[Hub]/) : Traits : Mean time to correctly identify matches :

chr5:111,499,732-112,950,045

Best TWAS P=1.16e-10 · Best GWAS P=1.97e-10 conditioned to 0.0892

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SRP19 0.08 0.06 lasso 5 0.07 1.3e-08 5.0 -5.4 6.6e-08 -0.70 0.34 0.66 FALSE
2 GTEx Adipose Visceral Omentum REEP5 0.09 0.05 lasso 5 0.02 4.9e-02 5.8 5.6 2.2e-08 0.69 0.10 0.75 FALSE
3 GTEx Artery Aorta REEP5 0.17 0.07 lasso 13 0.10 4.2e-06 6.2 6.4 1.2e-10 0.85 0.05 0.95 TRUE
4 GTEx Artery Tibial REEP5 0.17 0.12 lasso 5 0.13 3.0e-10 5.5 5.1 2.7e-07 0.63 0.63 0.37 FALSE
5 GTEx Cells Transformed fibroblasts CTC-487M23.5 0.07 0.03 lasso 3 0.03 2.9e-03 -6.1 -6.0 1.5e-09 -0.82 0.04 0.88 FALSE
6 GTEx Colon Transverse REEP5 0.12 0.14 lasso 2 0.14 4.4e-07 5.7 5.7 1.2e-08 0.72 0.26 0.73 FALSE
7 GTEx Esophagus Gastroesophageal Junction REEP5 0.18 0.03 lasso 3 0.03 3.7e-02 5.5 5.5 4.4e-08 0.81 0.04 0.88 FALSE
8 GTEx Esophagus Mucosa REEP5 0.19 0.10 lasso 5 0.09 1.5e-06 5.5 5.3 1.3e-07 0.75 0.15 0.80 FALSE
9 GTEx Esophagus Muscularis REEP5 0.18 0.09 lasso 4 0.14 5.9e-09 5.7 5.7 1.2e-08 0.75 0.27 0.73 FALSE
10 GTEx Nerve Tibial REEP5 0.16 0.13 lasso 3 0.10 9.2e-08 5.5 5.3 9.9e-08 0.64 0.60 0.40 FALSE
11 GTEx Nerve Tibial XBP1P1 0.06 0.05 lasso 2 0.04 6.1e-04 4.9 5.7 1.2e-08 0.87 0.06 0.88 FALSE
12 GTEx Skin Not Sun Exposed Suprapubic CTC-487M23.5 0.10 0.06 lasso 3 0.05 6.7e-04 5.6 5.9 3.7e-09 0.73 0.12 0.69 FALSE
13 GTEx Skin Not Sun Exposed Suprapubic CTC-487M23.7 0.08 0.09 enet 7 0.10 3.9e-06 5.6 6.0 1.7e-09 0.80 0.14 0.82 FALSE
14 GTEx Skin Sun Exposed Lower leg REEP5 0.08 0.05 lasso 4 0.03 1.9e-03 4.7 5.2 2.5e-07 0.69 0.33 0.64 FALSE
15 GTEx Skin Sun Exposed Lower leg CTC-487M23.5 0.17 0.07 lasso 6 0.06 7.7e-06 5.6 5.8 6.2e-09 0.69 0.30 0.70 FALSE
16 GTEx Skin Sun Exposed Lower leg CTC-487M23.7 0.06 0.07 lasso 1 0.04 2.4e-04 5.6 5.6 1.9e-08 0.64 0.14 0.82 FALSE
17 GTEx Testis REEP5 0.22 0.14 lasso 5 0.14 6.6e-07 5.7 6.0 1.7e-09 0.75 0.13 0.86 FALSE
18 NTR Blood REEP5 0.03 0.04 lasso 9 0.04 3.3e-12 6.2 6.3 2.7e-10 0.81 0.03 0.97 FALSE
19 The Cancer Genome Atlas Brain Lower Grade Glioma SRP19 0.05 0.04 lasso 3 0.04 3.7e-05 5.6 -5.6 2.8e-08 -0.69 0.15 0.83 FALSE
20 The Cancer Genome Atlas Prostate Adenocarcinoma SRP19 0.05 0.05 lasso 1 0.05 4.5e-06 5.5 -5.5 3.4e-08 -0.77 0.23 0.71 FALSE
21 The Cancer Genome Atlas Soft Tissue Sarcoma SRP19 0.07 0.03 lasso 4 0.02 2.4e-02 5.5 -5.5 4.8e-08 -0.77 0.05 0.33 FALSE
22 The Cancer Genome Atlas Stomach Adenocarcinoma REEP5 0.03 0.02 blup 47 0.03 4.1e-03 4.7 5.8 6.9e-09 0.75 0.04 0.40 FALSE
23 The Cancer Genome Atlas Thyroid Carcinoma APC 0.02 0.02 enet 5 0.02 4.2e-03 -6.2 6.4 1.7e-10 0.91 0.03 0.87 FALSE