[Hub]/) : Traits : Impedance of whole body : ← →

chr19:48,931,222-51,224,297

Best TWAS P=2.99e-12 · Best GWAS P=3.09e-11 conditioned to 0.228

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	GTEx	Nerve Tibial	AP2A1	0.16	0.05	lasso	4	0.07	1.3e-05	5.8	7.0	3.0e-12	-0.79	0.07	0.91	TRUE
16	The Cancer Genome Atlas	Colon Adenocarcinoma	SNRNP70	0.05	0.02	lasso	3	0.02	2.9e-02	-5.1	5.8	7.1e-09	-0.07	0.00	0.75	TRUE
5	GTEx	Esophagus Mucosa	AP2A1	0.18	0.09	enet	8	0.13	7.7e-09	5.1	6.7	2.8e-11	-0.77	0.08	0.92	FALSE
10	GTEx	Stomach	VRK3	0.10	-0.01	enet	10	-0.01	7.3e-01	-5.4	-6.5	5.6e-11	0.47	0.04	0.47	FALSE
7	GTEx	Muscle Skeletal	AKT1S1	0.10	0.09	lasso	3	0.08	1.9e-08	6.1	-6.2	7.1e-10	0.81	0.03	0.97	FALSE
20	The Cancer Genome Atlas	Prostate Adenocarcinoma	NUP62	0.05	0.05	blup	54	0.05	9.5e-06	-4.8	5.8	6.0e-09	-0.45	0.28	0.23	FALSE
13	METSIM	Adipose	ATF5	0.12	0.05	blup	341	0.06	1.3e-09	-5.4	5.6	1.8e-08	-0.45	0.81	0.19	FALSE
15	The Cancer Genome Atlas	Breast Invasive Carcinoma	AP2A1	0.04	0.03	lasso	4	0.04	1.8e-08	5.8	-5.6	1.8e-08	0.82	0.05	0.95	FALSE
6	GTEx	Muscle Skeletal	ATF5	0.11	0.09	lasso	4	0.07	8.6e-08	-4.9	5.6	2.1e-08	-0.46	0.49	0.51	FALSE
11	GTEx	Testis	NUP62	0.21	0.09	lasso	6	0.05	4.2e-03	-4.9	5.6	2.8e-08	-0.38	0.31	0.14	FALSE
12	GTEx	Thyroid	FUZ	0.08	0.00	enet	19	0.01	6.5e-02	6.1	-5.5	3.2e-08	0.65	0.05	0.78	FALSE
19	The Cancer Genome Atlas	Lung Adenocarcinoma	PNKP	0.03	0.00	blup	46	0.02	4.0e-03	5.7	5.5	3.2e-08	-0.63	0.01	0.16	FALSE
3	GTEx	Brain Putamen basal ganglia	CTB-33G10.6	0.21	0.02	enet	7	-0.01	4.5e-01	6.1	5.4	5.8e-08	-0.73	0.03	0.36	FALSE
4	GTEx	Cells Transformed fibroblasts	TBC1D17	0.11	0.03	enet	23	0.04	6.5e-04	6.1	-5.4	7.3e-08	0.78	0.02	0.97	FALSE
2	CommonMind	Brain Pre-frontal Cortex	PNKP	0.15	0.16	enet	23	0.16	7.0e-19	5.8	5.4	8.0e-08	-0.78	0.15	0.85	FALSE
18	The Cancer Genome Atlas	Lung Adenocarcinoma	NUP62	0.03	0.03	lasso	3	0.03	2.1e-04	-5.4	5.4	8.3e-08	-0.37	0.27	0.18	FALSE
21	The Cancer Genome Atlas	Testicular Germ Cell Tumors	IL4I1	0.15	-0.01	blup	63	0.05	5.7e-03	-5.4	5.4	8.3e-08	-0.59	0.03	0.22	FALSE
9	GTEx	Spleen	PPFIA3	0.25	0.23	lasso	4	0.21	3.9e-06	-4.4	5.3	1.0e-07	-0.04	0.03	0.90	FALSE
17	The Cancer Genome Atlas	Brain Lower Grade Glioma	TBC1D17	0.06	0.03	blup	50	0.02	9.5e-04	5.7	-5.2	1.8e-07	0.75	0.08	0.88	FALSE
1	CommonMind	Brain Pre-frontal Cortex	MED25	0.05	0.01	blup	361	0.02	2.2e-03	5.6	5.1	2.8e-07	-0.69	0.03	0.88	FALSE
14	YFS	Blood	PNKP	0.22	0.28	enet	47	0.30	3.9e-101	5.7	5.1	2.8e-07	-0.71	0.48	0.52	FALSE