[Hub]/) : Traits : Sitting height : ← →

chr6:79,646,575-84,576,263

Best TWAS P=1.01e-67 · Best GWAS P=2.9e-86 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	BCKDHB	0.11	0.09	bslmm	563	0.09	1.1e-10	11.33	9.4	3.6e-21	-0.32	1.00	0.00	FALSE
2	CommonMind	Brain Pre-frontal Cortex	TTK	0.07	0.00	bslmm	472	0.02	3.8e-03	-0.53	-5.7	1.2e-08	0.21	0.13	0.05	FALSE
3	GTEx	Adipose Subcutaneous	RP11-250B2.6	0.07	0.04	lasso	4	0.05	4.4e-05	10.42	-6.6	4.6e-11	0.26	0.64	0.06	FALSE
4	GTEx	Adipose Visceral Omentum	RP11-250B2.3	0.13	0.00	enet	13	0.01	8.2e-02	-8.43	-6.4	1.7e-10	0.23	0.06	0.12	FALSE
5	GTEx	Adipose Visceral Omentum	RP11-250B2.6	0.16	0.05	lasso	6	0.06	7.8e-04	16.34	-17.0	4.0e-65	0.55	0.01	0.97	FALSE
6	GTEx	Artery Aorta	BCKDHB	0.14	0.14	lasso	1	0.13	9.8e-08	11.36	11.4	6.4e-30	-0.28	0.99	0.00	FALSE
7	GTEx	Artery Aorta	ELOVL4	0.11	0.13	lasso	2	0.11	1.7e-06	9.76	9.7	5.0e-22	-0.39	0.93	0.02	TRUE
8	GTEx	Artery Coronary	BCKDHB	0.29	0.05	lasso	27	0.11	1.7e-04	11.33	11.8	5.6e-32	-0.23	0.40	0.06	TRUE
9	GTEx	Artery Tibial	BCKDHB	0.16	0.16	lasso	11	0.15	4.9e-12	11.31	10.8	2.2e-27	-0.28	1.00	0.00	FALSE
10	GTEx	Artery Tibial	ELOVL4	0.13	0.12	lasso	8	0.10	2.0e-08	8.88	8.6	6.1e-18	-0.40	1.00	0.00	FALSE
11	GTEx	Brain Caudate basal ganglia	BCKDHB	0.21	-0.01	enet	53	0.00	4.5e-01	-17.21	8.6	1.1e-17	-0.42	0.05	0.48	FALSE
12	GTEx	Brain Cerebellar Hemisphere	RP11-250B2.3	0.30	0.05	enet	32	0.12	5.2e-04	-17.21	-7.4	1.8e-13	0.47	0.01	0.90	FALSE
13	GTEx	Brain Cerebellum	RP11-250B2.5	0.43	0.11	lasso	5	0.14	4.7e-05	-17.67	-14.5	1.5e-47	0.53	0.00	0.99	FALSE
14	GTEx	Breast Mammary Tissue	RP11-250B2.3	0.13	0.06	lasso	4	0.04	2.6e-03	-8.43	-9.4	4.4e-21	0.34	0.03	0.83	FALSE
15	GTEx	Breast Mammary Tissue	RP11-250B2.5	0.13	0.11	enet	16	0.08	5.1e-05	-6.21	-5.7	1.6e-08	0.27	0.04	0.94	FALSE
16	GTEx	Breast Mammary Tissue	RP11-250B2.6	0.12	0.02	enet	9	0.03	1.7e-02	10.44	-6.1	8.2e-10	0.22	0.25	0.22	FALSE
17	GTEx	Breast Mammary Tissue (Male)	RP11-250B2.5	0.12	0.09	lasso	4	0.08	7.5e-03	-6.21	-5.3	1.4e-07	0.19	0.06	0.29	FALSE
18	GTEx	Breast Mammary Tissue (Female)	RP11-250B2.3	0.16	0.06	enet	11	0.04	2.4e-02	15.81	-12.0	2.3e-33	0.49	0.03	0.76	FALSE
19	GTEx	Breast Mammary Tissue (Female)	RP11-250B2.5	0.08	-0.01	lasso	4	-0.01	7.0e-01	-16.38	-9.2	5.0e-20	0.31	0.03	0.53	FALSE
20	GTEx	Cells EBV-transformed lymphocytes	BCKDHB	0.15	0.11	enet	34	0.07	3.1e-03	10.43	5.3	1.1e-07	-0.33	0.30	0.27	FALSE
21	GTEx	Cells EBV-transformed lymphocytes	RP11-250B2.6	0.21	0.03	enet	37	0.13	4.7e-05	11.33	-8.6	1.0e-17	0.14	0.11	0.28	FALSE
22	GTEx	Cells Transformed fibroblasts	BCKDHB	0.16	0.02	enet	42	0.04	3.7e-04	10.34	16.1	1.3e-58	-0.55	0.49	0.29	TRUE
23	GTEx	Cells Transformed fibroblasts	ELOVL4	0.09	0.05	lasso	7	0.06	2.8e-05	7.63	6.6	3.4e-11	-0.25	0.32	0.04	FALSE
24	GTEx	Cells Transformed fibroblasts	RP11-250B2.6	0.11	0.01	lasso	7	0.00	1.4e-01	-17.04	-13.2	6.2e-40	0.57	0.02	0.95	FALSE
25	GTEx	Colon Transverse	RP11-250B2.5	0.13	0.02	enet	3	0.01	6.3e-02	-8.43	-14.1	5.3e-45	0.50	0.02	0.82	TRUE
26	GTEx	Colon Transverse	RP11-250B2.6	0.15	0.16	lasso	2	0.13	9.8e-07	10.34	-9.7	2.3e-22	0.27	0.94	0.02	FALSE
27	GTEx	Esophagus Mucosa	BCKDHB	0.17	0.16	lasso	6	0.15	3.9e-10	9.25	-7.9	2.4e-15	0.37	1.00	0.00	FALSE
28	GTEx	Esophagus Mucosa	RP11-250B2.6	0.20	0.16	lasso	7	0.23	3.3e-15	-17.04	-17.4	1.7e-67	0.65	0.02	0.98	TRUE
29	GTEx	Esophagus Muscularis	BCKDHB	0.18	0.07	enet	25	0.06	2.4e-04	11.33	10.3	5.7e-25	-0.28	0.93	0.02	TRUE
30	GTEx	Esophagus Muscularis	ELOVL4	0.16	0.05	enet	18	0.11	3.4e-07	9.88	7.6	3.9e-14	-0.30	0.91	0.01	FALSE
31	GTEx	Esophagus Muscularis	RP11-250B2.5	0.16	0.00	lasso	6	0.00	4.4e-01	9.72	-7.4	1.2e-13	0.38	0.07	0.21	FALSE
32	GTEx	Heart Atrial Appendage	RP11-250B2.6	0.20	0.00	enet	17	0.03	2.6e-02	-6.25	-17.0	3.5e-65	0.32	0.07	0.30	TRUE
33	GTEx	Heart Left Ventricle	RP11-250B2.6	0.09	0.00	enet	6	0.02	2.0e-02	16.11	-16.0	1.2e-57	0.59	0.06	0.64	FALSE
34	GTEx	Lung	BCKDHB	0.09	0.06	enet	10	0.05	1.8e-04	11.34	11.3	8.0e-30	-0.28	0.81	0.12	FALSE
35	GTEx	Lung	RP11-250B2.6	0.09	0.05	enet	16	0.07	5.3e-06	10.44	-15.6	1.6e-54	0.38	0.57	0.34	FALSE
36	GTEx	Muscle Skeletal	RP11-250B2.6	0.07	0.04	lasso	5	0.04	4.2e-05	16.93	-17.4	1.0e-67	0.67	0.63	0.34	FALSE
37	GTEx	Nerve Tibial	BCKDHB	0.18	0.11	lasso	9	0.10	2.4e-07	11.33	11.3	1.6e-29	-0.28	1.00	0.00	FALSE
38	GTEx	Nerve Tibial	SH3BGRL2	0.18	0.02	lasso	5	0.04	1.4e-03	9.84	6.2	7.4e-10	-0.29	0.27	0.12	FALSE
39	GTEx	Nerve Tibial	RP11-250B2.5	0.22	0.08	lasso	6	0.08	2.6e-06	1.06	-7.5	8.4e-14	0.39	0.12	0.88	FALSE
40	GTEx	Nerve Tibial	RP11-250B2.6	0.13	0.09	enet	10	0.09	8.7e-07	3.62	-6.0	1.7e-09	0.31	0.99	0.00	FALSE
41	GTEx	Pancreas	BCKDHB	0.14	0.08	enet	6	0.05	3.8e-03	4.08	7.2	4.2e-13	-0.26	0.40	0.16	FALSE
42	GTEx	Skin Not Sun Exposed Suprapubic	RP11-250B2.3	0.12	0.11	lasso	4	0.15	1.1e-08	15.81	-8.2	2.3e-16	0.31	0.37	0.57	FALSE
43	GTEx	Skin Not Sun Exposed Suprapubic	RP11-250B2.5	0.13	0.16	lasso	4	0.17	1.1e-09	15.81	-12.0	2.5e-33	0.48	0.28	0.71	FALSE
44	GTEx	Skin Not Sun Exposed Suprapubic	RP11-250B2.6	0.08	0.05	lasso	4	0.01	8.1e-02	10.43	-10.2	2.0e-24	0.25	0.20	0.16	FALSE
45	GTEx	Skin Sun Exposed Lower leg	RP11-250B2.3	0.12	0.06	enet	29	0.07	2.5e-06	15.81	-11.5	8.7e-31	0.54	0.14	0.86	FALSE
46	GTEx	Skin Sun Exposed Lower leg	RP11-250B2.5	0.09	0.03	enet	34	0.06	4.6e-06	17.57	-10.5	6.1e-26	0.49	0.01	0.99	FALSE
47	GTEx	Stomach	RP11-250B2.3	0.12	-0.01	lasso	8	0.00	1.9e-01	1.06	-5.8	5.5e-09	0.27	0.09	0.15	FALSE
48	GTEx	Stomach	RP11-250B2.6	0.13	0.15	lasso	6	0.12	2.5e-06	10.34	-9.5	1.4e-21	0.25	0.79	0.16	FALSE
49	GTEx	Testis	ELOVL4	0.31	0.19	lasso	7	0.18	1.9e-08	-6.05	-5.2	1.7e-07	0.13	0.96	0.00	TRUE
50	GTEx	Testis	RP11-250B2.5	0.13	0.17	lasso	3	0.14	7.0e-07	-16.99	-16.7	9.1e-63	0.72	0.03	0.97	FALSE
51	GTEx	Testis	RP11-250B2.6	0.09	0.05	lasso	6	0.04	6.9e-03	10.43	-9.7	2.9e-22	0.29	0.40	0.06	FALSE
52	GTEx	Thyroid	BCKDHB	0.17	0.06	lasso	8	0.10	3.4e-08	10.43	14.3	1.2e-46	-0.50	0.76	0.24	TRUE
53	GTEx	Thyroid	RP11-250B2.6	0.11	0.10	lasso	2	0.07	3.2e-06	10.34	-10.3	4.4e-25	0.27	1.00	0.00	FALSE
54	METSIM	Adipose	BCKDHB	0.05	0.03	blup	558	0.05	1.1e-07	-16.99	12.1	6.3e-34	-0.54	1.00	0.00	FALSE
55	METSIM	Adipose	DOPEY1	0.08	0.08	lasso	10	0.07	2.4e-10	4.63	-5.2	1.6e-07	0.01	0.27	0.73	FALSE
56	METSIM	Adipose	ELOVL4	0.06	0.03	bslmm	500	0.04	3.2e-06	8.93	9.6	8.0e-22	-0.42	1.00	0.00	FALSE
57	METSIM	Adipose	RP11-250B2.6	0.04	0.04	lasso	12	0.02	1.7e-04	17.57	-16.1	1.5e-58	0.61	0.73	0.02	TRUE
58	ROSMAP	Brain Pre-frontal Cortex	BCKDHB	0.18	0.13	lasso	6	0.14	2.9e-17	11.33	10.0	1.8e-23	-0.31	1.00	0.00	FALSE
59	ROSMAP	Brain Pre-frontal Cortex	FAM46A	0.08	0.01	blup	495	0.03	2.7e-04	3.97	5.1	2.8e-07	-0.01	0.65	0.01	TRUE
60	ROSMAP	Brain Pre-frontal Cortex	RP11-250B2.3	0.08	0.02	blup	402	0.04	5.8e-06	4.41	-9.2	2.7e-20	0.22	0.79	0.02	FALSE
61	YFS	Blood	BCKDHB	0.01	0.01	blup	557	0.00	1.3e-02	10.74	8.7	5.3e-18	-0.44	0.28	0.13	FALSE
62	YFS	Blood	DOPEY1	0.18	0.21	lasso	9	0.21	1.4e-67	4.63	-5.2	2.1e-07	0.03	0.82	0.18	FALSE
63	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	BCKDHB	0.12	0.06	lasso	4	0.06	4.2e-07	14.72	-12.7	6.7e-37	0.45	0.98	0.00	FALSE
64	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DOPEY1	0.08	0.08	blup	47	0.09	2.3e-10	4.63	-5.5	4.3e-08	0.04	0.03	0.97	FALSE
65	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ELOVL4	0.09	0.04	enet	4	0.02	1.9e-03	9.93	9.9	2.7e-23	-0.47	0.00	1.00	FALSE
66	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	DOPEY1	0.06	0.08	lasso	2	0.04	3.9e-03	6.19	-6.2	6.4e-10	0.01	0.00	0.94	TRUE
67	The Cancer Genome Atlas	Testicular Germ Cell Tumors	BCKDHB	0.19	0.02	blup	137	0.06	2.6e-03	11.30	7.2	4.1e-13	-0.13	0.03	0.05	FALSE