Hub : Genes

LIAS

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1480 0.0620 4.1e-03 0.040 0.020 0.060 0.102 0.028 1.0e-05 1.4e-03 7.8e-08 2.0e-12 2.0e-04
2 GTEx Breast Mammary Tissue 0.2290 0.0720 1.4e-03 0.048 NA 0.104 NA 0.067 1.8e-03 NA 5.1e-06 NA 2.6e-04
3 GTEx Breast Mammary Tissue (Female) 0.2734 0.0987 1.1e-02 0.083 NA 0.151 NA 0.054 1.8e-03 NA 2.9e-05 NA 1.0e-02
4 METSIM Adipose 0.0882 0.0290 3.3e-06 0.003 0.031 0.025 0.030 0.023 1.1e-01 1.6e-05 1.1e-04 2.5e-05 1.6e-04
5 YFS Blood 0.4136 0.0420 0.0e+00 0.290 0.333 0.347 0.351 0.338 5.2e-96 3.9e-113 5.7e-119 1.0e-120 2.4e-115
6 TCGA Head and Neck Squamous Cell Carcinoma 0.0650 0.0259 1.1e-05 0.053 0.051 0.034 NA 0.035 1.3e-06 2.1e-06 8.5e-05 NA 7.8e-05
7 TCGA Pancreatic Adenocarcinoma 0.1810 0.0730 1.5e-03 -0.003 0.088 0.060 NA 0.019 4.3e-01 1.6e-04 1.6e-03 NA 5.0e-02
8 TCGA Thyroid Carcinoma 0.1010 0.0470 9.2e-06 0.035 0.052 0.027 NA 0.034 2.4e-04 8.1e-06 1.2e-03 NA 2.8e-04

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 1.5 2.4 8.7 -1.2 -0.9 -0.6 0.3 -1.3 -1.9 -1.5 -2.9
Bipolar Disorder or Schizophrenia 0.8 2.1 10.3 0.0 -0.8 -0.9 0.2 -0.9 -1.4 -1.4 -3.2
Depressed Affect (Nagel 2018) 1.3 2.7 8.5 -1.5 -0.9 -1.7 2.2 -2.9 0.1 -0.9 -1.0
Depression (Nagel 2018) 0.6 0.8 3.1 -1.2 -0.3 -0.9 0.5 -1.8 0.5 -0.4 -0.8
Intelligence (Savage-Jansen 2018) 1.0 3.1 14.6 -1.7 -1.5 -1.2 -1.3 -3.8 -0.4 -0.8 -1.2
Neuroticism (Nagel 2018) 1.0 2.3 9.2 -1.5 -0.1 -0.6 2.1 -3.0 0.6 -0.0 -1.4
Schizophrenia (2018) 0.3 0.6 3.0 1.0 -0.3 -0.7 -0.1 -0.1 -0.2 -0.6 -1.7
Schizophrenia vs Biploar Disorder 0.8 1.0 3.7 1.9 -0.7 -0.4 -0.5 0.6 1.1 -1.2 0.8
Worry (Nagel 2018) 0.5 1.0 2.5 1.0 -0.6 -0.9 0.5 -1.6 -0.6 -0.6 -1.6
Alzheimer’s Disease (in mother) 0.9 1.1 3.3 0.7 1.3 1.0 0.3 1.2 0.7 0.6 1.8
Alzheimer’s Disease (in father) 1.1 1.2 3.1 -0.5 1.8 1.5 0.5 0.8 0.4 1.5 0.5
Alzheimer’s Disease (including proxy) 1.4 2.0 5.2 0.7 1.6 1.6 -0.2 2.0 0.5 0.9 2.3
Crohns Disease (2017) 2.1 4.6 11.6 -1.0 2.4 2.6 0.4 -0.6 3.4 0.7 3.2
Irritable Bowel Disease (IBD) 1.8 4.2 12.7 -0.5 2.0 2.3 0.2 -0.0 3.6 0.4 3.4
Ulcerative Colitis (UC) 0.7 1.3 4.6 0.8 0.4 1.0 -0.2 0.5 1.9 -0.6 2.1
Major Depression (MDD) 0.9 1.1 4.2 -2.1 -0.3 -0.9 0.7 -0.5 -1.3 -0.8 -0.9
Reaction Time 0.7 1.4 4.7 2.2 -1.5 -1.0 -0.2 0.9 -1.4 -0.7 0.2
Verbal and Numeric Reasoning (VNR) 1.2 2.8 13.5 0.4 -1.3 -0.6 -1.6 -3.7 -0.3 -1.7 -0.9
Breast Cancer 0.5 1.1 3.4 0.4 -0.2 -1.3 -1.1 1.8 -1.2 0.8 -0.6
Ovarian Cancer 1.2 1.6 3.7 -1.3 1.1 1.5 0.4 -0.1 0.6 1.9 1.7
Prostate Cancer 1.0 1.4 6.3 -2.5 -0.2 0.5 1.2 -0.8 0.4 1.3 -0.6
Age at First Birth 0.6 0.9 3.1 -1.1 -0.9 -0.7 -1.8 -0.3 0.1 -1.2 -0.5
Bipolar Disorder (2011) 0.5 0.5 3.4 -0.8 -0.2 -0.1 -0.1 -1.8 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 0.2 0.3 1.3 1.1 0.0 0.1 -0.2 -0.3 0.7 0.1 0.6
Coronary Artery Disease (CAD) 1.9 2.3 4.9 -2.2 1.3 1.2 1.7 -0.2 1.9 0.6 1.7
Crohns Disease (2012) 2.0 3.2 9.5 -1.1 1.4 1.5 1.0 -1.1 3.1 -0.3 2.8
Mean Putamen Volume 0.7 0.8 2.6 0.1 -1.2 -1.6 0.5 -0.8 -0.7 -0.8 -0.8
Fasting Glucose 0.6 0.7 1.9 0.9 1.0 1.4 0.3 -0.5 0.5 -1.2 0.3
HbA1C 0.3 0.3 0.6 -0.8 -0.3 -0.1 0.7 -0.3 0.7 0.6 -0.2
HDL Cholesterol 1.3 2.1 7.1 0.2 1.4 1.3 0.6 2.0 -0.9 2.7 -1.1
LDL Cholesterol 1.2 1.9 3.5 -0.8 1.9 1.9 -1.0 1.3 1.1 -1.3 1.3
Lupus 0.6 0.9 2.8 1.4 0.5 -0.1 -1.7 -0.9 1.1 -0.4 0.1
Neuroticism (2016) 0.7 1.0 6.3 -0.1 0.8 0.3 2.5 -0.8 0.8 -0.2 -0.2
Primary Biliary Cirrhosis 0.3 0.4 1.2 -0.7 0.2 0.5 0.8 -0.7 1.1 0.6 0.0
Rheumatoid Arthritis 0.7 1.0 4.1 -1.5 -0.0 0.3 -2.0 -0.6 -0.3 0.2 0.8
Schizophrenia (2014) 0.3 0.7 2.6 1.2 -0.3 -0.6 -0.2 -0.1 -0.3 -1.0 -1.6
Triglycerides 1.0 1.6 5.5 1.3 -1.4 -1.1 -0.4 -0.4 -1.5 -2.4 0.2
Type 2 Diabetes (T2D) (2012) 0.5 0.5 2.2 1.5 -0.7 -0.0 0.6 -0.5 -0.5 -0.6 0.7
Ulcerative Colitis 0.7 1.1 4.2 0.8 0.3 -0.0 0.4 0.1 1.1 -2.0 1.4
Blood Eosinophil Count 0.5 4.2 10.0 0.8 -2.5 -1.4 -2.6 -1.1 -2.5 0.1 -3.2
Blood Platelet Count 0.6 6.7 10.2 -2.6 2.6 2.9 3.2 -0.3 2.9 1.9 3.1
Blood Red Count 0.5 4.9 10.6 -2.0 -2.6 -1.5 -0.9 -3.3 -1.7 -1.4 -3.1
Blood White Count 0.3 1.9 4.7 1.1 -1.0 -0.5 0.5 2.2 -1.8 0.3 2.0
Heel T-Score 1.0 8.3 26.1 1.4 -2.5 -1.6 -5.1 -2.9 -0.3 -4.5 -1.0
BMI 0.3 2.0 4.5 0.3 1.0 1.8 -1.2 2.1 -1.4 0.4 -1.8
Height 0.8 14.5 34.5 -4.9 -0.5 -0.8 5.9 -5.5 -0.3 2.1 -4.7
Waist Hip Ratio (WHR) 0.2 1.0 5.3 2.3 0.8 1.0 0.2 0.2 0.6 0.8 0.1
Systolic Blood Pressure 0.6 3.0 7.6 2.3 -0.1 1.3 -2.8 1.4 0.7 -1.5 2.2
Smoking Status 0.9 2.2 9.1 1.5 -1.2 -1.8 0.2 1.2 -3.0 0.1 -0.0
Allergy or Eczema 0.6 1.7 6.9 -2.6 -0.5 -0.9 0.0 -1.7 1.2 0.3 1.1
Cardiovascular Disease 0.3 0.8 3.1 0.7 0.4 1.0 0.0 0.9 0.9 -0.5 1.8
Hypothyroidism (self reported) 0.3 0.7 2.3 -0.5 1.0 0.6 -1.5 0.8 -0.3 0.1 -1.1
Respiratory disease 0.2 0.5 1.8 -0.1 0.6 -0.1 0.5 0.2 -0.1 1.3 1.2
Type 2 Diabetes (T2D) (2018) 0.3 0.6 1.8 0.9 0.0 0.1 0.4 0.6 -1.0 1.3 -0.8
Lung FEV1/FVC ratio 0.3 1.5 6.0 -0.8 -0.5 0.0 -1.1 -2.0 -0.5 -0.5 -2.4
Lung FVC 0.3 1.6 2.6 -1.1 -1.3 -1.1 1.1 1.0 -1.6 -1.6 0.9
Neuroticism 0.8 1.9 9.4 -0.7 -0.7 -0.9 1.4 -3.1 -0.4 -0.2 -1.4
Chronotype (morning person) 0.8 1.9 9.2 -3.0 1.3 1.7 0.1 -0.9 0.1 -0.3 -0.8
Hair Pigment 0.0 0.1 0.5 0.3 0.5 -0.1 0.3 0.1 0.3 -0.7 -0.0
Tanning 0.1 1.3 6.6 -0.3 0.3 -0.2 1.0 -0.8 1.4 0.4 2.6
Hand grip strength (left) 1.6 4.1 11.9 -1.0 -3.5 -3.1 -0.4 -1.2 -2.1 -1.9 -0.4
Number of treatments/medications taken 0.1 0.3 1.0 -0.1 -0.7 -0.2 -1.0 -0.7 -0.3 -0.1 -0.2
Average weekly spirits intake 0.7 0.9 3.9 -0.9 1.0 0.9 -0.5 0.7 -0.0 2.0 0.4
Sensitivity / hurt feelings 0.7 1.2 4.2 -1.2 0.6 0.2 0.2 -2.1 1.8 -0.0 -0.2
Frequency of depressed mood in last 2 weeks 0.3 0.5 1.2 -0.7 -0.4 -0.5 -0.2 -1.1 -0.1 -1.0 -0.8
Hearing difficulty/problems: Yes 0.4 0.6 2.7 0.2 -0.2 -0.0 0.2 -0.1 -1.3 -0.2 -1.6
Relative age of first facial hair 0.5 1.1 3.8 -0.3 2.0 1.6 0.6 1.3 0.4 0.1 0.2
Other serious medical condition/disability diagnosed by doctor 0.6 0.8 3.7 -0.2 -0.8 -0.6 -0.9 0.3 -0.6 -0.7 -1.9
Ever used hormone-replacement therapy (HRT) 0.4 0.5 1.2 -0.2 -0.1 0.7 1.1 0.1 0.9 0.6 1.0
Ever had hysterectomy (womb removed) 1.2 1.4 3.2 0.2 1.1 0.9 1.7 -0.9 1.8 1.4 0.3
Systolic blood pressure, automated reading 0.5 1.5 8.4 0.3 -0.0 0.8 -2.9 0.5 0.9 -1.2 0.2
Eye problems/disorders: Diabetes related eye disease 1.0 1.1 3.6 0.4 1.2 1.1 1.9 -0.0 1.4 0.4 0.6
Angina 2.0 2.6 7.2 -1.4 1.2 0.3 2.1 2.0 -0.2 1.1 2.7
Medication for hormone replacement therapy 1.2 1.3 7.0 0.7 -0.5 -0.7 -2.6 0.7 0.1 -1.3 -0.3
Vitamin and mineral supplements 0.4 0.5 1.1 0.5 0.6 0.1 0.9 1.1 -1.1 -0.4 0.1
Supplements: Zinc 0.7 0.8 2.3 -1.1 0.9 0.5 0.9 0.2 0.5 1.5 -0.7
Medication: Co-codamol 0.4 0.4 1.0 -0.9 -0.6 -0.9 0.3 -0.4 -0.4 -1.0 -0.4
Medication: Metformin 0.6 0.8 4.1 0.1 -1.0 -0.5 0.1 0.7 -2.0 0.2 -0.8
Diabetes (father) 0.6 0.7 2.1 1.4 -0.4 -1.1 -0.4 -0.7 0.6 0.8 0.8
Diabetes (mother) 0.8 1.1 4.0 0.2 -0.8 -0.2 -0.6 -0.0 -2.0 -1.0 -1.6
Severe depression (siblings) 0.8 0.9 2.4 1.5 -0.6 -0.3 0.3 -0.2 -1.0 -1.5 -0.9
Pack years adult smoking proportion 1.3 2.0 4.0 2.0 -1.4 -1.4 -0.7 -0.8 -1.7 -1.2 -1.5
Impedance of leg (right) 1.1 5.4 19.1 -0.9 2.3 1.7 1.9 0.9 2.4 2.3 4.4
Leg fat-free mass (left) 0.8 4.1 22.8 -0.9 -1.2 -1.0 -0.2 -1.7 -1.9 -0.4 -4.8
Trunk fat percentage 1.0 4.1 12.2 -1.1 3.1 3.5 -0.3 2.0 0.3 1.9 -1.5
Hand grip strength (right) 2.2 5.9 13.8 -0.9 -3.7 -3.7 -0.9 -2.2 -2.5 -2.3 -1.1
Townsend deprivation index at recruitment 0.2 0.2 0.7 0.8 0.2 -0.3 0.2 0.4 -0.4 -0.1 -0.7
Current tobacco smoking 1.0 1.7 5.1 0.6 -1.0 -2.2 -0.9 -0.0 -2.3 -0.7 -1.0
Average weekly fortified wine intake 1.0 1.1 4.3 1.4 -0.8 -0.4 -0.0 -2.1 0.5 -0.9 -1.0
Maternal smoking around birth 1.8 2.6 5.7 2.3 1.7 1.0 1.8 0.8 0.0 1.5 2.4
Fed-up feelings 0.7 1.3 3.2 -0.6 -0.8 -1.7 0.7 -1.8 -1.0 -0.7 -1.3
Frequency of unenthusiasm / disinterest in last 2 weeks 0.6 0.8 1.6 -0.6 -0.0 -1.1 -0.2 -1.2 -0.7 -1.2 -1.0
Relative age voice broke 1.1 1.7 5.0 -0.4 2.2 2.0 0.7 1.4 1.2 0.5 0.2
Taking other prescription medications 0.3 0.5 1.2 -1.1 0.6 0.2 0.4 -0.1 -0.9 0.9 -0.8
Age when periods started (menarche) 0.2 0.6 1.9 1.4 -0.4 -0.6 -0.1 -0.5 -0.6 -0.2 -1.3
Bilateral oophorectomy (both ovaries removed) 0.5 0.6 2.0 0.5 -0.4 -0.5 1.0 -0.7 0.7 -1.4 0.2
Heel bone mineral density (BMD) T-score, automated (left) 0.5 1.2 3.6 0.4 -0.6 0.7 -0.3 -1.9 1.1 -1.7 0.6
Tinnitus: Yes, but not now, but have in the past 1.0 1.0 2.9 1.1 0.9 0.8 -0.1 1.7 -1.4 0.8 0.3
Qualifications: CSEs or equivalent 0.9 1.2 6.2 -0.1 0.2 0.3 0.2 -2.5 1.5 -0.4 0.8
Serious illness, injury or assault to yourself 0.7 0.9 2.0 0.8 0.3 1.4 -0.8 1.4 -0.9 0.8 0.3
High blood pressure 0.3 0.9 3.7 0.4 -1.0 -0.5 -0.7 -0.1 -1.0 -1.9 -0.9
Hayfever, allergic rhinitis or eczema 0.7 1.5 6.2 -2.5 -0.8 -1.2 -0.4 -1.7 -0.0 0.3 0.8
Multivitamins +/- minerals 0.4 0.5 2.7 -0.2 -0.4 -0.1 -0.3 -0.7 1.6 0.3 -0.0
Stomach or abdominal pain in last month 0.3 0.3 0.8 0.3 -0.7 -0.9 0.8 -0.6 0.2 0.2 0.3
Supplements: Glucosamine 0.7 1.0 4.1 -0.6 0.1 -0.0 -2.0 -0.7 -0.8 -1.1 -0.9
Diverticular disease/diverticulitis (self-reported) 1.4 1.7 4.4 1.6 -1.6 -0.9 0.3 -1.3 1.0 -0.7 2.1
Medication: Atenolol 0.8 1.0 2.8 0.6 0.9 1.2 0.6 1.4 -0.2 -0.2 1.7
Medication: Levothyroxine sodium 0.4 0.7 2.7 -1.1 0.7 0.7 -1.7 0.3 0.2 0.0 -0.8
Sitting height 0.3 2.3 7.6 -1.6 0.1 -0.0 2.8 -1.7 -0.3 1.9 -1.4
Chronic bronchitis/emphysema (father) 1.7 2.0 4.4 1.2 -2.1 -1.8 -1.9 0.2 -1.4 -1.1 0.3
High blood pressure (mother) 0.7 0.9 5.6 2.4 -0.1 -0.0 -0.3 -0.7 -0.6 0.9 0.4
Body mass index (BMI) 0.4 1.6 6.0 -0.3 1.3 1.9 -0.6 0.8 -0.5 0.1 -2.5
Impedance of leg (left) 1.0 5.0 17.8 -1.2 2.0 1.7 2.0 0.8 2.5 1.8 4.2
Leg predicted mass (left) 0.8 4.2 23.5 -1.0 -1.2 -1.0 -0.2 -1.7 -1.9 -0.5 -4.8
Trunk fat mass 0.7 3.0 7.4 -1.3 2.3 2.7 -0.0 1.2 -0.2 1.4 -2.4
Waist circumference 0.6 2.0 9.6 0.1 1.3 1.9 -0.1 0.1 -0.8 0.5 -3.1
Number of incorrect matches in round 1.3 2.1 7.3 -0.7 2.0 0.8 0.9 2.7 -1.4 1.2 -0.6
Past tobacco smoking 0.3 0.6 2.1 0.1 0.2 0.9 0.0 -1.4 1.2 0.3 0.1
Alcohol usually taken with meals 0.8 1.3 3.8 -2.0 -1.4 -0.8 -1.1 -0.7 0.2 -1.0 0.9
Nervous feelings 0.3 0.5 1.2 0.8 -0.5 -0.7 0.9 -1.1 0.1 -0.1 -0.5
Frequency of tenseness / restlessness in last 2 weeks 1.0 1.6 3.5 0.4 -1.3 -1.9 -0.5 -0.9 -1.6 -1.7 -0.9
Hearing difficulty/problems with background noise 0.7 1.1 3.8 0.6 0.3 0.8 0.4 0.6 -2.0 0.8 -1.7
Hair/balding pattern: Pattern 2 1.0 1.3 3.0 -1.7 -0.1 0.7 1.3 -1.0 1.3 -0.3 1.5
Had menopause 0.5 0.6 2.7 -0.5 0.0 1.0 0.7 -0.4 1.7 0.4 0.4
Had other major operations 0.7 0.8 2.9 0.0 1.2 0.7 -0.7 -0.1 1.7 1.1 -0.3
Forced vital capacity (FVC) 0.2 0.9 2.1 -0.4 -1.5 -1.1 1.2 -0.3 -1.1 -0.7 0.3
Heel bone mineral density (BMD) T-score, automated (right) 0.7 1.6 4.4 0.0 -0.2 0.9 -0.4 -2.1 2.0 -1.9 -0.0
Ever unenthusiastic/disinterested for a whole week 1.6 2.0 5.1 -1.6 -2.3 -1.5 0.2 -1.1 -1.2 -1.4 -1.1
Qualifications: None of the above 0.5 1.1 3.0 -0.3 1.6 0.5 1.7 0.8 -0.2 1.3 -0.6
Financial difficulties in last 2 years 0.7 0.9 3.1 0.3 -0.2 -0.9 -0.5 1.4 -0.8 -0.8 -1.8
Mouth/teeth dental problems 0.4 0.6 1.1 0.8 -0.6 -1.0 1.0 1.0 0.2 1.0 0.4
Heart attack 0.1 0.2 0.5 -0.0 0.2 -0.0 0.7 0.3 0.3 0.5 0.5
Allergy 0.6 1.3 7.1 2.7 0.7 0.9 0.3 0.9 0.8 -0.4 -0.5
Pain all over the body in last month 0.3 0.3 1.4 0.4 -0.0 -0.4 0.4 -0.1 -0.6 0.3 -1.2
Diabetes (self-reported) 0.3 0.4 1.2 -0.0 0.8 1.0 0.3 0.5 0.1 1.1 -0.2
Hayfever/allergic rhinitis (self-reported) 0.9 1.1 3.7 -0.9 0.7 -0.3 0.4 -0.9 1.4 1.9 1.1
Medication: Ramipril 0.8 1.1 3.1 1.7 0.1 0.9 -0.8 1.0 -0.8 -1.2 -0.9
Medication: Simvastatin 0.5 0.7 1.9 0.4 1.1 1.2 0.3 -0.0 1.4 -0.8 0.4
Fluid intelligence score 0.3 0.7 3.1 0.2 -0.4 0.4 -0.7 -1.8 -0.0 -1.1 -0.8
Illnesses of siblings 0.5 0.7 3.5 -1.9 1.1 -0.0 -0.1 -0.7 0.6 -0.1 -0.6
Neuroticism score 0.9 1.8 5.4 0.1 -1.3 -1.8 0.4 -2.3 -1.0 -1.0 -1.4
Weight 0.6 2.9 16.6 -1.8 0.3 0.8 0.5 -1.0 -1.2 0.4 -4.1
Impedance of arm (right) 0.3 1.2 3.6 -0.5 0.7 0.2 -1.2 0.7 1.0 1.6 1.9
Arm fat percentage (right) 0.7 2.8 7.1 -0.3 2.2 2.7 -1.4 1.9 -0.4 0.9 -2.0
Trunk fat-free mass 1.0 5.9 21.2 -2.0 -1.9 -1.9 1.3 -3.1 -1.8 -0.8 -4.6
Hip circumference 0.4 1.6 9.4 -0.7 0.7 1.1 0.0 0.2 -1.1 0.5 -3.1
Time employed in main current job 0.8 0.9 1.7 -1.1 -0.8 -1.3 -1.0 -0.2 -1.3 -0.2 -0.9
Alcohol intake versus 10 years previously 1.1 1.6 5.7 -0.2 -0.3 -0.5 1.0 -0.8 -2.0 1.1 -2.4
Father’s age at death 0.6 0.8 2.6 0.5 0.8 0.4 0.8 -1.6 0.6 1.1 -0.5
Worrier / anxious feelings 0.3 0.6 2.5 -0.9 0.1 0.1 -0.0 -1.6 0.4 -0.9 -0.5
Frequency of tiredness / lethargy in last 2 weeks 1.2 2.0 7.2 -0.3 0.2 -1.0 -0.1 -2.6 0.8 -0.7 -2.7
Falls in the last year 0.4 0.5 1.4 -1.1 0.1 0.0 -0.1 -0.8 -0.4 -1.2 -0.7
Hair/balding pattern: Pattern 3 0.5 0.8 3.1 0.1 -0.5 -0.8 -0.7 1.0 0.6 -0.5 1.8
Number of live births 0.5 0.7 2.1 1.1 -0.1 0.6 0.3 0.6 0.3 1.3 1.4
Forced expiratory volume in 1-second (FEV1) 0.2 0.8 1.5 -0.9 -1.1 -0.7 1.2 -1.1 -0.8 -0.3 -0.2
Pulse rate 0.1 0.1 0.4 -0.2 0.0 -0.1 -0.7 -0.5 -0.3 0.3 -0.1
Happiness 0.9 1.1 3.8 -1.0 -0.5 0.3 -1.5 -0.4 -1.0 -0.6 -1.9
Noisy workplace 1.4 1.7 3.4 1.9 -1.5 -0.8 -1.4 1.1 -1.5 -0.6 1.4
Qualifications: A levels/AS levels or equivalent 1.0 2.3 4.4 -0.8 -2.0 -1.2 -2.1 -1.3 -0.9 -1.7 -1.6
Serious illness, injury or assault of a close relative in last 2 years 0.1 0.1 0.5 -0.1 0.3 0.5 0.3 -0.3 0.7 -0.2 0.2
Mouth/teeth dental problems: Dentures 1.3 2.2 4.8 -0.7 2.2 2.2 0.9 -0.0 1.8 0.1 1.9
Asthma 0.1 0.2 0.5 -0.6 -0.0 0.0 0.7 -0.3 -0.4 0.7 0.3
Medication: Ibuprofen (e.g. Nurofen) 3.0 3.8 7.0 -1.9 -2.0 -2.1 -0.8 -1.0 -2.6 -1.8 -2.6
Medication: Cholesterol lowering 0.3 0.5 1.7 0.8 0.2 0.8 -0.0 -0.2 1.0 0.2 1.3
Depression (self-reported) 3.2 3.8 7.0 -1.6 -2.2 -2.4 -0.4 -1.9 -1.7 -2.6 -1.9
Medication: Lansoprazole 0.4 0.4 1.4 -0.7 0.2 -0.1 0.5 0.5 -0.9 1.2 0.4
Prospective memory result 0.9 1.2 3.8 -1.5 -0.5 -1.3 -0.4 0.9 -1.9 0.2 -0.6
Lung cancer (father) 0.4 0.5 1.9 -0.6 0.3 0.2 0.1 -0.4 0.1 1.2 -1.4
Illnesses of mother 0.8 1.0 2.7 -0.8 -1.0 -0.5 -0.1 -1.1 0.2 -1.4 -1.7
Forced expiratory volume in 1-second (FEV1), Best measure 0.3 0.8 2.6 0.5 -0.9 -0.9 1.6 -1.1 -0.7 -0.2 -0.7
Pulse wave Arterial Stiffness index 0.4 0.5 1.6 -0.6 -0.8 -0.2 -1.1 -0.0 -0.5 -1.2 0.1
Impedance of arm (left) 0.4 1.6 3.7 0.2 1.0 0.7 -1.4 1.2 1.0 1.8 1.9
Arm fat mass (right) 0.5 2.1 8.9 -0.8 1.3 1.8 -0.5 0.9 -0.9 0.5 -3.0
Trunk predicted mass 1.1 6.0 21.6 -1.9 -2.0 -1.9 1.3 -3.1 -1.8 -0.9 -4.7
Standing height 0.8 8.0 16.4 -3.5 -2.1 -2.6 2.4 -4.0 -1.6 0.5 -4.0
Length of working week for main job 0.5 0.5 2.5 -0.4 0.1 -0.3 1.6 0.3 0.4 0.7 0.8
Exposure to tobacco smoke at home 1.4 1.6 4.0 -1.7 1.4 0.9 1.5 -0.2 0.4 2.0 0.7
Breastfed as a baby 2.3 2.8 7.4 2.7 -1.3 -0.6 -2.6 -0.7 1.3 -2.0 -0.3
Tense / ‘highly strung’ 0.4 0.7 3.4 0.3 0.5 -0.4 -0.2 -0.3 -0.7 -0.9 -1.9
Seen doctor (GP) for nerves, anxiety, tension or depression 1.8 2.8 10.9 -3.3 -0.5 -0.7 0.2 -3.0 0.2 0.2 -1.5
Hair/balding pattern: Pattern 4 1.0 2.3 10.7 0.5 1.0 0.1 0.7 0.0 -1.2 2.2 -3.3
Birth weight of first child 0.7 1.3 3.0 -1.5 0.3 -0.3 1.7 -1.4 1.1 1.2 0.0
Peak expiratory flow (PEF) 0.4 0.9 3.8 0.6 -1.1 -1.1 -0.3 -0.2 -1.9 0.2 -0.4
Pulse wave reflection index 0.6 0.8 3.1 1.8 0.3 0.9 -0.9 1.1 -0.1 -0.2 -0.3
Ever highly irritable/argumentative for 2 days 1.8 2.2 7.1 1.5 -1.8 -1.7 1.0 0.8 -2.7 -0.5 -0.0
Loud music exposure frequency 0.9 1.0 3.1 -0.7 -1.3 -1.4 -0.0 -1.8 -0.7 0.4 -0.4
Qualifications: O levels/GCSEs or equivalent 0.8 1.2 2.6 1.1 -1.1 -1.1 -1.6 -0.9 0.7 -1.5 -0.1
Mouth/teeth dental problems: Bleeding gums 0.9 1.1 4.6 0.4 -0.7 0.0 -2.1 -0.7 -0.7 -1.4 -0.8
Blood clot in the leg (DVT) 0.4 0.5 2.4 0.9 -0.2 0.1 1.6 0.2 0.5 0.5 0.5
Medication: Paracetamol 0.8 1.4 5.6 -2.4 -0.4 -1.3 1.0 -0.8 -0.4 0.8 -1.1
Headache pain in last month 0.9 1.6 5.5 -1.1 -1.4 -2.4 1.0 -1.3 -0.5 -0.3 -1.0
Medication for cholesterol, blood pressure or diabetes 0.8 1.4 3.0 -1.0 1.6 0.6 1.5 -0.6 1.0 1.7 -0.7
Glaucoma (self-reported) 1.0 1.2 2.7 0.9 1.4 1.5 0.3 -0.5 0.3 1.6 -1.2
Gout (self-reported) 1.5 2.1 4.2 0.6 1.5 1.3 1.1 1.4 1.2 2.1 1.9
Hypothyroidism/myxoedema (self-reported) 0.6 1.2 3.4 -1.8 1.1 1.2 -1.3 0.6 -0.2 -0.2 -1.2
Medication: Amlodipine 0.5 0.6 2.0 -0.2 -0.8 -0.5 0.4 -0.1 -1.4 -1.4 -0.1
Medication: Ventolin 100micrograms inhaler 0.3 0.3 1.0 -0.2 -0.6 -1.0 -0.4 -0.1 -0.9 0.1 0.4
Birth weight 0.7 1.5 8.1 0.2 -0.2 -0.8 2.9 0.1 0.1 1.7 0.2
Chronic bronchitis/emphysema (mother) 1.4 1.6 5.4 -0.5 1.0 0.5 1.3 0.5 1.0 2.3 1.7
High blood pressure (siblings) 1.1 1.6 7.6 2.8 -1.4 -0.1 -0.9 0.2 -0.4 -1.1 0.8
Forced vital capacity (FVC), Best measure 0.2 0.9 4.0 0.6 -1.0 -1.0 2.0 -0.5 -0.6 -0.4 0.1
Body fat percentage 1.1 4.2 14.1 -0.7 3.2 3.8 -0.3 2.2 0.5 1.6 -1.1
Leg fat percentage (right) 1.0 3.5 12.4 -0.5 3.1 3.5 0.1 2.0 0.7 1.0 -0.6
Arm fat-free mass (right) 0.7 3.6 15.9 -1.5 -0.9 -0.5 1.6 -2.4 -1.1 -0.6 -4.0
Exposure to tobacco smoke outside home 0.3 0.4 1.4 1.2 0.4 -0.1 -1.1 -0.2 0.2 -0.2 0.1
Comparative body size at age 10 1.2 3.2 7.7 2.6 -1.6 -1.6 0.1 0.4 -2.8 -1.0 -2.2
Number of full brothers 0.3 0.4 1.8 1.3 0.5 0.1 0.3 0.9 0.1 0.6 -0.5
Worry too long after embarrassment 0.4 0.6 1.4 0.0 -0.2 -0.4 0.9 -0.9 -1.1 0.7 -1.2
Seen a psychiatrist for nerves, anxiety, tension or depression 1.3 1.7 5.7 -1.2 0.8 -0.2 2.4 -1.5 0.9 1.3 -1.0
Wheeze or whistling in the chest in last year 0.4 0.7 3.1 1.0 -0.8 -1.8 -0.4 -0.5 -0.7 -0.5 0.1
Number of children fathered 0.3 0.4 1.6 0.3 0.3 0.4 1.0 0.0 1.3 0.0 0.1
Reason for reducing amount of alcohol drunk: Health precaution 3.5 4.1 12.8 3.6 1.2 2.3 -0.3 1.8 1.2 0.1 2.9
Age at first live birth 0.2 0.4 1.7 0.2 0.2 0.1 -1.3 -0.6 1.0 0.6 0.3
Pulse wave peak to peak time 0.4 0.5 1.4 0.3 0.7 0.0 1.2 -0.4 0.4 1.1 -0.4
Health satisfaction 1.9 2.5 6.5 2.5 0.9 1.3 0.7 2.5 -1.3 1.0 1.1
Shortness of breath walking on level ground 1.0 1.2 3.5 -0.4 1.3 0.5 1.0 1.4 0.9 1.9 0.4
Qualifications: College or University degree 0.3 1.1 3.3 -0.2 -1.7 -0.6 -1.8 -1.3 0.3 0.0 0.5
Eye problems/disorders: None of the above 0.3 0.3 0.8 0.6 -0.8 -0.1 0.2 -0.2 0.2 -0.9 0.8
Mouth/teeth dental problems: Loose teeth 1.6 1.9 5.6 2.4 -0.2 0.2 -0.8 1.3 -1.9 -0.7 -1.7
Emphysema/chronic bronchitis 1.4 1.5 2.3 0.9 -1.5 -1.4 -0.8 -1.5 -1.4 -1.3 -0.9
Medication for pain relief, constipation, heartburn 1.2 2.0 6.1 1.6 0.5 1.1 -1.4 0.2 2.5 -0.9 1.7
Neck or shoulder pain in last month 0.4 0.6 2.4 0.6 0.2 -0.3 1.5 1.1 -0.6 0.5 0.2
Medication: Blood pressure 1.3 2.2 3.5 1.7 -1.4 -0.2 -1.5 1.7 -1.9 -1.9 0.9
Angina (self-reported) 2.1 2.7 7.3 -1.4 1.4 0.3 2.1 2.0 0.0 1.4 2.7
Migraine (self-reported) 0.3 0.4 1.7 0.2 0.2 -0.3 0.7 -0.0 -0.2 1.0 1.3
Medication: Ibuprofen 4.4 5.3 9.3 -0.5 -3.0 -2.7 -1.2 -1.8 -2.7 -3.0 -2.2
Medication: Allopurinol 1.8 2.4 4.4 0.1 1.7 1.5 1.1 1.5 1.4 2.1 2.0
Medication: Omeprazole 0.5 0.5 1.6 0.2 -0.7 -0.8 1.2 -0.6 -0.4 1.0 -0.1
Medication: Seretide 50 evohaler 0.9 1.0 4.3 0.9 -0.6 -0.5 0.7 0.5 -0.6 1.1 2.1
Mean time to correctly identify matches 1.1 2.0 4.9 2.2 -1.6 -0.8 -0.5 1.4 -2.0 -1.2 -0.6
Heart disease (mother) 0.2 0.2 0.7 -0.2 0.5 0.4 0.8 0.1 0.1 0.6 0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.8 2.1 8.5 2.9 -1.6 -0.6 -1.2 -0.6 -0.1 0.5 1.8
Whole body fat mass 0.6 2.5 6.4 -1.1 2.1 2.5 0.3 1.1 -0.2 1.3 -2.3
Leg fat mass (right) 0.5 1.9 5.1 -0.7 1.9 2.2 0.3 1.3 -0.4 0.8 -1.9
Arm predicted mass (right) 0.7 3.5 14.7 -1.4 -1.0 -0.6 1.7 -2.4 -1.3 -0.5 -3.8
Pulse rate, automated reading 0.7 2.4 6.2 -2.5 1.3 1.8 0.2 0.1 2.2 0.6 1.6
Alcohol intake frequency. 7.1 16.5 36.8 -5.3 -3.5 -4.9 -1.5 -3.8 -3.6 -0.7 -6.1
Comparative height size at age 10 1.0 5.7 15.2 -3.7 -1.6 -0.9 1.2 -2.1 -2.6 0.3 -3.9
Number of full sisters 1.9 2.3 4.8 1.3 1.6 2.2 2.1 0.7 1.0 1.4 1.2
Suffer from ‘nerves’ 0.4 0.6 1.7 1.0 -0.5 -0.8 1.3 -0.7 -0.5 -0.3 0.3
Overall health rating 0.6 1.3 4.3 2.1 1.0 0.1 1.5 1.2 -0.4 1.1 -0.4
Chest pain or discomfort 0.3 0.4 1.2 1.1 0.4 -0.7 0.3 0.7 -0.6 0.7 -0.5
Had major operations 2.4 2.8 8.6 -2.9 -1.3 -1.7 -0.9 -0.5 -2.1 -1.5 -1.1
Age at last live birth 0.8 1.1 3.6 0.3 -0.2 0.1 -0.0 -1.8 1.9 0.5 1.3
Family relationship satisfaction 1.1 1.3 6.4 1.3 0.0 0.1 -1.1 0.5 -0.4 -0.8 -2.5
Leg pain on walking 0.7 0.9 3.9 0.5 -0.8 -0.3 -0.3 -0.8 -2.0 -1.0 -0.7
Qualifications: NVQ or HND or HNC or equivalent 0.3 0.4 1.3 0.8 -0.2 -0.5 -0.1 0.4 -0.1 -1.1 0.8
Commuting to job workplace: Car/motor vehicle 0.4 0.4 1.1 -0.8 -0.9 -1.1 -0.4 -0.4 -0.7 0.5 0.0
Illness, injury, bereavement, stress in last 2 years 0.6 0.7 3.3 1.8 0.4 0.2 -0.3 0.4 0.1 1.1 0.8
Medication: Aspirin 1.7 2.3 6.1 -1.3 2.0 2.0 1.1 1.1 0.3 2.5 0.3
Supplements: Vitamin C 0.4 0.5 1.9 -0.0 -0.1 0.5 -0.2 -1.4 0.9 0.6 0.6
Knee pain experienced in last month 0.7 1.0 4.7 1.0 0.3 -0.8 -0.3 -0.0 -1.2 -0.7 -2.2
Hypertension (Self-reported) 0.3 0.8 3.7 0.6 -1.0 -0.3 -0.5 -0.2 -0.8 -1.9 -0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 2.0 2.3 5.4 -0.4 -2.1 -1.5 0.1 -0.9 -2.3 -1.2 -2.1
Illnesses of father: Heart disease 0.3 0.3 1.2 -0.5 0.2 0.8 1.1 -0.3 -0.4 0.3 0.5
Illnesses of siblings: Diabetes 0.8 1.0 2.8 -0.1 -0.7 -0.6 1.6 1.7 -1.0 0.6 -0.2
Smoking status: Previous 0.6 0.9 3.7 0.1 0.9 0.8 0.9 1.9 -0.3 0.9 0.7
Forced expiratory volume in 1-second (FEV1), predicted 0.2 0.5 2.1 0.4 -0.0 0.1 1.4 -1.2 0.6 0.0 -0.3
Whole body fat-free mass 0.9 5.2 23.3 -1.6 -1.6 -1.4 0.9 -2.6 -1.8 -0.7 -4.8
Leg fat-free mass (right) 1.0 5.1 25.8 -1.3 -1.6 -1.3 -0.3 -2.2 -1.9 -0.9 -5.1
Arm fat percentage (left) 0.8 3.0 8.9 0.1 2.3 3.0 -1.5 1.9 -0.2 1.0 -1.8
Average weekly red wine intake 0.6 0.9 3.6 0.6 -0.1 0.4 0.0 0.3 1.5 0.8 1.9
Handedness (chirality/laterality): Left-handed 0.4 0.5 1.7 1.3 0.4 0.9 0.3 -0.2 0.9 0.8 -0.0
Mood swings 1.1 2.0 8.3 -1.0 -1.1 -1.5 0.5 -2.9 0.2 -1.5 -1.0
Loneliness, isolation 0.3 0.3 1.2 0.3 0.2 -1.1 1.0 -0.2 -0.3 -0.2 0.6
Long-standing illness, disability or infirmity 1.0 1.5 4.4 0.3 -1.7 -1.5 -0.4 -0.5 -2.1 -1.1 -1.0
Ever had bowel cancer screening 0.3 0.4 2.3 0.1 -0.3 0.1 -0.1 -0.7 0.1 -0.3 -1.5
Diabetes diagnosed by doctor 0.4 0.7 2.1 0.4 0.5 0.4 -0.0 1.5 -1.0 1.3 -0.5
Ever had stillbirth, spontaneous miscarriage or termination 0.9 0.9 2.2 1.5 -1.4 -0.2 -0.7 -0.2 -0.7 -1.4 -0.2
Friendships satisfaction 1.5 1.9 3.7 1.6 -1.2 -0.8 -1.3 0.2 -1.1 -1.9 -1.9
Qualifications: nursing, teaching 0.1 0.1 0.4 0.6 -0.1 0.0 -0.1 -0.3 -0.2 0.6 0.1
Commuting to job workplace: Walk 0.2 0.2 0.7 -0.3 0.5 0.4 0.2 0.1 0.8 0.2 -0.6
Eye problems/disorders: Cataract 0.4 0.5 1.5 0.3 0.1 -1.0 -1.2 0.8 -0.2 0.7 -0.2
Mouth/teeth dental problems: Mouth ulcers 1.3 2.1 6.2 -2.5 -0.4 -0.6 -0.3 -2.4 -0.3 -0.5 -2.0
Medication for cholesterol 1.1 1.6 4.0 -2.0 -0.8 -1.4 1.6 -1.2 -1.0 1.1 -0.3
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.9 1.1 5.7 -0.4 -0.4 -0.7 2.4 0.5 0.2 1.1 0.9
Back pain experienced in last month 0.3 0.5 2.4 0.0 -0.1 0.1 1.5 0.4 -0.9 0.3 -0.5
Mineral and other dietary supplements 0.1 0.2 0.6 -0.2 -0.6 -0.3 0.1 -0.3 -0.8 0.0 0.4
Breast cancer (self-reported) 1.3 1.5 4.0 0.4 1.6 1.1 0.9 -0.1 1.6 2.0 0.8
Asthma (self-reported) 0.2 0.4 1.0 -0.8 0.2 0.1 0.8 -0.3 -0.1 1.0 0.6
Osteoporosis (self-reported) 1.0 1.2 2.5 -1.0 -1.5 -1.6 -1.0 -0.4 -0.6 -1.4 0.2
Osteoarthritis (self-reported) 0.3 0.4 1.0 0.8 0.1 0.1 0.8 -1.0 -0.4 0.3 -0.8
Medication: Aspirin 1.5 2.0 5.7 -1.5 1.6 1.9 0.7 1.0 0.3 2.4 0.2
Medication: Gliclazide 0.2 0.2 0.6 0.8 -0.3 -0.2 0.7 -0.3 -0.6 -0.3 -0.1
Illnesses of father: None of the above (group 1) 0.4 0.5 1.5 0.1 1.2 0.7 -0.1 0.8 1.0 -0.1 -0.5
Smoking status: Current 0.8 1.3 3.9 0.9 -0.9 -2.0 -0.4 0.0 -2.0 -0.6 -0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.3 0.7 3.2 -0.3 0.4 1.0 1.8 0.5 -0.0 0.4 0.7
Whole body water mass 0.9 5.2 23.0 -1.6 -1.6 -1.4 0.8 -2.6 -1.8 -0.7 -4.8
Leg predicted mass (right) 1.0 5.1 25.6 -1.3 -1.6 -1.3 -0.3 -2.1 -1.9 -0.9 -5.1
Arm fat mass (left) 0.5 2.1 8.2 -0.8 1.4 1.9 -0.4 0.8 -0.7 0.6 -2.9
Number of self-reported non-cancer illnesses 0.2 0.4 1.0 0.4 -0.4 -1.0 -1.0 0.4 -0.4 -0.4 -0.8
Average weekly champagne plus white wine intake 0.6 0.8 2.7 -0.3 1.1 1.1 -0.0 -0.3 1.7 0.4 1.1
Miserableness 1.3 2.2 4.2 -1.6 -1.3 -2.0 1.6 -2.0 -1.1 -0.7 -0.9
Guilty feelings 1.6 2.4 5.7 -2.4 -1.7 -1.9 1.8 -1.2 -1.0 -0.6 -1.0
Wears glasses or contact lenses 1.0 1.2 2.8 -0.0 1.6 1.5 -1.2 1.7 0.0 0.6 0.1
Ever taken oral contraceptive pill 1.6 1.8 6.0 -0.1 -1.8 -1.4 0.2 1.8 -2.4 -0.5 -0.4
Hearing aid user 0.3 0.3 0.7 -0.2 0.4 0.7 -0.5 -0.8 0.8 0.6 0.0
Mother’s age at death 0.3 0.4 1.2 -0.2 -0.1 -0.6 0.5 -0.9 -0.0 -0.9 -1.1
Financial situation satisfaction 0.6 0.8 3.5 1.9 -0.2 -0.2 -0.9 1.1 -0.2 -0.6 0.6
Tinnitus: Yes, now most or all of the time 1.2 1.4 4.5 1.5 -1.3 -0.7 2.1 1.1 -0.8 0.5 0.6
Commuting to job workplace: Public transport 0.6 0.7 2.4 -1.5 -0.4 -0.9 -0.1 -1.1 -0.3 -1.0 -0.1
Eye problems/disorders: Glaucoma 0.6 0.7 1.5 0.2 1.1 1.2 0.3 -0.5 0.6 1.1 -0.9
Medication: Blood pressure 0.2 0.4 1.3 1.1 0.2 0.6 0.5 0.1 0.6 -0.8 0.3
Pain type(s) experienced in last month: Hip pain 0.5 0.6 1.7 1.3 -0.2 -1.3 -0.7 -0.3 -0.7 -0.3 -0.8
Supplements: Fish oil (including cod liver oil) 0.3 0.4 1.1 1.0 0.2 0.3 0.9 -0.1 1.0 -0.1 0.2
High cholesterol (Self-reported) 0.4 0.8 3.1 -0.7 -0.4 -0.1 -1.2 -0.1 0.2 -1.8 -0.9
Medication: Bendroflumethiazide 0.2 0.3 1.2 -0.4 -0.2 -0.0 -0.8 0.2 -0.0 -1.1 0.1
Medication: Paracetamol 1.0 1.5 6.2 -2.5 0.1 -1.1 0.7 -1.4 0.7 1.2 -0.6
Medication: Lisinopril 0.3 0.3 1.0 0.7 -0.4 0.2 0.3 0.4 -0.1 -1.0 0.7
Medication: Atorvastatin 0.4 0.5 1.0 -1.0 -0.4 -0.5 -0.8 0.9 -0.6 0.6 0.7
Illnesses of father: High blood pressure 0.3 0.3 1.1 0.4 0.8 0.6 0.5 -0.2 -0.3 1.1 0.5
Alcohol drinker status: Never 1.6 1.9 6.0 -2.4 -1.4 -0.9 0.6 -1.6 -1.2 -0.3 -1.4
Ever smoked 0.9 1.5 3.9 -1.0 -0.9 -2.0 -1.5 0.7 -0.7 -1.7 -0.6
Basal metabolic rate 0.8 4.4 22.3 -1.6 -1.1 -0.9 0.8 -2.2 -1.6 -0.5 -4.7
Leg fat percentage (left) 0.9 3.2 12.4 -0.5 2.9 3.5 0.2 1.8 0.8 0.6 -0.8
Arm fat-free mass (left) 0.9 4.4 18.9 -1.8 -1.0 -0.8 1.7 -2.5 -1.3 -0.6 -4.3
Number of operations (self-reported) 0.3 0.4 1.4 -0.2 -0.2 -0.4 -1.2 0.0 -0.6 -0.5 -1.0
Average weekly beer plus cider intake 1.9 2.7 6.6 2.4 2.2 1.3 0.1 2.6 0.4 0.2 1.5
Irritability 0.5 0.8 4.1 -0.0 -0.6 -0.7 -0.0 -2.0 0.2 -0.8 -0.7
Risk taking 0.3 0.4 1.1 -0.8 0.5 0.3 1.1 -0.2 0.9 -0.1 0.2
Ever had prostate specific antigen (PSA) test 2.6 3.0 7.4 -1.6 -1.2 -1.1 -0.7 0.4 -2.7 -1.7 -2.7
Fractured/broken bones in last 5 years 1.0 1.3 5.6 -1.2 0.8 0.3 2.4 0.6 0.4 1.0 1.0
Age started oral contraceptive pill 0.6 0.7 3.0 -1.7 -0.3 -0.6 0.6 -0.6 1.2 -0.1 0.3
Diastolic blood pressure, automated reading 0.4 1.3 3.0 -1.6 0.5 1.3 -1.7 -0.1 1.7 -0.5 -0.3
Ever depressed for a whole week 0.8 1.0 3.2 0.1 -1.3 -0.6 -0.1 -0.3 -1.4 -1.8 -0.8
Unable to work because of sickness or disability 0.5 0.7 2.9 0.4 0.4 0.7 1.7 -0.1 0.5 0.2 1.2
Commuting to job workplace: Cycle 0.6 0.8 1.5 0.0 0.4 1.0 -0.9 1.2 1.2 -0.3 1.0
Myopia 2.0 2.9 10.6 1.2 -0.2 -0.5 -0.4 1.8 -2.4 -1.4 -3.3
Vascular/heart problems diagnosed by doctor 0.2 0.7 2.1 -1.2 0.5 0.1 0.2 -0.9 0.9 1.4 0.2
Cholesterol lowering medication 0.7 1.1 2.2 -1.1 1.5 1.4 0.4 1.1 1.1 -0.1 0.5
Medication: Omeprazole (e.g. Zanprol) 0.7 0.9 2.1 0.2 -1.0 -0.9 1.4 -0.3 -1.0 1.5 0.4
Pain experienced in last month 0.6 1.0 3.1 -1.0 0.8 1.3 -1.8 0.2 0.2 -0.4 1.0
Supplements: Calcium 0.2 0.2 0.8 0.1 0.0 -0.9 0.3 0.9 -0.1 0.0 -0.6
Basal cell carcinoma (self-reported) 0.2 0.3 0.9 -0.3 -0.5 -0.2 -1.0 -0.2 -0.1 0.5 -0.7
Heart attack/myocardial infarction (self-reported) 0.1 0.1 0.3 -0.4 0.1 -0.3 0.5 0.4 0.2 0.4 0.4
Deep venous thrombosis (DVT) (self-reported) 0.4 0.5 2.4 1.0 -0.4 0.1 1.5 0.1 0.3 0.3 0.5
Heart disease (siblings) 0.3 0.3 1.9 0.4 -0.1 0.2 1.4 0.4 0.1 -0.2 0.6
Alcohol drinker status: Previous 0.5 0.6 2.0 -0.3 -0.6 -1.4 -0.5 -1.3 0.2 -0.5 -0.2
Pack years of smoking 1.2 1.8 4.0 2.0 -1.2 -1.2 -0.7 -0.7 -1.4 -1.2 -1.8
Impedance of whole body 0.6 3.1 10.6 -0.5 1.8 1.4 0.4 1.2 1.8 2.1 3.3
Leg fat mass (left) 0.5 1.8 5.0 -0.6 1.7 2.2 0.2 1.2 -0.4 0.5 -2.0
Arm predicted mass (left) 0.9 4.4 20.2 -1.8 -1.0 -0.6 1.4 -2.4 -1.4 -0.6 -4.5