[Hub]/) : Traits : Whole body fat-free mass : ← →

chr20:19,318,837-22,065,466

Best TWAS P=5.14e-16 · Best GWAS P=1.31e-17 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	C20orf26	0.20	0.17	lasso	6	0.18	4.9e-21	-5.7	5.5	3.2e-08	-0.06	0.08	0.92	FALSE
2	CommonMind	Brain Pre-frontal Cortex	INSM1	0.07	0.00	bslmm	522	0.02	2.2e-03	3.9	5.8	6.4e-09	-0.01	0.08	0.12	TRUE
3	CommonMind	Brain Pre-frontal Cortex	PLK1S1	0.08	0.01	lasso	3	0.04	1.1e-05	7.1	6.6	5.2e-11	0.82	0.02	0.98	FALSE
4	GTEx	Artery Tibial	PLK1S1	0.07	0.08	enet	10	0.08	4.0e-07	8.4	8.1	5.1e-16	0.97	0.01	0.99	TRUE
5	GTEx	Esophagus Mucosa	PLK1S1	0.11	0.11	lasso	5	0.09	7.8e-07	6.6	6.5	7.2e-11	0.83	0.13	0.87	FALSE
6	GTEx	Heart Atrial Appendage	PLK1S1	0.15	-0.01	lasso	4	0.00	6.1e-01	1.2	5.8	7.0e-09	0.56	0.05	0.41	FALSE
7	GTEx	Skin Not Sun Exposed Suprapubic	PLK1S1	0.21	0.09	lasso	6	0.12	5.3e-07	8.0	7.0	1.9e-12	0.93	0.07	0.93	FALSE
8	GTEx	Skin Sun Exposed Lower leg	PLK1S1	0.15	0.13	enet	10	0.15	3.9e-12	6.5	6.1	8.4e-10	0.83	0.92	0.08	FALSE
9	GTEx	Testis	PLK1S1	0.64	0.34	enet	33	0.39	1.0e-18	6.5	7.1	9.5e-13	0.79	0.70	0.30	FALSE
10	GTEx	Whole Blood	PLK1S1	0.08	0.04	enet	9	0.02	4.0e-03	6.5	7.2	4.0e-13	0.89	0.07	0.93	FALSE
11	YFS	Blood	CRNKL1	0.21	0.25	enet	18	0.27	2.3e-89	-5.7	-5.4	8.1e-08	0.03	0.07	0.93	FALSE
12	YFS	Blood	XRN2	0.34	0.61	lasso	10	0.61	3.5e-258	5.1	5.2	2.3e-07	0.49	1.00	0.00	FALSE
13	The Cancer Genome Atlas	Breast Invasive Carcinoma	PLK1S1	0.05	0.07	enet	9	0.07	5.5e-15	6.3	7.0	3.4e-12	0.88	0.16	0.84	FALSE
14	The Cancer Genome Atlas	Lung Adenocarcinoma	PLK1S1	0.04	0.03	blup	64	0.04	4.0e-05	6.5	7.6	3.3e-14	0.88	0.12	0.87	FALSE
15	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	PLK1S1	0.09	0.02	blup	64	0.05	3.1e-03	7.1	7.7	1.3e-14	0.78	0.03	0.52	FALSE
16	The Cancer Genome Atlas	Prostate Adenocarcinoma	PLK1S1	0.19	0.12	enet	14	0.13	4.3e-13	6.6	6.8	1.0e-11	0.80	0.91	0.09	FALSE
17	The Cancer Genome Atlas	Thyroid Carcinoma	PLK1S1	0.06	0.04	lasso	3	0.04	1.5e-04	6.6	6.8	1.2e-11	0.85	0.15	0.60	FALSE