Hub : Genes

TACC3

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1060	0.0270	3.0e-09	0.107	0.093	0.116	0.107	0.117	5.9e-13	2.1e-11	5.4e-14	5.4e-13	4.0e-14
2	GTEx	Adipose Subcutaneous	0.1170	0.0410	2.4e-04	0.041	NA	0.007	NA	0.040	2.5e-04	NA	8.2e-02	NA	3.3e-04
3	GTEx	Brain Cortex	0.2590	0.0860	4.3e-03	0.131	NA	0.140	NA	0.172	1.9e-04	NA	1.1e-04	NA	1.8e-05
4	GTEx	Brain Frontal Cortex BA9	0.4273	0.1024	1.9e-04	0.223	NA	0.107	NA	0.175	1.4e-06	NA	9.0e-04	NA	2.2e-05
5	GTEx	Esophagus Muscularis	0.2320	0.0590	7.2e-06	0.079	NA	0.116	NA	0.121	1.6e-05	NA	1.7e-07	NA	9.1e-08
6	GTEx	Muscle Skeletal	0.1617	0.0452	2.4e-06	0.066	NA	0.069	NA	0.078	4.3e-07	NA	2.7e-07	NA	4.4e-08
7	GTEx	Pancreas	0.3030	0.0790	3.2e-06	0.143	NA	0.123	NA	0.137	1.3e-06	NA	7.3e-06	NA	2.2e-06
8	GTEx	Pituitary	0.3700	0.0990	1.4e-03	0.170	NA	0.248	NA	0.255	4.6e-05	NA	6.3e-07	NA	4.3e-07
9	GTEx	Testis	0.1680	0.0680	5.0e-03	0.034	NA	0.036	NA	0.043	1.2e-02	NA	1.0e-02	NA	5.2e-03
10	GTEx	Thyroid	0.1100	0.0420	2.6e-03	0.008	NA	0.005	NA	0.006	7.5e-02	NA	1.2e-01	NA	1.1e-01
11	GTEx	Whole Blood	0.1070	0.0370	9.3e-04	0.054	NA	0.061	NA	0.058	9.7e-06	NA	2.9e-06	NA	4.4e-06
12	METSIM	Adipose	0.0857	0.0240	1.0e-08	0.047	0.053	0.066	0.053	0.071	1.2e-07	1.8e-08	4.0e-10	1.9e-08	7.9e-11
13	NTR	Blood	0.0489	0.0129	6.0e-11	0.029	0.040	0.040	0.040	0.041	1.0e-09	7.8e-13	5.4e-13	5.7e-13	2.7e-13
14	ROSMAP	Brain Pre-frontal Cortex	0.1395	0.0356	3.7e-08	0.109	0.069	0.101	0.101	0.110	7.3e-14	2.9e-09	6.7e-13	5.7e-13	6.1e-14
15	YFS	Blood	0.2152	0.0321	0.0e+00	0.239	0.246	0.267	0.264	0.268	5.8e-77	1.1e-79	2.2e-87	3.9e-86	1.4e-87
16	TCGA	Pheochromocytoma and Paraganglioma	0.0860	0.0440	3.4e-03	0.083	0.095	0.114	NA	0.109	3.4e-04	1.3e-04	2.7e-05	NA	4.3e-05

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
Bipolar Disorder (2018)	0.2	0.3	1.5	0.5	0.7	-0.3	0.4	0.3	0.0	0.2	-0.4	0.5	0.0	-1.2	0.1	-1.0	0.1	-0.5	-0.3
Bipolar Disorder or Schizophrenia	0.2	0.4	2.0	-0.3	1.4	-0.9	-0.7	-0.4	0.0	0.4	-0.3	0.7	0.3	-0.8	0.0	-0.7	-0.6	-0.3	-0.9
Depressed Affect (Nagel 2018)	0.1	0.2	0.9	-0.5	-0.3	-0.2	-0.3	-0.5	-0.6	-0.0	0.2	0.2	-0.0	1.0	-0.2	0.5	-0.6	0.2	-0.2
Depression (Nagel 2018)	0.4	0.6	1.9	0.2	1.4	0.1	-0.3	0.3	0.4	1.4	1.0	-0.8	1.2	0.9	1.1	0.3	-0.0	1.0	0.1
Intelligence (Savage-Jansen 2018)	0.2	0.5	1.3	-1.0	-0.7	-0.6	-1.0	-0.9	-1.2	-0.6	-0.5	0.2	-0.6	0.4	-0.5	0.1	-0.9	-0.3	-0.6
Neuroticism (Nagel 2018)	0.2	0.4	2.8	-0.7	0.1	-0.2	-0.9	-0.6	-0.2	0.1	0.5	-0.4	0.4	1.7	0.3	0.8	-0.6	0.7	-0.1
Schizophrenia (2018)	0.2	0.4	1.7	-0.8	1.2	-0.9	-1.3	-0.4	0.0	0.4	-0.1	0.5	0.4	-0.0	-0.0	-0.1	-0.9	-0.1	-0.9
Schizophrenia vs Biploar Disorder	0.1	0.1	0.3	0.5	0.0	0.3	0.5	0.5	0.0	0.0	-0.1	0.4	-0.0	-0.4	-0.2	0.2	0.6	-0.0	0.4
Worry (Nagel 2018)	0.4	0.8	1.9	-0.1	1.4	0.2	-0.9	0.1	0.5	1.0	1.2	-1.0	1.2	1.1	1.1	0.8	-0.1	1.1	0.2
Alzheimer’s Disease (in mother)	0.2	0.3	0.8	-0.2	0.7	-0.1	-0.4	-0.3	-0.0	0.7	0.7	-0.3	0.7	0.9	0.4	0.7	-0.4	0.6	-0.1
Alzheimer’s Disease (in father)	0.3	0.3	1.7	0.0	-1.3	0.6	0.6	-0.1	-0.5	-0.8	0.0	0.2	-0.2	0.5	-0.5	0.9	0.2	0.2	0.6
Alzheimer’s Disease (including proxy)	0.3	0.5	1.4	-0.9	-0.0	-0.9	-0.9	-1.0	-1.1	-0.3	-0.3	0.6	-0.4	0.4	-0.5	-0.0	-1.2	-0.3	-0.9
Crohns Disease (2017)	0.2	0.4	1.5	0.9	0.7	-0.0	0.9	0.6	0.6	0.3	-0.3	0.4	-0.2	-1.2	0.1	-1.2	0.4	-0.6	-0.1
Irritable Bowel Disease (IBD)	0.8	1.8	4.7	2.1	2.2	0.8	1.5	1.6	2.0	1.6	0.7	-0.5	1.0	-1.0	1.1	-1.0	1.6	0.2	0.8
Ulcerative Colitis (UC)	1.0	1.9	7.1	1.6	2.7	0.7	0.6	1.2	1.8	2.1	1.3	-1.1	1.7	-0.0	1.5	-0.4	1.2	0.9	0.7
Major Depression (MDD)	1.6	1.9	5.3	2.3	1.6	0.8	2.3	2.2	0.0	1.2	0.0	0.0	0.5	-1.8	0.5	-1.6	2.0	-0.3	0.8
Reaction Time	0.3	0.5	1.0	0.7	-0.1	1.0	0.9	0.5	0.8	0.2	0.7	-0.4	0.7	0.8	0.3	0.7	0.9	0.7	1.0
Verbal and Numeric Reasoning (VNR)	0.6	1.5	3.7	-1.8	-1.9	-0.5	-1.2	-1.7	-1.9	-1.4	-0.5	0.4	-0.9	1.0	-1.2	1.3	-1.3	-0.1	-0.5
Breast Cancer	0.5	1.3	4.2	-0.5	2.0	-1.8	-1.1	-0.5	-0.1	1.0	-0.6	0.5	0.1	-1.5	0.3	-1.6	-1.2	-0.9	-1.8
Ovarian Cancer	0.0	0.1	0.3	0.0	0.4	-0.3	-0.1	0.2	0.1	-0.0	-0.2	-0.1	-0.1	0.3	0.3	-0.5	-0.0	-0.3	-0.3
Prostate Cancer	1.1	1.5	2.1	1.2	0.7	1.4	1.2	1.1	1.5	0.9	1.4	-1.3	1.3	1.3	1.2	1.1	1.2	1.4	1.4
Age at First Birth	1.3	1.9	3.8	-1.9	-0.7	-1.7	-1.9	-1.9	-1.9	-0.9	-1.0	1.4	-1.1	-0.1	-0.9	0.0	-1.9	-0.8	-1.7
Bipolar Disorder (2011)	0.1	0.1	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-0.6	-1.0
Body Mass Index (BMI) (2010)	0.2	0.3	0.6	-0.3	0.2	-0.8	-0.2	-0.5	-0.2	-0.0	-0.7	0.4	-0.5	-0.6	-0.3	-0.6	-0.4	-0.8	-0.7
Coronary Artery Disease (CAD)	0.0	0.0	0.2	0.4	-0.0	0.3	0.0	0.1	0.0	-0.1	0.2	-0.1	-0.2	-0.2	0.1	0.2	0.2	0.2	0.3
Crohns Disease (2012)	0.6	1.0	3.3	1.6	-0.1	1.2	1.8	1.2	1.4	-0.2	0.1	-0.1	-0.0	-1.0	-0.1	-0.6	1.6	-0.3	1.1
Mean Putamen Volume	0.6	0.7	1.8	0.3	0.9	0.6	0.3	0.4	0.7	0.9	1.1	-0.9	1.1	1.2	1.0	1.3	0.4	1.1	0.6
Fasting Glucose	0.6	0.7	2.5	0.8	-0.9	0.2	0.6	0.7	0.9	-0.4	-1.0	-0.6	-0.5	0.1	0.0	1.6	1.4	1.0	1.3
HbA1C	1.3	1.4	5.4	0.3	-2.0	1.3	1.2	0.2	-0.8	-0.7	0.9	-0.9	-0.4	1.7	0.2	2.3	0.5	1.3	1.3
HDL Cholesterol	0.3	0.5	1.4	0.9	-0.7	0.9	1.0	0.7	0.7	-0.2	0.3	-0.3	0.1	0.5	0.3	0.8	1.2	0.5	1.1
LDL Cholesterol	0.1	0.1	0.3	-0.4	-0.1	-0.2	-0.2	-0.0	-0.2	-0.4	-0.5	0.5	-0.4	-0.4	-0.5	-0.5	-0.2	-0.6	-0.3
Lupus	0.2	0.3	1.8	0.6	0.6	-0.1	0.6	0.5	0.6	0.2	-0.3	0.3	-0.0	-1.3	0.5	-0.6	0.3	-0.4	-0.2
Neuroticism (2016)	0.2	0.3	1.7	0.1	0.2	0.8	0.3	0.5	0.5	-0.0	0.5	-0.6	0.4	1.3	0.3	0.7	0.5	0.7	0.8
Primary Biliary Cirrhosis	2.9	4.1	14.3	-0.5	-0.6	-1.6	-0.2	-0.8	-0.8	-1.7	-2.7	2.7	-2.5	-3.8	-2.2	-2.8	-0.5	-2.9	-1.6
Rheumatoid Arthritis	0.6	0.8	2.8	0.9	1.7	0.4	0.2	1.0	0.0	1.4	0.9	-0.8	1.1	-0.3	1.0	-0.8	0.7	0.6	0.3
Schizophrenia (2014)	0.3	0.6	1.6	-0.5	1.0	-1.0	-0.8	-0.2	0.0	0.1	-0.8	0.9	-0.3	-1.3	-0.4	-1.0	-0.6	-0.8	-1.0
Triglycerides	0.6	1.0	2.7	1.3	-0.1	1.3	1.4	1.7	1.4	0.4	0.6	-0.9	0.4	0.1	0.4	0.2	1.5	0.5	1.2
Type 2 Diabetes (T2D) (2012)	1.2	1.4	5.4	0.1	2.3	-0.2	-0.8	0.3	0.4	2.0	1.4	-1.3	1.7	0.4	1.8	0.1	-0.5	1.1	-0.3
Ulcerative Colitis	2.6	3.8	8.8	2.3	2.7	1.6	1.4	1.9	3.0	2.4	1.9	-1.9	2.2	-0.1	1.9	0.4	2.0	1.6	1.5
Blood Eosinophil Count	1.2	8.9	13.5	-3.7	-2.2	-3.1	-3.4	-3.6	-3.3	-3.2	-3.1	2.9	-3.1	-0.9	-3.1	-1.8	-3.2	-2.8	-3.1
Blood Platelet Count	0.0	0.4	2.0	-0.4	-1.4	-0.1	0.4	0.1	-0.8	-0.9	-0.8	0.3	-0.9	0.2	-0.3	-0.1	-0.3	-0.6	-0.1
Blood Red Count	0.9	8.5	18.5	-2.2	1.8	-4.3	-3.0	-1.8	-2.2	-0.1	-3.0	2.7	-1.9	-3.7	-1.0	-4.3	-3.0	-3.3	-4.3
Blood White Count	0.1	0.9	2.5	-1.4	-0.1	-1.4	-1.3	-1.1	-1.5	0.1	-0.7	0.1	-0.5	-0.4	0.6	-0.6	-1.6	-0.6	-1.4
Heel T-Score	0.2	1.4	5.2	-1.0	2.3	-1.9	-1.4	-1.0	-0.5	1.4	-0.1	0.7	0.5	-0.4	0.6	0.9	-1.7	-0.3	-1.9
BMI	0.2	1.4	4.4	-1.2	-2.1	-0.4	-0.3	-1.1	-1.5	-2.0	-1.1	1.3	-1.5	0.4	-1.6	0.2	-0.7	-0.9	-0.4
Height	5.4	103.2	219.0	8.8	-5.0	14.5	11.7	7.8	8.1	1.4	9.8	-10.1	6.9	11.7	3.8	14.8	11.1	11.0	14.6
Waist Hip Ratio (WHR)	1.1	4.8	14.6	1.6	3.8	0.4	0.1	2.1	2.4	3.7	2.3	-2.2	2.9	0.1	3.5	0.2	0.9	1.8	0.4
Systolic Blood Pressure	3.7	18.3	23.7	4.2	1.8	4.8	4.1	4.2	3.9	4.1	4.8	-4.9	4.4	3.2	4.7	4.6	4.2	4.8	4.8
Smoking Status	0.4	0.9	2.6	-0.3	-0.6	-0.8	0.0	-0.8	-0.4	-1.2	-1.3	1.2	-1.2	-1.1	-0.9	-1.6	-0.3	-1.4	-0.8
Allergy or Eczema	0.2	0.6	2.0	-1.2	-0.2	-0.9	-1.4	-1.2	-1.0	-0.1	-0.4	0.2	-0.4	0.2	-0.1	-0.2	-1.2	-0.4	-1.0
Cardiovascular Disease	1.2	4.0	6.4	1.7	0.1	2.4	2.0	2.0	1.5	1.7	2.1	-2.0	1.9	1.9	2.3	2.5	1.9	2.3	2.4
Hypothyroidism (self reported)	0.5	1.1	3.3	0.9	-1.8	1.5	1.8	0.5	0.6	-1.0	-0.0	-0.1	-0.4	0.8	-0.7	1.2	1.3	0.2	1.5
Respiratory disease	1.7	3.8	5.8	-1.9	-0.5	-2.4	-1.7	-1.9	-2.3	-1.5	-2.2	2.0	-2.1	-0.9	-1.6	-2.2	-2.1	-2.2	-2.4
Type 2 Diabetes (T2D) (2018)	3.0	5.6	12.0	-1.6	0.3	-3.0	-1.7	-1.8	-1.7	-1.2	-2.7	2.6	-2.2	-3.4	-1.6	-3.5	-2.1	-3.0	-3.0
Lung FEV1/FVC ratio	0.9	4.3	14.5	-0.3	2.2	-2.6	-1.1	-0.3	0.5	0.3	-2.1	2.5	-1.1	-3.6	-1.1	-3.8	-1.1	-2.6	-2.6
Lung FVC	0.8	4.3	15.0	-0.7	3.9	-2.9	-2.4	-0.4	0.4	2.0	-0.9	0.5	0.1	-3.1	0.7	-3.1	-1.6	-1.5	-2.9
Neuroticism	0.3	0.6	2.7	-0.9	0.3	-0.1	-1.3	-0.4	-0.4	0.3	0.8	-0.5	0.6	1.6	0.6	1.2	-0.8	0.9	-0.1
Chronotype (morning person)	3.7	8.6	15.6	2.4	3.3	2.3	0.5	2.9	3.1	3.7	3.5	-3.9	3.7	1.9	4.0	1.4	2.2	3.4	2.3
Hair Pigment	0.0	1.2	2.8	-0.8	-1.5	-0.3	0.5	-0.7	-0.7	-1.5	-1.5	1.5	-1.7	-0.6	-1.3	-0.6	-0.8	-1.3	-0.5
Tanning	0.1	0.8	2.5	0.6	-1.6	1.4	1.4	0.0	0.3	-0.9	0.4	-0.1	-0.1	0.8	-0.4	0.9	0.9	0.7	1.4
Hand grip strength (left)	0.3	0.9	4.1	-1.3	-0.5	-0.2	-1.3	-0.8	-1.2	-0.1	0.4	-0.7	0.2	1.4	0.1	2.0	-1.0	0.7	-0.2
Number of treatments/medications taken	0.5	0.9	1.8	-0.6	-1.3	-0.6	0.2	-0.8	-0.9	-1.3	-1.3	1.3	-1.3	-0.5	-1.3	-0.5	-0.4	-1.2	-0.6
Average weekly spirits intake	4.1	5.1	7.8	-2.5	-0.9	-2.6	-2.2	-2.8	-2.7	-1.9	-2.3	2.6	-2.2	-1.5	-2.0	-1.6	-2.6	-2.2	-2.6
Sensitivity / hurt feelings	0.3	0.6	1.6	-0.9	-1.3	-0.1	-0.5	-0.9	-0.6	-1.2	-0.4	0.5	-0.7	1.2	-0.9	0.8	-0.5	-0.2	-0.1
Frequency of depressed mood in last 2 weeks	0.2	0.3	1.5	-0.2	1.2	-0.5	-0.7	0.0	-0.2	0.9	0.5	-0.4	0.8	0.5	0.6	-0.2	-0.5	0.3	-0.5
Hearing difficulty/problems: Yes	1.7	2.6	6.0	-1.2	-1.9	-1.1	-0.4	-1.2	-1.5	-2.2	-1.9	2.1	-2.1	-1.4	-2.4	-1.3	-1.0	-1.8	-1.1
Relative age of first facial hair	0.4	0.9	1.9	-1.1	-1.4	-0.6	-0.6	-1.1	-1.3	-1.3	-0.9	0.6	-1.1	0.2	-1.1	-0.1	-1.0	-0.8	-0.6
Other serious medical condition/disability diagnosed by doctor	2.0	2.6	5.2	-2.1	-2.1	-1.0	-1.3	-2.1	-2.2	-2.3	-1.0	1.6	-1.3	0.9	-2.1	0.7	-1.8	-0.7	-1.0
Ever used hormone-replacement therapy (HRT)	1.5	1.9	4.8	-1.1	-1.7	-0.8	-0.4	-1.3	-1.2	-2.2	-1.7	1.7	-1.7	-1.0	-2.0	-0.6	-0.7	-1.5	-0.8
Ever had hysterectomy (womb removed)	0.2	0.2	0.8	0.1	0.9	-0.4	-0.2	0.5	0.2	0.8	0.3	-0.2	0.4	0.2	0.7	-0.8	-0.3	0.1	-0.4
Systolic blood pressure, automated reading	1.9	5.4	9.1	2.3	0.8	2.7	2.5	2.1	1.9	2.1	2.5	-2.5	2.3	1.9	2.3	3.0	2.3	2.6	2.7
Eye problems/disorders: Diabetes related eye disease	1.2	1.3	3.1	-0.9	1.0	-1.8	-1.3	-1.1	-0.6	0.1	-1.0	1.0	-0.6	-1.3	-0.2	-1.4	-1.3	-1.2	-1.8
Angina	0.2	0.3	1.1	-0.3	-1.0	0.2	0.2	-0.2	-0.5	-0.9	-0.0	0.5	-0.4	0.8	-0.7	0.7	-0.1	0.1	0.2
Medication for hormone replacement therapy	0.2	0.2	0.6	0.5	-0.7	0.8	0.6	0.5	0.5	-0.3	0.0	-0.1	-0.1	-0.3	-0.5	0.4	0.8	0.1	0.7
Vitamin and mineral supplements	0.7	0.9	1.7	0.8	-0.2	1.3	0.8	0.5	0.9	0.2	1.0	-0.9	0.8	1.2	0.8	1.2	1.0	1.1	1.3
Supplements: Zinc	1.3	1.4	2.8	-1.3	0.4	-1.7	-1.4	-1.1	-1.1	-0.8	-1.1	1.1	-0.8	-0.9	-0.9	-1.4	-1.4	-1.1	-1.6
Medication: Co-codamol	0.6	0.7	3.3	-0.8	-1.8	-0.1	0.0	-1.1	-1.0	-1.1	-0.6	0.6	-1.0	0.7	-0.9	0.2	-0.5	-0.3	-0.1
Medication: Metformin	0.7	1.1	4.9	-0.2	0.4	-1.0	-0.3	-0.3	-0.3	-0.6	-1.1	1.2	-0.8	-2.2	-0.8	-1.7	-0.4	-1.3	-1.0
Diabetes (father)	2.5	3.1	11.0	-0.8	1.1	-2.3	-1.3	-0.8	-0.6	-0.4	-2.0	1.3	-1.4	-2.9	-0.7	-3.3	-1.2	-2.3	-2.3
Diabetes (mother)	2.3	3.0	11.5	-0.4	1.9	-2.3	-1.2	-0.3	-0.3	0.4	-1.5	1.5	-0.8	-3.0	-0.2	-3.4	-1.1	-2.0	-2.3
Severe depression (siblings)	0.2	0.2	1.0	0.2	0.4	0.3	0.2	0.3	0.1	0.6	0.6	-0.6	0.5	1.0	0.6	0.5	0.2	0.6	0.3
Pack years adult smoking proportion	0.8	1.3	6.0	0.1	-2.4	0.4	1.5	-0.2	-0.5	-1.9	-1.2	1.1	-1.7	-0.2	-1.4	-0.3	0.3	-1.0	0.4
Impedance of leg (right)	0.4	2.0	10.3	0.9	2.0	-1.1	-0.0	0.9	0.9	1.1	-0.7	0.6	-0.2	-3.0	0.6	-3.2	0.0	-1.2	-1.1
Leg fat-free mass (left)	2.2	11.8	37.0	2.0	-3.6	5.0	3.9	1.6	1.7	-1.3	2.6	-2.7	1.4	4.6	0.0	6.1	3.5	3.4	5.1
Trunk fat percentage	0.4	1.8	8.0	0.4	-2.8	1.1	1.7	0.4	-0.1	-2.3	-1.1	1.1	-1.6	-0.7	-1.8	0.1	1.1	-0.8	1.1
Hand grip strength (right)	0.4	1.1	3.0	-1.7	-0.9	-0.7	-1.5	-1.1	-1.6	-0.6	-0.0	-0.2	-0.3	1.4	-0.1	1.7	-1.4	0.2	-0.6
Townsend deprivation index at recruitment	2.0	2.8	4.1	1.7	1.0	1.8	1.5	1.5	1.8	1.7	1.9	-1.7	2.0	1.2	1.9	1.2	1.7	1.9	1.8
Current tobacco smoking	1.0	1.7	5.8	-0.1	-0.8	-0.8	0.4	-0.5	-0.1	-1.3	-1.8	1.7	-1.7	-1.6	-1.3	-2.4	-0.0	-1.9	-0.8
Average weekly fortified wine intake	1.2	1.5	3.7	-1.9	-0.8	-1.3	-1.8	-1.9	-1.6	-0.9	-0.5	0.7	-0.7	0.6	-0.6	0.1	-1.9	-0.3	-1.3
Maternal smoking around birth	0.4	0.5	3.0	-0.1	-1.7	0.5	0.5	-0.2	-0.3	-1.3	-0.6	0.7	-0.8	0.1	-1.1	-0.1	0.5	-0.5	0.5
Fed-up feelings	0.3	0.5	2.0	-0.7	-1.4	-0.1	-0.1	-0.9	-1.0	-0.8	-0.4	0.6	-0.6	1.0	-0.6	0.6	-0.6	-0.2	-0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	1.4	1.0	0.7	0.9	0.8	1.0	1.0	1.1	1.0	-1.2	1.0	0.5	1.2	0.4	0.9	0.9	0.9
Relative age voice broke	0.1	0.2	0.5	0.6	-0.1	0.6	0.7	0.5	0.5	0.1	0.2	-0.6	0.1	0.6	0.1	0.2	0.7	0.3	0.6
Taking other prescription medications	0.3	0.5	1.0	-0.1	-0.6	-0.4	0.7	-0.2	-0.5	-1.0	-1.0	0.9	-1.0	-0.7	-0.8	-0.7	-0.2	-1.0	-0.5
Age when periods started (menarche)	0.1	0.4	1.7	-0.2	-1.3	0.2	0.4	-0.5	-0.2	-1.1	-0.5	0.3	-0.7	0.2	-1.0	0.3	0.1	-0.4	0.2
Bilateral oophorectomy (both ovaries removed)	1.2	1.4	3.2	1.6	0.2	1.5	1.8	1.6	1.5	0.7	1.0	-0.9	0.8	0.2	1.3	0.7	1.6	0.8	1.4
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	1.4	0.2	0.7	-0.6	0.3	0.2	0.2	0.2	-0.5	0.7	-0.3	-1.2	-0.2	-0.3	-0.2	-0.6	-0.6
Tinnitus: Yes, but not now, but have in the past	0.6	0.7	3.3	0.4	1.8	-0.4	-0.1	0.2	0.7	1.6	0.7	-0.4	1.1	-0.3	1.2	-0.2	-0.2	0.5	-0.4
Qualifications: CSEs or equivalent	0.3	0.5	1.8	0.0	0.1	-0.5	-0.1	0.0	0.2	-0.5	-0.9	1.1	-0.7	-1.4	-0.7	-0.8	0.1	-1.0	-0.4
Serious illness, injury or assault to yourself	0.2	0.3	1.1	-0.3	-1.1	0.3	0.3	-0.4	-0.2	-0.8	-0.0	-0.0	-0.3	1.0	-0.4	0.9	-0.1	0.2	0.3
High blood pressure	2.9	8.0	13.2	2.8	0.3	3.6	2.9	2.7	2.5	2.1	3.0	-2.9	2.5	2.3	2.6	3.4	3.1	3.2	3.6
Hayfever, allergic rhinitis or eczema	0.4	1.0	2.8	-1.5	-0.5	-1.1	-1.7	-1.6	-1.4	-0.4	-0.4	0.3	-0.4	0.6	-0.2	-0.0	-1.5	-0.3	-1.1
Multivitamins +/- minerals	0.2	0.3	0.7	0.2	-0.6	0.0	0.8	0.4	-0.0	-0.4	-0.6	0.4	-0.8	-0.8	-0.6	-0.4	0.3	-0.7	0.0
Stomach or abdominal pain in last month	0.2	0.3	1.1	0.5	-0.2	0.2	0.7	0.5	0.5	-0.6	-0.5	0.5	-0.5	-1.1	-0.3	-0.7	0.6	-0.5	0.2
Supplements: Glucosamine	1.2	1.5	4.0	-1.8	-1.4	-0.9	-1.3	-1.8	-2.0	-1.6	-0.8	0.8	-0.9	0.6	-1.1	0.6	-1.4	-0.4	-0.9
Diverticular disease/diverticulitis (self-reported)	1.9	2.3	4.7	1.7	1.8	1.1	1.0	2.2	1.9	1.9	1.5	-1.6	1.5	0.3	2.1	0.3	1.4	1.2	1.1
Medication: Atenolol	1.7	2.1	5.1	2.1	0.7	1.7	2.1	2.2	1.8	1.0	1.0	-0.9	1.0	-0.4	1.1	0.3	2.1	0.9	1.6
Medication: Levothyroxine sodium	0.2	0.4	1.6	-0.0	-1.0	0.8	0.4	-0.1	-0.1	-0.8	0.2	-0.4	-0.1	0.9	-0.4	1.3	0.4	0.4	0.8
Sitting height	2.0	14.2	34.5	3.2	-4.0	5.8	5.3	2.9	2.6	-1.4	2.4	-3.0	1.0	3.3	0.1	5.5	4.7	3.0	5.9
Chronic bronchitis/emphysema (father)	0.4	0.4	1.4	0.2	1.2	-0.1	-0.3	0.4	0.2	1.2	0.8	-0.7	0.9	0.4	1.1	0.0	-0.0	0.6	-0.1
High blood pressure (mother)	1.0	1.4	2.7	1.4	-0.0	1.6	1.5	1.1	1.0	0.6	1.0	-1.1	0.9	0.5	1.0	1.2	1.6	1.1	1.6
Body mass index (BMI)	0.2	1.1	4.7	-0.3	-2.2	0.4	0.8	-0.5	-0.7	-1.9	-1.0	1.0	-1.3	0.0	-1.5	0.5	0.2	-0.7	0.4
Impedance of leg (left)	0.4	1.7	8.5	0.4	1.9	-1.4	-0.5	0.6	0.5	1.0	-0.8	0.7	-0.4	-2.6	0.3	-2.9	-0.4	-1.3	-1.4
Leg predicted mass (left)	2.3	12.2	37.5	2.1	-3.6	5.1	4.0	1.7	1.8	-1.2	2.7	-2.8	1.4	4.6	0.1	6.1	3.6	3.5	5.2
Trunk fat mass	0.8	3.6	10.0	1.3	-3.2	2.9	2.8	1.1	0.8	-1.8	0.6	-0.6	-0.3	1.4	-0.9	2.5	2.3	1.0	2.9
Waist circumference	0.9	3.3	10.3	1.0	-2.3	2.7	2.2	0.8	0.8	-1.0	1.2	-1.0	0.5	2.2	-0.2	3.2	1.9	1.7	2.7
Number of incorrect matches in round	1.0	1.6	3.5	0.7	1.6	0.7	0.1	1.1	0.8	1.9	1.6	-1.6	1.7	1.2	1.8	1.2	0.5	1.5	0.7
Past tobacco smoking	0.2	0.4	1.0	-0.5	-0.1	-0.7	-0.4	-0.2	-0.3	-0.2	-0.7	0.6	-0.5	-0.9	-0.5	-1.0	-0.6	-0.7	-0.7
Alcohol usually taken with meals	0.8	1.3	2.5	1.0	0.7	1.1	0.8	1.3	1.0	1.3	1.3	-1.6	1.2	1.0	1.2	1.2	1.0	1.2	1.1
Nervous feelings	0.1	0.2	0.8	-0.3	0.9	-0.5	-0.9	-0.1	0.2	0.4	0.1	-0.2	0.3	-0.1	0.6	-0.5	-0.4	0.0	-0.5
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.4	1.0	1.0	0.8	0.2	0.9	1.0	0.7	0.5	0.0	0.0	0.2	-0.6	-0.0	-0.8	0.8	-0.2	0.2
Hearing difficulty/problems with background noise	3.5	5.7	8.5	-2.3	-1.7	-2.4	-1.7	-2.2	-2.4	-2.5	-2.7	2.9	-2.6	-1.7	-2.9	-2.3	-2.2	-2.7	-2.4
Hair/balding pattern: Pattern 2	0.1	0.1	0.4	-0.3	-0.3	-0.2	-0.2	-0.2	-0.5	-0.5	-0.4	0.6	-0.4	-0.1	-0.6	0.0	-0.2	-0.3	-0.2
Had menopause	0.6	0.7	2.0	-1.2	0.2	-1.1	-1.3	-1.4	-1.1	-0.3	-0.4	0.6	-0.1	0.2	-0.5	-0.3	-1.3	-0.2	-1.1
Had other major operations	0.8	1.0	3.8	-0.4	-1.9	0.1	0.5	-0.6	-0.7	-1.9	-1.1	0.9	-1.2	-0.4	-1.7	-0.2	0.0	-0.8	0.1
Forced vital capacity (FVC)	1.3	4.9	8.8	2.0	2.2	1.8	1.1	1.9	2.7	2.6	2.5	-3.0	2.6	1.4	2.5	2.2	1.8	2.4	1.8
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	3.0	0.2	1.0	-0.8	0.2	0.1	0.0	0.1	-0.6	1.0	-0.3	-1.7	-0.4	-0.5	-0.3	-0.8	-0.9
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	1.1	-1.1	-0.6	-0.8	-0.7	-0.7	-1.0	-0.5	-0.6	0.4	-0.7	0.1	-0.1	-0.1	-1.0	-0.5	-0.8
Qualifications: None of the above	2.6	5.7	10.6	3.2	1.3	2.9	3.2	2.6	2.7	1.9	2.2	-2.2	2.1	1.4	2.0	1.0	3.0	2.1	2.8
Financial difficulties in last 2 years	0.4	0.6	1.7	0.6	-1.3	1.1	1.1	0.3	0.0	-0.8	0.2	-0.3	-0.1	1.0	-0.2	0.5	0.9	0.4	1.1
Mouth/teeth dental problems	0.9	1.3	4.5	-1.1	1.9	-1.8	-2.1	-0.8	-0.8	0.8	-0.2	0.4	0.3	-0.6	0.1	-0.8	-1.5	-0.4	-1.8
Heart attack	1.0	1.2	5.0	1.9	0.1	1.1	2.2	1.5	1.5	0.1	0.1	0.0	0.2	-1.1	0.0	-0.7	1.7	-0.0	1.1
Allergy	0.3	0.8	1.7	1.2	0.2	1.1	1.3	1.3	1.3	0.2	0.6	-0.5	0.6	-0.4	0.1	0.4	1.2	0.6	1.1
Pain all over the body in last month	0.4	0.5	1.8	-0.9	-0.9	-0.1	-0.9	-1.0	-1.4	-0.5	0.2	-0.3	0.1	0.7	-0.0	0.6	-0.7	0.4	-0.1
Diabetes (self-reported)	2.2	3.3	8.7	-1.0	0.3	-2.1	-1.1	-1.2	-1.0	-1.1	-2.1	2.2	-1.7	-2.8	-1.4	-2.9	-1.3	-2.4	-2.2
Hayfever/allergic rhinitis (self-reported)	0.0	0.1	0.1	0.2	-0.4	0.1	0.3	0.1	0.0	-0.2	-0.3	0.1	-0.4	-0.3	-0.2	-0.3	0.1	-0.3	0.1
Medication: Ramipril	1.7	2.2	3.2	1.8	1.0	1.7	1.3	1.8	1.7	1.6	1.6	-1.4	1.6	0.5	1.5	0.9	1.8	1.5	1.6
Medication: Simvastatin	1.5	2.3	3.6	1.7	1.1	1.5	1.5	1.9	1.8	1.6	1.6	-1.6	1.6	0.4	1.6	0.8	1.6	1.5	1.5
Fluid intelligence score	0.8	1.6	4.8	-1.5	-2.2	-0.0	-0.8	-1.6	-1.7	-1.9	-0.4	0.5	-0.9	1.6	-1.6	1.6	-0.9	-0.0	-0.0
Illnesses of siblings	3.6	5.0	10.3	-3.2	-2.5	-1.7	-2.9	-3.1	-2.8	-2.8	-1.5	1.6	-1.9	0.9	-2.5	0.7	-2.6	-1.0	-1.7
Neuroticism score	0.2	0.4	1.2	-0.0	0.7	0.2	-0.4	0.4	0.5	0.7	0.7	-0.6	0.8	1.1	0.7	0.6	0.0	0.7	0.2
Weight	1.8	8.8	25.7	1.9	-3.2	4.4	3.6	1.5	1.5	-1.2	2.1	-2.2	1.1	3.7	0.0	5.1	3.1	2.8	4.5
Impedance of arm (right)	0.2	1.1	7.1	0.6	0.5	-0.5	0.0	0.9	0.6	0.3	-0.8	0.6	-0.6	-2.4	0.0	-2.7	0.3	-1.1	-0.5
Arm fat percentage (right)	0.3	1.2	4.6	0.1	-2.1	0.6	1.1	0.2	-0.2	-1.9	-1.1	1.2	-1.5	-1.0	-1.5	-0.5	0.7	-1.0	0.5
Trunk fat-free mass	4.1	23.5	72.6	3.1	-2.6	6.6	4.7	2.5	3.0	0.5	4.9	-4.9	3.5	6.8	1.9	8.5	4.5	5.7	6.7
Hip circumference	1.6	6.7	25.9	0.5	-5.1	3.5	2.8	-0.0	-0.2	-3.2	0.5	-0.5	-0.8	3.0	-1.9	4.4	2.0	1.4	3.5
Time employed in main current job	2.3	2.6	5.5	2.0	0.6	2.2	1.8	1.9	2.0	0.7	1.6	-1.5	1.4	0.5	1.0	1.1	2.3	1.4	2.2
Alcohol intake versus 10 years previously	1.1	1.7	4.6	1.8	2.1	0.7	1.2	1.2	1.9	1.6	1.0	-1.1	1.4	-0.9	1.3	-0.5	1.3	0.7	0.7
Father’s age at death	3.1	4.1	9.2	-2.3	1.0	-3.0	-3.0	-2.2	-2.2	-0.5	-1.4	1.5	-0.9	-1.9	-0.7	-2.1	-2.7	-1.6	-3.0
Worrier / anxious feelings	2.2	4.1	7.5	2.0	2.7	1.5	0.7	2.2	2.4	2.7	2.3	-2.1	2.6	0.8	2.5	0.6	1.7	2.0	1.4
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	0.9	0.7	-0.2	0.8	1.0	0.7	0.5	0.0	0.4	-0.3	0.2	0.6	-0.1	0.3	0.8	0.4	0.8
Falls in the last year	0.5	0.7	2.6	0.6	-1.6	1.2	1.6	0.3	0.4	-1.0	-0.1	0.1	-0.2	0.3	-0.7	0.5	0.9	0.1	1.1
Hair/balding pattern: Pattern 3	1.5	2.3	3.5	1.7	1.6	1.3	1.2	1.2	1.7	1.8	1.8	-1.6	1.9	1.0	1.8	1.0	1.4	1.6	1.3
Number of live births	0.0	0.1	0.3	0.1	-0.2	0.0	0.0	0.1	0.1	-0.4	-0.3	0.1	-0.3	0.1	-0.2	-0.5	0.1	-0.4	-0.0
Forced expiratory volume in 1-second (FEV1)	0.5	1.6	5.6	1.0	2.4	0.2	0.0	1.2	2.0	2.0	1.1	-1.5	1.6	-0.1	1.6	0.5	0.6	0.9	0.3
Pulse rate	1.7	2.9	6.5	-0.8	-1.4	-1.2	-0.3	-0.8	-1.2	-1.9	-2.2	2.2	-2.2	-2.1	-2.0	-2.5	-0.7	-2.3	-1.3
Happiness	0.4	0.4	1.3	0.3	-1.2	0.4	0.9	0.3	-0.1	-1.0	-0.7	0.5	-0.8	-0.8	-0.7	-0.3	0.6	-0.7	0.4
Noisy workplace	0.2	0.2	0.8	-0.3	-0.7	-0.2	-0.0	-0.2	-0.1	-0.9	-0.5	0.5	-0.7	0.5	-0.8	0.3	-0.2	-0.4	-0.1
Qualifications: A levels/AS levels or equivalent	1.9	4.1	7.0	-2.6	-1.2	-2.3	-2.6	-2.1	-2.3	-1.6	-2.0	2.0	-1.8	-1.3	-1.8	-1.4	-2.4	-1.9	-2.4
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	2.1	0.7	1.4	-0.3	0.2	0.4	0.7	0.7	0.0	0.1	0.4	-0.9	0.3	-1.2	0.2	-0.2	-0.3
Mouth/teeth dental problems: Dentures	1.2	2.1	13.5	-0.4	-3.7	1.0	1.3	-1.0	-0.9	-2.4	-0.7	0.5	-1.4	1.4	-1.4	1.2	0.2	-0.2	1.0
Asthma	0.6	1.2	2.3	-1.0	0.3	-1.5	-1.4	-0.9	-1.2	-0.6	-1.2	1.0	-1.0	-0.5	-0.5	-1.4	-1.2	-1.3	-1.5
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	1.3	-1.0	-0.9	-0.3	-1.0	-1.1	-0.7	-0.8	-0.3	0.3	-0.4	1.1	-0.8	0.8	-0.7	-0.1	-0.3
Medication: Cholesterol lowering	0.1	0.1	0.4	0.3	-0.4	0.3	0.6	0.2	0.4	-0.3	-0.1	0.2	-0.2	-0.5	-0.2	0.2	0.3	-0.0	0.3
Depression (self-reported)	0.5	0.6	1.1	0.9	0.9	0.7	0.8	0.7	0.9	1.0	0.9	-0.9	0.9	0.4	0.8	0.4	0.8	0.8	0.7
Medication: Lansoprazole	0.7	0.8	2.7	0.5	-0.7	1.3	0.7	0.1	0.3	-0.2	1.0	-0.7	0.6	1.4	0.5	1.6	0.8	1.1	1.3
Prospective memory result	0.1	0.1	0.2	0.4	0.2	0.4	0.4	0.4	0.3	0.2	0.1	-0.3	0.2	0.4	0.3	-0.1	0.4	0.1	0.4
Lung cancer (father)	0.5	0.6	1.2	-1.0	-1.0	-0.3	-0.7	-0.9	-0.9	-1.1	-0.5	0.7	-0.7	0.7	-0.9	0.8	-0.6	-0.2	-0.2
Illnesses of mother	1.0	1.3	3.6	-1.7	-0.2	-1.5	-1.9	-1.4	-1.3	-0.4	-0.7	0.4	-0.7	-0.1	-0.3	-0.5	-1.8	-0.6	-1.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.8	5.9	1.0	2.4	0.3	-0.1	1.3	1.9	2.1	1.2	-1.7	1.7	-0.0	1.8	0.5	0.7	1.0	0.4
Pulse wave Arterial Stiffness index	0.1	0.1	0.4	0.0	-0.3	0.3	0.3	-0.2	0.1	-0.4	0.2	0.2	0.1	0.5	-0.2	0.7	0.1	0.3	0.3
Impedance of arm (left)	0.2	1.1	6.0	0.1	0.4	-0.8	-0.3	0.5	0.2	0.0	-1.0	0.8	-0.8	-2.3	-0.2	-2.4	-0.1	-1.3	-0.8
Arm fat mass (right)	0.5	2.0	8.4	0.5	-2.9	1.9	1.9	0.3	0.1	-1.9	-0.0	0.0	-0.7	1.2	-1.1	1.9	1.3	0.4	1.9
Trunk predicted mass	4.2	23.7	72.4	3.2	-2.5	6.6	4.7	2.6	3.0	0.5	4.9	-4.9	3.5	6.8	1.9	8.5	4.5	5.7	6.7
Standing height	4.2	41.3	104.0	4.8	-2.6	8.8	6.3	4.2	4.8	1.4	6.7	-6.9	4.9	8.1	3.0	10.2	6.3	7.5	8.9
Length of working week for main job	0.6	0.7	2.5	-0.5	-1.5	0.1	-0.0	-0.3	-0.8	-1.6	-0.8	0.7	-1.2	0.2	-1.3	0.1	-0.0	-0.8	0.1
Exposure to tobacco smoke at home	8.9	10.0	15.3	3.9	1.7	3.7	3.3	3.8	3.9	2.7	3.2	-3.0	3.2	1.2	2.8	1.6	3.9	3.0	3.7
Breastfed as a baby	1.7	2.1	5.7	-2.2	-0.6	-1.5	-2.4	-2.3	-2.0	-1.0	-0.7	1.1	-0.7	0.6	-1.3	0.6	-2.0	-0.6	-1.5
Tense / ‘highly strung’	0.2	0.3	1.0	0.5	1.0	-0.1	0.1	0.6	0.7	0.6	0.2	-0.3	0.4	-0.6	0.7	-0.9	0.2	0.1	-0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.7	1.7	0.6	1.1	0.5	0.2	0.6	0.9	1.0	0.9	-1.2	1.1	0.6	1.3	-0.1	0.6	0.9	0.5
Hair/balding pattern: Pattern 4	0.4	1.0	3.2	0.7	-1.8	1.5	1.7	0.8	0.6	-0.9	-0.1	-0.1	-0.5	0.0	-0.7	1.1	1.4	0.1	1.5
Birth weight of first child	0.7	1.3	3.6	0.3	0.1	1.1	-0.1	0.7	0.8	0.8	1.5	-1.8	1.1	1.7	1.2	1.9	0.6	1.5	1.1
Peak expiratory flow (PEF)	1.2	2.8	10.5	0.1	2.9	-2.1	-1.2	0.3	0.7	1.3	-1.1	0.6	-0.1	-3.2	0.2	-2.9	-0.7	-1.6	-2.1
Pulse wave reflection index	3.4	4.2	6.4	-2.4	-0.7	-2.5	-2.4	-2.4	-2.1	-1.5	-2.1	2.1	-1.9	-1.3	-1.8	-1.7	-2.4	-2.0	-2.5
Ever highly irritable/argumentative for 2 days	0.6	0.7	2.6	-0.1	0.7	-1.1	-0.4	0.1	0.1	0.1	-1.0	1.1	-0.6	-1.3	-0.4	-1.6	-0.4	-1.2	-1.1
Loud music exposure frequency	1.4	1.5	4.4	1.9	0.7	1.2	2.1	1.5	1.9	1.1	0.6	-0.4	0.7	-0.7	0.6	-0.2	1.8	0.4	1.2
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	1.8	-1.1	-0.0	-1.0	-1.4	-0.6	-1.0	-0.2	-0.6	0.6	-0.4	-0.8	-0.4	-0.3	-1.1	-0.6	-1.1
Mouth/teeth dental problems: Bleeding gums	1.0	1.3	3.0	1.5	-0.2	1.7	1.6	1.4	1.3	0.4	0.7	-0.8	0.5	0.3	0.6	0.5	1.7	0.8	1.7
Blood clot in the leg (DVT)	0.5	0.6	1.1	0.8	-0.1	1.0	0.9	0.8	0.7	0.4	0.8	-0.9	0.7	0.8	0.6	0.9	0.8	0.9	1.0
Medication: Paracetamol	1.4	2.2	6.2	-0.9	-2.3	-0.5	-0.0	-0.9	-1.1	-2.5	-2.0	1.7	-2.1	-0.5	-2.4	-1.0	-0.4	-1.7	-0.5
Headache pain in last month	0.6	1.0	2.6	1.5	0.6	0.8	1.4	1.6	1.4	0.3	-0.1	0.0	0.2	-1.5	0.2	-0.9	1.5	-0.2	0.7
Medication for cholesterol, blood pressure or diabetes	0.7	1.1	2.8	-1.5	-0.4	-1.2	-1.7	-1.3	-1.4	-0.8	-0.8	0.8	-0.8	0.4	-0.9	-0.7	-1.4	-0.7	-1.2
Glaucoma (self-reported)	1.2	1.4	3.9	-0.7	-1.5	-0.5	-0.1	-0.9	-0.6	-2.0	-1.5	1.8	-1.6	-0.4	-1.9	-0.8	-0.4	-1.4	-0.6
Gout (self-reported)	0.9	1.3	2.5	1.4	0.3	1.5	1.6	0.9	1.1	0.5	1.1	-0.5	1.1	1.1	0.2	1.2	1.5	1.2	1.6
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	2.1	0.7	-1.2	1.1	1.5	0.4	0.4	-0.8	-0.2	0.1	-0.4	0.2	-0.6	0.7	1.1	-0.0	1.0
Medication: Amlodipine	0.6	0.9	3.4	0.2	-1.1	1.1	0.9	0.3	0.4	0.2	0.8	-0.9	0.4	1.8	0.4	1.7	0.5	1.1	1.1
Medication: Ventolin 100micrograms inhaler	3.2	4.1	6.9	-1.6	0.1	-2.6	-1.6	-1.7	-1.8	-1.2	-2.5	2.3	-2.1	-2.1	-1.7	-2.5	-1.9	-2.6	-2.6
Birth weight	3.3	7.2	14.2	2.8	-0.1	3.8	2.8	2.6	2.5	1.4	2.9	-2.8	2.4	1.9	1.9	3.0	3.2	3.0	3.8
Chronic bronchitis/emphysema (mother)	0.6	0.7	3.1	-0.1	-1.8	0.4	0.6	-0.1	-0.4	-1.6	-0.9	0.7	-1.0	-0.7	-1.2	0.1	0.4	-0.7	0.4
High blood pressure (siblings)	3.9	5.7	9.5	3.0	2.6	2.1	2.4	2.8	2.7	3.1	2.3	-2.3	2.5	0.2	2.9	0.4	2.6	2.0	2.0
Forced vital capacity (FVC), Best measure	1.2	4.3	8.6	1.7	1.7	1.9	1.0	1.8	2.3	2.2	2.4	-2.9	2.4	1.5	2.3	2.4	1.7	2.4	1.9
Body fat percentage	0.4	1.5	6.1	0.2	-2.5	0.7	1.3	0.2	-0.2	-2.1	-1.2	1.2	-1.6	-1.0	-1.7	-0.3	0.7	-1.0	0.7
Leg fat percentage (right)	0.1	0.5	1.4	0.2	-1.1	0.2	0.7	0.1	-0.1	-1.2	-0.7	0.8	-0.9	-0.8	-0.8	-0.5	0.3	-0.7	0.2
Arm fat-free mass (right)	2.6	13.4	46.4	2.1	-2.8	5.0	3.8	1.6	1.8	-0.5	3.3	-3.4	2.1	5.4	0.7	6.8	3.3	4.0	5.1
Exposure to tobacco smoke outside home	5.3	7.1	9.1	2.9	1.5	3.0	2.4	2.8	2.9	2.2	2.9	-3.0	2.8	2.3	2.7	2.0	2.9	2.8	3.0
Comparative body size at age 10	0.4	1.0	3.5	1.6	0.7	0.8	1.4	1.9	1.2	1.1	0.2	-0.3	0.4	-0.9	0.7	-0.4	1.4	0.1	0.8
Number of full brothers	3.4	4.2	9.0	2.9	1.9	2.1	2.3	2.8	3.0	1.9	1.7	-1.4	1.9	-0.2	1.8	-0.1	2.8	1.3	2.0
Worry too long after embarrassment	0.8	1.4	6.4	-1.5	1.4	-1.3	-2.5	-1.2	-0.7	0.7	0.6	-0.3	0.7	1.1	0.9	0.5	-1.7	0.5	-1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.2	0.4	-0.5	0.3	-0.3	-0.5	-0.4	-0.2	0.2	0.2	-0.4	0.4	0.6	0.6	-0.2	-0.4	0.3	-0.3
Wheeze or whistling in the chest in last year	0.4	0.6	2.0	-0.1	-0.2	-0.7	-0.1	-0.2	-0.4	-0.8	-1.2	1.0	-0.9	-1.3	-0.6	-1.4	-0.1	-1.2	-0.7
Number of children fathered	1.1	1.2	3.8	0.5	-1.9	1.6	1.3	-0.2	0.3	-0.9	0.5	-0.8	-0.2	1.6	-0.6	1.5	1.0	0.7	1.6
Reason for reducing amount of alcohol drunk: Health precaution	2.6	3.0	12.5	-2.6	0.8	-2.1	-3.5	-2.4	-2.3	0.2	-0.1	-0.3	0.2	0.8	0.4	0.1	-2.7	0.1	-2.1
Age at first live birth	0.1	0.3	0.7	-0.8	-0.5	-0.3	-0.7	-0.5	-0.9	-0.1	0.2	-0.2	-0.0	0.4	-0.0	0.8	-0.8	0.2	-0.3
Pulse wave peak to peak time	0.2	0.2	0.7	0.4	0.2	0.4	0.3	0.6	0.3	0.7	0.4	-0.8	0.4	0.2	0.5	0.2	0.4	0.4	0.4
Health satisfaction	1.3	1.7	5.2	1.6	-0.6	1.8	2.3	1.5	1.2	0.2	0.8	-0.9	0.6	1.2	0.6	1.2	1.7	1.0	1.8
Shortness of breath walking on level ground	0.3	0.3	0.8	-0.1	-0.1	-0.5	-0.1	-0.2	-0.4	-0.6	-0.8	0.8	-0.8	-0.5	-0.5	-0.9	-0.2	-0.8	-0.5
Qualifications: College or University degree	0.8	2.6	5.2	-2.2	-0.7	-2.0	-2.2	-1.6	-1.9	-1.0	-1.4	0.9	-1.4	-1.0	-1.1	-1.0	-2.3	-1.4	-2.1
Eye problems/disorders: None of the above	0.1	0.2	0.8	-0.2	-0.3	-0.2	-0.1	-0.3	-0.3	-0.3	-0.3	0.5	-0.4	-0.9	-0.6	-0.4	-0.2	-0.4	-0.2
Mouth/teeth dental problems: Loose teeth	1.1	1.3	3.3	-0.7	-1.8	-0.4	0.1	-1.2	-1.3	-1.8	-1.2	1.5	-1.6	-0.2	-1.6	-0.4	-0.6	-1.1	-0.4
Emphysema/chronic bronchitis	0.4	0.5	2.0	0.4	-1.4	0.5	1.4	0.1	-0.2	-0.8	-0.6	0.5	-0.8	-0.4	-0.5	-0.1	0.6	-0.6	0.5
Medication for pain relief, constipation, heartburn	0.2	0.3	1.2	-0.1	1.1	-0.2	-0.7	0.1	-0.1	0.9	0.7	-0.6	0.8	0.1	0.9	0.2	-0.3	0.5	-0.2
Neck or shoulder pain in last month	1.9	2.8	6.1	1.9	-0.6	2.4	2.5	1.9	1.7	0.1	1.3	-1.3	0.9	1.4	0.6	1.7	2.1	1.4	2.4
Medication: Blood pressure	1.5	2.6	6.0	2.3	0.3	2.0	2.4	2.2	1.9	1.2	1.1	-1.0	1.0	-0.3	1.3	0.8	2.3	1.0	2.0
Angina (self-reported)	0.3	0.4	1.5	-0.4	-1.2	0.1	0.1	-0.3	-0.6	-1.2	-0.3	0.8	-0.6	0.6	-0.9	0.5	-0.2	-0.1	0.1
Migraine (self-reported)	0.9	1.1	3.4	0.9	1.8	-0.3	0.2	1.6	1.2	1.6	0.2	-0.4	0.6	-1.2	1.1	-1.6	0.5	-0.1	-0.2
Medication: Ibuprofen	0.4	0.5	1.3	-1.1	-0.6	-0.5	-1.1	-1.1	-0.8	-0.6	-0.3	0.3	-0.3	0.8	-0.5	0.4	-0.8	-0.2	-0.5
Medication: Allopurinol	1.3	1.7	3.7	1.9	1.2	1.4	1.7	1.9	1.7	1.1	1.0	-0.6	1.2	-0.1	0.9	-0.0	1.8	0.9	1.4
Medication: Omeprazole	1.9	2.3	4.5	-0.7	-1.2	-1.2	0.3	-1.1	-0.9	-1.7	-2.1	1.9	-2.0	-1.8	-1.9	-1.8	-0.8	-2.0	-1.2
Medication: Seretide 50 evohaler	4.9	5.7	8.9	-2.4	-0.7	-3.0	-2.0	-2.3	-2.7	-1.8	-2.6	2.5	-2.4	-1.9	-2.1	-2.4	-2.7	-2.7	-3.0
Mean time to correctly identify matches	0.5	1.0	2.0	0.9	-0.2	1.4	1.1	0.6	0.8	0.3	1.2	-0.7	1.0	1.3	0.5	1.2	1.0	1.2	1.4
Heart disease (mother)	3.3	4.1	6.0	2.0	1.3	2.1	1.7	2.1	2.4	1.8	2.3	-2.0	2.1	1.6	1.9	2.3	2.1	2.2	2.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.3	-0.4	-0.5	-0.1	-0.1	-0.5	-0.3	-0.1	0.0	-0.3	-0.1	0.0	0.1	0.5	-0.3	0.1	-0.1
Whole body fat mass	0.8	3.2	8.3	1.3	-2.9	2.8	2.7	1.1	0.8	-1.6	0.6	-0.5	-0.2	1.2	-0.8	2.4	2.2	1.0	2.8
Leg fat mass (right)	0.6	2.2	6.2	1.1	-2.5	2.2	2.3	0.9	0.6	-1.6	0.2	-0.2	-0.4	0.9	-0.8	1.8	1.8	0.6	2.2
Arm predicted mass (right)	2.7	13.9	47.2	2.2	-2.9	5.2	4.0	1.7	2.0	-0.4	3.3	-3.4	2.1	5.4	0.7	6.9	3.5	4.1	5.2
Pulse rate, automated reading	2.1	6.8	15.7	-1.3	-1.3	-2.2	-0.7	-1.2	-1.4	-2.4	-3.4	3.5	-3.3	-3.5	-3.0	-4.0	-1.3	-3.6	-2.2
Alcohol intake frequency.	1.7	4.0	9.4	3.1	1.7	2.0	2.8	2.6	3.0	1.5	1.3	-1.5	1.5	-0.2	1.4	-0.2	2.9	1.0	2.0
Comparative height size at age 10	4.2	22.9	96.8	1.2	-3.1	5.7	2.5	0.5	1.2	0.3	5.3	-5.1	3.6	8.2	1.9	9.8	2.5	6.3	5.8
Number of full sisters	0.9	1.1	3.2	0.4	1.8	0.2	-0.5	0.2	0.7	1.7	1.2	-1.3	1.4	0.8	1.8	0.1	0.2	1.1	0.2
Suffer from ‘nerves’	0.9	1.4	3.2	1.2	-0.5	1.8	1.4	1.3	1.2	-0.1	1.0	-1.0	0.6	1.3	0.4	1.3	1.5	1.0	1.8
Overall health rating	1.9	4.1	9.6	2.0	-1.4	3.0	3.1	1.8	1.8	-0.1	1.6	-1.5	1.0	2.4	0.6	2.2	2.5	1.8	3.0
Chest pain or discomfort	0.4	0.5	2.1	0.8	0.8	-0.2	0.9	0.4	0.7	0.3	-0.5	0.9	-0.1	-1.4	-0.2	-1.4	0.6	-0.6	-0.2
Had major operations	0.3	0.3	1.0	0.5	-0.7	0.6	1.0	0.4	0.6	-0.8	-0.2	0.5	-0.4	-0.6	-0.7	0.1	0.6	-0.2	0.6
Age at last live birth	0.6	0.9	2.5	-1.6	-0.8	-0.8	-1.6	-1.5	-1.4	-0.8	-0.2	0.2	-0.5	0.6	-0.5	0.6	-1.4	-0.1	-0.8
Family relationship satisfaction	0.4	0.5	1.3	0.6	-1.0	0.9	1.1	0.7	0.4	-0.8	-0.2	-0.0	-0.5	-0.5	-0.5	0.0	1.0	-0.2	0.9
Leg pain on walking	1.0	1.3	4.9	-0.1	-2.2	0.3	1.0	-0.5	-0.5	-2.1	-1.2	1.4	-1.5	0.1	-1.8	-0.2	0.3	-1.0	0.3
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	1.7	-0.0	0.5	0.1	-0.2	0.2	-0.0	0.8	0.7	-0.6	0.7	1.3	0.7	0.9	-0.1	0.8	0.1
Commuting to job workplace: Car/motor vehicle	4.4	5.1	9.4	-1.8	-2.2	-1.7	-1.1	-1.8	-2.2	-3.0	-2.7	2.8	-2.8	-1.8	-3.1	-2.0	-1.5	-2.6	-1.7
Illness, injury, bereavement, stress in last 2 years	0.3	0.3	1.8	-0.5	-1.3	0.4	0.0	-0.3	-0.6	-0.7	-0.1	-0.1	-0.4	0.3	-0.5	1.2	-0.1	0.2	0.4
Medication: Aspirin	0.3	0.4	0.8	0.4	-0.0	0.6	0.6	0.3	0.5	0.4	0.7	-0.6	0.6	0.8	0.7	0.9	0.4	0.7	0.6
Supplements: Vitamin C	0.4	0.5	1.8	-0.7	1.1	-0.8	-1.3	-0.6	-0.6	0.6	0.3	-0.3	0.6	0.4	0.3	-0.0	-0.9	0.3	-0.8
Knee pain experienced in last month	1.6	2.5	12.6	-0.7	-3.5	1.3	0.9	-0.7	-0.9	-2.4	-0.2	0.2	-1.0	2.5	-1.6	2.5	0.2	0.4	1.3
Hypertension (Self-reported)	3.2	8.8	14.3	3.0	0.4	3.8	3.1	2.9	2.8	2.2	3.1	-3.0	2.7	2.2	2.8	3.3	3.3	3.3	3.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.0	0.0	0.1	0.0	0.1	0.0	-0.0	0.3	0.1	0.3	0.1	-0.2	0.1	-0.2	0.2	0.2	-0.0	0.2	0.0
Illnesses of father: Heart disease	0.7	1.0	2.2	1.1	0.0	1.2	1.5	1.1	0.7	0.8	1.0	-0.7	0.9	0.8	0.6	1.1	1.1	1.1	1.3
Illnesses of siblings: Diabetes	1.8	2.2	8.4	1.2	2.9	-0.7	-0.1	1.4	1.6	1.5	-0.2	-0.0	0.5	-2.7	1.1	-2.7	0.6	-0.8	-0.8
Smoking status: Previous	0.4	0.5	1.3	-0.0	0.9	0.1	-0.6	-0.0	0.1	0.8	0.9	-0.9	0.9	1.0	1.0	1.1	-0.2	0.9	0.1
Forced expiratory volume in 1-second (FEV1), predicted	1.0	2.1	11.0	0.0	-1.1	1.5	0.4	0.1	0.2	-0.0	1.4	-1.6	0.7	2.7	0.5	3.3	0.5	1.7	1.6
Whole body fat-free mass	3.3	18.8	59.8	2.7	-3.1	6.1	4.5	2.2	2.5	-0.3	4.0	-4.1	2.6	6.1	1.1	7.7	4.2	4.8	6.2
Leg fat-free mass (right)	2.3	12.3	41.9	1.9	-3.6	5.0	3.7	1.5	1.6	-1.1	2.8	-2.9	1.6	5.0	0.1	6.5	3.3	3.6	5.1
Arm fat percentage (left)	0.4	1.4	5.5	-0.0	-2.3	0.5	1.1	0.1	-0.4	-2.1	-1.3	1.3	-1.6	-0.9	-1.6	-0.3	0.6	-1.1	0.5
Average weekly red wine intake	0.0	0.0	0.1	-0.0	-0.1	-0.0	0.1	0.1	-0.2	0.3	-0.1	-0.3	-0.2	0.2	0.3	-0.1	-0.1	0.0	-0.0
Handedness (chirality/laterality): Left-handed	0.7	0.8	2.2	0.7	-1.5	1.4	1.3	0.9	0.2	-0.7	0.2	-0.4	-0.2	1.0	-0.0	1.1	1.1	0.4	1.4
Mood swings	0.4	0.7	1.3	0.8	-0.3	1.1	1.0	0.9	0.7	0.5	0.9	-0.6	0.7	1.0	0.6	0.7	0.9	1.0	1.1
Loneliness, isolation	0.2	0.3	0.9	0.7	-0.3	0.6	0.9	0.7	0.7	0.2	0.2	-0.3	0.2	-0.4	-0.0	-0.0	0.8	0.1	0.6
Long-standing illness, disability or infirmity	0.5	0.8	3.2	0.8	-1.2	1.2	1.8	0.7	0.6	-1.0	0.1	0.1	-0.2	0.7	-0.6	0.6	1.1	0.2	1.1
Ever had bowel cancer screening	3.3	3.8	6.3	1.8	0.9	2.2	1.3	1.7	1.9	1.6	2.5	-2.1	2.4	1.8	1.8	1.8	1.8	2.5	2.2
Diabetes diagnosed by doctor	2.0	3.3	12.1	-0.4	1.1	-2.1	-0.7	-0.9	-0.5	-0.4	-2.0	2.0	-1.4	-3.5	-1.0	-3.5	-0.9	-2.4	-2.1
Ever had stillbirth, spontaneous miscarriage or termination	1.3	1.4	2.4	1.3	0.0	1.5	1.5	1.0	1.4	0.3	1.3	-1.3	1.0	1.2	0.8	0.8	1.3	1.3	1.6
Friendships satisfaction	0.7	0.8	2.4	0.1	-1.4	0.2	0.8	0.0	-0.3	-1.6	-1.0	1.0	-1.2	-1.0	-1.5	-0.2	0.5	-1.0	0.2
Qualifications: nursing, teaching	1.1	1.7	5.1	-1.9	0.0	-1.8	-2.3	-1.4	-1.5	-0.5	-0.7	1.1	-0.6	-0.4	-0.6	-0.8	-2.0	-0.7	-1.8
Commuting to job workplace: Walk	0.3	0.3	1.2	-0.8	0.1	-0.4	-0.9	-0.6	-0.6	0.3	0.4	-0.4	0.3	1.1	0.5	0.6	-0.8	0.4	-0.4
Eye problems/disorders: Cataract	0.6	0.7	2.1	-1.1	-1.2	-0.4	-0.7	-1.2	-1.1	-1.4	-0.6	0.5	-0.7	0.9	-0.7	0.4	-0.8	-0.3	-0.3
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	1.5	1.2	0.5	1.0	1.1	1.0	1.0	0.6	0.5	-0.6	0.6	-0.3	0.5	0.1	1.2	0.4	0.9
Medication for cholesterol	2.5	3.7	6.3	-2.2	-0.4	-2.5	-2.2	-2.2	-2.2	-1.4	-1.9	1.9	-1.7	-0.9	-1.6	-1.7	-2.5	-1.9	-2.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.5	1.8	4.8	1.7	-0.4	2.1	1.6	1.5	1.5	0.2	1.0	-0.9	0.7	0.4	0.4	1.0	2.2	0.9	2.1
Back pain experienced in last month	2.2	3.2	11.5	-2.1	-3.4	-0.4	-1.0	-1.9	-2.4	-2.7	-1.3	1.5	-1.9	1.3	-2.3	1.1	-1.3	-0.8	-0.4
Mineral and other dietary supplements	0.9	1.2	1.6	1.1	0.6	1.2	0.7	1.0	1.1	1.1	1.3	-1.3	1.2	1.0	1.3	1.0	1.0	1.2	1.2
Breast cancer (self-reported)	0.4	0.5	2.4	-0.1	-1.6	0.3	0.6	-0.2	-0.3	-1.3	-0.5	0.3	-0.9	0.6	-1.0	-0.1	0.0	-0.4	0.3
Asthma (self-reported)	0.7	1.4	2.4	-1.0	-0.3	-1.3	-1.0	-0.9	-1.3	-1.1	-1.5	1.4	-1.4	-0.6	-1.0	-1.4	-1.0	-1.6	-1.4
Osteoporosis (self-reported)	0.0	0.1	0.1	0.2	-0.3	0.3	0.4	0.3	0.3	0.2	0.2	-0.1	0.2	0.3	-0.1	-0.2	0.1	0.2	0.3
Osteoarthritis (self-reported)	2.5	3.3	13.9	-1.6	-3.7	0.9	-0.6	-1.7	-2.0	-2.8	-0.0	0.3	-0.9	2.7	-1.8	2.8	-0.5	0.7	1.0
Medication: Aspirin	0.2	0.3	0.5	0.6	0.0	0.6	0.7	0.4	0.6	0.4	0.6	-0.4	0.5	0.4	0.6	0.6	0.6	0.6	0.6
Medication: Gliclazide	0.3	0.3	1.5	0.0	1.0	-0.5	-0.6	-0.1	0.1	0.2	-0.1	-0.0	0.1	-1.2	0.4	-1.2	-0.1	-0.4	-0.5
Illnesses of father: None of the above (group 1)	2.2	2.7	4.5	-1.9	-1.6	-1.4	-1.4	-1.9	-1.6	-2.1	-1.8	1.9	-1.8	-0.5	-2.0	-0.2	-1.6	-1.6	-1.4
Smoking status: Current	0.7	1.1	4.5	0.4	-0.7	-0.3	1.0	-0.0	0.3	-1.0	-1.4	1.3	-1.4	-1.3	-1.1	-2.1	0.4	-1.6	-0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.3	2.7	7.8	-0.7	1.4	-2.4	-1.2	-0.8	-0.4	0.2	-1.7	1.7	-1.0	-2.6	-0.4	-2.8	-1.4	-2.0	-2.4
Whole body water mass	3.2	18.4	58.7	2.7	-3.1	6.0	4.5	2.1	2.4	-0.3	4.0	-4.0	2.6	6.0	1.1	7.7	4.1	4.8	6.1
Leg predicted mass (right)	2.3	12.5	42.5	1.9	-3.5	5.1	3.8	1.5	1.6	-1.1	2.9	-2.9	1.6	5.1	0.2	6.5	3.4	3.7	5.1
Arm fat mass (left)	0.5	1.9	7.0	0.7	-2.6	1.9	2.0	0.5	0.3	-1.7	0.0	-0.0	-0.6	1.0	-1.0	1.8	1.5	0.4	1.9
Number of self-reported non-cancer illnesses	0.1	0.1	0.4	0.2	-0.6	0.3	0.6	0.2	0.2	-0.6	-0.4	0.4	-0.4	-0.1	-0.5	-0.1	0.4	-0.3	0.2
Average weekly champagne plus white wine intake	0.2	0.2	0.9	-0.2	-0.8	0.5	-0.0	0.3	-0.2	-0.1	0.4	-0.6	0.1	0.8	0.1	0.9	0.0	0.4	0.4
Miserableness	0.2	0.4	1.1	-0.5	1.0	-0.8	-1.0	-0.4	-0.4	1.0	0.2	-0.1	0.4	0.1	0.6	-0.1	-0.8	0.1	-0.8
Guilty feelings	0.3	0.5	1.1	-0.9	-0.7	-0.6	-0.7	-0.8	-0.8	-0.7	-0.4	0.8	-0.5	1.0	-0.6	0.0	-0.9	-0.3	-0.6
Wears glasses or contact lenses	1.6	1.9	3.1	-1.4	-0.9	-1.5	-0.9	-1.7	-1.8	-1.2	-1.4	1.5	-1.4	-1.0	-1.3	-0.8	-1.5	-1.3	-1.5
Ever taken oral contraceptive pill	0.7	0.7	1.4	-1.2	-1.0	-0.8	-1.0	-0.9	-1.2	-1.1	-0.7	0.8	-0.9	-0.1	-0.7	-0.1	-1.0	-0.6	-0.8
Hearing aid user	0.7	0.8	1.9	-1.4	-0.8	-0.6	-1.3	-1.4	-1.1	-1.2	-0.3	0.7	-0.6	0.6	-1.1	0.4	-1.1	-0.2	-0.6
Mother’s age at death	0.6	0.7	1.8	-1.1	-0.4	-0.9	-1.0	-1.3	-1.1	-0.6	-0.6	0.7	-0.6	-0.3	-0.9	0.1	-1.1	-0.6	-1.0
Financial situation satisfaction	0.2	0.3	0.9	-0.2	0.0	-0.7	-0.2	-0.3	-0.6	-0.2	-0.7	0.4	-0.5	-0.8	0.0	-0.9	-0.3	-0.7	-0.6
Tinnitus: Yes, now most or all of the time	1.9	2.2	4.6	0.9	0.7	1.6	0.3	1.2	1.0	1.1	2.1	-1.4	1.8	1.9	1.2	2.2	1.1	2.1	1.6
Commuting to job workplace: Public transport	1.2	1.4	2.4	0.9	1.0	0.9	0.7	1.0	1.0	1.4	1.4	-1.5	1.4	1.1	1.6	1.3	0.8	1.3	0.9
Eye problems/disorders: Glaucoma	0.9	1.1	3.5	-0.4	-1.6	-0.2	0.2	-0.3	-0.2	-1.9	-1.4	1.5	-1.6	-0.3	-1.6	-0.8	-0.0	-1.3	-0.2
Medication: Blood pressure	3.7	7.1	15.5	2.4	-1.3	3.9	3.1	2.3	2.3	0.6	2.5	-2.3	1.8	2.7	1.3	3.5	3.2	2.9	3.9
Pain type(s) experienced in last month: Hip pain	0.8	1.0	4.1	0.6	-2.0	1.1	1.6	0.6	0.2	-1.5	-0.6	0.8	-0.9	0.2	-1.1	0.5	1.0	-0.3	1.1
Supplements: Fish oil (including cod liver oil)	0.4	0.6	1.2	-0.6	-0.3	-0.8	-0.3	-0.7	-0.6	-0.7	-0.9	1.1	-0.9	-0.7	-0.9	-0.8	-0.6	-0.9	-0.8
High cholesterol (Self-reported)	1.0	1.7	3.1	1.4	-0.1	1.8	1.6	1.6	1.5	0.7	1.3	-1.2	1.0	0.6	0.8	1.4	1.6	1.3	1.7
Medication: Bendroflumethiazide	2.7	4.1	8.5	1.7	-0.8	2.9	2.0	1.7	1.5	0.8	2.0	-2.3	1.4	1.7	1.6	2.7	2.3	2.3	2.9
Medication: Paracetamol	0.9	1.4	4.6	-0.5	-2.1	-0.1	0.4	-0.5	-0.8	-2.1	-1.5	1.3	-1.6	-0.3	-1.9	-0.6	0.0	-1.3	-0.1
Medication: Lisinopril	1.5	2.0	5.4	1.4	-1.8	2.2	2.3	1.3	0.8	-0.6	0.5	-0.3	0.1	1.2	-0.3	1.4	2.0	0.8	2.2
Medication: Atorvastatin	1.8	2.2	5.2	-2.0	-1.8	-1.1	-1.5	-2.3	-2.0	-2.0	-1.1	1.2	-1.3	0.5	-1.7	0.4	-1.6	-0.8	-1.1
Illnesses of father: High blood pressure	2.4	3.0	4.5	1.6	0.3	2.0	1.6	1.2	1.3	1.6	2.1	-2.1	1.7	1.8	2.0	1.9	1.6	2.0	2.0
Alcohol drinker status: Never	0.2	0.3	1.6	0.2	0.6	-0.4	-0.0	-0.0	0.4	-0.3	-0.6	0.6	-0.4	-1.2	-0.6	-0.8	0.0	-0.6	-0.4
Ever smoked	0.4	0.7	2.3	-0.8	-1.3	-0.3	-0.4	-1.0	-1.0	-1.5	-0.8	0.9	-1.0	0.2	-1.1	0.2	-0.4	-0.7	-0.2
Basal metabolic rate	3.0	16.4	51.6	2.6	-3.3	5.8	4.4	2.1	2.2	-0.6	3.6	-3.6	2.2	5.5	0.8	7.2	4.0	4.4	5.8
Leg fat percentage (left)	0.1	0.5	1.6	-0.1	-1.3	0.1	0.5	0.0	-0.4	-1.2	-0.8	0.8	-0.9	-0.5	-1.0	-0.2	0.2	-0.6	0.1
Arm fat-free mass (left)	2.6	13.1	42.8	2.2	-2.4	4.9	3.7	1.7	1.9	-0.0	3.5	-3.5	2.4	5.3	1.1	6.5	3.3	4.2	5.0
Number of operations (self-reported)	0.3	0.4	1.4	0.3	-1.1	0.6	1.2	0.4	0.3	-1.1	-0.3	0.4	-0.5	-0.0	-0.7	-0.0	0.6	-0.1	0.6
Average weekly beer plus cider intake	0.4	0.6	1.2	-0.4	-0.7	-0.5	0.1	-0.7	-0.4	-1.0	-1.1	1.0	-1.1	-0.8	-1.0	-1.0	-0.4	-1.0	-0.5
Irritability	0.1	0.1	0.5	0.5	0.1	0.4	0.6	0.7	0.5	0.2	0.1	-0.0	0.1	0.4	-0.2	-0.0	0.6	0.1	0.4
Risk taking	0.1	0.1	0.6	0.2	-0.8	0.4	0.6	0.0	0.0	-0.5	-0.1	-0.2	-0.2	0.4	-0.2	0.3	0.3	0.1	0.5
Ever had prostate specific antigen (PSA) test	1.1	1.2	3.5	-1.7	-1.1	-0.7	-1.7	-1.6	-1.9	-0.7	0.0	0.1	-0.4	0.9	-0.6	1.0	-1.6	0.2	-0.7
Fractured/broken bones in last 5 years	0.3	0.4	2.0	0.4	-1.4	0.7	0.9	0.3	0.0	-1.0	-0.3	0.3	-0.4	0.0	-0.9	-0.5	0.7	-0.2	0.7
Age started oral contraceptive pill	0.1	0.2	0.5	0.6	0.3	0.4	0.6	0.7	0.4	0.6	0.2	-0.3	0.5	-0.2	0.4	-0.0	0.5	0.2	0.3
Diastolic blood pressure, automated reading	0.3	0.8	1.9	1.0	-0.4	1.4	1.3	1.0	0.7	0.4	0.6	-0.7	0.4	0.4	0.4	1.0	1.2	0.8	1.4
Ever depressed for a whole week	0.3	0.3	0.6	-0.7	-0.7	-0.5	-0.3	-0.5	-0.5	-0.8	-0.7	0.7	-0.8	-0.3	-0.6	-0.2	-0.5	-0.6	-0.5
Unable to work because of sickness or disability	0.2	0.2	0.7	0.4	-0.7	0.6	0.8	-0.1	0.1	-0.5	0.1	-0.2	-0.1	0.8	-0.2	-0.2	0.5	0.2	0.6
Commuting to job workplace: Cycle	0.1	0.1	0.2	-0.1	-0.3	-0.2	-0.1	-0.2	-0.2	-0.4	-0.3	0.3	-0.4	-0.3	-0.4	0.0	-0.1	-0.4	-0.2
Myopia	1.0	1.4	2.4	1.4	0.8	1.4	1.1	1.0	1.5	1.1	1.2	-1.2	1.4	0.0	1.0	0.5	1.5	1.2	1.4
Vascular/heart problems diagnosed by doctor	2.6	7.2	12.9	-2.4	0.1	-3.5	-2.7	-2.4	-2.2	-1.7	-2.9	2.8	-2.3	-2.6	-2.3	-3.6	-2.9	-3.1	-3.5
Cholesterol lowering medication	0.5	0.7	1.2	0.8	0.8	0.7	0.6	0.8	0.8	1.0	1.0	-0.8	1.1	0.3	1.1	0.7	0.7	1.0	0.7
Medication: Omeprazole (e.g. Zanprol)	1.9	2.3	5.7	-0.2	-0.9	-1.0	0.7	-0.7	-0.4	-1.6	-2.1	1.9	-1.9	-2.4	-1.9	-2.2	-0.2	-2.1	-1.0
Pain experienced in last month	0.8	1.3	6.6	0.2	2.6	-1.1	-0.8	0.2	0.5	1.9	0.1	-0.4	0.7	-1.4	1.2	-1.8	-0.4	-0.4	-1.2
Supplements: Calcium	0.4	0.4	1.2	0.6	-1.0	0.8	1.1	0.5	0.7	-0.9	-0.1	0.3	-0.4	-0.5	-0.7	-0.3	0.8	-0.1	0.8
Basal cell carcinoma (self-reported)	1.2	1.4	3.1	-1.5	-0.1	-1.4	-1.8	-1.6	-1.6	-0.9	-0.8	1.1	-0.7	-0.5	-0.8	-0.8	-1.5	-0.8	-1.4
Heart attack/myocardial infarction (self-reported)	1.0	1.3	5.2	1.9	0.2	1.2	2.3	1.6	1.5	0.3	0.2	-0.1	0.3	-0.8	0.2	-0.4	1.8	0.1	1.2
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	1.5	1.1	0.3	1.2	1.1	1.1	1.0	0.8	1.1	-1.2	1.1	0.8	0.9	0.9	1.1	1.1	1.2
Heart disease (siblings)	1.1	1.3	4.4	1.7	0.2	1.3	2.1	1.5	1.4	0.8	0.7	-0.4	0.7	0.6	0.7	-0.0	1.6	0.5	1.3
Alcohol drinker status: Previous	2.0	2.3	4.6	2.1	1.4	1.4	1.6	1.7	2.1	1.7	1.3	-1.5	1.4	0.2	1.5	0.1	1.8	1.1	1.4
Pack years of smoking	0.6	0.9	5.0	-0.1	-2.2	0.4	1.2	-0.3	-0.5	-1.6	-0.9	0.8	-1.4	0.2	-1.1	-0.1	0.2	-0.7	0.4
Impedance of whole body	0.4	2.1	11.8	0.4	1.3	-1.3	-0.3	0.7	0.5	0.6	-1.2	1.0	-0.8	-3.1	-0.0	-3.4	-0.2	-1.7	-1.3
Leg fat mass (left)	0.5	2.0	6.1	0.8	-2.5	2.1	2.1	0.7	0.4	-1.5	0.3	-0.3	-0.3	1.2	-0.8	2.0	1.6	0.7	2.1
Arm predicted mass (left)	2.8	14.2	44.4	2.5	-2.4	5.2	4.0	2.0	2.2	0.0	3.6	-3.6	2.4	5.3	1.1	6.7	3.6	4.2	5.3