[Hub]/) : Traits : Impedance of whole body :

chr19:48,931,222-51,224,297

Best TWAS P=2.99e-12 · Best GWAS P=3.09e-11 conditioned to 0.228

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex MED25 0.05 0.01 blup 361 0.02 2.2e-03 5.6 5.1 2.8e-07 -0.69 0.03 0.88 FALSE
2 CommonMind Brain Pre-frontal Cortex PNKP 0.15 0.16 enet 23 0.16 7.0e-19 5.8 5.4 8.0e-08 -0.78 0.15 0.85 FALSE
3 GTEx Brain Putamen basal ganglia CTB-33G10.6 0.21 0.02 enet 7 -0.01 4.5e-01 6.1 5.4 5.8e-08 -0.73 0.03 0.36 FALSE
4 GTEx Cells Transformed fibroblasts TBC1D17 0.11 0.03 enet 23 0.04 6.5e-04 6.1 -5.4 7.3e-08 0.78 0.02 0.97 FALSE
5 GTEx Esophagus Mucosa AP2A1 0.18 0.09 enet 8 0.13 7.7e-09 5.1 6.7 2.8e-11 -0.77 0.08 0.92 FALSE
6 GTEx Muscle Skeletal ATF5 0.11 0.09 lasso 4 0.07 8.6e-08 -4.9 5.6 2.1e-08 -0.46 0.49 0.51 FALSE
7 GTEx Muscle Skeletal AKT1S1 0.10 0.09 lasso 3 0.08 1.9e-08 6.1 -6.2 7.1e-10 0.81 0.03 0.97 FALSE
8 GTEx Nerve Tibial AP2A1 0.16 0.05 lasso 4 0.07 1.3e-05 5.8 7.0 3.0e-12 -0.79 0.07 0.91 TRUE
9 GTEx Spleen PPFIA3 0.25 0.23 lasso 4 0.21 3.9e-06 -4.4 5.3 1.0e-07 -0.04 0.03 0.90 FALSE
10 GTEx Stomach VRK3 0.10 -0.01 enet 10 -0.01 7.3e-01 -5.4 -6.5 5.6e-11 0.47 0.04 0.47 FALSE
11 GTEx Testis NUP62 0.21 0.09 lasso 6 0.05 4.2e-03 -4.9 5.6 2.8e-08 -0.38 0.31 0.14 FALSE
12 GTEx Thyroid FUZ 0.08 0.00 enet 19 0.01 6.5e-02 6.1 -5.5 3.2e-08 0.65 0.05 0.78 FALSE
13 METSIM Adipose ATF5 0.12 0.05 blup 341 0.06 1.3e-09 -5.4 5.6 1.8e-08 -0.45 0.81 0.19 FALSE
14 YFS Blood PNKP 0.22 0.28 enet 47 0.30 3.9e-101 5.7 5.1 2.8e-07 -0.71 0.48 0.52 FALSE
15 The Cancer Genome Atlas Breast Invasive Carcinoma AP2A1 0.04 0.03 lasso 4 0.04 1.8e-08 5.8 -5.6 1.8e-08 0.82 0.05 0.95 FALSE
16 The Cancer Genome Atlas Colon Adenocarcinoma SNRNP70 0.05 0.02 lasso 3 0.02 2.9e-02 -5.1 5.8 7.1e-09 -0.07 0.00 0.75 TRUE
17 The Cancer Genome Atlas Brain Lower Grade Glioma TBC1D17 0.06 0.03 blup 50 0.02 9.5e-04 5.7 -5.2 1.8e-07 0.75 0.08 0.88 FALSE
18 The Cancer Genome Atlas Lung Adenocarcinoma NUP62 0.03 0.03 lasso 3 0.03 2.1e-04 -5.4 5.4 8.3e-08 -0.37 0.27 0.18 FALSE
19 The Cancer Genome Atlas Lung Adenocarcinoma PNKP 0.03 0.00 blup 46 0.02 4.0e-03 5.7 5.5 3.2e-08 -0.63 0.01 0.16 FALSE
20 The Cancer Genome Atlas Prostate Adenocarcinoma NUP62 0.05 0.05 blup 54 0.05 9.5e-06 -4.8 5.8 6.0e-09 -0.45 0.28 0.23 FALSE
21 The Cancer Genome Atlas Testicular Germ Cell Tumors IL4I1 0.15 -0.01 blup 63 0.05 5.7e-03 -5.4 5.4 8.3e-08 -0.59 0.03 0.22 FALSE