[Hub]/) : Traits : Impedance of whole body :

chr19:45,286,263-48,406,374

Best TWAS P=5.11e-18 · Best GWAS P=1.99e-37 conditioned to 3.97e-21

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells EBV-transformed lymphocytes SAE1 0.21 0.09 lasso 3 0.07 2.0e-03 6.86 8.7 5.1e-18 0.77 0.06 0.67 TRUE
2 GTEx Nerve Tibial FOSB 0.28 0.00 lasso 4 0.00 4.1e-01 4.69 5.3 1.3e-07 -0.03 0.52 0.47 TRUE
3 GTEx Small Intestine Terminal Ileum PNMAL1 0.40 0.00 enet 11 0.15 2.7e-04 -5.01 -5.7 1.2e-08 -0.01 0.02 0.57 TRUE
4 METSIM Adipose PNMAL1 0.24 0.27 bslmm 380 0.28 2.9e-41 -5.01 -5.2 2.0e-07 -0.01 0.00 0.99 FALSE
5 METSIM Adipose SAE1 0.12 0.04 lasso 5 0.07 1.7e-10 5.86 8.3 1.1e-16 0.61 0.61 0.39 FALSE
6 YFS Blood SAE1 0.07 0.02 enet 18 0.05 3.6e-16 8.50 7.2 5.7e-13 0.56 0.99 0.01 FALSE
7 The Cancer Genome Atlas Breast Invasive Carcinoma TMEM160 0.04 0.00 blup 26 0.01 2.3e-03 0.63 5.5 4.7e-08 0.46 0.00 0.05 FALSE
8 The Cancer Genome Atlas Colon Adenocarcinoma PNMAL1 0.28 0.33 lasso 3 0.35 4.1e-21 -5.01 -5.1 3.1e-07 -0.01 0.00 1.00 FALSE
9 The Cancer Genome Atlas Lung Squamous Cell Carcinoma GRLF1 0.04 0.04 blup 51 0.03 7.0e-05 -4.40 -6.2 4.8e-10 -0.04 0.46 0.03 TRUE
10 The Cancer Genome Atlas Rectum Adenocarcinoma PNMAL1 0.37 0.32 lasso 4 0.21 9.4e-06 -5.01 -5.2 2.7e-07 -0.01 0.00 0.99 FALSE