Hub : Genes

TAS2R4

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Subcutaneous 0.0660 0.0240 8.6e-05 0.084 NA 0.057 NA 0.073 2.2e-07 NA 1.8e-05 NA 1.5e-06
2 GTEx Adipose Visceral Omentum 0.0880 0.0360 1.2e-03 0.073 NA 0.029 NA 0.068 1.2e-04 NA 1.2e-02 NA 2.1e-04
3 GTEx Artery Aorta 0.1300 0.0540 6.3e-04 0.046 NA 0.035 NA 0.046 1.5e-03 NA 4.9e-03 NA 1.5e-03
4 GTEx Artery Coronary 0.1530 0.0720 6.9e-03 0.099 NA 0.051 NA 0.014 3.2e-04 NA 8.3e-03 NA 1.1e-01
5 GTEx Artery Tibial 0.0643 0.0233 9.3e-05 0.084 NA 0.061 NA 0.080 3.7e-07 NA 1.6e-05 NA 7.4e-07
6 GTEx Brain Caudate basal ganglia 0.1410 0.0620 3.9e-03 0.071 NA 0.096 NA 0.096 4.4e-03 NA 1.1e-03 NA 1.1e-03
7 GTEx Brain Cerebellar Hemisphere 0.1800 0.0600 2.1e-04 0.274 NA 0.108 NA -0.011 9.7e-08 NA 1.0e-03 NA 8.3e-01
8 GTEx Brain Cerebellum 0.2780 0.0680 1.0e-07 0.390 NA 0.311 NA 0.358 1.4e-12 NA 6.8e-10 NA 1.9e-11
9 GTEx Brain Hypothalamus 0.2540 0.0860 2.3e-04 0.202 NA 0.056 NA 0.118 1.8e-05 NA 2.0e-02 NA 1.1e-03
10 GTEx Brain Nucleus accumbens basal ganglia 0.1710 0.0620 8.1e-04 0.151 NA 0.006 NA -0.004 7.8e-05 NA 2.2e-01 NA 4.1e-01
11 GTEx Breast Mammary Tissue 0.1060 0.0370 1.0e-04 0.160 NA 0.076 NA 0.122 1.3e-08 NA 9.3e-05 NA 8.1e-07
12 GTEx Breast Mammary Tissue (Male) 0.1472 0.0693 1.1e-02 0.112 NA 0.030 NA 0.045 1.5e-03 NA 6.8e-02 NA 3.3e-02
13 GTEx Cells Transformed fibroblasts 0.1180 0.0400 5.7e-06 0.118 NA 0.103 NA 0.106 3.8e-09 NA 3.7e-08 NA 2.3e-08
14 GTEx Colon Sigmoid 0.1970 0.0680 3.3e-04 0.079 NA 0.089 NA 0.011 9.9e-04 NA 4.8e-04 NA 1.3e-01
15 GTEx Colon Transverse 0.1410 0.0470 1.5e-05 0.138 NA 0.117 NA 0.096 4.3e-07 NA 3.3e-06 NA 2.6e-05
16 GTEx Esophagus Gastroesophageal Junction 0.2130 0.0810 3.2e-04 0.048 NA 0.033 NA 0.008 7.7e-03 NA 2.4e-02 NA 1.5e-01
17 GTEx Esophagus Mucosa 0.0880 0.0320 5.1e-05 0.096 NA 0.125 NA 0.007 6.1e-07 NA 1.0e-08 NA 9.6e-02
18 GTEx Esophagus Muscularis 0.1440 0.0410 3.4e-08 0.154 NA 0.160 NA 0.156 1.2e-09 NA 5.7e-10 NA 1.0e-09
19 GTEx Liver 0.2630 0.0830 2.3e-04 0.049 NA 0.066 NA 0.037 1.7e-02 NA 6.5e-03 NA 3.3e-02
20 GTEx Lung 0.1853 0.0423 1.8e-12 0.190 NA 0.197 NA 0.000 1.9e-14 NA 4.9e-15 NA 3.0e-01
21 GTEx Nerve Tibial 0.2329 0.0538 7.4e-12 0.214 NA 0.154 NA 0.201 3.6e-15 NA 4.7e-11 NA 3.0e-14
22 GTEx Ovary 0.3400 0.0860 7.9e-06 0.236 NA 0.259 NA 0.259 1.7e-06 NA 4.6e-07 NA 4.6e-07
23 GTEx Pancreas 0.2470 0.0700 6.0e-07 0.024 NA 0.104 NA 0.072 3.3e-02 NA 3.9e-05 NA 5.6e-04
24 GTEx Pituitary 0.3830 0.0940 4.2e-07 0.353 NA 0.299 NA -0.012 9.7e-10 NA 3.1e-08 NA 9.6e-01
25 GTEx Prostate 0.2390 0.0930 1.8e-03 0.193 NA 0.031 NA 0.127 1.4e-05 NA 5.7e-02 NA 4.4e-04
26 GTEx Skin Not Sun Exposed Suprapubic 0.1370 0.0480 2.6e-05 0.107 NA 0.132 NA 0.113 1.7e-06 NA 1.1e-07 NA 9.7e-07
27 GTEx Skin Sun Exposed Lower leg 0.1320 0.0370 7.7e-10 0.125 NA 0.097 NA 0.129 1.7e-10 NA 2.2e-08 NA 8.7e-11
28 GTEx Small Intestine Terminal Ileum 0.3260 0.1020 1.4e-04 0.125 NA 0.108 NA 0.137 1.0e-03 NA 2.2e-03 NA 5.8e-04
29 GTEx Spleen 0.3410 0.1020 2.7e-06 0.182 NA 0.179 NA 0.149 2.1e-05 NA 2.4e-05 NA 1.2e-04
30 GTEx Testis 0.1270 0.0450 8.6e-05 0.159 NA 0.138 NA 0.089 1.5e-07 NA 1.0e-06 NA 9.1e-05
31 GTEx Thyroid 0.1840 0.0450 7.0e-14 0.258 NA 0.228 NA 0.246 8.3e-20 NA 2.2e-17 NA 7.8e-19
32 GTEx Uterus 0.2930 0.0860 5.0e-05 0.337 NA 0.304 NA 0.352 1.0e-07 NA 5.6e-07 NA 4.6e-08
33 METSIM Adipose 0.0453 0.0164 3.1e-05 0.039 0.030 0.022 0.029 0.033 1.5e-06 2.0e-05 2.7e-04 2.9e-05 8.3e-06
34 NTR Blood 0.0328 0.0103 5.7e-09 0.037 0.028 0.029 0.030 0.034 5.7e-12 1.6e-09 1.0e-09 4.3e-10 2.4e-11
35 ROSMAP Brain Pre-frontal Cortex 0.1238 0.0322 3.3e-16 0.173 0.127 0.146 0.137 0.164 1.0e-21 4.7e-16 2.4e-18 3.3e-17 1.7e-20
36 TCGA Bladder Urothelial Carcinoma 0.0260 0.0210 3.3e-03 0.034 0.023 0.031 NA 0.028 7.1e-04 4.3e-03 1.1e-03 NA 1.8e-03
37 TCGA Breast Invasive Carcinoma 0.0311 0.0237 1.0e-07 0.038 0.034 0.019 NA 0.037 2.3e-08 1.4e-07 6.7e-05 NA 3.1e-08
38 TCGA Cervical Squamous Cell Carcinoma 0.0590 0.0460 1.9e-03 0.027 0.025 -0.001 NA 0.036 1.8e-02 2.1e-02 3.6e-01 NA 7.0e-03
39 TCGA Colon Adenocarcinoma 0.0830 0.0470 1.1e-07 0.119 0.126 0.125 NA 0.118 2.2e-07 1.0e-07 1.1e-07 NA 2.5e-07
40 TCGA Kidney Renal Clear Cell Carcinoma 0.1909 0.1258 4.5e-08 0.072 0.073 0.099 NA 0.077 1.8e-08 1.3e-08 3.5e-11 NA 5.0e-09
41 TCGA Brain Lower Grade Glioma 0.1081 0.0517 0.0e+00 0.192 0.201 0.196 NA 0.194 2.3e-21 2.3e-22 8.1e-22 NA 1.5e-21
42 TCGA Lung Adenocarcinoma 0.0384 0.0341 9.3e-04 0.024 0.013 0.029 NA 0.014 6.9e-04 9.9e-03 2.5e-04 NA 8.3e-03
43 TCGA Lung Squamous Cell Carcinoma 0.0515 0.0352 1.2e-06 0.050 0.043 0.033 NA 0.047 2.1e-06 1.1e-05 1.1e-04 NA 4.5e-06
44 TCGA Ovarian Serous Cystadenocarcinoma 0.0350 0.0270 2.1e-03 0.038 0.011 0.010 NA 0.003 1.3e-03 5.7e-02 6.8e-02 NA 1.9e-01
45 TCGA Pheochromocytoma and Paraganglioma 0.0880 0.0610 5.4e-04 0.081 0.009 0.052 NA -0.004 3.9e-04 1.3e-01 4.1e-03 NA 5.1e-01
46 TCGA Prostate Adenocarcinoma 0.0783 0.0651 2.5e-04 0.027 0.001 0.023 NA 0.001 7.2e-04 2.3e-01 1.7e-03 NA 2.3e-01
47 TCGA Rectum Adenocarcinoma 0.1100 0.0880 6.1e-03 0.065 0.017 0.065 NA 0.009 1.3e-02 1.3e-01 1.3e-02 NA 1.9e-01
48 TCGA Soft Tissue Sarcoma 0.0400 0.0310 2.7e-03 0.044 0.045 0.040 NA 0.044 1.2e-03 1.1e-03 1.9e-03 NA 1.2e-03
49 TCGA Testicular Germ Cell Tumors 0.0600 0.0490 9.1e-03 0.040 0.019 0.016 NA -0.008 1.5e-02 6.8e-02 8.7e-02 NA 9.3e-01
50 TCGA Thyroid Carcinoma 0.0440 0.0270 2.8e-06 0.063 0.057 0.046 NA 0.055 9.7e-07 3.3e-06 2.5e-05 NA 4.1e-06
51 TCGA Uterine Corpus Endometrial Carcinoma 0.1950 0.1450 9.2e-04 0.086 0.090 0.122 NA 0.066 2.2e-03 1.7e-03 2.8e-04 NA 6.5e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51
Bipolar Disorder (2018) 0.2 0.3 1.7 0.5 -0.0 0.4 0.4 0.3 -0.8 0.5 0.4 0.9 0.4 0.4 -1.3 0.5 -0.3 0.4 -0.1 -0.1 0.6 -1.0 0.3 0.4 0.3 0.3 0.3 0.6 1.0 0.4 0.3 0.7 0.6 0.5 0.8 0.5 -0.4 0.4 0.5 0.4 0.5 0.4 -0.6 0.1 -0.1 0.4 0.4 1.2 -0.2 -0.4 0.5 0.3 0.5 -0.2
Bipolar Disorder or Schizophrenia 0.2 0.6 2.9 0.8 0.5 0.7 1.7 0.8 -1.1 0.1 0.7 1.1 0.8 0.7 0.0 0.8 0.1 0.8 0.6 0.2 0.9 -0.5 0.6 0.9 0.6 -0.1 0.7 0.5 1.1 0.7 0.6 0.9 0.8 0.8 0.9 0.8 -0.8 0.8 0.7 0.8 0.8 0.8 -0.0 0.5 0.5 0.7 0.8 1.5 -0.3 -0.6 0.8 0.7 0.8 -0.3
Depressed Affect (Nagel 2018) 0.1 0.2 1.5 -0.3 -1.2 -0.3 -0.2 -0.4 -0.2 -0.8 -0.3 -0.5 -0.3 -0.3 0.2 -0.3 -0.6 -0.6 0.2 -1.0 -0.4 -1.1 -0.4 -0.3 0.0 -0.5 0.2 -0.4 0.1 -0.3 -0.7 -0.5 -0.5 -0.3 -0.3 -0.1 0.3 -0.3 -0.3 -0.3 -0.3 -0.2 -0.3 -0.3 -0.5 -0.3 -0.2 -0.0 -0.7 -0.3 -0.2 -0.3 -0.2 -0.7
Depression (Nagel 2018) 0.3 0.5 2.8 0.7 0.0 0.7 0.5 0.8 -0.9 0.2 0.5 0.7 0.9 0.7 -0.5 0.9 1.0 0.3 1.7 -0.3 0.6 0.5 0.7 0.9 1.0 0.2 1.2 -0.2 0.2 0.5 0.3 0.6 0.7 0.8 0.7 0.9 -0.8 0.7 0.7 0.7 0.6 0.8 0.1 0.7 0.4 0.7 0.8 0.6 0.1 0.2 0.8 0.8 0.8 0.3
Intelligence (Savage-Jansen 2018) 0.6 1.8 7.6 -1.1 -2.0 -1.7 -1.7 -1.3 0.6 -0.8 -1.2 -1.4 -1.2 -1.4 0.9 -1.4 -0.7 -1.2 -2.8 -2.0 -1.6 -1.8 -1.2 -1.1 -1.5 -0.2 -1.2 -2.5 -1.5 -1.2 -1.8 -1.5 -1.7 -1.2 -1.4 -1.3 1.4 -1.3 -1.1 -1.2 -1.1 -1.3 -0.1 -1.0 -0.8 -1.3 -1.2 -1.4 -0.3 -0.6 -1.4 -1.1 -1.3 -0.4
Neuroticism (Nagel 2018) 0.4 1.0 4.0 -0.8 -1.6 -0.8 -0.6 -0.9 0.4 -1.5 -1.1 -1.2 -0.9 -0.8 -0.5 -1.1 -0.9 -1.1 -0.5 -1.5 -1.1 -2.0 -1.1 -1.1 -0.9 -1.0 -0.6 -0.7 -0.1 -1.0 -1.2 -1.2 -1.3 -1.1 -1.1 -0.7 0.9 -1.1 -0.8 -0.8 -0.9 -0.9 -0.2 -1.0 -1.4 -1.1 -0.9 -0.5 -1.2 -1.1 -0.8 -0.9 -0.9 -1.1
Schizophrenia (2018) 0.2 0.4 3.6 0.7 0.6 0.5 1.9 0.7 -0.7 -0.2 0.6 0.6 0.6 0.6 1.0 0.6 0.4 0.8 0.9 0.6 0.7 0.2 0.6 0.8 0.6 -0.3 0.7 0.2 0.6 0.6 0.5 0.6 0.5 0.6 0.6 0.7 -0.6 0.6 0.6 0.6 0.6 0.6 0.3 0.6 0.6 0.6 0.6 0.9 0.1 -0.2 0.6 0.7 0.6 0.2
Schizophrenia vs Biploar Disorder 0.2 0.2 4.2 0.0 0.6 0.4 0.7 0.2 0.1 -0.7 0.1 -0.1 0.1 0.2 2.0 0.1 0.9 0.3 1.0 -0.2 -0.1 1.1 0.0 0.2 0.1 -0.8 0.4 0.4 0.4 0.1 0.3 -0.0 0.3 0.2 -0.0 0.0 -0.0 0.1 0.1 0.1 0.0 0.1 0.3 0.2 0.8 0.1 0.1 -0.1 0.1 -0.6 0.0 0.2 0.0 0.3
Worry (Nagel 2018) 0.2 0.5 1.9 -0.6 -1.1 -0.8 -0.3 -0.7 0.3 -0.7 -0.7 -0.8 -0.7 -0.6 -0.2 -0.6 -0.2 -0.5 0.0 -1.0 -0.6 -1.4 -1.0 -0.7 -0.8 -0.3 -0.7 -0.0 -0.0 -0.6 -0.6 -0.7 -0.9 -0.6 -0.6 -0.8 0.7 -0.6 -0.6 -0.6 -0.7 -0.6 -1.2 -0.8 -0.9 -0.7 -0.7 -0.2 -0.8 -0.4 -0.6 -0.8 -0.6 -0.8
Alzheimer’s Disease (in mother) 0.6 0.7 5.1 -0.6 0.2 -1.5 -1.3 -0.5 0.4 -0.9 -0.6 -0.9 -0.7 -0.5 -2.3 -0.7 -1.3 -0.5 -1.9 0.3 -0.7 -0.4 -0.6 -0.6 -1.4 -0.7 -1.2 -0.0 -1.1 -0.5 -0.2 -0.7 -0.6 -0.6 -0.8 -0.5 0.5 -0.6 -0.7 -0.6 -0.6 -0.6 -0.5 -0.8 -0.5 -0.6 -0.6 0.1 -1.3 -1.5 -0.6 -0.6 -0.6 -1.2
Alzheimer’s Disease (in father) 1.3 1.5 4.8 -1.3 -1.4 -0.4 -1.1 -1.2 1.1 -1.3 -1.1 -1.5 -1.3 -1.0 -0.0 -1.0 -0.3 -1.0 1.1 -1.6 -1.4 -1.8 -1.2 -1.4 -1.3 -2.2 -1.4 -0.9 -0.0 -1.2 -1.2 -1.4 -1.5 -1.3 -1.3 -1.1 1.3 -1.1 -1.2 -1.2 -1.3 -1.2 -1.2 -1.3 -1.3 -1.1 -1.2 -0.8 -1.0 -0.9 -1.1 -1.3 -1.2 -0.9
Alzheimer’s Disease (including proxy) 2.7 3.9 6.8 -2.1 -1.4 -1.8 -1.9 -2.0 1.9 -2.2 -1.9 -2.2 -2.2 -1.9 -2.0 -2.1 -2.0 -1.8 -1.3 -1.3 -2.0 -1.9 -2.0 -2.2 -2.4 -2.4 -2.6 -1.4 -1.3 -1.9 -1.8 -2.1 -1.9 -2.1 -2.1 -1.9 2.0 -2.0 -2.2 -2.0 -2.1 -2.0 -1.4 -2.1 -1.8 -1.9 -2.0 -1.2 -2.3 -2.2 -2.0 -2.1 -2.0 -2.1
Crohns Disease (2017) 0.2 0.5 3.7 -0.5 -0.2 -0.2 -0.9 -0.3 0.8 -1.0 -0.3 -1.4 -0.6 -0.5 0.3 -0.5 0.2 -0.0 -1.5 -0.2 -1.0 0.4 -1.1 -0.7 -0.6 -0.8 -0.3 -1.9 0.1 -0.3 -0.6 -1.2 -0.8 -0.6 -1.1 -0.4 0.7 -0.6 -0.5 -0.4 -0.4 -0.5 0.8 -0.2 0.5 -0.4 -0.4 -0.6 -0.1 -1.1 -0.6 -0.2 -0.6 0.0
Irritable Bowel Disease (IBD) 1.1 2.7 6.5 -1.6 -1.8 -1.2 -2.0 -1.7 1.9 -1.9 -1.6 -2.0 -1.7 -1.6 -0.2 -1.6 -0.8 -1.3 -1.3 -1.3 -2.0 -1.2 -2.1 -1.9 -1.6 -1.3 -1.3 -2.5 -0.5 -1.6 -2.0 -2.1 -1.7 -1.7 -1.8 -1.5 1.8 -1.6 -1.4 -1.6 -1.7 -1.6 -1.2 -1.5 -1.1 -1.6 -1.6 -2.0 -1.6 -2.1 -1.6 -1.5 -1.6 -1.4
Ulcerative Colitis (UC) 1.7 3.2 6.3 -1.8 -2.2 -1.4 -2.0 -2.1 1.9 -1.7 -1.9 -1.6 -1.8 -1.8 -0.5 -1.8 -1.4 -1.6 -1.0 -1.4 -1.9 -2.1 -2.1 -1.9 -1.8 -1.1 -1.4 -1.9 -0.5 -1.9 -2.3 -1.9 -1.7 -1.8 -1.6 -1.9 2.0 -1.7 -1.6 -1.9 -1.9 -1.8 -2.5 -1.9 -1.8 -1.9 -1.8 -1.8 -2.0 -1.9 -1.7 -1.9 -1.8 -1.9
Major Depression (MDD) 1.0 1.2 5.2 1.0 0.8 0.5 2.3 1.2 -1.1 1.3 1.1 1.2 1.1 1.1 0.9 1.2 0.5 1.2 1.0 0.9 1.0 0.6 1.4 0.9 1.1 0.8 1.2 1.6 0.2 1.1 1.5 1.3 0.7 1.1 1.1 1.1 -1.1 1.2 1.2 1.1 1.0 1.1 0.0 1.0 0.5 1.1 1.1 1.0 0.9 1.0 1.2 1.0 1.1 1.1
Reaction Time 0.7 1.3 3.5 -1.1 -0.6 -1.4 -1.2 -1.1 1.2 -1.3 -1.3 -1.4 -1.2 -1.3 -1.1 -1.2 -0.2 -1.9 -0.8 -0.7 -1.3 0.6 -1.7 -1.1 -1.3 -0.6 -1.4 -1.0 -0.8 -1.2 -0.7 -1.2 -0.8 -1.1 -1.4 -1.2 1.2 -1.3 -1.3 -1.2 -1.1 -1.2 -0.5 -1.1 -0.3 -1.3 -1.2 -1.3 -1.1 -1.0 -1.4 -1.2 -1.3 -1.3
Verbal and Numeric Reasoning (VNR) 1.6 3.8 10.7 -1.9 -2.8 -2.3 -1.6 -2.2 1.4 -1.7 -2.0 -1.6 -1.9 -2.0 1.3 -2.2 -1.7 -2.1 -1.6 -3.0 -2.0 -2.3 -1.7 -1.8 -1.7 -1.5 -2.0 -3.3 -2.4 -1.9 -2.6 -2.0 -1.6 -1.9 -1.7 -2.1 2.1 -2.0 -1.9 -1.9 -1.9 -2.0 -0.9 -1.8 -1.3 -2.0 -2.0 -2.3 -1.0 -1.1 -2.0 -1.9 -2.0 -1.1
Breast Cancer 0.1 0.1 0.9 -0.1 0.0 -0.0 -0.3 -0.2 -0.2 -0.1 -0.3 -0.6 -0.2 -0.3 0.4 -0.3 -0.3 -0.3 -0.9 -0.1 -0.3 -0.9 -0.5 -0.2 -0.6 0.5 -0.1 -0.6 0.5 -0.2 -0.2 -0.4 -0.1 -0.1 -0.5 -0.3 0.1 -0.3 -0.1 -0.2 -0.1 -0.3 -0.2 -0.3 -0.2 -0.3 -0.3 -0.0 -0.3 -0.7 -0.2 -0.2 -0.2 -0.2
Ovarian Cancer 0.1 0.2 0.7 -0.4 0.4 -0.4 -0.2 -0.1 0.3 -0.1 -0.3 -0.7 -0.4 -0.3 -0.7 -0.3 -0.5 -0.7 0.5 0.2 -0.3 -0.1 -0.3 -0.5 -0.2 0.5 -0.5 -0.2 -0.8 -0.4 -0.0 -0.4 -0.3 -0.5 -0.5 -0.4 0.3 -0.3 -0.6 -0.4 -0.4 -0.3 0.1 -0.2 0.0 -0.3 -0.2 -0.4 -0.7 -0.3 -0.4 -0.2 -0.3 -0.8
Prostate Cancer 1.9 2.7 5.0 1.9 1.9 1.6 1.6 1.8 -2.0 1.5 1.6 1.1 1.9 1.6 0.4 1.6 1.1 1.9 0.7 1.6 1.6 1.1 1.8 2.0 1.2 1.5 2.2 1.2 2.0 1.7 1.8 1.4 1.1 1.9 1.2 1.5 -2.0 1.7 2.0 1.7 1.9 1.6 1.2 1.7 1.1 1.6 1.6 1.6 2.2 1.5 1.7 1.6 1.7 2.1
Age at First Birth 1.3 1.9 3.7 -1.3 -1.9 -1.4 -1.9 -1.5 1.6 -1.4 -1.2 -1.7 -1.4 -1.5 -1.1 -1.4 -0.8 -1.5 -1.2 -1.1 -1.6 -1.2 -1.4 -1.4 -1.4 -0.3 -1.5 -1.2 -1.1 -1.3 -1.4 -1.6 -1.4 -1.4 -1.6 -1.5 1.6 -1.4 -1.4 -1.3 -1.5 -1.3 -1.1 -1.3 -0.6 -1.4 -1.3 -1.3 -1.6 -1.6 -1.5 -1.3 -1.4 -1.6
Bipolar Disorder (2011) 0.7 0.7 2.3 1.0 1.3 0.2 0.6 1.0 -0.9 0.7 0.9 0.6 0.8 0.7 -0.9 0.9 -0.3 1.1 -0.4 1.1 0.9 0.5 0.7 0.7 0.0 1.5 0.6 1.0 0.8 0.8 1.2 0.8 0.4 0.7 0.6 0.8 -1.0 0.8 0.8 0.9 0.8 0.9 -0.4 0.6 -0.1 0.8 0.8 1.5 0.1 0.4 1.0 0.7 0.9 0.1
Body Mass Index (BMI) (2010) 0.6 0.8 1.9 -1.1 -0.3 -1.3 -0.4 -0.8 0.9 -1.1 -0.9 -1.0 -1.0 -1.0 -0.9 -1.0 -0.9 -0.7 -0.6 0.2 -0.9 -0.3 -0.6 -1.1 -1.2 -1.0 -1.1 -0.2 -1.4 -0.9 -0.4 -0.8 -0.9 -1.0 -1.0 -0.8 1.0 -1.0 -0.9 -1.0 -1.0 -1.0 -0.9 -1.1 -1.0 -1.0 -1.0 -0.8 -0.9 -1.0 -0.9 -1.0 -1.0 -0.8
Coronary Artery Disease (CAD) 3.7 4.4 9.4 2.4 2.4 1.6 2.5 2.0 -1.6 2.2 1.5 3.1 1.9 2.2 -0.8 2.3 1.9 2.1 2.0 1.7 2.7 2.1 2.3 1.6 2.7 1.5 1.9 2.2 1.2 1.6 2.1 2.6 2.6 1.5 2.8 2.4 -1.9 2.3 2.3 2.2 2.0 2.1 0.8 2.1 2.0 1.7 2.0 1.4 2.2 2.3 2.1 2.0 2.1 2.2
Crohns Disease (2012) 0.5 0.8 5.1 -0.8 -0.6 -0.4 -0.7 -0.5 1.3 -0.6 -0.7 -1.3 -0.8 -0.9 0.6 -0.8 0.3 -0.3 -1.0 -0.9 -1.2 1.0 -1.3 -0.9 -0.6 -1.0 -0.6 -2.3 -0.2 -0.7 -0.6 -1.2 -1.2 -0.9 -1.2 -0.8 1.0 -0.9 -0.9 -0.7 -0.7 -0.8 1.3 -0.4 -0.0 -0.7 -0.8 -1.5 0.4 0.1 -1.0 -0.5 -1.0 0.3
Mean Putamen Volume 1.8 2.0 4.0 1.5 1.3 0.9 1.4 1.5 -1.6 1.2 1.5 1.4 1.4 1.5 0.7 1.5 2.0 1.1 1.5 1.5 1.3 1.1 1.4 1.4 1.7 1.1 1.4 0.0 0.9 1.6 1.6 1.5 1.3 1.4 1.4 1.6 -1.4 1.5 1.4 1.5 1.4 1.5 1.8 1.6 1.9 1.6 1.5 0.9 1.5 1.4 1.4 1.6 1.4 1.4
Fasting Glucose 0.5 0.6 7.0 -0.7 -1.6 -0.1 0.1 -0.6 0.5 -0.9 -0.5 -0.5 -0.5 -0.6 -0.1 -0.9 0.1 -1.3 -0.8 -0.8 -0.9 -0.2 -0.7 -0.6 -0.6 -1.0 -0.6 -2.6 -0.2 -0.5 -1.0 -0.6 -0.5 -0.5 -0.6 -0.6 0.8 -0.7 -0.6 -0.7 -0.6 -0.6 -0.4 -0.3 0.7 -0.5 -0.6 -1.3 0.2 -0.0 -0.7 -0.4 -0.7 0.2
HbA1C 0.4 0.5 2.1 0.5 0.6 0.2 0.7 0.5 -1.0 0.3 1.3 0.1 0.6 0.3 1.2 0.5 0.5 0.7 0.9 0.0 0.4 1.4 0.7 1.4 0.1 0.1 0.6 0.3 -0.0 1.0 0.3 0.3 0.0 1.3 0.0 0.3 -1.1 0.5 0.2 0.4 0.3 0.6 -0.0 0.5 0.6 1.0 0.6 1.3 -0.6 0.1 0.5 0.5 0.6 -0.6
HDL Cholesterol 0.2 0.3 1.7 -0.6 -0.6 -0.4 -0.3 -0.5 0.4 -0.6 -0.5 -0.4 -0.5 -0.5 0.6 -0.5 0.2 -0.4 -0.3 -0.7 -0.4 -1.3 -0.6 -0.5 0.0 0.2 -0.8 -0.7 -0.4 -0.6 -0.2 -0.4 -0.5 -0.5 -0.4 -0.6 0.5 -0.5 -0.5 -0.6 -0.7 -0.5 -0.5 -0.5 -0.1 -0.5 -0.5 -0.9 -0.5 -0.5 -0.6 -0.5 -0.6 -0.5
LDL Cholesterol 0.3 0.4 4.3 -0.0 -0.3 -0.5 -1.5 -0.6 0.4 -0.3 -0.3 -0.6 -0.4 -0.6 -2.1 -0.4 -0.2 -0.5 -1.6 0.1 -0.6 -0.1 -0.2 -0.4 -1.2 -0.1 -0.7 -1.2 -0.5 -0.2 -0.5 -0.7 -0.5 -0.4 -0.6 -0.1 0.3 -0.5 -0.5 -0.0 0.1 -0.4 1.7 -0.2 0.3 -0.4 -0.3 0.4 -0.3 -0.4 -0.5 -0.2 -0.4 -0.5
Lupus 0.2 0.3 1.6 0.4 -0.3 0.7 -0.2 0.2 0.1 0.9 0.4 0.9 0.3 0.5 0.0 0.4 -0.3 0.5 0.2 0.6 0.6 0.1 0.5 0.4 0.6 0.8 0.5 0.3 1.3 0.4 0.5 0.9 0.5 0.4 0.8 0.4 -0.3 0.6 0.3 0.4 0.5 0.5 -0.1 0.3 0.9 0.4 0.5 0.5 -0.2 0.9 0.4 0.2 0.5 -0.6
Neuroticism (2016) 0.5 0.7 2.0 -0.9 -0.8 -0.4 -0.8 -1.0 0.5 -0.6 -0.7 -0.8 -0.9 -0.8 -1.0 -0.6 -0.7 -0.7 -0.1 -0.6 -1.0 -1.4 -0.7 -0.9 -1.2 -1.1 -0.9 -0.2 0.5 -0.8 -0.9 -1.0 -1.0 -0.8 -0.8 -0.9 0.9 -0.7 -0.8 -0.8 -0.9 -0.8 -1.4 -1.0 -1.0 -0.7 -0.9 -0.1 -1.0 -1.2 -0.7 -0.9 -0.8 -0.8
Primary Biliary Cirrhosis 1.5 2.1 4.7 1.5 1.7 1.0 1.6 1.4 -1.6 1.5 1.5 1.7 1.4 1.5 1.6 1.5 0.0 1.6 0.6 1.9 1.6 0.9 1.1 1.6 1.6 1.8 1.5 2.2 1.1 1.5 1.6 1.6 1.3 1.4 1.6 1.5 -1.6 1.5 1.4 1.5 1.5 1.5 0.8 1.3 1.0 1.5 1.5 1.8 0.6 0.8 1.5 1.4 1.6 0.5
Rheumatoid Arthritis 1.3 1.8 2.6 1.4 0.6 1.1 0.4 1.3 -1.3 1.2 1.5 1.6 1.5 1.5 0.3 1.5 1.1 1.4 1.1 0.3 1.5 1.0 1.5 1.6 1.4 0.7 1.3 0.2 1.3 1.5 1.0 1.4 1.5 1.5 1.6 1.4 -1.6 1.5 1.5 1.4 1.4 1.5 1.0 1.5 1.5 1.5 1.5 1.1 1.4 1.4 1.5 1.5 1.5 1.3
Schizophrenia (2014) 0.4 0.9 3.3 1.0 1.3 0.9 1.8 1.0 -0.9 0.2 0.9 1.0 1.0 0.9 0.6 0.8 0.4 1.3 0.7 1.0 1.1 0.5 0.9 1.2 0.8 0.5 1.2 0.9 1.3 0.9 1.0 1.0 0.9 0.9 0.9 0.8 -1.0 0.9 0.9 0.9 1.0 1.0 0.5 0.8 0.5 0.9 1.0 1.5 0.2 -0.2 1.0 0.9 1.0 0.2
Triglycerides 0.1 0.1 1.1 -0.3 -0.2 0.0 1.0 -0.1 -0.1 0.8 0.0 0.4 -0.0 0.0 -1.1 0.2 0.2 0.1 0.5 -0.1 0.1 0.7 0.2 -0.2 0.2 -0.6 0.1 0.1 -0.4 -0.1 0.0 0.2 0.4 -0.0 0.3 -0.3 0.2 0.0 0.1 -0.3 -0.2 -0.1 -0.7 -0.1 -0.4 -0.1 -0.1 -0.6 0.3 0.2 -0.0 -0.1 -0.1 0.5
Type 2 Diabetes (T2D) (2012) 0.2 0.2 3.9 -0.3 -0.1 -0.4 -1.6 0.2 -0.1 -0.3 0.0 -0.6 0.1 0.2 -1.4 0.0 0.3 -0.0 1.0 -0.2 -0.4 0.0 -0.1 0.0 -0.8 -0.3 -0.1 -0.5 0.0 0.1 0.2 -0.4 0.0 -0.0 -0.5 0.3 0.2 0.0 0.1 0.1 0.3 0.0 2.0 0.0 -0.1 0.1 0.1 -0.3 0.3 0.1 0.0 0.0 0.0 0.0
Ulcerative Colitis 1.1 1.5 2.7 -1.4 -1.7 -1.2 -0.8 -1.4 1.2 -0.8 -1.4 -0.9 -1.3 -1.3 0.0 -1.3 -0.7 -1.3 -0.1 -1.3 -1.2 -1.4 -1.4 -1.4 -0.8 -0.4 -0.8 -1.3 -0.7 -1.4 -1.6 -1.2 -1.1 -1.3 -1.0 -1.2 1.4 -1.2 -1.2 -1.4 -1.4 -1.3 -1.5 -1.3 -1.2 -1.3 -1.3 -1.6 -1.6 -1.3 -1.3 -1.3 -1.2 -1.5
Blood Eosinophil Count 0.2 1.9 4.6 1.3 1.1 1.3 2.1 1.4 -1.4 1.6 1.4 1.5 1.4 1.5 1.1 1.6 1.7 1.7 1.9 0.7 1.4 0.9 1.6 1.1 1.5 0.5 1.5 1.7 1.4 1.4 1.1 1.4 1.1 1.3 1.5 1.5 -1.4 1.4 1.3 1.4 1.4 1.5 0.8 1.2 0.4 1.4 1.4 1.8 0.6 0.8 1.5 1.3 1.5 0.7
Blood Platelet Count 0.0 0.3 3.9 0.2 0.5 0.6 -0.4 0.3 -0.3 0.4 0.3 0.5 0.3 0.3 2.0 0.4 1.8 0.3 0.4 0.3 0.6 -0.1 0.8 -0.0 0.6 0.3 0.3 0.6 0.7 0.2 0.3 0.4 0.4 0.2 0.5 0.2 -0.5 0.3 0.3 0.3 0.2 0.3 -0.4 0.2 -0.2 0.3 0.3 0.5 0.1 0.0 0.4 0.3 0.3 0.3
Blood Red Count 0.1 1.3 5.2 1.1 0.8 0.6 2.3 0.8 -1.3 1.6 1.1 1.2 1.1 1.3 0.5 1.4 1.7 1.5 1.2 0.3 1.1 0.4 0.9 1.2 1.6 0.4 0.6 0.2 0.9 1.1 0.7 1.1 1.2 1.1 1.2 0.9 -1.0 1.3 1.1 1.1 1.1 1.2 0.9 1.1 1.7 1.1 1.2 0.8 0.8 1.2 1.0 1.1 1.1 0.6
Blood White Count 0.3 2.3 4.4 1.6 1.3 0.7 2.1 1.6 -2.0 2.0 1.5 1.8 1.6 1.5 1.4 1.8 1.2 1.6 1.7 1.5 1.6 1.1 1.6 1.5 2.1 0.9 1.5 2.0 0.6 1.5 1.4 1.6 1.4 1.4 1.7 1.6 -1.7 1.6 1.5 1.6 1.6 1.6 0.5 1.4 0.3 1.5 1.6 2.1 0.5 0.9 1.7 1.5 1.7 0.6
Heel T-Score 0.0 0.3 1.8 0.2 0.8 0.7 1.4 0.4 -0.5 0.2 0.3 0.6 0.4 0.5 -1.0 0.4 0.9 -0.1 1.3 0.5 0.7 0.3 0.6 0.2 0.4 -0.2 0.3 0.6 0.4 0.3 0.7 0.7 0.8 0.3 0.6 0.5 -0.4 0.3 -0.0 0.3 0.3 0.4 1.0 0.4 0.8 0.3 0.5 0.4 -0.8 -0.3 0.2 0.4 0.4 -0.9
BMI 0.1 0.7 6.8 0.6 0.8 0.5 1.3 0.5 -0.7 0.7 0.5 0.2 0.6 0.6 1.4 0.7 0.4 0.6 -0.8 1.0 0.4 -1.7 0.8 0.5 0.8 0.7 1.1 1.9 0.9 0.5 0.6 0.3 -0.7 0.4 0.3 0.6 -0.5 0.8 0.7 0.6 0.6 0.6 -0.2 0.6 0.1 0.5 0.6 -0.1 1.3 2.6 0.6 0.4 0.6 0.9
Height 0.0 0.1 1.4 0.1 -0.4 0.4 0.1 0.0 -0.4 0.3 -0.1 -0.4 0.1 -0.0 0.7 0.1 0.5 0.4 0.1 0.2 -0.3 -1.2 -0.1 -0.1 -0.1 -0.1 0.3 0.2 0.0 -0.0 0.1 -0.2 -0.6 0.0 -0.3 -0.1 -0.0 0.0 0.3 -0.0 0.1 -0.1 -0.2 0.0 -0.5 0.0 -0.1 0.0 0.9 0.2 0.1 -0.0 -0.0 1.0
Waist Hip Ratio (WHR) 0.0 0.2 1.7 0.3 -0.1 0.5 0.2 0.3 0.0 0.3 0.4 0.3 0.2 0.5 0.3 0.5 1.1 0.2 1.3 0.3 0.1 0.0 0.4 0.2 0.4 -0.5 0.2 0.4 0.4 0.3 0.3 0.2 0.2 0.3 0.3 0.4 -0.2 0.4 0.4 0.3 0.2 0.3 -0.1 0.3 -0.1 0.4 0.3 0.4 0.4 0.2 0.4 0.3 0.3 0.7
Systolic Blood Pressure 0.0 0.2 2.2 0.3 0.2 0.3 1.0 0.3 -0.9 0.5 0.1 0.9 0.4 0.1 -0.7 0.2 0.9 -0.0 0.1 -0.8 0.5 0.4 0.6 0.4 0.2 0.7 0.6 0.2 0.4 0.1 0.3 0.7 0.3 0.3 0.7 0.1 -0.3 0.2 0.4 0.1 0.3 0.2 -0.1 0.3 0.0 0.1 0.2 -0.4 0.9 1.5 0.1 0.1 0.2 0.5
Smoking Status 0.1 0.1 0.9 -0.2 -0.7 -0.4 -0.3 -0.0 -0.1 -0.3 -0.2 0.0 -0.1 -0.2 -0.8 -0.1 0.6 -0.4 0.6 0.5 -0.3 -0.1 -0.2 -0.3 -0.1 -1.0 0.1 -0.5 -0.8 -0.2 -0.2 -0.0 0.2 -0.2 -0.1 -0.1 0.3 -0.3 -0.1 -0.2 -0.2 -0.3 0.2 -0.1 -0.3 -0.2 -0.2 -0.2 0.1 -0.4 -0.2 -0.1 -0.3 0.3
Allergy or Eczema 0.5 1.2 4.3 -1.1 -1.1 -0.8 -1.8 -1.0 0.6 -1.5 -1.0 -1.5 -1.1 -1.1 0.7 -1.1 -0.3 -1.1 -0.8 -2.1 -1.4 -1.1 -0.9 -1.0 -1.2 -0.6 -1.1 -1.6 -0.7 -1.0 -1.3 -1.3 -1.7 -1.1 -1.4 -0.9 1.2 -1.0 -1.0 -1.0 -1.1 -1.1 -0.8 -0.9 -1.0 -1.0 -1.1 -1.3 -0.2 0.0 -1.1 -1.1 -1.1 -0.2
Cardiovascular Disease 0.2 0.8 3.4 0.9 0.3 0.9 1.0 0.7 -0.9 0.6 0.9 1.0 0.9 0.9 1.9 1.0 1.6 0.7 0.8 -0.2 0.8 0.6 1.0 0.7 0.9 1.1 0.9 0.6 0.4 0.8 0.3 0.8 0.9 0.8 1.0 0.9 -0.8 0.9 0.9 0.9 0.8 0.9 0.8 1.0 0.8 0.9 0.9 0.6 1.0 1.0 0.8 0.9 0.9 1.0
Hypothyroidism (self reported) 1.1 2.6 6.4 -1.7 -1.9 -1.9 -1.3 -1.6 1.8 -1.5 -1.7 -1.9 -1.7 -1.6 -0.2 -1.8 -1.4 -1.5 -2.4 -1.7 -1.8 -1.8 -1.4 -1.6 -1.9 -0.9 -1.1 -1.2 -1.1 -1.7 -1.5 -1.7 -2.5 -1.7 -1.9 -1.8 1.7 -1.6 -1.6 -1.7 -1.6 -1.7 -0.9 -1.5 -1.1 -1.7 -1.7 -2.5 -0.4 0.3 -1.8 -1.7 -1.7 -0.8
Respiratory disease 1.8 4.0 6.2 -2.0 -2.3 -1.2 -2.1 -2.2 1.8 -2.3 -2.1 -2.2 -2.0 -2.1 -1.7 -2.1 -1.6 -1.8 -2.0 -2.5 -2.2 -2.5 -1.8 -2.1 -2.3 -2.3 -1.6 -1.6 -0.7 -2.1 -2.5 -2.3 -2.1 -2.0 -2.2 -1.9 2.0 -2.0 -1.9 -2.1 -2.0 -2.1 -2.2 -2.0 -1.8 -2.1 -2.1 -2.3 -1.2 -0.8 -2.0 -2.1 -2.0 -1.3
Type 2 Diabetes (T2D) (2018) 0.1 0.2 2.7 -0.0 -0.2 0.2 -1.0 -0.0 -0.5 -0.0 -0.0 -0.6 -0.0 -0.1 0.2 -0.1 1.0 -0.3 0.1 -1.0 -0.2 0.2 0.1 -0.1 0.1 -0.2 -0.0 -1.6 0.2 -0.0 -0.4 -0.4 -0.5 -0.0 -0.5 -0.1 0.1 -0.2 -0.1 -0.0 -0.1 -0.1 0.8 0.1 0.6 -0.0 -0.0 -0.4 0.0 -0.3 -0.2 0.1 -0.1 0.0
Lung FEV1/FVC ratio 0.1 0.4 1.5 -0.5 -0.1 -1.0 -1.0 -0.5 0.5 -0.2 -0.5 -1.1 -0.5 -0.4 1.1 -0.6 -0.4 -0.3 -0.9 -0.7 -0.8 -0.1 -1.1 -0.5 -0.5 0.1 -0.8 -1.1 -0.7 -0.5 -0.6 -1.0 -0.7 -0.4 -0.9 -0.6 0.4 -0.7 -0.4 -0.5 -0.5 -0.6 0.1 -0.4 -0.4 -0.5 -0.6 -0.4 -0.1 -1.2 -0.5 -0.4 -0.6 0.2
Lung FVC 0.7 3.4 5.3 -2.1 -1.5 -1.9 -1.4 -1.8 2.3 -1.6 -1.9 -1.8 -2.0 -1.9 -1.5 -1.8 -2.2 -1.9 -0.7 -1.6 -1.7 -1.2 -2.2 -2.0 -2.0 -1.3 -2.0 -1.9 -1.8 -1.9 -1.8 -1.7 -1.6 -2.0 -1.8 -2.2 1.9 -1.9 -2.0 -2.0 -2.1 -1.9 -2.1 -2.0 -2.1 -1.9 -2.0 -1.8 -1.7 -1.2 -1.9 -2.0 -1.9 -1.6
Neuroticism 0.7 1.6 2.9 -1.1 -1.7 -1.3 -1.1 -1.3 1.0 -1.3 -1.2 -1.6 -1.2 -1.1 0.4 -1.2 -1.3 -1.2 -1.1 -1.6 -1.4 -1.4 -1.7 -1.2 -1.3 -0.8 -1.0 -1.6 -0.6 -1.2 -1.4 -1.6 -1.5 -1.1 -1.5 -1.2 1.1 -1.2 -1.2 -1.2 -1.2 -1.2 -1.2 -1.3 -1.2 -1.2 -1.2 -0.8 -1.5 -1.4 -1.1 -1.2 -1.1 -1.4
Chronotype (morning person) 0.1 0.3 4.5 0.3 -0.1 0.5 0.2 0.2 -0.1 0.1 0.4 -0.4 0.3 0.4 1.1 0.2 0.5 0.8 -2.1 -0.8 -0.1 -0.0 0.5 0.4 0.0 -0.2 0.2 -0.8 0.6 0.4 -0.4 -0.4 -0.0 0.3 -0.2 0.3 -0.3 0.2 0.2 0.4 0.3 0.4 1.2 0.5 0.5 0.4 0.4 0.3 0.4 -0.0 0.3 0.5 0.3 0.4
Hair Pigment 0.0 0.6 2.9 -0.9 0.2 -0.3 -0.5 -0.5 0.9 -1.7 -0.8 -0.9 -0.8 -1.0 -1.1 -0.8 0.3 -0.9 -0.3 0.5 -0.7 -0.4 -0.8 -0.9 -0.7 -0.9 -0.6 -1.4 -1.1 -0.8 -0.3 -0.5 -0.3 -0.9 -1.0 -0.6 0.7 -0.9 -0.7 -0.9 -0.8 -0.9 0.0 -0.6 -1.3 -0.8 -0.9 -1.2 0.2 -0.1 -0.8 -0.7 -0.9 0.4
Tanning 0.6 7.0 12.0 2.9 2.3 2.4 1.6 2.7 -2.5 3.5 2.8 3.1 2.9 2.8 -1.4 3.0 0.7 2.7 2.7 2.8 3.1 2.0 2.7 2.6 3.1 3.0 3.0 2.8 1.8 2.7 2.6 3.0 2.7 2.8 3.0 2.7 -2.8 2.8 2.7 2.8 2.8 2.9 2.2 2.8 2.4 2.8 2.9 2.6 1.9 2.3 2.8 2.8 2.9 1.7
Hand grip strength (left) 0.1 0.1 2.7 -0.1 -0.2 -0.4 1.6 -0.2 0.2 -0.2 -0.1 -0.0 -0.1 0.0 -0.4 -0.1 0.2 -0.2 0.8 0.2 0.1 -0.7 0.1 -0.2 0.1 -0.3 -0.1 0.5 -1.0 -0.1 0.1 0.1 -0.2 -0.2 -0.0 -0.3 0.1 -0.1 -0.2 -0.1 -0.1 -0.1 -0.1 -0.2 0.1 -0.1 -0.1 -0.1 -0.2 0.5 -0.2 -0.3 -0.1 -0.5
Number of treatments/medications taken 0.3 0.5 2.5 -0.5 -1.1 0.1 -0.7 -0.6 0.3 -1.2 -0.6 -1.2 -0.5 -0.8 0.4 -0.7 -0.0 -0.7 -1.6 -1.0 -0.9 -1.1 -0.5 -0.5 -0.9 -0.1 -0.1 -0.9 0.6 -0.6 -1.1 -1.2 -1.1 -0.6 -1.1 -0.4 0.5 -0.7 -0.5 -0.6 -0.5 -0.6 -0.3 -0.5 -0.6 -0.7 -0.6 -0.7 -0.2 -0.3 -0.6 -0.6 -0.6 -0.3
Average weekly spirits intake 1.9 2.4 5.2 -1.4 -1.0 -1.4 -0.7 -1.4 1.7 -1.4 -1.6 -2.1 -1.5 -1.8 -1.1 -1.6 -2.3 -1.6 -1.9 -1.0 -1.8 -0.6 -1.9 -1.4 -1.9 -1.7 -1.1 -0.7 -1.2 -1.5 -1.2 -1.8 -1.8 -1.5 -2.0 -1.7 1.5 -1.6 -1.5 -1.5 -1.4 -1.6 -1.5 -1.7 -1.3 -1.6 -1.6 -1.0 -1.5 -1.7 -1.6 -1.6 -1.6 -1.5
Sensitivity / hurt feelings 0.1 0.1 0.8 -0.1 0.1 -0.6 -0.9 -0.2 -0.1 -0.4 -0.1 -0.8 -0.1 -0.1 0.6 -0.1 0.1 0.2 0.3 -0.4 -0.5 -0.6 -0.3 -0.2 -0.6 0.3 -0.2 -0.5 -0.0 -0.2 -0.3 -0.7 -0.8 -0.0 -0.7 -0.2 0.0 -0.2 0.0 -0.1 -0.2 -0.2 -0.3 -0.1 0.2 -0.1 -0.2 -0.2 0.0 -0.5 -0.1 -0.1 -0.2 0.2
Frequency of depressed mood in last 2 weeks 0.2 0.2 4.0 0.3 0.1 0.2 -0.2 0.3 -0.7 -0.0 0.3 0.6 0.3 0.2 -0.2 0.5 0.6 -0.2 2.0 -0.3 0.3 0.8 0.3 0.4 0.7 0.1 0.3 -0.5 -0.6 0.3 0.3 0.4 0.5 0.3 0.5 0.4 -0.3 0.2 0.2 0.3 0.3 0.3 0.7 0.3 0.3 0.3 0.4 0.4 -0.1 -0.2 0.2 0.4 0.3 -0.2
Hearing difficulty/problems: Yes 2.4 3.7 6.8 -1.9 -1.4 -1.9 -1.9 -1.9 1.9 -1.9 -2.0 -2.3 -1.9 -2.0 0.1 -2.0 -1.7 -2.2 -1.6 -1.9 -2.0 -2.2 -2.0 -2.0 -2.1 -2.6 -1.6 -1.5 -1.3 -2.1 -1.8 -2.2 -2.2 -2.0 -2.3 -2.0 1.8 -2.0 -1.9 -2.0 -2.0 -2.0 -2.0 -2.0 -1.9 -2.0 -2.0 -1.8 -1.8 -1.2 -2.0 -2.1 -1.9 -1.9
Relative age of first facial hair 0.1 0.2 4.3 -0.2 0.0 0.1 0.0 -0.2 0.4 -0.8 -0.3 -0.4 -0.2 -0.2 2.1 -0.1 1.4 -0.2 -0.4 -0.2 -0.1 -0.7 -0.2 -0.2 0.2 -0.6 0.0 -0.1 0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.2 0.1 -0.2 -0.2 -0.2 -0.2 -0.2 0.1 -0.1 -0.3 -0.2 -0.2 -0.6 0.5 0.5 -0.2 -0.2 -0.2 0.4
Other serious medical condition/disability diagnosed by doctor 2.4 3.1 6.2 -1.7 -2.5 -1.1 -1.7 -1.8 1.5 -1.8 -1.8 -2.0 -1.8 -1.8 -1.2 -1.7 -0.7 -1.8 -2.2 -2.1 -1.9 -1.6 -1.3 -1.6 -2.0 -2.4 -1.9 -0.9 -0.8 -1.8 -1.7 -1.9 -1.7 -1.7 -2.0 -1.8 1.8 -1.8 -1.7 -1.8 -1.8 -1.8 -2.0 -1.9 -1.6 -1.8 -1.8 -1.4 -1.6 -1.8 -1.7 -1.8 -1.8 -1.6
Ever used hormone-replacement therapy (HRT) 1.1 1.4 3.0 1.2 1.7 1.3 0.9 1.4 -1.2 1.0 1.3 0.9 1.2 1.2 -0.7 1.5 0.3 1.3 0.6 1.6 1.3 0.2 1.2 1.0 0.9 1.4 1.1 1.7 1.5 1.3 1.5 1.2 0.4 1.2 1.0 1.6 -1.4 1.4 1.2 1.3 1.2 1.3 0.3 1.1 0.5 1.3 1.3 1.7 0.6 0.8 1.4 1.2 1.4 0.6
Ever had hysterectomy (womb removed) 0.2 0.2 2.2 -0.3 -0.0 0.0 -0.1 -0.4 0.2 -0.0 -0.2 -0.6 -0.2 -0.2 0.9 -0.1 -0.9 -0.3 -1.1 -0.7 -0.3 -0.6 -0.5 -0.5 -0.0 -0.9 -0.3 -1.5 -0.3 -0.2 -0.8 -0.7 0.1 -0.3 -0.4 -0.0 0.2 -0.2 -0.3 -0.2 -0.2 -0.2 0.4 -0.1 0.0 -0.2 -0.2 -0.1 -0.3 -0.6 -0.3 -0.1 -0.2 -0.3
Systolic blood pressure, automated reading 0.0 0.1 1.4 0.1 0.1 0.4 0.8 -0.0 -0.3 -0.2 -0.0 0.4 0.0 -0.0 0.9 0.0 0.8 0.4 -0.3 -0.6 0.3 0.1 0.4 0.1 0.1 -0.4 0.2 -0.2 1.1 -0.1 0.1 0.4 0.0 0.1 0.3 0.0 -0.1 0.1 0.1 0.0 0.0 0.0 -0.4 0.1 0.1 -0.0 -0.0 -0.5 0.6 1.2 -0.0 -0.1 0.0 0.3
Eye problems/disorders: Diabetes related eye disease 0.4 0.4 3.0 -0.6 -0.1 -0.4 -1.7 -0.3 0.5 -0.7 -0.6 -1.2 -0.5 -0.6 1.0 -0.5 -0.8 -0.6 -0.3 -0.3 -0.8 0.0 -0.6 -0.6 -0.5 0.2 -0.5 0.1 -0.5 -0.6 -0.5 -1.0 -0.7 -0.6 -1.0 -0.4 0.5 -0.6 -0.6 -0.6 -0.6 -0.5 -0.1 -0.5 -0.3 -0.5 -0.5 -0.6 -0.6 -0.9 -0.6 -0.4 -0.6 -0.4
Angina 0.6 0.8 4.5 0.6 0.2 1.1 -0.2 1.0 -0.8 0.0 0.8 0.7 0.8 0.7 -0.9 0.7 1.8 0.8 0.4 0.7 0.4 2.1 0.6 0.9 0.5 1.7 0.5 1.1 1.1 0.8 1.1 0.7 0.8 0.8 0.6 0.8 -0.7 0.6 0.7 0.7 0.8 0.7 1.5 0.8 0.4 0.8 0.7 0.8 0.8 -0.2 0.7 0.9 0.7 1.1
Medication for hormone replacement therapy 0.7 0.8 5.4 -0.8 -0.6 -0.6 -0.5 -0.7 0.8 -1.1 -0.6 -0.8 -0.7 -0.8 0.6 -0.5 0.7 -0.3 0.6 -0.7 -0.8 -2.3 -0.4 -1.1 -0.5 -0.9 -0.5 0.5 0.0 -0.7 -1.1 -1.0 -1.6 -1.1 -0.8 -0.5 0.6 -0.5 -0.8 -0.7 -0.7 -0.6 -1.6 -0.9 -2.3 -0.6 -0.7 -0.2 -0.8 0.3 -0.4 -0.9 -0.5 -0.7
Vitamin and mineral supplements 0.4 0.6 2.0 -0.8 -0.3 -0.9 -0.8 -0.9 0.8 -0.8 -0.8 -0.8 -0.8 -0.7 0.2 -0.8 0.1 -0.7 -0.0 -1.4 -0.7 -0.4 -0.6 -0.8 -0.8 -0.7 -1.0 -0.7 -1.2 -0.8 -0.9 -0.9 -0.9 -0.8 -0.8 -0.9 0.8 -0.8 -0.8 -0.8 -0.8 -0.8 -0.5 -0.7 -0.1 -0.8 -0.8 -0.9 -0.5 -0.5 -0.8 -0.8 -0.8 -0.6
Supplements: Zinc 0.2 0.2 1.0 -0.5 0.1 0.2 -0.2 -0.1 0.2 -0.3 -0.3 -0.6 -0.3 -0.2 -0.6 -0.3 -1.0 -0.2 -0.6 0.6 -0.4 -0.2 -0.6 -0.3 -0.6 -0.6 -0.5 -0.2 0.1 -0.4 -0.1 -0.4 -0.6 -0.5 -0.6 -0.4 0.3 -0.3 -0.3 -0.4 -0.4 -0.3 -0.6 -0.4 -1.0 -0.3 -0.4 -0.3 -0.0 -0.1 -0.2 -0.4 -0.3 0.1
Medication: Co-codamol 1.1 1.3 3.8 -1.1 -0.9 -0.6 -0.6 -1.2 1.1 -1.3 -0.9 -1.2 -1.2 -1.0 0.2 -0.9 -1.7 -1.2 -1.8 -1.3 -1.1 -0.8 -1.2 -1.1 -0.9 -0.8 -1.5 -2.0 0.0 -1.0 -1.6 -1.3 -0.7 -1.1 -1.2 -0.8 1.1 -1.1 -1.2 -1.0 -1.1 -1.0 -0.4 -1.1 -0.2 -0.9 -1.0 -0.5 -1.6 -1.9 -1.1 -0.9 -1.1 -1.5
Medication: Metformin 0.1 0.1 1.6 0.1 0.2 0.2 -0.7 0.2 -0.6 0.1 0.1 -0.3 0.1 0.1 -1.0 0.1 1.3 0.1 1.1 -0.3 0.1 0.5 0.3 0.0 0.2 0.7 -0.2 -0.8 0.3 0.1 0.1 -0.1 -0.1 0.1 -0.2 0.2 -0.1 0.1 -0.0 0.2 0.1 0.2 0.5 0.2 0.3 0.2 0.2 0.1 -0.2 -0.2 0.1 0.2 0.1 -0.2
Diabetes (father) 0.9 1.1 2.8 -1.0 -0.9 -1.5 -0.4 -1.2 1.0 -1.1 -1.1 -0.8 -1.1 -1.1 0.3 -1.1 -1.1 -0.6 -0.7 -1.0 -0.9 -0.4 -1.1 -0.8 -0.9 -1.6 -0.8 -0.3 -1.4 -1.0 -1.1 -0.9 -0.7 -1.0 -0.9 -1.1 1.1 -1.1 -1.1 -1.1 -1.0 -1.1 -1.3 -1.2 -0.7 -1.1 -1.1 -0.4 -1.6 -1.6 -1.1 -1.1 -1.0 -1.7
Diabetes (mother) 0.9 1.2 3.5 1.3 0.4 0.5 0.3 1.0 -0.9 0.8 1.2 0.9 1.2 1.1 0.8 1.2 1.9 1.1 0.8 0.4 0.9 1.0 1.4 1.2 1.2 1.5 1.3 0.8 0.6 1.2 0.5 0.7 0.6 1.1 0.9 1.2 -1.2 1.2 1.2 1.2 1.3 1.2 1.4 1.3 1.4 1.1 1.2 0.9 1.0 1.2 1.1 1.2 1.2 0.8
Severe depression (siblings) 0.1 0.1 1.5 0.0 -0.7 0.1 -0.3 -0.1 -0.2 0.0 0.3 0.0 -0.0 0.3 -1.2 0.5 0.0 0.2 0.7 -0.1 0.2 -0.3 0.2 0.2 0.0 -0.4 -0.5 -0.7 0.3 0.1 -0.3 -0.0 0.2 0.0 0.1 0.3 -0.0 0.3 0.0 0.2 -0.0 0.2 0.1 0.2 0.6 0.3 0.2 -0.2 0.2 0.7 0.1 0.1 0.1 0.2
Pack years adult smoking proportion 0.4 0.6 1.6 -0.9 0.0 -0.4 0.5 -0.7 0.8 -0.8 -0.8 -0.6 -1.0 -1.0 -0.4 -0.7 -1.0 -0.3 -1.1 -0.4 -0.4 -0.8 -0.7 -1.0 -0.8 -0.9 -0.4 -0.2 -0.0 -0.9 -0.5 -0.5 -0.7 -1.0 -0.7 -1.0 0.8 -0.8 -1.0 -0.9 -0.9 -0.8 -0.7 -0.9 -0.3 -0.9 -0.8 -1.0 -0.9 0.1 -1.0 -1.0 -0.9 -1.2
Impedance of leg (right) 0.1 0.6 6.6 -0.6 -0.5 -0.5 -1.4 -0.5 0.7 -0.3 -0.6 -0.1 -0.6 -0.6 -2.6 -0.6 -0.2 -0.8 0.1 -0.6 -0.5 0.5 -0.6 -0.5 -0.8 -0.5 -0.9 -1.1 -0.5 -0.6 -0.3 -0.2 0.4 -0.4 -0.2 -0.8 0.7 -0.7 -0.7 -0.6 -0.6 -0.6 -0.1 -0.6 -0.1 -0.6 -0.6 -0.2 -1.2 -1.7 -0.6 -0.5 -0.6 -1.0
Leg fat-free mass (left) 0.2 1.2 6.8 1.0 1.2 1.0 1.6 0.8 -1.2 0.7 0.9 0.4 1.0 0.9 1.9 1.0 1.4 1.1 0.5 0.8 0.7 -1.3 1.0 1.0 1.0 0.4 1.5 1.2 1.1 0.9 0.7 0.5 -0.2 0.9 0.5 1.0 -1.1 1.1 1.2 1.0 1.0 0.9 0.3 1.0 0.4 0.9 0.9 0.2 2.2 2.6 1.0 0.8 1.0 1.9
Trunk fat percentage 0.0 0.2 1.2 0.1 0.0 -0.0 0.6 -0.2 -0.4 -0.1 0.0 -0.4 -0.0 -0.1 0.7 0.0 -0.2 0.4 -0.6 -0.9 -0.3 -1.1 -0.1 0.1 -0.1 -1.0 0.5 0.5 0.4 -0.0 -0.4 -0.4 -0.7 0.1 -0.3 -0.1 0.0 0.1 0.3 0.0 0.1 -0.1 -0.8 -0.1 -0.2 -0.0 -0.1 0.1 0.4 0.2 0.1 -0.1 0.0 0.5
Hand grip strength (right) 0.1 0.4 3.0 -0.5 -0.6 -0.6 1.7 -0.5 0.5 -0.4 -0.6 -0.2 -0.5 -0.5 -0.9 -0.4 0.4 -0.6 0.9 -0.4 -0.2 -0.6 -0.4 -0.6 -0.2 -0.5 -0.4 0.9 -1.1 -0.6 0.1 -0.1 -0.5 -0.5 -0.3 -0.7 0.5 -0.5 -0.6 -0.5 -0.5 -0.5 -0.2 -0.5 0.3 -0.6 -0.5 -0.7 -0.8 0.2 -0.7 -0.6 -0.5 -1.2
Townsend deprivation index at recruitment 0.2 0.2 4.5 0.1 -0.4 -0.4 -1.6 -0.1 -0.1 0.3 0.1 -0.2 0.1 0.1 -2.1 0.2 -0.4 -0.7 0.6 0.3 -0.1 -0.4 -0.2 0.1 -0.3 0.4 -0.6 -0.5 -0.0 0.1 -0.4 -0.3 -0.1 0.0 -0.1 0.2 -0.1 0.1 0.2 0.1 0.0 0.1 -0.5 0.0 -0.7 0.1 0.0 0.1 0.3 0.3 0.2 0.0 0.1 0.5
Current tobacco smoking 0.3 0.4 3.2 -0.6 -0.8 -0.6 -0.6 -0.3 0.6 -0.9 -0.6 -0.4 -0.6 -0.6 -1.8 -0.4 -0.5 -0.6 -0.9 0.4 -0.5 0.0 -0.5 -0.8 -0.6 -1.2 -0.7 -1.0 -0.5 -0.6 -0.2 -0.3 0.0 -0.6 -0.4 -0.4 0.5 -0.6 -0.7 -0.6 -0.6 -0.6 -0.4 -0.7 -0.8 -0.6 -0.6 -0.2 -0.9 -1.0 -0.6 -0.6 -0.6 -0.7
Average weekly fortified wine intake 0.1 0.2 1.9 0.1 0.1 0.9 -0.4 0.3 -0.4 0.1 0.3 -0.1 0.2 0.4 1.1 0.2 0.0 0.4 -1.4 0.2 0.1 0.2 0.0 0.3 0.3 0.5 0.5 -0.5 0.6 0.2 0.1 0.1 -0.1 0.1 0.1 0.2 -0.1 0.3 0.1 0.2 0.1 0.3 0.4 0.4 0.2 0.3 0.3 -0.2 0.3 0.7 0.2 0.3 0.2 0.3
Maternal smoking around birth 0.1 0.1 1.5 0.1 -0.5 -0.3 0.5 -0.1 -0.1 0.0 0.2 -0.1 0.0 0.1 -0.1 0.2 -1.2 -0.0 0.1 -0.8 -0.2 -0.8 0.1 -0.0 -0.0 -0.6 0.2 0.4 -0.1 0.2 -0.4 -0.2 -0.1 0.1 0.0 0.4 0.0 0.2 0.2 0.2 0.1 0.1 -0.5 0.0 -0.1 0.3 0.0 0.3 0.4 0.2 0.2 0.0 0.1 0.6
Fed-up feelings 0.2 0.3 2.8 -0.3 -0.6 -0.6 -1.0 -0.4 -0.1 -0.5 -0.3 -0.7 -0.4 -0.4 1.0 -0.4 -0.9 -0.5 0.1 -0.2 -0.4 -1.7 -0.2 -0.5 -0.3 -0.3 -0.2 -0.5 -0.1 -0.3 -0.7 -0.7 -0.8 -0.5 -0.6 -0.0 0.2 -0.3 -0.4 -0.3 -0.3 -0.3 -0.6 -0.5 -0.9 -0.3 -0.3 0.1 -0.7 -0.0 -0.2 -0.4 -0.2 -0.7
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.5 1.2 0.7 0.1 0.7 0.3 0.8 -1.0 0.3 0.7 0.6 0.8 0.6 -0.4 0.8 1.1 -0.1 1.0 0.1 0.6 -0.1 0.9 0.9 0.7 0.6 1.0 -0.1 0.6 0.7 0.5 0.6 0.5 0.7 0.6 0.8 -0.8 0.7 0.7 0.7 0.8 0.8 0.6 0.8 0.6 0.6 0.8 0.5 0.6 0.8 0.7 0.8 0.8 0.4
Relative age voice broke 0.1 0.2 0.8 -0.3 -0.6 -0.6 -0.9 -0.5 0.5 -0.5 -0.3 -0.4 -0.3 -0.3 0.3 -0.1 -0.1 -0.2 -0.2 -0.7 -0.4 -0.2 -0.2 -0.4 -0.1 -0.6 -0.4 0.2 -0.6 -0.3 -0.7 -0.5 -0.6 -0.4 -0.2 -0.4 0.4 -0.2 -0.4 -0.3 -0.4 -0.3 -0.7 -0.4 -0.8 -0.3 -0.3 0.0 -0.6 -0.2 -0.2 -0.4 -0.2 -0.5
Taking other prescription medications 2.0 3.1 6.2 -1.7 -2.0 -1.0 -2.4 -1.8 1.6 -1.5 -1.8 -2.5 -1.7 -1.8 -0.7 -2.1 -1.4 -1.6 -2.4 -1.8 -2.0 -1.0 -1.8 -1.7 -2.4 -1.3 -1.6 -2.1 -0.1 -1.8 -2.0 -2.4 -2.0 -1.6 -2.4 -1.8 1.6 -1.9 -1.6 -1.8 -1.7 -1.9 -1.2 -1.7 -1.5 -1.8 -1.9 -1.7 -1.0 -1.7 -1.8 -1.7 -1.9 -0.9
Age when periods started (menarche) 0.1 0.3 2.8 0.4 1.0 0.1 0.5 0.5 -0.4 0.3 0.4 0.6 0.3 0.4 -0.6 0.4 1.7 0.1 0.8 1.3 0.5 -0.1 0.9 0.1 0.2 0.4 0.1 0.9 0.3 0.4 0.7 0.5 0.5 0.2 0.6 0.3 -0.4 0.3 0.3 0.4 0.3 0.3 0.5 0.3 -0.1 0.3 0.3 0.5 0.3 0.3 0.4 0.3 0.3 0.4
Bilateral oophorectomy (both ovaries removed) 0.7 0.8 2.4 -0.9 -0.3 -0.3 -1.4 -0.9 0.9 -0.9 -0.9 -0.8 -0.7 -0.9 -0.3 -0.8 -1.3 -0.8 -1.5 -0.9 -0.7 -1.0 -1.0 -0.9 -0.8 -0.6 -0.5 -1.4 -0.5 -0.9 -1.3 -1.0 -0.7 -0.8 -0.8 -0.8 0.7 -0.8 -0.8 -0.9 -0.8 -0.8 -1.1 -0.8 -1.1 -0.9 -0.8 -0.7 -0.6 -0.6 -0.8 -0.8 -0.8 -0.6
Heel bone mineral density (BMD) T-score, automated (left) 0.1 0.1 1.1 -0.3 -0.4 -0.2 0.5 -0.1 0.3 -0.5 -0.3 -0.3 -0.2 -0.4 -0.2 -0.4 1.0 -0.3 0.3 -0.3 -0.2 0.3 0.1 -0.2 -0.2 -0.2 -0.1 0.5 -0.0 -0.3 0.1 -0.2 -0.4 -0.3 -0.3 -0.3 0.3 -0.3 -0.5 -0.3 -0.2 -0.2 0.3 -0.2 0.2 -0.3 -0.1 -0.4 -0.7 0.0 -0.4 -0.2 -0.3 -1.1
Tinnitus: Yes, but not now, but have in the past 1.5 1.6 3.4 1.4 0.5 1.3 0.3 1.2 -1.4 1.4 1.4 1.3 1.4 1.5 -1.4 1.4 0.4 1.4 0.9 1.0 1.1 -0.3 1.5 1.4 1.1 1.8 1.0 1.8 1.1 1.4 0.9 1.1 1.1 1.3 1.3 1.4 -1.3 1.5 1.5 1.4 1.4 1.4 0.2 1.2 0.2 1.4 1.4 1.8 1.0 1.0 1.6 1.3 1.5 1.2
Qualifications: CSEs or equivalent 0.1 0.1 1.4 0.0 -0.4 -0.1 -0.4 -0.1 0.1 0.1 -0.1 0.2 0.0 -0.1 1.1 0.0 0.1 -0.2 1.2 -0.3 -0.0 -0.2 -0.1 0.0 0.4 -0.2 0.5 0.1 -0.1 -0.1 -0.3 0.0 0.3 0.0 0.2 0.1 -0.0 -0.1 -0.0 -0.0 -0.0 -0.0 -0.2 -0.1 -0.2 -0.1 -0.0 0.3 -0.5 -0.8 0.0 -0.0 -0.0 -0.3
Serious illness, injury or assault to yourself 2.5 3.1 7.5 -1.7 -0.8 -1.4 -2.7 -1.6 1.5 -1.9 -1.8 -2.5 -1.7 -1.9 -1.1 -1.8 -1.1 -1.7 -0.5 -0.6 -2.1 -2.6 -1.8 -1.5 -2.4 -2.6 -1.6 -0.7 -0.9 -1.8 -1.4 -2.2 -2.4 -1.8 -2.3 -1.7 1.6 -1.8 -1.8 -1.7 -1.7 -1.7 -1.2 -1.7 -1.2 -1.8 -1.7 -1.6 -2.0 -1.6 -1.8 -1.7 -1.7 -2.1
High blood pressure 0.6 1.6 4.0 1.2 1.1 1.7 1.3 1.3 -1.0 0.9 1.2 1.4 1.2 1.1 2.0 1.1 1.5 1.1 1.5 0.4 1.2 1.9 1.1 1.2 1.3 1.5 1.0 0.8 1.2 1.2 1.4 1.4 1.5 1.2 1.4 1.3 -1.1 1.1 1.1 1.2 1.2 1.2 1.6 1.4 1.0 1.2 1.3 0.8 1.2 1.0 1.1 1.4 1.2 1.3
Hayfever, allergic rhinitis or eczema 0.4 0.8 4.3 -0.8 -1.4 -0.8 -1.7 -0.7 0.5 -1.2 -0.7 -1.5 -0.8 -0.7 0.4 -0.7 -0.3 -0.9 -0.1 -2.1 -1.3 -0.3 -0.8 -0.7 -1.0 -0.4 -0.7 -1.8 -1.2 -0.7 -1.2 -1.3 -1.3 -0.7 -1.3 -0.6 0.9 -0.7 -0.6 -0.7 -0.8 -0.8 -0.3 -0.6 -0.5 -0.6 -0.8 -1.1 0.4 -0.1 -0.7 -0.7 -0.8 0.6
Multivitamins +/- minerals 1.9 2.5 5.1 1.6 1.3 1.5 1.5 1.7 -1.6 1.5 1.7 1.7 1.7 1.6 0.9 1.6 0.4 1.5 0.7 2.2 1.5 0.7 1.6 1.8 1.7 1.4 1.6 2.0 1.7 1.6 1.8 1.7 1.3 1.6 1.6 1.8 -1.7 1.7 1.7 1.6 1.7 1.7 0.9 1.6 0.9 1.6 1.6 1.6 1.5 1.6 1.7 1.6 1.7 1.4
Stomach or abdominal pain in last month 1.0 1.3 6.8 -1.1 -0.5 -1.0 -1.6 -0.9 0.8 -0.9 -1.0 -1.1 -1.1 -1.0 -0.1 -1.1 -0.3 -0.7 -0.7 -0.1 -1.0 -1.2 -0.9 -1.1 -0.9 -1.2 -1.3 0.5 -0.1 -1.1 -0.4 -1.0 -0.8 -1.1 -1.0 -0.8 0.9 -1.1 -1.2 -1.0 -1.1 -1.0 -1.5 -1.4 -1.9 -1.0 -1.0 0.3 -2.4 -2.6 -0.8 -1.1 -0.9 -2.0
Supplements: Glucosamine 0.8 1.0 2.8 1.1 1.0 1.3 -0.0 1.2 -1.7 0.8 1.0 0.6 1.2 1.1 0.9 1.0 0.8 1.3 0.4 1.6 0.9 0.4 0.8 1.2 1.0 0.7 1.5 0.6 1.3 1.0 1.1 0.8 0.8 1.2 0.7 1.0 -1.2 0.9 1.1 1.0 1.1 1.1 0.9 1.0 0.6 1.0 1.1 1.4 0.5 -0.1 1.1 1.1 1.1 0.7
Diverticular disease/diverticulitis (self-reported) 1.1 1.3 3.3 -1.3 -1.1 -0.9 -1.0 -1.4 0.9 -1.3 -1.4 -1.0 -1.3 -1.4 -0.8 -1.4 -0.4 -1.4 -0.5 -1.0 -1.2 -1.1 -0.9 -1.1 -1.4 -1.5 -1.3 -1.1 -0.4 -1.4 -1.1 -1.0 -1.0 -1.2 -1.2 -1.3 1.2 -1.3 -1.2 -1.3 -1.3 -1.4 -1.0 -1.2 -0.6 -1.4 -1.4 -1.8 -0.4 -0.3 -1.4 -1.3 -1.4 -0.5
Medication: Atenolol 1.3 1.6 3.7 1.2 1.4 1.2 0.9 1.5 -1.4 0.8 1.4 1.2 1.3 1.4 -0.1 1.4 1.5 1.4 0.4 1.1 1.2 1.1 1.2 1.5 1.3 1.9 0.8 1.1 1.0 1.4 1.5 1.3 1.1 1.2 1.2 1.6 -1.3 1.4 1.2 1.4 1.3 1.4 1.5 1.4 1.1 1.4 1.4 1.4 0.9 0.9 1.4 1.4 1.4 1.0
Medication: Levothyroxine sodium 0.5 0.9 1.5 -1.1 -1.0 -1.1 -0.7 -0.9 1.1 -0.9 -1.1 -1.0 -1.0 -1.0 -0.1 -1.1 -0.5 -1.1 -1.2 -1.0 -1.0 -0.3 -0.9 -0.9 -0.8 -0.9 -0.9 -0.5 -0.7 -1.1 -0.8 -0.9 -1.2 -1.0 -1.1 -1.1 1.0 -1.1 -1.0 -1.1 -1.0 -1.1 -0.7 -1.0 -1.0 -1.1 -1.1 -1.2 -0.6 -0.5 -1.1 -1.1 -1.1 -0.7
Sitting height 0.1 0.9 3.1 1.1 0.6 1.2 0.8 1.0 -1.1 1.0 0.9 0.8 1.1 0.8 0.6 0.8 0.9 0.8 0.7 1.4 0.9 -0.5 0.9 1.1 0.9 0.4 1.4 -0.1 0.7 1.0 1.0 0.9 0.5 1.0 0.8 0.7 -0.9 0.9 1.1 0.9 1.1 0.9 1.1 1.1 0.9 0.9 0.9 0.4 1.8 1.6 0.9 0.9 0.9 1.5
Chronic bronchitis/emphysema (father) 0.1 0.1 1.5 -0.1 0.3 0.2 0.9 0.0 0.1 -0.5 0.1 -0.3 -0.0 0.0 1.2 0.0 0.1 0.0 -0.6 -0.2 0.1 -0.2 0.3 -0.1 -0.0 -0.7 0.0 0.1 0.4 0.0 -0.2 -0.2 -0.2 -0.0 -0.2 0.0 -0.1 0.0 0.1 0.0 -0.1 -0.0 -0.0 0.1 -0.2 0.1 -0.0 -0.4 0.7 0.6 0.0 0.0 -0.0 0.8
High blood pressure (mother) 0.1 0.1 1.4 -0.1 -0.8 -0.1 0.4 -0.3 0.2 0.3 -0.1 -0.1 -0.2 -0.1 0.3 -0.0 0.3 -0.3 -0.6 -0.6 -0.2 -0.5 0.3 -0.5 -0.1 1.2 -0.1 -0.9 -0.2 -0.1 -0.5 -0.3 -0.5 -0.2 -0.2 -0.0 0.3 -0.1 -0.3 -0.1 -0.1 -0.1 0.7 0.0 0.8 -0.1 -0.0 -0.3 -0.3 0.0 -0.3 0.0 -0.1 -0.5
Body mass index (BMI) 0.2 0.9 5.2 0.9 1.1 0.6 1.8 0.7 -1.1 0.6 0.7 0.3 0.8 0.7 1.9 0.8 0.2 0.9 -0.1 0.5 0.6 -0.9 0.8 0.8 0.9 0.0 1.3 1.6 0.8 0.7 0.7 0.4 -0.4 0.7 0.4 0.8 -0.8 0.9 1.1 0.8 0.8 0.7 -0.1 0.8 0.2 0.7 0.6 0.3 1.8 2.3 0.8 0.6 0.8 1.6
Impedance of leg (left) 0.1 0.6 5.1 -0.5 -0.6 -0.7 -1.4 -0.5 0.6 -0.2 -0.6 0.1 -0.6 -0.6 -2.3 -0.6 -0.5 -0.7 0.2 -0.8 -0.4 0.7 -0.5 -0.5 -0.6 -0.4 -0.8 -1.0 -0.8 -0.5 -0.3 -0.0 0.5 -0.4 -0.1 -0.8 0.7 -0.7 -0.7 -0.6 -0.5 -0.5 -0.2 -0.7 -0.1 -0.6 -0.5 0.0 -1.5 -1.7 -0.6 -0.5 -0.6 -1.3
Leg predicted mass (left) 0.3 1.3 6.9 1.1 1.2 1.1 1.7 0.9 -1.3 0.8 1.0 0.5 1.1 1.0 1.8 1.1 1.4 1.2 0.5 0.8 0.8 -1.2 1.1 1.1 1.1 0.5 1.6 1.3 1.2 1.0 0.8 0.6 -0.1 1.0 0.6 1.1 -1.1 1.2 1.3 1.1 1.1 1.0 0.3 1.1 0.5 1.0 0.9 0.3 2.2 2.6 1.1 0.9 1.1 2.0
Trunk fat mass 0.1 0.6 2.0 0.8 0.8 0.6 1.4 0.5 -1.1 0.5 0.6 0.2 0.7 0.6 1.3 0.7 0.6 1.0 0.1 -0.2 0.4 -0.9 0.6 0.7 0.6 -0.4 1.2 1.0 0.8 0.6 0.3 0.3 -0.2 0.7 0.3 0.6 -0.6 0.7 1.0 0.7 0.7 0.6 -0.3 0.6 0.3 0.6 0.5 0.5 1.4 1.4 0.7 0.5 0.7 1.3
Waist circumference 0.3 0.9 4.8 0.9 1.1 1.0 1.1 0.8 -1.2 0.5 0.8 0.2 0.8 0.8 2.2 0.9 0.7 1.0 0.4 0.2 0.5 -1.0 0.8 0.8 0.9 0.1 1.4 1.4 1.3 0.8 0.7 0.4 -0.3 0.8 0.4 0.9 -0.9 0.9 1.1 0.8 0.9 0.8 -0.1 0.8 0.1 0.8 0.7 0.4 1.9 2.0 0.9 0.7 0.8 1.9
Number of incorrect matches in round 1.2 2.0 3.2 -1.6 -1.0 -0.8 -0.6 -1.4 1.6 -1.7 -1.6 -1.6 -1.5 -1.4 0.8 -1.4 -1.2 -1.5 -1.8 -1.3 -1.4 -1.2 -1.2 -1.6 -1.2 -1.3 -1.3 -1.4 -0.6 -1.6 -1.3 -1.5 -1.4 -1.6 -1.5 -1.2 1.5 -1.5 -1.6 -1.6 -1.7 -1.5 -1.0 -1.4 -1.3 -1.5 -1.5 -1.7 -1.1 -0.9 -1.6 -1.5 -1.6 -1.1
Past tobacco smoking 0.0 0.1 0.9 0.1 0.5 0.0 0.3 0.2 0.0 0.0 0.2 -0.1 0.1 -0.0 -0.5 0.1 -0.6 0.3 -1.0 0.2 0.1 0.2 0.3 0.2 -0.1 0.1 -0.3 0.5 0.5 0.2 0.2 0.0 -0.3 0.1 -0.1 0.1 -0.3 0.2 0.2 0.1 0.1 0.1 -0.7 0.0 -0.5 0.2 0.1 0.4 0.2 0.4 0.2 0.0 0.2 0.3
Alcohol usually taken with meals 4.0 6.4 12.7 -2.5 -3.4 -2.2 -2.1 -2.9 2.6 -2.5 -2.5 -2.6 -2.6 -2.5 -1.2 -2.7 -1.9 -2.4 -3.6 -2.6 -2.9 -3.0 -2.1 -2.5 -2.9 -2.4 -2.5 -3.0 -1.9 -2.6 -3.2 -2.9 -2.9 -2.6 -2.6 -2.8 2.7 -2.4 -2.4 -2.5 -2.5 -2.6 -2.1 -2.4 -1.7 -2.5 -2.6 -3.0 -1.2 -0.7 -2.6 -2.6 -2.6 -1.5
Nervous feelings 0.2 0.3 2.0 -0.4 -0.2 -0.5 0.1 -0.5 0.3 -0.3 -0.5 -0.4 -0.5 -0.5 0.6 -0.5 -0.8 -0.3 -0.1 -0.8 -0.5 -0.8 -0.7 -0.4 -0.7 0.1 -0.3 -0.5 0.2 -0.5 -0.4 -0.5 -0.8 -0.4 -0.5 -0.5 0.4 -0.4 -0.4 -0.5 -0.5 -0.5 -1.4 -0.7 -0.7 -0.5 -0.5 0.1 -0.9 -0.7 -0.4 -0.7 -0.4 -0.9
Frequency of tenseness / restlessness in last 2 weeks 0.4 0.6 3.9 -0.8 -0.9 -0.3 -0.4 -0.5 0.6 -0.7 -0.8 -0.7 -0.7 -0.8 -0.2 -0.9 -0.4 -0.9 0.5 -1.1 -0.7 -0.1 -0.8 -0.8 -0.6 -1.1 -0.5 -2.0 -0.1 -0.8 -0.4 -0.6 -0.3 -0.6 -0.7 -0.8 0.7 -0.9 -0.8 -0.8 -0.7 -0.8 0.0 -0.6 -0.4 -0.8 -0.7 -0.9 -0.7 -1.2 -0.9 -0.6 -0.8 -0.7
Hearing difficulty/problems with background noise 0.6 1.0 2.3 -0.9 -0.9 -1.0 -0.9 -0.9 0.9 -1.0 -0.9 -1.2 -1.0 -0.9 0.8 -0.9 -1.5 -1.0 -0.8 -0.9 -1.1 -1.1 -1.1 -0.9 -1.0 -1.0 -1.3 -0.7 -0.2 -1.0 -0.9 -1.1 -1.4 -1.0 -1.1 -0.8 0.9 -0.9 -1.0 -0.9 -1.0 -0.9 -1.1 -1.0 -0.8 -0.9 -0.9 -0.6 -1.3 -0.6 -0.9 -1.0 -0.9 -1.4
Hair/balding pattern: Pattern 2 0.2 0.2 5.6 0.0 0.1 0.3 0.3 0.2 -0.3 -0.1 0.1 -0.1 0.1 0.2 2.4 0.1 -0.3 0.5 -0.3 0.5 0.1 -0.8 0.1 0.1 0.3 0.7 0.5 0.6 0.7 0.1 0.2 0.0 -0.4 0.0 -0.1 0.1 -0.2 0.1 -0.1 0.1 0.1 0.1 -0.1 -0.1 -0.4 0.1 0.1 0.6 -0.6 -0.3 0.2 0.0 0.2 -0.6
Had menopause 0.9 1.1 2.4 -1.2 -0.6 0.0 -0.9 -1.0 1.5 -1.1 -1.0 -1.2 -1.2 -0.9 -1.5 -1.0 -1.5 -0.8 -1.2 -0.0 -1.0 -0.5 -1.3 -1.2 -1.2 -1.1 -1.5 -1.3 0.2 -1.0 -0.7 -1.1 -1.2 -1.1 -1.0 -0.9 1.1 -1.0 -1.2 -1.0 -1.1 -1.0 -0.7 -1.0 -0.4 -1.0 -1.0 -0.9 -1.3 -1.1 -1.1 -1.0 -1.1 -1.2
Had other major operations 0.4 0.5 2.8 -0.6 -0.9 -0.9 -0.3 -0.6 0.3 0.1 -0.6 -0.6 -0.5 -0.6 -1.2 -0.5 -1.6 -0.3 -1.5 0.7 -0.6 -1.6 -0.5 -0.4 -0.5 -0.3 -0.7 0.4 -0.6 -0.6 -0.4 -0.5 -1.1 -0.6 -0.6 -0.6 0.5 -0.4 -0.4 -0.6 -0.5 -0.6 -1.7 -0.8 -1.1 -0.6 -0.6 -0.3 -0.4 0.3 -0.4 -0.8 -0.5 -0.5
Forced vital capacity (FVC) 0.1 0.4 4.5 0.2 0.7 -0.4 -0.0 0.2 -0.3 1.1 0.1 0.6 0.2 0.2 -1.3 0.3 0.1 0.1 2.1 1.4 0.5 -1.2 0.3 0.1 0.2 0.3 0.3 0.7 -0.7 0.2 0.5 0.6 0.1 0.1 0.5 -0.0 -0.3 0.3 0.3 0.1 0.2 0.2 -0.9 0.1 -0.5 0.1 0.1 0.1 0.4 1.5 0.3 -0.0 0.3 0.2
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.4 2.4 0.5 -0.1 0.5 1.4 0.5 -0.5 0.2 0.4 0.8 0.5 0.3 0.4 0.4 1.6 0.5 0.4 0.1 0.5 0.4 0.9 0.5 0.5 0.5 0.6 0.8 0.8 0.4 0.8 0.8 0.4 0.4 0.7 0.4 -0.4 0.5 0.2 0.4 0.5 0.5 0.8 0.5 1.0 0.4 0.6 0.3 -0.3 0.6 0.3 0.5 0.5 -0.7
Ever unenthusiastic/disinterested for a whole week 0.1 0.1 0.7 -0.1 0.5 -0.4 -0.4 0.0 -0.0 0.1 -0.2 0.1 -0.0 -0.3 -0.3 -0.2 -0.3 0.0 0.1 -0.1 0.0 -0.4 -0.1 -0.3 -0.1 0.1 -0.2 0.5 -0.9 -0.2 0.2 -0.0 -0.3 -0.2 -0.2 -0.2 -0.1 -0.2 -0.1 -0.1 -0.1 -0.1 -0.2 -0.2 -0.7 -0.2 -0.1 -0.0 -0.2 -0.0 -0.1 -0.2 -0.1 -0.2
Qualifications: None of the above 1.2 2.6 4.7 1.6 2.1 1.8 1.3 1.7 -1.5 1.3 1.8 1.6 1.6 1.8 0.8 1.8 0.6 1.5 2.1 2.2 1.8 0.9 1.3 1.5 2.0 1.1 1.4 2.0 1.7 1.7 1.8 1.7 1.4 1.6 1.7 2.1 -1.8 1.9 1.7 1.7 1.5 1.7 0.5 1.5 0.6 1.8 1.6 1.8 1.5 1.9 1.9 1.5 1.8 1.6
Financial difficulties in last 2 years 0.7 0.9 2.2 -1.0 -1.4 -0.4 -1.5 -0.7 0.9 -1.2 -1.0 -1.1 -0.9 -0.9 -1.0 -0.9 0.5 -0.8 -1.0 -1.4 -0.9 -0.4 -0.6 -1.1 -0.7 -1.0 -0.8 -1.4 -0.6 -1.0 -1.0 -1.1 -0.8 -0.9 -1.0 -0.8 0.8 -1.0 -0.9 -1.0 -1.0 -0.9 -0.7 -0.9 -1.4 -0.9 -0.9 -0.9 -0.7 -1.0 -0.9 -0.9 -0.9 -0.4
Mouth/teeth dental problems 1.8 2.8 4.1 1.7 1.8 1.4 1.7 1.9 -1.6 1.6 1.8 1.8 1.8 1.7 0.1 1.7 1.4 2.0 0.9 1.1 1.8 1.4 2.0 1.5 1.8 1.4 1.8 2.0 1.3 1.7 1.7 1.8 1.8 1.6 1.9 1.9 -1.8 1.8 1.7 1.7 1.7 1.8 1.3 1.8 1.0 1.8 1.8 1.6 1.6 1.6 1.8 1.8 1.8 1.7
Heart attack 1.5 1.9 7.1 1.5 0.7 2.1 0.8 1.4 -1.4 1.3 1.6 1.0 1.5 1.4 -0.1 1.5 0.3 1.4 0.8 0.4 1.1 2.7 0.9 1.5 1.6 1.2 1.2 0.1 1.4 1.5 0.9 1.0 1.6 1.6 1.1 1.6 -1.4 1.3 1.5 1.5 1.5 1.4 2.0 1.6 1.4 1.5 1.5 1.5 1.5 0.3 1.5 1.6 1.4 1.7
Allergy 0.1 0.3 2.0 0.1 0.7 -0.2 0.6 0.1 0.2 0.7 0.0 0.9 0.1 0.1 -0.2 0.2 -0.4 0.0 0.6 1.4 0.6 -0.5 0.2 0.0 0.5 0.1 0.0 1.3 -0.1 0.0 0.6 0.8 0.5 0.0 0.7 -0.0 -0.1 0.1 -0.1 0.1 0.0 0.2 -0.6 -0.2 -0.5 0.0 0.1 0.6 -1.1 -0.2 0.1 -0.1 0.2 -1.1
Pain all over the body in last month 0.3 0.3 1.5 0.4 0.7 0.6 0.2 0.6 -0.6 0.2 0.4 0.3 0.5 0.3 0.6 0.5 0.0 0.7 0.8 1.1 0.5 0.6 0.3 0.5 0.5 -0.1 0.5 1.2 0.1 0.4 0.7 0.4 0.2 0.5 0.3 0.6 -0.7 0.4 0.4 0.4 0.4 0.5 -0.5 0.2 -0.5 0.4 0.4 1.1 -0.5 -0.5 0.6 0.3 0.5 -0.3
Diabetes (self-reported) 0.2 0.4 3.5 -0.4 -0.4 0.1 -1.4 -0.3 -0.0 -0.7 -0.3 -0.8 -0.4 -0.3 0.7 -0.3 1.2 -0.5 0.8 -1.4 -0.5 0.2 -0.4 -0.5 -0.1 -0.2 -0.2 -1.9 0.1 -0.3 -0.5 -0.6 -0.7 -0.3 -0.6 -0.3 0.5 -0.4 -0.4 -0.3 -0.4 -0.3 0.6 -0.1 0.8 -0.2 -0.3 -0.7 -0.2 -0.6 -0.5 -0.1 -0.4 -0.2
Hayfever/allergic rhinitis (self-reported) 1.4 1.8 3.9 1.5 1.7 0.5 1.1 1.5 -1.5 1.4 1.4 1.4 1.5 1.5 0.5 1.4 0.4 1.4 1.1 1.4 1.5 1.0 1.6 1.5 1.3 2.0 1.4 1.3 0.3 1.4 1.5 1.5 1.3 1.4 1.3 1.4 -1.6 1.5 1.5 1.4 1.5 1.4 0.4 1.3 0.7 1.4 1.4 1.6 1.3 1.5 1.5 1.2 1.5 1.2
Medication: Ramipril 1.2 1.6 5.6 1.2 0.9 1.4 0.4 1.3 -1.3 0.6 1.1 1.3 1.3 1.1 1.1 1.1 2.4 1.0 1.4 0.7 1.2 2.0 1.2 1.2 1.3 1.6 1.4 1.3 1.1 1.2 1.3 1.3 1.2 1.2 1.2 1.2 -1.3 1.1 1.3 1.1 1.3 1.1 1.3 1.3 0.6 1.1 1.2 0.8 1.6 1.2 1.2 1.2 1.1 1.6
Medication: Simvastatin 1.5 2.1 5.9 -1.4 -1.6 -0.9 -2.1 -1.6 1.6 -1.8 -1.5 -1.9 -1.5 -1.5 -0.3 -1.4 0.5 -1.4 -1.4 -2.0 -1.5 -0.1 -1.5 -1.3 -1.6 -1.1 -1.2 -2.4 -0.7 -1.5 -2.0 -1.9 -1.5 -1.4 -1.8 -1.5 1.4 -1.5 -1.5 -1.5 -1.5 -1.5 -0.6 -1.3 -0.8 -1.5 -1.4 -1.7 -1.1 -1.2 -1.6 -1.3 -1.5 -1.1
Fluid intelligence score 1.0 2.2 4.1 -1.6 -1.6 -1.8 -1.2 -1.6 1.2 -1.0 -1.7 -1.2 -1.6 -1.6 0.8 -1.8 -1.5 -1.4 -1.4 -1.2 -1.4 -1.4 -1.5 -1.6 -1.3 -0.7 -1.6 -1.6 -2.0 -1.6 -1.4 -1.3 -1.1 -1.6 -1.4 -1.8 1.7 -1.7 -1.6 -1.6 -1.6 -1.6 -0.8 -1.5 -1.2 -1.7 -1.6 -1.8 -1.2 -0.9 -1.7 -1.6 -1.7 -1.3
Illnesses of siblings 0.1 0.1 1.7 0.0 0.1 -0.0 0.0 0.3 -0.3 0.4 0.2 0.3 0.2 0.3 -0.5 0.2 0.4 0.4 1.3 0.3 0.2 0.3 0.5 0.1 0.2 0.2 0.3 0.3 -0.2 0.2 0.1 0.2 0.0 0.1 0.3 0.2 -0.1 0.2 0.2 0.2 0.1 0.2 0.2 0.3 0.1 0.2 0.2 -0.4 0.8 0.9 0.2 0.2 0.1 0.9
Neuroticism score 0.1 0.1 1.3 0.3 -0.5 -0.2 -0.3 -0.0 -0.5 0.2 0.2 -0.2 0.2 0.2 1.2 0.1 -0.5 0.0 0.4 -0.6 -0.0 -0.4 -0.1 0.2 0.2 0.2 0.2 -0.5 0.3 0.2 -0.3 -0.2 -0.2 0.3 -0.1 0.2 -0.2 0.2 0.1 0.2 0.2 0.2 -0.2 0.0 0.1 0.2 0.2 0.7 -0.7 -0.6 0.2 0.1 0.3 -0.7
Weight 0.3 1.6 6.6 1.3 1.4 1.2 1.7 1.1 -1.6 1.0 1.2 0.7 1.3 1.1 1.9 1.2 1.2 1.4 0.5 0.7 1.0 -0.9 1.2 1.3 1.3 0.5 1.9 1.5 1.3 1.2 1.0 0.8 0.0 1.2 0.8 1.2 -1.3 1.3 1.6 1.2 1.3 1.2 0.3 1.2 0.6 1.2 1.1 0.6 2.4 2.6 1.3 1.1 1.2 2.1
Impedance of arm (right) 0.3 1.3 9.5 -1.0 -1.3 -0.6 -2.4 -1.1 1.0 -0.8 -0.9 -0.9 -1.0 -0.9 -2.3 -1.0 -0.1 -0.5 -0.5 -1.8 -1.0 0.6 -1.0 -0.9 -1.3 -1.0 -1.4 -0.8 -0.1 -0.9 -1.3 -1.1 -0.1 -0.9 -0.9 -1.1 1.0 -1.1 -1.0 -1.0 -1.0 -1.0 -0.9 -1.1 -1.0 -0.9 -0.9 0.1 -2.0 -3.1 -0.8 -0.8 -0.9 -1.4
Arm fat percentage (right) 0.1 0.3 2.0 0.4 0.5 0.3 1.1 0.1 -0.6 0.1 0.3 -0.1 0.3 0.3 1.4 0.4 0.3 0.7 -0.2 -0.6 0.1 -0.7 0.3 0.4 0.4 -0.6 0.7 1.2 0.8 0.3 0.1 -0.0 -0.4 0.4 0.0 0.3 -0.3 0.4 0.6 0.4 0.4 0.3 -0.6 0.2 -0.2 0.3 0.2 0.3 1.0 0.9 0.5 0.2 0.4 1.0
Trunk fat-free mass 0.5 2.8 11.0 1.7 1.8 1.7 2.4 1.6 -1.7 1.5 1.5 1.1 1.7 1.6 1.8 1.6 2.0 1.6 0.8 1.4 1.4 -0.5 1.6 1.6 1.5 1.1 2.1 1.1 1.6 1.6 1.5 1.3 0.7 1.6 1.2 1.6 -1.6 1.7 1.9 1.6 1.7 1.5 1.2 1.8 1.2 1.6 1.5 0.6 3.1 3.3 1.6 1.5 1.6 2.8
Hip circumference 0.1 0.5 3.4 0.5 1.0 0.7 0.9 0.3 -0.9 0.2 0.4 -0.1 0.5 0.3 1.8 0.3 -0.1 0.9 -1.0 0.1 0.3 -1.3 0.3 0.6 0.4 -0.1 1.2 0.8 1.1 0.4 0.2 0.0 -0.4 0.5 0.0 0.3 -0.5 0.5 0.8 0.4 0.5 0.4 -0.3 0.5 0.1 0.4 0.3 -0.1 1.6 1.7 0.5 0.3 0.4 1.5
Time employed in main current job 0.3 0.4 2.9 0.4 0.4 0.7 0.4 0.6 -0.4 0.3 0.5 0.4 0.5 0.5 -1.7 0.5 0.7 0.4 0.6 0.5 0.5 0.7 0.6 0.5 0.3 1.0 0.8 0.9 1.0 0.6 0.5 0.4 0.2 0.5 0.4 0.6 -0.6 0.6 0.4 0.5 0.5 0.6 0.8 0.6 0.4 0.6 0.6 0.4 0.3 0.7 0.5 0.6 0.6 0.2
Alcohol intake versus 10 years previously 0.6 0.8 2.8 1.1 1.5 0.5 -0.6 0.9 -1.2 0.4 0.8 0.6 0.9 0.7 0.2 0.9 0.9 0.7 1.5 1.2 1.0 0.5 0.9 1.1 0.8 0.9 1.2 1.6 1.0 0.9 1.2 0.8 0.8 0.9 0.7 1.1 -1.1 0.8 1.0 0.9 1.0 0.8 -0.2 0.6 0.3 0.7 0.8 1.7 0.1 -0.3 1.0 0.7 0.9 0.1
Father’s age at death 0.5 0.6 3.7 0.8 0.8 1.4 1.4 0.7 -0.8 0.7 0.6 1.0 0.7 0.7 0.5 0.4 0.6 1.0 0.0 0.6 0.9 0.7 0.7 0.7 0.5 -0.2 0.7 0.1 1.9 0.7 0.7 0.9 1.2 0.9 0.8 0.5 -0.8 0.6 0.7 0.7 0.7 0.7 0.7 0.7 1.2 0.7 0.7 0.8 0.2 -0.5 0.6 0.8 0.7 0.3
Worrier / anxious feelings 0.1 0.2 1.5 0.3 -0.0 0.2 -0.6 0.2 -0.6 0.4 0.4 0.0 0.3 0.4 0.6 0.4 0.4 0.1 1.2 0.0 0.1 0.2 0.0 0.3 0.3 0.9 -0.2 -0.9 0.8 0.3 0.1 -0.0 0.2 0.3 0.1 0.3 -0.3 0.4 0.3 0.4 0.3 0.3 0.1 0.3 0.5 0.4 0.3 0.7 -0.0 -0.5 0.4 0.4 0.3 0.2
Frequency of tiredness / lethargy in last 2 weeks 0.3 0.5 2.8 -0.6 -0.8 -0.6 -1.4 -0.3 0.7 -0.8 -0.7 -0.9 -0.5 -0.8 -0.4 -0.8 -0.2 -1.1 -0.5 -0.7 -0.9 -0.2 -0.7 -0.6 -0.7 -0.2 -0.2 -1.0 -0.6 -0.7 -0.4 -0.8 -1.1 -0.6 -0.8 -0.7 0.5 -0.8 -0.5 -0.7 -0.6 -0.7 -0.6 -0.6 -1.7 -0.7 -0.7 -0.6 0.1 -0.6 -0.5 -0.6 -0.7 0.4
Falls in the last year 0.2 0.3 2.0 -0.5 -0.2 -0.7 -1.4 -0.5 0.4 -1.1 -0.5 -0.8 -0.6 -0.6 0.4 -0.5 -0.4 -0.4 -1.0 0.2 -0.6 -0.6 -0.4 -0.6 -0.6 -0.0 -0.8 0.3 -0.3 -0.5 -0.3 -0.7 -0.5 -0.6 -0.7 -0.4 0.4 -0.6 -0.5 -0.5 -0.6 -0.5 -0.3 -0.5 -0.3 -0.4 -0.5 -0.5 -0.5 -0.6 -0.5 -0.5 -0.5 -0.4
Hair/balding pattern: Pattern 3 0.1 0.1 0.7 0.2 -0.0 0.4 -0.6 0.3 0.1 -0.1 0.2 0.0 0.2 0.2 -0.5 0.3 0.4 -0.1 0.8 0.1 0.1 0.3 0.3 0.1 0.4 0.7 -0.0 -0.2 -0.0 0.2 0.0 0.1 0.2 0.1 0.1 0.4 -0.2 0.2 0.2 0.2 0.0 0.2 0.3 0.3 0.0 0.3 0.2 -0.2 0.5 0.5 0.2 0.3 0.2 0.7
Number of live births 0.4 0.5 4.4 0.4 0.9 0.6 1.5 0.7 -0.1 0.5 0.6 0.5 0.5 0.6 2.1 0.7 0.6 0.8 0.8 0.8 0.7 0.5 0.7 0.3 0.8 0.7 0.5 1.7 0.3 0.5 0.9 0.6 -0.0 0.3 0.5 0.7 -0.6 0.6 0.3 0.5 0.5 0.6 0.5 0.5 -0.1 0.6 0.6 0.7 -0.0 0.7 0.6 0.5 0.6 -0.0
Forced expiratory volume in 1-second (FEV1) 0.1 0.3 3.1 -0.1 0.4 -0.9 -0.4 -0.1 -0.1 1.0 -0.2 0.1 -0.1 -0.1 -1.3 0.0 -0.2 -0.2 1.8 1.1 0.1 -1.6 -0.0 -0.2 -0.1 0.2 -0.1 0.5 -0.9 -0.1 0.1 0.1 -0.3 -0.2 0.0 -0.4 0.0 0.0 0.0 -0.2 -0.1 -0.1 -1.3 -0.2 -0.8 -0.2 -0.2 -0.2 0.4 1.3 -0.0 -0.4 -0.0 0.2
Pulse rate 0.8 1.3 4.1 -1.3 -1.1 -1.4 -1.2 -1.1 1.4 -0.7 -1.2 -1.1 -1.2 -1.3 1.0 -1.1 0.1 -1.2 -1.1 -0.6 -1.3 -1.6 -1.1 -1.4 -0.9 -0.4 -1.1 -0.3 -1.1 -1.2 -0.8 -1.1 -1.1 -1.3 -1.1 -1.2 1.2 -1.2 -1.1 -1.2 -1.2 -1.3 -1.3 -1.2 -2.0 -1.2 -1.3 -1.3 -0.4 -0.1 -1.1 -1.3 -1.2 -0.3
Happiness 1.1 1.4 7.6 -1.1 -1.3 -1.5 -2.1 -1.3 0.8 -1.2 -1.1 -1.0 -1.2 -1.1 -0.3 -1.2 -0.2 -1.2 -0.9 -0.6 -1.1 -2.8 -0.9 -1.1 -1.2 -1.0 -1.1 -1.4 -0.9 -1.1 -1.5 -1.2 -0.9 -1.1 -1.1 -1.2 1.1 -1.1 -1.1 -1.1 -1.1 -1.2 -0.9 -1.1 -0.6 -1.2 -1.2 -1.4 -0.5 -0.3 -1.2 -1.2 -1.2 -0.7
Noisy workplace 0.1 0.2 1.9 0.0 1.0 0.3 -1.0 0.3 0.1 -0.7 0.0 -0.5 0.1 0.1 0.1 -0.0 0.0 -0.4 -0.3 0.2 -0.1 1.4 -0.5 0.0 -0.0 -0.2 0.5 -0.1 0.4 0.1 0.5 -0.2 -0.1 0.2 -0.4 0.2 -0.3 -0.1 0.0 0.1 0.1 0.0 0.4 0.0 -0.1 0.0 0.1 0.4 -0.3 -1.1 0.1 0.2 0.0 -0.0
Qualifications: A levels/AS levels or equivalent 4.9 10.9 15.7 -3.7 -3.5 -3.8 -3.1 -3.5 3.3 -3.2 -3.4 -3.4 -3.7 -3.2 -1.0 -3.3 -2.0 -3.0 -3.2 -3.1 -3.5 -2.0 -3.2 -3.6 -3.3 -2.9 -4.0 -2.5 -3.9 -3.5 -3.4 -3.5 -3.5 -3.6 -3.4 -3.6 3.7 -3.4 -3.7 -3.5 -3.6 -3.5 -2.7 -3.4 -2.5 -3.4 -3.5 -3.5 -3.1 -2.3 -3.5 -3.5 -3.5 -3.1
Serious illness, injury or assault of a close relative in last 2 years 0.7 0.8 1.8 0.8 0.3 1.2 0.9 0.9 -1.0 1.3 1.0 0.8 0.8 1.0 -0.3 1.0 1.0 1.2 0.0 0.2 0.9 -0.1 1.1 0.7 0.8 1.0 0.6 0.7 0.9 0.9 0.7 0.9 0.7 0.8 0.9 0.9 -0.8 0.9 0.8 0.9 0.8 0.9 0.6 0.9 0.0 0.9 0.9 0.8 1.0 1.2 1.0 0.8 0.9 1.0
Mouth/teeth dental problems: Dentures 0.5 0.8 1.5 -0.9 -0.9 0.0 -1.0 -0.9 0.8 -1.1 -0.9 -1.1 -1.0 -1.0 0.2 -1.0 -1.1 -1.0 -0.4 -0.1 -0.9 -0.3 -1.1 -0.8 -0.9 -0.9 -1.0 -0.8 0.2 -0.9 -0.7 -0.9 -0.9 -0.9 -1.2 -1.0 0.9 -1.0 -0.9 -0.9 -0.9 -0.9 -0.7 -0.9 -0.7 -1.0 -0.9 -0.9 -0.8 -0.6 -1.0 -0.9 -1.0 -0.9
Asthma 0.1 0.3 4.6 -0.1 -0.1 0.3 -0.4 -0.2 -0.1 -0.5 -0.0 -0.8 -0.0 0.0 -2.1 -0.2 0.2 0.1 -0.7 -0.8 -0.4 -0.9 0.1 -0.2 -0.8 -0.5 0.0 -0.7 1.1 -0.1 -0.8 -0.8 -0.5 -0.1 -0.6 0.2 -0.0 -0.0 0.1 -0.1 -0.0 -0.1 -0.1 0.0 -0.1 -0.0 -0.1 -0.4 0.7 0.4 -0.0 -0.1 -0.1 0.7
Medication: Ibuprofen (e.g. Nurofen) 0.1 0.2 1.4 0.3 0.5 0.1 1.2 0.2 -0.3 -0.0 0.2 0.6 0.2 0.2 1.2 0.3 0.3 0.6 -0.6 0.5 0.5 -0.3 0.3 0.4 0.6 0.4 0.1 0.6 -0.2 0.3 0.6 0.6 0.3 0.2 0.5 0.5 -0.2 0.3 0.2 0.2 0.3 0.2 -0.1 0.2 0.2 0.2 0.2 0.2 0.3 0.6 0.2 0.2 0.2 0.1
Medication: Cholesterol lowering 0.2 0.4 2.7 -0.3 -0.9 -0.3 -0.3 -0.4 0.4 -0.7 -0.3 -0.6 -0.5 -0.4 -0.3 -0.4 1.6 -0.6 0.5 -1.4 -0.6 1.4 -0.5 -0.3 -0.3 -0.3 -0.4 -1.4 -0.6 -0.3 -0.6 -0.6 -0.2 -0.4 -0.5 -0.4 0.6 -0.5 -0.4 -0.3 -0.4 -0.4 0.9 -0.2 0.4 -0.3 -0.3 -0.6 -0.0 -0.7 -0.5 -0.2 -0.5 0.1
Depression (self-reported) 3.0 3.6 6.4 -2.0 -1.9 -2.0 -1.4 -1.9 1.9 -1.7 -2.1 -1.8 -2.0 -2.1 -0.5 -2.0 -2.3 -2.1 0.1 -2.5 -1.8 -0.4 -1.9 -1.9 -1.8 -2.2 -1.9 -1.2 -1.9 -2.1 -1.5 -1.6 -2.1 -2.0 -1.9 -2.2 2.0 -2.0 -1.9 -2.1 -2.0 -2.1 -2.4 -2.1 -2.1 -2.1 -2.1 -2.1 -1.3 -0.7 -2.0 -2.2 -2.0 -1.4
Medication: Lansoprazole 0.1 0.2 1.2 0.1 0.3 0.0 0.4 -0.0 -0.2 0.6 0.2 -0.1 -0.0 0.3 0.3 0.3 -0.7 -0.1 0.7 0.0 0.1 -1.1 0.4 -0.1 0.3 0.4 0.2 0.3 0.8 0.1 -0.3 -0.2 -0.8 -0.1 0.0 0.2 -0.2 0.3 -0.0 0.2 0.0 0.2 -0.7 -0.1 -0.5 0.2 0.2 0.7 -0.7 0.3 0.3 -0.1 0.3 -0.7
Prospective memory result 0.3 0.3 4.2 0.3 0.3 0.4 -0.6 0.4 -0.1 0.3 0.3 0.3 0.2 0.3 -2.0 0.3 -0.0 0.5 1.1 -0.0 0.5 1.8 -0.2 0.3 0.5 0.2 0.3 1.4 0.5 0.3 0.7 0.5 0.4 0.3 0.4 0.3 -0.3 0.2 0.2 0.3 0.3 0.3 0.2 0.2 0.2 0.3 0.3 0.7 -0.4 -0.4 0.3 0.3 0.3 -0.3
Lung cancer (father) 1.9 2.2 3.8 1.6 1.3 1.5 0.3 1.5 -1.7 1.0 1.6 1.6 1.5 1.6 -0.1 1.7 1.8 1.5 1.9 1.6 1.6 1.5 1.5 1.6 1.4 1.2 1.1 1.1 1.4 1.6 1.8 1.6 1.5 1.6 1.6 1.6 -1.5 1.5 1.6 1.6 1.5 1.5 1.5 1.6 1.9 1.6 1.5 1.3 1.5 1.0 1.5 1.6 1.5 1.6
Illnesses of mother 1.0 1.3 4.1 1.1 2.0 1.2 0.9 1.3 -0.9 1.3 1.1 1.3 1.1 1.1 0.9 1.2 0.0 0.9 1.2 0.8 1.4 1.6 0.5 1.3 1.4 0.5 1.0 1.3 0.9 1.1 1.6 1.4 1.1 1.1 1.2 1.0 -1.3 1.1 1.2 1.1 1.1 1.1 0.5 1.0 0.5 1.1 1.0 1.0 1.1 1.0 1.1 1.0 1.1 1.2
Forced expiratory volume in 1-second (FEV1), Best measure 0.1 0.3 2.8 0.1 -0.1 -0.8 0.0 0.1 -0.2 1.0 0.1 0.4 0.1 0.2 -0.7 0.3 -0.6 0.0 1.7 0.8 0.3 -1.0 0.1 0.0 0.5 0.5 -0.1 0.6 -1.2 0.1 0.2 0.3 -0.1 0.0 0.4 -0.1 -0.1 0.3 0.2 0.1 0.0 0.1 -1.0 0.0 -0.6 0.1 0.1 -0.1 0.4 1.5 0.2 -0.1 0.2 0.3
Pulse wave Arterial Stiffness index 0.2 0.2 1.5 0.2 0.5 0.5 0.4 0.2 -0.1 0.2 0.2 0.6 0.2 0.2 1.2 0.1 -0.4 0.2 0.1 0.1 0.4 -0.2 0.7 0.1 0.3 -0.1 0.5 0.8 1.2 0.1 0.3 0.5 0.6 0.2 0.5 0.3 -0.3 0.1 0.1 0.2 0.2 0.2 0.2 0.1 -0.2 0.1 0.3 0.6 -0.5 -0.3 0.2 0.2 0.3 -0.5
Impedance of arm (left) 0.4 1.7 11.5 -1.1 -1.7 -1.0 -2.6 -1.3 0.9 -1.1 -1.0 -0.8 -1.2 -1.0 -2.1 -1.1 -0.6 -0.6 -0.4 -1.8 -1.1 0.3 -1.2 -0.9 -1.3 -1.0 -1.7 -1.2 -0.5 -1.0 -1.6 -1.2 -0.2 -1.0 -0.9 -1.2 1.1 -1.2 -1.2 -1.1 -1.1 -1.1 -1.0 -1.3 -0.7 -1.0 -1.0 0.1 -2.5 -3.4 -1.0 -1.0 -1.0 -2.0
Arm fat mass (right) 0.3 1.2 4.9 1.1 1.1 1.1 1.8 0.9 -1.3 0.9 1.0 0.6 1.1 1.0 1.7 1.1 1.0 1.3 -0.0 0.3 0.8 -0.8 1.0 1.1 1.1 0.2 1.6 1.5 1.3 1.0 0.8 0.7 -0.0 1.0 0.7 1.0 -1.1 1.1 1.4 1.0 1.1 1.0 -0.0 1.0 0.5 1.0 0.9 0.6 2.0 2.2 1.1 0.8 1.1 1.8
Trunk predicted mass 0.5 2.8 11.2 1.6 1.7 1.7 2.4 1.6 -1.7 1.5 1.6 1.1 1.7 1.6 1.9 1.6 2.0 1.6 0.7 1.4 1.4 -0.5 1.7 1.6 1.6 1.1 2.1 1.1 1.6 1.6 1.5 1.3 0.7 1.6 1.3 1.6 -1.6 1.7 1.9 1.6 1.7 1.5 1.2 1.8 1.2 1.6 1.5 0.5 3.1 3.4 1.6 1.5 1.6 2.8
Standing height 0.2 1.6 5.4 1.4 1.0 1.6 0.4 1.2 -1.4 1.3 1.2 1.1 1.4 1.3 0.2 1.2 2.3 1.4 1.3 0.8 1.2 -0.1 1.3 1.4 1.0 1.1 1.7 0.1 1.4 1.3 1.0 1.1 1.0 1.4 1.1 1.1 -1.4 1.3 1.5 1.3 1.4 1.3 1.0 1.4 1.1 1.2 1.3 1.0 1.6 1.2 1.3 1.3 1.3 1.5
Length of working week for main job 2.2 2.5 11.2 -1.6 -0.5 -2.3 -0.9 -1.5 1.7 -1.9 -1.6 -1.3 -1.6 -1.6 -0.9 -1.6 -1.8 -1.4 -0.4 0.1 -1.4 -3.3 -1.1 -1.7 -1.6 -0.9 -1.4 0.9 -1.7 -1.6 -1.1 -1.3 -1.7 -1.8 -1.5 -1.3 1.4 -1.4 -1.6 -1.6 -1.6 -1.5 -2.4 -1.8 -2.3 -1.5 -1.6 -1.1 -1.8 -0.3 -1.4 -1.9 -1.4 -2.0
Exposure to tobacco smoke at home 0.1 0.1 0.8 -0.1 -0.2 -0.4 0.4 -0.1 -0.0 -0.1 -0.0 -0.7 -0.1 -0.1 -0.5 -0.1 -0.9 -0.3 -0.2 -0.1 -0.6 -0.6 -0.6 -0.2 -0.5 -0.7 -0.4 0.1 -0.3 -0.0 -0.3 -0.7 -0.6 -0.2 -0.6 0.0 0.1 -0.1 -0.0 -0.0 -0.1 -0.1 0.2 -0.0 0.0 0.0 -0.1 -0.1 0.3 -0.4 -0.0 -0.0 -0.1 0.5
Breastfed as a baby 0.4 0.5 2.6 -0.7 -1.0 -0.7 0.1 -0.6 0.5 -0.1 -0.5 -0.7 -0.7 -0.6 0.3 -0.7 -0.9 -0.6 -1.6 -0.7 -0.8 -0.3 -0.7 -0.6 -0.8 -0.1 -1.0 -0.8 -0.9 -0.6 -0.6 -0.6 -0.7 -0.6 -0.6 -0.6 0.8 -0.5 -0.6 -0.6 -0.7 -0.6 -0.9 -0.7 -0.5 -0.6 -0.7 -0.4 -0.5 -0.6 -0.6 -0.7 -0.6 -0.4
Tense / ‘highly strung’ 0.2 0.3 3.1 0.5 0.1 -0.1 1.3 0.4 -1.0 0.3 0.4 0.6 0.5 0.5 1.1 0.4 0.1 0.5 1.8 -0.4 0.7 0.4 0.2 0.3 0.6 0.2 0.6 0.5 -0.3 0.5 0.2 0.5 0.8 0.5 0.6 0.5 -0.7 0.4 0.5 0.4 0.4 0.4 -0.4 0.2 -0.5 0.4 0.4 1.1 -0.1 -0.3 0.6 0.3 0.5 0.2
Seen doctor (GP) for nerves, anxiety, tension or depression 1.3 2.0 5.6 -1.6 -1.2 -1.2 -1.6 -1.2 1.0 -1.4 -1.5 -1.4 -1.5 -1.4 -0.7 -1.4 -1.2 -1.4 -0.5 -1.5 -1.3 -1.7 -1.4 -1.4 -1.6 -0.7 -1.9 -0.4 -0.6 -1.6 -0.8 -1.2 -2.0 -1.5 -1.5 -1.4 1.3 -1.4 -1.5 -1.5 -1.6 -1.4 -2.4 -1.7 -1.9 -1.4 -1.5 -1.1 -1.7 -0.8 -1.3 -1.7 -1.4 -1.7
Hair/balding pattern: Pattern 4 0.2 0.5 1.8 0.8 1.1 0.3 0.5 0.7 -0.5 0.9 0.6 0.6 0.7 0.5 -0.8 0.6 0.2 0.8 1.4 0.3 0.6 1.2 0.5 0.6 0.6 0.6 0.8 0.8 -0.3 0.7 1.1 0.7 0.8 0.8 0.5 0.5 -0.6 0.6 0.8 0.7 0.8 0.6 0.8 0.7 1.0 0.6 0.6 0.6 1.0 0.4 0.6 0.7 0.6 0.9
Birth weight of first child 1.1 2.0 4.9 -1.4 -1.2 -1.1 -0.4 -1.6 1.1 -1.2 -1.5 -1.6 -1.4 -1.6 -0.3 -1.6 -1.8 -1.2 -1.3 -1.9 -1.4 -2.1 -1.5 -1.2 -1.6 -2.2 -1.1 -0.3 -0.6 -1.5 -1.7 -1.6 -1.4 -1.4 -1.6 -1.5 1.4 -1.4 -1.2 -1.5 -1.3 -1.5 -2.2 -1.6 -1.8 -1.5 -1.6 -1.0 -0.8 -0.9 -1.3 -1.6 -1.4 -0.8
Peak expiratory flow (PEF) 0.1 0.3 3.1 0.2 0.3 -0.7 0.5 0.1 -0.4 0.8 0.1 0.2 0.1 0.3 -0.3 0.3 0.3 0.4 1.4 0.7 0.2 -1.8 0.5 0.0 0.2 0.1 0.1 1.0 -0.6 0.2 -0.0 0.1 -0.3 0.0 0.2 -0.1 -0.2 0.3 0.4 0.1 0.1 0.1 -1.5 -0.1 -1.0 0.1 -0.0 0.2 0.8 1.5 0.3 -0.2 0.2 0.7
Pulse wave reflection index 0.2 0.2 1.3 0.2 1.1 0.7 0.1 0.4 -0.0 0.0 0.2 0.6 0.3 0.3 -0.3 0.3 0.0 0.3 -0.4 0.7 0.6 0.7 0.6 0.2 0.3 0.1 0.6 1.2 1.1 0.1 0.8 0.7 0.3 0.2 0.5 0.3 -0.4 0.2 0.0 0.2 0.2 0.3 0.4 0.2 0.4 0.2 0.3 0.2 -0.5 0.2 0.1 0.3 0.3 -0.6
Ever highly irritable/argumentative for 2 days 0.2 0.2 2.9 0.1 -0.1 0.8 0.8 0.3 -0.3 0.0 0.1 0.4 0.2 0.2 0.2 0.3 0.1 -0.1 1.0 -0.6 0.4 1.7 -0.0 0.1 0.7 0.4 0.3 -0.7 -0.3 0.1 0.3 0.5 0.7 0.2 0.4 0.2 -0.1 0.0 0.0 0.1 0.1 0.2 1.0 0.3 0.5 0.1 0.2 -0.0 -0.2 -0.4 0.0 0.3 0.1 -0.1
Loud music exposure frequency 0.1 0.1 1.3 0.1 -0.2 0.2 -1.2 0.1 0.1 -0.3 -0.0 -0.7 0.1 -0.0 -0.6 -0.1 -0.3 -0.3 -0.5 -0.7 -0.3 -0.7 -0.0 -0.0 -0.5 0.0 0.6 -0.6 0.6 -0.0 -0.2 -0.5 -0.5 0.0 -0.6 0.2 -0.2 -0.0 0.1 -0.0 0.0 -0.0 -0.2 -0.1 -0.2 -0.0 -0.0 0.2 -0.1 -0.3 0.0 -0.0 0.0 -0.1
Qualifications: O levels/GCSEs or equivalent 2.9 4.5 8.6 -2.4 -2.5 -2.4 -1.2 -2.5 1.9 -2.0 -2.3 -1.7 -2.4 -2.1 -0.2 -2.3 -1.1 -2.0 -2.5 -2.3 -2.1 -0.9 -2.0 -2.3 -1.9 -1.8 -2.4 -2.6 -2.9 -2.3 -2.2 -1.9 -1.5 -2.3 -1.8 -2.5 2.6 -2.4 -2.3 -2.3 -2.3 -2.4 -1.1 -2.2 -1.2 -2.3 -2.4 -2.6 -1.6 -1.7 -2.5 -2.3 -2.5 -1.6
Mouth/teeth dental problems: Bleeding gums 0.1 0.1 0.6 -0.2 -0.1 -0.3 0.5 -0.2 0.0 -0.3 -0.2 -0.4 -0.1 -0.1 -0.4 -0.2 0.2 -0.4 0.1 -0.4 -0.4 -0.4 -0.3 0.1 -0.4 -0.2 0.1 -0.8 -0.6 -0.1 -0.3 -0.4 -0.4 -0.1 -0.4 -0.2 0.2 -0.3 -0.1 -0.2 -0.1 -0.2 0.2 -0.1 -0.0 -0.2 -0.2 -0.3 0.1 -0.5 -0.2 -0.1 -0.2 0.2
Blood clot in the leg (DVT) 1.4 1.8 4.9 -1.3 -0.9 -1.3 -1.2 -1.4 1.5 -2.2 -1.4 -1.9 -1.3 -1.4 0.8 -1.3 -0.1 -1.4 -2.2 -1.3 -1.4 -0.6 -1.6 -1.3 -1.2 -1.8 -1.3 -1.2 -1.2 -1.3 -1.5 -1.7 -1.6 -1.3 -1.8 -1.4 1.1 -1.4 -1.3 -1.3 -1.2 -1.4 -0.8 -1.3 -0.6 -1.4 -1.3 -1.4 -1.1 -1.1 -1.4 -1.3 -1.4 -1.3
Medication: Paracetamol 1.5 2.4 5.9 -1.5 -1.2 -0.7 -1.2 -1.5 1.1 -1.6 -1.6 -1.8 -1.5 -1.7 0.3 -1.7 -1.0 -1.6 -2.1 -0.9 -1.6 -2.4 -1.7 -1.7 -1.7 -2.0 -1.0 -1.5 -0.4 -1.6 -1.8 -1.9 -1.5 -1.6 -1.9 -1.4 1.4 -1.7 -1.5 -1.6 -1.6 -1.6 -1.7 -1.7 -2.0 -1.6 -1.6 -1.1 -1.5 -1.9 -1.5 -1.6 -1.6 -1.2
Headache pain in last month 0.7 1.2 6.6 -1.1 -1.4 -0.6 -0.9 -1.2 0.3 -1.1 -1.1 -1.0 -1.2 -1.1 -0.1 -1.2 -1.0 -0.9 -1.2 -0.7 -1.1 -2.6 -1.0 -1.2 -1.2 -0.2 -1.0 -0.9 -0.2 -1.1 -1.3 -1.2 -1.1 -1.2 -1.0 -0.9 1.1 -1.1 -1.1 -1.1 -1.2 -1.1 -1.4 -1.2 -1.7 -1.1 -1.2 -0.6 -1.1 -1.0 -1.0 -1.2 -1.1 -1.0
Medication for cholesterol, blood pressure or diabetes 0.5 0.9 7.8 -0.9 0.0 -1.1 -0.6 -0.8 0.9 -0.2 -0.8 -0.4 -0.8 -0.7 -0.9 -0.8 -2.8 -0.4 -0.7 0.9 -0.4 -1.6 -0.6 -0.9 -0.6 -0.7 -0.9 0.7 -0.7 -0.8 -0.3 -0.4 -0.7 -0.8 -0.5 -0.8 0.5 -0.7 -0.8 -0.9 -0.8 -0.7 -2.2 -1.1 -1.5 -0.8 -0.8 -0.1 -1.5 -0.8 -0.6 -1.0 -0.7 -1.5
Glaucoma (self-reported) 0.1 0.1 1.0 -0.2 0.4 -0.3 0.3 -0.1 -0.0 0.1 -0.1 -0.2 -0.0 -0.1 -0.3 0.0 0.2 -0.2 0.5 0.1 -0.0 -0.7 -0.3 -0.1 -0.1 -0.3 0.2 0.4 0.0 -0.1 -0.0 -0.2 -0.6 -0.3 -0.2 -0.1 0.1 -0.1 -0.2 -0.2 -0.0 -0.1 0.2 -0.1 -0.5 -0.2 -0.1 -0.4 0.3 1.0 -0.2 -0.2 -0.1 -0.0
Gout (self-reported) 0.8 1.2 4.3 -1.0 -0.5 -0.9 -0.4 -0.9 0.9 -1.5 -1.1 -1.6 -0.9 -1.1 0.9 -1.2 -0.8 -1.0 -2.1 -0.3 -1.3 -0.7 -1.1 -1.0 -1.1 -1.4 -0.2 -0.9 -0.7 -1.0 -1.1 -1.5 -1.4 -1.0 -1.5 -0.9 0.8 -1.1 -0.9 -1.1 -1.0 -1.0 -1.2 -1.1 -1.4 -1.1 -1.0 -0.7 -1.0 -1.2 -0.9 -1.0 -1.0 -0.8
Hypothyroidism/myxoedema (self-reported) 1.5 3.0 6.9 -1.8 -1.9 -2.1 -1.6 -1.7 1.8 -1.5 -1.8 -1.9 -1.8 -1.7 0.1 -1.9 -1.8 -1.6 -2.6 -1.7 -2.0 -1.1 -1.7 -1.7 -2.0 -1.1 -1.5 -1.4 -1.4 -1.8 -1.8 -1.9 -2.4 -1.8 -1.9 -1.9 1.8 -1.8 -1.7 -1.8 -1.8 -1.8 -1.4 -1.7 -1.5 -1.8 -1.8 -1.9 -1.1 -0.9 -1.8 -1.8 -1.8 -1.2
Medication: Amlodipine 0.9 1.3 2.7 1.2 0.3 1.4 0.5 1.2 -1.2 1.3 1.1 1.4 1.3 1.2 1.2 1.3 1.2 1.1 0.9 0.8 1.2 0.9 1.1 1.2 1.5 1.0 1.1 0.4 1.0 1.1 0.5 1.1 1.3 1.2 1.3 1.3 -1.1 1.2 1.3 1.2 1.2 1.2 0.9 1.2 0.2 1.2 1.2 1.0 1.5 1.0 1.3 1.2 1.2 1.7
Medication: Ventolin 100micrograms inhaler 0.4 0.5 3.0 -0.4 -0.9 -0.2 -1.0 -0.8 0.5 -0.6 -0.5 -0.9 -0.4 -0.5 -0.4 -0.6 -0.9 -0.4 -1.7 -1.0 -0.6 -0.8 -0.3 -0.5 -0.8 -0.9 0.1 -1.4 0.2 -0.5 -1.4 -1.2 -0.5 -0.5 -0.8 -0.5 0.3 -0.5 -0.4 -0.5 -0.4 -0.5 0.2 -0.3 0.2 -0.5 -0.4 -0.8 -0.0 -0.5 -0.5 -0.3 -0.5 -0.0
Birth weight 0.1 0.3 1.9 0.4 0.8 1.0 1.1 0.5 -0.4 0.3 0.3 0.5 0.4 0.3 -0.5 0.1 -0.1 0.3 0.9 0.2 0.3 1.4 -0.1 0.3 0.3 0.1 0.5 0.2 0.4 0.3 0.9 0.6 0.8 0.5 0.4 0.3 -0.4 0.2 0.5 0.3 0.4 0.2 0.1 0.3 -0.3 0.3 0.2 0.6 0.5 -0.4 0.4 0.3 0.3 0.9
Chronic bronchitis/emphysema (mother) 0.2 0.2 3.5 0.1 -1.9 0.4 -0.2 -0.0 0.2 -0.2 0.1 -0.1 0.2 0.0 0.0 0.1 0.9 0.3 -0.4 -0.5 -0.2 0.3 0.1 0.1 0.4 -0.3 0.1 -0.8 -0.2 0.1 -0.6 -0.3 0.4 0.2 -0.1 0.2 0.0 -0.0 0.3 0.1 0.1 -0.0 0.6 0.3 -0.3 0.1 0.0 -0.5 1.3 0.3 0.1 0.2 -0.0 1.6
High blood pressure (siblings) 0.5 0.7 2.3 0.9 0.5 1.0 1.0 0.7 -0.5 0.8 0.9 0.9 0.8 0.8 1.2 0.9 1.0 0.7 0.4 0.0 0.8 0.2 0.9 0.7 0.8 0.9 0.5 0.5 1.0 0.9 0.6 0.7 1.0 0.7 1.0 1.0 -0.7 0.8 0.6 0.9 0.9 0.9 1.5 0.9 1.2 0.9 1.0 1.1 0.1 0.2 0.8 0.9 0.9 -0.1
Forced vital capacity (FVC), Best measure 0.1 0.4 3.2 0.4 -0.1 -0.4 0.5 0.3 -0.4 1.2 0.3 0.9 0.4 0.4 -1.2 0.6 -0.7 0.3 1.8 0.6 0.6 -0.9 0.4 0.3 0.6 0.3 0.4 0.5 -0.8 0.4 0.2 0.7 0.2 0.3 0.7 0.1 -0.4 0.5 0.4 0.3 0.3 0.4 -0.9 0.2 -0.4 0.3 0.3 0.2 0.6 1.6 0.4 0.1 0.5 0.3
Body fat percentage 0.1 0.2 1.4 0.4 0.5 0.1 0.8 0.1 -0.7 0.1 0.3 -0.1 0.2 0.2 1.2 0.3 0.0 0.6 -0.3 -0.6 0.0 -0.7 0.1 0.4 0.3 -0.7 0.7 0.7 0.5 0.2 0.0 -0.0 -0.4 0.3 -0.0 0.2 -0.2 0.3 0.5 0.3 0.3 0.2 -0.6 0.2 -0.0 0.3 0.1 0.2 0.8 0.7 0.4 0.1 0.3 0.9
Leg fat percentage (right) 0.1 0.3 1.5 0.5 0.9 0.3 1.2 0.4 -0.7 0.3 0.4 0.1 0.4 0.4 1.2 0.4 0.3 0.5 0.1 0.2 0.2 -0.4 0.4 0.4 0.5 -0.5 0.8 0.8 0.5 0.4 0.5 0.3 -0.2 0.4 0.2 0.4 -0.3 0.5 0.6 0.4 0.4 0.3 0.0 0.4 0.4 0.4 0.3 0.0 1.2 1.2 0.4 0.3 0.4 1.0
Arm fat-free mass (right) 0.4 2.2 10.2 1.5 1.6 1.5 2.4 1.4 -1.6 1.3 1.3 1.1 1.5 1.4 2.0 1.4 1.5 1.2 0.8 1.4 1.3 -0.6 1.4 1.4 1.5 0.9 2.0 0.9 1.1 1.4 1.4 1.2 0.5 1.4 1.1 1.4 -1.5 1.5 1.6 1.4 1.5 1.4 1.1 1.6 1.3 1.3 1.3 0.3 2.6 3.2 1.3 1.3 1.4 2.2
Exposure to tobacco smoke outside home 1.5 2.0 6.4 -1.3 -1.9 -1.3 0.0 -1.5 1.3 -1.0 -1.3 -1.4 -1.3 -1.4 -0.1 -1.2 -2.5 -1.4 -1.4 -1.7 -1.6 -1.5 -1.7 -1.6 -1.0 -1.9 -1.2 -1.2 -1.0 -1.3 -1.8 -1.6 -1.4 -1.4 -1.4 -1.1 1.3 -1.3 -1.2 -1.3 -1.3 -1.4 -2.2 -1.6 -2.3 -1.3 -1.4 -0.4 -1.4 -1.7 -1.1 -1.4 -1.2 -1.1
Comparative body size at age 10 0.1 0.3 0.9 0.4 0.7 0.3 0.8 0.4 -0.9 0.7 0.5 0.6 0.5 0.4 0.9 0.5 0.5 -0.0 0.9 -0.2 0.6 0.6 0.2 0.7 0.7 0.2 0.1 -0.1 -0.4 0.5 0.5 0.5 0.7 0.6 0.6 0.6 -0.6 0.4 0.5 0.5 0.5 0.5 0.8 0.6 0.7 0.5 0.5 0.3 0.4 0.1 0.4 0.6 0.5 0.4
Number of full brothers 0.6 0.7 4.1 0.8 1.2 0.3 0.1 1.0 -0.6 0.7 0.7 0.7 0.8 0.7 -1.1 1.0 0.8 0.4 1.7 1.4 0.8 2.0 0.9 0.8 0.6 0.6 0.7 1.4 -0.2 0.8 1.4 0.9 0.7 0.8 0.7 0.9 -0.9 0.8 0.7 0.7 0.8 0.8 0.7 0.8 0.7 0.7 0.8 0.6 0.6 0.7 0.7 0.8 0.8 0.4
Worry too long after embarrassment 0.1 0.2 1.6 0.1 0.2 -0.4 0.7 -0.2 -0.4 -0.3 -0.1 -0.4 -0.1 -0.1 0.6 -0.1 -1.3 -0.4 -0.6 -0.4 -0.2 -0.7 -0.4 0.1 -0.4 -0.1 -0.1 -0.7 0.0 -0.1 -0.1 -0.3 -0.1 0.1 -0.3 0.1 -0.0 -0.2 -0.1 -0.0 -0.0 -0.0 0.4 -0.0 1.1 -0.1 0.0 0.0 -0.8 -1.1 -0.2 0.1 -0.1 -0.8
Seen a psychiatrist for nerves, anxiety, tension or depression 3.4 4.4 8.2 -2.1 -2.7 -2.5 -1.8 -2.2 1.9 -1.4 -2.0 -2.1 -2.2 -2.1 -1.1 -2.0 -2.6 -2.1 -0.0 -2.6 -2.2 -2.3 -2.1 -2.1 -2.1 -2.4 -2.2 -0.8 -1.9 -2.0 -2.1 -2.1 -2.9 -2.2 -2.1 -2.1 2.1 -1.9 -2.1 -2.0 -2.1 -2.0 -2.7 -2.3 -2.3 -2.0 -2.1 -1.4 -2.3 -1.0 -2.0 -2.3 -1.9 -2.5
Wheeze or whistling in the chest in last year 0.2 0.4 2.3 0.7 0.5 0.9 -0.5 0.4 -0.7 -0.2 0.6 0.0 0.7 0.4 -0.6 0.4 1.0 0.7 0.7 -0.3 0.3 -0.3 0.8 0.6 0.1 -0.7 1.3 -0.7 1.5 0.6 -0.3 -0.2 0.4 0.7 0.1 0.9 -0.9 0.5 0.8 0.6 0.8 0.6 0.6 0.6 0.5 0.5 0.6 0.7 0.8 -0.1 0.6 0.7 0.6 0.9
Number of children fathered 0.3 0.3 2.2 0.5 0.6 0.6 1.5 0.2 -0.6 0.3 0.5 0.6 0.5 0.4 0.5 0.6 0.4 0.8 0.2 -0.4 0.5 -0.5 0.6 0.5 0.6 0.3 0.3 0.4 0.3 0.5 0.1 0.3 0.4 0.5 0.5 0.5 -0.3 0.5 0.5 0.5 0.5 0.5 0.5 0.5 1.1 0.5 0.5 0.2 0.5 0.9 0.4 0.5 0.5 0.3
Reason for reducing amount of alcohol drunk: Health precaution 2.5 3.0 6.6 -1.7 -1.8 -1.6 -1.1 -1.7 1.9 -1.5 -1.7 -1.8 -1.7 -1.7 0.9 -1.6 -2.1 -1.7 -2.6 -2.4 -1.8 -0.5 -1.6 -1.9 -1.5 -1.8 -1.6 -2.0 -1.9 -1.7 -1.8 -1.7 -1.8 -1.6 -1.8 -1.9 1.6 -1.7 -1.8 -1.7 -1.7 -1.7 -1.5 -1.7 -1.1 -1.7 -1.7 -1.3 -1.9 -1.9 -1.7 -1.7 -1.7 -1.9
Age at first live birth 0.6 1.0 3.3 -0.9 -1.8 -1.5 -0.2 -1.2 0.8 -0.6 -0.8 -1.0 -1.0 -0.9 -1.1 -1.1 -0.5 -0.6 -1.3 -1.3 -1.2 -0.9 -1.0 -0.7 -1.2 -1.3 -1.3 -1.6 -1.1 -0.8 -1.5 -1.2 -0.7 -0.9 -1.0 -1.0 1.1 -1.0 -0.9 -0.9 -0.8 -1.0 -0.1 -0.8 -0.1 -0.9 -1.0 -1.1 -0.4 -0.8 -1.0 -0.9 -1.0 -0.4
Pulse wave peak to peak time 0.1 0.1 1.5 -0.1 -0.3 -0.3 -0.2 -0.1 -0.0 -0.2 -0.0 -0.5 -0.1 -0.1 -1.2 0.1 0.6 -0.1 0.0 0.1 -0.3 0.1 -0.5 0.0 -0.3 0.2 -0.3 -0.7 -1.0 0.0 -0.2 -0.4 -0.6 -0.1 -0.4 -0.2 0.1 0.0 0.1 -0.0 -0.0 -0.1 -0.1 0.1 0.3 0.0 -0.1 -0.4 0.8 0.4 -0.0 -0.0 -0.1 0.8
Health satisfaction 0.4 0.5 1.9 0.7 0.7 0.1 -0.6 0.7 -0.8 0.9 0.8 0.4 0.6 0.6 0.3 0.6 -0.1 0.8 1.2 0.7 0.5 -0.7 1.0 0.7 0.5 -0.0 0.7 1.1 0.3 0.8 0.4 0.4 -0.1 0.5 0.4 0.9 -0.7 0.8 0.8 0.8 0.7 0.7 -0.2 0.5 -0.7 0.8 0.6 1.0 0.9 1.4 0.9 0.5 0.8 1.0
Shortness of breath walking on level ground 0.5 0.6 2.6 0.8 1.6 0.7 -0.5 0.8 -0.7 0.4 0.7 0.6 0.8 0.6 -0.7 0.7 1.4 0.7 0.4 0.9 0.8 0.3 0.9 0.6 0.6 0.4 0.9 0.4 0.3 0.7 0.7 0.6 0.5 0.7 0.6 0.8 -1.0 0.7 0.8 0.8 0.8 0.8 1.2 0.9 0.6 0.7 0.8 0.2 1.3 1.6 0.7 0.8 0.7 1.1
Qualifications: College or University degree 0.8 2.5 5.4 -1.7 -1.5 -2.0 -2.0 -1.6 1.6 -0.9 -1.7 -1.6 -1.5 -1.6 -0.4 -1.8 -1.3 -1.1 -1.8 -1.2 -1.7 -1.3 -1.4 -1.6 -1.7 -0.8 -1.8 -0.5 -1.4 -1.7 -1.3 -1.5 -2.1 -1.6 -1.6 -1.9 1.6 -1.6 -1.5 -1.7 -1.6 -1.7 -2.0 -1.7 -2.3 -1.7 -1.7 -1.5 -1.1 -0.7 -1.5 -1.8 -1.6 -1.2
Eye problems/disorders: None of the above 0.7 0.8 2.7 1.0 -0.2 0.9 -0.4 0.9 -1.0 1.3 1.0 1.1 1.0 0.9 -0.3 0.8 1.2 0.8 1.6 -0.1 0.6 0.4 0.8 0.8 0.9 1.1 1.0 0.1 0.4 1.0 0.5 0.9 0.9 1.0 1.0 0.8 -0.8 0.9 1.1 1.0 1.0 0.9 0.7 1.0 0.5 1.0 0.9 0.9 1.2 0.6 1.0 1.0 0.9 1.4
Mouth/teeth dental problems: Loose teeth 0.1 0.1 1.4 0.3 -1.2 -0.2 0.1 0.1 -0.4 0.3 0.3 -0.3 0.2 0.3 0.4 0.4 -0.2 0.4 -0.2 -0.5 -0.0 -0.5 -0.0 0.3 0.4 -0.1 0.2 -0.2 -0.3 0.3 -0.2 -0.2 -0.1 0.3 -0.1 0.3 -0.2 0.3 0.3 0.3 0.3 0.3 0.1 0.2 0.1 0.3 0.3 0.3 0.5 0.5 0.3 0.2 0.3 0.4
Emphysema/chronic bronchitis 2.6 2.9 6.8 1.7 1.5 2.4 1.3 1.9 -1.6 1.2 1.7 1.6 1.8 1.8 1.4 1.7 1.3 1.9 1.2 2.3 1.7 0.9 1.8 1.7 1.9 1.4 2.0 2.3 2.6 1.7 1.8 1.6 1.5 1.7 1.6 1.9 -1.9 1.7 1.6 1.7 1.8 1.8 1.6 1.7 1.4 1.7 1.8 2.1 0.7 0.5 1.8 1.8 1.8 0.7
Medication for pain relief, constipation, heartburn 1.2 2.1 4.6 1.5 1.1 1.3 0.6 1.4 -1.1 2.1 1.6 1.8 1.5 1.7 -0.3 1.4 0.6 1.6 1.7 0.9 1.6 1.9 1.7 1.4 1.5 1.5 1.0 1.1 1.4 1.5 1.3 1.7 1.8 1.6 1.8 1.1 -1.4 1.5 1.5 1.5 1.5 1.5 1.2 1.5 1.3 1.6 1.5 1.4 1.4 1.1 1.6 1.5 1.5 1.4
Neck or shoulder pain in last month 1.6 2.3 5.1 -1.5 -0.8 -1.9 -2.3 -1.4 1.3 -1.8 -1.6 -1.7 -1.5 -1.7 -0.6 -1.7 -1.8 -1.5 -1.6 -0.9 -1.5 -1.0 -1.5 -1.5 -1.6 -0.2 -1.4 -0.4 -1.4 -1.6 -1.1 -1.6 -1.4 -1.5 -1.7 -1.8 1.3 -1.7 -1.6 -1.6 -1.5 -1.6 -1.4 -1.6 -1.5 -1.6 -1.6 -1.1 -1.9 -2.2 -1.5 -1.5 -1.5 -1.7
Medication: Blood pressure 0.9 1.6 5.5 1.2 0.8 1.7 1.4 1.4 -1.4 0.6 1.3 1.0 1.2 1.1 1.4 1.2 2.3 0.9 0.8 0.4 1.0 1.1 0.9 1.2 1.3 1.2 1.3 0.5 1.2 1.2 1.1 1.1 0.9 1.1 1.1 1.4 -1.0 1.2 1.2 1.3 1.2 1.2 2.0 1.5 1.5 1.3 1.2 0.3 1.9 2.0 1.1 1.3 1.1 1.7
Angina (self-reported) 0.6 0.8 4.4 0.6 0.3 1.2 -0.4 1.0 -0.7 -0.1 0.8 0.7 0.7 0.7 -1.3 0.6 2.0 0.8 0.4 0.7 0.4 2.1 0.6 0.9 0.4 1.7 0.6 1.0 1.2 0.8 1.1 0.7 0.8 0.8 0.6 0.8 -0.7 0.5 0.7 0.7 0.7 0.7 1.5 0.8 0.4 0.7 0.7 0.8 0.8 -0.2 0.7 0.9 0.6 1.1
Migraine (self-reported) 0.1 0.2 2.7 -0.2 -0.1 -0.6 0.3 -0.2 -0.1 -0.5 -0.3 -0.3 -0.2 -0.2 -0.7 -0.2 -1.2 -0.0 -1.6 0.2 -0.3 -0.1 -0.3 0.0 -0.5 -0.1 -0.2 -0.3 -0.4 -0.2 -0.2 -0.3 -0.4 -0.2 -0.4 -0.2 0.1 -0.3 -0.2 -0.2 -0.2 -0.3 -0.4 -0.4 -0.5 -0.3 -0.3 0.3 -0.4 -0.9 -0.2 -0.3 -0.2 -0.2
Medication: Ibuprofen 0.1 0.1 0.9 -0.1 0.1 -0.3 0.7 -0.2 0.2 -0.5 -0.1 0.2 -0.2 -0.2 0.5 0.0 -0.4 0.1 -0.9 0.5 0.2 -0.7 0.1 0.1 0.2 0.2 -0.3 0.5 -0.4 -0.1 0.1 0.1 -0.1 -0.1 0.1 0.3 0.0 -0.0 -0.2 -0.1 -0.1 -0.1 -0.7 -0.3 -0.1 -0.1 -0.1 0.2 -0.6 -0.0 -0.1 -0.2 -0.0 -0.8
Medication: Allopurinol 1.3 1.7 5.9 -1.3 -0.9 -1.0 -0.7 -1.1 1.5 -1.8 -1.4 -1.7 -1.2 -1.5 0.6 -1.6 -0.5 -1.2 -2.4 -0.3 -1.5 -0.5 -1.3 -1.2 -1.3 -1.3 -0.3 -0.7 -0.7 -1.4 -1.0 -1.4 -1.8 -1.3 -1.6 -1.3 1.1 -1.5 -1.3 -1.4 -1.3 -1.4 -1.2 -1.3 -1.7 -1.5 -1.4 -1.3 -1.0 -1.0 -1.3 -1.3 -1.3 -1.0
Medication: Omeprazole 3.6 4.3 7.1 -2.1 -2.4 -2.1 -2.1 -2.2 2.1 -2.3 -2.1 -2.0 -2.1 -2.1 -1.4 -2.1 -1.3 -2.2 -2.6 -1.1 -2.2 -2.0 -2.3 -1.9 -2.3 -1.5 -2.0 -1.3 -1.5 -2.2 -2.2 -2.2 -1.6 -2.1 -2.0 -2.2 2.2 -2.1 -2.3 -2.2 -2.1 -2.1 -1.8 -2.2 -1.3 -2.1 -2.0 -1.8 -2.6 -2.2 -2.2 -2.1 -2.1 -2.7
Medication: Seretide 50 evohaler 0.3 0.3 2.7 0.3 0.8 0.4 0.7 0.5 -0.2 0.6 0.4 0.1 0.4 0.5 -1.6 0.5 -0.0 0.6 1.2 1.1 0.4 1.1 0.5 0.3 0.0 -0.4 0.3 1.5 -0.0 0.4 0.6 0.3 0.2 0.4 0.2 0.4 -0.4 0.5 0.4 0.4 0.4 0.4 -0.0 0.3 0.2 0.4 0.4 0.5 0.3 0.4 0.5 0.3 0.4 0.3
Mean time to correctly identify matches 0.7 1.3 2.7 -1.2 -0.6 -1.1 -1.2 -1.1 1.1 -1.3 -1.2 -1.3 -1.2 -1.3 -0.5 -1.2 -0.0 -1.6 -0.6 -0.6 -1.3 1.4 -1.6 -1.0 -1.1 -0.7 -1.6 -1.6 -0.7 -1.2 -0.8 -1.2 -0.6 -1.1 -1.3 -1.2 1.2 -1.3 -1.2 -1.2 -1.2 -1.2 -0.4 -1.1 -0.4 -1.2 -1.2 -1.2 -1.0 -1.4 -1.3 -1.1 -1.3 -1.0
Heart disease (mother) 0.4 0.5 4.1 -0.5 -1.5 -0.6 -0.7 -0.5 0.5 -0.8 -0.5 -0.6 -0.5 -0.4 -0.9 -0.3 -0.5 -0.1 -0.9 -0.2 -0.6 -2.0 -0.3 -0.7 -0.5 -0.4 -0.7 1.2 -0.4 -0.5 -0.8 -0.7 -1.0 -0.6 -0.6 -0.3 0.5 -0.3 -0.4 -0.5 -0.5 -0.4 -1.7 -0.7 -1.9 -0.4 -0.5 0.0 -0.4 0.3 -0.2 -0.7 -0.3 -0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria 2.9 3.4 8.9 -2.0 -1.2 -1.8 -1.0 -2.2 1.9 -1.5 -2.1 -1.3 -2.0 -2.0 0.2 -1.9 -2.0 -2.2 -0.0 -1.1 -1.4 -1.2 -1.6 -2.0 -1.5 -1.4 -2.0 -0.0 -1.8 -2.0 -1.8 -1.5 -1.4 -2.0 -1.5 -1.9 1.8 -1.9 -2.1 -2.0 -1.9 -1.9 -3.0 -2.4 -2.6 -2.0 -2.0 -0.9 -2.8 -1.7 -1.8 -2.3 -1.8 -2.8
Whole body fat mass 0.2 1.0 3.2 1.0 1.1 0.8 1.6 0.8 -1.3 0.6 0.9 0.5 0.9 0.8 1.7 0.9 0.8 1.2 0.1 0.2 0.7 -0.6 0.9 1.0 1.0 -0.1 1.5 1.2 1.0 0.9 0.7 0.6 0.0 0.9 0.6 0.9 -0.9 1.0 1.2 0.9 1.0 0.9 -0.0 0.9 0.4 0.9 0.8 0.6 1.8 1.8 1.0 0.8 0.9 1.7
Leg fat mass (right) 0.3 1.0 5.1 1.0 1.3 0.7 1.8 0.8 -1.2 0.7 0.9 0.5 0.9 0.9 1.6 1.0 0.9 1.1 0.2 0.5 0.7 -0.8 0.9 0.9 1.0 0.1 1.4 1.2 0.9 0.9 0.9 0.6 -0.1 0.9 0.6 0.9 -0.9 1.0 1.2 0.9 1.0 0.9 0.2 0.9 0.6 0.9 0.8 0.3 2.0 2.3 0.9 0.8 0.9 1.7
Arm predicted mass (right) 0.4 2.0 9.7 1.5 1.4 1.3 2.1 1.3 -1.5 1.3 1.3 0.9 1.4 1.3 1.9 1.4 1.2 1.2 0.4 1.2 1.2 -0.8 1.3 1.4 1.4 0.9 1.9 0.9 1.0 1.3 1.2 1.1 0.4 1.4 1.0 1.3 -1.4 1.5 1.6 1.4 1.5 1.3 0.9 1.5 1.2 1.3 1.3 0.4 2.6 3.1 1.3 1.2 1.3 2.2
Pulse rate, automated reading 0.1 0.2 3.2 -0.3 -0.3 0.0 0.4 -0.4 0.3 0.1 -0.2 -0.2 -0.4 -0.4 1.8 -0.2 -0.2 -0.2 -1.1 -0.2 -0.3 -1.2 -0.2 -0.5 0.2 -0.3 -0.8 -0.3 0.3 -0.3 -0.2 -0.2 -0.0 -0.4 -0.2 -0.3 0.4 -0.2 -0.3 -0.3 -0.3 -0.3 -0.7 -0.4 -0.7 -0.2 -0.3 0.0 -0.3 -0.2 -0.2 -0.4 -0.2 -0.2
Alcohol intake frequency. 3.3 7.6 14.5 2.9 2.6 2.9 2.4 2.7 -2.8 2.5 2.8 3.1 2.8 2.8 1.5 2.8 2.2 2.7 3.8 3.2 3.2 2.7 2.8 2.9 3.1 2.4 2.6 3.0 3.1 2.9 2.9 3.0 3.1 2.9 3.0 3.1 -3.1 2.8 2.8 2.9 2.9 2.8 1.5 2.5 1.8 2.8 2.8 3.4 1.7 1.3 3.0 2.7 2.9 1.8
Comparative height size at age 10 0.0 0.1 1.8 0.2 -0.2 0.5 -0.6 0.0 -0.3 0.1 0.2 -0.0 0.2 0.1 1.3 0.1 0.7 -0.1 0.0 -0.7 0.0 -0.0 -0.1 0.4 0.5 1.0 0.1 -0.1 0.3 0.2 -0.0 -0.0 0.1 0.3 0.0 -0.0 -0.2 0.1 0.1 0.2 0.3 0.2 0.3 0.1 0.5 0.2 0.2 0.5 -0.3 -0.7 0.1 0.2 0.2 -0.3
Number of full sisters 0.2 0.3 2.7 0.2 -0.3 -0.3 0.9 -0.1 -0.2 0.1 0.2 0.6 0.1 0.2 1.6 0.4 -0.8 0.1 -0.8 -0.5 0.3 -1.2 0.7 0.2 0.5 -1.6 0.2 0.7 -0.2 0.2 -0.3 0.3 0.0 0.1 0.5 0.3 -0.2 0.3 0.2 0.2 0.2 0.2 -0.6 0.1 0.1 0.2 0.2 0.0 0.3 1.1 0.2 0.0 0.3 -0.0
Suffer from ‘nerves’ 0.1 0.2 1.3 0.1 -0.9 -0.4 -0.9 -0.3 -0.2 0.2 -0.1 -0.3 -0.2 -0.2 0.5 -0.1 -0.5 0.3 0.8 -1.1 -0.2 -0.7 -0.3 -0.0 -0.5 -0.3 -0.1 0.5 0.5 -0.1 -0.2 -0.3 -0.6 -0.2 -0.3 -0.2 0.2 -0.1 -0.0 -0.0 -0.0 -0.1 -1.1 -0.4 -0.5 -0.1 -0.2 0.5 -0.4 -0.1 -0.0 -0.3 -0.0 -0.5
Overall health rating 0.7 1.5 4.1 1.4 1.1 0.9 -0.2 1.3 -1.6 1.1 1.3 0.9 1.4 1.2 0.0 1.4 0.4 1.2 2.0 1.1 1.0 -0.2 1.4 1.4 0.9 0.4 1.6 1.9 1.5 1.3 1.0 0.8 0.6 1.3 0.9 1.7 -1.6 1.4 1.5 1.3 1.4 1.4 -0.3 1.0 -0.2 1.3 1.3 2.0 0.7 0.8 1.6 1.1 1.5 0.9
Chest pain or discomfort 0.1 0.1 2.2 0.0 0.0 0.6 -0.3 0.2 -0.3 0.0 0.1 -0.3 0.1 -0.0 1.2 -0.0 0.6 0.1 1.5 -0.2 -0.3 0.1 -0.0 0.1 -0.1 -0.7 -0.1 -0.1 0.9 0.1 -0.0 -0.3 -0.2 0.0 -0.2 0.4 -0.1 0.0 0.1 0.1 0.1 0.1 0.2 0.1 -0.3 0.1 0.1 0.2 0.2 -0.4 0.1 0.2 0.1 0.5
Had major operations 0.4 0.4 2.1 0.4 0.5 1.1 0.6 0.6 -0.5 0.2 0.6 0.3 0.5 0.5 -0.1 0.8 0.7 0.9 0.5 0.3 0.6 1.0 0.7 0.8 0.7 -0.3 0.5 1.0 0.9 0.5 0.6 0.5 0.0 0.5 0.4 0.7 -0.5 0.6 0.7 0.6 0.4 0.5 0.1 0.6 0.1 0.7 0.5 0.2 1.3 1.1 0.6 0.5 0.5 1.4
Age at last live birth 0.1 0.1 1.5 -0.1 0.3 -0.9 1.2 0.1 0.1 0.6 0.0 -0.1 -0.0 -0.0 0.6 -0.3 -0.3 0.4 -0.9 0.8 -0.1 0.2 -0.2 -0.0 0.1 0.6 -0.3 0.2 -0.6 0.1 0.2 -0.1 -0.0 -0.1 -0.1 -0.1 0.1 -0.1 -0.1 -0.0 -0.0 -0.0 0.1 -0.1 -0.5 -0.0 -0.1 0.1 -0.1 -0.2 0.0 -0.1 -0.0 0.0
Family relationship satisfaction 0.4 0.5 3.2 0.6 0.5 0.4 -0.0 0.6 -0.7 -0.1 0.6 0.3 0.6 0.7 1.4 0.4 1.8 0.0 1.0 -0.2 0.5 -0.2 0.6 0.4 0.2 1.4 0.8 -1.2 0.1 0.6 0.2 0.4 1.0 0.7 0.4 0.7 -0.5 0.5 0.6 0.6 0.6 0.5 1.3 0.8 1.2 0.6 0.6 0.2 1.0 0.1 0.5 0.8 0.5 1.1
Leg pain on walking 0.6 0.7 7.0 0.7 1.2 0.6 0.8 0.8 -0.7 0.3 0.8 0.7 0.7 0.7 2.6 0.9 0.4 0.9 0.9 1.6 0.8 0.0 0.9 0.7 0.8 0.9 0.7 1.3 0.3 0.8 0.8 0.8 0.3 0.5 0.8 1.1 -0.8 0.8 0.6 0.8 0.8 0.8 0.4 0.6 -0.0 0.8 0.7 1.0 0.5 1.0 0.8 0.6 0.8 0.4
Qualifications: NVQ or HND or HNC or equivalent 0.5 0.6 1.1 -0.8 -0.7 -0.7 -0.4 -0.8 0.8 -1.0 -0.9 -0.7 -0.9 -0.8 0.7 -0.9 0.1 -1.0 -0.8 0.1 -0.8 0.2 -1.0 -0.7 -0.6 -0.4 -0.6 -0.1 -0.9 -0.9 -0.4 -0.7 -0.5 -0.8 -0.8 -0.9 0.9 -0.9 -0.9 -0.8 -0.9 -0.9 -0.3 -0.8 -0.2 -0.9 -0.9 -0.9 -0.7 -0.9 -0.9 -0.8 -0.9 -0.7
Commuting to job workplace: Car/motor vehicle 0.5 0.5 3.4 0.5 0.9 0.5 1.3 0.7 -0.6 0.7 0.6 0.7 0.5 0.6 1.6 0.7 0.0 1.2 0.5 0.2 0.8 0.6 0.9 0.3 1.0 1.1 0.7 1.8 -0.3 0.6 0.9 0.8 0.3 0.4 0.7 0.7 -0.6 0.6 0.4 0.6 0.5 0.6 0.1 0.4 -0.3 0.6 0.6 1.1 -0.1 0.4 0.7 0.5 0.7 -0.1
Illness, injury, bereavement, stress in last 2 years 2.2 2.7 6.6 1.9 1.9 1.0 2.4 1.5 -1.6 1.9 1.6 2.0 1.7 1.5 1.4 1.4 -0.2 1.2 0.5 1.5 1.8 2.6 1.1 2.0 1.8 1.8 1.8 0.6 0.7 1.6 1.6 1.9 2.1 1.9 1.9 1.5 -1.7 1.5 1.9 1.6 1.7 1.5 1.1 1.6 1.6 1.5 1.5 1.4 1.9 1.0 1.6 1.6 1.6 1.9
Medication: Aspirin 0.1 0.1 1.0 0.3 0.2 0.4 0.6 0.4 -0.2 -0.5 0.2 -0.3 0.3 0.2 0.5 0.2 1.0 -0.1 0.4 0.0 0.0 0.4 0.0 0.3 0.3 0.4 0.4 0.2 0.2 0.2 0.4 -0.0 -0.3 0.2 -0.2 0.3 -0.2 0.1 0.2 0.2 0.2 0.2 0.9 0.4 0.3 0.2 0.3 -0.1 0.4 0.4 0.1 0.3 0.2 0.4
Supplements: Vitamin C 0.0 0.1 0.5 0.0 -0.7 0.3 0.3 0.2 -0.2 0.2 0.0 0.2 0.1 0.0 0.2 0.1 0.1 0.1 -0.2 -0.2 0.0 0.6 -0.1 0.1 0.1 -0.0 0.4 -0.6 0.4 0.0 -0.1 0.2 0.3 0.1 0.1 -0.1 -0.0 -0.1 0.1 0.0 0.1 0.0 0.2 0.0 -0.5 0.0 0.0 0.1 0.1 -0.0 0.1 0.0 0.0 0.2
Knee pain experienced in last month 0.4 0.7 22.1 0.3 0.7 0.4 0.7 0.5 -0.3 0.2 0.3 0.2 0.4 0.3 4.7 0.3 -0.4 0.2 0.8 0.6 0.4 -0.8 0.6 0.3 0.8 1.1 0.9 1.0 0.4 0.3 0.5 0.3 -0.3 0.3 0.2 0.5 -0.6 0.4 0.3 0.3 0.4 0.4 -0.6 0.2 -0.2 0.3 0.4 0.5 -0.1 0.9 0.4 0.2 0.5 -0.3
Hypertension (Self-reported) 0.7 1.9 3.7 1.3 1.2 1.7 1.7 1.4 -1.1 1.0 1.3 1.5 1.3 1.3 1.9 1.4 1.7 1.2 1.5 0.4 1.4 1.8 1.4 1.4 1.5 1.6 1.0 1.2 1.2 1.3 1.5 1.5 1.4 1.3 1.6 1.4 -1.2 1.3 1.3 1.3 1.3 1.4 1.5 1.5 1.2 1.3 1.4 0.9 1.3 1.3 1.3 1.4 1.3 1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.7 0.8 4.0 -1.0 -1.0 -0.4 0.3 -1.0 0.5 -0.7 -0.9 -0.8 -0.9 -0.9 2.0 -0.7 0.9 -0.6 -0.4 -1.1 -0.8 -1.0 -0.5 -0.9 -0.4 -1.4 -0.6 -1.3 0.3 -0.9 -1.2 -1.0 -1.0 -1.0 -0.8 -1.1 0.9 -0.8 -1.0 -0.9 -0.9 -0.8 -0.7 -0.8 -0.6 -0.9 -0.8 -1.0 -0.9 -0.4 -0.9 -0.9 -0.9 -0.9
Illnesses of father: Heart disease 0.1 0.1 1.7 0.0 -0.0 -0.0 0.3 0.1 0.2 0.2 0.0 -0.1 0.1 -0.0 1.3 0.1 -0.1 -0.0 -1.0 -0.4 0.0 0.3 0.2 0.1 0.1 1.3 0.3 0.4 -0.5 0.0 -0.0 -0.0 -0.1 0.1 -0.1 0.2 -0.1 0.1 0.1 0.0 0.1 0.0 -0.2 0.0 -0.1 0.0 0.0 -0.0 0.2 0.4 0.1 0.0 0.1 0.2
Illnesses of siblings: Diabetes 0.2 0.2 1.7 -0.1 0.4 -0.1 0.1 -0.2 0.3 0.1 -0.3 -0.6 -0.2 -0.4 -1.3 -0.2 -0.7 -0.2 -1.3 0.2 -0.2 0.1 -0.5 -0.2 -0.4 -0.5 -0.6 -0.8 0.4 -0.3 -0.2 -0.5 -0.3 -0.1 -0.5 -0.3 -0.0 -0.2 -0.2 -0.2 -0.2 -0.2 -0.8 -0.3 -0.5 -0.3 -0.3 0.1 -0.4 -0.5 -0.2 -0.3 -0.2 -0.3
Smoking status: Previous 0.1 0.1 2.0 0.0 -0.1 0.2 -0.1 -0.1 -0.2 0.2 -0.0 0.3 0.1 0.2 0.8 0.0 0.5 -0.0 1.4 -0.5 0.1 0.0 -0.2 0.1 0.3 0.0 0.5 0.1 -0.3 -0.0 -0.2 0.1 0.4 0.1 0.2 0.0 0.1 -0.1 -0.0 -0.0 0.0 0.0 0.7 0.1 0.7 -0.0 0.1 -0.3 -0.1 -0.2 -0.1 0.1 -0.0 -0.2
Forced expiratory volume in 1-second (FEV1), predicted 0.1 0.3 1.7 0.5 0.3 -0.3 -0.1 0.5 -0.3 0.5 0.4 0.5 0.5 0.4 -0.7 0.6 1.3 0.4 0.5 0.7 0.3 -0.9 0.6 0.3 0.4 1.2 0.6 0.9 -0.5 0.4 0.5 0.4 -0.1 0.4 0.4 0.6 -0.4 0.5 0.5 0.4 0.5 0.5 0.1 0.5 -0.1 0.4 0.5 0.2 0.6 1.2 0.5 0.4 0.5 0.4
Whole body fat-free mass 0.4 2.0 9.1 1.4 1.6 1.4 2.1 1.3 -1.5 1.1 1.3 0.8 1.4 1.3 1.8 1.3 1.7 1.4 0.6 1.1 1.2 -0.8 1.4 1.3 1.3 0.8 1.9 1.1 1.3 1.3 1.2 1.0 0.3 1.3 0.9 1.3 -1.4 1.4 1.6 1.3 1.4 1.3 0.8 1.4 0.8 1.3 1.2 0.4 2.7 3.0 1.3 1.2 1.3 2.4
Leg fat-free mass (right) 0.2 1.1 6.0 1.0 1.0 0.8 1.6 0.8 -1.2 0.7 0.9 0.5 1.0 0.9 2.0 1.0 1.1 1.1 0.5 0.7 0.8 -1.1 1.0 1.0 1.1 0.5 1.5 1.2 1.0 0.9 0.6 0.5 -0.2 0.9 0.6 1.0 -1.1 1.1 1.2 1.0 1.0 0.9 0.2 1.0 0.4 0.9 0.9 0.4 1.9 2.4 1.0 0.8 1.0 1.7
Arm fat percentage (left) 0.1 0.2 2.1 0.2 0.1 0.1 1.1 -0.1 -0.6 -0.1 0.1 -0.2 0.1 0.1 1.5 0.1 0.0 0.5 -0.3 -0.8 -0.1 -1.0 0.1 0.2 0.3 -0.8 0.5 0.8 0.5 0.1 -0.2 -0.2 -0.6 0.2 -0.1 0.1 -0.1 0.2 0.4 0.1 0.2 0.1 -0.7 0.0 -0.2 0.1 0.0 0.1 0.7 0.7 0.2 -0.0 0.2 0.7
Average weekly red wine intake 13.7 20.2 31.6 -4.8 -5.1 -4.6 -5.0 -4.7 4.5 -4.8 -4.6 -5.0 -4.7 -4.7 -1.2 -4.7 -2.9 -4.2 -5.6 -4.0 -5.1 -3.4 -4.7 -4.7 -4.9 -3.9 -4.6 -4.6 -4.6 -4.6 -4.9 -5.1 -4.7 -4.6 -5.0 -4.9 4.8 -4.7 -4.6 -4.7 -4.6 -4.7 -2.9 -4.3 -3.3 -4.6 -4.7 -5.0 -3.0 -3.3 -4.8 -4.5 -4.8 -3.0
Handedness (chirality/laterality): Left-handed 1.5 1.9 5.4 1.4 1.6 1.2 0.1 1.6 -1.2 1.6 1.3 1.1 1.4 1.4 -1.1 1.4 1.6 1.2 1.1 2.0 1.3 1.4 1.4 1.4 1.1 2.3 0.9 1.1 0.9 1.4 1.6 1.4 0.8 1.3 1.2 1.4 -1.4 1.4 1.4 1.4 1.4 1.4 0.8 1.3 0.5 1.3 1.4 1.3 1.4 1.8 1.5 1.3 1.4 1.3
Mood swings 0.2 0.4 1.7 -0.4 -1.1 -0.5 -1.0 -0.6 -0.0 -0.6 -0.4 -0.8 -0.5 -0.4 -0.4 -0.3 -0.5 -0.6 0.5 -1.0 -0.6 -1.3 -0.5 -0.6 -0.4 -0.3 -0.6 -0.6 0.1 -0.4 -0.8 -0.8 -1.0 -0.5 -0.7 -0.3 0.5 -0.4 -0.6 -0.4 -0.5 -0.4 -0.7 -0.6 -0.5 -0.4 -0.4 -0.0 -1.0 -0.4 -0.4 -0.5 -0.4 -1.0
Loneliness, isolation 0.2 0.3 1.3 -0.4 -0.6 -0.1 -0.9 -0.4 0.2 -0.6 -0.4 -0.7 -0.5 -0.5 0.2 -0.5 0.3 -0.6 1.0 -0.5 -0.3 -1.1 -0.3 -0.5 -0.4 -0.7 -0.3 -1.1 0.4 -0.4 -0.5 -0.6 -0.6 -0.4 -0.6 -0.3 0.3 -0.5 -0.5 -0.4 -0.4 -0.4 0.0 -0.4 0.0 -0.4 -0.4 -0.4 -0.7 -0.5 -0.5 -0.4 -0.4 -0.8
Long-standing illness, disability or infirmity 0.5 0.7 2.6 -0.6 -0.3 -0.7 -1.6 -0.6 0.4 -1.1 -0.7 -1.5 -0.6 -0.7 -1.2 -0.7 -0.4 -0.9 -0.6 -0.8 -0.9 -1.0 -0.5 -0.5 -1.4 -0.7 -0.5 -0.1 -0.4 -0.7 -0.9 -1.3 -1.4 -0.6 -1.4 -0.7 0.4 -0.7 -0.5 -0.7 -0.6 -0.7 -0.9 -0.8 -1.1 -0.7 -0.7 -0.1 -0.8 -1.1 -0.5 -0.7 -0.6 -0.6
Ever had bowel cancer screening 0.3 0.4 2.0 -0.4 -0.6 -0.4 0.3 -0.6 0.5 -0.7 -0.3 -0.9 -0.3 -0.4 0.1 -0.3 -1.4 -0.0 -1.4 -0.6 -0.7 -0.6 -0.7 -0.1 -0.4 -1.2 -0.5 -0.9 0.1 -0.3 -1.1 -1.0 -0.4 -0.4 -0.7 -0.3 0.4 -0.4 -0.5 -0.3 -0.3 -0.3 0.0 -0.3 0.2 -0.3 -0.2 -0.1 -1.0 -1.3 -0.3 -0.2 -0.3 -0.9
Diabetes diagnosed by doctor 0.2 0.3 2.6 0.2 0.3 0.5 -1.1 0.3 -0.7 -0.0 0.2 -0.3 0.2 0.2 1.1 0.2 1.6 -0.0 1.3 -0.8 0.1 0.5 0.3 0.1 0.4 0.2 0.3 -1.3 0.7 0.2 -0.0 -0.1 -0.2 0.2 -0.1 0.2 -0.1 0.2 0.1 0.2 0.2 0.2 1.0 0.4 1.1 0.2 0.3 -0.2 0.3 0.1 0.1 0.4 0.1 0.2
Ever had stillbirth, spontaneous miscarriage or termination 0.2 0.2 0.8 0.4 -0.3 0.8 0.2 0.5 -0.3 0.8 0.4 0.4 0.5 0.4 -0.4 0.1 0.7 0.5 -0.3 0.1 0.4 -0.3 0.3 0.4 0.3 0.4 0.7 0.2 0.9 0.4 0.1 0.3 0.6 0.3 0.3 0.4 -0.4 0.3 0.5 0.4 0.4 0.4 0.2 0.3 -0.6 0.4 0.4 0.7 0.3 0.1 0.5 0.4 0.5 0.5
Friendships satisfaction 0.1 0.2 1.9 -0.1 -0.2 -0.5 -0.9 -0.1 -0.1 -0.1 -0.1 -0.3 -0.1 -0.1 0.9 -0.3 0.7 -0.3 -0.5 -0.5 -0.2 -0.2 -0.1 0.1 -0.4 1.3 -0.2 -1.4 0.1 -0.1 -0.2 -0.3 -0.1 -0.0 -0.3 -0.3 0.2 -0.1 -0.1 -0.1 -0.0 -0.1 0.4 0.0 0.5 -0.1 -0.1 -0.2 0.0 -0.1 -0.2 -0.0 -0.1 -0.1
Qualifications: nursing, teaching 0.4 0.6 2.8 -0.8 -1.7 -0.1 -0.9 -0.7 0.6 -0.7 -0.7 -0.7 -0.8 -0.5 -0.0 -0.7 0.4 -0.5 -1.0 -1.5 -0.9 0.1 -0.5 -0.9 -1.0 -0.0 -0.9 -0.7 -0.4 -0.7 -0.8 -0.8 -0.7 -0.7 -0.8 -0.6 0.9 -0.7 -0.8 -0.7 -0.8 -0.7 0.1 -0.6 0.2 -0.7 -0.7 -1.0 -0.7 -0.7 -0.8 -0.6 -0.8 -0.6
Commuting to job workplace: Walk 1.2 1.3 5.1 -1.1 -1.2 -0.7 -1.8 -1.2 0.9 -1.4 -1.1 -1.0 -1.1 -1.1 -0.7 -1.2 -0.4 -1.6 -1.0 -1.9 -1.2 -0.6 -1.1 -1.0 -1.4 -1.2 -1.0 -2.2 -0.7 -1.1 -1.5 -1.2 -0.8 -1.0 -1.1 -1.3 1.1 -1.2 -1.0 -1.1 -1.1 -1.2 -0.5 -1.0 -1.0 -1.1 -1.2 -1.3 -0.2 -0.9 -1.1 -1.1 -1.2 -0.1
Eye problems/disorders: Cataract 1.0 1.2 2.4 -1.2 -0.8 -1.3 -0.6 -1.1 1.2 -1.3 -1.0 -1.2 -1.1 -1.1 -0.4 -1.0 -1.3 -1.1 -1.6 -0.4 -1.1 -0.5 -1.0 -0.9 -1.2 -1.1 -1.3 -1.3 -0.8 -1.1 -1.2 -1.2 -1.2 -1.1 -1.2 -0.9 1.1 -1.0 -1.2 -1.1 -1.1 -1.0 -1.1 -1.1 -0.8 -1.0 -1.0 -0.9 -1.2 -0.6 -1.1 -1.1 -1.1 -1.3
Mouth/teeth dental problems: Mouth ulcers 4.7 7.4 9.7 -2.8 -2.8 -2.6 -2.7 -3.0 3.0 -2.5 -2.8 -2.8 -2.9 -2.8 -1.1 -2.7 -1.8 -2.8 -0.9 -2.6 -2.7 -3.0 -2.8 -3.0 -3.0 -2.2 -2.8 -2.1 -2.4 -2.8 -2.9 -2.9 -3.1 -2.9 -2.9 -2.9 2.8 -2.8 -2.9 -2.8 -2.9 -2.8 -2.8 -2.9 -2.6 -2.8 -2.8 -2.3 -2.8 -2.3 -2.8 -2.9 -2.8 -2.8
Medication for cholesterol 0.2 0.2 3.0 0.4 -0.1 -0.1 0.2 0.3 -0.2 1.0 0.4 0.5 0.3 0.4 -1.7 0.2 -0.6 0.0 0.5 -0.2 0.4 1.2 0.2 0.4 0.0 0.0 0.6 -0.3 0.0 0.4 0.4 0.5 0.8 0.5 0.4 0.3 -0.2 0.2 0.4 0.4 0.4 0.3 0.5 0.3 0.9 0.3 0.3 0.4 0.3 -0.5 0.3 0.4 0.3 0.4
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.4 0.5 1.4 -0.6 -0.0 -0.6 -0.7 -0.6 0.7 -0.8 -0.8 -1.0 -0.5 -0.8 -0.5 -1.0 -0.3 -1.0 -0.4 -0.7 -0.6 -0.5 -0.3 -0.6 -0.9 -0.7 0.3 0.0 -0.6 -0.8 -0.4 -0.8 -0.8 -0.6 -1.0 -0.7 0.5 -0.9 -0.6 -0.8 -0.6 -0.7 -0.6 -0.8 -1.1 -0.9 -0.7 -0.3 -1.1 -1.2 -0.7 -0.7 -0.6 -1.0
Back pain experienced in last month 0.1 0.2 1.2 0.5 0.1 -0.0 1.1 0.6 -0.6 0.6 0.4 0.2 0.5 0.3 -0.2 0.4 -0.5 0.4 -0.6 0.4 0.2 0.4 0.2 0.5 0.4 0.5 0.6 0.9 0.1 0.3 0.4 0.2 0.3 0.5 0.1 0.5 -0.5 0.4 0.6 0.4 0.4 0.4 -0.4 0.3 -0.2 0.4 0.4 0.6 0.4 0.1 0.5 0.4 0.5 0.6
Mineral and other dietary supplements 1.2 1.6 5.2 -1.4 -0.9 -1.8 -1.3 -1.3 1.4 -1.3 -1.3 -0.9 -1.4 -1.4 -0.5 -1.1 -0.8 -1.5 0.5 -1.4 -1.0 -0.5 -1.1 -1.3 -0.9 -0.3 -1.8 -0.2 -2.3 -1.3 -1.1 -1.1 -1.0 -1.4 -1.0 -1.3 1.2 -1.2 -1.4 -1.3 -1.4 -1.3 -1.8 -1.4 -1.3 -1.3 -1.3 -1.1 -1.4 -1.0 -1.2 -1.4 -1.3 -1.3
Breast cancer (self-reported) 0.4 0.4 2.0 -0.7 0.2 -0.2 -0.7 -0.5 0.5 -0.5 -0.6 -0.9 -0.6 -0.5 0.4 -0.7 -0.7 -0.5 -0.6 -0.3 -0.7 -1.4 -0.9 -0.7 -0.4 -0.6 -0.6 -0.9 -0.3 -0.7 -0.6 -0.8 -0.7 -0.7 -0.8 -0.5 0.7 -0.6 -0.5 -0.6 -0.7 -0.7 -0.4 -0.5 -1.0 -0.6 -0.7 -1.0 0.3 0.3 -0.6 -0.6 -0.7 0.3
Asthma (self-reported) 0.2 0.4 6.8 -0.3 -0.3 0.1 -0.7 -0.4 0.1 -0.7 -0.2 -1.0 -0.2 -0.2 -2.6 -0.4 -0.1 -0.1 -0.7 -1.0 -0.6 -0.9 -0.0 -0.4 -1.0 -0.7 -0.2 -0.7 0.8 -0.3 -0.9 -1.0 -0.6 -0.2 -0.7 0.0 0.2 -0.2 -0.1 -0.2 -0.2 -0.3 -0.3 -0.2 -0.2 -0.2 -0.3 -0.5 0.4 0.2 -0.2 -0.2 -0.3 0.5
Osteoporosis (self-reported) 0.3 0.4 1.7 -0.7 0.1 -0.1 -1.1 -0.5 0.5 -0.5 -0.7 -0.8 -0.6 -0.7 0.1 -0.7 -0.1 -0.4 -1.1 -0.0 -0.5 -0.4 -0.4 -0.7 -0.8 -0.2 -0.6 -0.2 0.5 -0.7 -0.4 -0.7 -0.5 -0.7 -0.8 -0.6 0.5 -0.8 -0.7 -0.7 -0.7 -0.7 -0.5 -0.7 -1.0 -0.7 -0.7 -0.3 -0.9 -1.3 -0.6 -0.6 -0.7 -0.7
Osteoarthritis (self-reported) 1.2 1.5 3.5 -1.2 -1.6 -1.3 -0.3 -1.3 1.2 -1.1 -1.2 -1.3 -1.2 -1.2 0.0 -1.2 -1.0 -1.2 -1.0 -1.7 -1.2 -1.7 -0.6 -1.1 -0.9 -1.9 -0.6 -0.6 -0.9 -1.2 -1.6 -1.4 -1.9 -1.3 -1.3 -1.1 1.0 -1.1 -1.1 -1.2 -1.2 -1.2 -1.8 -1.3 -1.9 -1.2 -1.2 -0.8 -1.1 -0.4 -1.1 -1.3 -1.1 -1.1
Medication: Aspirin 0.3 0.3 1.9 0.5 0.5 0.7 0.8 0.7 -0.5 -0.3 0.5 0.0 0.6 0.4 0.3 0.4 1.3 0.2 0.6 0.4 0.3 0.9 0.2 0.7 0.5 0.6 0.8 0.1 0.3 0.5 0.7 0.3 0.1 0.5 0.1 0.6 -0.5 0.4 0.5 0.5 0.5 0.5 1.4 0.7 0.7 0.5 0.6 -0.0 0.9 0.7 0.4 0.7 0.5 0.8
Medication: Gliclazide 0.3 0.3 2.1 0.5 0.8 0.2 -0.5 0.6 -0.5 0.4 0.6 -0.4 0.5 0.5 -1.4 0.4 0.7 0.6 1.3 -0.1 0.2 0.7 0.3 0.3 0.1 0.1 0.3 -0.5 0.6 0.6 0.2 -0.2 -0.3 0.5 -0.2 0.7 -0.6 0.4 0.3 0.6 0.5 0.5 1.4 0.6 0.9 0.5 0.6 0.5 0.1 -0.1 0.4 0.7 0.5 0.2
Illnesses of father: None of the above (group 1) 0.9 1.2 5.3 1.0 1.0 0.8 0.3 1.2 -1.0 1.0 0.9 1.5 1.0 1.0 0.8 1.1 1.4 0.9 0.3 2.3 1.2 0.8 0.8 0.9 1.3 0.9 0.8 1.4 0.9 0.9 1.8 1.6 0.9 0.9 1.4 1.0 -0.9 1.1 0.8 0.9 0.9 1.0 0.8 1.0 1.0 0.9 1.0 0.4 0.8 1.8 0.9 0.9 1.0 0.5
Smoking status: Current 0.7 1.0 3.5 -1.0 -1.2 -1.0 -0.7 -0.7 1.0 -1.2 -1.0 -0.7 -1.0 -1.0 -1.9 -0.9 -0.9 -1.1 -1.4 0.2 -0.9 -0.2 -0.9 -1.2 -0.9 -1.4 -1.0 -1.3 -0.9 -1.0 -0.7 -0.7 -0.3 -1.0 -0.7 -0.9 0.9 -1.1 -1.1 -1.0 -1.0 -1.0 -0.8 -1.1 -1.2 -1.0 -1.0 -0.5 -1.4 -1.5 -1.0 -1.0 -1.0 -1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.4 2.6 -0.5 -0.2 -1.2 0.1 -0.2 0.9 0.6 -0.4 -0.5 -0.6 -0.4 -1.0 -0.4 -0.8 -0.5 0.1 0.0 -0.5 1.0 -0.9 -0.6 -0.4 0.2 -0.8 -0.7 -1.6 -0.4 0.2 -0.3 -0.8 -0.6 -0.5 -0.6 0.6 -0.3 -0.5 -0.4 -0.6 -0.4 -0.2 -0.3 -0.1 -0.4 -0.4 -1.0 0.2 0.9 -0.5 -0.4 -0.5 0.1
Whole body water mass 0.4 2.0 9.0 1.4 1.6 1.4 2.1 1.3 -1.5 1.1 1.3 0.8 1.4 1.3 1.8 1.3 1.7 1.3 0.6 1.2 1.2 -0.8 1.4 1.3 1.4 0.8 1.9 1.1 1.3 1.3 1.2 1.0 0.3 1.3 0.9 1.3 -1.4 1.4 1.6 1.3 1.4 1.3 0.8 1.4 0.9 1.3 1.2 0.4 2.7 3.0 1.3 1.2 1.3 2.3
Leg predicted mass (right) 0.2 0.9 5.4 0.9 0.9 0.7 1.5 0.7 -1.1 0.6 0.8 0.4 0.9 0.8 1.9 0.9 1.1 1.0 0.5 0.6 0.7 -1.2 0.9 0.9 0.9 0.4 1.4 1.2 0.9 0.8 0.6 0.4 -0.3 0.8 0.5 0.9 -1.0 1.0 1.1 0.8 0.9 0.8 0.1 0.9 0.3 0.8 0.8 0.3 1.8 2.3 0.9 0.7 0.9 1.5
Arm fat mass (left) 0.1 0.6 3.0 0.7 0.7 0.6 1.5 0.4 -1.0 0.4 0.6 0.2 0.6 0.5 1.7 0.6 0.4 0.9 -0.3 -0.2 0.4 -1.1 0.6 0.7 0.8 -0.2 1.1 1.1 0.8 0.5 0.3 0.2 -0.3 0.6 0.3 0.6 -0.6 0.7 0.9 0.6 0.7 0.5 -0.4 0.6 0.1 0.6 0.5 0.2 1.6 1.7 0.7 0.4 0.6 1.5
Number of self-reported non-cancer illnesses 0.8 1.3 3.9 -1.1 -1.4 -1.0 -1.1 -1.1 0.7 -1.4 -1.2 -1.4 -1.1 -1.3 0.9 -1.2 -0.6 -1.3 -1.1 -2.0 -1.4 -0.3 -0.9 -0.9 -1.3 -0.1 -0.9 -1.2 -0.6 -1.2 -1.3 -1.4 -1.4 -1.1 -1.4 -1.1 1.1 -1.2 -0.9 -1.2 -1.1 -1.3 -1.4 -1.2 -1.7 -1.2 -1.3 -1.1 -0.4 -0.9 -1.1 -1.2 -1.2 -0.2
Average weekly champagne plus white wine intake 0.2 0.2 2.7 0.1 0.5 0.2 -0.4 0.1 -0.1 0.4 0.2 0.4 0.2 0.2 1.1 0.3 -0.2 0.2 1.0 0.8 0.5 -0.5 0.6 0.1 0.4 0.4 0.0 1.6 0.5 0.2 0.4 0.4 -0.2 -0.0 0.4 0.1 -0.3 0.3 0.2 0.1 0.2 0.2 -0.8 0.0 -0.3 0.1 0.1 0.2 0.2 1.0 0.3 -0.0 0.3 -0.0
Miserableness 0.5 0.9 2.6 1.1 0.2 0.5 -0.2 0.8 -1.3 0.8 1.1 0.8 1.1 1.0 0.9 1.2 1.0 1.0 1.6 0.3 0.7 0.1 1.0 1.0 1.2 0.7 1.2 0.8 0.5 1.1 0.5 0.6 0.5 1.0 0.8 1.2 -1.0 1.1 1.0 1.1 1.1 1.1 0.6 1.0 0.7 1.0 1.1 1.3 0.6 0.8 1.1 1.0 1.1 0.5
Guilty feelings 0.1 0.2 0.9 0.3 0.5 0.5 0.0 0.4 -0.4 0.6 0.4 -0.3 0.4 0.4 1.0 0.4 0.2 0.2 0.1 0.2 0.0 -0.6 0.3 0.2 0.3 0.5 0.6 0.2 0.7 0.3 0.1 -0.2 -0.5 0.3 -0.1 0.5 -0.4 0.3 0.3 0.3 0.3 0.4 0.4 0.5 0.0 0.4 0.4 0.1 0.3 0.4 0.4 0.5 0.4 0.5
Wears glasses or contact lenses 2.7 3.1 6.2 -1.9 -1.8 -1.1 -1.2 -1.7 1.7 -2.4 -1.6 -2.5 -1.8 -1.6 2.0 -1.8 -1.0 -1.5 -2.4 -2.4 -2.2 -1.6 -1.5 -1.7 -2.0 -1.3 -2.0 -1.8 -0.5 -1.7 -1.8 -2.3 -2.1 -1.7 -2.2 -1.8 1.9 -1.8 -1.8 -1.7 -1.9 -1.8 -1.0 -1.6 -1.1 -1.6 -1.7 -1.6 -1.5 -2.1 -1.8 -1.6 -1.8 -1.2
Ever taken oral contraceptive pill 3.5 3.9 10.0 2.1 1.4 1.6 1.7 2.1 -2.3 1.9 2.1 2.0 2.0 2.0 0.1 2.1 2.6 1.6 2.9 1.4 1.7 1.0 2.3 1.8 1.8 1.8 2.3 1.9 1.1 2.1 1.8 1.9 1.1 2.0 1.9 2.0 -1.9 2.2 2.2 2.1 2.1 2.1 1.6 2.1 1.7 2.1 2.0 1.4 2.7 3.2 2.0 2.0 2.1 2.4
Hearing aid user 0.5 0.5 3.0 -0.8 -0.6 -0.4 0.3 -0.6 0.9 -0.5 -0.6 -0.9 -0.7 -0.7 1.7 -0.5 -0.6 -0.5 -0.8 -1.3 -0.7 -0.0 -0.9 -0.7 -0.5 -1.6 -0.7 -0.5 -0.3 -0.7 -0.6 -0.8 -1.0 -0.8 -0.8 -0.8 0.8 -0.7 -0.7 -0.7 -0.7 -0.7 -0.1 -0.6 -0.4 -0.6 -0.7 -1.0 -0.1 0.2 -0.7 -0.7 -0.7 -0.2
Mother’s age at death 0.1 0.1 1.4 -0.1 -1.2 0.0 1.1 -0.3 -0.1 0.1 -0.1 0.4 -0.1 -0.1 -0.2 -0.1 -0.9 0.4 -0.7 -0.2 -0.1 -0.5 0.2 -0.3 -0.1 -0.5 -0.1 0.3 -0.0 -0.1 -0.3 0.2 0.1 0.0 0.3 -0.3 0.2 -0.1 0.0 -0.1 0.0 -0.1 -0.8 -0.3 -0.3 -0.1 -0.2 0.4 -0.3 -0.7 0.0 -0.2 -0.1 -0.2
Financial situation satisfaction 1.8 2.2 5.8 -1.5 -1.7 -1.5 -1.9 -1.5 1.3 -1.3 -1.4 -1.7 -1.5 -1.4 0.7 -1.4 -0.5 -1.5 -0.2 -1.4 -1.9 -2.4 -1.6 -1.6 -1.2 -2.3 -1.5 -1.9 -1.4 -1.4 -1.9 -1.8 -1.8 -1.6 -1.6 -1.3 1.6 -1.4 -1.3 -1.4 -1.6 -1.5 -1.4 -1.3 -1.7 -1.4 -1.6 -1.8 -0.1 -0.2 -1.4 -1.5 -1.5 -0.0
Tinnitus: Yes, now most or all of the time 3.0 3.6 10.4 -2.0 -1.9 -1.9 -2.1 -2.1 1.8 -2.2 -1.8 -2.1 -2.0 -1.8 2.2 -1.7 -0.6 -1.6 -1.9 -1.6 -2.0 -3.2 -1.9 -1.9 -1.8 -1.0 -2.2 -2.0 -1.4 -1.9 -2.3 -2.2 -2.5 -2.1 -2.1 -1.7 1.9 -1.7 -2.0 -1.9 -2.0 -1.9 -1.4 -1.8 -0.9 -1.8 -1.9 -2.2 -1.3 -0.5 -2.0 -1.9 -1.9 -1.6
Commuting to job workplace: Public transport 0.5 0.6 2.5 0.8 0.1 1.1 -0.7 0.6 -1.1 0.3 0.8 0.8 0.8 0.9 -1.5 0.7 0.8 0.2 0.2 0.9 0.7 -0.8 0.6 1.0 0.6 0.8 0.5 -0.2 1.6 0.8 0.4 0.7 0.8 0.9 0.8 0.7 -0.7 0.7 0.9 0.8 0.8 0.7 0.6 0.8 0.5 0.8 0.7 0.7 0.9 0.3 0.8 0.8 0.8 1.1
Eye problems/disorders: Glaucoma 2.1 2.5 5.6 -1.8 -1.4 -1.3 -0.9 -1.8 1.5 -1.5 -1.8 -1.6 -1.7 -1.6 -0.8 -1.7 -0.8 -1.6 -1.7 -1.7 -1.4 -2.3 -1.8 -1.7 -1.6 -1.7 -1.3 -0.6 -0.8 -1.8 -1.6 -1.6 -1.9 -1.9 -1.6 -1.8 1.8 -1.7 -1.8 -1.8 -1.7 -1.7 -0.8 -1.6 -1.0 -1.8 -1.7 -2.4 -0.9 0.2 -1.9 -1.8 -1.8 -1.4
Medication: Blood pressure 0.6 1.1 3.4 1.0 1.1 1.2 0.6 1.1 -1.2 0.9 1.0 1.3 1.1 1.0 1.4 1.1 0.3 1.1 0.2 1.0 1.2 0.5 1.3 1.1 1.6 1.8 0.7 1.2 0.6 1.0 1.1 1.2 1.1 1.0 1.3 1.1 -1.1 1.0 0.9 1.0 1.0 1.1 0.6 1.0 0.3 1.0 1.1 1.1 0.5 0.8 1.1 1.0 1.1 0.4
Pain type(s) experienced in last month: Hip pain 0.4 0.6 2.3 0.7 1.4 0.7 0.9 0.8 -0.7 0.6 0.7 0.5 0.7 0.8 -0.3 0.7 0.0 0.9 0.3 1.4 0.8 1.5 0.6 0.7 0.6 0.3 0.4 1.1 -0.0 0.7 1.2 0.7 0.8 0.7 0.5 0.6 -0.8 0.7 0.8 0.7 0.7 0.6 0.4 0.6 0.4 0.7 0.6 0.8 0.7 0.3 0.7 0.7 0.7 0.8
Supplements: Fish oil (including cod liver oil) 0.8 1.1 3.7 1.1 0.4 1.4 1.5 1.1 -0.8 1.0 0.9 0.8 1.1 1.0 0.1 0.8 1.0 1.1 0.3 1.2 0.9 1.0 0.8 0.9 0.8 0.3 1.9 0.1 1.4 0.9 0.9 1.0 0.8 1.0 0.8 1.1 -0.9 0.9 1.0 1.0 1.1 1.0 1.9 1.2 1.4 0.9 1.1 0.3 1.2 1.3 0.8 1.1 0.9 0.9
High cholesterol (Self-reported) 0.2 0.3 1.8 -0.5 -0.8 -0.2 -1.2 -0.5 0.3 -1.0 -0.4 -0.7 -0.5 -0.5 1.0 -0.3 1.4 -0.6 -0.5 -1.1 -0.6 0.3 -0.4 -0.4 -0.3 0.0 -0.8 -0.7 -0.3 -0.4 -0.9 -0.8 -0.6 -0.5 -0.6 -0.4 0.5 -0.4 -0.5 -0.4 -0.5 -0.4 -0.0 -0.3 -0.4 -0.4 -0.4 -0.6 -0.1 -0.2 -0.4 -0.4 -0.5 0.0
Medication: Bendroflumethiazide 0.2 0.3 1.8 -0.5 -0.7 0.0 0.2 -0.5 0.5 -0.3 -0.6 0.1 -0.5 -0.7 1.3 -0.6 -0.4 -0.5 -1.2 -0.5 -0.3 -0.4 -0.2 -0.4 -0.3 -0.2 -0.5 0.2 -0.1 -0.6 -0.3 -0.0 -0.1 -0.5 -0.0 -0.6 0.6 -0.5 -0.5 -0.6 -0.5 -0.5 -0.7 -0.6 -0.9 -0.6 -0.6 -0.5 -0.3 0.2 -0.5 -0.6 -0.5 -0.5
Medication: Paracetamol 1.6 2.4 5.6 -1.4 -1.2 -0.9 -1.2 -1.5 1.2 -1.5 -1.6 -1.8 -1.4 -1.8 0.1 -1.7 -1.3 -1.5 -2.4 -0.7 -1.5 -2.0 -1.6 -1.5 -1.6 -1.9 -0.7 -1.1 -0.6 -1.6 -1.7 -1.8 -1.5 -1.5 -1.9 -1.5 1.3 -1.7 -1.5 -1.6 -1.5 -1.6 -1.8 -1.8 -2.0 -1.7 -1.6 -0.7 -2.1 -2.3 -1.5 -1.6 -1.5 -1.9
Medication: Lisinopril 0.1 0.2 4.1 0.3 -0.1 0.3 0.2 0.3 -0.5 0.5 0.4 -0.3 0.4 0.4 2.0 0.3 -0.1 0.2 -0.3 -0.3 -0.1 -0.0 0.3 0.2 0.3 0.5 0.3 -0.2 0.1 0.4 -0.0 -0.2 0.0 0.3 -0.1 0.3 -0.2 0.3 0.3 0.4 0.4 0.4 0.7 0.4 0.4 0.4 0.4 0.4 0.2 -0.1 0.3 0.4 0.3 0.2
Medication: Atorvastatin 1.2 1.5 4.2 1.2 1.1 1.3 0.4 1.5 -1.2 0.5 1.2 0.9 1.1 1.1 1.1 1.1 1.7 0.9 1.2 1.5 1.0 1.4 1.2 1.3 1.3 2.1 0.8 1.7 1.2 1.2 1.7 1.3 1.5 1.2 1.0 1.3 -1.1 1.0 1.2 1.2 1.2 1.1 1.5 1.2 0.8 1.2 1.1 1.4 0.9 -0.0 1.2 1.3 1.1 1.2
Illnesses of father: High blood pressure 0.2 0.2 2.1 -0.3 -0.4 -0.7 0.3 -0.4 0.2 -0.7 -0.3 -0.1 -0.3 -0.3 -0.5 -0.3 -0.6 -0.1 0.7 -1.1 -0.4 0.2 -0.2 -0.1 -0.4 -0.1 -0.5 -1.1 -1.2 -0.3 -0.6 -0.3 0.1 -0.1 -0.2 -0.3 0.3 -0.4 -0.2 -0.3 -0.3 -0.4 -0.1 -0.3 -0.0 -0.3 -0.4 0.0 -0.3 -1.4 -0.3 -0.2 -0.4 0.0
Alcohol drinker status: Never 1.7 2.0 3.6 1.3 0.9 1.8 1.7 1.4 -0.9 1.6 1.6 1.5 1.3 1.6 1.6 1.5 -0.2 1.5 1.9 1.9 1.4 1.3 1.4 1.1 1.7 1.3 0.8 1.6 1.8 1.5 1.2 1.3 1.3 1.2 1.6 1.8 -1.4 1.6 1.2 1.5 1.3 1.5 1.0 1.3 0.8 1.6 1.5 1.9 0.6 0.7 1.6 1.4 1.5 0.8
Ever smoked 0.1 0.2 1.7 0.2 -0.2 0.4 0.2 0.2 -0.4 0.2 0.2 0.5 0.2 0.3 -0.4 0.2 0.6 -0.0 0.7 0.3 0.2 0.5 0.0 0.1 0.4 -0.0 0.5 -1.0 -0.3 0.2 0.3 0.4 0.9 0.3 0.4 0.1 -0.0 0.1 0.1 0.2 0.2 0.2 1.2 0.4 1.3 0.2 0.3 -0.1 -0.2 -0.5 0.0 0.4 0.1 -0.2
Basal metabolic rate 0.4 2.1 9.0 1.4 1.6 1.4 2.1 1.3 -1.6 1.1 1.3 0.8 1.4 1.3 1.9 1.4 1.6 1.4 0.6 1.1 1.2 -0.9 1.4 1.4 1.4 0.8 2.0 1.3 1.4 1.3 1.2 1.0 0.3 1.4 1.0 1.3 -1.4 1.5 1.7 1.4 1.5 1.3 0.7 1.5 0.9 1.3 1.2 0.5 2.7 3.0 1.4 1.2 1.4 2.4
Leg fat percentage (left) 0.1 0.4 2.9 0.6 0.9 0.3 1.3 0.5 -0.8 0.4 0.5 0.3 0.5 0.5 1.7 0.5 0.3 0.7 0.3 0.2 0.4 -0.2 0.5 0.5 0.7 -0.5 1.0 1.0 0.4 0.5 0.6 0.5 -0.2 0.5 0.3 0.5 -0.5 0.6 0.7 0.5 0.6 0.5 0.1 0.5 0.6 0.5 0.4 0.2 1.1 1.4 0.5 0.4 0.5 1.0
Arm fat-free mass (left) 0.5 2.4 11.0 1.5 1.7 1.6 2.4 1.5 -1.5 1.3 1.4 1.0 1.5 1.4 2.2 1.4 1.4 1.3 0.6 1.2 1.3 -0.7 1.5 1.4 1.5 1.0 2.2 1.3 1.4 1.4 1.5 1.2 0.4 1.4 1.1 1.4 -1.5 1.5 1.7 1.4 1.5 1.4 0.9 1.6 0.9 1.4 1.3 0.4 2.9 3.3 1.4 1.3 1.4 2.5
Number of operations (self-reported) 0.3 0.4 4.2 -0.0 0.1 0.0 0.1 0.3 -0.2 0.1 0.0 -0.5 0.1 -0.1 -0.5 0.2 -0.8 0.5 -1.0 0.5 -0.1 -1.8 0.4 0.1 0.1 -0.4 0.1 2.0 0.3 -0.0 0.1 -0.3 -1.1 -0.2 -0.4 0.3 -0.2 0.2 0.2 0.0 0.0 0.1 -1.6 -0.2 -1.7 0.0 -0.1 0.4 0.3 1.0 0.3 -0.2 0.2 0.4
Average weekly beer plus cider intake 2.7 3.8 7.8 2.1 2.8 1.5 1.1 2.3 -2.3 1.9 2.0 2.1 2.2 2.1 0.5 2.1 1.4 1.9 1.8 1.6 2.2 1.5 1.5 2.0 2.2 2.0 2.0 1.7 0.9 2.0 2.5 2.3 2.3 2.1 2.1 2.2 -2.1 2.0 2.2 2.1 2.1 2.0 1.5 2.0 1.2 2.0 2.0 2.3 1.8 0.9 2.1 2.0 2.1 2.0
Irritability 3.4 5.7 13.3 -2.3 -3.0 -2.6 -2.1 -2.4 1.9 -2.3 -2.4 -2.5 -2.3 -2.4 0.7 -2.5 -1.7 -2.5 -0.8 -3.6 -2.6 -1.7 -2.5 -2.5 -2.3 -2.7 -2.2 -2.9 -2.4 -2.4 -2.9 -2.7 -2.2 -2.2 -2.6 -2.5 2.4 -2.5 -2.3 -2.4 -2.4 -2.4 -2.1 -2.5 -2.5 -2.4 -2.4 -1.8 -2.2 -2.6 -2.3 -2.4 -2.4 -2.0
Risk taking 0.2 0.3 3.3 -0.4 -0.9 -0.5 0.5 -0.2 0.5 -0.1 -0.5 -0.5 -0.3 -0.3 -1.3 -0.4 -0.3 -0.5 -0.8 -0.7 -0.5 0.1 -0.3 -0.2 -0.4 -0.5 0.0 -1.8 -0.6 -0.5 -0.3 -0.4 -0.0 -0.2 -0.5 -0.5 0.3 -0.5 -0.4 -0.5 -0.5 -0.4 0.3 -0.2 0.5 -0.5 -0.4 -1.2 -0.0 0.1 -0.6 -0.3 -0.5 -0.2
Ever had prostate specific antigen (PSA) test 0.2 0.3 2.6 0.4 -0.1 0.6 1.3 0.3 -0.4 0.4 0.3 -0.1 0.4 0.3 1.6 0.3 -0.5 0.8 -1.4 -0.2 0.0 -0.2 -0.0 0.4 0.1 -0.4 0.4 0.5 1.3 0.3 0.2 -0.0 -0.2 0.3 0.0 0.1 -0.4 0.3 0.4 0.3 0.4 0.3 0.2 0.3 0.1 0.3 0.3 0.5 0.4 -0.1 0.4 0.3 0.3 0.5
Fractured/broken bones in last 5 years 0.7 1.0 2.8 -0.9 -0.6 -1.2 -1.0 -0.9 0.9 -1.2 -0.9 -0.9 -0.9 -0.9 -1.7 -0.7 -1.4 -0.7 -0.1 -1.2 -0.9 -0.7 -1.2 -1.0 -0.9 -1.3 -0.9 -0.6 -1.6 -0.9 -1.0 -1.0 -0.9 -0.9 -0.9 -0.8 0.9 -0.9 -0.9 -0.9 -1.0 -0.9 -0.9 -1.0 -1.3 -0.8 -0.9 -0.4 -1.1 -1.3 -0.8 -0.9 -0.8 -0.9
Age started oral contraceptive pill 0.3 0.4 1.8 -0.6 0.1 -0.4 -0.4 -0.6 0.7 -0.7 -0.5 -0.6 -0.7 -0.6 0.6 -0.4 -0.4 -0.5 -0.8 -0.1 -0.5 1.0 -0.8 -0.6 -0.1 -0.3 -1.1 -1.4 -0.7 -0.5 -0.6 -0.6 -0.4 -0.6 -0.6 -0.7 0.6 -0.6 -0.8 -0.6 -0.7 -0.5 0.0 -0.5 -0.0 -0.5 -0.5 -0.3 -1.2 -1.2 -0.7 -0.5 -0.6 -1.1
Diastolic blood pressure, automated reading 0.2 0.6 3.5 0.6 0.0 0.8 1.7 0.3 -0.7 0.6 0.5 1.1 0.5 0.5 0.8 0.7 1.0 0.7 0.5 -0.4 0.8 -0.7 1.3 0.6 0.7 -0.4 0.8 0.7 1.3 0.5 0.3 1.0 0.5 0.5 1.1 0.5 -0.5 0.7 0.7 0.5 0.6 0.6 -0.6 0.4 0.3 0.5 0.5 0.3 0.8 1.9 0.6 0.3 0.6 0.4
Ever depressed for a whole week 0.4 0.4 3.1 0.5 1.8 0.2 0.1 0.9 -0.5 0.6 0.5 0.4 0.7 0.4 0.5 0.4 0.2 1.0 0.4 0.8 0.8 1.6 0.4 0.5 0.4 0.8 0.5 1.0 -0.5 0.5 1.2 0.7 0.5 0.6 0.3 0.5 -0.8 0.3 0.6 0.5 0.5 0.4 0.5 0.5 -0.4 0.4 0.5 0.6 0.7 -0.1 0.6 0.6 0.5 1.0
Unable to work because of sickness or disability 0.9 1.2 2.4 -1.2 -1.2 -0.9 -1.2 -1.0 1.2 -1.0 -1.1 -1.4 -1.1 -1.1 -1.3 -1.0 -0.6 -1.1 -0.9 -0.9 -1.4 -0.8 -0.9 -1.3 -1.6 -1.1 -1.3 -0.7 -0.6 -1.2 -0.8 -1.3 -1.2 -1.1 -1.4 -0.8 1.0 -1.1 -1.1 -1.1 -1.1 -1.1 -0.7 -1.0 -1.1 -1.1 -1.1 -1.1 -0.8 -0.7 -1.1 -1.1 -1.1 -0.7
Commuting to job workplace: Cycle 2.6 3.2 6.6 -1.8 -2.0 -1.6 -2.2 -1.9 1.6 -2.0 -1.9 -1.6 -1.8 -1.7 -1.5 -1.9 -2.6 -2.1 -0.9 -1.8 -1.6 -1.8 -1.4 -1.7 -1.7 -1.7 -2.1 -1.9 -1.6 -1.9 -2.1 -1.8 -1.4 -1.8 -1.7 -1.9 1.7 -1.9 -1.8 -1.8 -1.8 -1.8 -1.4 -1.8 -1.5 -1.9 -1.8 -1.7 -1.6 -1.4 -1.8 -1.8 -1.8 -1.6
Myopia 0.5 0.7 2.3 -0.7 -1.3 -1.2 -1.2 -0.8 0.7 -0.9 -0.7 -1.0 -0.8 -0.8 -0.5 -0.8 -0.7 -0.8 -0.1 -0.7 -1.0 -0.5 -0.6 -0.7 -1.0 -1.5 -1.0 -0.9 -1.3 -0.7 -0.9 -1.1 -0.9 -0.7 -1.0 -0.7 0.8 -0.8 -0.7 -0.7 -0.7 -0.8 -0.5 -0.8 -0.3 -0.7 -0.8 -0.6 -0.6 -0.8 -0.8 -0.8 -0.8 -0.6
Vascular/heart problems diagnosed by doctor 1.0 2.7 5.9 -1.6 -1.5 -2.1 -1.4 -1.8 1.5 -1.0 -1.6 -1.7 -1.7 -1.5 -1.8 -1.6 -1.9 -1.5 -1.2 -0.6 -1.6 -2.4 -1.5 -1.7 -1.6 -2.2 -1.4 -0.9 -1.4 -1.6 -1.8 -1.7 -1.8 -1.6 -1.7 -1.7 1.5 -1.5 -1.6 -1.6 -1.6 -1.6 -2.3 -1.9 -1.4 -1.6 -1.7 -1.1 -1.9 -1.4 -1.6 -1.8 -1.6 -1.9
Cholesterol lowering medication 1.6 2.3 5.0 -1.6 -1.0 -0.9 -2.0 -1.5 1.5 -2.0 -1.6 -2.1 -1.6 -1.7 0.2 -1.4 -0.4 -1.5 -2.2 -0.9 -1.7 -1.4 -1.6 -1.5 -1.6 -0.8 -1.7 -1.1 -0.9 -1.6 -1.6 -2.0 -1.9 -1.7 -2.0 -1.5 1.5 -1.5 -1.6 -1.6 -1.6 -1.6 -1.2 -1.5 -1.7 -1.6 -1.6 -1.8 -0.9 -0.5 -1.6 -1.6 -1.6 -1.0
Medication: Omeprazole (e.g. Zanprol) 5.5 6.7 10.5 -2.7 -3.0 -2.5 -2.0 -2.8 2.5 -2.6 -2.8 -2.7 -2.7 -2.8 -0.8 -2.6 -1.9 -2.8 -2.9 -1.6 -2.9 -3.1 -2.7 -2.5 -2.8 -2.1 -2.4 -1.5 -1.8 -2.8 -2.8 -2.9 -2.5 -2.7 -2.7 -2.7 2.7 -2.6 -2.8 -2.7 -2.7 -2.6 -2.6 -2.8 -2.0 -2.7 -2.6 -2.2 -3.1 -2.5 -2.7 -2.7 -2.6 -3.2
Pain experienced in last month 0.1 0.2 1.2 0.1 -0.6 0.2 -0.3 -0.2 -0.2 0.2 0.1 0.5 0.0 0.1 -0.8 0.0 0.8 -0.1 0.3 -0.6 0.1 -0.1 0.3 0.3 -0.1 -0.9 -0.2 -1.1 0.4 0.1 -0.5 0.3 0.5 0.1 0.4 -0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.7 0.2 0.9 0.1 0.1 -0.4 0.5 0.6 -0.1 0.1 -0.0 0.2
Supplements: Calcium 0.4 0.4 0.9 0.7 0.4 0.7 0.5 0.7 -0.5 0.7 0.6 0.2 0.7 0.6 0.7 0.5 -0.0 0.9 -0.9 0.8 0.3 0.7 0.4 0.7 0.4 0.2 0.5 0.7 0.9 0.7 0.5 0.3 0.3 0.7 0.2 0.6 -0.6 0.6 0.7 0.7 0.7 0.6 1.0 0.7 0.5 0.6 0.7 0.6 0.7 0.3 0.7 0.7 0.6 0.7
Basal cell carcinoma (self-reported) 0.2 0.3 2.6 -0.5 -0.3 -0.4 -0.4 -0.1 0.6 -0.3 -0.2 -0.6 -0.4 -0.2 -0.1 -0.3 -0.1 -0.0 -0.1 0.5 -0.2 0.4 -0.4 -0.5 -0.4 -0.4 -0.9 0.6 -0.2 -0.3 0.1 -0.4 -0.7 -0.5 -0.6 -0.2 0.1 -0.3 -0.7 -0.3 -0.5 -0.2 -0.2 -0.4 -0.4 -0.2 -0.2 0.2 -1.6 -1.0 -0.3 -0.3 -0.2 -1.5
Heart attack/myocardial infarction (self-reported) 1.6 2.0 7.1 1.5 0.8 2.2 0.6 1.4 -1.4 1.3 1.6 1.0 1.5 1.4 -0.3 1.5 0.5 1.4 0.8 0.3 1.1 2.7 0.9 1.5 1.6 1.4 1.2 0.2 1.6 1.6 0.9 0.9 1.7 1.6 1.1 1.6 -1.4 1.3 1.6 1.5 1.6 1.4 2.1 1.6 1.3 1.5 1.5 1.4 1.6 0.4 1.5 1.7 1.4 1.9
Deep venous thrombosis (DVT) (self-reported) 1.1 1.5 4.6 -1.1 -0.7 -1.1 -0.8 -1.2 1.3 -2.0 -1.2 -1.7 -1.2 -1.3 0.9 -1.1 -0.1 -1.2 -2.1 -1.1 -1.2 -0.3 -1.5 -1.1 -1.1 -1.8 -1.2 -1.0 -1.0 -1.1 -1.2 -1.6 -1.3 -1.1 -1.7 -1.3 0.9 -1.2 -1.2 -1.2 -1.1 -1.2 -0.5 -1.1 -0.3 -1.2 -1.2 -1.2 -1.0 -1.0 -1.3 -1.1 -1.2 -1.3
Heart disease (siblings) 0.3 0.4 1.2 0.7 0.1 0.9 0.8 0.5 -0.9 0.2 0.5 0.9 0.6 0.5 -0.5 0.5 1.1 0.5 -0.4 0.5 0.7 -0.2 0.4 0.9 0.6 0.0 0.3 -0.1 1.0 0.6 0.7 0.9 0.8 0.8 0.7 0.5 -0.6 0.6 0.7 0.6 0.7 0.6 0.2 0.5 0.5 0.5 0.6 0.6 0.5 0.8 0.6 0.5 0.6 0.2
Alcohol drinker status: Previous 0.3 0.4 2.0 0.7 0.6 0.9 -0.4 0.6 -0.6 0.4 0.6 0.6 0.6 0.6 0.5 0.7 1.4 0.8 -0.1 0.5 0.8 0.4 0.5 0.7 0.7 -0.1 0.6 0.0 0.7 0.6 0.5 0.6 0.8 0.7 0.6 0.6 -0.7 0.6 0.7 0.6 0.7 0.6 0.6 0.6 0.6 0.6 0.6 0.6 0.6 0.2 0.6 0.6 0.6 0.6
Pack years of smoking 0.9 1.3 2.6 -1.3 -0.2 -0.7 -0.0 -1.1 1.2 -1.3 -1.3 -1.0 -1.4 -1.5 -0.2 -1.2 -1.3 -0.8 -1.6 -0.7 -0.9 -0.9 -1.0 -1.4 -1.3 -1.2 -0.9 -0.7 -0.2 -1.3 -0.8 -0.9 -1.1 -1.4 -1.2 -1.4 1.2 -1.3 -1.4 -1.3 -1.3 -1.3 -0.9 -1.3 -0.6 -1.3 -1.3 -1.4 -1.3 -0.5 -1.4 -1.3 -1.3 -1.6
Impedance of whole body 0.3 1.5 10.2 -1.0 -1.5 -0.9 -2.1 -1.1 0.9 -0.9 -1.0 -0.6 -1.0 -1.0 -2.4 -1.1 -0.8 -0.9 -0.4 -1.6 -1.0 0.3 -1.1 -0.9 -1.2 -0.9 -1.4 -1.4 -0.7 -1.0 -1.3 -0.9 0.1 -0.9 -0.7 -1.2 1.1 -1.2 -1.2 -1.0 -1.0 -1.0 -0.7 -1.2 -0.5 -1.0 -0.9 0.0 -2.4 -3.2 -1.0 -0.9 -1.0 -2.0
Leg fat mass (left) 0.3 1.2 5.6 1.1 1.4 0.8 1.9 0.9 -1.3 0.8 1.0 0.6 1.0 0.9 1.8 1.0 1.0 1.1 0.3 0.5 0.8 -0.6 1.0 0.9 1.2 0.1 1.6 1.2 0.9 1.0 0.9 0.8 0.0 1.0 0.7 1.0 -0.9 1.1 1.2 1.0 1.0 0.9 0.3 1.0 0.7 0.9 0.9 0.4 2.0 2.4 1.0 0.8 1.0 1.7
Arm predicted mass (left) 0.5 2.5 10.8 1.6 1.6 1.7 2.5 1.4 -1.5 1.4 1.4 1.0 1.6 1.4 2.3 1.4 1.5 1.3 0.5 1.2 1.3 -0.8 1.4 1.4 1.6 0.9 2.2 1.3 1.5 1.4 1.4 1.2 0.4 1.5 1.1 1.4 -1.5 1.6 1.8 1.4 1.6 1.4 1.0 1.6 1.1 1.4 1.4 0.3 3.0 3.3 1.4 1.4 1.4 2.6