[Hub]/) : Traits : Impedance of leg (left) :

chr10:75,064,567-79,018,276

Best TWAS P=2.82e-09 · Best GWAS P=1.17e-09 conditioned to 0.00233

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous C10orf11 0.24 0.21 lasso 9 0.20 3.3e-16 -5.4 5.7 9.6e-09 0.06 0.02 0.98 FALSE
2 GTEx Adipose Visceral Omentum C10orf11 0.40 0.32 enet 11 0.27 2.2e-14 -5.4 5.9 3.0e-09 0.06 0.02 0.98 FALSE
3 GTEx Adrenal Gland C10orf11 0.24 0.22 enet 21 0.18 5.8e-07 -5.4 5.5 5.0e-08 0.07 0.02 0.98 FALSE
4 GTEx Artery Aorta VCL 0.17 0.06 lasso 9 0.09 7.9e-06 -3.8 5.6 1.7e-08 -0.57 0.20 0.76 FALSE
5 GTEx Esophagus Muscularis C10orf11 0.45 0.39 enet 42 0.38 5.1e-24 -5.4 5.8 7.7e-09 0.05 0.02 0.98 FALSE
6 GTEx Lung C10orf11 0.30 0.26 lasso 5 0.24 2.0e-18 -5.4 5.7 1.5e-08 0.06 0.02 0.98 FALSE
7 GTEx Testis ZNF503-AS2 0.16 0.02 lasso 4 0.06 1.3e-03 -5.7 -5.3 8.8e-08 -0.07 0.01 0.95 FALSE
8 GTEx Thyroid C10orf11 0.38 0.21 lasso 9 0.25 6.7e-19 -5.0 5.9 2.8e-09 0.08 0.03 0.97 TRUE
9 YFS Blood ADK 0.42 0.38 enet 45 0.44 1.4e-163 -3.9 -5.2 2.1e-07 0.65 0.99 0.00 FALSE
10 YFS Blood AP3M1 0.27 0.11 lasso 5 0.15 1.5e-45 -3.9 -5.4 5.8e-08 0.58 0.99 0.00 FALSE
11 The Cancer Genome Atlas Breast Invasive Carcinoma VCL 0.02 0.00 blup 57 0.01 5.7e-04 -6.1 5.9 4.1e-09 -0.82 0.00 0.91 TRUE
12 The Cancer Genome Atlas Lung Adenocarcinoma VCL 0.04 0.03 lasso 1 0.02 5.8e-04 -5.7 5.7 1.0e-08 -0.94 0.01 0.93 FALSE
13 The Cancer Genome Atlas Prostate Adenocarcinoma VCL 0.08 0.06 blup 56 0.07 1.5e-07 -6.1 5.9 4.8e-09 -0.93 0.00 1.00 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma VCL 0.08 0.02 blup 57 0.05 7.6e-06 -3.9 5.8 5.5e-09 -0.71 0.10 0.78 FALSE