Best TWAS P=2.79e-17 · Best GWAS P=2.12e-22 conditioned to 7.73e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | AMPD3 | 0.20 | 0.02 | lasso | 8 | 0.01 | 5.5e-02 | 6.32 | -6.1 | 9.0e-10 | -0.22 | 0.30 | 0.04 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | SBF2 | 0.16 | 0.14 | lasso | 4 | 0.14 | 6.8e-11 | -5.47 | 6.3 | 4.0e-10 | 0.39 | 1.00 | 0.00 | FALSE |
| 3 | GTEx | Prostate | SBF2 | 0.21 | 0.05 | lasso | 7 | 0.03 | 6.7e-02 | -7.28 | -8.4 | 4.1e-17 | -0.86 | 0.04 | 0.76 | FALSE |
| 4 | GTEx | Testis | SBF2 | 0.10 | 0.01 | lasso | 5 | 0.02 | 5.0e-02 | -6.67 | 7.4 | 1.7e-13 | 0.82 | 0.08 | 0.77 | FALSE |
| 5 | METSIM | Adipose | AMPD3 | 0.06 | 0.03 | enet | 14 | 0.05 | 7.8e-08 | -5.58 | -5.6 | 2.0e-08 | -0.08 | 0.96 | 0.00 | TRUE |
| 6 | NTR | Blood | ADM | 0.04 | 0.04 | enet | 13 | 0.04 | 1.6e-13 | -7.26 | 8.5 | 2.8e-17 | 0.88 | 0.16 | 0.84 | TRUE |
| 7 | NTR | Blood | WEE1 | 0.02 | 0.00 | bslmm | 367 | 0.00 | 1.0e-02 | 0.94 | 5.8 | 8.5e-09 | 0.33 | 0.10 | 0.19 | FALSE |
| 8 | ROSMAP | Brain Pre-frontal Cortex | SBF2-AS1 | 0.03 | 0.00 | bslmm | 362 | 0.01 | 4.4e-03 | 1.80 | -6.6 | 3.5e-11 | -0.59 | 0.04 | 0.66 | FALSE |
| 9 | YFS | Blood | ADM | 0.08 | 0.11 | enet | 25 | 0.12 | 9.4e-36 | -7.44 | 8.0 | 1.0e-15 | 0.85 | 0.98 | 0.02 | FALSE |
| 10 | YFS | Blood | SWAP70 | 0.09 | 0.07 | bslmm | 379 | 0.08 | 1.6e-24 | 4.73 | 5.3 | 9.0e-08 | 0.32 | 1.00 | 0.00 | FALSE |