TWAS hub - AP2A2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0900	0.0240	2.9e-08	0.041	0.064	0.066	0.064	0.064	9.3e-06	3.3e-08	1.9e-08	3.1e-08	3.2e-08
2	GTEx	Adipose Subcutaneous	0.0810	0.0350	4.2e-03	0.001	NA	0.007	NA	0.003	2.4e-01	NA	7.6e-02	NA	1.7e-01
3	GTEx	Uterus	0.7260	0.1510	6.6e-03	-0.009	NA	0.004	NA	-0.014	5.2e-01	NA	2.6e-01	NA	8.0e-01
4	ROSMAP	Brain Pre-frontal Cortex	0.2083	0.0411	1.9e-09	0.153	0.091	0.153	0.156	0.149	3.3e-19	9.2e-12	3.3e-19	1.7e-19	1.0e-18
5	YFS	Blood	0.0611	0.0179	6.2e-06	0.032	0.018	0.029	0.031	0.030	7.3e-11	1.1e-06	6.2e-10	1.5e-10	2.9e-10
6	TCGA	Breast Invasive Carcinoma	0.0502	0.0215	5.3e-06	0.015	0.032	0.023	NA	0.019	4.0e-04	3.0e-07	1.4e-05	NA	6.9e-05
7	TCGA	Kidney Renal Clear Cell Carcinoma	0.0595	0.0310	1.0e-04	0.013	0.040	0.043	NA	0.039	1.2e-02	2.6e-05	1.1e-05	NA	2.9e-05
8	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1620	0.0650	6.3e-05	0.098	0.107	0.089	NA	0.085	3.0e-06	1.1e-06	8.6e-06	NA	1.3e-05
9	TCGA	Brain Lower Grade Glioma	0.0756	0.0359	1.1e-03	0.024	0.047	0.037	NA	0.041	8.7e-04	4.0e-06	3.9e-05	NA	1.8e-05
10	TCGA	Soft Tissue Sarcoma	0.1150	0.0570	5.7e-03	0.003	0.027	0.010	NA	0.003	2.0e-01	9.5e-03	7.5e-02	NA	2.0e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Back pain experienced in last month	5.4	7.8	17.9	-2.8	-0.5	-0.2	-3.9	-4.2	-1.9	-3.4	-3.5	-3.1	-0.6
Mother’s age at death	5.2	6.5	12.1	3.0	1.6	0.5	2.6	2.7	2.3	3.5	2.8	2.6	2.7
Medication: Lansoprazole	4.9	5.5	8.8	-2.8	-2.8	-2.4	-1.8	-1.8	-2.2	-3.0	-2.5	-2.4	-1.4
Medication: Co-codamol	4.4	5.1	12.8	-3.6	-2.5	-0.1	-1.8	-1.8	-1.8	-3.4	-2.1	-1.8	-1.8
Medication: Allopurinol	3.7	4.9	8.1	-2.9	-2.1	-1.6	-2.1	-1.9	-2.2	-2.2	-2.4	-2.7	-1.9
Medication for cholesterol	3.4	5.1	14.6	3.8	2.2	0.9	1.4	1.5	1.5	3.5	2.4	1.9	1.4
Townsend deprivation index at recruitment	3.3	4.6	8.5	-2.6	-1.3	-0.3	-1.8	-1.9	-2.9	-2.7	-2.9	-2.5	-0.9
Alcohol usually taken with meals	3.3	5.3	13.6	2.1	0.6	2.5	0.5	0.3	3.7	2.7	2.4	2.3	3.0
Maternal smoking around birth	3.2	4.7	7.1	-1.5	-0.7	-1.1	-2.2	-2.4	-2.6	-2.4	-2.6	-2.7	-2.3
Average weekly red wine intake	3.1	4.5	14.1	1.0	-0.4	0.7	1.5	1.0	3.0	1.7	2.1	3.0	3.8
Relative age voice broke	2.9	4.4	8.2	2.3	-0.5	-0.6	2.5	2.6	1.9	2.9	2.2	1.7	2.4
Stomach or abdominal pain in last month	2.8	3.5	7.6	-1.2	0.9	-0.6	-2.3	-2.4	-1.7	-1.5	-1.7	-2.8	-2.2
Irritability	2.7	4.6	6.7	-2.6	-2.2	-0.8	-2.0	-2.3	-1.9	-2.5	-2.3	-2.1	-2.1
Ever had stillbirth, spontaneous miscarriage or termination	2.6	2.8	7.8	-1.1	-0.6	-0.5	-1.9	-1.8	-1.6	-2.2	-1.3	-1.4	-2.8
Relative age of first facial hair	2.5	5.1	10.1	3.2	-0.9	0.1	2.4	2.6	1.8	3.1	2.4	1.9	2.5
Noisy workplace	2.5	3.1	6.4	-2.5	-0.9	0.2	-1.4	-1.4	-1.8	-2.5	-2.1	-1.6	-1.7
Pulse wave peak to peak time	2.5	2.9	6.7	-1.7	-0.7	1.8	1.9	1.7	2.0	0.5	2.1	2.6	-0.2
Handedness (chirality/laterality): Left-handed	2.5	3.0	5.7	1.7	1.3	-0.8	1.2	1.2	2.1	2.3	2.3	2.4	1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.4	2.8	8.5	-0.4	-0.7	-2.9	2.1	2.0	0.6	1.0	0.6	1.1	2.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.4	2.8	8.7	0.1	-0.9	-3.0	-1.6	-1.7	-2.0	-1.1	-1.7	-2.0	-0.2
Diabetes (self-reported)	2.2	3.3	7.8	-0.2	-0.8	-2.1	-2.8	-2.8	-1.2	-1.3	-1.7	-2.5	-0.7
Average weekly spirits intake	2.1	2.5	4.5	-1.6	-1.6	-2.1	-0.9	-1.3	-2.1	-1.5	-2.1	-1.6	0.2
Illnesses of mother	2.1	2.6	7.3	2.7	0.7	2.3	0.5	0.6	1.4	1.9	1.0	1.1	2.1
Number of full sisters	2.1	2.5	5.3	-1.7	-0.6	-0.5	-1.1	-1.2	-2.3	-2.2	-2.2	-1.7	-1.0
Bipolar Disorder or Schizophrenia	2.0	5.0	7.9	2.1	1.0	-0.7	2.8	2.8	1.9	2.1	2.5	2.8	2.7
Body mass index (BMI)	2.0	8.4	29.7	-5.5	-3.0	-0.8	-0.9	-0.5	-2.6	-4.5	-3.1	-2.2	-1.6
Financial difficulties in last 2 years	2.0	2.6	8.6	-1.4	-1.4	-2.9	-0.2	0.0	-2.6	-1.4	-2.0	-1.2	-0.2
Osteoporosis (self-reported)	2.0	2.5	5.3	2.3	0.7	-0.3	1.6	1.7	1.3	2.1	1.9	1.8	0.8
Medication: Blood pressure	2.0	3.9	14.2	-3.8	-2.2	-0.7	-1.2	-1.4	-0.4	-3.4	-1.8	-0.4	0.6
Coronary Artery Disease (CAD)	1.9	2.3	9.2	0.0	0.0	0.0	0.0	0.0	-2.3	-1.5	-1.8	-1.7	-3.0
Systolic Blood Pressure	1.9	9.5	25.0	-5.0	-3.1	-1.0	-2.3	-2.6	-2.8	-4.5	-3.5	-2.1	-1.5
Other serious medical condition/disability diagnosed by doctor	1.9	2.5	4.6	1.1	0.8	0.4	2.0	2.0	1.7	1.7	2.0	2.1	0.5
Medication for hormone replacement therapy	1.9	2.2	5.0	-1.8	-1.4	-1.0	-0.7	-0.9	-1.2	-2.2	-1.3	-1.7	-1.8
Lung cancer (father)	1.9	2.2	4.5	-0.1	-0.7	1.8	-1.8	-2.1	-0.9	-1.7	-1.8	-1.8	1.0
Gout (self-reported)	1.9	2.5	5.3	-2.3	-1.1	-1.2	-1.5	-1.5	-1.7	-1.1	-1.6	-2.1	-1.5
Medication: Lisinopril	1.9	2.4	14.2	-3.8	-0.9	0.5	-0.2	-0.3	0.3	-2.3	-0.4	0.3	-1.8
Alcohol drinker status: Previous	1.9	2.2	3.5	-1.7	0.2	-0.5	-1.5	-1.6	-1.7	-1.9	-1.7	-1.7	-1.0
Alzheimer’s Disease (including proxy)	1.8	2.7	11.1	-1.6	-3.3	0.3	0.0	-0.0	-1.9	-1.7	-2.2	-1.2	0.3
Impedance of arm (right)	1.8	8.2	24.2	3.8	2.2	-0.2	1.4	0.9	3.2	4.9	3.5	2.8	2.2
Serious illness, injury or assault of a close relative in last 2 years	1.8	2.1	7.1	-1.8	0.5	-0.5	-0.3	-0.1	-2.7	-1.2	-1.9	-1.3	-1.8
Pulse wave Arterial Stiffness index	1.8	2.1	4.8	2.2	0.7	-1.5	-1.6	-1.4	-1.5	0.1	-1.5	-2.1	0.7
Length of working week for main job	1.8	2.0	9.0	-1.4	0.2	0.7	-1.5	-1.2	-1.3	-0.8	-0.7	-1.4	-3.0
Birth weight	1.8	3.9	6.5	2.2	2.1	1.2	1.6	1.9	1.8	2.5	2.1	1.9	1.9
Chronic bronchitis/emphysema (mother)	1.8	2.1	4.4	-1.3	1.0	-1.9	-1.2	-1.1	-1.3	-1.6	-1.1	-1.3	-2.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.8	2.1	3.8	-2.0	-1.0	-0.6	-1.8	-1.6	-1.2	-1.6	-1.9	-1.6	-0.0
Impedance of whole body	1.8	9.0	29.9	5.5	2.2	0.5	0.7	0.2	3.0	4.8	3.2	2.1	2.7
Impedance of leg (left)	1.7	8.0	37.5	6.1	2.0	0.5	0.4	0.1	2.7	3.7	2.8	1.6	2.7
Exposure to tobacco smoke at home	1.7	2.0	5.5	-0.1	-0.7	-1.1	2.2	2.4	0.9	1.4	1.5	1.6	0.3
Loud music exposure frequency	1.7	1.8	6.4	-2.1	-2.5	0.4	-0.6	-0.7	-0.6	-2.0	-1.2	-0.6	-0.2
Mouth/teeth dental problems: Bleeding gums	1.7	2.2	3.8	2.0	1.5	-0.4	1.0	1.4	0.9	1.9	1.2	1.8	1.9
Eye problems/disorders: None of the above	1.7	1.9	7.2	-2.7	-1.1	-1.7	1.5	1.1	-1.2	-0.8	-0.7	-0.2	-1.4
Ever had bowel cancer screening	1.7	2.0	4.0	1.3	1.3	-1.5	0.7	0.6	1.8	1.5	1.4	1.2	2.0
Bipolar Disorder (2018)	1.6	2.6	4.5	1.6	0.5	-0.7	2.1	2.1	0.8	2.0	1.8	1.9	1.5
BMI	1.6	9.5	40.3	-6.3	-2.9	-1.4	0.1	0.7	-2.5	-4.2	-2.4	-1.8	-3.2
Impedance of leg (right)	1.6	7.9	34.8	5.9	2.3	-0.2	0.4	0.1	2.5	3.9	2.8	1.8	2.4
Impedance of arm (left)	1.6	7.3	23.0	4.1	2.4	0.1	1.0	0.4	2.7	4.8	3.1	2.3	2.1
Worry too long after embarrassment	1.6	2.7	7.1	0.6	0.6	-1.9	-1.9	-1.6	-1.8	-0.9	-1.5	-2.7	-1.8
Fasting Glucose	1.5	1.7	3.4	-0.8	-1.0	-1.9	1.6	1.8	1.5	-0.1	1.3	1.6	0.2
Medication: Amlodipine	1.5	2.1	4.4	0.2	-1.1	0.0	-2.0	-2.1	-1.6	-1.5	-2.0	-1.7	0.0
Overall health rating	1.5	3.2	7.4	-2.1	-0.6	-0.8	-2.7	-2.6	-0.6	-2.0	-1.1	-1.7	-2.1
Alcohol drinker status: Never	1.5	1.8	7.3	1.7	2.7	1.4	0.1	0.0	0.0	2.0	0.9	0.3	-0.8
Average weekly beer plus cider intake	1.5	2.2	6.2	-1.5	-0.3	1.6	-0.3	-0.4	-1.8	-1.6	-1.7	-1.4	-2.5
Age at First Birth	1.4	2.0	5.7	1.5	2.4	-1.9	0.7	1.4	-0.9	1.3	0.5	-0.4	-1.8
Qualifications: CSEs or equivalent	1.4	1.9	5.1	-1.3	0.2	1.5	-0.1	-0.1	-2.3	-1.8	-1.8	-1.3	-1.4
Number of live births	1.4	2.0	4.9	-1.5	-0.4	1.0	-1.3	-1.8	-1.2	-2.2	-1.8	-1.1	-1.2
Peak expiratory flow (PEF)	1.4	3.4	7.5	1.8	1.8	-0.7	2.2	2.7	1.1	1.9	1.7	2.1	1.3
Friendships satisfaction	1.4	1.7	4.2	0.1	-0.2	-0.8	1.4	1.9	1.4	1.2	1.7	2.0	0.7
Arm fat mass (left)	1.4	5.6	21.6	-4.7	-2.8	-0.2	-0.7	-0.5	-1.8	-3.6	-2.6	-1.8	-0.7
Ever depressed for a whole week	1.4	1.8	4.9	1.5	-1.5	-0.9	1.5	1.8	-0.8	0.9	0.1	0.7	2.2
Heart disease (siblings)	1.4	1.8	8.7	-0.1	-0.7	2.9	-0.4	-0.3	1.0	0.3	0.0	0.4	2.7
Schizophrenia (2018)	1.3	2.7	5.0	1.4	0.9	-0.5	1.9	1.8	1.7	1.2	1.7	2.0	2.2
Irritable Bowel Disease (IBD)	1.3	3.1	7.9	-0.5	0.4	-1.2	2.3	2.4	2.8	0.8	2.4	2.1	0.7
Systolic blood pressure, automated reading	1.3	3.7	11.2	-3.3	-2.7	-1.5	-0.8	-0.8	-1.5	-2.8	-1.8	-0.6	-0.8
Ever had prostate specific antigen (PSA) test	1.3	1.5	2.9	0.3	0.4	0.1	1.7	1.4	1.2	1.6	1.6	1.6	0.8
Breast Cancer	1.2	2.9	8.8	1.4	-3.0	1.1	-1.4	-2.1	0.4	-0.2	-1.1	-1.0	2.8
Waist circumference	1.2	4.3	13.6	-3.7	-2.9	-0.8	-0.8	-0.8	-1.4	-3.2	-2.1	-1.5	-0.1
Arm fat mass (right)	1.2	5.0	21.5	-4.6	-2.8	-0.4	-0.3	-0.1	-1.4	-3.4	-2.2	-1.3	-0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	1.2	1.8	4.5	2.1	1.4	-1.4	1.3	1.6	0.6	1.1	1.2	0.8	1.3
Pulse wave reflection index	1.2	1.5	3.9	2.0	1.3	-1.4	-1.1	-0.8	-0.9	0.6	-0.9	-1.8	0.1
Heart disease (mother)	1.2	1.5	3.0	-0.6	-0.3	-1.3	-1.7	-1.6	-1.1	-0.8	-1.3	-1.7	-0.8
Eye problems/disorders: Cataract	1.2	1.4	4.6	2.1	1.1	1.8	-0.3	-0.1	0.9	1.2	1.2	0.9	0.6
Risk taking	1.2	1.8	3.9	-1.6	0.5	2.0	-0.9	-0.8	-1.2	-1.6	-1.0	-1.0	-1.9
Leg fat mass (left)	1.2	4.7	14.3	-3.8	-2.9	-0.2	-1.1	-0.9	-1.4	-3.4	-2.4	-1.7	0.2
Body Mass Index (BMI) (2010)	1.1	1.5	6.9	-2.6	-1.7	0.8	-0.7	-0.5	-0.3	-1.4	-0.9	-0.5	-1.1
High blood pressure	1.1	3.2	8.5	-2.8	-2.0	-0.8	-1.5	-1.5	-0.8	-2.9	-2.0	-1.3	0.4
Birth weight of first child	1.1	2.0	3.2	0.8	-0.5	0.8	1.8	1.8	1.6	1.5	1.5	1.8	1.4
Number of full brothers	1.1	1.4	3.2	-1.4	-0.7	1.3	-0.4	-0.6	-1.8	-1.4	-1.6	-1.1	0.3
Medication: Seretide 50 evohaler	1.1	1.3	4.3	2.0	1.2	2.1	-0.9	-0.6	0.4	0.9	0.8	-0.6	-0.2
Leg fat mass (right)	1.1	4.4	14.1	-3.8	-2.8	-0.4	-1.0	-0.8	-1.4	-3.2	-2.3	-1.5	0.2
Arm fat percentage (left)	1.1	4.3	18.1	-4.3	-2.5	-0.7	-0.4	-0.3	-1.4	-3.0	-2.0	-1.4	-0.5
Osteoarthritis (self-reported)	1.1	1.5	4.2	-0.3	1.1	-1.0	2.0	2.0	0.4	0.4	1.0	1.5	0.7
Guilty feelings	1.1	1.6	4.3	-1.0	-1.8	-0.8	-0.8	-0.8	-2.1	-1.0	-1.8	-1.2	-0.0
Wears glasses or contact lenses	1.1	1.3	4.8	1.9	0.8	-0.8	-0.5	-0.4	1.0	2.2	1.4	0.4	-0.1
Ever taken oral contraceptive pill	1.1	1.2	4.4	0.3	1.1	-0.6	1.4	2.1	-0.5	0.6	0.7	0.6	-1.5
Vascular/heart problems diagnosed by doctor	1.1	3.0	7.8	2.8	1.9	1.0	1.6	1.7	0.3	2.7	1.8	1.2	-0.7
Ulcerative Colitis (UC)	1.0	1.9	5.4	-0.3	0.9	-1.0	1.7	1.7	2.3	0.9	1.8	1.3	0.4
Prostate Cancer	1.0	1.4	5.9	0.0	0.7	2.4	-1.4	-1.3	0.6	-0.3	0.2	-0.6	-1.8
Crohns Disease (2012)	1.0	1.6	2.8	-0.4	-0.8	-1.6	1.4	1.2	1.7	0.6	1.5	1.6	1.3
Lupus	1.0	1.5	4.2	0.4	-1.9	1.2	-1.4	-1.4	0.1	-0.6	-1.2	-0.4	2.1
Rheumatoid Arthritis	1.0	1.3	3.0	0.4	0.6	-0.3	1.7	1.7	0.8	1.3	0.9	1.5	1.2
Schizophrenia (2014)	1.0	2.2	4.1	2.0	1.3	0.1	1.3	1.3	1.2	1.7	1.5	1.5	1.9
Cardiovascular Disease	1.0	3.3	10.9	-3.3	-2.4	-0.5	-0.9	-0.8	-1.1	-2.4	-1.6	-1.6	-1.6
Respiratory disease	1.0	2.2	9.3	-0.6	0.9	-3.1	-0.8	-0.6	-2.0	-0.7	-1.5	-1.7	-0.6
Past tobacco smoking	1.0	1.8	4.5	1.2	1.6	1.8	0.8	0.6	0.9	2.1	1.6	1.2	-0.6
Hearing difficulty/problems with background noise	1.0	1.6	8.1	-2.9	-0.8	0.4	-0.9	-0.9	-0.3	-1.8	-0.6	0.0	-1.4
Medication: Simvastatin	1.0	1.5	5.5	-1.3	-2.0	-2.4	-0.0	0.1	-0.9	-1.1	-1.0	-0.6	0.5
Hip circumference	1.0	4.5	19.2	-4.4	-2.4	-0.4	-0.2	-0.1	-1.6	-3.2	-2.2	-1.3	-0.3
Ever highly irritable/argumentative for 2 days	1.0	1.2	3.0	-1.4	-0.4	-1.7	-0.4	0.1	-1.3	-0.9	-1.1	-1.2	-1.2
Health satisfaction	1.0	1.2	4.3	-1.0	-0.3	-2.1	-1.1	-0.6	-0.4	-0.8	-0.7	-1.5	-1.3
Smoking status: Previous	1.0	1.6	5.2	-1.2	-1.0	-2.3	-0.5	-0.1	-1.0	-1.9	-1.4	-1.1	0.1
Mineral and other dietary supplements	1.0	1.3	3.5	1.1	0.6	0.8	-1.4	-1.2	-1.1	-1.1	-1.3	-1.9	-0.4
High cholesterol (Self-reported)	1.0	1.7	6.1	-1.2	-2.5	-0.9	0.2	0.6	-1.3	-1.6	-1.3	-1.4	-0.2
Commuting to job workplace: Cycle	1.0	1.2	4.8	1.3	1.0	2.2	-0.6	-0.6	-0.6	1.0	-0.7	-0.7	1.4
Depression (Nagel 2018)	0.9	1.3	2.6	1.5	1.1	0.4	1.3	1.3	0.2	1.6	1.3	1.2	-0.9
Frequency of depressed mood in last 2 weeks	0.9	1.3	2.9	0.8	1.5	-0.1	1.1	1.1	0.3	1.2	1.3	1.1	-1.7
High blood pressure (mother)	0.9	1.3	6.7	-2.6	-0.5	-1.2	0.6	0.6	-0.7	-1.3	-0.4	-0.1	-1.2
Number of incorrect matches in round	0.9	1.6	3.1	0.7	-1.0	1.0	1.4	1.0	1.5	1.1	1.4	1.8	1.3
Pain all over the body in last month	0.9	0.9	2.5	-0.2	-0.2	0.4	1.3	0.8	1.4	0.5	0.7	1.2	1.6
Arm fat percentage (right)	0.9	3.7	17.6	-4.2	-2.4	-0.9	-0.1	-0.0	-1.1	-2.7	-1.7	-1.0	-0.3
Alcohol intake versus 10 years previously	0.9	1.3	4.4	-1.5	-0.2	-2.1	-0.1	0.1	-1.5	-1.2	-0.9	-0.2	-1.4
Pulse rate	0.9	1.5	6.3	-1.7	-1.1	0.4	-0.5	-0.7	-0.9	-2.5	-1.6	-0.2	0.5
Medication: Cholesterol lowering	0.9	1.3	3.7	-0.9	-1.9	-1.7	-0.3	-0.3	-0.8	-1.0	-1.3	-1.2	1.0
Prospective memory result	0.9	1.1	3.5	-1.9	-0.7	1.0	-0.5	-0.6	-0.9	-1.9	-1.2	-0.2	0.5
Breastfed as a baby	0.9	1.2	2.7	1.5	1.0	1.3	-0.3	-0.6	1.2	0.5	0.6	1.2	1.6
Number of children fathered	0.9	1.1	4.6	-2.1	-1.7	0.1	-0.0	-0.2	-0.3	-1.3	-1.0	0.0	-0.0
Mouth/teeth dental problems: Loose teeth	0.9	1.1	2.8	-1.3	1.5	-1.7	-0.2	-0.2	-1.3	-0.1	-0.6	-0.6	-1.3
Neck or shoulder pain in last month	0.9	1.3	2.5	-0.9	-1.1	-1.1	-1.3	-1.6	-1.2	-1.0	-1.2	-1.1	0.4
Whole body fat mass	0.9	3.7	14.1	-3.8	-2.9	-0.3	-0.5	-0.4	-1.1	-2.7	-2.0	-1.2	0.3
Chest pain or discomfort	0.9	1.3	3.8	0.5	-0.6	-1.2	-0.9	-0.7	-1.9	-0.3	-1.6	-1.6	0.5
Family relationship satisfaction	0.9	1.0	2.1	0.6	0.4	-0.7	1.2	1.4	1.1	1.3	1.2	1.0	0.7
Qualifications: NVQ or HND or HNC or equivalent	0.9	1.1	3.2	-1.8	-1.8	-0.6	0.4	0.5	-0.9	-0.9	-0.4	-0.0	-1.5
Medication: Aspirin	0.9	1.1	3.0	-0.7	-1.4	1.7	1.2	0.9	1.1	0.4	0.8	1.1	0.8
Hearing aid user	0.9	1.0	2.4	-0.2	1.3	-0.0	1.5	1.5	0.8	0.3	1.2	1.2	-0.5
Medication: Bendroflumethiazide	0.9	1.3	4.1	-2.0	-1.2	0.1	-1.1	-1.3	-0.2	-2.0	-0.9	-0.5	-0.2
Leg fat percentage (left)	0.9	3.3	8.5	-2.8	-2.5	-1.2	-1.0	-0.8	-1.1	-2.9	-1.9	-1.6	0.2
Crohns Disease (2017)	0.8	1.7	3.2	-0.8	0.1	-0.8	1.8	1.8	1.8	0.1	1.6	1.8	0.4
Verbal and Numeric Reasoning (VNR)	0.8	1.9	9.4	3.1	0.5	-1.6	-0.8	-0.7	0.8	1.8	0.8	-0.5	0.9
Ever used hormone-replacement therapy (HRT)	0.8	1.0	3.5	0.5	-0.2	-1.9	-1.3	-1.3	0.1	-0.4	-0.6	-1.3	0.8
Leg fat-free mass (left)	0.8	4.2	20.9	-4.6	-2.2	1.4	-0.4	-0.4	-1.3	-2.8	-2.1	-0.8	-0.3
Leg predicted mass (left)	0.8	4.4	21.2	-4.6	-2.2	1.5	-0.5	-0.4	-1.4	-2.8	-2.1	-0.8	-0.4
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.2	5.5	-0.1	0.5	-2.4	0.4	0.6	-1.1	0.5	0.3	-0.5	-2.0
Hair/balding pattern: Pattern 2	0.8	1.1	2.0	0.9	-0.3	1.2	1.3	1.4	1.4	-0.1	1.1	1.1	0.5
Weight	0.8	4.0	16.8	-4.1	-2.8	0.6	-0.3	-0.1	-1.1	-3.0	-1.9	-0.9	0.1
Hair/balding pattern: Pattern 3	0.8	1.2	3.0	0.4	1.5	0.7	-1.0	-0.8	-1.6	0.4	-1.1	-1.7	-1.1
Depression (self-reported)	0.8	1.0	3.7	1.8	1.9	-0.4	0.3	0.5	0.5	1.0	0.7	0.3	0.7
Blood clot in the leg (DVT)	0.8	1.0	1.9	0.3	1.4	1.3	1.1	1.4	0.9	0.7	1.3	0.9	-0.1
Leg fat percentage (right)	0.8	2.9	7.6	-2.8	-2.3	-1.5	-0.8	-0.7	-1.0	-2.7	-1.7	-1.3	0.2
Arm fat-free mass (right)	0.8	4.3	11.4	-3.4	-2.2	1.7	-1.0	-0.9	-1.6	-3.3	-2.4	-1.5	-0.1
Exposure to tobacco smoke outside home	0.8	1.0	4.5	-2.1	-1.4	-0.0	0.8	0.7	-0.7	-0.8	-0.6	0.2	-0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.8	1.1	3.6	1.2	1.9	-1.4	-0.9	-0.5	-0.8	0.3	0.1	-0.9	-0.9
Suffer from ‘nerves’	0.8	1.3	2.9	0.3	-0.8	-0.5	-1.7	-1.6	-0.8	-1.2	-0.9	-1.6	-0.9
Leg fat-free mass (right)	0.8	4.3	19.1	-4.4	-2.2	1.8	-0.4	-0.3	-1.4	-2.8	-2.1	-0.9	-0.4
Leg predicted mass (right)	0.8	4.2	18.5	-4.3	-2.2	1.9	-0.4	-0.3	-1.3	-2.7	-2.1	-0.9	-0.4
Tinnitus: Yes, now most or all of the time	0.8	0.9	2.5	-0.6	-0.7	-0.6	-0.9	-1.3	1.1	-0.9	-0.4	-0.3	1.6
Supplements: Fish oil (including cod liver oil)	0.8	1.1	2.3	-1.5	-0.7	-1.5	1.1	1.1	0.8	0.4	1.0	1.4	0.1
Medication: Atorvastatin	0.8	1.0	3.3	-0.3	-1.3	0.6	-0.8	-1.0	-0.6	-0.8	-1.0	-1.8	-0.6
Arm fat-free mass (left)	0.8	4.1	13.0	-3.6	-2.6	1.3	-0.7	-0.5	-1.2	-3.3	-2.2	-1.1	0.2
Age started oral contraceptive pill	0.8	1.0	4.3	-0.6	0.3	-2.1	1.2	1.3	0.4	0.3	0.6	1.1	0.5
Unable to work because of sickness or disability	0.8	1.0	5.1	-1.0	-0.4	-2.2	0.6	1.2	0.5	-0.1	0.8	0.4	-1.0
Cholesterol lowering medication	0.8	1.1	3.1	-1.6	-1.8	-1.2	-0.1	0.0	-0.5	-1.1	-0.7	-0.9	-1.1
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	1.8	0.4	1.4	1.1	1.1	1.3	0.9	0.7	1.4	1.0	-0.1
Alzheimer’s Disease (in father)	0.7	0.8	2.3	0.6	-0.9	-1.5	1.0	0.8	-0.3	0.3	-0.1	0.2	1.5
Mean Putamen Volume	0.7	0.8	3.6	-1.9	0.1	0.9	0.9	0.5	-0.1	-1.2	-0.2	0.9	-0.4
HbA1C	0.7	0.8	4.4	0.3	-2.1	-0.7	0.9	0.9	-0.0	0.9	0.1	0.3	0.8
Type 2 Diabetes (T2D) (2018)	0.7	1.3	3.7	-0.3	-0.0	-0.8	-1.9	-1.9	-0.4	-1.0	-0.8	-1.5	-1.0
Supplements: Glucosamine	0.7	1.0	3.0	0.7	1.7	-1.0	1.0	1.1	-0.1	1.3	0.9	0.6	-0.1
Ever unenthusiastic/disinterested for a whole week	0.7	0.8	3.4	-0.0	-1.2	-0.6	0.8	1.1	-0.6	0.5	-0.4	0.4	1.8
Happiness	0.7	0.9	2.2	-0.8	-1.5	-0.2	1.2	1.2	0.5	-0.1	0.1	0.7	1.4
Headache pain in last month	0.7	1.1	4.7	0.9	1.9	2.2	0.4	-0.0	0.6	0.7	0.7	0.8	-0.1
Age at first live birth	0.7	1.2	4.5	2.1	0.5	-1.1	0.2	0.4	0.9	1.5	1.4	0.8	-0.7
Arm predicted mass (right)	0.7	3.5	9.5	-3.1	-2.2	1.7	-0.8	-0.6	-1.3	-3.0	-2.1	-1.2	0.1
Hypertension (Self-reported)	0.7	2.0	5.4	-2.3	-1.8	-0.7	-1.1	-1.1	-0.6	-2.3	-1.4	-1.0	0.1
Diabetes diagnosed by doctor	0.7	1.1	3.0	0.0	-1.0	-1.0	-1.6	-1.7	-0.4	-0.8	-0.8	-1.4	0.1
Ever smoked	0.7	1.2	2.4	-0.5	-1.4	-1.6	-0.4	-0.3	-0.9	-1.5	-1.3	-1.2	0.9
Basal metabolic rate	0.7	3.9	15.5	-3.9	-2.2	1.6	-0.4	-0.4	-1.3	-3.0	-2.1	-0.9	-0.0
Fractured/broken bones in last 5 years	0.7	0.9	1.8	1.0	1.1	-0.4	0.7	0.9	0.9	1.1	1.3	1.3	0.0
Diastolic blood pressure, automated reading	0.7	2.3	6.5	-1.7	-1.4	1.3	-1.1	-0.7	-1.2	-2.5	-1.7	-1.2	-1.5
Basal cell carcinoma (self-reported)	0.7	0.8	2.3	-0.4	-1.5	1.1	-1.0	-1.3	-0.1	-0.6	-0.6	-0.3	0.8
Arm predicted mass (left)	0.7	3.5	12.3	-3.5	-2.3	1.5	-0.5	-0.3	-1.1	-3.0	-2.0	-0.9	0.2
Intelligence (Savage-Jansen 2018)	0.6	1.9	7.8	2.8	0.8	-1.6	-1.0	-1.2	0.2	1.5	0.1	-1.0	1.4
Alzheimer’s Disease (in mother)	0.6	0.6	3.0	0.4	-1.3	1.7	0.1	0.1	-0.2	0.2	-0.6	-0.2	1.1
Waist Hip Ratio (WHR)	0.6	2.7	7.1	2.4	-1.5	1.1	0.5	0.1	1.6	1.8	1.4	1.3	2.7
Lung FEV1/FVC ratio	0.6	2.9	13.8	-3.7	-1.8	-0.2	1.6	1.8	-0.7	-2.1	-1.0	-0.0	0.5
Neuroticism	0.6	1.4	6.7	-0.3	0.7	-1.3	0.1	0.3	-1.6	0.1	-0.6	-1.5	-2.6
Hand grip strength (right)	0.6	1.5	5.9	1.7	0.0	2.2	0.1	0.1	0.7	0.6	0.1	0.9	2.4
Taking other prescription medications	0.6	1.0	2.4	-0.3	-0.1	-1.5	1.1	1.2	1.4	0.1	1.3	0.8	-0.5
Serious illness, injury or assault to yourself	0.6	0.7	2.9	1.1	1.7	-0.4	-0.0	0.4	0.5	0.7	0.7	0.6	-1.0
Chronic bronchitis/emphysema (father)	0.6	0.8	2.7	0.6	-0.1	1.6	-0.3	-0.4	1.2	0.7	0.7	0.9	1.0
Trunk fat mass	0.6	2.8	11.1	-3.3	-2.8	-0.1	-0.3	-0.3	-0.7	-2.2	-1.5	-0.9	0.6
Had other major operations	0.6	0.8	4.0	0.2	-1.6	-2.0	0.3	0.5	-0.4	0.7	-0.1	-0.2	0.4
Mouth/teeth dental problems	0.6	1.0	2.7	-0.5	-0.9	1.6	-1.0	-1.5	-0.4	-0.8	-0.8	-1.0	-0.5
Medication: Ramipril	0.6	0.7	2.4	-1.2	-1.6	-1.0	-0.4	-0.1	-0.4	-1.0	-0.9	-0.5	-0.3
Fluid intelligence score	0.6	1.2	5.1	2.3	0.7	-1.9	-0.8	-0.7	0.6	1.1	0.5	-0.4	0.1
Time employed in main current job	0.6	0.6	3.1	0.4	0.5	1.8	-0.9	-1.3	0.4	-0.0	-0.0	-0.3	-0.5
Medication: Ventolin 100micrograms inhaler	0.6	0.7	2.4	-0.0	-0.1	-0.2	1.5	1.5	-0.2	0.9	0.5	1.0	0.5
Body fat percentage	0.6	2.5	9.1	-3.0	-2.6	-0.8	-0.4	-0.4	-0.8	-2.1	-1.5	-1.1	0.5
Comparative body size at age 10	0.6	1.8	8.3	-2.9	-1.3	1.8	1.1	1.0	-0.1	-1.2	-0.3	0.9	-0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	1.9	-0.7	-1.4	1.2	-0.6	-0.7	0.4	-0.7	-0.2	0.4	0.9
Shortness of breath walking on level ground	0.6	0.8	1.7	-0.1	1.1	-1.3	-1.2	-0.9	0.7	0.1	0.2	-0.4	-1.3
Migraine (self-reported)	0.6	0.8	2.4	-1.4	-1.5	0.5	0.4	-0.3	-0.5	-1.2	-0.7	0.7	0.4
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	6.1	0.1	-0.3	2.5	-0.4	-0.7	0.5	-0.1	0.1	0.3	0.1
Supplements: Vitamin C	0.6	0.7	2.5	-1.6	-0.6	0.4	1.2	0.9	-0.4	-0.2	0.0	0.6	-0.8
Knee pain experienced in last month	0.6	0.9	2.0	-1.1	-0.4	-1.4	1.0	1.1	-1.0	-0.6	-0.7	0.4	1.2
Mood swings	0.6	1.0	5.4	-1.1	0.8	-0.0	0.6	0.6	-0.7	-0.7	-0.5	-0.8	-2.3
Whole body water mass	0.6	3.5	13.5	-3.7	-2.0	1.7	-0.5	-0.4	-1.2	-2.8	-2.0	-0.7	-0.0
Financial situation satisfaction	0.6	0.7	2.0	-1.2	-1.4	-0.9	-0.1	-0.1	-1.4	-0.6	-0.9	-0.5	-0.3
Medication: Paracetamol	0.6	0.9	4.6	0.3	2.1	-1.4	0.5	0.4	0.2	0.7	0.8	-0.2	-0.8
LDL Cholesterol	0.5	0.8	2.7	-0.1	-0.8	-1.0	-0.9	-1.0	-0.9	-0.3	-0.8	-1.6	-0.3
Height	0.5	9.9	25.1	3.5	-1.0	3.3	0.7	-0.3	4.3	4.1	2.9	2.6	5.0
Smoking Status	0.5	1.1	3.0	-0.6	-0.9	-0.9	-0.9	-0.8	-0.5	-1.7	-1.4	-1.4	0.8
Hearing difficulty/problems: Yes	0.5	0.8	3.8	-1.6	-0.1	-0.4	-0.0	0.4	0.4	-0.9	0.7	0.6	-2.0
Eye problems/disorders: Diabetes related eye disease	0.5	0.5	1.1	0.7	0.1	-1.1	-0.7	-0.8	1.0	0.4	0.7	0.3	0.9
Diabetes (father)	0.5	0.7	2.0	0.9	1.4	-0.4	-1.2	-0.8	0.0	0.6	0.1	-0.8	-0.9
Current tobacco smoking	0.5	0.8	2.0	-0.4	-0.2	-0.3	-1.2	-1.4	-0.6	-0.8	-1.0	-1.2	0.6
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	2.2	0.6	0.9	0.1	0.2	0.3	0.3	1.5	0.8	0.5	-0.6
Medication: Atenolol	0.5	0.6	1.9	-1.4	-0.9	0.3	-0.5	-0.5	1.3	0.7	0.5	0.3	0.3
Nervous feelings	0.5	0.8	2.2	-0.4	-0.2	-0.9	-0.7	-0.5	-1.5	-0.7	-1.0	-1.0	-1.5
Had menopause	0.5	0.7	1.8	-0.3	-0.3	-1.3	-0.9	-0.9	0.4	-1.0	-0.5	-0.2	1.3
Worrier / anxious feelings	0.5	1.0	2.5	1.1	1.4	-1.6	0.0	0.3	0.1	1.3	0.8	-0.2	-1.1
Falls in the last year	0.5	0.7	2.2	0.7	-0.6	-1.1	0.5	0.8	-0.1	1.5	0.2	0.5	1.2
Mouth/teeth dental problems: Dentures	0.5	0.8	2.5	-0.7	1.1	-0.7	0.7	1.0	1.6	0.0	0.9	0.9	0.3
Asthma	0.5	1.0	4.3	-1.3	-0.3	-2.1	0.1	0.2	-1.0	-1.4	-0.8	-0.1	-0.2
Standing height	0.5	5.0	13.0	2.3	0.1	3.0	1.0	0.5	2.5	2.8	1.8	2.2	3.6
High blood pressure (siblings)	0.5	0.7	2.5	-1.6	-0.9	-0.9	-0.4	-0.5	-0.6	-1.2	-0.8	-0.0	-0.1
Qualifications: College or University degree	0.5	1.5	5.0	2.2	1.4	0.3	-0.0	0.1	0.4	2.1	1.2	-0.3	-1.5
Medication for pain relief, constipation, heartburn	0.5	0.9	3.0	0.7	0.2	0.1	-1.7	-1.4	-0.8	-0.7	-1.1	-0.8	0.0
Angina (self-reported)	0.5	0.7	1.8	0.4	-0.1	-0.5	-1.4	-1.2	-0.3	0.1	-0.6	-1.0	1.2
Comparative height size at age 10	0.5	2.9	4.6	1.5	0.8	1.4	1.2	0.9	2.1	2.1	2.0	2.1	2.1
Age at last live birth	0.5	0.7	3.0	1.7	0.5	-0.7	-0.2	-0.0	-0.1	0.9	0.8	0.6	-1.2
Whole body fat-free mass	0.5	3.1	12.2	-3.5	-1.9	1.8	-0.3	-0.3	-1.0	-2.6	-1.9	-0.6	0.2
Breast cancer (self-reported)	0.5	0.6	1.9	-0.3	0.8	-1.3	-0.7	-0.4	0.5	-0.5	0.1	-0.5	-1.4
Medication: Aspirin	0.5	0.7	1.2	-0.4	-1.0	1.1	0.9	0.6	1.1	0.5	0.7	0.9	0.9
Miserableness	0.5	0.9	2.4	1.1	0.5	-0.6	1.2	1.2	0.7	1.6	1.0	0.2	0.1
Eye problems/disorders: Glaucoma	0.5	0.6	1.6	0.5	-1.1	0.9	-1.1	-1.3	0.8	-0.0	-0.2	-0.4	0.7
Number of operations (self-reported)	0.5	0.8	3.9	1.1	0.4	-2.0	-0.7	-0.5	-0.7	0.5	-0.2	-1.0	-0.2
Neuroticism (Nagel 2018)	0.4	1.0	4.1	0.3	0.5	-1.3	-0.4	-0.2	-1.3	0.0	-0.5	-1.4	-2.0
Worry (Nagel 2018)	0.4	0.8	3.3	-0.0	0.5	-1.2	-0.6	-0.4	-0.9	-0.5	-0.4	-0.8	-1.8
Neuroticism (2016)	0.4	0.6	2.7	-0.6	0.4	-0.7	0.5	0.6	-1.6	-0.4	-0.9	-0.5	-0.1
Primary Biliary Cirrhosis	0.4	0.5	1.5	0.1	-0.4	-1.2	-0.5	-0.2	-0.9	-0.4	-0.9	-1.2	0.2
Type 2 Diabetes (T2D) (2012)	0.4	0.5	1.5	0.9	1.2	-0.5	-0.6	-0.4	0.3	1.0	0.0	-0.1	0.6
Heel T-Score	0.4	2.8	5.0	-2.2	-1.8	-2.1	-0.5	-0.3	-2.0	-1.9	-2.1	-1.5	0.7
Allergy or Eczema	0.4	1.1	3.8	-1.9	-1.7	-1.7	0.8	0.5	0.3	-0.7	-0.2	0.3	0.3
Tanning	0.4	5.1	19.4	4.4	1.4	1.2	1.6	1.7	1.9	2.8	2.4	1.6	1.6
Hand grip strength (left)	0.4	1.2	7.5	1.3	-0.5	1.1	0.2	0.2	0.8	0.3	0.0	0.8	2.7
Sensitivity / hurt feelings	0.4	0.7	3.5	0.6	1.2	-0.7	-0.4	-0.1	-0.6	0.1	0.2	-0.8	-1.9
Angina	0.4	0.5	1.9	0.2	-0.1	-0.4	-1.1	-1.0	-0.1	0.1	-0.6	-0.8	1.4
Vitamin and mineral supplements	0.4	0.5	1.1	1.1	1.0	-0.7	-0.7	-0.4	-0.6	-0.2	-0.5	-1.0	0.3
Supplements: Zinc	0.4	0.4	1.8	-1.2	0.1	0.6	0.6	0.4	-0.1	-0.4	0.2	0.2	-1.3
Diabetes (mother)	0.4	0.6	3.9	0.4	0.1	-2.0	0.7	0.5	0.5	0.0	0.4	0.2	0.7
Trunk fat percentage	0.4	1.8	7.3	-2.7	-2.4	-0.5	-0.1	-0.1	-0.3	-1.5	-1.0	-0.6	0.8
Age when periods started (menarche)	0.4	1.1	4.2	2.0	0.7	-0.7	-1.0	-0.7	-0.9	0.3	-0.7	-0.8	1.4
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	2.0	-1.4	0.0	-0.9	-0.4	-0.7	0.3	-0.3	0.3	0.3	-0.3
Hayfever, allergic rhinitis or eczema	0.4	0.9	2.3	-1.2	-0.8	-0.9	1.5	1.2	0.6	0.2	0.9	1.2	-0.1
Trunk fat-free mass	0.4	2.3	7.3	-2.7	-1.7	1.9	-0.3	-0.3	-0.8	-2.3	-1.6	-0.4	0.5
Trunk predicted mass	0.4	2.4	7.7	-2.8	-1.7	1.9	-0.4	-0.4	-0.9	-2.4	-1.7	-0.5	0.4
Medication: Paracetamol	0.4	0.6	2.0	-0.5	1.3	-1.3	0.5	0.4	0.0	0.1	0.6	-0.2	-1.4
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	2.3	1.2	1.0	1.5	0.3	0.2	-0.0	0.7	0.5	1.2	0.0
Glaucoma (self-reported)	0.4	0.5	1.7	0.8	-1.3	0.7	-0.5	-0.6	1.0	0.4	0.5	0.4	0.5
Emphysema/chronic bronchitis	0.4	0.5	1.8	1.4	-0.3	-0.6	-0.7	-0.8	0.1	0.7	-0.3	-0.7	0.4
Medication: Blood pressure	0.4	0.7	1.3	-0.9	-0.8	-1.0	-1.1	-1.1	0.3	-0.5	-0.2	-1.0	-0.6
Medication: Omeprazole	0.4	0.5	1.8	0.6	0.5	-1.4	0.7	0.5	0.1	0.9	0.4	0.1	0.6
Alcohol intake frequency.	0.4	1.0	3.9	-0.6	2.0	-0.1	0.6	0.7	-0.0	0.6	1.0	1.0	-1.5
Commuting to job workplace: Car/motor vehicle	0.4	0.5	1.6	0.4	-0.1	-1.3	-0.5	-0.2	-1.2	-0.1	-0.7	-0.8	-0.1
Loneliness, isolation	0.4	0.6	2.0	-0.4	0.5	-1.4	0.6	0.8	-0.1	0.5	0.6	0.2	-1.3
Long-standing illness, disability or infirmity	0.4	0.6	3.1	-0.8	0.6	-1.8	-0.2	0.1	0.3	-1.1	0.1	0.2	-0.7
Asthma (self-reported)	0.4	0.8	4.4	-1.0	-0.4	-2.1	-0.1	-0.0	-0.9	-1.2	-0.8	-0.2	0.2
Medication: Gliclazide	0.4	0.4	1.0	0.2	0.1	-0.9	-1.0	-0.9	0.0	-0.4	-0.4	-0.5	0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	2.2	0.3	-0.2	0.1	-1.4	-1.5	-0.5	-0.9	-0.8	-1.5	-0.5
Number of self-reported non-cancer illnesses	0.4	0.6	4.3	-0.9	-0.6	-2.1	-0.2	-0.5	-0.2	-0.4	-0.3	-0.5	0.2
Commuting to job workplace: Public transport	0.4	0.4	1.6	0.9	-0.2	-1.3	0.9	0.8	-0.1	0.4	0.2	0.0	0.4
Myopia	0.4	0.6	1.5	-1.2	-0.6	-0.8	-0.4	-0.7	-0.7	-0.7	-0.6	-0.0	-1.0
Pain experienced in last month	0.4	0.7	1.7	1.1	-0.3	-0.4	0.6	1.0	0.1	1.3	1.0	0.3	-1.3
Pack years of smoking	0.4	0.6	2.7	0.8	0.9	-1.6	-0.2	0.1	0.1	0.9	0.7	0.1	-0.3
Depressed Affect (Nagel 2018)	0.3	0.7	2.0	0.5	0.8	-0.7	1.0	1.0	-0.5	1.1	0.6	-0.3	-1.4
Ovarian Cancer	0.3	0.4	0.8	0.4	0.6	0.7	0.2	0.1	0.9	0.9	0.9	0.4	-0.3
HDL Cholesterol	0.3	0.5	2.8	0.5	1.2	0.0	-0.0	0.1	-0.3	0.1	0.7	0.0	-1.7
Triglycerides	0.3	0.5	1.9	1.4	-0.1	-0.0	0.1	0.3	-0.5	1.3	-0.2	0.0	0.9
Ulcerative Colitis	0.3	0.5	2.0	-0.1	0.4	0.1	0.7	0.8	1.4	0.1	0.9	0.4	0.6
Blood Platelet Count	0.3	3.8	18.0	-4.2	-0.8	1.0	0.1	0.0	-0.8	-2.2	-0.5	0.7	-3.4
Hypothyroidism (self reported)	0.3	0.6	4.5	0.9	0.4	2.1	-0.0	0.0	0.4	0.3	0.1	-0.1	-0.3
Lung FVC	0.3	1.4	8.7	3.0	1.8	0.3	-0.8	-0.8	0.5	0.6	0.5	-0.0	0.1
Chronotype (morning person)	0.3	0.6	1.9	-0.9	-0.7	-0.3	1.0	1.0	0.0	0.6	0.1	0.9	1.4
Number of treatments/medications taken	0.3	0.6	3.3	-1.8	-1.2	-0.7	-0.5	-0.4	0.0	-0.7	-0.1	-0.2	-0.1
Ever had hysterectomy (womb removed)	0.3	0.3	2.5	-1.6	0.2	-0.2	-0.0	-0.4	0.2	-0.1	0.1	0.4	-0.5
Medication: Metformin	0.3	0.4	1.4	-0.2	-0.6	0.3	-0.8	-1.2	0.4	-0.5	-0.5	-0.5	0.7
Pack years adult smoking proportion	0.3	0.4	2.4	0.1	0.8	-1.5	-0.1	0.2	-0.4	0.5	0.4	-0.0	-0.7
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	1.4	0.8	0.1	0.0	0.4	0.3	0.4	1.2	0.9	0.6	0.4
Sitting height	0.3	1.9	5.8	0.8	0.3	2.4	1.1	0.9	1.7	1.8	1.5	1.2	0.8
Allergy	0.3	0.8	2.4	1.6	1.0	1.3	-1.0	-0.8	-0.0	0.4	-0.4	-0.8	0.5
Neuroticism score	0.3	0.6	2.5	0.1	0.5	-1.3	0.3	0.4	-0.9	0.3	-0.1	-0.8	-1.6
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.4	2.5	-0.4	0.9	-0.3	-0.6	-0.4	-0.1	0.4	0.2	-0.1	-1.6
Qualifications: A levels/AS levels or equivalent	0.3	0.6	3.6	1.9	0.3	-0.1	-0.1	-0.4	0.3	1.2	0.3	-0.1	0.5
Forced vital capacity (FVC), Best measure	0.3	1.0	4.2	2.0	1.7	0.4	0.0	-0.0	0.6	0.9	1.0	0.5	-0.2
Mean time to correctly identify matches	0.3	0.6	1.6	-0.4	-0.5	-1.3	0.7	0.9	0.6	0.7	0.7	1.0	0.4
Pulse rate, automated reading	0.3	0.9	4.3	-0.6	-0.9	0.3	-0.9	-1.1	0.2	-2.1	-0.9	-0.2	0.8
Illnesses of siblings: Diabetes	0.3	0.3	2.1	0.2	0.2	0.4	0.6	0.6	0.0	0.4	-0.0	0.2	1.4
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.7	3.2	-1.8	-0.5	1.2	0.4	0.1	-0.7	-0.9	-0.4	0.5	-0.3
Smoking status: Current	0.3	0.4	1.4	-0.3	-0.1	0.2	-0.9	-1.2	-0.3	-0.6	-0.6	-0.7	0.5
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	1.2	0.6	0.4	-1.1	0.4	0.1	-0.4	0.8	-0.0	-0.8	0.0
Major Depression (MDD)	0.2	0.3	1.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.1	1.2	0.0
Reaction Time	0.2	0.4	1.0	-0.7	-0.8	-0.6	0.8	1.0	0.4	0.1	0.3	0.7	0.1
Blood Eosinophil Count	0.2	1.2	3.9	1.3	-1.1	1.7	-0.6	-0.9	0.1	0.3	-0.9	-0.1	2.0
Blood Red Count	0.2	1.7	8.5	-0.2	2.9	-1.0	0.6	1.1	0.9	1.1	1.3	0.6	-1.4
Severe depression (siblings)	0.2	0.3	1.0	0.2	0.3	-0.8	0.4	0.3	-1.0	0.0	-0.6	0.0	0.7
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	2.8	0.3	-0.4	-0.0	0.9	0.9	0.0	0.4	0.2	0.7	1.7
Multivitamins +/- minerals	0.2	0.3	1.1	-0.7	-1.1	0.6	0.2	0.1	0.3	-0.2	0.2	0.5	-0.4
Forced vital capacity (FVC)	0.2	0.9	4.3	2.1	1.7	0.1	0.1	-0.0	0.5	0.9	0.7	0.3	0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.6	2.5	-0.6	-1.3	-0.5	-0.1	-0.3	-0.4	-0.3	-0.7	-0.3	1.6
Illnesses of siblings	0.2	0.3	1.0	1.0	0.7	-0.4	0.4	0.2	0.1	0.7	0.4	0.0	-0.4
Father’s age at death	0.2	0.2	0.7	0.4	0.7	-0.1	-0.3	-0.4	0.1	0.3	0.6	0.3	-0.8
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	1.1	0.5	-0.4	1.0	-0.0	0.2	-0.2	0.6	-0.1	0.2	0.8
Hair/balding pattern: Pattern 4	0.2	0.4	1.9	0.6	0.1	-0.6	-0.1	-0.4	0.7	0.7	0.4	0.6	1.4
Hypothyroidism/myxoedema (self-reported)	0.2	0.3	2.2	1.0	-0.1	1.5	-0.1	-0.1	-0.0	0.3	0.0	-0.2	-0.2
Medication: Ibuprofen	0.2	0.3	1.1	0.3	0.4	-0.1	-0.1	0.1	-0.9	0.4	-0.6	-0.0	1.1
Qualifications: nursing, teaching	0.2	0.4	2.5	1.6	0.1	-0.2	-0.1	0.0	0.5	0.6	0.7	0.1	0.2
Commuting to job workplace: Walk	0.2	0.2	0.9	-0.1	-0.6	0.9	0.2	-0.0	0.4	0.1	0.5	0.6	-0.2
Pain type(s) experienced in last month: Hip pain	0.2	0.2	0.6	0.7	0.5	-0.7	0.2	0.2	-0.3	0.5	-0.0	0.3	0.8
Schizophrenia vs Biploar Disorder	0.1	0.2	0.5	0.5	0.4	0.0	-0.5	-0.7	0.4	0.2	0.0	-0.1	-0.4
Blood White Count	0.1	0.6	1.2	0.3	-0.4	-0.1	0.7	1.1	0.9	0.9	1.1	1.0	-0.1
Average weekly fortified wine intake	0.1	0.1	0.4	-0.3	0.1	0.0	0.3	-0.2	-0.4	-0.4	-0.4	0.2	0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.2	0.2	0.4	-0.1	0.4	0.5	0.1	0.2	0.4	0.5	-0.3
Medication: Levothyroxine sodium	0.1	0.1	0.3	-0.4	-0.6	0.2	-0.1	-0.1	0.1	-0.3	-0.4	-0.3	0.3
Qualifications: None of the above	0.1	0.3	1.2	-1.1	0.0	-0.3	-0.5	-0.4	0.6	-0.4	0.0	0.2	0.6
Heart attack	0.1	0.1	0.5	0.4	0.0	-0.7	-0.5	-0.2	-0.2	0.4	0.0	-0.1	-0.1
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.6	-0.5	-0.7	-0.5	-0.0	-0.4	0.2	-0.1	0.0	-0.1	-0.3
Forced expiratory volume in 1-second (FEV1)	0.1	0.3	1.8	0.4	1.4	0.0	0.4	0.5	-0.1	-0.3	0.1	0.2	-0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	2.0	0.7	1.4	0.1	0.6	0.6	0.2	0.2	0.7	0.6	-0.3
Tense / ‘highly strung’	0.1	0.2	0.4	-0.5	-0.4	-0.1	0.6	0.6	0.2	-0.5	0.2	0.7	0.1
Qualifications: O levels/GCSEs or equivalent	0.1	0.1	0.6	-0.2	-0.2	-0.4	0.1	-0.2	-0.1	-0.2	-0.1	-0.1	-0.8
Wheeze or whistling in the chest in last year	0.1	0.2	0.5	0.5	-0.6	-0.4	0.6	0.7	-0.7	0.2	-0.3	0.2	0.5
Leg pain on walking	0.1	0.2	0.6	-0.8	0.1	-0.3	0.3	0.3	0.2	-0.6	-0.1	0.5	0.3
Illnesses of father: Heart disease	0.1	0.1	0.4	-0.0	-0.3	-0.3	0.2	0.5	-0.5	-0.2	-0.4	-0.3	0.7
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	0.6	0.5	-0.3	-0.6	-0.4	-0.1	-0.7	-0.0	-0.4	-0.7	-0.3
Illnesses of father: None of the above (group 1)	0.1	0.1	0.4	-0.1	0.6	0.6	-0.0	-0.2	-0.3	-0.4	-0.1	-0.3	-0.6
Average weekly champagne plus white wine intake	0.1	0.2	1.1	1.0	-0.1	0.5	-0.4	-0.1	0.5	0.2	0.2	-0.2	0.1
Illnesses of father: High blood pressure	0.1	0.1	0.3	-0.2	-0.6	-0.2	0.3	0.1	-0.5	0.1	-0.1	0.2	-0.5
Supplements: Calcium	0.1	0.2	0.5	-0.0	0.4	-0.5	0.2	0.2	0.1	0.7	0.3	0.6	-0.5
Heart attack/myocardial infarction (self-reported)	0.1	0.2	0.8	0.5	0.0	-0.9	-0.6	-0.4	-0.3	0.5	-0.0	-0.2	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Hair Pigment	0.0	0.7	1.4	-0.8	-0.8	-0.0	-0.8	-0.7	-0.5	-1.1	-1.2	-1.2	-0.2
Fed-up feelings	0.0	0.1	0.3	-0.1	-0.5	-0.5	0.1	-0.1	-0.2	0.1	-0.2	-0.5	-0.1
Had major operations	0.0	0.1	0.3	0.2	0.0	-0.2	0.0	0.1	-0.2	0.3	0.1	0.1	0.5

Hub : Genes

AP2A2

Models

Trait associations