[Hub]/) : Traits : Impedance of whole body : ← →

chr1:153,973,171-156,405,037

Best TWAS P=3.25e-36 · Best GWAS P=3.21e-36 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	PBXIP1	0.06	0.04	lasso	5	0.02	5.8e-03	4.87	-5.5	4.8e-08	0.25	0.61	0.02	FALSE
2	GTEx	Brain Cerebellar Hemisphere	DAP3	0.13	0.12	lasso	2	0.13	2.8e-04	5.69	5.8	8.4e-09	-0.02	0.06	0.63	FALSE
3	GTEx	Brain Cerebellar Hemisphere	DCST2	0.45	0.10	lasso	6	0.16	6.6e-05	5.31	-10.4	4.0e-25	0.75	0.01	0.96	FALSE
4	GTEx	Brain Cerebellum	DCST2	0.48	0.27	lasso	9	0.31	6.0e-10	4.74	-5.8	6.6e-09	0.42	0.84	0.12	FALSE
5	GTEx	Brain Nucleus accumbens basal ganglia	DCST2	0.28	0.04	lasso	5	0.13	2.0e-04	-12.57	-8.9	5.3e-19	0.69	0.02	0.90	FALSE
6	GTEx	Brain Putamen basal ganglia	DCST2	0.56	0.05	enet	11	0.10	2.8e-03	5.31	-6.2	6.7e-10	0.47	0.18	0.58	FALSE
7	GTEx	Breast Mammary Tissue (Female)	FAM189B	0.05	-0.01	lasso	2	0.00	4.8e-01	6.98	-7.0	3.3e-12	0.09	0.04	0.07	FALSE
8	GTEx	Esophagus Mucosa	ADAM15	0.11	0.02	enet	16	0.04	1.5e-03	5.08	5.2	2.1e-07	-0.43	0.13	0.78	FALSE
9	GTEx	Esophagus Mucosa	MUC1	0.17	0.20	lasso	4	0.18	5.6e-12	7.61	7.3	3.4e-13	-0.12	1.00	0.00	TRUE
10	GTEx	Nerve Tibial	PBXIP1	0.08	0.02	enet	9	0.04	5.3e-04	2.62	-5.6	2.3e-08	0.31	0.69	0.12	FALSE
11	GTEx	Pancreas	THBS3	0.36	0.14	lasso	6	0.12	1.0e-05	-2.45	5.5	3.2e-08	-0.34	0.18	0.53	TRUE
12	GTEx	Pancreas	RP11-263K19.4	0.22	0.06	enet	23	0.05	3.1e-03	-2.45	7.6	2.2e-14	-0.43	0.06	0.49	FALSE
13	GTEx	Pituitary	KCNN3	0.41	0.31	lasso	6	0.28	7.4e-08	5.43	5.9	2.9e-09	-0.29	0.88	0.04	TRUE
14	GTEx	Skin Not Sun Exposed Suprapubic	GBAP1	0.15	0.06	lasso	4	0.06	3.6e-04	7.82	-6.0	1.5e-09	0.11	0.54	0.04	FALSE
15	GTEx	Skin Sun Exposed Lower leg	ADAM15	0.14	0.09	lasso	4	0.08	6.1e-07	-12.57	12.4	2.7e-35	-0.96	0.00	1.00	FALSE
16	GTEx	Spleen	SHC1	0.22	0.14	lasso	2	0.08	4.0e-03	5.82	5.2	1.7e-07	-0.15	0.14	0.05	FALSE
17	GTEx	Testis	YY1AP1	0.54	0.34	lasso	7	0.38	4.7e-18	5.78	-5.6	2.5e-08	0.03	1.00	0.00	FALSE
18	GTEx	Testis	MUC1	0.20	0.02	lasso	7	0.07	7.5e-04	7.82	5.1	2.7e-07	-0.11	0.27	0.05	TRUE
19	GTEx	Testis	RP11-29H23.5	0.49	0.34	lasso	5	0.39	2.4e-18	5.78	-5.8	5.2e-09	0.03	1.00	0.00	FALSE
20	GTEx	Thyroid	DCST2	0.16	0.12	lasso	2	0.11	6.4e-09	5.31	-7.2	5.5e-13	0.53	0.38	0.62	FALSE
21	GTEx	Vagina	GBAP1	0.27	0.08	lasso	7	0.17	1.3e-04	5.82	-5.6	2.4e-08	0.09	0.25	0.05	FALSE
22	METSIM	Adipose	DCST2	0.04	0.04	enet	12	0.04	4.3e-07	4.70	-6.1	1.1e-09	0.47	0.86	0.11	FALSE
23	NTR	Blood	ZBTB7B	0.02	0.02	lasso	1	0.01	5.4e-05	-7.06	-7.1	1.6e-12	0.67	0.87	0.03	TRUE
24	ROSMAP	Brain Pre-frontal Cortex	SLC50A1	0.06	0.02	bslmm	331	0.03	4.3e-05	7.61	7.2	4.0e-13	-0.27	0.65	0.04	FALSE
25	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	TRIM46	0.03	0.00	blup	33	0.02	3.6e-03	7.61	6.7	2.4e-11	-0.11	0.03	0.06	FALSE
26	The Cancer Genome Atlas	Breast Invasive Carcinoma	LENEP	0.01	0.00	blup	37	0.01	1.6e-03	4.83	-6.3	3.6e-10	0.48	0.02	0.30	FALSE
27	The Cancer Genome Atlas	Breast Invasive Carcinoma	TRIM46	0.03	0.01	blup	32	0.01	4.9e-03	7.83	6.7	2.4e-11	-0.11	0.01	0.05	TRUE
28	The Cancer Genome Atlas	Breast Invasive Carcinoma	YY1AP1	0.03	0.01	enet	3	0.01	1.6e-03	5.79	-6.7	2.2e-11	-0.02	0.00	0.97	FALSE
29	The Cancer Genome Atlas	Colon Adenocarcinoma	ADAM15	0.15	0.02	blup	49	0.08	1.4e-05	-8.46	6.3	3.0e-10	-0.34	0.03	0.04	TRUE
30	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	MUC1	0.04	0.01	enet	4	0.02	1.3e-03	7.61	7.0	1.8e-12	-0.15	0.03	0.11	FALSE
31	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	RAG1AP1	0.07	0.00	blup	76	0.00	2.9e-01	2.24	5.6	2.2e-08	-0.17	0.02	0.10	TRUE
32	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PBXIP1	0.06	0.06	enet	5	0.06	4.0e-07	5.03	-5.6	2.1e-08	0.21	0.01	0.99	TRUE
33	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	ADAM15	0.09	0.00	blup	49	0.02	3.6e-02	0.74	6.6	3.8e-11	-0.43	0.01	0.09	TRUE
34	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	PBXIP1	0.22	0.14	lasso	4	0.15	8.6e-09	5.23	-5.3	1.1e-07	0.24	0.02	0.98	FALSE
35	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	ZBTB7B	0.05	0.06	lasso	2	0.05	1.8e-06	-12.57	12.6	3.3e-36	-1.00	0.00	1.00	TRUE
36	The Cancer Genome Atlas	Prostate Adenocarcinoma	GBA	0.05	0.01	lasso	2	0.01	2.3e-02	-8.29	7.3	3.4e-13	-0.07	0.00	0.71	FALSE