[Hub]/) : Traits : Whole body fat-free mass :

chr5:41,211,789-44,208,409

Best TWAS P=2.4e-23 · Best GWAS P=1.62e-23 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex GHR 0.25 0.07 bslmm 382 0.13 2.6e-15 -6.7 6.9 4.3e-12 0.20 0.21 0.79 FALSE
2 GTEx Adipose Subcutaneous CCDC152 0.09 0.04 lasso 4 0.02 6.4e-03 9.8 9.8 1.2e-22 0.46 0.04 0.96 FALSE
3 GTEx Adipose Visceral Omentum CCDC152 0.09 0.06 lasso 9 0.05 1.9e-03 9.6 9.1 8.6e-20 0.45 0.04 0.76 FALSE
4 GTEx Artery Aorta CCDC152 0.31 0.24 lasso 8 0.24 2.5e-13 9.6 8.9 7.4e-19 0.45 0.04 0.96 FALSE
5 GTEx Artery Coronary CCDC152 0.20 0.13 lasso 2 0.12 7.7e-05 9.6 9.6 5.2e-22 0.46 0.04 0.94 FALSE
6 GTEx Artery Tibial CCDC152 0.22 0.17 enet 35 0.18 1.8e-14 9.6 7.6 2.2e-14 0.43 0.04 0.96 FALSE
7 GTEx Brain Caudate basal ganglia C5orf34 0.14 -0.01 enet 14 0.00 3.3e-01 3.2 5.4 6.5e-08 0.07 0.04 0.28 TRUE
8 GTEx Brain Frontal Cortex BA9 GHR 0.14 0.02 lasso 9 0.06 9.9e-03 7.6 -5.8 7.3e-09 -0.31 0.13 0.05 TRUE
9 GTEx Breast Mammary Tissue (Female) SEPP1 0.15 0.00 enet 29 0.02 1.0e-01 -2.1 -5.5 4.6e-08 -0.23 0.06 0.12 TRUE
10 GTEx Esophagus Muscularis CCDC152 0.13 0.09 lasso 8 0.10 7.9e-07 8.5 8.3 8.1e-17 0.48 0.06 0.94 TRUE
11 GTEx Nerve Tibial CCDC152 0.16 0.06 enet 25 0.06 2.9e-05 9.6 6.4 1.7e-10 0.19 0.06 0.93 TRUE
12 GTEx Stomach SERBP1P6 0.12 0.03 enet 16 0.01 6.7e-02 -4.7 7.7 1.8e-14 0.24 0.08 0.12 FALSE
13 GTEx Thyroid GHR 0.08 0.04 enet 25 0.04 2.5e-04 8.5 5.2 1.9e-07 0.33 0.07 0.52 FALSE
14 GTEx Thyroid C5orf34 0.08 0.08 lasso 3 0.06 1.4e-05 5.0 5.2 1.7e-07 0.08 0.00 0.99 FALSE
15 GTEx Thyroid CCDC152 0.10 0.07 lasso 4 0.04 4.2e-04 9.6 9.7 3.8e-22 0.45 0.04 0.95 FALSE
16 ROSMAP Brain Pre-frontal Cortex ZNF131 0.18 0.06 lasso 15 0.12 3.3e-15 -3.9 5.2 2.5e-07 0.05 1.00 0.00 FALSE
17 ROSMAP Brain Pre-frontal Cortex CCDC152 0.20 0.09 lasso 10 0.09 5.2e-12 2.9 5.8 6.9e-09 0.17 0.99 0.01 FALSE
18 ROSMAP Brain Pre-frontal Cortex C5orf51 0.03 0.01 bslmm 298 0.02 1.9e-03 -3.3 5.4 6.9e-08 0.12 0.13 0.58 TRUE
19 ROSMAP Brain Pre-frontal Cortex SEPP1 0.18 0.19 lasso 11 0.21 1.3e-26 9.1 -9.7 3.6e-22 -0.48 0.03 0.97 FALSE
20 YFS Blood CCDC152 0.07 0.06 enet 16 0.06 2.0e-19 9.8 9.9 2.4e-23 0.47 0.03 0.97 TRUE
21 The Cancer Genome Atlas Breast Invasive Carcinoma CCDC152 0.14 0.02 blup 40 0.03 2.5e-06 9.1 -5.1 3.0e-07 -0.38 0.18 0.58 TRUE
22 The Cancer Genome Atlas Breast Invasive Carcinoma SEPP1 0.01 0.00 enet 7 0.01 1.5e-03 9.2 -7.5 7.1e-14 -0.39 0.02 0.50 TRUE
23 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CCDC152 0.06 0.06 blup 40 0.07 1.6e-08 9.0 -9.6 5.4e-22 -0.43 0.03 0.97 FALSE
24 The Cancer Genome Atlas Prostate Adenocarcinoma CCDC152 0.15 0.12 lasso 6 0.12 1.0e-12 9.2 -9.2 2.3e-20 -0.46 0.38 0.62 FALSE
25 The Cancer Genome Atlas Prostate Adenocarcinoma GHR 0.12 0.11 enet 6 0.13 2.5e-13 -7.9 -8.7 3.5e-18 -0.26 1.00 0.00 TRUE
26 The Cancer Genome Atlas Prostate Adenocarcinoma SEPP1 0.06 0.02 blup 38 0.04 5.2e-05 8.5 -8.8 8.7e-19 -0.40 0.21 0.72 FALSE
27 The Cancer Genome Atlas Thyroid Carcinoma MGC42105 0.04 0.01 blup 63 0.01 4.3e-02 -3.8 -5.4 5.7e-08 -0.10 0.00 0.05 TRUE