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chr2:102,118,712-103,767,612

Best TWAS P=8.05e-23 · Best GWAS P=1.58e-17 conditioned to 0.126

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
13	The Cancer Genome Atlas	Lung Adenocarcinoma	IL1RL1	0.03	0.01	blup	78	0.02	4.7e-03	-7.7	-9.8	8.1e-23	0.77	0.02	0.88	TRUE
8	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	IL1RL1	0.04	0.04	lasso	8	0.04	1.7e-05	-8.5	-9.5	1.7e-21	0.78	0.02	0.96	FALSE
10	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	IL1RL1	0.08	0.08	enet	9	0.08	1.2e-09	-8.3	-9.1	6.1e-20	0.71	0.01	0.99	FALSE
12	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	IL1RL1	0.18	0.06	blup	78	0.15	3.7e-09	7.3	-9.0	2.0e-19	0.64	0.03	0.97	FALSE
14	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	IL1RL1	0.19	0.05	blup	78	0.10	7.1e-05	7.5	-9.0	3.1e-19	0.68	0.06	0.84	FALSE
9	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	IL18RAP	0.03	0.02	blup	94	0.02	1.2e-03	-8.3	8.6	9.6e-18	-0.71	0.00	0.93	FALSE
15	The Cancer Genome Atlas	Thyroid Carcinoma	IL1RL1	0.05	0.03	enet	6	0.03	9.7e-04	-8.3	-8.3	1.2e-16	0.66	0.02	0.98	FALSE
5	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	IL1RL1	0.04	0.03	lasso	7	0.03	8.1e-04	-8.2	-7.7	1.0e-14	0.67	0.02	0.92	FALSE
7	The Cancer Genome Atlas	Breast Invasive Carcinoma	IL1RL1	0.02	0.01	blup	78	0.01	1.5e-03	7.3	-7.5	6.3e-14	0.61	0.10	0.48	FALSE
11	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	IL1RL2	0.04	0.04	enet	5	0.03	1.9e-04	-6.7	-6.9	6.9e-12	0.39	0.06	0.42	FALSE
1	GTEx	Colon Transverse	IL18R1	0.14	0.00	enet	41	0.00	2.1e-01	3.4	6.5	8.7e-11	-0.33	0.06	0.27	FALSE
3	ROSMAP	Brain Pre-frontal Cortex	IL1RL2	0.08	0.02	enet	33	0.03	2.3e-04	3.4	-6.1	1.2e-09	0.27	0.19	0.10	FALSE
6	The Cancer Genome Atlas	Breast Invasive Carcinoma	IL18R1	0.05	0.01	blup	108	0.03	1.8e-07	-8.3	5.7	1.1e-08	-0.43	0.02	0.98	FALSE
2	GTEx	Whole Blood	IL18R1	0.06	0.00	enet	14	0.01	2.1e-02	-8.2	5.5	4.0e-08	-0.51	0.04	0.80	FALSE
4	YFS	Blood	IL18RAP	0.41	0.55	bslmm	562	0.62	4.2e-269	7.0	-5.2	2.5e-07	0.46	1.00	0.00	FALSE