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chr4:87,655,053-89,898,476

Best TWAS P=8.85e-117 · Best GWAS P=5.74e-174 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
9	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ABCG2	0.04	0.02	blup	100	0.04	1.8e-05	15.49	23.0	8.8e-117	0.53	0.23	0.50	TRUE
5	NTR	Blood	PPM1K	0.02	0.00	blup	468	0.00	1.8e-02	5.78	-10.6	4.0e-26	-0.43	0.06	0.39	TRUE
4	METSIM	Adipose	ABCG2	0.05	0.01	bslmm	512	0.01	2.9e-03	-5.42	9.8	1.5e-22	0.24	0.17	0.04	TRUE
12	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	ABCG2	0.11	0.03	lasso	4	0.05	2.6e-04	8.41	8.3	1.5e-16	0.13	0.27	0.04	TRUE
15	The Cancer Genome Atlas	Prostate Adenocarcinoma	PPM1K	0.13	0.11	enet	6	0.14	8.8e-15	-6.37	-7.0	2.4e-12	-0.09	1.00	0.00	TRUE
11	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	PPM1K	0.08	0.03	blup	57	0.05	2.8e-03	-5.22	-6.8	9.6e-12	-0.13	0.36	0.07	TRUE
14	The Cancer Genome Atlas	Prostate Adenocarcinoma	HERC6	0.04	0.00	blup	46	0.00	2.9e-01	5.25	-6.7	2.8e-11	-0.08	0.01	0.10	TRUE
3	GTEx	Testis	PKD2	0.45	0.48	lasso	6	0.47	2.1e-23	-5.82	-6.0	2.2e-09	-0.20	1.00	0.00	TRUE
2	GTEx	Brain Cerebellar Hemisphere	NUDT9	0.28	0.00	enet	29	0.19	1.1e-05	-0.98	-5.8	8.7e-09	-0.18	0.06	0.25	TRUE
7	The Cancer Genome Atlas	Breast Invasive Carcinoma	PPM1K	0.04	0.05	lasso	3	0.04	5.4e-09	-5.37	-5.7	1.6e-08	-0.10	1.00	0.00	TRUE
13	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	SPP1	0.14	0.03	blup	64	0.07	1.0e-03	5.66	5.6	2.1e-08	0.18	0.04	0.04	TRUE
6	ROSMAP	Brain Pre-frontal Cortex	PKD2	0.11	0.09	lasso	13	0.11	3.3e-14	4.97	5.4	5.6e-08	0.20	1.00	0.00	TRUE
10	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PKD2	0.07	0.01	blup	84	0.02	2.0e-03	18.68	-15.4	9.0e-54	-0.43	0.07	0.17	FALSE
8	The Cancer Genome Atlas	Breast Invasive Carcinoma	SPP1	0.04	0.00	enet	11	0.01	3.3e-03	-4.46	-8.3	7.4e-17	-0.28	0.04	0.51	FALSE
1	CommonMind	Brain Pre-frontal Cortex	PKD2	0.17	0.10	enet	15	0.16	2.1e-18	-6.13	-5.6	2.1e-08	-0.15	1.00	0.00	FALSE