[Hub]/) : Traits : Worrier / anxious feelings : →

chr3:49,598,064-51,234,774

Best TWAS P=1.8e-10 · Best GWAS P=5.18e-08 conditioned to 0.582

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous HYAL1 0.09 0.06 lasso 1 0.05 4.3e-05 5.2 5.2 2.0e-07 0.93 0.01 0.98 FALSE
2 GTEx Artery Aorta SEMA3B-AS1 0.67 0.00 enet 61 0.12 5.0e-07 1.1 6.4 1.8e-10 0.31 0.07 0.45 TRUE
3 GTEx Cells Transformed fibroblasts SEMA3B-AS1 0.15 0.01 enet 3 0.00 3.9e-01 5.1 5.4 7.3e-08 0.98 0.02 0.95 FALSE
4 GTEx Esophagus Gastroesophageal Junction HYAL1 0.30 0.13 lasso 9 0.10 2.1e-04 5.2 5.3 1.0e-07 0.95 0.01 0.97 FALSE
5 GTEx Esophagus Muscularis HYAL1 0.11 0.08 lasso 5 0.05 3.3e-04 5.2 5.3 1.1e-07 0.96 0.01 0.98 FALSE
6 GTEx Muscle Skeletal HYAL1 0.08 0.08 lasso 3 0.06 7.6e-07 5.2 5.2 1.7e-07 0.96 0.01 0.99 FALSE
7 GTEx Nerve Tibial U73166.2 0.07 0.03 lasso 3 0.03 2.8e-03 5.3 -5.2 1.6e-07 -0.95 0.01 0.97 FALSE
8 METSIM Adipose CYB561D2 0.09 0.08 lasso 5 0.07 3.8e-10 5.2 -5.4 8.2e-08 -0.94 0.02 0.98 TRUE
9 ROSMAP Brain Pre-frontal Cortex CACNA2D2 0.05 0.02 lasso 3 0.02 3.6e-03 5.2 -5.3 1.4e-07 -0.96 0.01 0.97 FALSE
10 ROSMAP Brain Pre-frontal Cortex SEMA3B 0.05 0.03 lasso 6 0.02 8.3e-04 5.2 5.3 9.4e-08 0.97 0.01 0.99 FALSE
11 The Cancer Genome Atlas Pancreatic Adenocarcinoma C3orf45 0.07 0.05 enet 4 0.05 2.9e-03 5.2 -5.1 2.7e-07 -0.88 0.00 0.88 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma HYAL1 0.04 0.00 blup 13 0.01 1.8e-02 5.2 5.2 1.6e-07 0.72 0.00 0.78 FALSE