[Hub]/) : Traits : Impedance of leg (left) : ← →

chr1:149,672,809-152,126,467

Best TWAS P=1.03e-11 · Best GWAS P=2.62e-09 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	CTSS	0.04	0.01	bslmm	313	0.02	5.5e-04	5.7	-6.8	1.0e-11	0.21	0.02	0.97	TRUE
21	The Cancer Genome Atlas	Brain Lower Grade Glioma	SV2A	0.04	0.00	blup	9	0.03	5.5e-04	-5.4	-6.1	8.2e-10	0.08	0.00	0.65	TRUE
15	YFS	Blood	SCNM1	0.09	0.04	enet	62	0.08	1.3e-24	-3.4	6.0	1.5e-09	-0.27	1.00	0.00	TRUE
17	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C1orf54	0.04	0.04	lasso	2	0.03	2.0e-04	-6.0	6.0	1.6e-09	-0.99	0.01	0.95	TRUE
22	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	MRPS21	0.04	0.03	blup	15	0.04	4.0e-05	2.8	-5.8	5.9e-09	0.87	0.03	0.69	TRUE
8	GTEx	Muscle Skeletal	CTSS	0.04	0.01	enet	13	0.03	1.4e-03	-5.2	-5.8	7.7e-09	0.12	0.44	0.15	TRUE
19	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PSMB4	0.03	0.00	blup	37	0.02	7.0e-03	-4.4	5.7	9.6e-09	-0.05	0.01	0.54	TRUE
5	GTEx	Brain Hippocampus	ARNT	0.14	0.09	enet	14	0.08	5.3e-03	-4.1	-5.7	1.6e-08	0.33	0.10	0.09	TRUE
25	The Cancer Genome Atlas	Prostate Adenocarcinoma	SF3B4	0.03	0.02	blup	10	0.01	1.4e-02	-4.5	-5.6	2.3e-08	-0.01	0.02	0.45	TRUE
10	GTEx	Skin Sun Exposed Lower leg	SEMA6C	0.10	0.07	lasso	5	0.04	2.6e-04	5.8	5.5	3.9e-08	-0.16	0.01	0.99	TRUE
23	The Cancer Genome Atlas	Prostate Adenocarcinoma	C1orf54	0.09	0.00	blup	17	0.03	7.4e-04	4.6	6.4	1.6e-10	-0.68	0.02	0.45	FALSE
4	GTEx	Artery Aorta	RPRD2	0.08	-0.01	enet	19	0.00	4.2e-01	-4.7	6.4	2.1e-10	-0.50	0.09	0.20	FALSE
16	The Cancer Genome Atlas	Breast Invasive Carcinoma	C1orf54	0.06	0.02	enet	13	0.02	1.2e-05	-6.0	6.0	1.9e-09	-0.76	0.01	0.92	FALSE
18	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C1orf54	0.06	0.03	lasso	1	0.03	1.3e-04	-6.0	6.0	2.6e-09	-1.00	0.01	0.77	FALSE
24	The Cancer Genome Atlas	Prostate Adenocarcinoma	ENSA	0.02	0.01	enet	3	0.01	2.5e-02	-4.9	5.9	3.5e-09	-0.39	0.00	0.67	FALSE
3	GTEx	Adipose Subcutaneous	SEMA6C	0.12	0.11	lasso	2	0.11	1.8e-09	5.7	5.7	9.7e-09	-0.17	0.02	0.98	FALSE
6	GTEx	Breast Mammary Tissue (Male)	RP11-54A4.2	0.07	0.01	enet	2	0.03	7.4e-02	5.4	5.5	4.5e-08	-0.11	0.04	0.08	FALSE
14	METSIM	Adipose	TMOD4	0.02	0.00	blup	312	0.01	3.2e-02	-5.2	5.4	5.7e-08	-0.12	0.08	0.03	FALSE
13	METSIM	Adipose	TARS2	0.09	0.09	enet	8	0.08	1.6e-12	-5.0	5.4	5.8e-08	-0.96	0.02	0.98	FALSE
9	GTEx	Skin Not Sun Exposed Suprapubic	SEMA6C	0.13	0.10	lasso	4	0.07	7.4e-05	5.8	5.4	6.1e-08	-0.13	0.01	0.99	FALSE
2	GTEx	Adipose Subcutaneous	TARS2	0.06	0.02	enet	8	0.03	2.2e-03	-4.3	5.4	6.5e-08	-0.92	0.02	0.98	FALSE
20	The Cancer Genome Atlas	Brain Lower Grade Glioma	MRPS21	0.13	0.13	enet	10	0.13	1.7e-14	2.8	-5.2	2.4e-07	0.84	0.31	0.69	FALSE
12	METSIM	Adipose	POGZ	0.06	0.05	lasso	12	0.03	9.3e-06	-4.4	-5.2	2.6e-07	0.04	0.94	0.05	FALSE
11	GTEx	Testis	RPRD2	0.33	0.13	lasso	7	0.19	9.1e-09	-4.3	5.1	2.9e-07	-0.70	0.28	0.70	FALSE
26	The Cancer Genome Atlas	Thyroid Carcinoma	SELENBP1	0.06	0.02	enet	7	0.05	2.3e-05	-4.4	-5.1	3.0e-07	0.07	0.00	0.93	FALSE
7	GTEx	Esophagus Muscularis	BOLA1	0.07	0.00	lasso	4	0.00	2.5e-01	-3.0	5.1	3.1e-07	0.03	0.03	0.07	FALSE