[Hub]/) : Traits : Whole body fat-free mass : ← →

chr5:41,211,789-44,208,409

Best TWAS P=2.4e-23 · Best GWAS P=1.62e-23 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
20	YFS	Blood	CCDC152	0.07	0.06	enet	16	0.06	2.0e-19	9.8	9.9	2.4e-23	0.47	0.03	0.97	TRUE
25	The Cancer Genome Atlas	Prostate Adenocarcinoma	GHR	0.12	0.11	enet	6	0.13	2.5e-13	-7.9	-8.7	3.5e-18	-0.26	1.00	0.00	TRUE
10	GTEx	Esophagus Muscularis	CCDC152	0.13	0.09	lasso	8	0.10	7.9e-07	8.5	8.3	8.1e-17	0.48	0.06	0.94	TRUE
22	The Cancer Genome Atlas	Breast Invasive Carcinoma	SEPP1	0.01	0.00	enet	7	0.01	1.5e-03	9.2	-7.5	7.1e-14	-0.39	0.02	0.50	TRUE
11	GTEx	Nerve Tibial	CCDC152	0.16	0.06	enet	25	0.06	2.9e-05	9.6	6.4	1.7e-10	0.19	0.06	0.93	TRUE
8	GTEx	Brain Frontal Cortex BA9	GHR	0.14	0.02	lasso	9	0.06	9.9e-03	7.6	-5.8	7.3e-09	-0.31	0.13	0.05	TRUE
9	GTEx	Breast Mammary Tissue (Female)	SEPP1	0.15	0.00	enet	29	0.02	1.0e-01	-2.1	-5.5	4.6e-08	-0.23	0.06	0.12	TRUE
27	The Cancer Genome Atlas	Thyroid Carcinoma	MGC42105	0.04	0.01	blup	63	0.01	4.3e-02	-3.8	-5.4	5.7e-08	-0.10	0.00	0.05	TRUE
7	GTEx	Brain Caudate basal ganglia	C5orf34	0.14	-0.01	enet	14	0.00	3.3e-01	3.2	5.4	6.5e-08	0.07	0.04	0.28	TRUE
18	ROSMAP	Brain Pre-frontal Cortex	C5orf51	0.03	0.01	bslmm	298	0.02	1.9e-03	-3.3	5.4	6.9e-08	0.12	0.13	0.58	TRUE
21	The Cancer Genome Atlas	Breast Invasive Carcinoma	CCDC152	0.14	0.02	blup	40	0.03	2.5e-06	9.1	-5.1	3.0e-07	-0.38	0.18	0.58	TRUE
2	GTEx	Adipose Subcutaneous	CCDC152	0.09	0.04	lasso	4	0.02	6.4e-03	9.8	9.8	1.2e-22	0.46	0.04	0.96	FALSE
19	ROSMAP	Brain Pre-frontal Cortex	SEPP1	0.18	0.19	lasso	11	0.21	1.3e-26	9.1	-9.7	3.6e-22	-0.48	0.03	0.97	FALSE
15	GTEx	Thyroid	CCDC152	0.10	0.07	lasso	4	0.04	4.2e-04	9.6	9.7	3.8e-22	0.45	0.04	0.95	FALSE
5	GTEx	Artery Coronary	CCDC152	0.20	0.13	lasso	2	0.12	7.7e-05	9.6	9.6	5.2e-22	0.46	0.04	0.94	FALSE
23	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CCDC152	0.06	0.06	blup	40	0.07	1.6e-08	9.0	-9.6	5.4e-22	-0.43	0.03	0.97	FALSE
24	The Cancer Genome Atlas	Prostate Adenocarcinoma	CCDC152	0.15	0.12	lasso	6	0.12	1.0e-12	9.2	-9.2	2.3e-20	-0.46	0.38	0.62	FALSE
3	GTEx	Adipose Visceral Omentum	CCDC152	0.09	0.06	lasso	9	0.05	1.9e-03	9.6	9.1	8.6e-20	0.45	0.04	0.76	FALSE
4	GTEx	Artery Aorta	CCDC152	0.31	0.24	lasso	8	0.24	2.5e-13	9.6	8.9	7.4e-19	0.45	0.04	0.96	FALSE
26	The Cancer Genome Atlas	Prostate Adenocarcinoma	SEPP1	0.06	0.02	blup	38	0.04	5.2e-05	8.5	-8.8	8.7e-19	-0.40	0.21	0.72	FALSE
12	GTEx	Stomach	SERBP1P6	0.12	0.03	enet	16	0.01	6.7e-02	-4.7	7.7	1.8e-14	0.24	0.08	0.12	FALSE
6	GTEx	Artery Tibial	CCDC152	0.22	0.17	enet	35	0.18	1.8e-14	9.6	7.6	2.2e-14	0.43	0.04	0.96	FALSE
1	CommonMind	Brain Pre-frontal Cortex	GHR	0.25	0.07	bslmm	382	0.13	2.6e-15	-6.7	6.9	4.3e-12	0.20	0.21	0.79	FALSE
17	ROSMAP	Brain Pre-frontal Cortex	CCDC152	0.20	0.09	lasso	10	0.09	5.2e-12	2.9	5.8	6.9e-09	0.17	0.99	0.01	FALSE
14	GTEx	Thyroid	C5orf34	0.08	0.08	lasso	3	0.06	1.4e-05	5.0	5.2	1.7e-07	0.08	0.00	0.99	FALSE
13	GTEx	Thyroid	GHR	0.08	0.04	enet	25	0.04	2.5e-04	8.5	5.2	1.9e-07	0.33	0.07	0.52	FALSE
16	ROSMAP	Brain Pre-frontal Cortex	ZNF131	0.18	0.06	lasso	15	0.12	3.3e-15	-3.9	5.2	2.5e-07	0.05	1.00	0.00	FALSE