[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1), predicted percentage : ← →

chr20:24,485,525-26,307,797

Best TWAS P=1.6e-09 · Best GWAS P=4.36e-09 conditioned to 0.325

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ABHD12	0.10	0.17	blup	405	0.17	1.7e-20	-5.7	-5.2	1.6e-07	0.88	0.07	0.93	FALSE
2	GTEx	Adipose Subcutaneous	CTD-2514C3.1	0.06	0.02	enet	5	0.04	6.1e-04	-3.4	5.1	3.0e-07	-0.65	0.03	0.94	FALSE
3	GTEx	Artery Aorta	PYGB	0.07	0.02	lasso	9	0.02	3.4e-02	-4.7	-5.3	1.3e-07	0.72	0.10	0.56	FALSE
4	GTEx	Artery Aorta	ABHD12	0.06	0.03	enet	6	0.03	5.4e-03	-5.5	-5.5	3.3e-08	0.85	0.09	0.87	FALSE
5	GTEx	Artery Tibial	ABHD12	0.12	0.12	enet	25	0.15	7.1e-12	-5.6	-5.5	4.3e-08	0.89	0.10	0.90	FALSE
6	GTEx	Brain Caudate basal ganglia	ABHD12	0.09	0.05	enet	13	0.04	2.9e-02	-5.6	-5.8	8.1e-09	0.91	0.08	0.75	FALSE
7	GTEx	Brain Cerebellar Hemisphere	ENTPD6	0.22	0.26	lasso	3	0.17	3.8e-05	-5.5	5.4	5.6e-08	-0.96	0.10	0.89	FALSE
8	GTEx	Brain Cortex	ABHD12	0.08	0.11	lasso	8	0.09	1.4e-03	-5.6	-5.4	5.7e-08	0.88	0.07	0.74	FALSE
9	GTEx	Cells Transformed fibroblasts	ABHD12	0.24	0.33	lasso	4	0.35	6.3e-27	-5.6	-5.7	1.3e-08	0.91	0.09	0.91	FALSE
10	GTEx	Cells Transformed fibroblasts	GINS1	0.04	0.01	lasso	3	0.01	5.2e-02	-4.7	-5.7	9.3e-09	0.77	0.13	0.78	FALSE
11	GTEx	Colon Sigmoid	ABHD12	0.17	0.17	lasso	15	0.17	1.0e-06	-5.5	-5.7	1.4e-08	0.86	0.10	0.90	FALSE
12	GTEx	Esophagus Gastroesophageal Junction	ABHD12	0.15	0.14	lasso	13	0.14	7.0e-06	-5.5	-5.1	2.7e-07	0.94	0.09	0.91	FALSE
13	GTEx	Esophagus Muscularis	ABHD12	0.10	0.10	enet	42	0.09	4.5e-06	-5.7	-5.3	9.7e-08	0.83	0.08	0.92	FALSE
14	GTEx	Heart Atrial Appendage	ABHD12	0.07	0.06	enet	16	0.06	1.0e-03	-5.8	-5.8	8.9e-09	0.92	0.08	0.91	FALSE
15	GTEx	Heart Left Ventricle	ABHD12	0.15	0.14	lasso	10	0.12	4.0e-07	-5.6	-5.6	2.1e-08	0.91	0.08	0.92	FALSE
16	GTEx	Liver	ABHD12	0.20	0.20	lasso	19	0.15	7.3e-05	-5.7	-5.8	6.2e-09	0.93	0.07	0.92	FALSE
17	GTEx	Nerve Tibial	ABHD12	0.24	0.44	lasso	11	0.44	5.1e-34	-5.7	5.5	3.3e-08	-0.92	0.07	0.93	FALSE
18	GTEx	Ovary	ABHD12	0.23	0.04	lasso	8	0.05	1.9e-02	-5.7	-5.4	5.3e-08	0.86	0.07	0.69	FALSE
19	GTEx	Pituitary	ABHD12	0.27	0.31	enet	25	0.31	1.8e-08	-5.7	-5.3	1.3e-07	0.88	0.08	0.92	FALSE
20	GTEx	Spleen	PYGB	0.15	0.09	lasso	6	0.04	2.6e-02	-5.7	-6.0	1.6e-09	0.90	0.08	0.84	TRUE
21	GTEx	Testis	ABHD12	0.21	0.18	enet	25	0.23	1.1e-10	-5.6	-5.1	2.8e-07	0.87	0.08	0.92	FALSE
22	GTEx	Thyroid	ABHD12	0.05	0.04	lasso	5	0.03	3.9e-03	-5.7	5.8	7.6e-09	-0.95	0.07	0.91	FALSE
23	GTEx	Thyroid	NINL	0.13	0.18	enet	17	0.20	6.2e-15	4.5	5.9	4.7e-09	-0.80	0.40	0.60	FALSE
24	GTEx	Thyroid	VN1R108P	0.05	0.01	lasso	2	0.02	1.8e-02	-4.8	-5.9	3.2e-09	0.82	0.07	0.81	FALSE
25	GTEx	Whole Blood	PYGB	0.17	0.14	enet	22	0.18	2.7e-16	-5.7	-5.2	2.5e-07	0.88	0.08	0.92	FALSE
26	NTR	Blood	PYGB	0.07	0.10	enet	22	0.12	3.6e-36	-5.7	-5.3	1.2e-07	0.88	0.08	0.92	FALSE
27	YFS	Blood	ABHD12	0.15	0.35	bslmm	390	0.34	2.2e-118	-5.6	-5.7	1.5e-08	0.92	0.08	0.92	FALSE
28	YFS	Blood	PYGB	0.36	0.49	enet	50	0.56	7.4e-226	-4.5	-5.3	1.2e-07	0.87	0.30	0.70	FALSE
29	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	ABHD12	0.04	0.00	blup	77	0.02	6.6e-03	-5.7	-5.7	9.7e-09	0.88	0.04	0.55	FALSE
30	The Cancer Genome Atlas	Glioblastoma Multiforme	ABHD12	0.14	0.10	lasso	5	0.13	1.1e-04	-5.5	-5.7	9.6e-09	0.89	0.05	0.90	FALSE
31	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ABHD12	0.04	0.03	blup	77	0.04	4.0e-05	-5.6	-6.0	2.6e-09	0.91	0.06	0.94	FALSE
32	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	GINS1	0.03	0.01	enet	13	0.02	4.3e-03	-4.8	-5.6	2.0e-08	0.79	0.03	0.66	FALSE
33	The Cancer Genome Atlas	Brain Lower Grade Glioma	ABHD12	0.04	0.06	blup	77	0.06	2.2e-07	-5.6	-5.8	8.7e-09	0.93	0.05	0.95	FALSE
34	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	ABHD12	0.07	0.05	blup	77	0.05	2.4e-03	-5.7	-5.5	3.4e-08	0.92	0.05	0.85	FALSE
35	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	ABHD12	0.08	0.09	blup	80	0.09	1.7e-06	-5.6	-5.5	3.6e-08	0.91	0.05	0.95	FALSE
36	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	ENTPD6	0.07	0.07	lasso	1	0.04	9.2e-03	-5.5	5.5	4.7e-08	-0.96	0.01	0.91	FALSE
37	The Cancer Genome Atlas	Prostate Adenocarcinoma	ABHD12	0.03	0.02	lasso	4	0.03	5.8e-04	5.0	-5.3	9.3e-08	0.79	0.06	0.78	FALSE
38	The Cancer Genome Atlas	Testicular Germ Cell Tumors	NINL	0.11	0.03	blup	81	0.07	2.1e-03	5.0	5.5	3.5e-08	-0.90	0.03	0.72	FALSE
39	The Cancer Genome Atlas	Thyroid Carcinoma	ENTPD6	0.16	0.14	lasso	4	0.13	1.2e-12	-5.5	5.4	7.5e-08	-0.97	0.01	0.99	FALSE
40	The Cancer Genome Atlas	Thyroid Carcinoma	NINL	0.08	0.14	lasso	11	0.13	2.9e-12	-5.7	5.5	4.9e-08	-0.91	0.03	0.97	FALSE