4	-1.1	-0.4	0.0	-0.6	-0.1
Suffer from ‘nerves’	0.2	0.4	0.9	0.4	-0.4	0.9	0.6	0.7	-0.1	-0.9	0.0
Smoking status: Previous	0.2	0.3	0.9	0.2	0.6	0.7	-0.6	-1.0	0.6	0.2	0.4
Arm fat percentage (left)	0.2	0.8	3.1	-0.7	0.4	-1.1	-1.0	-1.8	-0.2	0.8	0.1
Loneliness, isolation	0.2	0.3	1.5	-0.3	-1.2	0.1	-0.7	-0.1	-0.6	-0.1	-0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.5	2.4	0.0	0.9	1.5	0.4	-0.0	-0.1	-0.7	-0.1
Number of self-reported non-cancer illnesses	0.2	0.4	0.9	0.8	-0.7	0.0	-0.6	-0.1	0.8	-0.4	0.9
Wears glasses or contact lenses	0.2	0.2	1.1	-0.3	0.1	-0.4	0.7	0.2	0.3	1.0	0.1
Medication: Blood pressure	0.2	0.5	1.3	-0.3	-0.7	0.2	-1.0	-0.5	-0.3	1.2	-0.7
Heart attack/myocardial infarction (self-reported)	0.2	0.2	1.0	-0.1	-0.1	0.7	-1.0	0.2	-0.1	0.0	-0.2
Heart disease (siblings)	0.2	0.2	0.4	0.4	0.5	0.3	-0.6	-0.6	-0.0	-0.7	0.3
Alcohol drinker status: Previous	0.2	0.2	0.7	-0.3	-0.6	0.1	0.3	0.8	-0.3	0.2	-0.5
BMI	0.1	0.8	2.3	1.1	0.2	-0.4	-0.3	-0.8	1.5	-0.6	1.5
Tanning	0.1	1.3	2.6	-1.3	0.4	0.0	-1.6	-0.6	-1.1	1.6	-1.4
Severe depression (siblings)	0.1	0.1	0.3	0.2	-0.3	0.4	0.6	0.2	-0.0	-0.5	0.2
Body mass index (BMI)	0.1	0.3	0.9	-0.4	1.0	-1.0	-0.4	-0.4	-0.2	0.5	0.1
Trunk fat mass	0.1	0.5	1.1	-0.8	0.5	-0.9	-0.6	-1.0	-0.6	0.5	-0.2
Diabetes (self-reported)	0.1	0.2	1.1	0.1	-0.2	1.0	0.0	-0.1	-0.0	-0.4	0.1
Hip circumference	0.1	0.6	2.3	0.2	1.5	-0.4	1.0	1.0	0.1	-0.6	0.4
Number of live births	0.1	0.2	0.8	0.2	0.9	0.4	0.1	0.0	0.4	-0.2	-0.0
Asthma	0.1	0.2	0.7	-0.1	0.5	0.1	-0.9	0.2	-0.2	-0.2	-0.4
Arm fat mass (right)	0.1	0.2	0.7	-0.3	0.8	-0.8	-0.1	-0.4	-0.1	0.1	0.3
Tense / ‘highly strung’	0.1	0.2	1.2	-0.0	-0.0	0.3	1.1	0.4	-0.2	-0.1	-0.1
Exposure to tobacco smoke outside home	0.1	0.2	0.6	0.2	0.6	0.0	-0.7	-0.1	0.5	0.4	0.3
Whole body fat mass	0.1	0.4	1.0	-0.8	0.6	-0.7	-0.6	-1.0	-0.6	0.5	-0.2
Leg fat mass (right)	0.1	0.5	1.6	-0.5	0.7	-0.1	-1.1	-1.3	-0.2	0.5	0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.5	0.0	0.2	-0.0	-0.7	-0.4	-0.1	-0.4	-0.4
Back pain experienced in last month	0.1	0.2	0.5	0.5	0.0	0.4	-0.7	-0.2	0.4	-0.5	0.3
Asthma (self-reported)	0.1	0.3	1.4	-0.3	0.4	0.1	-1.2	0.2	-0.4	0.2	-0.6
Osteoarthritis (self-reported)	0.1	0.2	0.9	-0.2	-0.1	0.3	-0.9	-0.3	-0.6	-0.0	-0.2
Arm fat mass (left)	0.1	0.2	0.6	-0.4	0.8	-0.8	-0.1	-0.4	-0.3	0.2	0.1
High cholesterol (Self-reported)	0.1	0.2	0.7	-0.3	0.1	-0.5	0.3	0.1	-0.3	0.8	-0.1
Number of operations (self-reported)	0.1	0.2	0.3	0.4	-0.3	0.5	-0.0	-0.3	0.5	-0.6	0.4
Leg fat mass (left)	0.1	0.4	1.2	-0.4	0.9	0.1	-0.7	-1.1	-0.2	0.4	0.2
Hair Pigment	0.0	0.7	3.9	-0.3	2.0	0.3	-1.0	-0.7	-0.3	0.4	-0.3
Waist circumference	0.0	0.2	0.8	-0.3	0.3	-0.9	-0.1	-0.1	-0.4	0.0	0.1

Hub : Genes

KLB

Models

Trait associations