Hub : Genes

TAS2R5

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0990 0.0250 2.5e-13 0.116 0.113 0.142 0.110 0.141 5.6e-14 1.4e-13 6.8e-17 2.7e-13 7.8e-17
2 GTEx Brain Cerebellar Hemisphere 0.2170 0.1020 3.7e-03 0.065 NA 0.061 NA -0.012 9.3e-03 NA 1.2e-02 NA 9.6e-01
3 GTEx Breast Mammary Tissue 0.1170 0.0510 2.9e-03 0.010 NA 0.022 NA 0.001 9.4e-02 NA 2.6e-02 NA 2.6e-01
4 GTEx Breast Mammary Tissue (Male) 0.1657 0.1085 8.1e-02 -0.012 NA -0.006 NA -0.002 7.6e-01 NA 4.7e-01 NA 3.6e-01
5 GTEx Cells EBV-transformed lymphocytes 0.1710 0.0720 1.2e-03 0.058 NA 0.063 NA 0.089 6.0e-03 NA 4.1e-03 NA 7.7e-04
6 GTEx Esophagus Gastroesophageal Junction 0.1150 0.0530 3.6e-03 0.115 NA 0.007 NA 0.063 6.0e-05 NA 1.7e-01 NA 2.6e-03
7 GTEx Esophagus Mucosa 0.1630 0.0470 2.7e-08 0.149 NA 0.134 NA 0.120 3.7e-10 NA 3.2e-09 NA 2.3e-08
8 GTEx Esophagus Muscularis 0.0720 0.0300 2.0e-03 0.088 NA 0.058 NA 0.086 5.0e-06 NA 2.1e-04 NA 6.9e-06
9 GTEx Prostate 0.3000 0.0880 1.2e-04 0.079 NA 0.023 NA 0.044 5.2e-03 NA 8.7e-02 NA 3.0e-02
10 GTEx Skin Not Sun Exposed Suprapubic 0.1770 0.0610 3.3e-04 -0.004 NA 0.059 NA 0.005 6.4e-01 NA 3.6e-04 NA 1.5e-01
11 GTEx Skin Sun Exposed Lower leg 0.0860 0.0360 5.4e-04 0.049 NA 0.020 NA 0.029 6.6e-05 NA 7.9e-03 NA 1.6e-03
12 GTEx Spleen 0.1710 0.0750 3.8e-03 0.121 NA 0.007 NA 0.058 5.2e-04 NA 2.0e-01 NA 1.3e-02
13 GTEx Thyroid 0.1250 0.0400 4.0e-07 0.069 NA 0.024 NA 0.079 6.0e-06 NA 5.3e-03 NA 1.1e-06
14 GTEx Vagina 0.1790 0.0750 5.5e-03 -0.011 NA -0.012 NA -0.007 6.7e-01 NA 7.4e-01 NA 4.8e-01
15 ROSMAP Brain Pre-frontal Cortex 0.0556 0.0172 1.1e-07 0.059 0.066 0.065 0.064 0.070 4.4e-08 7.4e-09 9.2e-09 1.3e-08 2.6e-09
16 TCGA Breast Invasive Carcinoma 0.0207 0.0150 4.0e-04 0.012 0.012 0.010 NA 0.014 1.0e-03 1.6e-03 3.4e-03 NA 6.0e-04
17 TCGA Brain Lower Grade Glioma 0.0435 0.0313 7.6e-04 0.008 0.016 0.017 NA 0.010 3.7e-02 5.3e-03 4.7e-03 NA 2.3e-02
18 TCGA Lung Adenocarcinoma 0.0554 0.0330 3.7e-08 0.076 0.068 0.071 NA 0.050 3.0e-09 2.3e-08 1.1e-08 NA 1.5e-06
19 TCGA Lung Squamous Cell Carcinoma 0.0302 0.0268 1.1e-03 0.032 0.008 0.009 NA 0.024 1.4e-04 3.8e-02 3.2e-02 NA 8.3e-04
20 TCGA Prostate Adenocarcinoma 0.0399 0.0297 7.9e-05 0.044 0.018 0.018 NA 0.016 2.2e-05 4.8e-03 4.5e-03 NA 7.6e-03
21 TCGA Stomach Adenocarcinoma 0.0630 0.0470 3.6e-04 0.045 0.051 0.050 NA 0.042 3.2e-04 1.4e-04 1.7e-04 NA 4.8e-04
22 TCGA Thyroid Carcinoma 0.0570 0.0420 6.4e-05 0.052 0.042 0.039 NA 0.045 7.9e-06 5.7e-05 1.1e-04 NA 3.5e-05

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bipolar Disorder (2018) 0.2 0.2 1.6 -0.4 -0.6 -0.3 0.0 -0.0 -0.4 -0.5 0.2 0.3 0.0 -0.4 -0.4 -0.3 0.5 -0.3 -0.5 -1.2 -0.6 -0.4 -0.5 -0.7 -0.5
Bipolar Disorder or Schizophrenia 0.2 0.5 1.5 -0.7 -0.7 0.3 0.0 0.0 -0.8 -0.8 -0.4 0.4 -0.7 -0.7 -0.8 -0.7 0.5 -0.7 -0.7 -1.2 -0.8 -0.7 -1.0 -0.9 -0.8
Depressed Affect (Nagel 2018) 0.1 0.2 1.1 0.4 0.3 0.1 0.0 0.5 0.2 1.0 0.6 0.2 -1.1 0.3 0.3 0.5 1.0 0.5 0.1 -0.1 0.2 0.2 0.0 0.0 0.3
Depression (Nagel 2018) 0.8 1.2 8.7 -0.6 -0.7 -1.3 -2.3 0.3 -1.0 -0.3 -0.2 0.5 -3.0 -0.7 -0.9 -0.8 -0.8 -0.5 -0.9 -0.9 -0.9 -0.8 -0.9 -0.9 -0.8
Intelligence (Savage-Jansen 2018) 0.7 2.3 7.1 1.1 1.8 2.0 1.2 2.5 1.1 1.6 1.4 -2.7 -0.1 1.1 1.2 1.4 0.8 1.8 1.4 1.9 1.3 1.1 1.1 1.5 1.1
Neuroticism (Nagel 2018) 0.3 0.7 1.5 1.1 1.0 0.3 -0.7 0.9 0.8 1.2 1.1 0.1 -0.3 0.9 0.8 1.0 1.2 0.8 0.7 0.3 0.8 0.8 0.6 0.7 0.8
Schizophrenia (2018) 0.2 0.4 1.2 -0.6 -0.4 0.6 0.0 0.2 -0.7 -0.5 -0.7 0.2 -1.1 -0.6 -0.7 -0.6 0.2 -0.6 -0.5 -0.6 -0.6 -0.6 -0.7 -0.6 -0.7
Schizophrenia vs Biploar Disorder 0.2 0.2 1.9 0.6 -0.4 0.1 0.0 -0.5 -0.1 -0.8 -0.3 1.4 -0.3 -0.0 -0.2 -0.2 0.0 -0.3 0.4 0.6 0.3 -0.0 0.1 0.3 -0.1
Worry (Nagel 2018) 0.2 0.5 1.4 0.7 0.4 0.2 -1.1 0.9 0.8 0.7 0.8 0.3 0.1 0.7 0.8 0.9 1.2 0.4 0.5 -0.2 0.5 0.7 0.7 0.4 0.6
Alzheimer’s Disease (in mother) 0.4 0.5 2.0 0.8 0.4 1.4 1.0 0.1 0.7 -0.2 -0.2 -0.0 1.3 0.6 0.8 0.5 0.3 0.4 0.9 0.3 0.9 0.7 0.3 0.6 0.6
Alzheimer’s Disease (in father) 1.4 1.5 2.7 1.0 1.3 0.7 -0.6 1.1 1.4 1.1 1.2 -1.2 -0.0 1.3 1.3 1.4 1.6 1.2 1.5 0.8 1.4 1.3 1.5 1.3 1.3
Alzheimer’s Disease (including proxy) 2.5 3.6 5.5 1.9 2.1 2.2 0.5 1.2 2.3 1.4 1.5 -1.4 1.1 2.1 2.3 2.1 2.1 1.8 2.2 1.5 2.2 2.2 2.0 2.1 2.1
Crohns Disease (2017) 0.4 0.8 3.6 1.9 0.8 -0.1 -0.8 0.9 0.5 -0.1 0.2 -0.3 0.1 0.5 0.4 0.5 1.4 0.6 1.5 1.8 1.3 0.5 0.3 1.2 0.4
Irritable Bowel Disease (IBD) 1.3 3.1 7.8 2.4 1.8 0.9 -1.2 2.1 1.6 1.4 1.8 -1.5 0.0 1.7 1.7 1.5 2.8 2.0 2.2 1.9 2.1 1.6 1.5 1.9 1.6
Ulcerative Colitis (UC) 1.7 3.2 7.2 1.8 1.8 1.4 -0.8 2.3 1.7 1.8 2.3 -1.9 0.1 1.9 1.9 1.8 2.7 2.3 1.6 1.1 1.8 1.8 1.7 1.6 1.9
Major Depression (MDD) 1.2 1.4 3.3 -1.1 -1.4 -1.5 0.0 -0.6 -1.0 -1.0 -1.8 1.7 0.3 -1.0 -1.1 -1.1 -1.4 -1.7 -1.2 -1.5 -1.1 -1.0 -1.0 -1.2 -1.0
Reaction Time 0.7 1.3 2.5 1.4 1.3 0.3 -0.4 1.0 1.3 0.7 0.3 -0.5 1.5 1.2 1.1 1.1 1.3 1.1 1.4 1.6 1.3 1.2 0.9 1.3 1.1
Verbal and Numeric Reasoning (VNR) 2.4 5.7 16.9 1.6 2.7 3.7 2.1 3.8 1.9 2.3 2.7 -4.1 -0.4 1.9 2.1 2.2 1.7 2.7 1.8 2.3 1.8 1.9 2.2 2.1 1.9
Breast Cancer 0.0 0.1 0.4 0.6 0.1 -0.2 -0.2 -0.0 0.2 0.1 -0.0 -0.1 0.5 0.2 0.1 0.1 0.4 0.4 0.4 0.1 0.5 0.2 -0.1 0.3 0.2
Ovarian Cancer 0.2 0.3 1.8 0.6 0.5 0.9 1.4 1.0 0.2 1.0 -0.4 0.0 0.4 0.4 0.2 0.2 -0.5 0.3 0.3 0.7 0.3 0.3 0.3 0.2 0.4
Prostate Cancer 2.2 3.0 5.2 -1.4 -1.9 -1.6 0.4 -2.0 -1.9 -1.9 -2.3 2.1 -0.5 -1.8 -1.9 -1.9 -2.1 -1.9 -1.5 -1.7 -1.6 -1.8 -1.8 -1.4 -1.8
Age at First Birth 1.2 1.8 3.9 1.6 1.3 0.8 -0.7 0.9 1.2 1.8 1.3 -0.3 -0.0 1.5 1.6 1.6 2.0 1.1 1.6 1.6 1.6 1.6 1.2 1.4 1.3
Bipolar Disorder (2011) 0.9 0.9 2.2 -0.7 -1.0 -1.5 0.0 -1.3 -0.9 -1.1 0.0 1.3 0.2 -0.8 -0.8 -0.8 -0.8 -1.2 -0.7 -1.5 -0.7 -0.9 -0.9 -0.8 -0.9
Body Mass Index (BMI) (2010) 0.4 0.6 1.4 0.9 0.8 0.2 0.1 0.1 1.0 0.1 -0.1 0.2 0.5 1.0 1.0 0.9 -0.1 0.5 1.1 0.7 1.0 1.1 1.2 1.1 1.0
Coronary Artery Disease (CAD) 3.5 4.2 8.6 -2.9 -1.9 -1.9 0.0 -1.8 -2.0 -2.1 -1.5 0.5 -1.5 -2.0 -1.9 -2.3 -2.0 -2.2 -2.6 -2.5 -2.7 -2.2 -1.7 -2.4 -2.5
Crohns Disease (2012) 0.7 1.2 5.4 1.4 1.2 0.3 0.0 1.1 0.7 0.9 -0.0 -0.9 1.3 0.7 0.6 0.8 1.4 0.8 1.3 2.3 1.2 0.7 1.0 1.4 0.7
Mean Putamen Volume 1.2 1.4 2.5 -1.2 -0.9 -0.6 0.0 -0.3 -1.4 -0.9 -1.5 0.1 -1.0 -1.4 -1.6 -1.5 -1.6 -1.4 -1.1 -0.6 -1.3 -1.4 -1.4 -1.2 -1.5
Fasting Glucose 1.0 1.2 4.0 0.8 1.1 1.6 1.0 1.9 0.6 0.9 0.8 -2.0 -1.3 0.6 0.5 0.9 0.7 1.1 1.0 1.8 0.8 0.6 1.0 1.1 0.6
HbA1C 0.4 0.4 1.8 -0.3 -0.8 -0.9 0.6 -1.3 -0.3 0.1 -0.8 0.3 1.0 -0.3 -0.4 -0.4 -1.2 -0.1 -0.1 -0.4 -0.2 -0.4 -0.9 -0.6 -0.3
HDL Cholesterol 0.2 0.3 0.9 0.2 0.8 0.4 -0.1 0.7 0.4 0.8 0.4 -0.7 0.3 0.6 0.4 0.5 1.0 0.2 0.3 0.7 0.4 0.7 0.6 0.3 0.6
LDL Cholesterol 0.2 0.3 1.6 0.2 0.7 -0.1 0.1 -0.3 0.7 0.4 0.3 -1.1 -1.3 -0.0 0.8 0.6 -0.5 0.7 0.1 0.7 0.4 -0.0 -0.4 0.3 -0.0
Lupus 0.3 0.4 1.8 -1.2 -0.1 -0.5 -1.4 -0.2 -0.2 0.2 -0.1 -0.0 -0.6 -0.3 -0.1 -0.2 0.6 -0.6 -0.6 -1.1 -0.7 -0.3 -0.6 -0.8 -0.4
Neuroticism (2016) 0.5 0.7 1.4 0.8 0.7 -0.1 0.0 -0.4 1.2 0.6 1.1 0.6 -1.0 0.9 1.1 1.0 0.6 0.5 1.1 0.2 1.2 1.0 0.8 0.9 0.9
Primary Biliary Cirrhosis 1.6 2.3 3.7 -1.5 -1.7 -1.5 0.0 -1.9 -1.4 -1.8 -1.4 1.6 0.1 -1.4 -1.4 -1.5 -0.6 -1.6 -1.7 -1.9 -1.6 -1.5 -1.8 -1.9 -1.5
Rheumatoid Arthritis 1.0 1.4 2.6 -1.6 -1.1 -0.5 0.0 -1.2 -1.3 -1.0 -0.7 -0.6 -1.5 -1.4 -1.3 -1.4 -0.6 -1.0 -1.4 -1.2 -1.5 -1.4 -1.3 -1.4 -1.4
Schizophrenia (2014) 0.4 1.0 2.1 -0.9 -1.0 -0.2 0.0 -0.5 -1.0 -1.3 -1.1 1.0 -1.4 -1.0 -1.0 -1.0 -0.3 -1.1 -1.0 -1.1 -1.0 -1.0 -1.2 -1.1 -1.0
Triglycerides 0.1 0.1 0.6 -0.2 0.0 -0.2 -0.6 0.7 -0.1 -0.1 0.2 0.3 0.1 0.3 0.1 -0.1 -0.3 -0.3 0.1 -0.1 -0.1 0.3 0.8 0.2 0.3
Type 2 Diabetes (T2D) (2012) 0.3 0.4 6.6 -0.1 0.1 0.7 0.0 0.7 -0.2 0.1 0.3 0.3 -2.6 -0.3 -0.1 -0.3 0.4 -0.2 -0.1 0.3 0.3 0.1 -0.1 0.2 0.3
Ulcerative Colitis 1.1 1.7 3.9 1.1 1.4 0.9 0.0 1.6 1.2 1.8 1.6 -1.4 0.6 1.4 1.3 1.2 2.0 1.6 1.0 0.9 1.1 1.3 1.3 1.0 1.4
Blood Eosinophil Count 0.3 2.1 3.8 -1.4 -1.6 -1.8 -0.6 -1.9 -1.4 -1.3 -0.7 1.2 -1.6 -1.5 -1.4 -1.4 -1.1 -1.2 -1.7 -1.9 -1.6 -1.5 -1.4 -1.7 -1.3
Blood Platelet Count 0.0 0.3 1.2 -0.6 -0.4 -1.1 -0.8 -0.5 -0.2 -0.1 -0.6 0.5 0.3 -0.3 -0.3 -0.3 -0.7 -0.2 -0.5 -0.6 -0.5 -0.3 -0.0 -0.4 -0.3
Blood Red Count 0.1 0.9 2.8 -1.4 -0.7 -0.3 -0.2 0.3 -1.0 -0.5 -0.3 -1.0 0.2 -1.1 -0.8 -1.0 -0.2 -0.6 -1.6 -0.9 -1.4 -1.0 -1.4 -1.7 -1.1
Blood White Count 0.4 2.8 5.3 -2.3 -1.6 -1.2 -0.7 -1.1 -1.8 -0.6 -1.1 1.7 -1.4 -1.7 -1.6 -1.7 -0.9 -1.7 -2.2 -2.3 -1.8 -1.7 -2.0 -2.2 -1.5
Heel T-Score 0.0 0.3 2.8 -0.5 -0.3 -1.1 -1.7 -0.4 -0.3 0.1 -0.6 0.5 -0.6 -0.4 -0.4 -0.4 -0.7 -0.5 -0.3 0.0 -0.6 -0.4 -0.4 -0.5 -0.3
BMI 0.2 1.2 3.0 -1.7 -0.7 -1.4 -1.4 -1.1 -0.7 0.7 -0.3 1.6 1.7 -0.6 -0.6 -0.6 -0.5 -1.1 -1.6 -1.1 -1.0 -0.6 -0.9 -1.3 -0.5
Height 0.0 0.2 1.7 0.3 -0.4 -1.1 -1.2 -0.3 -0.0 -0.1 -0.3 1.3 0.0 -0.1 -0.0 0.1 -0.1 -0.2 0.0 -0.1 0.2 -0.0 0.4 0.3 -0.1
Waist Hip Ratio (WHR) 0.1 0.4 3.3 -0.3 -0.3 -0.9 -1.5 0.1 -0.2 0.0 -0.3 0.8 -1.8 -0.2 -0.3 -0.2 0.7 -0.6 -0.1 -0.5 -0.1 -0.2 -0.0 -0.1 -0.2
Systolic Blood Pressure 0.0 0.2 1.3 -1.2 -0.3 -1.1 -0.0 -0.7 -0.5 -0.1 -0.4 0.1 -0.1 -0.3 -0.3 -0.4 0.1 -0.2 -0.7 -0.4 -0.6 -0.3 -0.3 -0.4 -0.3
Smoking Status 0.1 0.2 1.5 0.1 0.3 -0.1 -0.9 0.5 0.0 0.5 0.0 0.3 -1.2 0.2 -0.0 0.1 0.6 0.1 0.3 0.5 0.3 0.1 0.4 0.4 0.1
Allergy or Eczema 0.5 1.2 2.7 1.2 1.1 1.1 0.8 1.1 1.0 1.6 0.9 -1.3 0.1 1.1 1.0 1.2 0.1 1.3 1.1 1.1 1.3 1.1 1.2 1.2 1.1
Cardiovascular Disease 0.2 0.7 1.7 -1.3 -0.7 -1.2 -1.2 -0.9 -0.9 -0.4 -0.3 -0.0 -0.6 -0.9 -0.7 -0.8 -0.2 -0.5 -1.0 -0.5 -1.0 -0.9 -0.7 -0.9 -0.9
Hypothyroidism (self reported) 0.9 2.1 3.5 1.4 1.4 0.8 1.3 0.3 1.7 1.8 0.6 -0.6 -0.6 1.7 1.6 1.8 1.2 1.6 1.4 1.9 1.6 1.7 1.7 1.6 1.7
Respiratory disease 1.5 3.3 6.2 1.5 1.9 1.6 1.3 1.2 2.0 1.8 2.5 -1.4 1.8 2.0 1.9 2.0 1.4 2.1 1.7 1.6 2.0 2.0 1.8 1.8 2.0
Type 2 Diabetes (T2D) (2018) 0.1 0.2 1.0 0.4 0.4 0.3 -0.2 1.0 -0.0 0.4 -0.1 -1.0 -1.0 0.1 0.0 0.2 0.1 0.6 0.4 0.9 0.2 0.0 0.0 0.3 -0.0
Lung FEV1/FVC ratio 0.1 0.6 1.3 1.1 0.8 1.0 0.6 0.9 0.4 0.3 0.3 -1.1 0.9 0.5 0.5 0.4 1.0 0.8 1.1 1.1 1.0 0.5 0.6 1.0 0.4
Lung FVC 0.7 3.7 7.9 1.8 2.2 2.5 0.0 2.2 1.9 1.8 1.9 -2.8 0.2 2.0 1.8 1.9 1.9 2.1 1.7 1.5 1.8 2.0 2.3 1.9 2.0
Neuroticism 0.5 1.3 2.5 1.6 1.2 0.7 -0.5 1.2 1.2 1.5 1.4 -0.7 0.4 1.2 1.2 1.3 1.6 1.2 1.1 0.6 1.3 1.2 0.8 1.0 1.1
Chronotype (morning person) 0.1 0.2 0.7 0.4 -0.0 0.1 0.3 0.4 -0.3 0.1 0.6 -0.7 -0.7 -0.3 -0.3 -0.2 -0.8 0.1 -0.2 0.4 -0.1 -0.3 -0.4 -0.3 -0.3
Hair Pigment 0.0 0.9 3.3 1.0 1.2 0.3 -0.1 1.2 0.7 0.3 -0.3 -1.8 1.7 0.7 0.5 0.6 0.2 1.3 0.7 1.2 0.7 0.7 1.3 1.0 0.9
Tanning 0.6 7.3 10.4 -3.0 -3.1 -2.4 -1.9 -2.9 -2.9 -2.4 -2.0 2.6 -2.6 -2.8 -2.7 -2.8 -1.8 -2.7 -3.0 -2.7 -3.2 -2.8 -2.7 -3.0 -2.8
Hand grip strength (left) 0.1 0.1 1.3 -0.4 0.1 -0.4 0.2 -0.2 0.2 0.7 0.0 -0.1 1.1 0.2 0.3 0.2 -0.2 -0.1 -0.3 -0.3 -0.2 0.2 -0.1 -0.3 0.1
Number of treatments/medications taken 0.2 0.4 1.5 0.5 0.5 -0.6 -0.8 -0.0 0.5 1.1 0.2 0.1 1.2 0.4 0.5 0.6 1.0 0.7 0.6 0.6 0.7 0.4 0.3 0.7 0.5
Average weekly spirits intake 1.6 1.9 4.8 2.2 1.0 0.5 -1.0 1.1 1.6 0.6 0.9 0.4 1.9 1.5 1.4 1.5 1.7 1.2 1.8 1.1 1.8 1.5 1.1 1.7 1.4
Sensitivity / hurt feelings 0.1 0.2 1.7 0.7 0.1 -0.7 -1.3 -1.0 0.2 -0.0 0.2 0.5 0.2 0.2 0.3 0.1 0.5 -0.0 0.5 0.3 0.6 0.2 -0.1 0.3 0.1
Frequency of depressed mood in last 2 weeks 0.3 0.5 6.1 -0.3 -0.1 -0.7 -1.4 0.1 -0.4 -0.1 -0.2 0.6 -2.5 -0.4 -0.3 -0.3 -0.4 -0.4 -0.3 -0.1 -0.4 -0.4 -0.5 -0.3 -0.3
Hearing difficulty/problems: Yes 1.8 2.8 6.1 1.6 1.8 1.2 1.1 1.1 2.1 2.5 1.3 -0.9 1.3 1.9 2.0 1.9 2.1 1.7 1.5 1.2 1.9 1.9 1.4 1.5 2.0
Relative age of first facial hair 0.1 0.1 0.8 0.1 0.3 -0.9 -0.7 0.1 0.3 0.5 0.0 -0.1 0.0 0.2 0.2 0.2 0.5 0.3 -0.2 0.5 0.0 0.2 0.5 0.1 0.3
Other serious medical condition/disability diagnosed by doctor 1.8 2.3 4.2 2.0 1.3 -0.4 -1.1 0.4 2.0 1.1 1.0 0.2 -0.2 1.8 1.9 1.9 1.5 1.6 2.0 1.1 1.9 1.8 1.9 2.0 1.7
Ever used hormone-replacement therapy (HRT) 1.7 2.2 6.9 -1.4 -1.4 -2.2 -2.6 -1.9 -1.2 -1.2 -1.7 1.6 -0.3 -1.3 -1.3 -1.2 -1.2 -1.5 -1.3 -1.9 -1.3 -1.3 -1.2 -1.4 -1.2
Ever had hysterectomy (womb removed) 0.4 0.4 2.4 0.3 0.8 0.9 -0.6 1.0 0.1 0.5 1.2 -1.5 0.5 0.2 0.3 0.1 1.0 0.8 0.3 0.7 0.2 0.1 0.2 0.3 0.2
Systolic blood pressure, automated reading 0.0 0.1 0.8 -0.9 0.2 -0.7 -0.5 -0.2 0.1 -0.0 -0.3 -0.7 0.5 -0.0 0.0 -0.0 0.0 0.0 -0.4 -0.3 -0.3 -0.0 0.0 -0.2 -0.0
Eye problems/disorders: Diabetes related eye disease 0.3 0.3 1.0 0.9 0.2 0.5 0.8 -0.4 0.3 0.6 0.2 0.7 -0.2 0.5 0.3 0.4 0.9 0.4 0.7 1.0 0.8 0.5 0.3 0.6 0.6
Angina 0.8 1.1 4.9 -0.3 -0.9 -1.5 -0.2 -1.9 -1.0 -1.7 -1.7 2.2 -1.0 -0.8 -1.0 -0.7 -0.2 -1.2 0.0 0.2 -0.2 -0.8 -0.5 0.0 -0.8
Medication for hormone replacement therapy 0.4 0.5 3.1 -0.3 0.7 -0.2 -0.6 0.1 0.6 1.8 1.1 -0.2 1.1 0.6 0.5 0.7 0.5 0.3 -0.2 -0.7 0.5 0.6 0.4 -0.1 0.9
Vitamin and mineral supplements 0.4 0.6 1.0 0.8 0.8 0.7 0.2 0.5 0.9 0.2 1.0 -0.9 0.5 0.9 0.9 0.8 -0.1 0.8 0.8 0.9 0.8 0.9 0.9 0.8 0.8
Supplements: Zinc 0.2 0.3 1.9 0.5 0.4 0.8 1.4 0.4 0.2 0.5 -0.2 -0.3 0.7 0.3 0.2 0.3 0.4 0.4 0.3 0.1 0.4 0.3 0.6 0.4 0.4
Medication: Co-codamol 1.9 2.2 5.7 1.3 1.6 1.4 -0.7 1.8 1.4 1.4 1.2 -2.4 2.1 1.2 1.3 1.1 1.8 1.8 1.6 1.3 1.4 1.2 1.0 1.2 1.1
Medication: Metformin 0.1 0.2 1.4 0.0 0.2 -0.1 0.7 0.1 -0.3 -0.2 -0.3 -0.7 -1.2 -0.1 -0.1 -0.1 -1.0 0.1 -0.0 0.2 -0.1 -0.1 -0.1 -0.1 -0.1
Diabetes (father) 0.8 1.0 1.8 1.2 0.8 1.1 1.0 1.2 1.3 1.1 0.9 -0.0 1.4 1.1 1.3 1.1 0.8 1.1 0.9 0.4 0.9 1.1 0.8 0.8 1.0
Diabetes (mother) 1.2 1.5 3.0 -1.5 -1.2 -1.4 -1.0 -1.6 -1.3 -0.1 -0.5 0.5 -1.6 -1.3 -1.1 -1.1 -1.5 -1.0 -1.2 -0.9 -1.1 -1.3 -1.7 -1.3 -1.3
Severe depression (siblings) 0.3 0.3 2.2 -0.3 0.4 0.5 -0.6 0.5 0.2 0.5 0.4 -1.4 -1.5 0.1 0.3 0.1 0.8 0.2 -0.3 0.0 -0.3 0.1 0.2 -0.3 -0.0
Pack years adult smoking proportion 0.3 0.5 1.2 0.5 0.8 -0.6 -1.1 -0.3 1.0 0.6 0.3 -0.4 0.1 1.0 0.8 0.7 0.1 0.8 0.6 0.6 0.6 1.0 0.8 0.6 0.9
Impedance of leg (right) 0.1 0.6 2.6 1.2 0.6 0.7 -0.8 1.6 0.6 -0.4 0.1 -0.9 -0.7 0.6 0.5 0.5 0.8 0.8 1.2 0.9 0.8 0.6 0.6 1.0 0.5
Leg fat-free mass (left) 0.3 1.3 3.8 -1.3 -1.2 -1.8 -0.1 -1.9 -1.0 -0.2 -0.5 1.7 0.6 -1.0 -0.9 -1.0 -1.2 -1.1 -1.5 -1.2 -1.0 -1.0 -1.0 -1.2 -0.9
Trunk fat percentage 0.1 0.5 9.6 0.1 -0.3 -0.3 -0.1 -0.3 0.2 -0.1 0.6 0.8 3.1 0.0 0.3 0.1 -0.0 -0.1 0.0 -0.6 0.2 0.0 -0.2 0.0 -0.1
Hand grip strength (right) 0.1 0.2 1.2 -0.0 0.2 -0.7 0.1 -0.7 0.6 0.7 -0.0 1.1 0.7 0.5 0.6 0.6 0.2 -0.1 0.1 0.3 0.2 0.6 0.1 0.1 0.5
Townsend deprivation index at recruitment 0.6 0.9 11.2 -0.4 0.5 1.1 -1.3 0.6 -0.1 0.8 0.6 -1.3 -3.3 -0.1 0.0 -0.0 1.2 0.3 -0.2 -0.5 -0.1 -0.1 0.1 -0.1 -0.0
Current tobacco smoking 0.2 0.4 1.3 0.4 0.7 -0.3 -1.1 -0.1 0.5 0.7 -0.0 -0.2 -0.2 0.6 0.4 0.5 1.1 0.4 0.9 0.4 0.7 0.6 0.7 0.8 0.6
Average weekly fortified wine intake 0.1 0.1 1.3 0.2 -0.3 -0.6 0.9 -0.3 -0.1 0.1 0.0 0.2 1.1 -0.2 -0.3 -0.2 -0.3 -0.0 -0.2 0.1 -0.3 -0.2 0.1 -0.2 -0.1
Maternal smoking around birth 0.1 0.1 1.3 -0.0 -0.1 0.8 1.1 -0.1 0.0 0.2 0.7 -0.1 0.4 0.0 0.2 0.1 0.5 -0.0 -0.0 -0.5 0.1 0.1 0.0 -0.1 -0.1
Fed-up feelings 0.2 0.3 1.9 0.1 0.5 0.5 0.8 0.2 0.4 1.1 0.6 -0.2 -1.4 0.3 0.4 0.4 0.9 0.6 -0.1 -0.6 0.2 0.3 -0.0 -0.1 0.4
Frequency of unenthusiasm / disinterest in last 2 weeks 0.8 1.1 5.7 -0.9 -0.5 -1.4 -2.4 0.3 -0.9 0.2 -0.6 0.4 -2.3 -0.9 -0.9 -0.7 -0.5 -0.6 -1.0 -0.6 -0.8 -0.9 -1.1 -0.9 -0.7
Relative age voice broke 0.1 0.2 0.8 0.1 0.3 0.0 -0.3 0.1 0.3 0.7 0.9 -0.0 -0.9 0.4 0.5 0.4 0.9 0.4 0.0 -0.2 0.1 0.3 0.5 0.0 0.4
Taking other prescription medications 1.9 2.9 5.6 2.4 1.6 0.6 1.0 0.5 1.8 1.4 1.1 -0.9 1.9 1.7 1.8 1.8 1.7 2.0 2.3 1.8 2.1 1.7 1.8 2.3 1.6
Age when periods started (menarche) 0.2 0.4 1.7 -0.6 -0.2 -0.5 -0.1 -0.9 -0.4 -0.5 -0.7 1.2 -1.0 -0.4 -0.5 -0.5 -1.3 -0.6 -0.6 -0.3 -0.5 -0.4 -0.2 -0.5 -0.2
Bilateral oophorectomy (both ovaries removed) 0.8 0.9 2.7 0.7 1.0 0.9 -0.2 1.0 0.6 0.8 1.6 -1.6 1.6 0.7 0.8 0.7 0.8 1.4 0.6 0.5 0.7 0.7 1.0 0.8 0.8
Heel bone mineral density (BMD) T-score, automated (left) 0.1 0.2 1.1 -0.2 0.1 -0.5 0.5 -0.5 0.0 0.5 -0.4 1.1 0.9 0.2 0.1 0.2 -0.5 -0.3 0.1 0.5 0.1 0.2 -0.2 -0.0 0.3
Tinnitus: Yes, but not now, but have in the past 1.6 1.8 4.4 -1.6 -1.5 -0.7 -0.9 -0.4 -1.4 -0.8 -0.4 1.2 -1.5 -1.4 -1.3 -1.3 -1.2 -1.4 -1.6 -2.1 -1.4 -1.4 -1.5 -1.6 -1.3
Qualifications: CSEs or equivalent 0.2 0.2 3.5 0.3 -0.2 -0.0 0.2 -0.1 -0.1 0.5 0.3 0.7 -1.9 0.0 -0.0 0.0 0.1 0.1 0.1 -0.1 0.0 -0.0 -0.0 0.1 -0.0
Serious illness, injury or assault to yourself 1.5 1.8 3.9 1.7 1.5 0.7 -0.8 -0.1 1.8 1.4 1.3 0.4 -0.8 1.7 1.5 1.6 0.6 0.9 1.6 1.6 2.0 1.7 0.9 1.5 1.7
High blood pressure 0.5 1.3 2.4 -1.5 -1.1 -1.1 0.0 -1.4 -1.4 -1.0 -1.5 1.0 -0.8 -1.3 -1.4 -1.3 -0.6 -1.4 -1.1 -0.4 -1.3 -1.3 -1.0 -1.0 -1.2
Hayfever, allergic rhinitis or eczema 0.5 1.1 3.2 1.4 0.8 1.5 1.8 1.0 0.7 1.4 0.7 -1.0 -0.3 0.8 0.8 0.9 0.6 1.1 1.3 1.2 1.2 0.8 1.1 1.3 0.8
Multivitamins +/- minerals 2.1 2.7 4.2 -2.0 -1.8 -1.5 0.1 -2.0 -1.6 -0.9 -1.7 2.0 -1.0 -1.7 -1.6 -1.6 -0.6 -1.9 -1.9 -1.9 -1.7 -1.7 -1.8 -1.9 -1.6
Stomach or abdominal pain in last month 0.7 0.8 3.5 1.0 0.8 -0.2 -0.6 0.1 1.1 0.8 -0.0 1.9 -0.8 1.1 1.0 1.0 1.0 -0.0 1.1 0.0 1.2 1.0 0.7 0.9 1.1
Supplements: Glucosamine 1.0 1.4 3.6 -0.2 -1.3 -1.9 -1.6 -1.3 -1.3 -1.4 -1.3 1.4 -0.7 -1.2 -1.3 -1.1 -1.0 -1.0 -0.6 -0.9 -0.8 -1.2 -1.2 -0.7 -1.1
Diverticular disease/diverticulitis (self-reported) 1.1 1.4 2.3 1.1 1.2 0.9 0.5 1.2 1.5 0.3 0.8 -1.0 -0.0 1.3 1.4 1.3 0.6 1.4 1.3 1.5 1.2 1.3 1.5 1.5 1.3
Medication: Atenolol 1.3 1.7 3.1 -1.4 -1.3 -1.8 -0.9 -1.2 -1.4 -1.5 -1.5 1.2 0.1 -1.4 -1.3 -1.4 -1.4 -1.5 -1.0 -0.9 -1.0 -1.3 -1.4 -1.2 -1.3
Medication: Levothyroxine sodium 0.4 0.7 1.3 0.8 1.0 0.2 0.6 0.3 1.1 0.9 0.3 0.1 -0.4 1.0 1.0 1.1 0.5 0.9 1.0 1.0 1.0 1.0 1.1 1.1 1.1
Sitting height 0.1 0.9 2.1 -0.8 -0.9 -0.9 0.0 -0.8 -1.0 -0.9 -0.9 0.9 -1.4 -1.1 -1.1 -0.9 -1.0 -0.9 -1.0 -0.6 -1.0 -1.1 -1.0 -0.8 -1.1
Chronic bronchitis/emphysema (father) 0.1 0.2 1.1 0.2 0.1 -0.1 -0.9 -0.7 -0.0 -0.2 0.1 0.1 1.0 0.0 -0.1 -0.1 -0.8 0.1 0.0 0.2 0.0 0.0 0.4 0.2 -0.0
High blood pressure (mother) 0.2 0.3 2.3 0.2 0.4 -1.1 -1.5 -0.2 0.1 0.3 0.2 -1.1 0.4 0.1 0.3 0.3 -0.2 0.5 0.2 0.7 0.1 0.1 -0.2 0.1 0.1
Body mass index (BMI) 0.3 1.1 4.5 -1.3 -1.0 -1.2 -0.1 -1.3 -0.7 -0.1 -0.6 1.8 2.1 -0.8 -0.7 -0.8 -1.0 -1.1 -1.2 -1.3 -0.8 -0.8 -0.8 -1.0 -0.8
Impedance of leg (left) 0.1 0.6 3.1 1.0 0.6 0.8 -0.6 1.8 0.6 -0.3 0.2 -1.0 -0.7 0.6 0.5 0.5 0.7 0.8 1.0 0.6 0.6 0.5 0.4 0.8 0.5
Leg predicted mass (left) 0.3 1.5 4.0 -1.4 -1.2 -1.9 -0.1 -2.0 -1.1 -0.3 -0.5 1.7 0.6 -1.1 -1.0 -1.1 -1.3 -1.1 -1.6 -1.3 -1.1 -1.1 -1.1 -1.3 -1.0
Trunk fat mass 0.2 0.8 5.9 -0.7 -0.9 -1.0 -0.2 -1.0 -0.5 -0.4 -0.2 1.4 2.4 -0.7 -0.4 -0.6 -0.9 -0.8 -0.8 -1.2 -0.5 -0.6 -0.8 -0.7 -0.7
Waist circumference 0.3 1.0 4.4 -1.0 -1.1 -1.4 -0.2 -1.2 -0.7 -0.3 -0.8 2.1 1.1 -0.8 -0.8 -0.9 -0.8 -1.1 -1.1 -1.3 -0.7 -0.8 -0.7 -0.9 -0.8
Number of incorrect matches in round 1.2 1.9 3.5 1.3 1.6 1.0 -0.6 1.4 1.4 1.6 1.1 -1.2 -0.4 1.6 1.3 1.4 1.2 1.4 1.4 1.7 1.4 1.6 1.9 1.6 1.6
Past tobacco smoking 0.1 0.2 3.0 -0.4 -0.3 -0.0 0.4 -0.8 -0.1 -0.3 -0.2 -0.5 1.7 -0.1 -0.2 -0.2 -0.3 -0.1 -0.1 -0.7 -0.0 -0.1 -0.1 -0.1 -0.1
Alcohol usually taken with meals 4.5 7.2 11.8 2.2 2.9 3.0 1.4 2.7 2.7 3.2 3.1 -3.4 2.9 2.6 2.8 2.8 2.6 3.0 2.2 2.4 2.6 2.6 2.4 2.4 2.6
Nervous feelings 0.1 0.2 0.8 0.5 0.2 -0.0 -0.2 0.5 0.6 0.4 0.2 -0.0 0.9 0.6 0.6 0.5 0.7 0.5 0.4 -0.6 0.6 0.6 0.1 0.2 0.4
Frequency of tenseness / restlessness in last 2 weeks 0.4 0.7 2.7 1.6 0.7 0.2 0.2 0.4 0.5 0.0 0.2 0.1 -1.6 0.7 0.5 0.7 0.4 0.7 1.1 1.4 0.8 0.6 0.9 1.2 0.7
Hearing difficulty/problems with background noise 0.6 0.9 2.8 0.5 1.0 0.7 0.7 0.4 1.2 1.5 0.5 -0.9 1.1 1.1 1.1 1.0 1.7 0.8 0.8 0.3 1.1 1.1 0.4 0.5 1.0
Hair/balding pattern: Pattern 2 0.2 0.2 1.1 -0.4 -0.3 -0.9 -0.2 -1.0 -0.2 0.2 -0.5 0.8 -0.1 -0.1 -0.2 -0.1 0.8 -0.5 -0.2 -0.6 -0.1 -0.1 -0.3 -0.3 -0.1
Had menopause 1.0 1.2 2.7 1.1 1.4 0.7 0.4 1.0 1.3 0.7 0.6 -1.6 0.9 1.2 1.1 1.1 1.3 1.0 1.3 1.2 1.2 1.2 1.2 1.1 1.1
Had other major operations 0.3 0.4 1.7 -0.4 0.4 0.6 -0.4 1.1 0.6 0.6 0.6 -0.3 1.3 0.6 0.7 0.6 0.8 0.1 0.1 -0.6 0.4 0.6 0.5 0.2 0.6
Forced vital capacity (FVC) 0.2 0.8 11.4 -0.9 -0.3 -0.0 -0.8 -0.1 -0.2 0.0 0.1 0.4 -3.4 -0.2 -0.3 -0.3 -0.4 -0.4 -1.0 -1.2 -0.7 -0.2 -0.1 -0.8 -0.2
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.6 1.5 -1.0 -0.5 -1.2 -0.3 -0.9 -0.7 0.0 -1.0 0.8 0.5 -0.5 -0.6 -0.4 -1.0 -0.8 -0.8 -0.3 -0.7 -0.5 -1.0 -0.9 -0.4
Ever unenthusiastic/disinterested for a whole week 0.1 0.2 1.9 -0.2 -0.0 -0.3 -0.4 -0.9 -0.1 -0.2 -0.1 0.6 -1.4 0.0 -0.0 -0.0 -0.2 -0.2 -0.2 -0.2 -0.0 0.0 -0.1 -0.1 0.1
Qualifications: None of the above 1.2 2.7 5.2 -1.8 -1.8 -1.8 -1.8 -1.8 -1.4 -1.4 -1.5 1.8 -0.1 -1.6 -1.5 -1.7 -0.9 -1.8 -1.8 -2.3 -1.7 -1.6 -1.3 -1.8 -1.6
Financial difficulties in last 2 years 0.6 0.8 1.7 1.0 1.1 -0.0 -0.4 0.6 0.7 0.5 0.8 -1.0 0.4 0.9 0.6 0.9 0.7 1.0 1.1 1.0 1.0 0.8 1.3 1.2 1.0
Mouth/teeth dental problems 1.9 3.0 4.1 -1.7 -2.0 -1.1 1.0 -1.7 -2.0 -1.9 -1.4 1.8 -1.4 -1.8 -2.0 -1.9 -1.8 -1.7 -1.9 -1.6 -1.8 -1.8 -1.7 -1.9 -1.7
Heart attack 0.9 1.2 2.4 -0.7 -1.1 -1.1 0.1 -0.8 -1.5 -1.4 -0.8 0.2 -0.4 -1.6 -1.4 -1.4 -0.7 -0.9 -0.8 -0.6 -1.1 -1.5 -1.3 -0.9 -1.5
Allergy 0.2 0.4 3.1 -0.9 -0.2 -0.7 -1.8 -0.1 -0.1 -0.4 -0.2 0.5 -0.1 -0.1 -0.0 -0.2 0.3 -0.5 -0.7 -1.0 -0.6 -0.1 -0.3 -0.7 0.0
Pain all over the body in last month 0.5 0.5 1.9 -0.4 -0.9 -0.8 0.1 -1.4 -0.5 -1.0 -0.8 1.3 0.6 -0.5 -0.6 -0.5 -0.6 -0.6 -0.4 -1.2 -0.4 -0.5 -0.6 -0.5 -0.4
Diabetes (self-reported) 0.3 0.5 1.9 1.0 0.6 0.4 -0.0 0.9 0.3 0.4 -0.0 -0.8 -1.3 0.4 0.3 0.5 0.2 0.7 1.0 1.4 0.7 0.4 0.4 0.8 0.3
Hayfever/allergic rhinitis (self-reported) 1.8 2.4 5.4 -1.8 -1.4 -0.5 1.3 -1.0 -1.6 -0.4 -1.6 0.5 -1.9 -1.4 -1.4 -1.6 -2.3 -1.5 -1.9 -2.1 -1.6 -1.4 -1.7 -1.8 -1.4
Medication: Ramipril 1.2 1.6 3.2 -1.4 -1.4 -1.5 -0.2 -1.4 -1.5 -1.4 -1.3 1.8 -1.1 -1.4 -1.3 -1.2 -0.4 -1.4 -1.2 -0.7 -1.2 -1.4 -1.0 -0.9 -1.2
Medication: Simvastatin 1.6 2.4 4.2 2.0 1.8 0.0 -1.2 0.6 1.5 1.3 1.5 -2.1 -0.3 1.5 1.6 1.6 1.6 2.1 1.8 1.9 1.6 1.4 1.5 1.8 1.4
Fluid intelligence score 1.3 2.8 6.3 1.1 1.9 2.5 2.5 2.2 1.4 1.3 1.4 -2.1 0.8 1.6 1.5 1.6 0.7 1.5 1.5 1.7 1.3 1.6 1.8 1.7 1.6
Illnesses of siblings 0.1 0.2 2.7 -0.2 -0.1 0.8 1.6 0.1 -0.3 -0.2 -0.1 0.1 -0.1 -0.1 -0.3 -0.1 -0.2 -0.1 -0.4 0.2 -0.3 -0.1 0.2 -0.2 -0.1
Neuroticism score 0.1 0.2 1.8 0.2 -0.1 0.3 0.2 0.4 -0.1 0.3 0.3 0.0 -1.4 -0.2 -0.0 -0.0 0.5 0.1 -0.1 -0.7 -0.1 -0.2 -0.7 -0.4 -0.2
Weight 0.4 1.9 4.4 -1.5 -1.5 -1.9 -0.1 -1.9 -1.2 -0.6 -0.9 2.1 1.3 -1.3 -1.2 -1.2 -1.5 -1.4 -1.6 -1.6 -1.2 -1.2 -1.3 -1.4 -1.2
Impedance of arm (right) 0.3 1.2 3.9 2.0 0.9 1.0 0.7 0.8 1.0 -0.2 1.5 -1.0 -0.1 1.0 1.0 1.0 1.2 1.2 1.6 0.8 1.3 1.0 1.0 1.3 0.9
Arm fat percentage (right) 0.1 0.5 6.0 -0.4 -0.6 -0.6 0.4 -0.8 -0.1 -0.3 0.1 1.4 2.4 -0.3 -0.1 -0.3 -0.6 -0.5 -0.4 -1.0 -0.2 -0.3 -0.3 -0.4 -0.4
Trunk fat-free mass 0.5 2.6 4.8 -1.8 -1.7 -2.1 -0.5 -1.8 -1.6 -0.9 -1.6 1.8 -0.3 -1.7 -1.6 -1.7 -2.2 -1.6 -2.0 -1.3 -1.7 -1.6 -1.4 -1.7 -1.6
Hip circumference 0.2 0.7 5.9 -0.5 -0.7 -0.5 1.1 -0.9 -0.4 -0.4 -0.2 1.3 2.4 -0.5 -0.4 -0.5 -0.9 -0.4 -0.8 -0.7 -0.5 -0.5 -0.5 -0.5 -0.5
Time employed in main current job 0.4 0.5 2.0 -0.6 -0.9 -0.8 0.4 -1.4 -0.6 -0.1 -0.6 1.4 -0.9 -0.6 -0.7 -0.5 -0.1 -0.5 -0.5 -0.3 -0.5 -0.6 -0.7 -0.6 -0.5
Alcohol intake versus 10 years previously 1.1 1.6 5.2 -0.7 -1.1 -1.9 -1.0 -1.3 -0.8 -0.8 -1.5 2.3 -1.9 -0.9 -0.9 -1.1 -1.1 -1.4 -0.9 -1.7 -0.9 -0.9 -1.3 -1.0 -1.0
Father’s age at death 0.4 0.6 2.7 -0.3 -0.7 -0.4 0.9 -1.1 -0.7 -1.6 -0.5 -0.0 0.2 -0.6 -0.8 -0.8 -1.3 -0.4 -0.3 -0.3 -0.6 -0.7 -0.8 -0.5 -0.8
Worrier / anxious feelings 0.1 0.2 2.8 0.2 0.1 0.3 -0.5 0.7 -0.3 -0.4 0.1 -0.5 -1.7 -0.2 -0.1 -0.2 0.4 -0.1 0.2 -0.3 0.0 -0.2 -0.3 -0.1 -0.3
Frequency of tiredness / lethargy in last 2 weeks 0.3 0.5 1.4 1.1 0.4 -0.5 0.4 -0.1 0.3 0.8 -0.6 1.1 -1.0 0.5 0.3 0.6 0.4 0.4 1.0 0.6 1.0 0.4 0.8 1.2 0.6
Falls in the last year 0.3 0.4 2.0 0.4 0.5 -0.7 -0.9 -1.0 0.7 0.4 0.1 1.4 -0.1 0.6 0.6 0.5 0.6 0.0 0.7 0.6 0.7 0.6 0.4 0.6 0.6
Hair/balding pattern: Pattern 3 0.2 0.2 3.4 -0.1 0.1 0.3 -1.9 0.7 -0.3 0.1 0.2 -0.8 -0.3 -0.1 -0.2 -0.2 -0.4 0.1 -0.1 0.2 -0.2 -0.2 0.3 0.0 -0.1
Number of live births 0.8 1.1 9.3 -0.9 -0.9 -1.8 0.0 -3.0 -0.6 -0.6 -1.1 1.7 -0.2 -0.5 -0.6 -0.5 -1.1 -0.9 -0.8 -0.9 -0.7 -0.5 -0.5 -0.8 -0.4
Forced expiratory volume in 1-second (FEV1) 0.1 0.4 6.5 -0.7 0.1 0.6 -0.4 0.3 0.1 0.3 0.4 -0.0 -2.5 0.1 0.0 -0.0 0.0 -0.1 -0.7 -0.9 -0.3 0.1 0.2 -0.4 0.2
Pulse rate 0.7 1.1 2.9 0.6 1.2 0.0 -1.1 1.1 1.1 1.5 0.4 0.1 1.7 1.1 1.0 1.2 1.4 0.6 0.7 0.6 1.1 1.1 1.3 1.0 1.3
Happiness 1.4 1.7 3.5 0.8 1.4 1.5 -0.6 1.9 1.2 1.3 1.5 -1.5 -1.4 1.2 1.2 1.2 1.8 1.4 0.9 1.2 1.0 1.2 1.1 1.0 1.1
Noisy workplace 0.6 0.7 4.3 1.0 -0.4 -1.2 -2.1 -1.3 -0.2 -0.5 -0.7 2.1 0.5 -0.1 -0.2 -0.2 0.6 -0.3 0.8 0.3 0.5 -0.1 -0.1 0.6 -0.2
Qualifications: A levels/AS levels or equivalent 4.8 10.5 13.9 3.3 3.5 3.0 0.8 3.2 3.7 3.4 3.3 -2.4 2.1 3.7 3.7 3.7 2.1 3.3 3.5 3.2 3.5 3.7 3.7 3.4 3.6
Serious illness, injury or assault of a close relative in last 2 years 0.6 0.7 1.6 -1.1 -0.7 -1.1 -1.2 -0.3 -0.9 -0.7 -0.7 -0.2 -0.9 -0.9 -0.8 -0.8 -0.7 -0.7 -1.0 -1.1 -1.0 -0.9 -0.5 -0.9 -0.8
Mouth/teeth dental problems: Dentures 0.4 0.7 1.3 0.7 1.1 0.6 -0.7 0.6 1.1 0.7 0.6 -0.7 0.2 0.9 0.9 1.0 0.9 0.7 1.0 0.8 0.9 0.9 1.0 1.0 0.9
Asthma 0.1 0.2 1.6 0.2 0.1 0.4 1.3 -0.2 0.1 -0.0 0.7 -0.6 0.6 0.1 0.0 -0.0 -0.8 0.5 0.2 0.2 0.3 0.1 0.1 0.2 0.1
Medication: Ibuprofen (e.g. Nurofen) 0.2 0.2 1.2 -0.5 -0.3 -0.8 -1.1 -0.1 -0.1 -0.3 -0.5 0.3 1.1 -0.2 -0.2 -0.2 -0.1 -0.5 -0.5 -0.5 -0.5 -0.2 -0.1 -0.4 -0.2
Medication: Cholesterol lowering 0.3 0.5 2.0 0.9 0.6 -0.1 -0.8 0.6 0.5 0.7 0.0 -0.8 -0.7 0.4 0.5 0.6 0.8 0.7 1.0 1.4 0.7 0.4 0.5 0.9 0.3
Depression (self-reported) 2.4 2.8 5.3 1.7 1.7 1.2 0.4 1.4 2.1 1.7 1.1 -0.7 0.4 2.1 2.1 2.1 1.8 1.7 1.8 1.2 1.8 2.0 2.3 2.0 2.0
Medication: Lansoprazole 0.2 0.2 1.7 -0.6 0.0 0.2 0.4 -0.1 0.0 1.0 0.3 -0.1 0.9 -0.0 0.1 0.0 0.2 0.0 -0.5 -1.3 -0.1 -0.0 -0.5 -0.7 0.0
Prospective memory result 0.3 0.4 3.1 -0.0 -0.6 -0.7 -0.0 -1.0 -0.2 -1.1 -0.8 1.8 0.1 -0.2 -0.2 -0.2 0.4 -0.8 0.1 -0.4 -0.2 -0.2 -0.2 -0.1 -0.3
Lung cancer (father) 2.0 2.4 6.8 -1.4 -1.5 -2.3 -1.5 -2.0 -1.3 -1.7 -1.6 1.6 -2.6 -1.4 -1.4 -1.5 -0.8 -1.8 -1.1 -0.9 -1.3 -1.4 -1.3 -1.2 -1.6
Illnesses of mother 1.0 1.2 2.9 -1.1 -1.2 -0.8 -0.1 -1.2 -1.1 -0.9 -1.1 1.7 0.7 -1.1 -1.2 -1.3 -0.8 -1.3 -1.2 -1.2 -1.2 -1.1 -0.9 -1.1 -1.1
Forced expiratory volume in 1-second (FEV1), Best measure 0.1 0.5 3.3 -1.0 -0.0 1.1 0.9 0.7 -0.2 0.7 0.3 -0.3 -1.8 -0.1 -0.1 -0.1 0.2 -0.2 -0.9 -1.0 -0.6 -0.1 0.1 -0.7 -0.0
Pulse wave Arterial Stiffness index 0.1 0.1 0.3 -0.5 -0.4 -0.3 -0.5 -0.3 -0.2 0.0 -0.1 0.4 -0.2 -0.3 -0.3 -0.3 -0.2 -0.3 -0.5 -0.5 -0.4 -0.3 -0.4 -0.5 -0.2
Impedance of arm (left) 0.4 1.7 4.0 2.0 1.2 1.6 0.7 1.3 1.2 -0.1 1.9 -1.6 0.0 1.2 1.3 1.2 1.6 1.5 1.8 0.9 1.4 1.1 1.0 1.3 1.1
Arm fat mass (right) 0.3 1.4 3.3 -1.3 -1.2 -1.4 -0.2 -1.3 -0.9 -0.6 -0.5 1.6 1.8 -1.0 -0.9 -1.0 -1.3 -1.2 -1.4 -1.6 -1.1 -1.0 -1.1 -1.2 -1.1
Trunk predicted mass 0.5 2.6 5.0 -1.9 -1.7 -2.1 -0.5 -1.8 -1.6 -0.8 -1.6 1.7 -0.3 -1.7 -1.6 -1.6 -2.2 -1.6 -2.0 -1.3 -1.7 -1.6 -1.4 -1.6 -1.6
Standing height 0.2 1.7 3.8 -0.9 -1.4 -1.7 -0.4 -1.4 -1.4 -1.2 -0.9 1.0 -1.9 -1.4 -1.4 -1.3 -1.5 -0.9 -1.3 -1.1 -1.2 -1.4 -1.4 -1.2 -1.4
Length of working week for main job 1.1 1.3 3.4 0.6 1.0 0.6 -0.3 0.1 1.6 1.2 1.0 0.6 1.9 1.6 1.6 1.4 0.5 0.9 0.6 -0.1 1.2 1.6 1.1 0.6 1.7
Exposure to tobacco smoke at home 0.1 0.1 0.7 0.4 0.2 0.3 0.8 -0.0 0.2 0.2 0.4 0.4 0.5 0.1 0.1 0.1 0.3 0.1 0.5 0.4 0.7 0.1 -0.1 0.4 0.1
Breastfed as a baby 0.6 0.7 4.2 0.7 0.6 1.1 1.0 1.0 0.7 0.7 0.0 -0.7 2.0 0.7 0.7 0.8 0.4 0.7 1.0 0.4 0.8 0.7 0.9 0.9 0.6
Tense / ‘highly strung’ 0.2 0.4 2.7 -0.3 -0.6 0.2 1.6 -0.7 -0.4 -0.5 0.0 0.6 0.1 -0.5 -0.4 -0.4 0.2 -0.3 -0.5 -1.3 -0.7 -0.5 -0.2 -0.5 -0.5
Seen doctor (GP) for nerves, anxiety, tension or depression 1.0 1.5 2.6 0.8 1.3 0.6 0.0 1.2 1.5 1.5 0.1 -0.3 1.5 1.6 1.4 1.6 1.3 0.9 1.2 0.2 1.4 1.6 1.5 1.2 1.5
Hair/balding pattern: Pattern 4 0.4 0.9 3.9 -0.0 -1.0 -1.0 0.2 -1.2 -0.5 -1.4 -1.1 2.0 -1.9 -0.7 -0.5 -0.7 -1.4 -1.0 -0.2 -0.2 -0.4 -0.6 -0.7 -0.2 -0.8
Birth weight of first child 1.1 2.0 5.5 1.5 1.1 1.8 2.3 1.0 1.5 1.0 1.8 -0.7 2.0 1.4 1.4 1.4 1.1 1.4 1.1 0.4 1.4 1.4 1.4 1.3 1.4
Peak expiratory flow (PEF) 0.1 0.3 2.4 -1.1 -0.1 0.6 0.5 0.5 -0.1 0.2 0.3 -0.2 -0.9 -0.1 -0.1 -0.2 -0.5 -0.3 -0.9 -1.5 -0.5 -0.1 0.1 -0.6 -0.1
Pulse wave reflection index 0.5 0.6 3.9 -0.5 -0.6 -1.6 -2.0 -1.3 -0.4 -0.4 -0.5 0.9 -1.0 -0.2 -0.5 -0.4 -0.6 -0.5 -0.5 -0.1 -0.5 -0.3 -0.4 -0.5 -0.2
Ever highly irritable/argumentative for 2 days 0.1 0.2 0.9 0.5 -0.3 -0.5 -0.8 -0.2 -0.3 -0.5 -0.2 0.3 -1.0 -0.2 -0.3 -0.1 -0.5 0.0 0.2 0.6 -0.3 -0.2 0.2 0.2 -0.2
Loud music exposure frequency 0.2 0.2 2.2 0.4 -0.1 -0.6 -1.5 0.3 -0.1 0.6 -0.6 -0.4 0.5 -0.1 -0.1 0.0 0.3 0.1 0.2 -0.2 0.2 -0.1 -0.3 0.1 -0.0
Qualifications: O levels/GCSEs or equivalent 3.5 5.6 8.4 2.4 2.5 2.2 1.1 2.9 2.5 1.8 2.2 -2.4 2.5 2.4 2.5 2.5 1.7 2.3 2.5 2.8 2.2 2.5 2.7 2.6 2.3
Mouth/teeth dental problems: Bleeding gums 0.2 0.2 2.3 0.4 0.2 0.3 0.9 0.9 0.2 0.1 0.0 -0.2 1.5 0.1 0.2 0.2 -0.4 0.2 0.4 0.5 0.3 0.1 0.3 0.4 0.1
Blood clot in the leg (DVT) 1.2 1.5 2.6 1.6 1.3 0.3 -0.1 0.2 1.4 1.2 1.2 -1.3 1.6 1.3 1.2 1.3 1.1 1.5 1.4 1.4 1.5 1.3 0.9 1.3 1.2
Medication: Paracetamol 1.1 1.9 3.1 1.7 1.6 0.4 0.0 0.9 1.4 1.4 1.5 -0.7 0.6 1.5 1.3 1.5 1.6 1.6 1.7 1.0 1.6 1.5 1.6 1.7 1.5
Headache pain in last month 0.6 1.0 1.8 0.8 1.1 0.7 0.4 0.3 1.1 1.4 1.3 0.0 -0.0 1.1 1.1 1.2 0.8 1.0 1.0 0.4 1.0 1.1 1.3 1.1 1.2
Medication for cholesterol, blood pressure or diabetes 0.3 0.5 2.5 0.2 0.5 1.2 1.6 0.1 0.9 0.2 0.7 0.4 0.8 0.8 0.8 0.7 -0.2 0.1 0.1 -0.7 0.5 0.8 0.5 0.1 0.9
Glaucoma (self-reported) 0.1 0.1 0.6 -0.7 0.3 -0.5 -0.7 -0.5 -0.1 0.8 0.3 -0.2 -0.0 -0.0 0.0 0.0 -0.3 -0.1 -0.6 -0.0 -0.3 0.0 0.0 -0.3 0.2
Gout (self-reported) 0.7 0.9 4.1 1.3 0.7 0.1 0.7 -0.1 0.9 1.1 0.6 0.5 2.0 0.9 0.8 0.9 0.8 0.8 1.3 0.7 1.4 0.9 0.6 1.2 1.0
Hypothyroidism/myxoedema (self-reported) 1.3 2.5 3.9 1.7 1.5 0.9 1.1 0.5 1.9 1.5 0.9 -0.7 0.6 1.8 1.8 1.9 1.4 2.0 1.9 1.6 2.0 1.8 1.8 1.9 1.8
Medication: Amlodipine 0.7 1.0 2.6 -1.6 -1.0 -0.6 -0.8 0.2 -1.4 -0.6 -0.5 -0.7 0.1 -1.3 -1.3 -1.2 -0.5 -0.3 -1.3 -1.0 -1.4 -1.4 -0.8 -1.0 -1.2
Medication: Ventolin 100micrograms inhaler 0.5 0.6 3.0 0.7 0.6 0.6 0.6 -0.2 0.5 1.2 1.7 -1.0 1.4 0.4 0.6 0.4 0.7 0.9 0.4 1.2 0.5 0.4 0.3 0.5 0.4
Birth weight 0.2 0.5 2.8 0.1 -0.5 -0.5 1.2 -0.8 -0.4 -0.8 -0.8 1.3 1.7 -0.4 -0.6 -0.5 -0.8 -0.9 0.3 -0.4 0.0 -0.4 -0.1 0.3 -0.4
Chronic bronchitis/emphysema (mother) 0.4 0.5 3.6 0.2 0.3 -0.1 -1.4 0.5 -0.4 0.1 0.9 -0.8 -1.9 -0.2 -0.2 0.1 1.0 0.2 0.2 0.8 0.0 -0.2 0.7 0.6 -0.1
High blood pressure (siblings) 0.5 0.8 4.1 -0.9 -0.6 -1.1 -2.0 -0.6 -0.7 -0.4 -0.2 -0.1 -1.1 -0.9 -0.7 -0.7 -0.7 -0.8 -0.7 -0.5 -0.8 -0.8 -1.1 -0.9 -0.8
Forced vital capacity (FVC), Best measure 0.2 0.7 5.9 -1.3 -0.3 0.8 0.0 0.8 -0.4 0.4 0.4 -0.6 -2.4 -0.3 -0.4 -0.3 0.1 -0.2 -1.3 -1.4 -0.9 -0.3 -0.2 -1.0 -0.3
Body fat percentage 0.1 0.5 8.1 -0.2 -0.5 -0.5 0.2 -0.4 -0.0 -0.2 0.1 1.0 2.8 -0.2 -0.0 -0.2 -0.4 -0.4 -0.2 -0.8 -0.1 -0.2 -0.3 -0.2 -0.3
Leg fat percentage (right) 0.1 0.5 5.0 -0.4 -0.6 -0.9 -0.2 -0.7 -0.1 -0.4 -0.8 1.2 2.2 -0.3 -0.2 -0.4 -0.8 -0.6 -0.4 -0.5 -0.2 -0.3 -0.4 -0.3 -0.4
Arm fat-free mass (right) 0.4 2.1 4.1 -1.8 -1.5 -2.0 -0.7 -1.6 -1.4 -0.6 -1.4 1.8 0.4 -1.5 -1.4 -1.5 -1.7 -1.4 -1.8 -1.2 -1.5 -1.5 -1.4 -1.5 -1.4
Exposure to tobacco smoke outside home 1.4 1.9 5.3 1.2 1.4 1.2 0.2 1.7 1.2 1.8 1.9 -1.1 2.3 1.3 1.3 1.4 1.6 1.5 1.1 0.1 1.5 1.3 1.1 1.1 1.3
Comparative body size at age 10 0.1 0.2 0.6 -0.6 -0.1 0.2 -0.0 0.3 -0.4 0.4 -0.1 -0.6 0.2 -0.5 -0.5 -0.5 -0.8 -0.5 -0.4 0.1 -0.5 -0.5 -0.5 -0.4 -0.6
Number of full brothers 1.4 1.8 7.7 -0.9 -0.9 -1.8 -2.6 -1.9 -0.8 -0.7 -1.5 1.8 -2.8 -0.8 -1.0 -0.9 -1.3 -1.4 -0.6 -0.6 -0.6 -0.8 -0.9 -0.7 -0.8
Worry too long after embarrassment 0.1 0.2 2.3 0.7 0.1 0.0 -0.3 -0.2 0.2 0.1 -0.0 -0.4 1.5 0.1 0.2 0.1 0.1 0.2 0.4 0.5 0.2 0.1 -0.5 0.0 -0.0
Seen a psychiatrist for nerves, anxiety, tension or depression 2.9 3.7 7.7 1.3 2.0 2.2 1.4 1.9 2.4 2.8 1.9 -1.0 1.2 2.1 2.3 2.4 2.7 1.9 1.5 0.5 1.9 2.2 1.5 1.4 2.1
Wheeze or whistling in the chest in last year 0.3 0.5 2.0 -0.1 -0.6 -0.9 1.0 -1.4 -0.6 -0.5 0.0 0.1 -1.1 -0.8 -0.7 -0.8 -0.8 0.0 -0.4 -0.3 -0.3 -0.8 -1.0 -0.4 -0.7
Number of children fathered 0.2 0.3 0.7 -0.8 -0.2 0.2 -0.0 0.2 -0.4 -0.4 0.4 -0.6 -0.5 -0.4 -0.2 -0.5 -0.6 -0.4 -0.8 -0.3 -0.8 -0.4 -0.6 -0.8 -0.5
Reason for reducing amount of alcohol drunk: Health precaution 2.5 3.0 4.9 2.1 1.7 1.4 0.1 1.6 1.9 1.7 1.1 -1.5 2.2 1.7 1.8 1.8 2.1 2.1 1.9 1.5 2.0 1.7 1.4 1.7 1.7
Age at first live birth 1.2 2.1 6.2 1.1 1.4 2.5 1.9 2.5 1.1 0.9 1.9 -1.9 1.5 1.0 1.2 1.2 1.6 1.1 1.2 1.4 1.1 1.0 0.9 1.1 0.9
Pulse wave peak to peak time 0.1 0.1 0.5 0.4 0.2 0.2 0.7 0.0 0.1 -0.2 -0.1 -0.1 0.2 0.1 0.1 0.1 -0.1 0.1 0.4 0.3 0.3 0.1 0.3 0.4 0.0
Health satisfaction 0.5 0.7 2.8 -1.2 -0.8 -0.1 1.1 -0.8 -0.5 -0.2 -0.4 0.8 -0.9 -0.7 -0.5 -0.7 -1.0 -0.8 -1.2 -1.7 -0.8 -0.7 -0.6 -1.1 -0.6
Shortness of breath walking on level ground 0.7 0.8 3.2 -0.9 -0.7 -1.3 -0.3 -1.8 -0.8 -0.7 -0.6 0.6 -0.8 -0.9 -0.8 -1.0 -1.4 -0.6 -1.0 -0.3 -0.8 -0.9 -0.9 -0.9 -0.7
Qualifications: College or University degree 0.7 2.2 5.6 0.9 1.5 2.4 2.2 1.8 1.4 1.8 1.1 -1.2 1.7 1.5 1.5 1.7 0.6 1.2 1.0 0.7 1.5 1.5 1.4 1.3 1.7
Eye problems/disorders: None of the above 0.5 0.6 1.6 -0.7 -0.9 0.0 0.3 0.3 -1.0 -0.7 -0.6 0.4 -1.3 -1.0 -1.0 -0.8 -0.1 -0.8 -0.5 -0.8 -0.6 -1.0 -0.9 -0.5 -1.0
Mouth/teeth dental problems: Loose teeth 0.1 0.1 1.2 -0.1 -0.1 -0.1 -0.4 0.3 -0.1 1.1 0.3 -0.3 0.6 -0.3 -0.0 -0.0 0.6 -0.1 -0.3 -0.5 -0.2 -0.2 -0.3 -0.3 -0.3
Emphysema/chronic bronchitis 3.0 3.3 6.4 -1.6 -1.8 -2.3 -0.8 -2.1 -1.9 -1.4 -1.8 2.5 -1.2 -1.9 -2.0 -1.8 -1.1 -2.2 -1.8 -1.6 -1.8 -1.9 -2.1 -1.9 -1.7
Medication for pain relief, constipation, heartburn 1.0 1.7 3.0 -1.4 -1.5 0.3 1.4 -0.5 -1.4 -1.6 -0.7 0.0 -1.6 -1.4 -1.3 -1.4 -1.7 -1.2 -1.4 -1.3 -1.5 -1.4 -1.3 -1.4 -1.5
Neck or shoulder pain in last month 1.1 1.6 3.3 1.8 1.2 0.8 0.3 -0.0 1.4 0.9 0.8 0.5 0.8 1.5 1.5 1.4 1.3 1.1 1.7 1.3 1.7 1.5 1.3 1.6 1.5
Medication: Blood pressure 0.6 1.0 2.1 -1.3 -0.9 -1.4 -1.1 -0.5 -1.3 -0.2 -1.5 0.4 -0.3 -1.2 -1.3 -1.2 -0.3 -0.8 -1.0 -0.1 -1.2 -1.2 -0.9 -0.9 -1.2
Angina (self-reported) 0.8 1.1 4.1 -0.3 -0.8 -1.7 -0.6 -1.8 -1.0 -1.7 -1.7 2.0 -1.0 -0.8 -0.9 -0.7 -0.2 -1.2 0.1 0.2 -0.2 -0.8 -0.5 0.0 -0.7
Migraine (self-reported) 0.1 0.1 1.0 0.3 0.2 0.1 -0.5 0.2 0.1 0.2 0.3 -0.0 1.0 0.2 0.2 0.2 -0.1 0.2 0.5 -0.1 0.5 0.2 0.2 0.5 0.2
Medication: Ibuprofen 0.1 0.2 1.7 -0.4 0.0 -0.4 -1.0 0.1 0.3 0.1 -0.1 -0.1 1.3 0.1 0.2 0.1 -0.0 -0.2 -0.3 -0.5 -0.2 0.2 0.0 -0.3 0.1
Medication: Allopurinol 1.0 1.3 6.5 1.6 0.8 -0.7 0.1 -0.3 1.1 0.9 0.4 0.7 2.6 1.2 1.0 1.2 0.4 0.9 1.5 1.1 1.6 1.2 0.9 1.5 1.3
Medication: Omeprazole 2.9 3.5 5.5 2.0 1.9 1.1 -0.3 1.3 2.2 2.2 1.8 -0.6 1.5 2.2 2.2 2.2 2.4 1.9 2.1 1.9 2.1 2.1 1.7 1.9 2.1
Medication: Seretide 50 evohaler 0.4 0.5 2.9 -0.3 -0.8 -0.9 0.2 -1.7 -0.3 -0.9 -0.7 1.4 0.2 -0.4 -0.4 -0.5 -1.0 -0.8 -0.3 -0.7 -0.3 -0.4 -0.4 -0.4 -0.4
Mean time to correctly identify matches 0.8 1.5 3.2 1.5 1.5 0.6 -0.6 1.4 1.2 0.4 0.4 -1.2 1.4 1.1 1.1 1.1 0.9 1.3 1.7 1.8 1.5 1.2 1.2 1.6 1.1
Heart disease (mother) 0.4 0.5 3.2 -0.2 0.2 -0.0 -1.8 1.0 0.4 0.9 0.9 0.0 -0.4 0.5 0.4 0.7 1.4 0.2 -0.0 -1.0 0.3 0.5 0.6 0.1 0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.9 2.2 4.5 0.8 1.6 0.9 -0.4 0.6 2.1 1.6 2.1 -1.0 1.0 2.0 2.0 1.8 1.5 1.7 0.9 -0.1 1.3 2.0 1.7 1.0 2.1
Whole body fat mass 0.3 1.2 5.8 -1.0 -1.1 -1.3 -0.1 -1.1 -0.8 -0.6 -0.5 1.5 2.4 -0.9 -0.8 -0.9 -1.1 -1.0 -1.1 -1.4 -0.8 -0.9 -0.9 -0.9 -1.0
Leg fat mass (right) 0.3 1.1 3.4 -1.2 -1.1 -1.4 -0.4 -1.1 -0.7 -0.4 -0.8 1.5 1.8 -0.9 -0.8 -0.9 -1.3 -1.1 -1.2 -1.1 -0.9 -0.9 -0.9 -1.0 -0.9
Arm predicted mass (right) 0.4 1.8 3.1 -1.7 -1.4 -1.7 -0.6 -1.3 -1.3 -0.4 -1.2 1.4 0.3 -1.4 -1.3 -1.4 -1.6 -1.3 -1.8 -1.2 -1.5 -1.4 -1.4 -1.5 -1.4
Pulse rate, automated reading 0.1 0.2 0.9 0.1 0.5 0.4 0.3 0.9 0.6 0.5 0.1 -0.4 0.7 0.4 0.4 0.4 0.7 0.2 0.0 -0.3 0.2 0.4 0.3 0.1 0.4
Alcohol intake frequency. 3.3 7.6 14.4 -2.7 -2.9 -2.8 0.2 -3.8 -2.7 -2.7 -2.4 2.7 -2.5 -2.8 -2.6 -2.8 -1.9 -3.0 -2.8 -3.4 -3.0 -2.8 -2.6 -2.9 -2.9
Comparative height size at age 10 0.0 0.1 1.1 0.5 -0.3 -0.6 -1.1 -0.3 -0.2 -0.1 0.4 0.2 0.4 -0.2 -0.1 -0.0 -0.6 -0.1 0.1 -0.0 0.0 -0.2 -0.5 -0.1 -0.2
Number of full sisters 0.2 0.2 1.1 -1.1 -0.3 0.3 -0.2 -0.1 0.2 0.6 0.5 -0.3 0.3 -0.1 0.1 -0.0 -0.1 0.2 -0.9 -0.8 -0.6 -0.1 -0.3 -0.8 -0.1
Suffer from ‘nerves’ 0.1 0.1 1.1 0.0 -0.1 0.1 -0.2 -0.2 0.3 0.1 0.3 0.7 -0.7 0.1 0.4 0.3 0.6 -0.1 -0.1 -1.1 0.0 0.2 -0.2 -0.2 0.0
Overall health rating 1.3 2.8 7.1 -1.7 -1.7 -2.2 -0.9 -2.7 -1.3 -0.6 -1.4 2.6 -1.6 -1.4 -1.4 -1.5 -0.7 -1.6 -1.6 -2.6 -1.2 -1.4 -1.9 -1.7 -1.3
Chest pain or discomfort 0.1 0.1 0.7 -0.1 -0.1 -0.2 0.8 -0.8 -0.3 -0.1 -0.5 0.7 -0.2 -0.1 -0.3 -0.2 0.4 -0.1 0.3 0.2 0.3 -0.2 -0.1 0.3 -0.1
Had major operations 0.3 0.4 1.0 -0.3 -0.6 -0.8 -0.7 -1.0 -0.4 -0.9 -0.6 1.0 0.6 -0.4 -0.5 -0.4 -0.6 -0.9 -0.4 -0.4 -0.6 -0.4 0.2 -0.3 -0.5
Age at last live birth 0.3 0.5 6.0 0.0 0.1 0.5 1.7 0.2 -0.1 -0.3 -0.3 0.5 2.4 0.0 -0.1 -0.0 -0.5 -0.4 0.1 -0.1 0.2 0.0 -0.1 0.1 0.1
Family relationship satisfaction 0.4 0.5 5.4 0.3 -0.1 0.4 1.1 0.3 -0.7 -0.6 -0.6 -0.8 -2.3 -0.6 -0.6 -0.6 -0.5 0.1 -0.1 0.5 -0.4 -0.5 -0.2 -0.1 -0.6
Leg pain on walking 0.7 0.9 2.0 -1.3 -0.8 -1.4 -1.1 -1.1 -0.6 -0.7 -0.9 0.8 1.0 -0.8 -0.6 -0.8 -1.1 -0.9 -1.1 -1.3 -0.8 -0.8 -0.8 -1.1 -0.6
Qualifications: NVQ or HND or HNC or equivalent 0.6 0.7 2.1 1.1 0.5 -0.4 -0.6 -0.2 0.9 0.1 0.2 1.4 0.5 0.9 0.8 0.8 0.5 0.2 1.3 1.2 1.0 0.9 1.0 1.2 0.8
Commuting to job workplace: Car/motor vehicle 0.9 1.0 3.1 -0.7 -1.0 -1.1 0.1 -1.3 -0.6 -0.7 -1.0 1.8 1.6 -0.6 -0.6 -0.6 -1.8 -1.1 -0.8 -1.2 -0.8 -0.6 -0.5 -0.9 -0.5
Illness, injury, bereavement, stress in last 2 years 1.6 2.0 3.5 -1.5 -1.6 -0.0 1.6 -0.8 -1.6 -1.6 -1.3 0.4 1.0 -1.7 -1.6 -1.8 -0.9 -1.3 -1.5 -1.3 -1.7 -1.7 -1.5 -1.4 -1.9
Medication: Aspirin 0.2 0.3 1.8 -0.2 -0.0 -0.9 -1.3 -0.7 -0.4 0.1 -0.8 0.7 -1.0 -0.3 -0.4 -0.3 -0.0 -0.6 -0.2 0.4 -0.1 -0.3 -0.4 -0.1 -0.2
Supplements: Vitamin C 0.2 0.2 2.4 -0.0 0.2 -0.2 -1.6 0.7 -0.3 0.4 0.2 -0.6 -0.5 -0.1 -0.2 -0.0 0.1 0.1 0.1 -0.1 -0.1 -0.1 0.1 0.2 -0.1
Knee pain experienced in last month 0.4 0.6 1.8 -1.0 -0.6 -1.0 0.3 -1.3 -0.4 0.4 -1.1 1.4 0.5 -0.4 -0.4 -0.4 0.1 -0.8 -0.9 -1.3 -0.6 -0.4 -0.8 -0.9 -0.3
Hypertension (Self-reported) 0.6 1.6 3.1 -1.8 -1.3 -1.3 -0.2 -1.4 -1.4 -1.0 -1.6 0.9 -1.0 -1.4 -1.4 -1.3 -1.1 -1.4 -1.4 -0.7 -1.5 -1.4 -1.1 -1.3 -1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.7 0.8 3.4 0.6 1.1 -0.3 -0.7 0.8 0.8 0.9 1.1 -1.1 1.8 0.9 0.9 1.0 0.2 1.1 0.6 0.9 0.7 0.9 0.9 0.6 1.0
Illnesses of father: Heart disease 0.1 0.2 1.6 0.1 -0.3 -0.9 -0.9 -0.3 -0.1 0.0 -0.3 0.3 1.3 -0.1 -0.0 -0.1 -0.1 -0.0 -0.0 -0.2 -0.0 -0.1 0.0 0.0 -0.1
Illnesses of siblings: Diabetes 0.2 0.2 1.1 0.1 0.4 -0.8 -0.5 -0.2 0.2 0.1 -0.1 -1.0 1.1 0.2 0.2 0.0 -0.1 0.5 0.5 -0.2 0.5 0.2 0.0 0.4 0.2
Smoking status: Previous 0.1 0.1 0.9 0.3 -0.1 0.4 0.6 0.5 0.0 -0.2 0.3 0.7 -1.0 -0.1 0.1 0.0 -0.0 -0.0 -0.1 0.5 -0.2 -0.0 -0.1 -0.1 -0.1
Forced expiratory volume in 1-second (FEV1), predicted 0.4 0.8 3.4 -1.0 -0.6 -1.4 -1.9 -0.6 -0.8 0.2 -0.3 1.3 -1.5 -0.5 -0.6 -0.5 -0.5 -0.6 -1.0 -0.8 -0.6 -0.5 -0.8 -0.9 -0.4
Whole body fat-free mass 0.4 2.0 4.1 -1.6 -1.5 -2.0 -0.4 -1.8 -1.4 -0.5 -1.1 1.7 0.1 -1.4 -1.3 -1.4 -1.8 -1.4 -1.8 -1.3 -1.4 -1.4 -1.3 -1.5 -1.3
Leg fat-free mass (right) 0.2 1.2 3.3 -1.4 -1.1 -1.6 0.1 -1.8 -0.9 -0.1 -0.3 1.5 0.5 -1.0 -0.8 -0.9 -1.2 -1.0 -1.5 -1.4 -1.1 -0.9 -1.0 -1.3 -0.9
Arm fat percentage (left) 0.1 0.4 6.8 -0.2 -0.4 -0.2 0.6 -0.4 0.1 -0.1 0.4 0.9 2.6 -0.1 0.1 -0.0 -0.3 -0.2 -0.2 -0.7 -0.0 -0.1 -0.1 -0.2 -0.1
Average weekly red wine intake 13.4 19.8 27.5 5.2 4.7 3.8 -0.4 4.1 4.5 3.9 4.5 -3.2 2.9 4.6 4.7 4.9 4.6 4.7 5.0 5.2 5.1 4.7 4.7 5.1 4.7
Handedness (chirality/laterality): Left-handed 1.5 1.9 3.8 -1.7 -1.2 -1.4 -0.0 -0.5 -1.5 -1.0 -2.0 -0.0 0.3 -1.4 -1.6 -1.5 -1.3 -1.4 -1.7 -1.8 -1.5 -1.4 -1.5 -1.6 -1.3
Mood swings 0.3 0.6 4.8 0.4 0.5 0.1 -1.0 0.5 0.5 1.0 0.7 0.2 -2.2 0.5 0.6 0.7 1.6 0.6 0.4 -0.2 0.5 0.5 0.2 0.2 0.5
Loneliness, isolation 0.3 0.4 3.7 0.5 0.7 0.3 0.9 0.2 0.5 0.6 0.3 -0.6 -1.9 0.5 0.5 0.5 0.4 0.6 0.5 0.5 0.4 0.5 0.2 0.4 0.4
Long-standing illness, disability or infirmity 0.2 0.3 0.8 0.9 0.3 -0.4 -0.8 -0.5 0.7 0.8 0.1 0.2 -0.1 0.6 0.7 0.6 0.2 0.7 0.8 0.1 0.9 0.5 0.3 0.7 0.6
Ever had bowel cancer screening 0.5 0.5 1.9 0.8 0.5 0.8 -0.5 0.8 0.4 0.6 1.4 -0.8 1.4 0.3 0.5 0.4 1.3 0.9 0.4 0.6 0.6 0.3 -0.3 0.1 0.4
Diabetes diagnosed by doctor 0.1 0.2 3.1 0.2 0.1 0.1 0.1 0.4 -0.2 0.2 -0.4 -0.7 -1.8 -0.2 -0.2 -0.2 -0.6 0.3 0.1 0.8 -0.0 -0.2 -0.3 0.0 -0.3
Ever had stillbirth, spontaneous miscarriage or termination 0.2 0.2 1.1 -0.4 -0.5 -0.4 0.6 0.2 -0.6 -0.0 -0.4 -0.0 0.4 -0.5 -0.7 -0.5 -1.0 0.0 -0.4 -0.7 -0.4 -0.6 -0.3 -0.3 -0.5
Friendships satisfaction 0.2 0.3 1.3 0.4 0.4 0.7 1.1 1.1 -0.0 0.2 -0.2 -1.0 -1.0 0.1 0.2 0.1 -0.3 0.5 0.4 0.6 0.3 0.1 0.0 0.3 0.0
Qualifications: nursing, teaching 0.5 0.7 2.0 1.0 0.7 0.5 0.9 0.4 0.8 1.0 0.7 -0.5 0.7 0.8 0.9 1.0 0.3 0.7 1.1 1.4 0.9 0.8 0.9 1.0 0.8
Commuting to job workplace: Walk 1.7 1.8 4.5 1.5 1.4 1.9 1.0 1.5 1.1 1.1 1.4 -2.1 -0.7 1.1 1.2 1.2 1.2 1.4 1.2 1.5 1.2 1.1 1.4 1.4 1.1
Eye problems/disorders: Cataract 1.1 1.2 2.9 0.7 1.2 0.5 -0.6 0.9 1.2 1.3 1.0 -1.7 1.6 1.1 1.3 1.1 1.1 1.4 0.8 0.8 1.0 1.1 1.0 0.8 1.2
Mouth/teeth dental problems: Mouth ulcers 4.3 6.8 10.3 2.6 2.8 1.6 -1.5 2.2 3.0 3.0 2.5 -2.1 2.0 2.9 3.0 3.0 3.2 2.7 2.6 2.0 2.7 2.9 2.7 2.6 2.8
Medication for cholesterol 0.1 0.1 0.5 0.5 -0.4 0.3 0.4 -0.2 -0.2 -0.5 -0.1 0.1 0.1 -0.2 -0.2 -0.3 0.7 -0.1 0.2 -0.0 -0.2 -0.2 -0.1 0.1 -0.5
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.2 0.3 0.8 0.9 0.2 -0.8 0.8 -0.6 0.4 0.6 -0.2 0.8 0.6 0.5 0.4 0.5 -0.3 0.5 0.2 0.3 0.4 0.4 0.2 0.4 0.6
Back pain experienced in last month 0.3 0.4 2.3 -0.3 -0.6 -1.0 -0.4 -0.8 -0.6 -0.7 -0.6 1.5 0.7 -0.4 -0.5 -0.5 0.3 -0.4 -0.1 -0.7 -0.2 -0.5 -0.4 -0.2 -0.5
Mineral and other dietary supplements 0.9 1.2 2.1 0.6 1.2 1.2 1.1 0.7 1.3 1.1 1.2 -0.4 -0.0 1.4 1.4 1.3 0.3 0.9 1.0 0.7 1.1 1.4 1.5 1.0 1.4
Breast cancer (self-reported) 0.5 0.6 3.8 0.5 0.7 1.1 0.7 2.0 0.5 1.0 0.5 -1.1 0.5 0.6 0.5 0.4 0.7 0.7 0.3 0.6 0.6 0.6 0.8 0.5 0.7
Asthma (self-reported) 0.1 0.3 2.5 0.4 0.2 0.6 1.6 -0.0 0.3 0.0 1.0 -0.6 0.4 0.3 0.2 0.2 -0.7 0.6 0.4 0.3 0.5 0.2 0.3 0.4 0.2
Osteoporosis (self-reported) 0.4 0.4 2.2 0.8 0.7 -0.6 -1.5 0.1 0.4 0.1 0.1 0.1 -1.4 0.6 0.4 0.5 0.4 0.4 0.7 0.6 0.6 0.6 0.7 0.8 0.6
Osteoarthritis (self-reported) 0.9 1.2 4.6 0.8 1.2 0.3 -0.4 0.8 1.2 2.1 1.3 -0.8 0.5 1.2 1.2 1.3 1.2 1.2 0.8 0.1 1.0 1.1 1.1 0.9 1.2
Medication: Aspirin 0.4 0.5 1.9 -0.3 -0.3 -1.0 -0.9 -1.0 -0.7 -0.4 -1.1 0.7 -1.4 -0.6 -0.7 -0.6 -0.2 -0.8 -0.3 0.4 -0.4 -0.6 -0.6 -0.3 -0.6
Medication: Gliclazide 0.2 0.2 0.9 0.1 -0.1 -0.2 0.2 -0.7 -0.6 -0.3 -0.5 -0.2 -0.2 -0.5 -0.6 -0.5 -0.4 -0.1 -0.1 0.3 -0.0 -0.5 -0.9 -0.3 -0.5
Illnesses of father: None of the above (group 1) 1.3 1.6 3.8 -1.9 -0.9 -1.7 -1.2 -1.6 -1.0 -0.1 -1.3 1.6 -1.5 -1.0 -1.1 -1.0 -0.4 -1.9 -1.5 -0.9 -1.3 -1.0 -1.2 -1.4 -0.9
Smoking status: Current 0.5 0.9 2.3 0.7 1.2 0.0 -1.2 0.4 0.8 1.1 0.4 -0.6 -0.3 1.0 0.8 0.9 1.5 0.8 1.2 0.8 1.1 1.0 1.1 1.2 1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.4 1.1 0.3 0.7 1.0 0.6 0.7 0.6 1.0 -0.1 -0.9 0.7 0.5 0.5 0.5 0.6 0.1 0.4 0.8 0.4 0.5 0.7 0.5 0.5
Whole body water mass 0.4 2.0 4.1 -1.7 -1.5 -2.0 -0.4 -1.9 -1.4 -0.5 -1.1 1.7 0.1 -1.4 -1.3 -1.4 -1.8 -1.4 -1.8 -1.3 -1.4 -1.4 -1.3 -1.5 -1.3
Leg predicted mass (right) 0.2 1.1 3.2 -1.3 -1.0 -1.5 0.1 -1.8 -0.9 -0.0 -0.3 1.4 0.6 -0.9 -0.8 -0.8 -1.1 -0.9 -1.4 -1.3 -1.0 -0.8 -1.0 -1.2 -0.8
Arm fat mass (left) 0.2 0.7 4.7 -0.8 -0.8 -1.0 -0.1 -0.9 -0.5 -0.3 -0.1 1.3 2.2 -0.6 -0.5 -0.6 -0.9 -0.7 -0.9 -1.1 -0.6 -0.6 -0.6 -0.7 -0.6
Number of self-reported non-cancer illnesses 0.6 1.0 2.3 1.1 1.0 0.4 0.2 0.8 1.0 0.9 0.4 -0.5 -0.2 1.1 1.1 1.2 0.6 1.2 1.4 0.7 1.4 1.1 1.3 1.5 1.1
Average weekly champagne plus white wine intake 0.2 0.3 1.4 -1.1 -0.4 -0.1 0.8 -0.6 -0.2 0.6 -0.1 0.3 -0.1 -0.2 -0.2 -0.2 -0.2 -0.3 -1.2 -1.1 -0.7 -0.1 -0.3 -1.0 -0.0
Miserableness 0.7 1.2 4.8 -0.9 -1.1 -1.5 -1.3 -0.6 -1.0 -0.1 -0.5 1.0 -2.2 -1.1 -0.9 -0.9 -0.3 -0.9 -1.1 -1.3 -1.0 -1.1 -1.5 -1.3 -1.1
Guilty feelings 0.1 0.2 0.8 -0.4 -0.2 -0.7 -0.9 -0.5 -0.5 0.4 0.1 0.5 -0.4 -0.4 -0.4 -0.4 -0.6 -0.5 -0.5 -0.1 -0.3 -0.5 -0.5 -0.5 -0.3
Wears glasses or contact lenses 3.1 3.6 6.0 2.3 1.9 1.9 -0.2 2.1 1.8 1.5 1.3 -1.4 2.4 1.9 1.8 1.9 1.1 1.7 2.4 2.2 2.3 1.9 1.9 2.2 1.8
Ever taken oral contraceptive pill 3.2 3.5 5.4 -2.3 -2.3 -1.8 -0.5 -1.7 -2.0 -1.1 -1.8 1.9 -1.5 -2.0 -2.0 -1.9 -1.8 -1.9 -2.1 -1.9 -2.0 -2.0 -1.9 -2.0 -2.0
Hearing aid user 0.6 0.6 2.7 0.5 0.6 -0.2 -1.4 -0.0 0.7 1.2 0.7 0.0 1.6 0.7 0.7 0.7 0.5 0.5 0.6 0.9 0.7 0.8 0.9 0.7 0.7
Mother’s age at death 0.1 0.1 0.8 0.2 -0.1 0.6 0.9 0.5 0.2 -0.0 0.3 -0.2 -0.4 0.1 0.3 0.3 0.2 0.1 0.2 -0.6 0.1 0.1 0.1 0.1 0.0
Financial situation satisfaction 1.9 2.4 4.8 1.2 1.7 1.7 0.1 2.2 1.5 1.7 2.0 -1.7 0.3 1.5 1.4 1.6 1.5 1.6 1.3 1.4 1.6 1.5 1.8 1.5 1.6
Tinnitus: Yes, now most or all of the time 3.2 3.7 7.1 1.2 2.3 1.2 -1.6 2.0 2.0 2.7 2.0 -2.6 0.5 2.0 2.1 2.1 2.4 2.3 1.3 1.9 1.7 2.0 1.7 1.4 2.0
Commuting to job workplace: Public transport 0.6 0.7 7.1 -0.7 -0.6 0.3 0.5 0.1 -0.8 -0.8 -0.0 -0.5 -2.7 -0.8 -0.8 -0.7 -0.1 -0.4 -0.5 -0.6 -0.7 -0.8 -0.5 -0.5 -0.8
Eye problems/disorders: Glaucoma 1.9 2.2 5.1 0.8 2.0 0.7 -0.4 0.7 1.7 2.3 1.9 -1.4 1.2 1.7 1.8 1.8 1.1 1.5 0.8 1.8 1.1 1.8 1.7 1.2 1.8
Medication: Blood pressure 0.7 1.4 2.6 -1.6 -1.1 -0.7 0.6 -0.7 -1.2 -1.3 -1.1 0.8 -1.5 -1.2 -1.1 -1.1 -1.5 -1.1 -1.4 -1.3 -1.3 -1.2 -1.1 -1.3 -1.0
Pain type(s) experienced in last month: Hip pain 0.7 0.9 3.5 -0.3 -1.0 -1.2 -0.0 -1.6 -0.6 -1.7 -1.4 1.9 -0.6 -0.7 -0.7 -0.8 -1.4 -1.0 -0.2 -0.7 -0.5 -0.7 -0.3 -0.2 -0.7
Supplements: Fish oil (including cod liver oil) 0.7 0.9 2.4 -0.5 -0.9 -1.6 -1.3 -0.8 -1.0 -0.6 -1.1 0.6 0.4 -1.1 -1.1 -0.9 0.2 -0.7 -1.0 -0.1 -1.1 -1.1 -1.1 -0.9 -1.1
High cholesterol (Self-reported) 0.2 0.4 0.9 0.6 0.7 -0.3 -0.9 0.5 0.5 0.5 0.6 -1.0 -0.4 0.5 0.6 0.6 0.4 0.9 0.7 0.7 0.6 0.4 0.7 0.7 0.5
Medication: Bendroflumethiazide 0.1 0.1 0.5 -0.2 0.3 -0.0 -0.6 0.1 0.4 0.2 0.2 -0.1 0.7 0.4 0.3 0.5 0.6 0.3 -0.0 0.1 0.2 0.4 0.5 0.2 0.5
Medication: Paracetamol 1.0 1.5 2.7 1.7 1.2 -0.2 0.1 0.3 1.3 1.3 1.2 0.0 1.4 1.4 1.3 1.4 1.3 1.5 1.5 0.7 1.6 1.4 1.2 1.5 1.4
Medication: Lisinopril 0.1 0.2 2.2 0.1 -0.2 0.3 -0.1 0.1 -0.5 0.4 -0.0 0.6 -1.5 -0.4 -0.4 -0.3 -0.1 -0.3 -0.0 0.0 -0.1 -0.4 -0.5 -0.1 -0.4
Medication: Atorvastatin 1.3 1.6 4.5 -0.7 -1.4 -1.7 -0.9 -1.2 -1.3 -1.6 -2.1 2.1 -0.7 -1.2 -1.4 -1.2 -1.3 -1.7 -0.5 -0.7 -0.8 -1.2 -1.0 -0.6 -1.2
Illnesses of father: High blood pressure 0.3 0.4 1.7 0.8 0.3 0.9 -0.0 1.3 0.2 -0.6 0.6 -0.8 -0.9 0.3 0.4 0.4 0.1 0.6 1.0 0.6 0.6 0.3 0.5 0.8 0.2
Alcohol drinker status: Never 1.5 1.8 4.6 -1.6 -1.4 -0.3 2.1 -2.1 -1.3 -0.8 -0.8 1.3 0.1 -1.4 -1.2 -1.3 -0.5 -1.6 -1.4 -1.7 -1.4 -1.4 -1.2 -1.5 -1.3
Ever smoked 0.2 0.4 5.4 0.4 0.0 -0.4 -0.5 0.5 -0.2 -0.1 -0.4 0.6 -2.3 -0.2 -0.1 -0.2 0.0 -0.2 0.2 0.9 -0.2 -0.2 -0.2 0.1 -0.3
Basal metabolic rate 0.4 2.2 4.4 -1.6 -1.6 -2.1 -0.4 -1.9 -1.4 -0.6 -1.1 2.0 0.5 -1.4 -1.4 -1.4 -1.8 -1.4 -1.8 -1.4 -1.4 -1.4 -1.4 -1.5 -1.4
Leg fat percentage (left) 0.2 0.7 4.9 -0.7 -0.7 -1.0 -0.2 -0.6 -0.2 -0.3 -0.9 1.3 2.2 -0.5 -0.3 -0.5 -1.0 -0.8 -0.6 -0.7 -0.4 -0.4 -0.6 -0.5 -0.6
Arm fat-free mass (left) 0.5 2.4 4.6 -1.8 -1.7 -2.1 -0.4 -1.7 -1.5 -0.6 -1.6 2.0 0.6 -1.5 -1.5 -1.5 -1.9 -1.5 -1.9 -1.4 -1.6 -1.5 -1.4 -1.6 -1.5
Number of operations (self-reported) 0.3 0.4 2.5 -1.0 -0.5 -0.6 -0.2 -0.1 -0.2 0.4 -0.5 1.5 1.0 -0.1 -0.2 -0.1 0.0 -0.7 -0.9 -1.6 -0.3 -0.1 -0.2 -0.7 0.1
Average weekly beer plus cider intake 2.9 4.2 6.6 -1.8 -2.3 -2.3 -1.0 -1.5 -2.3 -2.6 -2.1 2.4 -1.0 -2.1 -2.2 -2.4 -2.2 -2.4 -1.9 -2.0 -2.0 -2.1 -1.8 -1.8 -2.1
Irritability 3.5 5.9 9.2 2.9 2.4 3.0 2.2 3.0 2.3 2.6 2.2 -1.8 -0.4 2.3 2.4 2.5 2.4 2.9 2.6 1.9 2.6 2.3 2.3 2.6 2.3
Risk taking 0.3 0.4 2.0 0.7 0.7 -0.6 -1.4 0.6 0.3 0.4 -0.0 -1.2 0.0 0.4 0.2 0.3 0.6 0.4 0.5 1.3 0.5 0.3 0.2 0.5 0.4
Ever had prostate specific antigen (PSA) test 0.5 0.6 9.5 -0.0 -0.6 -0.5 -0.8 -0.4 -0.2 0.1 -0.2 0.5 3.1 -0.4 -0.3 -0.2 -0.0 -0.6 -0.2 -0.3 -0.1 -0.4 -0.6 -0.2 -0.4
Fractured/broken bones in last 5 years 0.7 0.9 2.9 0.8 1.1 1.3 0.5 0.7 0.8 0.4 1.2 -0.7 -1.7 0.9 0.9 0.9 0.9 1.0 0.9 0.5 1.0 0.9 1.0 0.9 1.0
Age started oral contraceptive pill 0.5 0.7 2.8 0.8 1.0 0.6 -0.9 1.2 0.6 0.6 0.9 -1.7 0.6 0.7 0.7 0.6 0.3 0.9 0.8 1.0 0.6 0.6 0.5 0.6 0.7
Diastolic blood pressure, automated reading 0.2 0.6 3.1 -1.8 -0.5 -0.7 -0.3 -0.1 -0.3 0.1 -0.3 -0.6 -0.2 -0.5 -0.4 -0.5 -1.0 -0.4 -1.4 -1.4 -1.1 -0.5 -0.6 -1.2 -0.5
Ever depressed for a whole week 0.9 1.2 4.2 -0.2 -0.7 -1.0 0.1 -2.0 -1.0 -2.1 -1.1 2.0 -1.8 -0.6 -0.9 -0.9 -1.4 -1.1 -0.2 -0.3 -0.4 -0.7 -0.1 -0.0 -0.6
Unable to work because of sickness or disability 0.8 1.0 2.9 0.8 1.1 0.3 -1.4 -0.1 1.1 0.8 0.5 0.4 -0.2 1.1 1.1 1.1 1.7 0.5 1.2 1.1 1.4 1.1 1.0 1.2 1.2
Commuting to job workplace: Cycle 3.0 3.7 7.8 1.6 2.0 2.8 2.0 2.1 1.8 1.9 2.3 -2.7 -0.7 1.8 1.8 1.9 2.2 2.2 1.5 1.5 1.6 1.8 1.7 1.6 1.8
Myopia 0.5 0.7 2.1 0.9 0.8 1.4 0.8 0.9 0.8 0.8 0.7 -0.3 -0.6 0.8 0.8 0.9 1.3 0.6 1.0 0.7 1.0 0.8 0.5 0.9 0.7
Vascular/heart problems diagnosed by doctor 0.8 2.3 4.1 1.7 1.5 1.5 0.3 1.6 1.9 1.5 2.0 -1.2 1.1 1.8 1.8 1.7 0.9 1.7 1.4 0.5 1.6 1.8 1.4 1.3 1.7
Cholesterol lowering medication 1.2 1.7 2.9 1.2 1.7 0.3 -0.8 0.9 1.4 1.3 1.1 -1.1 0.6 1.5 1.5 1.5 0.7 1.5 1.3 1.5 1.6 1.5 1.5 1.5 1.6
Medication: Omeprazole (e.g. Zanprol) 4.4 5.4 8.8 2.3 2.4 1.3 -0.2 1.8 2.6 3.0 2.3 -0.8 2.5 2.7 2.7 2.7 2.7 2.3 2.4 2.0 2.6 2.7 2.1 2.2 2.7
Pain experienced in last month 0.3 0.6 6.5 -0.2 0.3 1.1 0.8 1.2 0.1 0.3 0.8 -2.5 -0.8 -0.0 0.0 0.1 -0.3 0.7 -0.2 0.5 -0.2 0.0 -0.1 -0.2 -0.1
Supplements: Calcium 0.3 0.3 0.7 -0.3 -0.7 0.0 0.3 -0.6 -0.8 -0.6 -0.6 0.6 0.2 -0.8 -0.8 -0.7 -0.5 -0.6 -0.4 -0.3 -0.4 -0.7 -0.9 -0.4 -0.7
Basal cell carcinoma (self-reported) 0.2 0.2 2.0 0.4 0.1 -0.3 0.1 -1.4 0.5 0.2 -0.4 0.6 -0.2 0.4 0.3 0.4 0.0 -0.2 0.4 0.1 0.3 0.4 0.2 0.1 0.5
Heart attack/myocardial infarction (self-reported) 0.9 1.2 2.6 -0.7 -1.1 -1.1 -0.1 -0.8 -1.6 -1.4 -0.8 0.3 -0.4 -1.6 -1.5 -1.5 -0.8 -1.0 -0.8 -0.5 -1.1 -1.6 -1.2 -0.8 -1.6
Deep venous thrombosis (DVT) (self-reported) 0.9 1.2 2.3 1.5 1.1 0.1 0.0 -0.3 1.3 1.1 1.0 -1.0 1.4 1.1 1.1 1.1 1.1 1.3 1.3 1.4 1.3 1.1 0.6 1.2 1.1
Heart disease (siblings) 0.5 0.6 2.2 -0.8 -0.6 -1.5 -1.5 -0.5 -0.4 -0.7 -0.8 0.1 -0.3 -0.7 -0.6 -0.5 -0.6 -0.5 -0.5 -1.0 -0.7 -0.6 -0.7 -0.6 -0.7
Alcohol drinker status: Previous 0.7 0.7 4.0 -0.3 -0.5 -1.5 -1.9 -0.5 -0.7 -1.2 -0.3 0.0 -2.0 -0.7 -0.6 -0.7 -0.7 -0.3 -0.5 -0.5 -0.6 -0.6 -0.5 -0.5 -0.7
Pack years of smoking 0.7 1.1 2.0 1.0 1.3 -0.3 -0.9 -0.0 1.4 0.8 0.5 -0.8 0.7 1.4 1.2 1.2 0.3 1.1 1.1 1.2 1.1 1.4 1.1 1.1 1.3
Impedance of whole body 0.3 1.5 3.8 2.0 1.0 1.5 0.3 1.7 1.1 -0.1 1.4 -1.5 -0.2 1.0 1.1 1.1 1.5 1.4 1.7 1.0 1.3 1.0 0.8 1.3 0.9
Leg fat mass (left) 0.3 1.3 3.2 -1.3 -1.1 -1.6 -0.5 -1.1 -0.8 -0.4 -0.9 1.6 1.8 -1.0 -0.8 -1.0 -1.4 -1.2 -1.3 -1.2 -1.0 -1.0 -1.0 -1.1 -1.0
Arm predicted mass (left) 0.5 2.4 4.6 -1.8 -1.7 -2.1 -0.4 -1.9 -1.5 -0.6 -1.4 2.0 0.5 -1.6 -1.5 -1.5 -1.8 -1.6 -1.9 -1.3 -1.6 -1.5 -1.4 -1.6 -1.5