[Hub]/) : Traits : Comparative body size at age 10 : ← →

chr12:48,605,088-51,365,312

Best TWAS P=9.46e-58 · Best GWAS P=4.07e-82 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
39	GTEx	Testis	FAIM2	0.27	0.09	lasso	5	0.06	9.3e-04	16.92	-16.0	9.5e-58	-0.77	0.05	0.84	TRUE
18	GTEx	Breast Mammary Tissue (Female)	CERS5	0.09	0.03	lasso	3	0.05	1.8e-02	1.70	-12.7	9.7e-37	-0.53	0.05	0.22	TRUE
36	GTEx	Spleen	LMBR1L	0.30	0.30	enet	11	0.30	2.4e-08	7.99	-8.8	1.9e-18	-0.09	0.01	0.98	TRUE
1	CommonMind	Brain Pre-frontal Cortex	FAIM2	0.09	0.00	bslmm	336	0.03	3.7e-04	1.02	8.7	3.3e-18	0.52	0.06	0.79	TRUE
52	The Cancer Genome Atlas	Breast Invasive Carcinoma	FAIM2	0.02	0.00	blup	71	0.01	8.5e-03	1.02	-8.3	6.6e-17	-0.36	0.16	0.12	TRUE
56	The Cancer Genome Atlas	Prostate Adenocarcinoma	TUBA1C	0.04	0.02	blup	37	0.04	2.3e-05	6.88	8.1	8.6e-16	0.19	0.02	0.96	TRUE
28	GTEx	Nerve Tibial	LMBR1L	0.08	0.04	lasso	4	0.06	3.1e-05	6.19	-7.8	6.1e-15	-0.05	0.04	0.95	TRUE
12	GTEx	Artery Tibial	LMBR1L	0.07	0.04	enet	13	0.03	1.7e-03	8.11	-7.6	2.4e-14	-0.02	0.02	0.98	TRUE
25	GTEx	Esophagus Muscularis	RP11-386G11.10	0.10	0.11	lasso	7	0.10	1.0e-06	7.05	-7.6	3.9e-14	-0.04	0.06	0.94	TRUE
16	GTEx	Brain Cortex	CERS5	0.26	0.09	enet	30	0.11	5.9e-04	1.41	-7.6	4.2e-14	-0.28	0.29	0.04	TRUE
26	GTEx	Lung	LMBR1L	0.05	0.02	lasso	2	0.00	1.5e-01	6.59	-7.4	1.1e-13	-0.07	0.04	0.80	TRUE
37	GTEx	Testis	SMARCD1	0.22	0.10	enet	22	0.10	2.6e-05	-5.22	7.0	2.2e-12	0.09	0.74	0.03	TRUE
58	The Cancer Genome Atlas	Thyroid Carcinoma	FAIM2	0.14	0.04	blup	69	0.07	1.2e-07	-1.28	6.7	2.2e-11	0.29	0.99	0.00	TRUE
8	GTEx	Artery Aorta	CCDC65	0.19	0.08	enet	7	0.11	1.9e-06	2.77	5.6	2.5e-08	0.14	0.91	0.06	TRUE
21	GTEx	Esophagus Mucosa	CERS5	0.08	0.00	enet	23	0.01	6.4e-02	1.95	5.4	6.0e-08	0.23	0.25	0.28	TRUE
23	GTEx	Esophagus Mucosa	RP11-386G11.10	0.10	0.02	enet	23	0.05	2.0e-04	7.05	-5.4	7.0e-08	0.05	0.14	0.72	TRUE
19	GTEx	Cells Transformed fibroblasts	LIMA1	0.17	0.01	lasso	6	0.02	8.8e-03	0.65	5.3	1.1e-07	0.21	0.14	0.08	TRUE
34	GTEx	Skin Sun Exposed Lower leg	RP11-386G11.10	0.08	0.00	enet	18	0.01	3.1e-02	7.25	-5.2	2.7e-07	-0.09	0.02	0.55	TRUE
3	CommonMind	Brain Pre-frontal Cortex	TUBA1A	0.08	0.06	lasso	4	0.06	1.8e-07	8.02	-8.5	1.5e-17	-0.05	0.04	0.96	FALSE
51	YFS	Blood	TUBA1B	0.02	0.02	lasso	8	0.02	2.7e-08	7.05	8.4	4.9e-17	0.09	0.22	0.78	FALSE
38	GTEx	Testis	TUBA1B	0.21	0.28	lasso	9	0.26	7.0e-12	8.11	-8.1	5.8e-16	-0.03	0.01	0.99	FALSE
10	GTEx	Artery Aorta	RP11-302B13.5	0.13	0.07	lasso	6	0.06	2.0e-04	7.85	-8.1	6.2e-16	-0.03	0.01	0.96	FALSE
32	GTEx	Skin Sun Exposed Lower leg	LMBR1L	0.15	0.10	lasso	3	0.09	3.1e-08	7.93	-8.1	7.4e-16	-0.03	0.01	0.99	FALSE
46	GTEx	Thyroid	LMBR1L	0.12	0.10	lasso	3	0.10	6.4e-08	7.93	-8.1	8.3e-16	-0.03	0.01	0.99	FALSE
22	GTEx	Esophagus Mucosa	LMBR1L	0.07	0.03	lasso	5	0.04	1.8e-03	6.59	-8.0	9.1e-16	-0.09	0.02	0.94	FALSE
48	METSIM	Adipose	LMBR1L	0.05	0.03	blup	303	0.03	5.2e-06	7.93	-8.0	1.0e-15	-0.03	0.01	0.99	FALSE
43	GTEx	Testis	RP11-386G11.10	0.25	0.33	lasso	9	0.32	1.3e-14	8.11	-8.0	1.7e-15	-0.02	0.01	0.99	FALSE
29	GTEx	Nerve Tibial	RP11-386G11.10	0.07	0.05	lasso	2	0.03	1.8e-03	7.89	-7.9	2.9e-15	-0.02	0.01	0.97	FALSE
15	GTEx	Brain Cerebellum	LMBR1L	0.18	0.15	lasso	1	0.12	1.9e-04	7.89	-7.9	3.0e-15	-0.02	0.01	0.95	FALSE
7	GTEx	Adipose Visceral Omentum	LMBR1L	0.09	0.03	lasso	6	0.01	7.4e-02	7.99	-7.8	4.2e-15	-0.03	0.03	0.90	FALSE
6	GTEx	Adipose Subcutaneous	LMBR1L	0.12	0.09	lasso	6	0.08	1.9e-07	7.89	-7.8	5.8e-15	-0.05	0.01	0.99	FALSE
2	CommonMind	Brain Pre-frontal Cortex	RHEBL1	0.03	0.01	blup	315	0.02	4.4e-03	6.23	7.8	7.9e-15	0.15	0.09	0.62	FALSE
24	GTEx	Esophagus Muscularis	TUBA1B	0.08	0.04	lasso	7	0.06	1.9e-04	7.05	-7.8	8.3e-15	-0.05	0.04	0.89	FALSE
4	CommonMind	Brain Pre-frontal Cortex	TUBA1B	0.08	0.06	lasso	7	0.06	4.6e-08	7.05	-7.7	1.1e-14	-0.04	0.08	0.92	FALSE
49	NTR	Blood	BCDIN3D	0.02	0.00	blup	331	0.00	8.2e-03	3.29	-7.7	1.4e-14	-0.41	0.03	0.18	FALSE
41	GTEx	Testis	LMBR1L	0.13	0.11	lasso	3	0.12	4.1e-06	7.05	-7.6	3.0e-14	-0.01	0.02	0.98	FALSE
5	CommonMind	Brain Pre-frontal Cortex	TUBA1C	0.41	0.54	lasso	5	0.54	3.0e-77	7.57	7.5	5.8e-14	0.02	0.13	0.87	FALSE
30	GTEx	Pituitary	RP11-386G11.10	0.19	0.11	lasso	5	0.10	1.4e-03	6.18	-7.3	2.5e-13	-0.09	0.06	0.59	FALSE
35	GTEx	Skin Sun Exposed Lower leg	RP11-161H23.5	0.06	0.03	enet	4	0.05	7.3e-05	6.18	-7.1	1.2e-12	-0.16	0.16	0.75	FALSE
59	The Cancer Genome Atlas	Thyroid Carcinoma	LMBR1L	0.03	0.01	blup	24	0.01	1.8e-02	7.99	-7.0	1.9e-12	-0.01	0.01	0.80	FALSE
54	The Cancer Genome Atlas	Brain Lower Grade Glioma	TUBA1C	0.12	0.10	lasso	4	0.10	1.2e-11	7.00	7.0	3.0e-12	0.00	0.01	0.99	FALSE
33	GTEx	Skin Sun Exposed Lower leg	TUBA1C	0.07	0.03	lasso	3	0.05	2.7e-05	5.48	-6.9	4.2e-12	-0.16	0.40	0.52	FALSE
27	GTEx	Muscle Skeletal	RP11-386G11.5	0.09	0.07	enet	17	0.08	7.4e-08	6.13	-6.9	4.5e-12	-0.11	0.99	0.01	FALSE
42	GTEx	Testis	PRKAG1	0.17	0.11	lasso	5	0.09	1.2e-04	6.59	-6.9	7.1e-12	-0.06	0.30	0.64	FALSE
55	The Cancer Genome Atlas	Lung Adenocarcinoma	TUBA1C	0.03	0.04	lasso	2	0.03	7.7e-05	6.88	-6.4	1.8e-10	-0.23	0.04	0.84	FALSE
17	GTEx	Breast Mammary Tissue	LMBR1L	0.09	0.02	enet	19	0.01	5.5e-02	7.93	-6.2	4.0e-10	-0.07	0.02	0.88	FALSE
45	GTEx	Thyroid	SPATS2	0.16	0.04	enet	25	0.05	1.5e-04	3.68	-6.0	2.7e-09	-0.34	0.97	0.00	FALSE
9	GTEx	Artery Aorta	RP11-302B13.1	0.16	0.04	enet	13	0.08	2.9e-05	1.88	-5.9	3.6e-09	-0.02	0.03	0.94	FALSE
50	NTR	Blood	KCNH3	0.03	0.00	bslmm	307	0.00	9.8e-03	2.00	-5.9	4.6e-09	-0.32	0.05	0.09	FALSE
53	The Cancer Genome Atlas	Breast Invasive Carcinoma	SMARCD1	0.02	0.03	lasso	1	0.03	3.7e-06	-5.81	5.8	6.3e-09	0.02	0.01	0.99	FALSE
11	GTEx	Artery Tibial	CCDC65	0.14	0.08	enet	39	0.11	7.9e-09	6.15	5.8	6.8e-09	0.08	0.79	0.20	FALSE
14	GTEx	Brain Caudate basal ganglia	LIMA1	0.18	0.12	lasso	5	0.07	3.9e-03	-5.85	-5.7	9.4e-09	-0.01	0.15	0.10	FALSE
13	GTEx	Artery Tibial	RP4-605O3.4	0.04	0.01	lasso	4	0.00	3.2e-01	-5.24	-5.6	2.0e-08	0.00	0.24	0.04	FALSE
20	GTEx	Cells Transformed fibroblasts	SMARCD1	0.08	0.07	enet	5	0.07	9.3e-06	-5.44	5.6	2.1e-08	0.01	0.99	0.00	FALSE
47	GTEx	Whole Blood	RP4-605O3.4	0.04	0.04	lasso	4	0.01	1.5e-02	-5.21	-5.5	5.1e-08	0.00	0.28	0.03	FALSE
44	GTEx	Thyroid	LIMA1	0.08	0.06	enet	18	0.06	1.7e-05	-4.58	-5.4	5.6e-08	-0.14	0.32	0.05	FALSE
40	GTEx	Testis	CERS5	0.12	0.06	lasso	6	0.07	4.0e-04	-5.51	-5.4	8.4e-08	0.02	0.19	0.06	FALSE
57	The Cancer Genome Atlas	Rectum Adenocarcinoma	SMARCD1	0.40	0.04	blup	48	0.14	4.1e-04	-5.85	5.2	1.6e-07	0.05	0.01	0.69	FALSE
31	GTEx	Skin Sun Exposed Lower leg	SMARCD1	0.07	0.02	lasso	2	0.03	1.4e-03	3.92	5.1	2.7e-07	0.01	0.30	0.04	FALSE