[Hub]/) : Traits : Impedance of leg (left) : ← →

chr22:30,914,473-32,995,751

Best TWAS P=3.81e-10 · Best GWAS P=1.16e-09 conditioned to 0.0609

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial SFI1 0.12 0.04 enet 21 0.09 8.5e-08 -5.3 5.3 1.3e-07 -0.79 0.14 0.86 FALSE
2 GTEx Colon Sigmoid SFI1 0.16 0.02 enet 36 0.05 5.4e-03 -4.1 5.2 1.6e-07 -0.54 0.10 0.42 FALSE
3 GTEx Esophagus Gastroesophageal Junction SFI1 0.15 0.07 lasso 3 0.06 3.7e-03 -6.1 6.0 1.6e-09 -0.95 0.01 0.96 FALSE
4 GTEx Esophagus Muscularis LIMK2 0.08 0.03 lasso 4 0.01 4.3e-02 -6.1 5.9 3.0e-09 -0.99 0.01 0.98 FALSE
5 GTEx Esophagus Muscularis SFI1 0.22 0.13 enet 20 0.15 3.7e-09 -4.7 5.9 2.7e-09 -0.83 0.05 0.95 FALSE
6 GTEx Muscle Skeletal SFI1 0.13 0.09 enet 22 0.10 1.7e-10 4.8 6.3 3.8e-10 -0.79 0.52 0.48 TRUE
7 GTEx Nerve Tibial SFI1 0.23 0.06 enet 16 0.14 1.9e-10 -4.1 5.5 4.1e-08 -0.79 0.15 0.85 FALSE
8 GTEx Thyroid SFI1 0.12 0.10 lasso 12 0.11 1.4e-08 -5.3 5.5 4.6e-08 -0.68 0.30 0.69 FALSE
9 NTR Blood DEPDC5 0.02 0.02 lasso 5 0.01 2.4e-05 -4.9 5.1 2.8e-07 -0.75 0.07 0.92 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma LIMK2 0.06 0.06 blup 47 0.06 9.3e-08 -4.9 5.6 2.1e-08 -0.81 0.04 0.95 FALSE
11 The Cancer Genome Atlas Rectum Adenocarcinoma RNF185 0.18 0.10 enet 6 0.12 9.7e-04 -5.2 -5.4 6.1e-08 0.83 0.01 0.64 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma RNF185 0.06 0.09 lasso 4 0.07 1.5e-07 -5.6 -5.6 2.1e-08 0.85 0.02 0.98 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma SELM 0.04 0.00 blup 54 0.01 4.8e-02 -4.4 5.2 2.4e-07 -0.59 0.05 0.29 FALSE