[Hub]/) : Traits : Impedance of whole body :

chr8:37,329,315-38,989,813

Best TWAS P=4.68e-10 · Best GWAS P=6.53e-10 conditioned to 0.0706

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DDHD2 0.04 0.04 bslmm 286 0.04 2.0e-05 6.2 5.9 4.0e-09 0.93 0.02 0.98 FALSE
2 GTEx Adrenal Gland DDHD2 0.25 0.21 lasso 2 0.19 1.7e-07 6.0 6.1 1.0e-09 0.96 0.03 0.97 FALSE
3 GTEx Artery Tibial DDHD2 0.07 0.07 lasso 2 0.05 7.3e-05 6.0 6.0 1.7e-09 0.97 0.03 0.97 FALSE
4 GTEx Breast Mammary Tissue RP11-350N15.5 0.08 0.03 enet 12 0.02 1.9e-02 4.6 -5.9 2.9e-09 -0.87 0.03 0.91 FALSE
5 GTEx Breast Mammary Tissue (Female) RP11-350N15.5 0.12 0.10 lasso 2 0.07 3.9e-03 5.9 -6.0 2.0e-09 -0.96 0.03 0.86 FALSE
6 GTEx Colon Sigmoid DDHD2 0.15 0.15 lasso 3 0.12 7.5e-05 6.2 6.2 7.4e-10 1.00 0.02 0.95 FALSE
7 GTEx Esophagus Muscularis DDHD2 0.12 0.13 lasso 2 0.12 5.7e-08 5.5 5.5 4.1e-08 0.98 0.05 0.95 FALSE
8 GTEx Liver DDHD2 0.29 0.01 lasso 5 -0.01 5.4e-01 5.9 5.8 6.7e-09 0.88 0.03 0.66 FALSE
9 GTEx Nerve Tibial DDHD2 0.15 0.16 enet 26 0.16 2.3e-11 6.1 5.5 3.8e-08 0.94 0.02 0.98 FALSE
10 GTEx Pituitary DDHD2 0.25 0.22 lasso 3 0.17 3.9e-05 5.9 5.2 1.7e-07 0.91 0.03 0.92 FALSE
11 GTEx Prostate DDHD2 0.38 0.18 lasso 7 0.17 5.4e-05 5.5 5.5 3.7e-08 0.98 0.04 0.96 FALSE
12 GTEx Spleen DDHD2 0.17 0.17 lasso 2 0.11 7.8e-04 6.0 6.1 1.4e-09 0.98 0.03 0.90 FALSE
13 GTEx Stomach DDHD2 0.13 0.06 lasso 2 0.06 1.1e-03 5.5 5.6 2.8e-08 0.94 0.04 0.88 FALSE
14 GTEx Thyroid DDHD2 0.11 0.10 lasso 4 0.09 3.8e-07 5.5 5.5 3.5e-08 0.98 0.04 0.96 FALSE
15 GTEx Thyroid RP11-90P5.2 0.09 0.00 enet 12 0.01 1.1e-01 5.6 -6.2 4.7e-10 -0.83 0.04 0.83 TRUE
16 NTR Blood BAG4 0.01 0.01 blup 253 0.01 3.9e-03 5.5 -5.7 1.5e-08 -0.93 0.04 0.94 FALSE
17 ROSMAP Brain Pre-frontal Cortex DDHD2 0.05 0.01 lasso 5 0.02 1.6e-03 5.3 5.2 2.0e-07 0.87 0.07 0.87 FALSE
18 ROSMAP Brain Pre-frontal Cortex PPAPDC1B 0.06 0.08 enet 14 0.09 4.0e-11 6.0 5.8 5.9e-09 0.96 0.04 0.96 FALSE
19 ROSMAP Brain Pre-frontal Cortex LSM1 0.09 0.16 lasso 6 0.16 7.3e-20 5.5 -5.6 2.7e-08 -0.98 0.11 0.89 FALSE
20 ROSMAP Brain Pre-frontal Cortex RPS20P22 0.04 0.00 blup 267 0.02 2.9e-03 5.9 5.9 3.3e-09 0.74 0.03 0.86 FALSE
21 YFS Blood BAG4 0.01 0.01 bslmm 234 0.00 2.6e-02 5.0 5.5 2.9e-08 0.86 0.04 0.79 FALSE
22 YFS Blood LSM1 0.02 0.00 bslmm 218 0.01 4.1e-04 4.2 -5.7 1.5e-08 -0.82 0.05 0.93 FALSE
23 The Cancer Genome Atlas Breast Invasive Carcinoma DDHD2 0.01 0.01 blup 21 0.01 2.3e-03 6.0 6.0 2.0e-09 0.98 0.01 0.80 FALSE
24 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DDHD2 0.03 0.03 blup 21 0.03 3.5e-04 5.4 6.0 2.0e-09 0.98 0.02 0.98 FALSE
25 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PPAPDC1B 0.02 0.00 blup 18 0.01 4.2e-02 6.0 6.0 1.7e-09 0.95 0.01 0.57 FALSE
26 The Cancer Genome Atlas Pancreatic Adenocarcinoma DDHD2 0.07 0.05 blup 21 0.05 2.7e-03 6.2 5.9 3.8e-09 0.99 0.01 0.80 FALSE
27 The Cancer Genome Atlas Prostate Adenocarcinoma DDHD2 0.11 0.08 lasso 3 0.08 1.9e-08 6.2 6.2 6.5e-10 1.00 0.01 0.99 FALSE
28 The Cancer Genome Atlas Thyroid Carcinoma DDHD2 0.02 0.01 blup 21 0.01 2.4e-02 6.0 5.9 3.0e-09 0.98 0.01 0.76 FALSE