Hub : Genes

PSMB4

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0880 0.0290 1.5e-05 0.069 0.043 0.048 0.046 0.062 8.7e-09 5.2e-06 1.4e-06 2.4e-06 4.8e-08
2 GTEx Adipose Subcutaneous 0.0630 0.0270 4.0e-03 0.042 NA 0.039 NA 0.035 2.3e-04 NA 3.4e-04 NA 7.4e-04
3 GTEx Artery Coronary 0.1690 0.0720 5.8e-03 0.094 NA 0.070 NA 0.067 4.7e-04 NA 2.3e-03 NA 2.8e-03
4 GTEx Cells Transformed fibroblasts 0.1370 0.0440 4.9e-05 0.059 NA 0.026 NA 0.035 3.4e-05 NA 4.7e-03 NA 1.2e-03
5 GTEx Vagina 0.2500 0.1010 5.5e-03 -0.013 NA 0.000 NA -0.013 9.0e-01 NA 3.2e-01 NA 9.2e-01
6 METSIM Adipose 0.0322 0.0158 6.1e-03 0.021 0.008 0.006 0.006 0.006 3.0e-04 1.8e-02 3.7e-02 3.5e-02 3.4e-02
7 YFS Blood 0.0197 0.0075 8.2e-05 0.010 0.013 0.022 0.016 0.021 1.7e-04 3.2e-05 7.0e-08 3.9e-06 1.4e-07
8 TCGA Kidney Renal Clear Cell Carcinoma 0.0271 0.0165 2.0e-03 0.000 0.015 0.010 NA 0.003 2.8e-01 7.0e-03 2.2e-02 NA 1.5e-01

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 5.3 8.3 14.2 -3.1 2.7 3.3 3.4 3.8 -1.3 -1.9 2.7
Bipolar Disorder or Schizophrenia 4.7 11.4 15.4 -3.9 3.5 3.6 3.9 3.2 -2.0 -3.1 3.4
Depressed Affect (Nagel 2018) 1.3 2.7 4.9 2.2 -1.9 -1.6 -2.1 -1.3 0.3 0.7 -2.0
Depression (Nagel 2018) 0.7 1.1 1.8 0.9 -1.1 -1.3 -1.2 -0.8 -1.3 -0.9 -0.6
Intelligence (Savage-Jansen 2018) 0.3 0.8 1.9 -0.8 0.6 1.2 0.7 1.4 -0.9 -0.0 1.0
Neuroticism (Nagel 2018) 0.1 0.3 1.2 0.4 -0.6 -0.7 -0.5 -0.2 -0.0 1.1 0.1
Schizophrenia (2018) 1.9 3.9 6.3 -2.5 2.2 1.9 2.3 1.2 -1.2 -1.7 2.2
Schizophrenia vs Biploar Disorder 0.2 0.3 0.7 -0.3 0.9 -0.0 -0.1 -0.6 0.4 0.8 0.6
Worry (Nagel 2018) 1.2 2.6 4.9 -2.2 1.4 1.0 2.0 1.7 -0.8 0.2 2.2
Alzheimer’s Disease (in mother) 0.8 1.0 1.9 0.7 -1.0 -1.1 -0.8 1.4 -0.8 1.2 -0.6
Alzheimer’s Disease (in father) 1.0 1.1 3.0 -1.4 1.1 0.4 1.3 -0.0 0.1 -1.0 1.7
Alzheimer’s Disease (including proxy) 0.1 0.2 0.4 -0.4 -0.1 -0.6 0.2 0.5 0.2 0.6 0.3
Crohns Disease (2017) 1.3 2.8 13.8 0.9 -0.2 -0.6 -1.8 -3.7 0.9 1.8 0.2
Irritable Bowel Disease (IBD) 0.4 0.8 2.9 -0.2 0.6 0.1 -0.9 -1.7 -0.5 0.8 1.3
Ulcerative Colitis (UC) 0.3 0.5 1.9 -0.4 0.4 0.3 -0.6 0.7 -1.4 -0.6 0.8
Major Depression (MDD) 1.3 1.6 2.9 -1.6 1.2 1.3 1.7 1.5 0.1 0.5 1.4
Reaction Time 0.3 0.7 1.9 1.0 -1.1 -0.4 -0.9 -1.4 -0.4 -0.1 -0.3
Verbal and Numeric Reasoning (VNR) 0.3 0.6 2.2 0.8 -0.6 0.2 -0.9 -0.1 -1.5 -0.9 -0.2
Breast Cancer 0.1 0.4 1.0 -0.1 -0.1 0.9 0.1 0.4 -0.3 -1.0 -0.8
Ovarian Cancer 0.5 0.7 4.0 0.4 -0.3 -0.3 -0.3 -2.0 -0.7 -0.8 -0.5
Prostate Cancer 1.4 2.0 4.4 1.3 -1.2 -0.3 -1.3 1.9 1.6 0.4 -2.1
Age at First Birth 1.0 1.5 4.4 0.6 -0.2 -0.5 -0.5 2.1 -1.9 -1.7 -0.4
Bipolar Disorder (2011) 4.0 3.8 7.4 -2.1 2.0 2.0 2.6 2.7 0.4 -0.9 1.7
Body Mass Index (BMI) (2010) 0.6 0.8 3.9 0.2 -0.1 -0.7 -0.2 -1.2 -2.0 -0.4 -0.6
Coronary Artery Disease (CAD) 2.9 3.4 10.0 1.6 -1.9 -1.6 -2.3 -3.2 -0.2 1.2 -1.5
Crohns Disease (2012) 0.5 0.8 3.0 0.1 0.3 0.1 -0.5 -1.7 0.8 1.2 0.9
Mean Putamen Volume 0.4 0.5 1.4 -0.5 0.6 -0.1 0.6 -1.0 -1.2 -0.3 0.7
Fasting Glucose 1.0 1.2 2.1 -1.3 1.5 1.3 1.4 -0.1 0.7 0.1 1.4
HbA1C 0.5 0.6 1.1 0.7 -0.9 -1.1 -0.7 -0.8 0.9 -0.1 -0.7
HDL Cholesterol 1.0 1.7 2.7 1.6 -1.1 -1.1 -1.6 1.0 -1.5 -0.7 -1.7
LDL Cholesterol 0.6 1.0 2.3 -1.5 0.7 0.9 1.4 -0.9 0.6 0.3 1.0
Lupus 1.2 1.8 3.3 -1.7 1.8 1.8 1.5 0.3 -1.2 -0.6 0.8
Neuroticism (2016) 0.6 0.9 2.2 -1.0 0.2 -0.3 0.7 1.5 -1.1 0.5 1.5
Primary Biliary Cirrhosis 0.7 1.1 3.1 1.0 -0.6 -0.0 -0.8 0.6 -1.4 -1.0 -1.8
Rheumatoid Arthritis 0.9 1.2 3.1 0.9 -1.5 -1.8 -1.0 0.2 1.1 0.8 -0.6
Schizophrenia (2014) 3.2 7.0 10.8 -3.3 2.9 2.7 3.1 2.7 -1.2 -1.9 2.7
Triglycerides 0.2 0.3 0.9 -0.3 -0.1 -0.1 0.3 -1.0 -0.4 -0.9 -0.0
Type 2 Diabetes (T2D) (2012) 1.4 1.6 7.9 0.9 -1.0 -0.7 -1.0 -2.8 0.2 -0.4 -1.2
Ulcerative Colitis 0.8 1.2 2.7 -1.3 1.1 0.8 0.7 1.0 -1.4 -0.2 1.6
Blood Eosinophil Count 0.2 1.2 3.5 -0.4 0.5 1.5 0.1 0.6 1.9 0.1 -1.7
Blood Platelet Count 0.8 9.4 27.1 3.6 -4.1 -0.8 -3.3 0.3 2.5 0.6 -5.2
Blood Red Count 0.7 6.5 24.0 -2.5 1.7 1.1 2.3 4.9 -1.6 -0.3 3.0
Blood White Count 0.1 1.0 2.4 0.4 -1.5 -1.4 -0.6 0.3 0.5 0.9 -1.6
Heel T-Score 0.1 0.5 1.5 0.1 0.2 0.6 -0.6 -0.9 0.9 -1.2 0.4
BMI 2.0 11.5 23.1 3.4 -3.1 -4.2 -3.5 -4.8 -0.7 1.0 -4.0
Height 1.3 25.8 78.9 -3.6 4.9 3.2 4.3 8.9 4.7 3.4 5.3
Waist Hip Ratio (WHR) 0.8 3.7 8.2 -2.6 1.5 2.9 2.2 -1.1 0.3 0.1 2.5
Systolic Blood Pressure 0.2 0.9 4.1 -0.2 0.1 -0.9 0.4 -2.0 -1.3 0.4 0.4
Smoking Status 0.4 0.9 2.4 -0.8 0.7 0.2 0.7 -1.2 1.6 0.6 1.0
Allergy or Eczema 2.8 7.3 14.4 -3.3 3.8 2.9 2.2 1.9 0.7 1.2 3.8
Cardiovascular Disease 1.0 3.2 7.7 -2.8 2.2 0.8 2.5 0.3 -0.5 0.3 2.4
Hypothyroidism (self reported) 4.0 9.2 16.9 -3.9 3.3 2.5 3.2 2.2 -1.6 -2.6 4.1
Respiratory disease 3.8 8.4 15.6 -2.8 3.3 2.3 2.2 2.2 3.9 2.8 3.2
Type 2 Diabetes (T2D) (2018) 0.6 1.2 7.9 0.1 -0.7 -0.6 -0.1 -2.8 -0.6 0.2 0.3
Lung FEV1/FVC ratio 0.2 0.9 3.6 -0.5 -0.6 -1.1 0.4 -1.9 -0.5 0.5 0.7
Lung FVC 1.1 5.6 13.8 -2.2 2.8 2.9 2.7 3.7 0.8 -1.1 1.0
Neuroticism 0.1 0.2 0.4 0.0 -0.6 -0.6 -0.0 -0.0 -0.6 0.2 0.2
Chronotype (morning person) 0.1 0.3 0.7 0.1 -0.4 -0.6 -0.1 -0.8 -0.8 0.6 0.3
Hair Pigment 0.0 1.3 5.2 -0.7 1.2 0.1 0.9 -2.3 1.4 0.3 -0.3
Tanning 0.2 2.4 9.0 1.3 -0.8 0.3 -1.6 1.6 3.0 -0.3 -1.8
Hand grip strength (left) 0.6 1.6 7.7 -0.4 1.7 0.7 0.6 0.5 2.8 0.8 -0.3
Number of treatments/medications taken 0.4 0.8 2.4 -0.7 0.3 -0.2 0.5 0.7 1.1 1.6 1.0
Average weekly spirits intake 1.3 1.6 3.5 1.1 -0.8 -1.0 -1.5 -0.5 1.6 1.9 -1.4
Sensitivity / hurt feelings 0.7 1.2 6.1 0.6 -0.6 -1.0 -0.5 -1.0 0.7 2.5 0.3
Frequency of depressed mood in last 2 weeks 0.1 0.2 0.7 -0.1 0.1 -0.5 0.1 -0.5 -0.8 0.1 0.3
Hearing difficulty/problems: Yes 0.8 1.2 3.2 -0.8 1.2 1.4 0.5 1.2 1.8 0.5 0.7
Relative age of first facial hair 4.0 8.3 13.7 -3.0 3.4 3.4 2.9 3.7 0.9 1.1 3.2
Other serious medical condition/disability diagnosed by doctor 4.1 5.3 8.4 -2.7 2.2 2.6 2.5 2.9 1.0 0.2 2.8
Ever used hormone-replacement therapy (HRT) 1.0 1.2 3.0 -1.0 0.9 0.5 0.7 0.9 1.2 1.7 1.4
Ever had hysterectomy (womb removed) 0.5 0.6 2.6 0.3 -0.5 -1.0 -0.3 1.6 0.2 0.9 -0.0
Systolic blood pressure, automated reading 0.4 1.0 3.2 0.4 -0.0 -1.0 -0.2 -1.8 -1.4 -1.3 -0.5
Eye problems/disorders: Diabetes related eye disease 1.5 1.7 6.3 1.1 -0.9 -0.9 -1.7 -2.5 -0.5 0.5 -1.0
Angina 1.9 2.4 6.8 -1.4 1.2 0.8 1.4 -0.2 1.0 2.6 2.3
Medication for hormone replacement therapy 0.6 0.6 2.0 -0.7 1.0 1.4 0.7 -0.1 0.8 -0.4 0.3
Vitamin and mineral supplements 0.2 0.3 1.4 0.3 0.3 0.6 -0.1 -0.4 0.4 0.2 -1.2
Supplements: Zinc 0.8 0.9 2.6 0.1 -0.0 -0.8 -0.1 -1.3 1.3 1.6 0.6
Medication: Co-codamol 0.6 0.7 1.8 0.5 -0.7 0.1 -0.2 -1.2 -0.1 1.2 -1.4
Medication: Metformin 0.8 1.2 5.8 -0.6 -0.1 -0.4 0.5 -2.4 0.3 1.4 1.0
Diabetes (father) 0.1 0.2 0.4 -0.4 0.1 0.6 0.2 -0.6 -0.5 0.0 0.5
Diabetes (mother) 0.6 0.8 4.5 -0.6 0.5 0.7 0.5 -2.1 0.6 0.3 0.4
Severe depression (siblings) 0.6 0.7 1.7 -0.6 0.3 0.5 0.3 1.0 -1.3 -0.9 1.2
Pack years adult smoking proportion 0.1 0.1 0.5 -0.1 -0.2 -0.6 0.1 -0.1 -0.0 0.7 0.1
Impedance of leg (right) 3.0 14.4 36.7 -4.7 3.7 3.6 4.8 2.0 -1.4 0.9 6.1
Leg fat-free mass (left) 0.9 4.7 9.1 2.5 -1.5 -3.0 -2.2 -0.3 2.1 1.9 -2.7
Trunk fat percentage 0.4 1.6 8.5 -0.1 0.4 -1.2 0.0 -1.0 0.8 2.9 1.0
Hand grip strength (right) 0.3 0.8 3.1 0.4 1.1 -0.1 -0.1 -0.4 1.8 1.0 -1.0
Townsend deprivation index at recruitment 1.8 2.5 6.9 -0.9 0.5 1.0 0.6 -2.0 2.6 2.2 1.2
Current tobacco smoking 0.9 1.5 4.5 0.3 0.1 0.0 -0.6 -1.8 2.1 2.0 0.1
Average weekly fortified wine intake 1.2 1.3 3.1 1.6 -1.3 -1.8 -1.6 -0.4 0.3 -0.0 -0.9
Maternal smoking around birth 1.5 2.1 8.4 0.6 -0.7 -0.9 -0.7 -1.8 1.7 2.9 -0.4
Fed-up feelings 0.4 0.7 1.5 -0.7 1.0 1.1 0.8 0.5 0.9 1.2 0.5
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.4 2.6 0.2 -0.1 -0.3 -0.6 -1.6 0.2 0.4 -0.1
Relative age voice broke 3.5 5.4 8.5 -2.8 2.9 2.9 2.7 2.4 0.8 0.3 2.1
Taking other prescription medications 2.4 3.8 6.3 -2.5 2.1 1.6 2.3 2.1 0.5 0.6 2.5
Age when periods started (menarche) 3.0 7.3 22.6 -2.3 2.8 3.2 2.1 4.8 2.2 0.8 1.7
Bilateral oophorectomy (both ovaries removed) 0.7 0.8 3.0 0.3 0.3 -0.1 -0.3 1.7 1.1 1.1 0.6
Heel bone mineral density (BMD) T-score, automated (left) 0.4 0.8 3.0 0.1 0.2 0.6 -0.4 -1.6 -0.7 -1.7 0.2
Tinnitus: Yes, but not now, but have in the past 0.5 0.5 1.1 -0.6 0.5 0.3 0.7 0.9 -0.5 1.1 0.7
Qualifications: CSEs or equivalent 1.0 1.4 6.7 0.5 -0.0 -0.2 -0.7 -1.6 1.0 2.6 0.2
Serious illness, injury or assault to yourself 0.3 0.3 0.9 -0.6 0.4 -0.6 0.3 -0.9 -0.6 -0.2 0.6
High blood pressure 0.5 1.4 3.1 -1.8 1.5 -0.1 1.6 -0.6 -0.0 0.9 1.6
Hayfever, allergic rhinitis or eczema 1.3 2.9 6.2 -1.9 2.5 2.1 1.1 1.3 -0.5 0.6 2.4
Multivitamins +/- minerals 0.1 0.1 0.2 0.1 -0.5 -0.4 -0.4 0.5 -0.1 0.1 0.4
Stomach or abdominal pain in last month 1.2 1.4 3.0 1.4 -1.2 -0.9 -1.4 -0.7 -1.3 -0.4 -1.7
Supplements: Glucosamine 0.1 0.2 0.5 0.1 0.7 0.6 -0.2 0.1 0.4 0.0 -0.6
Diverticular disease/diverticulitis (self-reported) 0.3 0.3 1.8 -0.4 0.4 0.1 0.2 0.5 -0.4 -1.4 -0.1
Medication: Atenolol 0.1 0.2 1.0 -0.0 -0.2 0.3 -0.1 -0.1 -0.3 1.0 0.1
Medication: Levothyroxine sodium 2.7 4.6 9.5 -2.8 1.8 1.8 2.5 2.2 -0.7 -1.2 3.1
Sitting height 1.0 7.4 17.9 -1.8 3.2 2.7 2.2 4.2 2.7 2.1 1.9
Chronic bronchitis/emphysema (father) 1.9 2.2 4.7 1.9 -1.9 -0.9 -2.2 0.7 1.3 1.1 -1.4
High blood pressure (mother) 2.0 2.7 5.5 -1.9 1.6 1.4 2.0 -2.3 -1.0 -0.8 1.8
Body mass index (BMI) 2.3 10.0 16.9 3.5 -2.9 -3.9 -3.6 -3.6 -0.1 0.8 -4.1
Impedance of leg (left) 2.7 13.0 32.9 -4.4 3.4 3.7 4.4 2.2 -1.0 1.1 5.7
Leg predicted mass (left) 0.9 4.8 9.3 2.5 -1.5 -3.0 -2.3 -0.3 2.1 2.0 -2.7
Trunk fat mass 0.4 1.5 7.8 0.5 0.0 -1.7 -0.5 -0.7 0.9 2.8 0.1
Waist circumference 0.9 3.2 5.0 1.8 -1.7 -2.2 -1.9 -1.9 0.5 1.4 -2.2
Number of incorrect matches in round 0.2 0.3 1.1 0.4 -0.2 0.0 -0.3 -0.3 -0.5 -1.0 -0.8
Past tobacco smoking 1.6 2.9 5.0 2.2 -1.6 -1.1 -2.2 -0.3 1.1 2.0 -2.0
Alcohol usually taken with meals 2.1 3.3 10.7 0.8 -0.8 0.4 -0.6 3.3 -1.8 -3.1 -1.1
Nervous feelings 2.6 4.8 8.3 -2.8 2.0 2.1 2.8 1.8 -1.3 -1.2 2.9
Frequency of tenseness / restlessness in last 2 weeks 2.9 4.5 7.7 -2.6 2.6 2.4 2.8 1.8 1.1 0.4 2.2
Hearing difficulty/problems with background noise 0.8 1.3 2.2 -1.3 1.5 1.5 1.2 1.4 0.2 -0.4 0.8
Hair/balding pattern: Pattern 2 0.3 0.4 1.4 0.4 -0.2 -0.6 -0.4 -1.1 0.1 1.2 -0.1
Had menopause 1.1 1.4 3.2 -1.1 0.9 0.2 0.8 1.4 -0.6 -1.8 1.7
Had other major operations 0.4 0.4 1.5 0.2 -0.5 -1.0 0.4 1.2 0.2 -0.4 -0.5
Forced vital capacity (FVC) 2.8 10.6 28.0 -3.0 3.9 3.5 3.6 5.3 1.4 0.3 2.4
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.5 2.1 0.2 0.1 0.5 -0.6 -1.4 0.0 -1.3 -0.2
Ever unenthusiastic/disinterested for a whole week 1.0 1.2 4.8 -0.8 0.4 0.8 0.8 2.2 -1.4 -0.9 0.2
Qualifications: None of the above 0.8 1.7 3.6 0.9 -1.2 -1.2 -1.2 -0.9 1.9 1.8 -0.9
Financial difficulties in last 2 years 1.1 1.5 3.4 -1.9 1.4 0.9 1.6 -0.5 0.1 -0.3 1.7
Mouth/teeth dental problems 0.5 0.7 2.0 1.0 -0.9 -0.6 -1.4 -0.1 -0.3 -0.2 -1.1
Heart attack 3.0 3.8 9.9 -2.7 2.0 1.4 2.6 -0.1 -0.4 0.6 3.1
Allergy 2.5 5.7 12.8 3.0 -3.1 -2.2 -2.0 -2.2 -0.6 -0.5 -3.6
Pain all over the body in last month 0.3 0.4 1.2 -0.4 -0.0 -0.3 0.5 0.9 -1.1 0.1 0.6
Diabetes (self-reported) 1.4 2.1 12.2 -0.5 -0.4 -1.3 0.3 -3.5 -0.7 0.6 1.2
Hayfever/allergic rhinitis (self-reported) 0.1 0.1 0.6 -0.0 -0.1 0.4 -0.4 0.1 -0.8 -0.3 -0.4
Medication: Ramipril 1.4 1.8 6.4 -0.9 0.2 -0.8 0.7 -1.6 1.4 2.5 1.2
Medication: Simvastatin 0.6 0.8 2.6 -1.2 0.5 -0.4 1.0 -1.6 0.4 -0.0 1.0
Fluid intelligence score 0.7 1.5 5.2 -0.9 1.2 2.3 1.0 1.0 -1.4 -0.4 0.8
Illnesses of siblings 1.0 1.4 2.7 1.5 -1.6 -1.6 -1.2 0.1 0.1 0.5 -1.4
Neuroticism score 0.6 1.3 3.0 -1.3 0.9 0.9 1.3 1.0 0.3 1.3 1.7
Weight 0.7 3.5 7.7 2.1 -1.2 -2.8 -1.8 -0.8 1.2 2.0 -2.2
Impedance of arm (right) 4.9 22.9 58.1 -5.4 4.9 4.7 5.3 4.2 0.9 2.0 7.6
Arm fat percentage (right) 0.4 1.6 4.0 0.8 -0.4 -1.8 -0.9 -1.7 0.5 2.0 -0.3
Trunk fat-free mass 0.6 3.6 7.8 2.3 -1.4 -2.8 -1.9 0.3 1.3 0.8 -2.8
Hip circumference 1.7 7.3 14.6 3.4 -2.5 -3.8 -3.2 -1.2 0.3 1.5 -3.4
Time employed in main current job 0.3 0.3 0.7 -0.3 0.5 0.8 0.4 0.8 0.7 0.0 -0.4
Alcohol intake versus 10 years previously 0.7 1.0 3.0 0.1 0.4 -0.1 -0.2 -1.7 1.7 1.4 0.2
Father’s age at death 0.9 1.2 2.2 -1.2 0.6 0.3 1.2 1.4 -0.4 -1.5 1.2
Worrier / anxious feelings 4.6 8.7 15.1 -3.7 3.0 2.9 3.7 3.1 -0.9 -0.3 3.9
Frequency of tiredness / lethargy in last 2 weeks 0.6 1.0 2.8 0.4 -0.3 -0.4 -0.7 1.7 1.1 1.6 -0.5
Falls in the last year 1.4 1.9 4.6 -1.4 1.5 1.2 1.2 2.1 -0.2 -0.5 1.7
Hair/balding pattern: Pattern 3 1.7 2.5 4.6 2.0 -1.9 -1.0 -2.1 -1.6 0.0 -0.2 -2.1
Number of live births 0.3 0.5 2.5 0.3 -0.4 0.0 -0.3 0.2 -1.0 -1.6 -0.1
Forced expiratory volume in 1-second (FEV1) 2.3 7.7 19.6 -2.8 3.3 2.8 3.3 4.4 0.7 -0.0 2.2
Pulse rate 1.9 3.2 6.4 -2.1 2.5 2.2 1.8 1.6 0.7 -1.2 1.4
Happiness 1.0 1.3 4.8 -0.4 0.4 0.5 0.4 2.2 0.9 1.9 0.5
Noisy workplace 1.8 2.2 12.0 0.7 -0.4 -0.7 -0.7 -3.5 1.0 1.4 -1.3
Qualifications: A levels/AS levels or equivalent 0.2 0.5 1.3 0.1 -0.1 0.9 -0.0 1.1 -0.3 -1.1 0.5
Serious illness, injury or assault of a close relative in last 2 years 0.2 0.2 0.9 -0.2 -0.1 -0.7 0.3 -1.0 -0.0 0.5 0.3
Mouth/teeth dental problems: Dentures 0.4 0.6 1.3 1.1 -0.6 -0.5 -0.7 -1.0 -0.6 -0.6 -1.0
Asthma 2.1 4.2 8.4 -2.0 2.3 1.3 1.5 1.0 2.9 2.4 2.4
Medication: Ibuprofen (e.g. Nurofen) 0.9 1.2 4.6 1.2 -1.2 -2.1 -1.3 -0.3 -0.2 -0.5 -0.5
Medication: Cholesterol lowering 1.9 2.9 5.3 -2.1 1.7 1.0 2.0 -1.3 0.9 1.6 2.3
Depression (self-reported) 0.3 0.4 1.8 -0.1 0.1 0.6 0.0 1.3 0.5 -0.6 0.1
Medication: Lansoprazole 0.3 0.3 0.9 -0.7 0.9 0.5 0.7 -0.2 0.2 -0.3 0.4
Prospective memory result 5.5 6.8 13.0 3.2 -3.6 -2.6 -3.2 -1.8 -0.1 0.8 -3.1
Lung cancer (father) 0.1 0.1 0.3 0.0 -0.0 0.1 -0.0 -0.6 -0.2 0.5 -0.1
Illnesses of mother 1.0 1.2 1.7 1.3 -0.8 -0.8 -1.0 1.2 1.2 1.0 -1.2
Forced expiratory volume in 1-second (FEV1), Best measure 1.8 5.7 20.1 -2.1 2.7 2.2 2.5 4.5 0.2 -0.4 1.6
Pulse wave Arterial Stiffness index 0.3 0.3 0.8 -0.8 0.5 0.7 0.5 -0.0 0.9 -0.2 0.5
Impedance of arm (left) 3.7 16.9 44.6 -4.7 4.0 3.9 4.6 3.6 0.8 1.8 6.7
Arm fat mass (right) 0.8 3.2 7.1 1.9 -1.2 -2.7 -1.9 -1.7 0.7 1.9 -1.8
Trunk predicted mass 0.6 3.7 7.9 2.3 -1.4 -2.8 -1.9 0.3 1.3 0.8 -2.8
Standing height 1.3 12.7 36.1 -2.8 3.6 2.2 3.5 6.0 2.8 2.6 3.8
Length of working week for main job 2.8 3.1 12.5 1.3 -1.7 -1.5 -1.2 -3.5 1.0 1.2 -1.3
Exposure to tobacco smoke at home 0.2 0.3 1.4 0.0 -0.0 0.1 -0.2 -0.1 1.2 0.7 0.1
Breastfed as a baby 1.4 1.8 6.6 0.3 -0.5 -0.3 -0.2 2.6 -1.8 -1.9 -0.4
Tense / ‘highly strung’ 1.2 2.0 3.3 -1.8 1.3 1.3 1.8 1.7 0.1 0.5 1.6
Seen doctor (GP) for nerves, anxiety, tension or depression 6.8 10.4 18.4 -4.0 3.4 2.8 3.9 3.9 -0.7 -0.2 4.3
Hair/balding pattern: Pattern 4 1.4 3.3 6.0 -1.9 2.1 1.2 2.0 0.1 -2.1 -2.4 1.7
Birth weight of first child 0.7 1.2 2.2 -1.4 1.5 1.1 1.3 0.8 -0.4 -0.5 1.2
Peak expiratory flow (PEF) 1.7 3.9 12.0 -2.1 1.7 2.0 2.2 3.5 0.2 -0.8 1.4
Pulse wave reflection index 0.5 0.6 1.3 -1.0 0.7 0.4 1.2 0.1 -0.5 -0.7 1.2
Ever highly irritable/argumentative for 2 days 0.3 0.4 0.8 0.6 -0.4 -0.9 -0.5 -0.3 -0.8 0.8 -0.2
Loud music exposure frequency 1.1 1.2 5.4 -0.2 0.4 0.1 0.0 1.9 -2.3 -0.2 0.7
Qualifications: O levels/GCSEs or equivalent 0.1 0.2 0.3 0.5 -0.5 -0.1 -0.6 -0.5 -0.4 -0.3 0.3
Mouth/teeth dental problems: Bleeding gums 5.7 7.4 13.9 -3.5 3.3 2.3 3.7 1.9 -0.7 0.1 3.5
Blood clot in the leg (DVT) 0.9 1.2 3.0 -1.2 0.1 -0.2 1.1 1.7 0.0 -1.0 1.6
Medication: Paracetamol 1.0 1.6 4.5 -1.4 0.8 -0.1 1.4 0.4 1.5 2.1 1.1
Headache pain in last month 1.7 2.9 5.9 -2.0 2.4 1.9 2.2 1.6 -0.1 0.1 1.3
Medication for cholesterol, blood pressure or diabetes 1.2 2.0 4.2 2.0 -1.5 -0.5 -1.9 0.3 -0.1 -1.4 -2.0
Glaucoma (self-reported) 0.7 0.8 2.5 0.4 -0.1 -1.3 -0.7 -1.6 -1.1 0.2 0.4
Gout (self-reported) 0.8 1.2 2.1 -1.0 1.4 0.9 0.8 -1.4 1.5 0.7 0.6
Hypothyroidism/myxoedema (self-reported) 3.4 6.7 12.0 -3.2 2.5 2.7 2.7 2.3 -1.4 -2.0 3.5
Medication: Amlodipine 0.2 0.2 0.8 -0.2 0.1 -0.7 0.0 -0.2 -0.9 0.5 0.2
Medication: Ventolin 100micrograms inhaler 1.4 1.8 4.4 -1.2 1.9 1.5 0.9 0.3 2.1 1.1 0.8
Birth weight 0.8 1.7 4.7 -0.7 1.2 2.2 1.0 1.2 1.5 1.4 -0.2
Chronic bronchitis/emphysema (mother) 0.3 0.3 0.7 0.8 -0.8 -0.6 -0.8 -0.2 0.3 0.5 -0.4
High blood pressure (siblings) 1.4 2.0 4.2 -1.8 2.1 2.1 1.8 0.4 0.1 -0.2 1.0
Forced vital capacity (FVC), Best measure 2.4 8.7 28.4 -2.5 3.5 2.9 3.0 5.3 1.4 0.1 1.8
Body fat percentage 0.4 1.6 7.6 0.2 -0.0 -1.5 -0.3 -1.6 0.5 2.8 0.5
Leg fat percentage (right) 0.8 3.0 9.6 1.1 -1.1 -2.5 -1.0 -3.1 -0.7 1.8 -1.0
Arm fat-free mass (right) 1.3 6.7 13.2 3.1 -2.3 -3.6 -2.8 -1.4 1.1 1.2 -3.6
Exposure to tobacco smoke outside home 2.6 3.5 7.6 2.5 -1.9 -2.1 -2.7 -1.5 -1.3 -0.3 -1.5
Comparative body size at age 10 3.6 9.8 16.2 3.7 -4.0 -3.5 -3.7 -2.2 -2.2 -1.4 -3.2
Number of full brothers 0.2 0.2 0.6 0.1 -0.2 -0.7 -0.3 -0.2 -0.3 0.5 0.7
Worry too long after embarrassment 0.2 0.4 0.9 -0.6 0.3 0.8 0.4 0.9 -0.2 0.3 0.7
Seen a psychiatrist for nerves, anxiety, tension or depression 5.5 7.1 12.9 -3.4 3.1 2.5 3.6 2.4 0.0 -0.7 3.2
Wheeze or whistling in the chest in last year 0.8 1.4 4.0 0.1 -0.2 -1.0 -0.4 -1.7 1.8 2.0 0.2
Number of children fathered 0.2 0.3 1.1 -0.0 0.1 -0.5 0.2 -1.1 -0.7 -0.4 0.2
Reason for reducing amount of alcohol drunk: Health precaution 0.8 0.9 2.5 -0.5 0.4 1.5 0.7 -0.6 -1.2 -1.6 -0.2
Age at first live birth 2.1 3.7 6.1 -2.0 1.9 1.8 1.9 2.5 -1.7 -1.1 2.2
Pulse wave peak to peak time 0.2 0.2 0.5 0.6 -0.3 -0.5 -0.2 0.5 -0.7 0.3 -0.3
Health satisfaction 0.1 0.1 0.3 -0.2 0.5 -0.2 0.2 0.1 0.4 0.3 -0.3
Shortness of breath walking on level ground 0.7 0.8 1.6 0.6 -0.9 -1.2 -0.8 -0.2 1.1 1.2 -0.5
Qualifications: College or University degree 2.2 7.0 11.9 -2.6 3.1 3.5 2.9 2.7 -0.9 -2.2 2.5
Eye problems/disorders: None of the above 0.2 0.2 0.9 0.3 -0.6 -0.2 -0.1 0.3 0.6 0.2 -1.0
Mouth/teeth dental problems: Loose teeth 1.0 1.2 4.5 0.8 -1.0 -0.4 -0.9 -2.1 1.3 0.4 -0.7
Emphysema/chronic bronchitis 3.7 4.1 7.0 -2.2 2.3 2.1 2.0 1.6 -1.0 -2.6 1.9
Medication for pain relief, constipation, heartburn 1.0 1.8 5.2 1.1 -0.3 0.8 -1.0 0.9 -1.5 -2.3 -1.8
Neck or shoulder pain in last month 0.2 0.3 1.0 -0.1 0.4 -0.2 0.0 -1.0 0.6 0.7 -0.5
Medication: Blood pressure 1.0 1.7 3.2 -1.7 1.4 0.1 1.6 -0.5 -0.1 1.8 1.5
Angina (self-reported) 2.0 2.6 6.6 -1.6 1.3 0.8 1.5 -0.2 0.9 2.5 2.6
Migraine (self-reported) 0.9 1.2 7.0 0.5 -0.5 -0.3 -0.3 2.7 -0.9 -0.1 -0.9
Medication: Ibuprofen 0.9 1.0 4.2 1.0 -1.1 -2.0 -1.2 -0.6 0.1 -0.4 -0.2
Medication: Allopurinol 0.4 0.6 1.1 -0.8 1.0 0.6 0.6 -1.0 0.2 1.0 0.6
Medication: Omeprazole 1.5 1.8 3.3 -1.7 1.4 1.4 1.6 -0.8 0.3 0.9 1.8
Medication: Seretide 50 evohaler 1.4 1.6 3.5 -1.7 1.6 0.8 1.9 -0.4 0.5 0.4 1.7
Mean time to correctly identify matches 0.2 0.4 1.6 0.2 -0.2 -0.1 -0.1 -1.3 -0.5 -0.6 0.8
Heart disease (mother) 0.6 0.7 1.5 -1.2 1.0 1.0 1.1 -0.1 0.4 0.6 0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.1 1.3 5.2 1.0 -1.1 -0.5 -1.1 -2.3 -0.4 -0.0 -0.9
Whole body fat mass 0.5 2.1 5.7 1.2 -0.7 -2.2 -1.2 -1.3 0.8 2.4 -0.8
Leg fat mass (right) 0.9 3.6 8.9 1.7 -1.4 -3.0 -1.7 -2.2 0.0 2.0 -1.7
Arm predicted mass (right) 1.3 6.5 14.0 3.1 -2.2 -3.5 -2.8 -1.0 1.1 1.1 -3.7
Pulse rate, automated reading 1.3 4.1 7.8 -2.3 2.8 2.6 2.4 1.7 -0.0 -0.5 2.0
Alcohol intake frequency. 0.1 0.2 0.5 -0.4 0.1 0.3 0.6 -0.3 -0.0 0.7 0.6
Comparative height size at age 10 0.2 1.0 3.8 0.1 0.2 -2.0 0.1 1.0 0.1 1.0 1.5
Number of full sisters 0.6 0.7 1.3 -0.7 1.1 1.0 0.5 0.3 1.1 0.9 0.6
Suffer from ‘nerves’ 0.8 1.3 3.5 -1.2 0.7 0.6 1.0 1.6 0.7 0.7 1.9
Overall health rating 0.4 0.8 2.4 0.5 -0.8 -1.3 -0.7 0.3 0.6 1.5 -0.5
Chest pain or discomfort 0.3 0.4 1.1 -0.3 -0.2 -0.8 0.1 -0.3 -0.9 1.1 0.4
Had major operations 1.0 1.1 2.8 -1.0 0.9 0.5 1.0 1.7 0.7 0.9 1.4
Age at last live birth 2.4 3.5 5.5 -2.1 1.6 1.3 2.0 2.3 -1.9 -1.6 2.2
Family relationship satisfaction 0.4 0.4 0.8 -0.6 0.6 0.7 0.6 -0.1 0.6 0.9 0.8
Leg pain on walking 3.3 4.2 10.0 2.2 -2.6 -3.2 -2.3 -1.2 0.2 0.7 -2.2
Qualifications: NVQ or HND or HNC or equivalent 1.8 2.2 3.7 1.7 -1.9 -1.6 -1.9 -0.3 -1.3 -0.7 -1.7
Commuting to job workplace: Car/motor vehicle 0.3 0.4 1.3 0.1 -0.1 -1.2 -0.4 -0.1 -1.1 -0.3 0.3
Illness, injury, bereavement, stress in last 2 years 1.5 1.8 5.1 2.0 -0.9 0.9 -1.6 0.8 0.5 -0.3 -2.3
Medication: Aspirin 2.0 2.6 6.7 -2.1 1.3 0.1 2.3 -0.4 -0.1 1.5 2.6
Supplements: Vitamin C 0.3 0.3 1.1 -0.5 0.4 -0.3 0.5 0.1 0.5 0.5 1.1
Knee pain experienced in last month 0.3 0.4 1.1 -0.6 0.5 0.1 0.2 0.7 1.1 0.8 0.6
Hypertension (Self-reported) 0.9 2.4 5.2 -2.3 1.9 0.5 2.1 -0.1 0.7 1.1 2.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.6 0.7 1.5 -0.9 1.2 0.2 0.9 -1.1 0.1 -0.2 0.9
Illnesses of father: Heart disease 1.2 1.7 3.1 -1.4 1.4 0.3 1.3 -0.2 -1.6 -1.4 1.7
Illnesses of siblings: Diabetes 0.2 0.3 0.9 0.1 0.2 0.6 -0.4 0.9 -0.1 -0.9 0.4
Smoking status: Previous 1.6 2.5 6.9 -1.6 1.0 0.3 1.7 0.8 -1.6 -2.6 1.7
Forced expiratory volume in 1-second (FEV1), predicted 0.9 1.9 4.4 -1.5 1.5 0.7 1.4 2.1 0.3 1.2 1.6
Whole body fat-free mass 0.9 5.1 10.2 2.8 -1.7 -3.2 -2.4 -0.1 1.6 1.3 -3.2
Leg fat-free mass (right) 1.1 5.7 9.5 2.8 -1.7 -3.0 -2.6 -0.2 2.4 2.0 -3.1
Arm fat percentage (left) 0.6 2.4 5.2 1.2 -1.0 -2.3 -1.4 -2.0 0.6 2.1 -0.8
Average weekly red wine intake 1.0 1.5 2.9 -1.2 1.4 1.7 1.2 1.4 0.8 -0.8 1.1
Handedness (chirality/laterality): Left-handed 2.4 2.9 6.2 -2.0 2.5 2.2 2.0 0.5 0.9 -0.8 1.7
Mood swings 1.1 2.0 2.9 1.7 -1.7 -1.3 -1.5 -0.6 0.8 1.7 -1.5
Loneliness, isolation 2.6 3.6 7.5 2.5 -2.0 -1.0 -2.6 -1.8 0.6 -0.2 -2.7
Long-standing illness, disability or infirmity 1.9 2.9 5.8 -2.4 1.9 1.3 1.9 1.3 1.1 0.6 2.4
Ever had bowel cancer screening 0.4 0.5 1.6 0.1 -0.3 -0.5 -0.4 1.2 1.3 0.5 -0.1
Diabetes diagnosed by doctor 1.1 1.8 11.6 -0.1 -0.6 -0.8 -0.1 -3.4 -0.7 0.8 0.6
Ever had stillbirth, spontaneous miscarriage or termination 2.6 2.8 5.3 -2.2 2.3 1.7 2.0 -0.2 0.9 1.5 1.6
Friendships satisfaction 0.6 0.8 2.0 -0.5 0.7 0.8 0.7 1.2 0.6 1.4 0.8
Qualifications: nursing, teaching 1.6 2.5 7.2 -1.1 0.8 1.3 1.0 1.9 -2.1 -2.7 0.7
Commuting to job workplace: Walk 0.9 1.0 6.7 0.5 -0.2 -0.9 -0.4 -2.6 0.2 0.5 -0.4
Eye problems/disorders: Cataract 0.3 0.3 0.9 -0.3 0.7 0.8 0.2 0.1 1.0 -0.1 0.8
Mouth/teeth dental problems: Mouth ulcers 0.5 0.7 1.7 -1.0 0.8 0.8 1.2 1.3 0.6 0.2 0.3
Medication for cholesterol 0.4 0.6 1.8 0.9 -0.6 -0.3 -0.8 0.9 -1.4 -0.5 -0.5
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.2 0.2 0.4 0.2 -0.3 -0.1 -0.4 0.6 0.7 -0.5 0.4
Back pain experienced in last month 0.3 0.4 2.4 -0.0 0.6 -0.1 -0.2 -0.4 1.6 0.3 -0.7
Mineral and other dietary supplements 1.1 1.4 2.8 1.2 -1.5 -0.8 -1.1 0.2 -0.7 -1.5 -1.7
Breast cancer (self-reported) 0.1 0.1 0.3 -0.1 0.1 -0.5 0.2 0.3 -0.5 -0.3 -0.2
Asthma (self-reported) 1.9 3.8 9.0 -1.7 2.2 1.3 1.2 0.9 3.0 2.4 2.0
Osteoporosis (self-reported) 0.8 0.9 2.5 0.5 -0.8 -0.8 -0.6 1.6 -1.1 -1.4 0.1
Osteoarthritis (self-reported) 1.5 2.0 3.5 1.5 -1.8 -1.9 -1.6 -0.8 0.0 -0.5 -1.9
Medication: Aspirin 1.4 1.8 5.1 -1.8 0.9 -0.4 2.0 -0.4 -0.2 1.1 2.3
Medication: Gliclazide 1.6 1.8 4.7 1.0 -1.7 -1.6 -1.1 -1.1 0.9 2.2 -0.3
Illnesses of father: None of the above (group 1) 0.9 1.1 2.4 1.4 -1.1 -0.7 -1.4 0.6 -0.4 0.4 -1.5
Smoking status: Current 0.9 1.5 4.6 0.2 0.2 0.2 -0.4 -1.8 2.1 2.0 0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.9 1.8 8.5 -1.1 1.1 0.5 1.2 2.9 -0.2 -0.4 1.3
Whole body water mass 0.9 5.2 10.4 2.8 -1.7 -3.1 -2.4 -0.2 1.6 1.3 -3.2
Leg predicted mass (right) 1.1 5.7 9.5 2.8 -1.6 -3.0 -2.6 -0.1 2.4 2.0 -3.1
Arm fat mass (left) 1.0 4.1 8.6 2.2 -1.6 -2.9 -2.2 -1.9 0.7 1.9 -2.0
Number of self-reported non-cancer illnesses 0.6 1.0 2.2 -1.5 1.1 0.3 1.0 1.1 0.5 0.4 1.4
Average weekly champagne plus white wine intake 0.5 0.7 2.3 0.3 0.1 0.7 -0.1 1.3 0.8 -0.3 -1.5
Miserableness 0.8 1.3 5.5 0.8 0.1 0.1 -1.0 -1.3 1.0 2.4 -0.7
Guilty feelings 4.2 6.4 10.2 -3.1 2.2 2.3 3.0 2.8 1.7 1.2 3.2
Wears glasses or contact lenses 3.3 3.8 8.8 -1.7 1.6 1.8 1.6 3.0 -2.0 -2.3 1.0
Ever taken oral contraceptive pill 0.8 0.9 1.9 -0.9 1.1 0.5 0.6 0.1 1.4 1.3 0.6
Hearing aid user 1.3 1.5 2.7 -1.6 1.5 1.4 1.6 -0.2 1.0 0.3 1.1
Mother’s age at death 0.2 0.3 1.1 -0.0 0.1 -0.5 -0.1 -0.4 0.9 -1.0 -0.3
Financial situation satisfaction 0.4 0.5 1.7 0.6 -1.0 -1.3 -0.7 -0.1 -0.7 0.1 -0.5
Tinnitus: Yes, now most or all of the time 1.4 1.6 4.8 -0.8 1.1 1.8 0.6 2.2 -0.8 -1.3 0.5
Commuting to job workplace: Public transport 1.4 1.7 6.2 -1.0 1.6 2.5 0.9 1.3 1.0 -0.2 0.2
Eye problems/disorders: Glaucoma 0.4 0.5 1.6 -0.5 0.8 -0.2 0.4 -1.3 -0.5 -0.3 0.8
Medication: Blood pressure 0.1 0.3 0.8 -0.2 -0.3 -0.7 0.1 -0.7 0.4 0.9 0.2
Pain type(s) experienced in last month: Hip pain 1.2 1.5 3.1 1.4 -1.2 -1.6 -1.8 -1.3 -0.3 0.0 -1.2
Supplements: Fish oil (including cod liver oil) 0.7 0.9 1.8 -0.9 0.9 0.2 0.7 -1.2 0.7 1.3 1.1
High cholesterol (Self-reported) 0.2 0.4 1.0 -1.0 0.4 -0.4 0.7 -0.4 -0.4 -0.6 0.9
Medication: Bendroflumethiazide 0.2 0.3 0.9 -0.6 0.6 0.5 0.5 0.3 0.6 0.9 -0.3
Medication: Paracetamol 0.7 1.1 5.0 -0.7 0.3 -0.3 0.7 -0.3 1.7 2.2 0.3
Medication: Lisinopril 0.3 0.3 0.9 -0.7 0.9 0.5 0.6 0.7 0.4 0.1 0.2
Medication: Atorvastatin 0.8 1.0 2.4 -1.0 1.2 1.6 0.8 -1.0 0.3 0.5 0.9
Illnesses of father: High blood pressure 3.2 4.0 8.7 -2.8 2.1 1.8 3.0 -1.0 0.4 -0.3 2.5
Alcohol drinker status: Never 1.6 1.9 4.6 1.2 -1.4 -1.4 -1.2 -0.1 -1.9 -2.1 -0.6
Ever smoked 1.3 2.3 5.0 -2.1 1.5 1.2 2.2 0.1 -0.6 -0.8 2.1
Basal metabolic rate 0.9 5.1 10.3 2.7 -1.6 -3.2 -2.4 -0.4 1.7 1.8 -3.0
Leg fat percentage (left) 0.8 3.1 8.2 1.3 -1.2 -2.4 -1.3 -2.9 -0.2 2.1 -1.2
Arm fat-free mass (left) 1.2 6.1 13.1 3.0 -2.0 -3.3 -2.7 -1.3 1.0 1.2 -3.6
Number of operations (self-reported) 0.8 1.1 8.0 0.1 -0.1 -0.1 0.3 2.8 0.6 0.6 -0.5
Average weekly beer plus cider intake 1.6 2.3 4.4 1.4 -1.5 -1.7 -1.5 -1.7 1.0 2.1 -0.6
Irritability 0.3 0.4 1.0 0.6 -0.9 -0.7 -0.5 0.4 -0.6 1.0 0.2
Risk taking 1.3 1.9 5.3 1.1 -0.6 -0.4 -1.3 -1.5 2.3 1.8 -1.0
Ever had prostate specific antigen (PSA) test 0.1 0.1 0.3 -0.2 -0.1 0.3 0.1 0.5 0.6 0.0 -0.2
Fractured/broken bones in last 5 years 0.8 1.0 6.2 -0.1 -0.6 -0.5 -0.2 2.5 -0.4 -0.9 0.6
Age started oral contraceptive pill 0.7 0.8 2.9 -0.2 0.3 0.8 0.2 1.4 -0.4 -1.7 -0.8
Diastolic blood pressure, automated reading 0.5 1.5 3.9 -1.5 2.0 1.3 1.8 0.1 -0.1 -0.6 0.8
Ever depressed for a whole week 1.7 2.0 4.3 -1.4 0.9 1.2 1.4 1.4 -2.1 -1.2 1.5
Unable to work because of sickness or disability 0.4 0.6 2.0 -0.9 0.3 -0.3 0.6 0.1 0.8 0.8 1.4
Commuting to job workplace: Cycle 1.2 1.4 3.0 -1.7 1.1 0.3 1.6 1.4 -0.1 -0.8 1.4
Myopia 0.2 0.3 1.0 -0.5 0.3 0.6 0.7 0.3 -1.0 -0.2 0.3
Vascular/heart problems diagnosed by doctor 0.7 1.8 3.7 1.8 -1.3 0.2 -1.7 1.0 0.3 -1.3 -1.9
Cholesterol lowering medication 0.5 0.8 2.3 -1.1 0.3 -0.4 0.9 -1.1 -0.6 -1.5 0.7
Medication: Omeprazole (e.g. Zanprol) 1.6 2.0 4.0 -1.4 1.6 1.5 1.2 -0.9 1.2 1.4 2.0
Pain experienced in last month 0.3 0.5 1.7 0.1 -0.6 0.3 0.1 -0.2 -1.1 -0.8 1.3
Supplements: Calcium 0.6 0.6 1.5 -0.6 0.9 0.9 0.6 1.2 -0.4 -0.2 0.9
Basal cell carcinoma (self-reported) 1.3 1.6 3.1 -1.6 1.6 0.8 1.6 0.7 0.9 0.1 1.8
Heart attack/myocardial infarction (self-reported) 2.5 3.3 9.1 -2.5 1.7 1.1 2.4 -0.2 -0.2 0.9 3.0
Deep venous thrombosis (DVT) (self-reported) 0.8 1.1 2.8 -1.1 -0.1 -0.4 0.9 1.7 -0.2 -1.1 1.5
Heart disease (siblings) 0.6 0.7 2.7 -0.5 0.1 -0.1 0.3 -1.6 0.5 1.2 1.0
Alcohol drinker status: Previous 1.4 1.6 7.3 -1.1 1.4 2.7 1.0 0.7 0.7 0.2 0.6
Pack years of smoking 0.1 0.1 0.3 -0.3 0.1 -0.2 0.3 0.4 -0.1 0.6 0.2
Impedance of whole body 3.4 17.1 44.6 -4.8 4.0 4.3 4.8 3.1 -0.3 1.5 6.7
Leg fat mass (left) 1.0 3.8 8.7 1.9 -1.5 -3.0 -1.9 -1.9 0.3 2.1 -1.9
Arm predicted mass (left) 1.2 6.3 13.0 3.1 -2.2 -3.5 -2.8 -1.0 0.9 1.1 -3.6