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chr19:9,637,688-12,921,186

Best TWAS P=1.43e-19 · Best GWAS P=8.59e-14 conditioned to 0.00324

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
7	GTEx	Esophagus Mucosa	ILF3-AS1	0.11	0.00	lasso	4	0.00	2.5e-01	7.0	-9.0	1.4e-19	0.01	0.02	0.89	TRUE
16	The Cancer Genome Atlas	Brain Lower Grade Glioma	KANK2	0.28	0.26	lasso	3	0.26	4.6e-29	-7.1	-7.0	2.3e-12	0.82	0.02	0.98	TRUE
2	CommonMind	Brain Pre-frontal Cortex	ZNF788	0.08	0.05	lasso	6	0.04	5.9e-06	5.8	5.5	3.2e-08	0.06	0.01	0.99	TRUE
14	The Cancer Genome Atlas	Breast Invasive Carcinoma	S1PR2	0.02	0.00	blup	32	0.01	1.5e-02	-4.2	5.3	1.5e-07	-0.06	0.01	0.03	TRUE
11	GTEx	Nerve Tibial	ILF3-AS1	0.14	0.04	lasso	3	0.08	3.8e-06	6.8	-8.6	8.6e-18	0.02	0.01	0.98	FALSE
15	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	LOC147727	0.13	0.02	blup	28	0.04	7.2e-05	6.8	-8.5	1.2e-17	0.03	0.01	0.88	FALSE
13	ROSMAP	Brain Pre-frontal Cortex	ILF3-AS1	0.15	0.04	bslmm	354	0.18	7.1e-22	-5.1	-8.3	8.6e-17	-0.02	0.04	0.96	FALSE
3	GTEx	Adipose Subcutaneous	ILF3-AS1	0.18	0.05	enet	27	0.12	1.2e-09	-5.1	-8.2	2.0e-16	0.09	0.14	0.73	FALSE
19	The Cancer Genome Atlas	Thyroid Carcinoma	LOC147727	0.24	0.02	enet	18	0.07	6.1e-07	6.4	-7.4	1.0e-13	-0.06	0.01	0.30	FALSE
17	The Cancer Genome Atlas	Brain Lower Grade Glioma	LOC147727	0.07	0.02	lasso	2	0.02	5.4e-03	7.0	-7.3	2.9e-13	0.04	0.01	0.87	FALSE
8	GTEx	Heart Left Ventricle	ILF3-AS1	0.16	0.06	lasso	9	0.04	3.1e-03	-6.0	-7.3	3.1e-13	-0.04	0.13	0.08	FALSE
9	GTEx	Lung	ILF3-AS1	0.11	0.10	lasso	4	0.09	1.8e-07	-6.0	-7.2	7.2e-13	-0.03	0.68	0.28	FALSE
10	GTEx	Muscle Skeletal	SLC44A2	0.19	0.18	lasso	5	0.19	5.1e-18	6.5	6.9	4.3e-12	0.01	0.10	0.90	FALSE
4	GTEx	Artery Aorta	ILF3-AS1	0.13	0.05	lasso	6	0.06	4.5e-04	-6.0	-6.9	5.9e-12	-0.05	0.36	0.30	FALSE
12	GTEx	Skin Sun Exposed Lower leg	ILF3-AS1	0.14	0.08	enet	14	0.06	5.9e-06	-6.0	-6.2	5.8e-10	-0.03	0.74	0.24	FALSE
5	GTEx	Colon Transverse	ILF3-AS1	0.17	0.11	lasso	4	0.10	2.1e-05	-5.1	-6.1	1.4e-09	-0.07	0.20	0.14	FALSE
18	The Cancer Genome Atlas	Prostate Adenocarcinoma	KANK2	0.09	0.04	blup	76	0.06	9.5e-07	-7.0	-5.6	2.5e-08	0.64	0.01	0.98	FALSE
6	GTEx	Esophagus Mucosa	SLC44A2	0.13	0.00	lasso	6	0.02	1.4e-02	3.6	-5.4	8.5e-08	-0.01	0.06	0.66	FALSE
1	CommonMind	Brain Pre-frontal Cortex	S1PR2	0.07	0.02	bslmm	369	0.03	5.3e-05	-3.9	5.1	3.0e-07	0.01	0.32	0.14	FALSE