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chr9:126,927,285-129,422,783

Best TWAS P=8.46e-10 · Best GWAS P=4.55e-08 conditioned to 0.781

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Brain Cerebellum	PRPS1P2	0.09	0.08	enet	16	0.04	2.8e-02	4.0	-5.5	3.4e-08	0.85	0.06	0.74	FALSE
2	GTEx	Cells Transformed fibroblasts	PBX3	0.05	0.02	enet	7	0.00	1.4e-01	4.5	-5.2	2.4e-07	0.16	0.09	0.78	FALSE
3	GTEx	Nerve Tibial	PRPS1P2	0.11	0.11	enet	9	0.10	1.4e-07	-5.4	-5.5	4.1e-08	0.93	0.03	0.97	FALSE
4	GTEx	Skin Not Sun Exposed Suprapubic	PPP6C	0.08	0.06	lasso	4	0.05	7.8e-04	-5.4	5.4	6.1e-08	-0.99	0.02	0.95	FALSE
5	GTEx	Skin Sun Exposed Lower leg	RABEPK	0.07	0.05	lasso	4	0.05	6.3e-05	-5.5	5.4	7.1e-08	-0.98	0.02	0.98	FALSE
6	GTEx	Skin Sun Exposed Lower leg	GAPVD1	0.04	0.01	lasso	4	0.01	3.8e-02	-4.4	5.5	4.8e-08	-0.87	0.09	0.86	FALSE
7	GTEx	Spleen	PRPS1P2	0.18	0.02	lasso	4	0.04	3.9e-02	-5.5	-6.1	8.5e-10	0.91	0.05	0.53	TRUE
8	GTEx	Thyroid	ARPC5L	0.18	0.12	enet	17	0.16	1.5e-12	-3.9	-5.1	2.7e-07	0.75	0.81	0.16	FALSE
9	NTR	Blood	MAPKAP1	0.03	0.01	blup	441	0.02	2.3e-07	4.7	5.1	3.0e-07	0.05	0.42	0.57	TRUE
10	ROSMAP	Brain Pre-frontal Cortex	PPP6C	0.11	0.19	lasso	5	0.20	8.6e-26	-5.3	5.3	1.4e-07	-0.95	0.02	0.98	FALSE
11	ROSMAP	Brain Pre-frontal Cortex	SCAI	0.02	0.00	bslmm	316	0.00	3.3e-01	4.8	6.0	2.3e-09	-0.40	0.04	0.35	FALSE
12	The Cancer Genome Atlas	Breast Invasive Carcinoma	PPP6C	0.03	0.03	lasso	5	0.03	7.3e-07	-5.3	5.1	3.1e-07	-0.96	0.01	0.99	FALSE
13	The Cancer Genome Atlas	Breast Invasive Carcinoma	RABEPK	0.02	0.02	lasso	2	0.02	1.4e-04	-5.3	5.3	1.1e-07	-0.99	0.00	0.99	FALSE
14	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	PPP6C	0.05	0.06	lasso	3	0.05	1.1e-03	-5.3	5.3	9.4e-08	-0.98	0.01	0.90	FALSE
15	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	PPP6C	0.17	0.06	enet	5	0.09	2.0e-04	-5.3	5.3	1.1e-07	-0.99	0.01	0.79	FALSE