[Hub]/) : Traits : Impedance of whole body :

chr1:172,881,827-175,663,031

Best TWAS P=4.4e-10 · Best GWAS P=2.75e-10 conditioned to 0.173

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ANKRD45 0.11 0.11 bslmm 303 0.12 7.5e-14 -5.1 5.4 5.2e-08 -0.82 0.78 0.22 FALSE
2 GTEx Adrenal Gland RC3H1 0.12 0.06 lasso 2 0.06 3.2e-03 -5.9 6.0 1.6e-09 -0.98 0.04 0.80 FALSE
3 GTEx Artery Tibial RC3H1 0.09 0.07 lasso 2 0.07 2.6e-06 -5.9 5.9 2.8e-09 -0.98 0.04 0.96 FALSE
4 GTEx Breast Mammary Tissue RC3H1 0.17 0.05 enet 30 0.05 2.2e-03 -5.8 5.8 6.0e-09 -0.77 0.05 0.92 FALSE
5 GTEx Breast Mammary Tissue (Male) RC3H1 0.07 0.11 enet 3 0.07 9.9e-03 -6.2 6.2 6.1e-10 -1.00 0.03 0.59 FALSE
6 GTEx Breast Mammary Tissue (Female) RABGAP1L 0.19 0.00 lasso 3 0.01 2.0e-01 -6.1 -6.0 1.8e-09 0.92 0.06 0.42 FALSE
7 GTEx Esophagus Muscularis RC3H1 0.10 0.08 lasso 13 0.06 1.2e-04 -6.1 6.0 1.5e-09 -0.98 0.03 0.97 FALSE
8 GTEx Nerve Tibial RC3H1 0.09 0.06 enet 7 0.07 7.0e-06 -6.0 6.0 2.2e-09 -0.97 0.04 0.95 FALSE
9 GTEx Testis RC3H1 0.13 0.03 enet 24 0.06 8.0e-04 -6.0 5.5 3.8e-08 -0.88 0.06 0.91 FALSE
10 METSIM Adipose DARS2 0.04 0.01 blup 289 0.03 4.6e-05 -5.9 5.4 7.5e-08 -0.76 0.08 0.91 FALSE
11 METSIM Adipose SERPINC1 0.10 0.09 bslmm 271 0.09 1.2e-13 -5.9 -6.0 2.4e-09 0.95 0.05 0.95 FALSE
12 The Cancer Genome Atlas Bladder Urothelial Carcinoma MRPS14 0.12 0.05 lasso 3 0.03 6.5e-04 -5.4 -5.4 7.3e-08 0.95 0.00 0.99 FALSE
13 The Cancer Genome Atlas Breast Invasive Carcinoma CACYBP 0.11 0.04 lasso 3 0.03 9.3e-08 -5.1 -5.2 2.5e-07 0.96 0.00 1.00 FALSE
14 The Cancer Genome Atlas Breast Invasive Carcinoma RABGAP1L 0.07 0.01 lasso 3 0.01 1.2e-02 -5.4 -5.5 4.3e-08 0.97 0.03 0.94 FALSE
15 The Cancer Genome Atlas Breast Invasive Carcinoma SERPINC1 0.14 0.09 blup 47 0.09 1.2e-17 -5.9 -6.2 4.4e-10 0.93 0.01 0.99 TRUE
16 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma DARS2 0.14 0.00 blup 37 0.01 8.2e-02 -6.0 -5.6 2.1e-08 0.75 0.00 0.44 FALSE
17 The Cancer Genome Atlas Colon Adenocarcinoma SERPINC1 0.10 0.06 blup 47 0.06 1.8e-04 -4.8 -5.4 8.0e-08 0.76 0.02 0.78 FALSE
18 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SERPINC1 0.13 0.03 blup 47 0.03 1.7e-04 -6.0 -5.8 8.6e-09 0.93 0.01 0.99 FALSE
19 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma SERPINC1 0.31 0.07 lasso 2 0.05 6.8e-04 -5.8 -5.8 6.6e-09 0.93 0.01 0.98 FALSE
20 The Cancer Genome Atlas Brain Lower Grade Glioma SERPINC1 0.06 0.02 blup 48 0.02 1.7e-03 -5.9 -5.3 1.2e-07 0.92 0.01 0.95 FALSE
21 The Cancer Genome Atlas Liver Hepatocellular Carcinoma RC3H1 0.15 0.00 blup 58 0.03 1.8e-02 -6.0 -5.3 9.5e-08 0.89 0.02 0.57 FALSE
22 The Cancer Genome Atlas Lung Adenocarcinoma CACYBP 0.19 0.00 lasso 2 0.00 7.2e-01 -5.1 -5.1 3.0e-07 0.96 0.00 0.98 FALSE
23 The Cancer Genome Atlas Lung Adenocarcinoma SERPINC1 0.08 0.04 blup 48 0.05 5.8e-07 -6.0 -6.1 8.4e-10 0.84 0.01 0.99 FALSE
24 The Cancer Genome Atlas Lung Adenocarcinoma ZBTB37 0.07 0.00 blup 47 0.03 2.2e-04 3.0 -5.3 1.1e-07 0.66 0.02 0.54 FALSE
25 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma CACYBP 0.11 0.05 lasso 2 0.04 9.6e-04 -5.4 -5.3 9.8e-08 0.95 0.00 0.97 FALSE
26 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma MRPS14 0.12 0.01 lasso 4 0.01 1.1e-01 -5.4 -5.8 5.0e-09 0.94 0.00 0.93 FALSE
27 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma SERPINC1 0.32 0.11 enet 10 0.12 1.6e-05 -6.0 -5.6 2.5e-08 0.84 0.01 0.97 FALSE
28 The Cancer Genome Atlas Prostate Adenocarcinoma SERPINC1 0.08 0.01 blup 47 0.03 1.6e-04 -5.8 -6.1 1.2e-09 0.77 0.01 0.87 FALSE
29 The Cancer Genome Atlas Soft Tissue Sarcoma SERPINC1 0.12 0.08 lasso 5 0.08 2.4e-05 -6.0 -5.7 9.9e-09 0.91 0.01 0.98 FALSE
30 The Cancer Genome Atlas Stomach Adenocarcinoma SERPINC1 0.09 0.04 lasso 5 0.04 5.8e-04 -6.0 -5.5 3.3e-08 0.96 0.01 0.98 FALSE
31 The Cancer Genome Atlas Testicular Germ Cell Tumors RC3H1 0.13 -0.01 blup 58 0.01 1.4e-01 -5.9 -5.7 1.2e-08 0.80 0.01 0.25 FALSE