Hub : Genes

LIAS

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1480	0.0620	4.1e-03	0.040	0.020	0.060	0.102	0.028	1.0e-05	1.4e-03	7.8e-08	2.0e-12	2.0e-04
2	GTEx	Breast Mammary Tissue	0.2290	0.0720	1.4e-03	0.048	NA	0.104	NA	0.067	1.8e-03	NA	5.1e-06	NA	2.6e-04
3	GTEx	Breast Mammary Tissue (Female)	0.2734	0.0987	1.1e-02	0.083	NA	0.151	NA	0.054	1.8e-03	NA	2.9e-05	NA	1.0e-02
4	METSIM	Adipose	0.0882	0.0290	3.3e-06	0.003	0.031	0.025	0.030	0.023	1.1e-01	1.6e-05	1.1e-04	2.5e-05	1.6e-04
5	YFS	Blood	0.4136	0.0420	0.0e+00	0.290	0.333	0.347	0.351	0.338	5.2e-96	3.9e-113	5.7e-119	1.0e-120	2.4e-115
6	TCGA	Head and Neck Squamous Cell Carcinoma	0.0650	0.0259	1.1e-05	0.053	0.051	0.034	NA	0.035	1.3e-06	2.1e-06	8.5e-05	NA	7.8e-05
7	TCGA	Pancreatic Adenocarcinoma	0.1810	0.0730	1.5e-03	-0.003	0.088	0.060	NA	0.019	4.3e-01	1.6e-04	1.6e-03	NA	5.0e-02
8	TCGA	Thyroid Carcinoma	0.1010	0.0470	9.2e-06	0.035	0.052	0.027	NA	0.034	2.4e-04	8.1e-06	1.2e-03	NA	2.8e-04

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	1.5	2.4	8.7	-1.2	-0.9	-0.6	0.3	-1.3	-1.9	-1.5	-2.9
Bipolar Disorder or Schizophrenia	0.8	2.1	10.3	0.0	-0.8	-0.9	0.2	-0.9	-1.4	-1.4	-3.2
Depressed Affect (Nagel 2018)	1.3	2.7	8.5	-1.5	-0.9	-1.7	2.2	-2.9	0.1	-0.9	-1.0
Depression (Nagel 2018)	0.6	0.8	3.1	-1.2	-0.3	-0.9	0.5	-1.8	0.5	-0.4	-0.8
Intelligence (Savage-Jansen 2018)	1.0	3.1	14.6	-1.7	-1.5	-1.2	-1.3	-3.8	-0.4	-0.8	-1.2
Neuroticism (Nagel 2018)	1.0	2.3	9.2	-1.5	-0.1	-0.6	2.1	-3.0	0.6	-0.0	-1.4
Schizophrenia (2018)	0.3	0.6	3.0	1.0	-0.3	-0.7	-0.1	-0.1	-0.2	-0.6	-1.7
Schizophrenia vs Biploar Disorder	0.8	1.0	3.7	1.9	-0.7	-0.4	-0.5	0.6	1.1	-1.2	0.8
Worry (Nagel 2018)	0.5	1.0	2.5	1.0	-0.6	-0.9	0.5	-1.6	-0.6	-0.6	-1.6
Alzheimer’s Disease (in mother)	0.9	1.1	3.3	0.7	1.3	1.0	0.3	1.2	0.7	0.6	1.8
Alzheimer’s Disease (in father)	1.1	1.2	3.1	-0.5	1.8	1.5	0.5	0.8	0.4	1.5	0.5
Alzheimer’s Disease (including proxy)	1.4	2.0	5.2	0.7	1.6	1.6	-0.2	2.0	0.5	0.9	2.3
Crohns Disease (2017)	2.1	4.6	11.6	-1.0	2.4	2.6	0.4	-0.6	3.4	0.7	3.2
Irritable Bowel Disease (IBD)	1.8	4.2	12.7	-0.5	2.0	2.3	0.2	-0.0	3.6	0.4	3.4
Ulcerative Colitis (UC)	0.7	1.3	4.6	0.8	0.4	1.0	-0.2	0.5	1.9	-0.6	2.1
Major Depression (MDD)	0.9	1.1	4.2	-2.1	-0.3	-0.9	0.7	-0.5	-1.3	-0.8	-0.9
Reaction Time	0.7	1.4	4.7	2.2	-1.5	-1.0	-0.2	0.9	-1.4	-0.7	0.2
Verbal and Numeric Reasoning (VNR)	1.2	2.8	13.5	0.4	-1.3	-0.6	-1.6	-3.7	-0.3	-1.7	-0.9
Breast Cancer	0.5	1.1	3.4	0.4	-0.2	-1.3	-1.1	1.8	-1.2	0.8	-0.6
Ovarian Cancer	1.2	1.6	3.7	-1.3	1.1	1.5	0.4	-0.1	0.6	1.9	1.7
Prostate Cancer	1.0	1.4	6.3	-2.5	-0.2	0.5	1.2	-0.8	0.4	1.3	-0.6
Age at First Birth	0.6	0.9	3.1	-1.1	-0.9	-0.7	-1.8	-0.3	0.1	-1.2	-0.5
Bipolar Disorder (2011)	0.5	0.5	3.4	-0.8	-0.2	-0.1	-0.1	-1.8	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.2	0.3	1.3	1.1	0.0	0.1	-0.2	-0.3	0.7	0.1	0.6
Coronary Artery Disease (CAD)	1.9	2.3	4.9	-2.2	1.3	1.2	1.7	-0.2	1.9	0.6	1.7
Crohns Disease (2012)	2.0	3.2	9.5	-1.1	1.4	1.5	1.0	-1.1	3.1	-0.3	2.8
Mean Putamen Volume	0.7	0.8	2.6	0.1	-1.2	-1.6	0.5	-0.8	-0.7	-0.8	-0.8
Fasting Glucose	0.6	0.7	1.9	0.9	1.0	1.4	0.3	-0.5	0.5	-1.2	0.3
HbA1C	0.3	0.3	0.6	-0.8	-0.3	-0.1	0.7	-0.3	0.7	0.6	-0.2
HDL Cholesterol	1.3	2.1	7.1	0.2	1.4	1.3	0.6	2.0	-0.9	2.7	-1.1
LDL Cholesterol	1.2	1.9	3.5	-0.8	1.9	1.9	-1.0	1.3	1.1	-1.3	1.3
Lupus	0.6	0.9	2.8	1.4	0.5	-0.1	-1.7	-0.9	1.1	-0.4	0.1
Neuroticism (2016)	0.7	1.0	6.3	-0.1	0.8	0.3	2.5	-0.8	0.8	-0.2	-0.2
Primary Biliary Cirrhosis	0.3	0.4	1.2	-0.7	0.2	0.5	0.8	-0.7	1.1	0.6	0.0
Rheumatoid Arthritis	0.7	1.0	4.1	-1.5	-0.0	0.3	-2.0	-0.6	-0.3	0.2	0.8
Schizophrenia (2014)	0.3	0.7	2.6	1.2	-0.3	-0.6	-0.2	-0.1	-0.3	-1.0	-1.6
Triglycerides	1.0	1.6	5.5	1.3	-1.4	-1.1	-0.4	-0.4	-1.5	-2.4	0.2
Type 2 Diabetes (T2D) (2012)	0.5	0.5	2.2	1.5	-0.7	-0.0	0.6	-0.5	-0.5	-0.6	0.7
Ulcerative Colitis	0.7	1.1	4.2	0.8	0.3	-0.0	0.4	0.1	1.1	-2.0	1.4
Blood Eosinophil Count	0.5	4.2	10.0	0.8	-2.5	-1.4	-2.6	-1.1	-2.5	0.1	-3.2
Blood Platelet Count	0.6	6.7	10.2	-2.6	2.6	2.9	3.2	-0.3	2.9	1.9	3.1
Blood Red Count	0.5	4.9	10.6	-2.0	-2.6	-1.5	-0.9	-3.3	-1.7	-1.4	-3.1
Blood White Count	0.3	1.9	4.7	1.1	-1.0	-0.5	0.5	2.2	-1.8	0.3	2.0
Heel T-Score	1.0	8.3	26.1	1.4	-2.5	-1.6	-5.1	-2.9	-0.3	-4.5	-1.0
BMI	0.3	2.0	4.5	0.3	1.0	1.8	-1.2	2.1	-1.4	0.4	-1.8
Height	0.8	14.5	34.5	-4.9	-0.5	-0.8	5.9	-5.5	-0.3	2.1	-4.7
Waist Hip Ratio (WHR)	0.2	1.0	5.3	2.3	0.8	1.0	0.2	0.2	0.6	0.8	0.1
Systolic Blood Pressure	0.6	3.0	7.6	2.3	-0.1	1.3	-2.8	1.4	0.7	-1.5	2.2
Smoking Status	0.9	2.2	9.1	1.5	-1.2	-1.8	0.2	1.2	-3.0	0.1	-0.0
Allergy or Eczema	0.6	1.7	6.9	-2.6	-0.5	-0.9	0.0	-1.7	1.2	0.3	1.1
Cardiovascular Disease	0.3	0.8	3.1	0.7	0.4	1.0	0.0	0.9	0.9	-0.5	1.8
Hypothyroidism (self reported)	0.3	0.7	2.3	-0.5	1.0	0.6	-1.5	0.8	-0.3	0.1	-1.1
Respiratory disease	0.2	0.5	1.8	-0.1	0.6	-0.1	0.5	0.2	-0.1	1.3	1.2
Type 2 Diabetes (T2D) (2018)	0.3	0.6	1.8	0.9	0.0	0.1	0.4	0.6	-1.0	1.3	-0.8
Lung FEV1/FVC ratio	0.3	1.5	6.0	-0.8	-0.5	0.0	-1.1	-2.0	-0.5	-0.5	-2.4
Lung FVC	0.3	1.6	2.6	-1.1	-1.3	-1.1	1.1	1.0	-1.6	-1.6	0.9
Neuroticism	0.8	1.9	9.4	-0.7	-0.7	-0.9	1.4	-3.1	-0.4	-0.2	-1.4
Chronotype (morning person)	0.8	1.9	9.2	-3.0	1.3	1.7	0.1	-0.9	0.1	-0.3	-0.8
Hair Pigment	0.0	0.1	0.5	0.3	0.5	-0.1	0.3	0.1	0.3	-0.7	-0.0
Tanning	0.1	1.3	6.6	-0.3	0.3	-0.2	1.0	-0.8	1.4	0.4	2.6
Hand grip strength (left)	1.6	4.1	11.9	-1.0	-3.5	-3.1	-0.4	-1.2	-2.1	-1.9	-0.4
Number of treatments/medications taken	0.1	0.3	1.0	-0.1	-0.7	-0.2	-1.0	-0.7	-0.3	-0.1	-0.2
Average weekly spirits intake	0.7	0.9	3.9	-0.9	1.0	0.9	-0.5	0.7	-0.0	2.0	0.4
Sensitivity / hurt feelings	0.7	1.2	4.2	-1.2	0.6	0.2	0.2	-2.1	1.8	-0.0	-0.2
Frequency of depressed mood in last 2 weeks	0.3	0.5	1.2	-0.7	-0.4	-0.5	-0.2	-1.1	-0.1	-1.0	-0.8
Hearing difficulty/problems: Yes	0.4	0.6	2.7	0.2	-0.2	-0.0	0.2	-0.1	-1.3	-0.2	-1.6
Relative age of first facial hair	0.5	1.1	3.8	-0.3	2.0	1.6	0.6	1.3	0.4	0.1	0.2
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	3.7	-0.2	-0.8	-0.6	-0.9	0.3	-0.6	-0.7	-1.9
Ever used hormone-replacement therapy (HRT)	0.4	0.5	1.2	-0.2	-0.1	0.7	1.1	0.1	0.9	0.6	1.0
Ever had hysterectomy (womb removed)	1.2	1.4	3.2	0.2	1.1	0.9	1.7	-0.9	1.8	1.4	0.3
Systolic blood pressure, automated reading	0.5	1.5	8.4	0.3	-0.0	0.8	-2.9	0.5	0.9	-1.2	0.2
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	3.6	0.4	1.2	1.1	1.9	-0.0	1.4	0.4	0.6
Angina	2.0	2.6	7.2	-1.4	1.2	0.3	2.1	2.0	-0.2	1.1	2.7
Medication for hormone replacement therapy	1.2	1.3	7.0	0.7	-0.5	-0.7	-2.6	0.7	0.1	-1.3	-0.3
Vitamin and mineral supplements	0.4	0.5	1.1	0.5	0.6	0.1	0.9	1.1	-1.1	-0.4	0.1
Supplements: Zinc	0.7	0.8	2.3	-1.1	0.9	0.5	0.9	0.2	0.5	1.5	-0.7
Medication: Co-codamol	0.4	0.4	1.0	-0.9	-0.6	-0.9	0.3	-0.4	-0.4	-1.0	-0.4
Medication: Metformin	0.6	0.8	4.1	0.1	-1.0	-0.5	0.1	0.7	-2.0	0.2	-0.8
Diabetes (father)	0.6	0.7	2.1	1.4	-0.4	-1.1	-0.4	-0.7	0.6	0.8	0.8
Diabetes (mother)	0.8	1.1	4.0	0.2	-0.8	-0.2	-0.6	-0.0	-2.0	-1.0	-1.6
Severe depression (siblings)	0.8	0.9	2.4	1.5	-0.6	-0.3	0.3	-0.2	-1.0	-1.5	-0.9
Pack years adult smoking proportion	1.3	2.0	4.0	2.0	-1.4	-1.4	-0.7	-0.8	-1.7	-1.2	-1.5
Impedance of leg (right)	1.1	5.4	19.1	-0.9	2.3	1.7	1.9	0.9	2.4	2.3	4.4
Leg fat-free mass (left)	0.8	4.1	22.8	-0.9	-1.2	-1.0	-0.2	-1.7	-1.9	-0.4	-4.8
Trunk fat percentage	1.0	4.1	12.2	-1.1	3.1	3.5	-0.3	2.0	0.3	1.9	-1.5
Hand grip strength (right)	2.2	5.9	13.8	-0.9	-3.7	-3.7	-0.9	-2.2	-2.5	-2.3	-1.1
Townsend deprivation index at recruitment	0.2	0.2	0.7	0.8	0.2	-0.3	0.2	0.4	-0.4	-0.1	-0.7
Current tobacco smoking	1.0	1.7	5.1	0.6	-1.0	-2.2	-0.9	-0.0	-2.3	-0.7	-1.0
Average weekly fortified wine intake	1.0	1.1	4.3	1.4	-0.8	-0.4	-0.0	-2.1	0.5	-0.9	-1.0
Maternal smoking around birth	1.8	2.6	5.7	2.3	1.7	1.0	1.8	0.8	0.0	1.5	2.4
Fed-up feelings	0.7	1.3	3.2	-0.6	-0.8	-1.7	0.7	-1.8	-1.0	-0.7	-1.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	1.6	-0.6	-0.0	-1.1	-0.2	-1.2	-0.7	-1.2	-1.0
Relative age voice broke	1.1	1.7	5.0	-0.4	2.2	2.0	0.7	1.4	1.2	0.5	0.2
Taking other prescription medications	0.3	0.5	1.2	-1.1	0.6	0.2	0.4	-0.1	-0.9	0.9	-0.8
Age when periods started (menarche)	0.2	0.6	1.9	1.4	-0.4	-0.6	-0.1	-0.5	-0.6	-0.2	-1.3
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	2.0	0.5	-0.4	-0.5	1.0	-0.7	0.7	-1.4	0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.2	3.6	0.4	-0.6	0.7	-0.3	-1.9	1.1	-1.7	0.6
Tinnitus: Yes, but not now, but have in the past	1.0	1.0	2.9	1.1	0.9	0.8	-0.1	1.7	-1.4	0.8	0.3
Qualifications: CSEs or equivalent	0.9	1.2	6.2	-0.1	0.2	0.3	0.2	-2.5	1.5	-0.4	0.8
Serious illness, injury or assault to yourself	0.7	0.9	2.0	0.8	0.3	1.4	-0.8	1.4	-0.9	0.8	0.3
High blood pressure	0.3	0.9	3.7	0.4	-1.0	-0.5	-0.7	-0.1	-1.0	-1.9	-0.9
Hayfever, allergic rhinitis or eczema	0.7	1.5	6.2	-2.5	-0.8	-1.2	-0.4	-1.7	-0.0	0.3	0.8
Multivitamins +/- minerals	0.4	0.5	2.7	-0.2	-0.4	-0.1	-0.3	-0.7	1.6	0.3	-0.0
Stomach or abdominal pain in last month	0.3	0.3	0.8	0.3	-0.7	-0.9	0.8	-0.6	0.2	0.2	0.3
Supplements: Glucosamine	0.7	1.0	4.1	-0.6	0.1	-0.0	-2.0	-0.7	-0.8	-1.1	-0.9
Diverticular disease/diverticulitis (self-reported)	1.4	1.7	4.4	1.6	-1.6	-0.9	0.3	-1.3	1.0	-0.7	2.1
Medication: Atenolol	0.8	1.0	2.8	0.6	0.9	1.2	0.6	1.4	-0.2	-0.2	1.7
Medication: Levothyroxine sodium	0.4	0.7	2.7	-1.1	0.7	0.7	-1.7	0.3	0.2	0.0	-0.8
Sitting height	0.3	2.3	7.6	-1.6	0.1	-0.0	2.8	-1.7	-0.3	1.9	-1.4
Chronic bronchitis/emphysema (father)	1.7	2.0	4.4	1.2	-2.1	-1.8	-1.9	0.2	-1.4	-1.1	0.3
High blood pressure (mother)	0.7	0.9	5.6	2.4	-0.1	-0.0	-0.3	-0.7	-0.6	0.9	0.4
Body mass index (BMI)	0.4	1.6	6.0	-0.3	1.3	1.9	-0.6	0.8	-0.5	0.1	-2.5
Impedance of leg (left)	1.0	5.0	17.8	-1.2	2.0	1.7	2.0	0.8	2.5	1.8	4.2
Leg predicted mass (left)	0.8	4.2	23.5	-1.0	-1.2	-1.0	-0.2	-1.7	-1.9	-0.5	-4.8
Trunk fat mass	0.7	3.0	7.4	-1.3	2.3	2.7	-0.0	1.2	-0.2	1.4	-2.4
Waist circumference	0.6	2.0	9.6	0.1	1.3	1.9	-0.1	0.1	-0.8	0.5	-3.1
Number of incorrect matches in round	1.3	2.1	7.3	-0.7	2.0	0.8	0.9	2.7	-1.4	1.2	-0.6
Past tobacco smoking	0.3	0.6	2.1	0.1	0.2	0.9	0.0	-1.4	1.2	0.3	0.1
Alcohol usually taken with meals	0.8	1.3	3.8	-2.0	-1.4	-0.8	-1.1	-0.7	0.2	-1.0	0.9
Nervous feelings	0.3	0.5	1.2	0.8	-0.5	-0.7	0.9	-1.1	0.1	-0.1	-0.5
Frequency of tenseness / restlessness in last 2 weeks	1.0	1.6	3.5	0.4	-1.3	-1.9	-0.5	-0.9	-1.6	-1.7	-0.9
Hearing difficulty/problems with background noise	0.7	1.1	3.8	0.6	0.3	0.8	0.4	0.6	-2.0	0.8	-1.7
Hair/balding pattern: Pattern 2	1.0	1.3	3.0	-1.7	-0.1	0.7	1.3	-1.0	1.3	-0.3	1.5
Had menopause	0.5	0.6	2.7	-0.5	0.0	1.0	0.7	-0.4	1.7	0.4	0.4
Had other major operations	0.7	0.8	2.9	0.0	1.2	0.7	-0.7	-0.1	1.7	1.1	-0.3
Forced vital capacity (FVC)	0.2	0.9	2.1	-0.4	-1.5	-1.1	1.2	-0.3	-1.1	-0.7	0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.6	4.4	0.0	-0.2	0.9	-0.4	-2.1	2.0	-1.9	-0.0
Ever unenthusiastic/disinterested for a whole week	1.6	2.0	5.1	-1.6	-2.3	-1.5	0.2	-1.1	-1.2	-1.4	-1.1
Qualifications: None of the above	0.5	1.1	3.0	-0.3	1.6	0.5	1.7	0.8	-0.2	1.3	-0.6
Financial difficulties in last 2 years	0.7	0.9	3.1	0.3	-0.2	-0.9	-0.5	1.4	-0.8	-0.8	-1.8
Mouth/teeth dental problems	0.4	0.6	1.1	0.8	-0.6	-1.0	1.0	1.0	0.2	1.0	0.4
Heart attack	0.1	0.2	0.5	-0.0	0.2	-0.0	0.7	0.3	0.3	0.5	0.5
Allergy	0.6	1.3	7.1	2.7	0.7	0.9	0.3	0.9	0.8	-0.4	-0.5
Pain all over the body in last month	0.3	0.3	1.4	0.4	-0.0	-0.4	0.4	-0.1	-0.6	0.3	-1.2
Diabetes (self-reported)	0.3	0.4	1.2	-0.0	0.8	1.0	0.3	0.5	0.1	1.1	-0.2
Hayfever/allergic rhinitis (self-reported)	0.9	1.1	3.7	-0.9	0.7	-0.3	0.4	-0.9	1.4	1.9	1.1
Medication: Ramipril	0.8	1.1	3.1	1.7	0.1	0.9	-0.8	1.0	-0.8	-1.2	-0.9
Medication: Simvastatin	0.5	0.7	1.9	0.4	1.1	1.2	0.3	-0.0	1.4	-0.8	0.4
Fluid intelligence score	0.3	0.7	3.1	0.2	-0.4	0.4	-0.7	-1.8	-0.0	-1.1	-0.8
Illnesses of siblings	0.5	0.7	3.5	-1.9	1.1	-0.0	-0.1	-0.7	0.6	-0.1	-0.6
Neuroticism score	0.9	1.8	5.4	0.1	-1.3	-1.8	0.4	-2.3	-1.0	-1.0	-1.4
Weight	0.6	2.9	16.6	-1.8	0.3	0.8	0.5	-1.0	-1.2	0.4	-4.1
Impedance of arm (right)	0.3	1.2	3.6	-0.5	0.7	0.2	-1.2	0.7	1.0	1.6	1.9
Arm fat percentage (right)	0.7	2.8	7.1	-0.3	2.2	2.7	-1.4	1.9	-0.4	0.9	-2.0
Trunk fat-free mass	1.0	5.9	21.2	-2.0	-1.9	-1.9	1.3	-3.1	-1.8	-0.8	-4.6
Hip circumference	0.4	1.6	9.4	-0.7	0.7	1.1	0.0	0.2	-1.1	0.5	-3.1
Time employed in main current job	0.8	0.9	1.7	-1.1	-0.8	-1.3	-1.0	-0.2	-1.3	-0.2	-0.9
Alcohol intake versus 10 years previously	1.1	1.6	5.7	-0.2	-0.3	-0.5	1.0	-0.8	-2.0	1.1	-2.4
Father’s age at death	0.6	0.8	2.6	0.5	0.8	0.4	0.8	-1.6	0.6	1.1	-0.5
Worrier / anxious feelings	0.3	0.6	2.5	-0.9	0.1	0.1	-0.0	-1.6	0.4	-0.9	-0.5
Frequency of tiredness / lethargy in last 2 weeks	1.2	2.0	7.2	-0.3	0.2	-1.0	-0.1	-2.6	0.8	-0.7	-2.7
Falls in the last year	0.4	0.5	1.4	-1.1	0.1	0.0	-0.1	-0.8	-0.4	-1.2	-0.7
Hair/balding pattern: Pattern 3	0.5	0.8	3.1	0.1	-0.5	-0.8	-0.7	1.0	0.6	-0.5	1.8
Number of live births	0.5	0.7	2.1	1.1	-0.1	0.6	0.3	0.6	0.3	1.3	1.4
Forced expiratory volume in 1-second (FEV1)	0.2	0.8	1.5	-0.9	-1.1	-0.7	1.2	-1.1	-0.8	-0.3	-0.2
Pulse rate	0.1	0.1	0.4	-0.2	0.0	-0.1	-0.7	-0.5	-0.3	0.3	-0.1
Happiness	0.9	1.1	3.8	-1.0	-0.5	0.3	-1.5	-0.4	-1.0	-0.6	-1.9
Noisy workplace	1.4	1.7	3.4	1.9	-1.5	-0.8	-1.4	1.1	-1.5	-0.6	1.4
Qualifications: A levels/AS levels or equivalent	1.0	2.3	4.4	-0.8	-2.0	-1.2	-2.1	-1.3	-0.9	-1.7	-1.6
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.5	-0.1	0.3	0.5	0.3	-0.3	0.7	-0.2	0.2
Mouth/teeth dental problems: Dentures	1.3	2.2	4.8	-0.7	2.2	2.2	0.9	-0.0	1.8	0.1	1.9
Asthma	0.1	0.2	0.5	-0.6	-0.0	0.0	0.7	-0.3	-0.4	0.7	0.3
Medication: Ibuprofen (e.g. Nurofen)	3.0	3.8	7.0	-1.9	-2.0	-2.1	-0.8	-1.0	-2.6	-1.8	-2.6
Medication: Cholesterol lowering	0.3	0.5	1.7	0.8	0.2	0.8	-0.0	-0.2	1.0	0.2	1.3
Depression (self-reported)	3.2	3.8	7.0	-1.6	-2.2	-2.4	-0.4	-1.9	-1.7	-2.6	-1.9
Medication: Lansoprazole	0.4	0.4	1.4	-0.7	0.2	-0.1	0.5	0.5	-0.9	1.2	0.4
Prospective memory result	0.9	1.2	3.8	-1.5	-0.5	-1.3	-0.4	0.9	-1.9	0.2	-0.6
Lung cancer (father)	0.4	0.5	1.9	-0.6	0.3	0.2	0.1	-0.4	0.1	1.2	-1.4
Illnesses of mother	0.8	1.0	2.7	-0.8	-1.0	-0.5	-0.1	-1.1	0.2	-1.4	-1.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.8	2.6	0.5	-0.9	-0.9	1.6	-1.1	-0.7	-0.2	-0.7
Pulse wave Arterial Stiffness index	0.4	0.5	1.6	-0.6	-0.8	-0.2	-1.1	-0.0	-0.5	-1.2	0.1
Impedance of arm (left)	0.4	1.6	3.7	0.2	1.0	0.7	-1.4	1.2	1.0	1.8	1.9
Arm fat mass (right)	0.5	2.1	8.9	-0.8	1.3	1.8	-0.5	0.9	-0.9	0.5	-3.0
Trunk predicted mass	1.1	6.0	21.6	-1.9	-2.0	-1.9	1.3	-3.1	-1.8	-0.9	-4.7
Standing height	0.8	8.0	16.4	-3.5	-2.1	-2.6	2.4	-4.0	-1.6	0.5	-4.0
Length of working week for main job	0.5	0.5	2.5	-0.4	0.1	-0.3	1.6	0.3	0.4	0.7	0.8
Exposure to tobacco smoke at home	1.4	1.6	4.0	-1.7	1.4	0.9	1.5	-0.2	0.4	2.0	0.7
Breastfed as a baby	2.3	2.8	7.4	2.7	-1.3	-0.6	-2.6	-0.7	1.3	-2.0	-0.3
Tense / ‘highly strung’	0.4	0.7	3.4	0.3	0.5	-0.4	-0.2	-0.3	-0.7	-0.9	-1.9
Seen doctor (GP) for nerves, anxiety, tension or depression	1.8	2.8	10.9	-3.3	-0.5	-0.7	0.2	-3.0	0.2	0.2	-1.5
Hair/balding pattern: Pattern 4	1.0	2.3	10.7	0.5	1.0	0.1	0.7	0.0	-1.2	2.2	-3.3
Birth weight of first child	0.7	1.3	3.0	-1.5	0.3	-0.3	1.7	-1.4	1.1	1.2	0.0
Peak expiratory flow (PEF)	0.4	0.9	3.8	0.6	-1.1	-1.1	-0.3	-0.2	-1.9	0.2	-0.4
Pulse wave reflection index	0.6	0.8	3.1	1.8	0.3	0.9	-0.9	1.1	-0.1	-0.2	-0.3
Ever highly irritable/argumentative for 2 days	1.8	2.2	7.1	1.5	-1.8	-1.7	1.0	0.8	-2.7	-0.5	-0.0
Loud music exposure frequency	0.9	1.0	3.1	-0.7	-1.3	-1.4	-0.0	-1.8	-0.7	0.4	-0.4
Qualifications: O levels/GCSEs or equivalent	0.8	1.2	2.6	1.1	-1.1	-1.1	-1.6	-0.9	0.7	-1.5	-0.1
Mouth/teeth dental problems: Bleeding gums	0.9	1.1	4.6	0.4	-0.7	0.0	-2.1	-0.7	-0.7	-1.4	-0.8
Blood clot in the leg (DVT)	0.4	0.5	2.4	0.9	-0.2	0.1	1.6	0.2	0.5	0.5	0.5
Medication: Paracetamol	0.8	1.4	5.6	-2.4	-0.4	-1.3	1.0	-0.8	-0.4	0.8	-1.1
Headache pain in last month	0.9	1.6	5.5	-1.1	-1.4	-2.4	1.0	-1.3	-0.5	-0.3	-1.0
Medication for cholesterol, blood pressure or diabetes	0.8	1.4	3.0	-1.0	1.6	0.6	1.5	-0.6	1.0	1.7	-0.7
Glaucoma (self-reported)	1.0	1.2	2.7	0.9	1.4	1.5	0.3	-0.5	0.3	1.6	-1.2
Gout (self-reported)	1.5	2.1	4.2	0.6	1.5	1.3	1.1	1.4	1.2	2.1	1.9
Hypothyroidism/myxoedema (self-reported)	0.6	1.2	3.4	-1.8	1.1	1.2	-1.3	0.6	-0.2	-0.2	-1.2
Medication: Amlodipine	0.5	0.6	2.0	-0.2	-0.8	-0.5	0.4	-0.1	-1.4	-1.4	-0.1
Medication: Ventolin 100micrograms inhaler	0.3	0.3	1.0	-0.2	-0.6	-1.0	-0.4	-0.1	-0.9	0.1	0.4
Birth weight	0.7	1.5	8.1	0.2	-0.2	-0.8	2.9	0.1	0.1	1.7	0.2
Chronic bronchitis/emphysema (mother)	1.4	1.6	5.4	-0.5	1.0	0.5	1.3	0.5	1.0	2.3	1.7
High blood pressure (siblings)	1.1	1.6	7.6	2.8	-1.4	-0.1	-0.9	0.2	-0.4	-1.1	0.8
Forced vital capacity (FVC), Best measure	0.2	0.9	4.0	0.6	-1.0	-1.0	2.0	-0.5	-0.6	-0.4	0.1
Body fat percentage	1.1	4.2	14.1	-0.7	3.2	3.8	-0.3	2.2	0.5	1.6	-1.1
Leg fat percentage (right)	1.0	3.5	12.4	-0.5	3.1	3.5	0.1	2.0	0.7	1.0	-0.6
Arm fat-free mass (right)	0.7	3.6	15.9	-1.5	-0.9	-0.5	1.6	-2.4	-1.1	-0.6	-4.0
Exposure to tobacco smoke outside home	0.3	0.4	1.4	1.2	0.4	-0.1	-1.1	-0.2	0.2	-0.2	0.1
Comparative body size at age 10	1.2	3.2	7.7	2.6	-1.6	-1.6	0.1	0.4	-2.8	-1.0	-2.2
Number of full brothers	0.3	0.4	1.8	1.3	0.5	0.1	0.3	0.9	0.1	0.6	-0.5
Worry too long after embarrassment	0.4	0.6	1.4	0.0	-0.2	-0.4	0.9	-0.9	-1.1	0.7	-1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	1.3	1.7	5.7	-1.2	0.8	-0.2	2.4	-1.5	0.9	1.3	-1.0
Wheeze or whistling in the chest in last year	0.4	0.7	3.1	1.0	-0.8	-1.8	-0.4	-0.5	-0.7	-0.5	0.1
Number of children fathered	0.3	0.4	1.6	0.3	0.3	0.4	1.0	0.0	1.3	0.0	0.1
Reason for reducing amount of alcohol drunk: Health precaution	3.5	4.1	12.8	3.6	1.2	2.3	-0.3	1.8	1.2	0.1	2.9
Age at first live birth	0.2	0.4	1.7	0.2	0.2	0.1	-1.3	-0.6	1.0	0.6	0.3
Pulse wave peak to peak time	0.4	0.5	1.4	0.3	0.7	0.0	1.2	-0.4	0.4	1.1	-0.4
Health satisfaction	1.9	2.5	6.5	2.5	0.9	1.3	0.7	2.5	-1.3	1.0	1.1
Shortness of breath walking on level ground	1.0	1.2	3.5	-0.4	1.3	0.5	1.0	1.4	0.9	1.9	0.4
Qualifications: College or University degree	0.3	1.1	3.3	-0.2	-1.7	-0.6	-1.8	-1.3	0.3	0.0	0.5
Eye problems/disorders: None of the above	0.3	0.3	0.8	0.6	-0.8	-0.1	0.2	-0.2	0.2	-0.9	0.8
Mouth/teeth dental problems: Loose teeth	1.6	1.9	5.6	2.4	-0.2	0.2	-0.8	1.3	-1.9	-0.7	-1.7
Emphysema/chronic bronchitis	1.4	1.5	2.3	0.9	-1.5	-1.4	-0.8	-1.5	-1.4	-1.3	-0.9
Medication for pain relief, constipation, heartburn	1.2	2.0	6.1	1.6	0.5	1.1	-1.4	0.2	2.5	-0.9	1.7
Neck or shoulder pain in last month	0.4	0.6	2.4	0.6	0.2	-0.3	1.5	1.1	-0.6	0.5	0.2
Medication: Blood pressure	1.3	2.2	3.5	1.7	-1.4	-0.2	-1.5	1.7	-1.9	-1.9	0.9
Angina (self-reported)	2.1	2.7	7.3	-1.4	1.4	0.3	2.1	2.0	0.0	1.4	2.7
Migraine (self-reported)	0.3	0.4	1.7	0.2	0.2	-0.3	0.7	-0.0	-0.2	1.0	1.3
Medication: Ibuprofen	4.4	5.3	9.3	-0.5	-3.0	-2.7	-1.2	-1.8	-2.7	-3.0	-2.2
Medication: Allopurinol	1.8	2.4	4.4	0.1	1.7	1.5	1.1	1.5	1.4	2.1	2.0
Medication: Omeprazole	0.5	0.5	1.6	0.2	-0.7	-0.8	1.2	-0.6	-0.4	1.0	-0.1
Medication: Seretide 50 evohaler	0.9	1.0	4.3	0.9	-0.6	-0.5	0.7	0.5	-0.6	1.1	2.1
Mean time to correctly identify matches	1.1	2.0	4.9	2.2	-1.6	-0.8	-0.5	1.4	-2.0	-1.2	-0.6
Heart disease (mother)	0.2	0.2	0.7	-0.2	0.5	0.4	0.8	0.1	0.1	0.6	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.8	2.1	8.5	2.9	-1.6	-0.6	-1.2	-0.6	-0.1	0.5	1.8
Whole body fat mass	0.6	2.5	6.4	-1.1	2.1	2.5	0.3	1.1	-0.2	1.3	-2.3
Leg fat mass (right)	0.5	1.9	5.1	-0.7	1.9	2.2	0.3	1.3	-0.4	0.8	-1.9
Arm predicted mass (right)	0.7	3.5	14.7	-1.4	-1.0	-0.6	1.7	-2.4	-1.3	-0.5	-3.8
Pulse rate, automated reading	0.7	2.4	6.2	-2.5	1.3	1.8	0.2	0.1	2.2	0.6	1.6
Alcohol intake frequency.	7.1	16.5	36.8	-5.3	-3.5	-4.9	-1.5	-3.8	-3.6	-0.7	-6.1
Comparative height size at age 10	1.0	5.7	15.2	-3.7	-1.6	-0.9	1.2	-2.1	-2.6	0.3	-3.9
Number of full sisters	1.9	2.3	4.8	1.3	1.6	2.2	2.1	0.7	1.0	1.4	1.2
Suffer from ‘nerves’	0.4	0.6	1.7	1.0	-0.5	-0.8	1.3	-0.7	-0.5	-0.3	0.3
Overall health rating	0.6	1.3	4.3	2.1	1.0	0.1	1.5	1.2	-0.4	1.1	-0.4
Chest pain or discomfort	0.3	0.4	1.2	1.1	0.4	-0.7	0.3	0.7	-0.6	0.7	-0.5
Had major operations	2.4	2.8	8.6	-2.9	-1.3	-1.7	-0.9	-0.5	-2.1	-1.5	-1.1
Age at last live birth	0.8	1.1	3.6	0.3	-0.2	0.1	-0.0	-1.8	1.9	0.5	1.3
Family relationship satisfaction	1.1	1.3	6.4	1.3	0.0	0.1	-1.1	0.5	-0.4	-0.8	-2.5
Leg pain on walking	0.7	0.9	3.9	0.5	-0.8	-0.3	-0.3	-0.8	-2.0	-1.0	-0.7
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	1.3	0.8	-0.2	-0.5	-0.1	0.4	-0.1	-1.1	0.8
Commuting to job workplace: Car/motor vehicle	0.4	0.4	1.1	-0.8	-0.9	-1.1	-0.4	-0.4	-0.7	0.5	0.0
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	3.3	1.8	0.4	0.2	-0.3	0.4	0.1	1.1	0.8
Medication: Aspirin	1.7	2.3	6.1	-1.3	2.0	2.0	1.1	1.1	0.3	2.5	0.3
Supplements: Vitamin C	0.4	0.5	1.9	-0.0	-0.1	0.5	-0.2	-1.4	0.9	0.6	0.6
Knee pain experienced in last month	0.7	1.0	4.7	1.0	0.3	-0.8	-0.3	-0.0	-1.2	-0.7	-2.2
Hypertension (Self-reported)	0.3	0.8	3.7	0.6	-1.0	-0.3	-0.5	-0.2	-0.8	-1.9	-0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.0	2.3	5.4	-0.4	-2.1	-1.5	0.1	-0.9	-2.3	-1.2	-2.1
Illnesses of father: Heart disease	0.3	0.3	1.2	-0.5	0.2	0.8	1.1	-0.3	-0.4	0.3	0.5
Illnesses of siblings: Diabetes	0.8	1.0	2.8	-0.1	-0.7	-0.6	1.6	1.7	-1.0	0.6	-0.2
Smoking status: Previous	0.6	0.9	3.7	0.1	0.9	0.8	0.9	1.9	-0.3	0.9	0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.5	2.1	0.4	-0.0	0.1	1.4	-1.2	0.6	0.0	-0.3
Whole body fat-free mass	0.9	5.2	23.3	-1.6	-1.6	-1.4	0.9	-2.6	-1.8	-0.7	-4.8
Leg fat-free mass (right)	1.0	5.1	25.8	-1.3	-1.6	-1.3	-0.3	-2.2	-1.9	-0.9	-5.1
Arm fat percentage (left)	0.8	3.0	8.9	0.1	2.3	3.0	-1.5	1.9	-0.2	1.0	-1.8
Average weekly red wine intake	0.6	0.9	3.6	0.6	-0.1	0.4	0.0	0.3	1.5	0.8	1.9
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.7	1.3	0.4	0.9	0.3	-0.2	0.9	0.8	-0.0
Mood swings	1.1	2.0	8.3	-1.0	-1.1	-1.5	0.5	-2.9	0.2	-1.5	-1.0
Loneliness, isolation	0.3	0.3	1.2	0.3	0.2	-1.1	1.0	-0.2	-0.3	-0.2	0.6
Long-standing illness, disability or infirmity	1.0	1.5	4.4	0.3	-1.7	-1.5	-0.4	-0.5	-2.1	-1.1	-1.0
Ever had bowel cancer screening	0.3	0.4	2.3	0.1	-0.3	0.1	-0.1	-0.7	0.1	-0.3	-1.5
Diabetes diagnosed by doctor	0.4	0.7	2.1	0.4	0.5	0.4	-0.0	1.5	-1.0	1.3	-0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.9	0.9	2.2	1.5	-1.4	-0.2	-0.7	-0.2	-0.7	-1.4	-0.2
Friendships satisfaction	1.5	1.9	3.7	1.6	-1.2	-0.8	-1.3	0.2	-1.1	-1.9	-1.9
Qualifications: nursing, teaching	0.1	0.1	0.4	0.6	-0.1	0.0	-0.1	-0.3	-0.2	0.6	0.1
Commuting to job workplace: Walk	0.2	0.2	0.7	-0.3	0.5	0.4	0.2	0.1	0.8	0.2	-0.6
Eye problems/disorders: Cataract	0.4	0.5	1.5	0.3	0.1	-1.0	-1.2	0.8	-0.2	0.7	-0.2
Mouth/teeth dental problems: Mouth ulcers	1.3	2.1	6.2	-2.5	-0.4	-0.6	-0.3	-2.4	-0.3	-0.5	-2.0
Medication for cholesterol	1.1	1.6	4.0	-2.0	-0.8	-1.4	1.6	-1.2	-1.0	1.1	-0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.1	5.7	-0.4	-0.4	-0.7	2.4	0.5	0.2	1.1	0.9
Back pain experienced in last month	0.3	0.5	2.4	0.0	-0.1	0.1	1.5	0.4	-0.9	0.3	-0.5
Mineral and other dietary supplements	0.1	0.2	0.6	-0.2	-0.6	-0.3	0.1	-0.3	-0.8	0.0	0.4
Breast cancer (self-reported)	1.3	1.5	4.0	0.4	1.6	1.1	0.9	-0.1	1.6	2.0	0.8
Asthma (self-reported)	0.2	0.4	1.0	-0.8	0.2	0.1	0.8	-0.3	-0.1	1.0	0.6
Osteoporosis (self-reported)	1.0	1.2	2.5	-1.0	-1.5	-1.6	-1.0	-0.4	-0.6	-1.4	0.2
Osteoarthritis (self-reported)	0.3	0.4	1.0	0.8	0.1	0.1	0.8	-1.0	-0.4	0.3	-0.8
Medication: Aspirin	1.5	2.0	5.7	-1.5	1.6	1.9	0.7	1.0	0.3	2.4	0.2
Medication: Gliclazide	0.2	0.2	0.6	0.8	-0.3	-0.2	0.7	-0.3	-0.6	-0.3	-0.1
Illnesses of father: None of the above (group 1)	0.4	0.5	1.5	0.1	1.2	0.7	-0.1	0.8	1.0	-0.1	-0.5
Smoking status: Current	0.8	1.3	3.9	0.9	-0.9	-2.0	-0.4	0.0	-2.0	-0.6	-0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.7	3.2	-0.3	0.4	1.0	1.8	0.5	-0.0	0.4	0.7
Whole body water mass	0.9	5.2	23.0	-1.6	-1.6	-1.4	0.8	-2.6	-1.8	-0.7	-4.8
Leg predicted mass (right)	1.0	5.1	25.6	-1.3	-1.6	-1.3	-0.3	-2.1	-1.9	-0.9	-5.1
Arm fat mass (left)	0.5	2.1	8.2	-0.8	1.4	1.9	-0.4	0.8	-0.7	0.6	-2.9
Number of self-reported non-cancer illnesses	0.2	0.4	1.0	0.4	-0.4	-1.0	-1.0	0.4	-0.4	-0.4	-0.8
Average weekly champagne plus white wine intake	0.6	0.8	2.7	-0.3	1.1	1.1	-0.0	-0.3	1.7	0.4	1.1
Miserableness	1.3	2.2	4.2	-1.6	-1.3	-2.0	1.6	-2.0	-1.1	-0.7	-0.9
Guilty feelings	1.6	2.4	5.7	-2.4	-1.7	-1.9	1.8	-1.2	-1.0	-0.6	-1.0
Wears glasses or contact lenses	1.0	1.2	2.8	-0.0	1.6	1.5	-1.2	1.7	0.0	0.6	0.1
Ever taken oral contraceptive pill	1.6	1.8	6.0	-0.1	-1.8	-1.4	0.2	1.8	-2.4	-0.5	-0.4
Hearing aid user	0.3	0.3	0.7	-0.2	0.4	0.7	-0.5	-0.8	0.8	0.6	0.0
Mother’s age at death	0.3	0.4	1.2	-0.2	-0.1	-0.6	0.5	-0.9	-0.0	-0.9	-1.1
Financial situation satisfaction	0.6	0.8	3.5	1.9	-0.2	-0.2	-0.9	1.1	-0.2	-0.6	0.6
Tinnitus: Yes, now most or all of the time	1.2	1.4	4.5	1.5	-1.3	-0.7	2.1	1.1	-0.8	0.5	0.6
Commuting to job workplace: Public transport	0.6	0.7	2.4	-1.5	-0.4	-0.9	-0.1	-1.1	-0.3	-1.0	-0.1
Eye problems/disorders: Glaucoma	0.6	0.7	1.5	0.2	1.1	1.2	0.3	-0.5	0.6	1.1	-0.9
Medication: Blood pressure	0.2	0.4	1.3	1.1	0.2	0.6	0.5	0.1	0.6	-0.8	0.3
Pain type(s) experienced in last month: Hip pain	0.5	0.6	1.7	1.3	-0.2	-1.3	-0.7	-0.3	-0.7	-0.3	-0.8
Supplements: Fish oil (including cod liver oil)	0.3	0.4	1.1	1.0	0.2	0.3	0.9	-0.1	1.0	-0.1	0.2
High cholesterol (Self-reported)	0.4	0.8	3.1	-0.7	-0.4	-0.1	-1.2	-0.1	0.2	-1.8	-0.9
Medication: Bendroflumethiazide	0.2	0.3	1.2	-0.4	-0.2	-0.0	-0.8	0.2	-0.0	-1.1	0.1
Medication: Paracetamol	1.0	1.5	6.2	-2.5	0.1	-1.1	0.7	-1.4	0.7	1.2	-0.6
Medication: Lisinopril	0.3	0.3	1.0	0.7	-0.4	0.2	0.3	0.4	-0.1	-1.0	0.7
Medication: Atorvastatin	0.4	0.5	1.0	-1.0	-0.4	-0.5	-0.8	0.9	-0.6	0.6	0.7
Illnesses of father: High blood pressure	0.3	0.3	1.1	0.4	0.8	0.6	0.5	-0.2	-0.3	1.1	0.5
Alcohol drinker status: Never	1.6	1.9	6.0	-2.4	-1.4	-0.9	0.6	-1.6	-1.2	-0.3	-1.4
Ever smoked	0.9	1.5	3.9	-1.0	-0.9	-2.0	-1.5	0.7	-0.7	-1.7	-0.6
Basal metabolic rate	0.8	4.4	22.3	-1.6	-1.1	-0.9	0.8	-2.2	-1.6	-0.5	-4.7
Leg fat percentage (left)	0.9	3.2	12.4	-0.5	2.9	3.5	0.2	1.8	0.8	0.6	-0.8
Arm fat-free mass (left)	0.9	4.4	18.9	-1.8	-1.0	-0.8	1.7	-2.5	-1.3	-0.6	-4.3
Number of operations (self-reported)	0.3	0.4	1.4	-0.2	-0.2	-0.4	-1.2	0.0	-0.6	-0.5	-1.0
Average weekly beer plus cider intake	1.9	2.7	6.6	2.4	2.2	1.3	0.1	2.6	0.4	0.2	1.5
Irritability	0.5	0.8	4.1	-0.0	-0.6	-0.7	-0.0	-2.0	0.2	-0.8	-0.7
Risk taking	0.3	0.4	1.1	-0.8	0.5	0.3	1.1	-0.2	0.9	-0.1	0.2
Ever had prostate specific antigen (PSA) test	2.6	3.0	7.4	-1.6	-1.2	-1.1	-0.7	0.4	-2.7	-1.7	-2.7
Fractured/broken bones in last 5 years	1.0	1.3	5.6	-1.2	0.8	0.3	2.4	0.6	0.4	1.0	1.0
Age started oral contraceptive pill	0.6	0.7	3.0	-1.7	-0.3	-0.6	0.6	-0.6	1.2	-0.1	0.3
Diastolic blood pressure, automated reading	0.4	1.3	3.0	-1.6	0.5	1.3	-1.7	-0.1	1.7	-0.5	-0.3
Ever depressed for a whole week	0.8	1.0	3.2	0.1	-1.3	-0.6	-0.1	-0.3	-1.4	-1.8	-0.8
Unable to work because of sickness or disability	0.5	0.7	2.9	0.4	0.4	0.7	1.7	-0.1	0.5	0.2	1.2
Commuting to job workplace: Cycle	0.6	0.8	1.5	0.0	0.4	1.0	-0.9	1.2	1.2	-0.3	1.0
Myopia	2.0	2.9	10.6	1.2	-0.2	-0.5	-0.4	1.8	-2.4	-1.4	-3.3
Vascular/heart problems diagnosed by doctor	0.2	0.7	2.1	-1.2	0.5	0.1	0.2	-0.9	0.9	1.4	0.2
Cholesterol lowering medication	0.7	1.1	2.2	-1.1	1.5	1.4	0.4	1.1	1.1	-0.1	0.5
Medication: Omeprazole (e.g. Zanprol)	0.7	0.9	2.1	0.2	-1.0	-0.9	1.4	-0.3	-1.0	1.5	0.4
Pain experienced in last month	0.6	1.0	3.1	-1.0	0.8	1.3	-1.8	0.2	0.2	-0.4	1.0
Supplements: Calcium	0.2	0.2	0.8	0.1	0.0	-0.9	0.3	0.9	-0.1	0.0	-0.6
Basal cell carcinoma (self-reported)	0.2	0.3	0.9	-0.3	-0.5	-0.2	-1.0	-0.2	-0.1	0.5	-0.7
Heart attack/myocardial infarction (self-reported)	0.1	0.1	0.3	-0.4	0.1	-0.3	0.5	0.4	0.2	0.4	0.4
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	2.4	1.0	-0.4	0.1	1.5	0.1	0.3	0.3	0.5
Heart disease (siblings)	0.3	0.3	1.9	0.4	-0.1	0.2	1.4	0.4	0.1	-0.2	0.6
Alcohol drinker status: Previous	0.5	0.6	2.0	-0.3	-0.6	-1.4	-0.5	-1.3	0.2	-0.5	-0.2
Pack years of smoking	1.2	1.8	4.0	2.0	-1.2	-1.2	-0.7	-0.7	-1.4	-1.2	-1.8
Impedance of whole body	0.6	3.1	10.6	-0.5	1.8	1.4	0.4	1.2	1.8	2.1	3.3
Leg fat mass (left)	0.5	1.8	5.0	-0.6	1.7	2.2	0.2	1.2	-0.4	0.5	-2.0
Arm predicted mass (left)	0.9	4.4	20.2	-1.8	-1.0	-0.6	1.4	-2.4	-1.4	-0.6	-4.5