[Hub]/) : Traits : Whole body fat-free mass :

chr11:46,010,847-48,783,497

Best TWAS P=9.45e-13 · Best GWAS P=1.07e-11 conditioned to 0.128

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PTPRJ 0.05 0.05 lasso 2 0.04 3.9e-04 6.3 6.1 1.3e-09 0.59 0.01 0.97 FALSE
2 GTEx Artery Aorta MADD 0.09 0.03 enet 22 0.04 1.9e-03 -4.9 5.7 9.8e-09 0.45 0.09 0.39 FALSE
3 GTEx Artery Aorta PACSIN3 0.10 0.04 lasso 4 0.03 1.1e-02 4.0 6.1 1.1e-09 0.45 0.10 0.73 FALSE
4 GTEx Breast Mammary Tissue (Female) PSMC3 0.02 0.01 lasso 1 0.04 2.5e-02 5.4 -5.4 5.4e-08 -0.72 0.03 0.17 FALSE
5 GTEx Esophagus Mucosa PACSIN3 0.24 0.19 lasso 8 0.21 7.5e-14 4.1 5.3 1.3e-07 0.38 0.84 0.15 FALSE
6 GTEx Lung PSMC3 0.07 0.02 lasso 2 0.03 3.6e-03 5.3 -5.3 9.7e-08 -0.46 0.06 0.66 FALSE
7 GTEx Muscle Skeletal SLC39A13 0.05 0.01 lasso 3 0.01 8.5e-02 5.3 -5.8 7.4e-09 -0.59 0.05 0.52 FALSE
8 GTEx Prostate PSMC3 0.21 0.10 lasso 6 0.20 7.9e-06 5.3 -6.5 1.1e-10 -0.56 0.05 0.66 FALSE
9 GTEx Skin Not Sun Exposed Suprapubic LRP4 0.13 0.00 lasso 7 0.02 3.5e-02 5.4 6.2 6.4e-10 0.53 0.06 0.56 FALSE
10 GTEx Skin Not Sun Exposed Suprapubic PACSIN3 0.11 0.05 lasso 3 0.10 3.4e-06 4.1 5.2 2.4e-07 0.36 0.42 0.34 FALSE
11 GTEx Skin Sun Exposed Lower leg PSMC3 0.20 0.05 lasso 7 0.10 1.2e-08 5.4 -5.4 5.9e-08 -0.68 0.08 0.91 FALSE
12 GTEx Skin Sun Exposed Lower leg ARHGAP1 0.08 0.01 lasso 5 0.02 1.4e-02 4.7 -5.2 1.9e-07 -0.29 0.02 0.90 FALSE
13 METSIM Adipose RAPSN 0.11 0.01 enet 21 0.06 7.9e-09 3.7 5.8 5.1e-09 0.41 0.84 0.15 FALSE
14 NTR Blood MADD 0.01 0.01 enet 8 0.01 4.7e-03 5.5 6.0 1.6e-09 0.31 0.04 0.73 FALSE
15 ROSMAP Brain Pre-frontal Cortex CELF1 0.03 0.01 bslmm 289 0.01 2.9e-02 6.0 7.1 9.4e-13 0.83 0.02 0.87 TRUE
16 ROSMAP Brain Pre-frontal Cortex PSMC3 0.15 0.08 bslmm 285 0.10 5.1e-13 5.2 -5.5 3.6e-08 -0.54 0.07 0.92 FALSE
17 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma SLC39A13 0.06 0.01 blup 58 0.04 9.3e-04 4.9 -5.8 7.6e-09 -0.56 0.01 0.72 FALSE