TWAS hub - CNTROB

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0500	0.0200	1.7e-03	0.006	0.015	0.013	0.015	0.006	4.8e-02	5.3e-03	8.5e-03	5.3e-03	5.5e-02
2	GTEx	Artery Tibial	0.1638	0.0375	2.6e-08	0.163	NA	0.136	NA	0.153	8.6e-13	NA	8.4e-11	NA	5.2e-12
3	GTEx	Esophagus Muscularis	0.0970	0.0440	7.1e-03	0.042	NA	0.012	NA	0.022	1.5e-03	NA	6.1e-02	NA	1.6e-02
4	GTEx	Lung	0.1518	0.0461	5.7e-05	0.063	NA	0.066	NA	0.046	1.4e-05	NA	9.5e-06	NA	1.8e-04
5	GTEx	Nerve Tibial	0.1712	0.0458	4.4e-07	0.092	NA	0.134	NA	0.105	4.8e-07	NA	9.7e-10	NA	6.7e-08
6	GTEx	Ovary	0.5810	0.1380	3.3e-04	0.057	NA	0.096	NA	0.034	1.6e-02	NA	2.4e-03	NA	5.2e-02
7	GTEx	Pancreas	0.1440	0.0540	1.8e-03	0.058	NA	0.029	NA	0.034	1.9e-03	NA	2.1e-02	NA	1.5e-02
8	GTEx	Skin Not Sun Exposed Suprapubic	0.1150	0.0450	2.5e-03	0.091	NA	0.075	NA	0.090	1.1e-05	NA	6.2e-05	NA	1.2e-05
9	GTEx	Spleen	0.2190	0.0820	4.6e-03	0.036	NA	0.025	NA	-0.010	4.1e-02	NA	7.4e-02	NA	6.9e-01
10	GTEx	Thyroid	0.1240	0.0420	2.6e-04	0.080	NA	0.030	NA	0.061	1.1e-06	NA	2.4e-03	NA	1.9e-05
11	METSIM	Adipose	0.0598	0.0194	6.4e-05	0.023	0.032	0.028	0.029	0.008	2.0e-04	1.3e-05	4.5e-05	3.0e-05	1.7e-02
12	ROSMAP	Brain Pre-frontal Cortex	0.0863	0.0234	7.8e-09	0.107	0.072	0.093	0.086	0.093	1.3e-13	1.5e-09	5.2e-12	3.6e-11	5.9e-12
13	YFS	Blood	0.0218	0.0082	3.9e-04	0.011	0.012	0.004	0.012	0.007	1.3e-04	5.8e-05	1.2e-02	5.6e-05	1.9e-03
14	TCGA	Colon Adenocarcinoma	0.3270	0.1020	1.5e-03	-0.003	-0.003	0.055	NA	0.038	5.6e-01	5.6e-01	4.2e-04	NA	2.8e-03
15	TCGA	Kidney Renal Clear Cell Carcinoma	0.0489	0.0265	8.7e-05	0.032	0.028	0.018	NA	0.026	1.4e-04	3.6e-04	3.7e-03	NA	5.8e-04
16	TCGA	Lung Squamous Cell Carcinoma	0.0953	0.0582	6.7e-03	-0.002	0.006	0.005	NA	-0.002	6.2e-01	6.0e-02	7.5e-02	NA	8.2e-01
17	TCGA	Skin Cutaneous Melanoma	0.4820	0.1420	9.6e-03	0.009	0.038	0.055	NA	0.036	1.9e-01	3.5e-02	1.4e-02	NA	3.9e-02
18	TCGA	Thyroid Carcinoma	0.1440	0.0620	5.5e-09	0.073	0.101	0.096	NA	0.099	1.2e-07	4.9e-10	1.3e-09	NA	7.5e-10

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Average weekly fortified wine intake	5.8	6.8	12.1	2.0	3.0	3.1	2.2	3.2	1.8	3.5	3.0	2.4	2.8	2.0	3.1	3.5	2.0	2.8	-2.5	0.1	1.9
Myopia	5.1	7.4	18.1	-4.3	-3.0	-3.3	-2.8	-3.0	-1.7	-2.4	-3.2	-1.8	-3.1	-1.6	-3.0	-2.4	0.4	-3.3	-0.1	2.7	-3.2
Smoking Status	4.6	11.1	23.0	4.1	3.5	4.0	-0.3	4.2	0.3	3.5	3.3	3.5	3.2	4.5	4.2	3.0	2.7	2.1	-2.3	-1.9	4.8
Average weekly red wine intake	4.6	6.7	13.1	2.4	2.6	3.3	1.1	2.7	0.8	3.6	2.8	2.4	2.7	2.2	3.5	3.2	1.7	2.0	-2.5	-2.5	2.6
Alcohol usually taken with meals	4.3	7.0	16.4	1.2	3.1	3.0	2.4	2.9	3.3	4.0	3.2	2.9	3.0	1.5	2.4	3.8	-0.7	3.1	-2.1	-0.3	1.2
Average weekly spirits intake	4.2	5.2	7.7	2.7	2.3	2.7	1.7	2.7	0.8	2.8	2.2	2.1	2.4	2.5	2.6	2.8	2.1	1.9	-2.3	-1.0	2.0
Diabetes (mother)	4.1	5.3	11.6	-1.2	-2.9	-2.9	-0.6	-3.4	-0.9	-2.3	-2.7	-2.8	-2.7	-1.9	-3.1	-2.0	-1.1	-2.7	0.2	0.9	-3.0
Mother’s age at death	3.8	4.8	9.6	1.8	2.7	2.2	3.0	2.7	2.0	3.1	2.6	2.5	2.5	1.0	2.1	2.3	1.0	2.7	-0.3	0.3	1.6
Medication: Bendroflumethiazide	3.5	5.4	12.0	-1.1	-2.6	-3.1	-2.2	-2.7	-1.9	-3.5	-2.6	-2.6	-2.7	-0.0	-2.8	-3.2	-0.5	-1.7	1.5	1.6	-2.2
Waist Hip Ratio (WHR)	3.3	14.8	31.4	4.8	4.5	4.5	5.6	4.1	4.3	5.0	4.4	2.5	4.4	0.4	3.9	4.3	0.0	4.4	-0.9	-0.5	3.4
Current tobacco smoking	3.3	5.4	13.3	2.6	2.7	2.9	0.3	3.0	0.1	2.1	2.6	2.2	2.7	2.5	2.9	2.0	2.1	1.9	-1.0	-0.8	3.6
Ever unenthusiastic/disinterested for a whole week	3.2	3.9	9.2	2.6	2.1	1.7	0.6	1.6	3.0	0.9	2.1	1.5	2.3	2.4	2.6	2.2	0.5	2.6	-0.1	-0.8	2.4
Medication: Allopurinol	3.1	4.2	11.3	-1.4	-2.5	-2.1	-1.6	-2.1	-0.9	-2.1	-2.6	-2.7	-2.5	-1.2	-2.5	-3.4	0.2	-2.8	-0.1	0.3	-1.7
Blood Red Count	3.0	29.4	56.9	-5.6	-6.0	-5.8	-7.2	-7.1	-1.0	-7.5	-5.7	-7.2	-5.2	-0.5	-5.2	-5.3	-4.5	-4.5	-1.9	-1.2	-7.4
Other serious medical condition/disability diagnosed by doctor	3.0	3.9	6.6	-0.8	-2.6	-1.9	-1.8	-2.5	-1.0	-2.4	-2.5	-2.2	-2.4	-2.0	-2.2	-1.8	-1.5	-2.5	0.3	-0.9	-2.3
Smoking status: Current	3.0	4.8	10.6	2.5	2.4	2.8	0.1	2.7	0.3	2.2	2.4	1.9	2.5	2.5	2.7	1.8	2.1	1.8	-1.6	-0.9	3.3
High blood pressure (siblings)	2.8	4.1	8.8	-1.1	-2.3	-2.2	-1.7	-2.5	-1.4	-3.0	-2.3	-2.9	-2.1	0.0	-2.2	-2.8	-0.9	-1.7	1.9	0.4	-2.0
Maternal smoking around birth	2.7	3.9	8.8	2.4	2.2	2.2	-0.1	2.4	0.4	2.5	2.2	3.0	2.3	1.1	2.2	2.6	-0.1	0.9	-1.6	-0.6	2.6
Hypothyroidism/myxoedema (self-reported)	2.7	5.4	9.5	-1.9	-2.9	-2.1	-2.9	-2.5	-2.2	-1.7	-2.8	-1.9	-2.7	-2.6	-2.1	-2.1	-0.7	-3.1	-2.2	-1.0	-2.8
Verbal and Numeric Reasoning (VNR)	2.6	6.3	13.6	-3.7	-2.8	-3.1	-1.0	-3.0	-2.2	-2.8	-2.7	-1.0	-2.6	-3.4	-2.3	-2.9	-1.4	-2.5	0.5	1.0	-3.4
Body Mass Index (BMI) (2010)	2.6	3.6	8.9	-2.7	-2.2	-2.6	-2.1	-2.0	-0.8	-3.0	-2.3	-1.3	-2.3	-1.0	-1.3	-2.0	-0.9	-2.1	0.3	-0.5	-1.8
Impedance of arm (right)	2.6	12.1	26.3	2.0	4.5	4.3	1.5	4.0	1.3	3.8	4.7	2.4	4.7	4.8	4.7	1.8	1.2	3.7	0.1	-0.2	5.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.6	5.6	10.9	-1.4	-2.7	-2.7	-3.3	-2.8	-3.2	-3.1	-2.6	-2.5	-2.7	-0.1	-2.8	-1.7	-0.4	-2.2	0.6	0.6	-2.6
Medication: Blood pressure	2.6	5.0	12.2	-1.3	-2.0	-3.0	-2.4	-2.1	-2.2	-3.5	-2.1	-1.5	-2.2	-0.1	-2.1	-2.9	-2.2	-2.0	1.9	2.5	-2.1
Breast Cancer	2.5	6.0	11.0	1.4	2.5	3.1	1.1	2.8	2.4	3.0	2.6	3.1	2.7	3.2	3.3	2.7	-0.4	1.4	-1.7	-2.1	2.3
Taking other prescription medications	2.5	3.9	7.2	-1.1	-2.5	-1.8	-2.4	-2.4	-1.4	-2.5	-2.5	-2.4	-2.3	-0.8	-2.0	-1.8	-1.9	-2.7	-0.1	-0.7	-2.0
Tinnitus: Yes, but not now, but have in the past	2.5	2.7	5.8	2.4	1.4	1.4	1.0	1.5	2.2	1.7	1.5	1.1	1.4	2.3	2.0	1.7	1.9	1.8	-0.3	0.3	1.8
Medication: Levothyroxine sodium	2.5	4.2	7.9	-1.6	-2.3	-1.3	-2.5	-1.9	-1.9	-1.3	-2.2	-1.2	-2.1	-2.4	-1.6	-1.7	-1.7	-2.7	-2.8	-1.8	-2.7
Commuting to job workplace: Car/motor vehicle	2.5	2.9	7.6	-1.4	-1.9	-2.2	-1.7	-2.0	-0.5	-1.8	-1.8	-1.6	-1.4	-1.7	-2.8	-1.3	-1.5	-1.7	0.3	1.2	-2.4
Hypothyroidism (self reported)	2.3	5.2	9.9	-1.9	-2.7	-1.9	-2.5	-2.4	-2.5	-1.2	-2.6	-1.9	-2.5	-3.0	-1.8	-2.3	-0.1	-3.1	-2.8	-0.7	-2.8
Eye problems/disorders: Diabetes related eye disease	2.3	2.5	5.4	1.4	1.8	1.4	2.2	1.7	1.4	2.2	1.9	1.8	1.8	-0.1	1.3	1.8	0.4	2.3	-1.2	1.0	0.6
Lung cancer (father)	2.3	2.7	6.7	-1.4	-1.9	-2.0	-1.3	-1.8	-1.3	-2.1	-1.9	-1.4	-1.9	-1.9	-1.4	-2.6	-1.1	-1.7	0.4	0.1	-1.8
Tense / ‘highly strung’	2.3	3.8	9.9	-0.8	-2.3	-2.2	-1.5	-2.4	-0.1	-2.4	-2.3	-3.0	-2.1	-1.3	-2.2	-3.2	0.1	-1.8	0.1	0.7	-2.1
Schizophrenia (2014)	2.2	4.8	12.9	2.0	1.9	2.9	1.9	2.4	2.5	2.4	1.9	1.2	1.9	2.8	2.5	1.7	1.1	1.4	-0.1	-2.8	3.6
Frequency of unenthusiasm / disinterest in last 2 weeks	2.2	3.0	9.4	-0.5	-2.0	-1.9	-3.1	-1.9	0.7	-2.4	-2.1	-1.1	-1.9	-1.0	-2.0	-1.9	-0.9	-2.3	1.5	-0.1	-0.9
Hearing difficulty/problems with background noise	2.2	3.5	12.4	2.8	1.8	1.5	2.3	1.9	0.5	1.6	1.7	1.2	1.8	1.6	1.8	2.3	1.0	1.1	1.9	0.0	3.5
Deep venous thrombosis (DVT) (self-reported)	2.2	2.8	6.2	-0.6	-1.8	-2.2	0.1	-1.7	-1.8	-2.5	-1.9	-2.5	-2.1	-0.3	-1.7	-2.5	1.0	-1.6	0.8	0.4	-1.1
Prostate Cancer	2.1	3.0	7.6	-1.4	-2.2	-1.9	-1.2	-1.5	0.6	-1.6	-2.3	-1.8	-2.1	-1.6	-1.5	-2.0	1.6	-1.0	-2.1	-0.2	-2.8
Lung FVC	2.1	10.8	46.0	-1.5	-3.7	-3.4	-6.8	-3.6	-1.5	-5.6	-3.7	-2.3	-3.6	2.0	-3.2	-2.9	-0.3	-3.0	0.6	-1.4	-2.9
Illnesses of siblings	2.1	3.0	7.0	1.0	2.1	1.6	1.1	2.1	1.4	2.5	2.1	2.4	1.9	0.3	1.7	2.6	1.3	1.8	-1.1	0.2	1.8
Impedance of arm (left)	2.1	9.9	23.8	1.0	4.1	4.0	0.6	3.5	1.2	3.3	4.3	2.1	4.3	4.9	4.3	1.5	0.6	3.4	0.3	-0.2	4.6
Schizophrenia vs Biploar Disorder	2.0	2.6	7.9	1.6	1.2	2.0	1.1	1.6	1.2	2.0	1.2	0.5	0.0	2.1	2.1	1.0	1.7	0.6	-0.7	-2.5	2.8
Medication for cholesterol	2.0	3.0	6.6	1.4	1.6	2.4	2.2	1.4	1.1	2.6	1.7	1.0	1.8	0.4	1.7	2.1	1.4	2.0	-0.9	-1.8	2.0
Ever taken oral contraceptive pill	2.0	2.2	4.3	2.1	1.8	1.6	0.6	1.6	-0.3	1.7	1.7	0.7	1.9	1.3	1.2	1.8	-0.4	1.3	1.8	1.0	1.9
Commuting to job workplace: Public transport	2.0	2.4	6.0	0.8	1.9	2.1	1.4	1.9	0.1	1.7	1.8	1.2	1.7	0.6	2.5	1.2	1.1	1.6	0.2	-1.4	2.4
Schizophrenia (2018)	1.9	4.0	13.0	1.6	1.3	2.7	0.8	1.7	2.4	1.8	1.3	1.1	0.0	3.6	2.3	1.4	0.4	1.0	-0.3	-3.6	3.1
Supplements: Glucosamine	1.9	2.5	8.0	2.2	1.5	1.0	2.8	2.1	1.9	1.2	1.2	0.2	1.1	1.1	1.8	1.7	1.2	2.4	0.0	-0.7	1.1
Ever smoked	1.9	3.4	7.7	2.8	1.6	2.3	0.0	2.0	1.1	2.3	1.6	1.9	1.5	2.0	2.6	1.8	1.1	1.1	-0.8	-1.6	2.7
Average weekly beer plus cider intake	1.9	2.7	4.8	-1.5	-2.1	-1.8	-1.8	-2.2	-1.4	-1.6	-2.0	-1.7	-1.7	-1.5	-2.1	-1.9	-0.6	-1.8	1.1	-0.5	-1.3
Heart disease (siblings)	1.9	2.3	8.2	-1.8	-1.7	-1.0	-2.9	-1.7	-1.8	-1.4	-1.6	-0.7	-1.3	-0.2	-1.3	-1.4	-1.4	-2.0	1.7	-1.3	0.0
Medication: Co-codamol	1.8	2.1	4.9	-1.3	-1.7	-2.0	-1.8	-1.5	0.2	-2.2	-1.7	-0.8	-1.7	-0.6	-1.2	-1.9	-0.7	-1.6	0.8	0.1	-1.5
Bilateral oophorectomy (both ovaries removed)	1.8	2.0	4.8	1.3	1.7	1.9	2.2	1.4	0.4	1.9	1.8	0.8	1.9	1.0	1.6	0.9	0.3	2.1	-1.0	-0.1	0.7
Fluid intelligence score	1.8	3.7	9.4	-2.4	-1.8	-2.2	-0.0	-2.3	-3.1	-2.0	-1.7	-0.8	-1.8	-3.0	-1.5	-2.6	-0.4	-1.8	0.7	1.3	-2.1
Blood clot in the leg (DVT)	1.8	2.3	5.3	-0.5	-1.6	-1.9	0.3	-1.6	-1.8	-2.3	-1.7	-2.2	-1.9	-0.5	-1.4	-2.3	1.1	-1.6	0.5	0.2	-0.9
Alcohol intake frequency.	1.8	4.1	12.9	0.7	-2.1	-1.9	-0.2	-2.5	-1.0	-2.7	-2.0	-3.6	-1.8	-2.1	-2.0	-2.8	-1.1	-0.6	-0.9	0.1	-3.6
Hayfever, allergic rhinitis or eczema	1.7	3.6	9.7	-0.9	-2.4	-2.3	-1.7	-2.6	-1.5	-1.7	-2.1	-3.1	-2.0	-1.0	-1.9	-1.4	-1.4	-2.9	0.1	0.2	-1.9
Mineral and other dietary supplements	1.7	2.3	5.9	-2.0	-1.5	-0.8	-2.4	-1.6	-1.8	-0.9	-1.2	-1.3	-1.1	-1.5	-1.9	-1.5	-1.4	-2.3	-0.2	0.5	-1.3
HbA1C	1.6	1.8	4.0	-1.0	-1.5	-1.2	-1.1	-1.8	1.1	-1.0	-1.4	-1.5	-1.4	-1.6	-1.3	-0.7	-2.0	-1.2	-0.7	-1.1	-1.7
Noisy workplace	1.6	2.0	5.6	-0.0	-1.5	-1.7	-1.9	-1.3	-0.6	-1.6	-1.6	-2.4	-1.5	0.6	-1.7	-0.8	0.2	-0.7	0.5	1.7	-2.1
Alcohol drinker status: Never	1.6	1.9	6.4	-0.0	-1.0	-1.3	-1.6	-1.4	-2.5	-2.4	-0.8	-2.2	-0.6	-0.7	-0.9	-1.4	-1.3	-0.8	0.1	-1.5	-1.3
Pain all over the body in last month	1.5	1.6	3.7	-1.2	-1.7	-1.4	-1.4	-1.7	-0.6	-1.2	-1.6	-1.2	-1.3	0.0	-1.2	-1.1	-1.4	-1.2	0.3	0.2	-1.9
Serious illness, injury or assault of a close relative in last 2 years	1.5	1.7	6.2	-1.7	-1.3	-0.7	-1.3	-1.9	-1.2	-0.3	-1.0	0.1	-1.0	-0.5	-1.1	-1.3	-0.8	-1.0	-2.2	1.4	-2.5
Standing height	1.5	14.6	61.2	0.7	3.2	3.2	7.8	3.9	1.2	6.4	3.0	5.9	2.6	-3.6	3.9	3.5	2.9	2.5	-0.5	-0.1	4.0
Mouth/teeth dental problems: Bleeding gums	1.5	2.0	5.2	-0.3	-1.7	-1.1	-1.8	-1.6	-1.1	-1.4	-1.6	-2.2	-1.4	0.2	-1.2	-1.8	0.0	-1.0	-1.2	0.7	-2.3
Mean time to correctly identify matches	1.5	2.8	7.1	2.3	1.5	1.9	2.7	1.8	1.6	2.1	1.4	0.9	1.5	-0.4	1.6	2.1	0.9	1.2	0.4	-1.5	2.1
Cholesterol lowering medication	1.5	2.2	5.2	-1.4	-1.4	-1.9	-2.0	-1.3	-0.5	-2.3	-1.5	-0.7	-1.5	-0.1	-1.2	-1.4	-0.5	-1.3	0.5	2.2	-2.2
Intelligence (Savage-Jansen 2018)	1.4	4.3	9.1	-3.0	-2.3	-2.4	-0.6	-2.6	-1.9	-2.0	-2.3	-1.0	-2.1	-2.8	-2.0	-2.6	-1.3	-1.7	0.9	0.8	-2.9
Ovarian Cancer	1.4	1.8	4.2	1.7	1.6	1.4	1.4	1.3	1.7	1.6	1.6	1.0	1.6	0.9	1.6	1.1	-0.2	2.0	-1.0	0.8	0.4
Systolic Blood Pressure	1.4	7.0	18.0	-0.9	-2.1	-2.2	-4.2	-2.9	-2.2	-3.4	-1.8	-3.1	-1.7	2.5	-3.0	-3.3	-4.1	-2.3	1.0	1.6	-2.3
Exposure to tobacco smoke at home	1.4	1.6	2.9	1.7	1.1	1.5	1.0	1.1	1.2	1.0	1.2	0.5	1.1	1.2	1.6	1.4	0.7	1.4	-1.0	-1.3	1.6
Long-standing illness, disability or infirmity	1.4	2.1	4.3	0.0	-1.9	-1.2	-1.6	-1.7	-0.7	-1.5	-1.7	-0.7	-1.6	-0.6	-1.2	-0.8	-2.1	-1.8	-1.5	-1.9	-1.8
Ever had bowel cancer screening	1.4	1.7	3.1	-1.7	-1.5	-1.5	0.2	-1.4	-0.3	-0.7	-1.4	-0.5	-1.4	-1.5	-1.7	-1.3	-1.7	-1.6	0.1	0.9	-1.8
Eye problems/disorders: Glaucoma	1.4	1.7	7.8	0.9	1.4	1.1	2.2	1.1	0.7	0.9	1.4	1.4	1.2	0.4	1.2	0.9	-2.8	1.3	-1.2	-0.1	-0.2
Age started oral contraceptive pill	1.4	1.8	7.3	-1.8	-1.4	-1.1	-0.4	-2.0	-1.0	-1.3	-1.1	-1.0	-0.8	-0.7	-1.0	-1.5	-1.7	-0.1	-1.0	-1.0	-2.7
Blood Eosinophil Count	1.3	9.7	17.9	-2.5	-2.9	-3.2	-3.0	-2.8	-3.8	-3.8	-2.9	-1.9	-3.1	-4.0	-2.1	-2.6	-0.8	-4.0	-4.1	1.8	-4.2
Height	1.3	25.6	102.0	-0.1	3.7	4.3	10.1	5.2	2.1	9.2	3.4	8.3	3.0	-6.2	4.4	4.5	3.6	3.1	-0.9	-0.3	4.6
Alcohol intake versus 10 years previously	1.3	1.9	10.6	1.9	1.2	0.9	3.2	1.1	1.8	0.8	1.1	-0.1	1.3	-0.6	0.9	0.0	-0.4	1.5	2.2	0.1	1.2
Depression (self-reported)	1.3	1.5	4.1	-0.1	-1.2	-1.2	-2.0	-1.0	-0.9	-1.7	-1.3	-2.0	-1.3	-0.3	-1.4	-0.8	-1.2	-1.0	1.6	-0.9	-0.6
Number of full brothers	1.3	1.6	2.8	-1.4	-1.2	-1.5	-1.4	-1.1	-0.3	-1.5	-1.4	-1.5	-1.1	0.7	-1.6	-0.5	-0.8	-1.4	1.7	1.4	-1.3
Worry too long after embarrassment	1.3	2.1	11.4	-0.7	-1.5	-1.8	0.4	-1.9	1.2	-1.0	-1.3	-0.8	-1.3	-3.4	-1.7	-1.4	0.0	-1.3	0.7	1.2	-1.3
Supplements: Vitamin C	1.3	1.5	4.0	0.8	1.4	1.3	0.7	1.4	1.5	1.3	1.4	1.6	1.4	1.3	1.1	1.4	-0.4	2.0	0.1	-0.2	0.6
Heel T-Score	1.2	9.3	28.5	3.4	2.8	3.3	-2.2	3.1	2.2	1.4	3.2	2.9	3.3	2.7	3.0	5.3	-1.7	2.3	-4.0	-4.0	1.3
Happiness	1.2	1.4	3.2	-1.2	-1.5	-1.8	-0.8	-1.3	0.6	-1.3	-1.5	-0.8	-1.6	-0.5	-1.1	-1.5	-0.6	-1.2	-0.1	0.3	-1.8
Miserableness	1.2	2.1	4.7	-0.1	-1.7	-1.4	-1.6	-1.7	-0.1	-2.0	-1.6	-0.7	-1.6	-1.7	-1.7	-1.9	-1.4	-2.2	-0.2	0.1	-1.3
Financial situation satisfaction	1.2	1.5	3.8	-1.5	-1.5	-1.4	-1.9	-1.4	0.2	-1.5	-1.5	-1.1	-1.5	1.0	-0.6	-0.9	-0.6	-1.7	0.6	0.1	-1.1
Supplements: Fish oil (including cod liver oil)	1.2	1.6	3.8	1.6	1.2	0.6	2.0	1.3	1.6	0.5	1.1	1.4	0.8	1.1	1.7	0.9	0.5	1.8	-0.2	-1.6	1.3
Mean Putamen Volume	1.1	1.2	3.8	-1.1	-1.2	-1.0	-0.6	-1.2	-0.2	-0.4	-0.9	-1.0	-1.2	-2.0	-0.8	-1.3	-1.2	-1.3	-1.6	-0.7	-0.8
High blood pressure (mother)	1.1	1.6	4.7	-0.3	-1.0	-1.2	-0.5	-1.4	-0.7	-1.6	-1.0	-2.2	-0.9	-0.6	-1.3	-2.1	-1.4	-1.1	-0.1	1.5	-1.6
Body mass index (BMI)	1.1	4.6	12.2	-0.7	-2.7	-2.7	-1.3	-1.9	-2.4	-3.5	-3.0	-2.0	-2.8	-0.6	-1.7	-2.4	0.4	-2.9	0.6	-0.2	-2.1
Hair/balding pattern: Pattern 2	1.1	1.4	6.8	1.8	0.9	0.5	0.6	1.0	-0.3	1.1	1.0	0.7	1.1	1.5	1.4	0.2	2.6	1.0	-1.6	1.0	0.4
Neuroticism score	1.1	2.3	5.5	0.2	-2.0	-1.7	-1.2	-1.8	0.8	-2.1	-1.9	-1.1	-1.7	-2.3	-1.6	-1.9	-0.8	-1.9	-0.3	-0.5	-1.1
Number of live births	1.1	1.5	4.8	-0.2	-1.1	-1.1	-2.2	-1.3	-1.7	-2.0	-1.2	-1.2	-1.2	0.1	-0.6	-1.0	-0.4	-1.3	2.0	-0.1	0.5
Gout (self-reported)	1.1	1.5	3.4	-0.5	-1.4	-1.1	-1.1	-1.3	-0.4	-0.8	-1.4	-1.8	-1.3	-0.8	-1.8	-1.8	0.8	-1.2	-0.6	0.9	-1.2
Medication: Amlodipine	1.1	1.5	5.6	-0.5	-1.2	-1.0	-1.6	-1.3	-2.4	-2.0	-1.2	-1.5	-1.2	0.9	-1.2	-1.1	-0.5	-1.4	-0.2	-0.6	-0.2
Family relationship satisfaction	1.1	1.3	3.1	0.7	0.9	1.2	1.1	0.8	1.6	1.7	1.0	1.4	1.0	1.2	1.4	0.3	-1.0	0.3	-0.3	-1.6	1.6
Commuting to job workplace: Walk	1.1	1.2	4.2	1.0	1.2	1.5	0.5	1.3	0.3	1.2	1.1	0.2	0.9	2.0	1.0	0.5	1.3	1.8	-0.2	-0.5	1.0
Breast cancer (self-reported)	1.1	1.3	3.3	-0.1	-1.4	-1.0	-0.9	-1.4	-0.9	-0.8	-1.4	-1.4	-1.2	-1.2	-1.8	-1.3	-0.4	-1.7	-0.7	-0.5	-1.1
Medication: Lisinopril	1.1	1.4	8.7	0.6	1.1	1.0	-1.0	1.2	-1.0	1.1	1.1	1.4	0.9	2.9	1.0	1.1	0.6	0.3	-0.6	0.7	1.3
Ever depressed for a whole week	1.1	1.3	4.6	0.7	0.9	1.3	-0.2	0.9	0.8	0.9	1.0	2.1	1.1	0.7	1.5	1.1	0.6	1.1	-1.9	-1.3	1.2
Type 2 Diabetes (T2D) (2012)	1.0	1.2	9.5	-0.4	-0.7	0.0	-1.4	-0.4	-1.1	0.5	-0.7	-1.1	-0.5	-0.3	-0.6	-0.4	0.1	-0.5	-3.1	-1.2	-1.7
Allergy or Eczema	1.0	2.6	8.6	-0.7	-2.0	-2.0	-1.7	-2.3	-0.9	-0.8	-1.7	-2.9	-1.6	-0.3	-1.8	-1.1	-0.9	-2.5	-0.6	-0.1	-1.4
Sitting height	1.0	7.1	26.6	1.4	2.1	1.8	5.2	2.6	-0.3	4.6	2.0	4.4	1.6	-3.6	2.3	2.2	1.9	1.1	-0.3	0.8	2.9
Chronic bronchitis/emphysema (father)	1.0	1.2	3.9	1.7	0.7	0.5	1.1	0.7	0.1	1.2	0.7	1.2	0.9	0.7	0.5	1.0	1.1	-0.0	1.6	1.5	2.0
Number of incorrect matches in round	1.0	1.7	8.1	1.2	1.2	1.1	0.7	1.1	2.9	0.4	1.3	0.3	1.2	1.9	1.4	1.1	-0.3	1.2	0.3	-1.3	1.8
Past tobacco smoking	1.0	1.8	4.3	-2.0	-0.9	-1.6	0.5	-1.4	-0.4	-1.6	-0.8	-1.4	-0.7	-2.0	-1.9	-1.0	-0.1	0.0	0.9	2.1	-1.8
Frequency of tiredness / lethargy in last 2 weeks	1.0	1.7	6.3	0.8	-1.5	-1.6	-2.5	-1.0	0.1	-1.9	-1.6	-1.2	-1.5	0.7	-0.8	-1.4	-0.7	-2.0	-0.3	-0.2	-0.8
Illness, injury, bereavement, stress in last 2 years	1.0	1.2	3.8	0.2	1.1	1.2	0.0	1.2	-0.4	1.0	1.1	0.5	1.1	1.1	1.4	1.4	2.0	1.0	-0.4	-0.3	1.7
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.0	4.8	1.5	0.7	0.8	-0.2	0.6	-0.9	0.5	0.8	2.2	0.7	1.4	0.9	0.6	-0.3	0.0	0.5	-0.8	2.0
Impedance of whole body	1.0	5.0	12.0	0.4	3.0	3.0	0.1	2.3	1.3	2.5	3.2	0.6	3.3	3.4	2.7	1.0	0.3	2.3	0.4	0.3	3.5
Bipolar Disorder or Schizophrenia	0.9	2.2	10.0	1.0	1.0	2.2	0.2	1.3	0.7	1.3	1.0	1.2	0.0	2.5	1.6	1.4	-0.0	0.9	-0.3	-3.2	2.2
Blood White Count	0.9	7.0	16.5	0.0	-2.8	-2.5	-1.6	-2.6	-2.5	-2.5	-2.9	-3.8	-3.1	-3.0	-2.4	-2.6	-1.1	-3.2	-1.7	2.6	-4.1
Chronotype (morning person)	0.9	2.0	6.8	-0.2	-0.6	-1.4	-2.4	-1.1	-0.6	-1.8	-0.7	-2.6	-1.0	2.2	-1.7	-0.9	-0.6	-0.1	0.7	1.7	-1.7
Medication for cholesterol, blood pressure or diabetes	0.9	1.4	5.0	-1.6	-0.9	-1.3	-0.7	-1.2	-2.2	-1.3	-0.9	-0.4	-1.1	-1.6	-0.9	-1.2	-0.2	-0.5	0.5	0.9	-2.0
Number of children fathered	0.9	1.0	2.6	0.7	1.2	1.3	0.6	1.6	-0.4	1.4	1.1	1.0	1.0	-0.1	1.3	1.4	0.6	0.9	-0.2	-0.3	1.2
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.1	7.8	0.4	0.4	-0.0	1.0	0.0	-0.9	-0.2	0.5	0.6	0.4	-0.1	0.4	0.5	-1.7	0.6	2.8	-1.5	1.7
Illnesses of siblings: Diabetes	0.9	1.1	2.6	0.6	-1.3	-0.7	-0.8	-1.0	-0.9	-1.1	-1.1	-0.9	-1.0	-0.5	-0.7	-1.1	-0.9	-1.6	-1.4	-1.1	-1.4
Major Depression (MDD)	0.8	0.9	2.5	1.6	1.1	0.8	0.5	1.1	0.4	-0.9	1.1	1.0	0.0	1.1	1.5	0.3	-0.5	1.0	0.1	-1.2	0.9
Reaction Time	0.8	1.6	5.7	2.4	1.3	1.4	1.5	1.2	0.8	1.4	1.3	0.0	1.3	-0.4	1.1	1.2	-0.1	0.9	0.9	-0.8	1.9
Coronary Artery Disease (CAD)	0.8	0.9	2.4	1.1	0.8	1.1	0.3	1.5	0.8	1.3	0.5	0.4	0.7	0.2	0.9	1.5	1.2	0.4	0.6	1.4	0.8
BMI	0.8	4.5	13.1	0.3	-2.3	-2.8	-1.3	-2.0	-2.9	-3.6	-2.6	-2.2	-2.5	0.3	-1.2	-2.9	0.8	-2.1	-0.3	1.1	-2.6
Hearing difficulty/problems: Yes	0.8	1.3	4.7	2.2	0.9	1.0	1.6	1.0	-0.3	0.8	0.9	0.9	1.0	-0.1	1.3	1.4	0.8	0.4	-0.0	-0.8	2.0
Allergy	0.8	1.9	5.8	0.1	1.6	1.8	-0.4	1.9	1.1	1.2	1.5	2.4	1.4	1.1	1.6	1.2	0.5	2.1	-0.7	-0.5	1.1
Breastfed as a baby	0.8	1.0	7.4	1.4	0.4	0.7	-0.7	0.7	-2.2	0.3	0.2	0.6	0.2	0.9	0.4	0.2	2.7	0.6	-0.7	0.6	0.5
Hair/balding pattern: Pattern 4	0.8	2.0	4.4	-0.3	-1.6	-1.3	0.3	-1.0	-1.9	-1.4	-1.9	-1.7	-2.1	-1.8	-1.3	-1.0	-1.0	-1.8	0.8	-0.8	-1.6
Pulse wave reflection index	0.8	1.0	4.6	-1.0	-0.3	-0.7	-1.8	-0.5	-1.4	-0.6	-0.4	-0.2	-0.4	1.5	-0.7	0.1	0.6	0.6	1.6	2.1	-0.3
Glaucoma (self-reported)	0.8	0.9	10.1	-0.7	-0.1	0.2	1.0	-0.3	0.4	0.0	-0.0	0.4	-0.1	-1.0	-0.2	-0.4	-3.2	0.2	-0.8	-1.2	-1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	0.9	3.8	0.0	-0.6	-1.1	-0.4	-0.7	-0.8	-1.0	-0.6	-1.1	-0.8	-0.9	-1.2	-0.8	-1.1	-0.8	-0.2	1.5	-1.9
Pain type(s) experienced in last month: Hip pain	0.8	1.0	4.2	1.6	0.8	0.7	0.6	1.0	0.6	0.4	0.9	0.0	0.9	1.1	0.9	0.5	0.2	0.7	0.8	-1.7	2.1
Leg fat percentage (left)	0.8	2.7	9.0	-1.0	-1.9	-2.0	-1.0	-1.4	-1.2	-3.0	-2.2	-2.1	-1.9	-0.1	-1.1	-2.3	0.2	-2.2	0.6	0.2	-1.4
Fractured/broken bones in last 5 years	0.8	1.1	3.0	-0.1	0.9	1.4	1.3	1.1	0.3	1.5	0.8	0.8	0.6	0.4	1.7	0.5	1.7	0.8	-1.4	0.5	0.5
Lung FEV1/FVC ratio	0.7	3.8	10.9	-0.9	-2.0	-1.9	-1.6	-1.3	-2.1	-2.1	-2.3	-2.5	-2.2	-2.9	-1.4	-0.8	1.2	-1.8	-1.7	1.1	-3.3
Hand grip strength (right)	0.7	1.9	5.5	0.6	1.1	1.2	1.2	1.2	2.1	1.8	1.2	2.3	0.8	-1.3	1.3	2.3	-0.2	0.9	-1.5	-0.9	0.4
Age when periods started (menarche)	0.7	1.7	4.3	-0.7	-1.3	-1.5	-0.7	-1.4	-0.5	-1.6	-1.4	-1.0	-1.3	-1.3	-1.3	-1.6	0.1	-1.7	-1.1	1.6	-2.1
Qualifications: CSEs or equivalent	0.7	0.9	8.0	0.7	-0.5	-0.0	-2.8	-0.3	-0.7	-0.7	-0.4	-0.7	-0.3	2.1	0.1	0.3	0.6	-0.5	-0.6	0.7	-0.4
High blood pressure	0.7	1.8	6.4	-0.2	-0.9	-1.3	-1.3	-1.3	-1.3	-1.6	-0.9	-1.2	-0.7	1.4	-1.1	-2.3	-1.8	-0.9	2.5	0.7	1.0
Stomach or abdominal pain in last month	0.7	0.9	1.8	0.9	1.3	1.0	-0.3	1.0	-1.1	0.4	1.3	0.9	1.3	0.8	1.1	0.6	-0.9	1.1	-0.5	0.3	1.0
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.1	2.3	0.6	-1.1	-0.8	-1.4	-1.0	0.7	-1.5	-1.1	-1.0	-1.1	-1.0	-0.8	-1.3	-1.3	-1.0	0.2	-1.2	-0.5
Financial difficulties in last 2 years	0.7	0.9	2.6	0.2	-0.8	-0.9	-1.3	-0.9	-1.0	-0.9	-0.8	-1.2	-0.8	0.4	-1.1	-1.6	-0.8	-1.0	1.4	0.8	0.2
Mouth/teeth dental problems	0.7	1.1	4.3	0.9	1.0	0.6	2.1	0.8	-0.2	0.7	1.0	1.2	0.7	0.2	0.8	0.7	0.5	0.5	1.8	-0.6	2.1
Trunk fat-free mass	0.7	3.8	26.8	0.2	-0.7	-0.4	4.6	0.5	-0.5	1.8	-1.0	2.7	-1.3	-5.2	0.3	1.2	2.0	-0.9	-0.7	-0.4	-0.1
Falls in the last year	0.7	0.9	2.0	1.0	0.9	1.0	-0.0	1.1	0.2	1.0	0.8	1.2	1.0	0.8	0.8	1.4	1.4	0.2	-1.1	0.4	1.3
Medication: Cholesterol lowering	0.7	1.0	4.4	1.6	1.0	1.0	0.8	1.3	1.6	1.1	0.8	0.3	0.9	0.2	0.4	2.1	0.0	0.5	0.2	0.4	1.2
Trunk predicted mass	0.7	4.0	27.0	0.2	-0.6	-0.3	4.7	0.6	-0.5	1.8	-1.0	2.8	-1.2	-5.2	0.4	1.3	2.2	-0.8	-0.6	-0.4	0.0
Ever highly irritable/argumentative for 2 days	0.7	0.8	4.2	0.3	-0.9	-0.8	-2.1	-0.7	1.0	-0.7	-0.8	-0.5	-0.7	0.9	-0.7	0.3	1.2	-1.4	-0.9	0.0	-0.4
Arm fat-free mass (right)	0.7	3.6	24.4	-1.1	-2.0	-1.7	2.8	-0.8	-1.2	-0.1	-2.4	0.9	-2.5	-4.9	-1.0	-0.2	1.4	-1.9	-0.6	0.0	-1.6
Exposure to tobacco smoke outside home	0.7	0.9	3.1	0.7	0.6	1.4	-0.3	0.7	-0.2	0.9	0.7	0.4	0.9	1.8	0.9	0.9	0.3	1.0	-0.4	-1.6	1.2
Eye problems/disorders: None of the above	0.7	0.8	6.5	0.8	0.6	0.6	0.4	0.8	-0.1	0.8	0.5	-0.1	0.4	-0.4	1.0	0.9	2.5	-0.3	-1.1	0.6	1.0
Comparative height size at age 10	0.7	3.7	20.6	0.9	1.3	1.6	4.5	1.6	-0.7	3.0	1.3	2.9	0.8	-2.9	1.2	1.4	0.3	0.5	-1.4	-1.1	2.0
Suffer from ‘nerves’	0.7	1.1	2.5	-0.6	-1.2	-1.1	-1.1	-1.4	1.2	-1.3	-1.1	-0.7	-1.0	-1.6	-0.9	-1.0	-1.3	-1.0	0.6	-0.3	-0.9
Hypertension (Self-reported)	0.7	2.1	6.3	-0.4	-1.2	-1.4	-1.7	-1.5	-1.4	-1.8	-1.1	-1.2	-0.9	1.1	-1.2	-2.4	-1.5	-1.3	2.5	0.6	0.9
Friendships satisfaction	0.7	0.8	3.0	1.5	0.9	0.8	1.7	0.7	0.4	0.9	0.9	0.2	0.8	1.4	1.1	0.9	-0.3	0.5	-0.3	-0.1	0.7
Eye problems/disorders: Cataract	0.7	0.8	3.7	-1.1	-0.4	-0.5	-1.4	-0.4	-1.9	-1.1	-0.4	0.8	-0.3	0.4	-0.2	-0.4	-1.0	0.0	1.8	-0.6	-0.1
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	5.9	0.9	0.9	1.0	-0.5	0.8	1.4	0.8	1.0	0.3	1.3	1.2	0.4	0.8	-0.0	0.9	-2.4	0.6	-0.9
Osteoporosis (self-reported)	0.7	0.9	5.7	-1.5	-0.5	-0.8	-1.6	-0.6	-2.4	-0.9	-0.5	0.1	-0.5	0.7	-0.6	-0.3	0.1	-0.1	0.7	0.9	-0.7
Illnesses of father: None of the above (group 1)	0.7	0.8	2.6	-1.4	-0.9	-0.7	0.1	-1.2	-0.8	-0.6	-0.8	-0.6	-0.8	-1.4	-0.9	-1.6	1.2	-0.3	-0.2	0.5	-0.8
Wears glasses or contact lenses	0.7	0.8	3.5	-0.2	0.7	1.0	1.9	0.4	-0.1	1.5	0.8	-0.0	0.8	0.5	0.8	0.9	0.7	1.2	0.4	0.3	1.1
Arm fat-free mass (left)	0.7	3.4	26.2	-0.4	-1.6	-1.3	3.7	-0.4	-0.7	0.3	-2.0	1.4	-2.1	-5.1	-0.5	0.2	1.5	-1.7	-0.4	-0.4	-1.0
Number of operations (self-reported)	0.7	1.0	2.1	1.3	0.9	1.2	0.4	0.7	-0.5	0.3	0.9	1.0	1.0	1.1	1.4	-0.3	0.9	1.4	-0.3	-1.3	1.4
Arm predicted mass (left)	0.7	3.4	24.8	-0.4	-1.5	-1.1	3.8	-0.3	-1.1	0.5	-1.9	1.6	-2.1	-5.0	-0.4	0.3	1.7	-1.8	-0.5	-0.3	-0.9
Primary Biliary Cirrhosis	0.6	0.8	3.5	-1.9	-0.8	-0.9	-0.8	-0.5	-0.5	-0.3	-0.8	-0.3	-0.9	0.4	-0.8	-1.5	0.4	-1.7	-0.7	-0.3	-0.4
Frequency of depressed mood in last 2 weeks	0.6	0.9	3.5	1.0	-0.9	-0.5	-1.9	-1.0	1.1	-1.2	-0.8	-0.7	-0.7	0.2	-0.6	-1.3	-0.8	-0.9	0.4	-0.8	0.0
Had other major operations	0.6	0.8	3.2	0.0	0.5	1.0	-0.3	0.6	-1.0	0.6	0.5	1.8	0.4	0.6	1.1	-0.8	0.9	-0.1	-0.4	-1.4	1.5
Medication: Lansoprazole	0.6	0.7	6.9	0.2	-0.4	-0.4	-2.6	-0.4	-0.1	-0.9	-0.5	-0.5	-0.3	0.5	-0.6	0.6	1.3	-0.0	0.2	1.2	-0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.9	4.8	-1.5	-1.5	-1.6	-2.1	-1.4	-2.2	-1.0	-1.5	0.3	-1.9	-1.2	-1.4	-0.9	0.3	-1.3	0.2	0.7	-1.4
Qualifications: O levels/GCSEs or equivalent	0.6	0.9	4.5	-1.3	0.4	-0.0	0.6	0.5	-0.9	1.0	0.4	0.4	0.2	-0.4	0.6	2.1	1.9	0.8	-0.8	1.5	-0.4
Comparative body size at age 10	0.6	1.7	5.5	-0.9	-1.6	-1.7	-0.1	-0.7	-0.5	-1.2	-1.8	-1.2	-1.9	-0.9	-1.2	-0.6	2.3	-1.4	-0.7	0.6	-1.8
Age at first live birth	0.6	1.0	2.9	0.1	1.2	1.0	0.8	1.1	0.5	1.7	1.3	1.5	1.1	0.6	0.5	0.9	0.7	1.1	-0.9	-0.7	1.3
Migraine (self-reported)	0.6	0.7	4.2	0.7	0.0	0.1	-0.9	-0.2	1.6	-0.9	0.2	0.0	0.1	-0.1	-0.1	0.7	-2.1	0.2	0.8	-1.6	-0.0
Medication: Seretide 50 evohaler	0.6	0.7	5.2	-0.3	-0.6	-0.1	-0.5	-0.4	-1.5	-0.1	-0.6	-0.4	-0.6	0.3	-0.1	0.3	0.9	-0.3	-2.3	-1.1	-0.6
Arm predicted mass (right)	0.6	3.2	23.3	-0.8	-1.7	-1.5	2.9	-0.5	-1.0	-0.0	-2.1	1.2	-2.2	-4.8	-0.8	0.1	1.2	-1.7	-0.5	-0.2	-1.3
Age at last live birth	0.6	0.8	3.0	0.2	0.8	0.8	0.3	1.0	-0.1	1.7	0.8	1.4	0.7	0.2	0.7	1.0	1.0	0.3	-1.6	-0.8	0.9
Leg pain on walking	0.6	0.7	3.2	1.1	-0.7	-1.0	0.1	-0.7	-0.4	-0.7	-0.7	-1.8	-0.6	0.4	-0.8	-0.6	-1.5	-0.6	0.9	-0.3	-0.3
Handedness (chirality/laterality): Left-handed	0.6	0.8	4.7	0.8	-0.4	-0.5	-0.5	-0.6	-0.4	-1.2	-0.2	-1.5	-0.5	0.5	-0.4	-1.3	-2.2	-0.8	0.6	-0.0	-0.6
Mood swings	0.6	1.1	2.5	0.4	-1.2	-1.1	-1.1	-1.0	0.9	-1.1	-1.2	-0.4	-1.0	-1.5	-1.6	-0.9	-0.9	-1.4	-0.7	-0.5	-1.0
Osteoarthritis (self-reported)	0.6	0.8	5.2	1.4	0.5	0.4	2.3	0.5	0.1	0.9	0.5	0.4	0.3	0.2	0.5	-0.3	0.7	0.9	1.1	0.3	1.5
Commuting to job workplace: Cycle	0.6	0.7	2.3	-1.2	-0.9	-0.9	-0.7	-1.2	-0.6	-0.8	-0.7	-0.5	-0.9	-0.8	-1.0	-0.1	-0.1	-0.3	-0.3	0.6	-1.5
Vascular/heart problems diagnosed by doctor	0.6	1.5	6.8	-0.1	0.8	1.2	0.9	0.9	0.4	1.3	0.8	1.0	0.6	-1.5	1.0	1.9	1.9	0.9	-2.6	-0.7	-1.0
Basal cell carcinoma (self-reported)	0.6	0.8	5.2	2.3	0.1	-0.1	0.5	0.1	-2.3	-0.7	0.1	0.4	-0.0	-0.4	-0.3	0.4	-0.4	0.1	1.1	0.0	0.8
Depression (Nagel 2018)	0.5	0.8	4.7	1.2	-0.5	-0.2	-2.2	-0.3	1.5	-1.0	-0.6	-0.1	-0.4	0.5	-0.4	-0.7	0.1	-1.0	0.6	-1.1	0.8
Alzheimer’s Disease (in mother)	0.5	0.6	2.7	0.3	0.5	0.3	-1.6	0.6	-0.5	0.6	0.4	0.6	0.6	1.5	0.4	0.8	-0.4	0.5	1.0	-0.4	1.3
Fasting Glucose	0.5	0.6	3.5	-0.3	-0.2	-0.4	0.0	-0.0	0.3	-0.6	-0.4	0.7	-0.7	-1.9	0.2	-0.7	-0.4	-1.3	-1.4	-1.0	-0.6
Triglycerides	0.5	0.9	7.4	0.4	-0.4	-0.9	-0.5	-0.6	0.2	-1.4	-0.4	-0.3	-0.4	-1.1	-0.9	-0.8	-2.7	-0.4	1.0	-0.5	-0.3
Blood Platelet Count	0.5	5.5	39.8	3.5	-0.9	-1.3	1.7	-1.3	0.3	-2.4	-0.9	-1.7	-0.9	-0.5	-1.6	-0.0	-0.8	0.1	-3.1	4.1	-6.3
Type 2 Diabetes (T2D) (2018)	0.5	0.9	4.6	0.2	-0.7	-0.8	1.2	-0.5	-0.8	-0.2	-0.6	-0.1	-0.7	-2.1	-0.6	0.2	-1.1	-1.6	-0.7	1.3	-1.2
Number of treatments/medications taken	0.5	0.9	5.7	0.9	-0.7	-0.8	-1.6	-0.5	0.4	-0.9	-0.6	-0.9	-0.5	1.5	-0.8	0.5	-2.4	-0.6	0.0	-0.5	-0.5
Ever used hormone-replacement therapy (HRT)	0.5	0.6	2.2	-1.1	-0.8	-0.4	-0.2	0.0	0.4	-0.2	-1.1	-1.0	-1.1	0.0	-0.6	-0.6	-0.7	-0.9	-0.7	-0.8	-1.5
Ever had hysterectomy (womb removed)	0.5	0.5	1.7	0.2	-0.7	-0.5	0.2	-1.0	-0.1	-1.1	-0.6	-0.9	-0.6	-0.1	-0.7	-1.2	-1.3	-0.0	0.4	-1.1	-0.6
Systolic blood pressure, automated reading	0.5	1.6	7.6	-0.5	-0.6	-0.7	-1.7	-0.8	-1.1	-1.7	-0.6	-1.3	-0.4	1.7	-0.8	-2.0	-2.8	-0.9	1.4	0.2	-0.3
Qualifications: None of the above	0.5	1.0	4.1	0.5	-0.7	-0.4	-0.3	-0.5	0.9	-1.3	-0.8	-1.3	-0.6	0.9	-0.5	-1.5	-2.0	-0.9	0.9	-1.7	0.4
Medication: Simvastatin	0.5	0.7	1.9	-0.0	-0.7	-1.2	-1.0	-0.2	0.2	-1.4	-0.9	-1.0	-0.8	0.4	-1.1	0.1	0.1	-1.2	1.0	1.4	-0.2
Forced expiratory volume in 1-second (FEV1)	0.5	1.6	3.7	-1.3	-1.5	-1.6	-1.2	-1.3	-1.5	-1.3	-1.5	0.1	-1.9	-1.3	-1.3	-0.8	-0.1	-1.2	0.8	0.9	-1.5
Qualifications: A levels/AS levels or equivalent	0.5	1.2	8.2	-2.1	-0.3	-0.6	0.2	-0.5	-0.5	1.0	-0.1	1.6	-0.4	-2.9	-0.9	0.8	0.1	0.3	-1.0	0.8	-0.9
Length of working week for main job	0.5	0.6	1.9	-0.5	-0.5	-0.9	0.1	-0.4	1.4	-0.2	-0.6	-0.4	-0.6	-0.9	-1.3	-0.6	0.1	-0.5	1.4	0.9	-0.3
Birth weight	0.5	1.1	6.7	-0.7	-1.4	-0.6	0.0	-0.7	-0.8	-0.2	-1.4	0.4	-1.4	-2.6	-0.7	0.3	1.0	-1.2	-0.8	-0.3	-0.9
Leg fat percentage (right)	0.5	1.7	7.3	-0.4	-1.4	-1.5	-0.6	-1.0	-1.1	-2.7	-1.7	-1.7	-1.3	0.2	-0.5	-1.9	0.3	-1.7	0.6	-0.2	-0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.6	2.8	-0.1	-0.6	0.0	-1.5	-0.8	0.5	-0.7	-0.5	0.3	-0.3	-0.6	0.2	-0.4	-0.9	-0.3	0.7	-1.7	1.2
Pulse wave peak to peak time	0.5	0.6	2.0	0.2	0.7	0.5	0.8	0.9	0.9	0.3	0.8	1.2	0.8	-0.0	0.8	-0.4	-0.3	-0.4	0.1	-1.2	1.4
Health satisfaction	0.5	0.6	3.3	1.1	-0.3	0.3	-1.2	-0.1	0.6	0.6	-0.2	-0.6	-0.1	0.4	0.4	0.5	-1.8	-0.5	-0.0	-1.4	0.8
Emphysema/chronic bronchitis	0.5	0.5	2.2	0.5	0.5	0.9	0.5	0.3	1.5	1.0	0.5	1.1	0.4	0.5	0.5	0.5	-0.6	0.2	-0.7	-1.3	0.3
Heart disease (mother)	0.5	0.7	5.2	0.1	-0.4	-0.5	0.1	-0.3	-0.6	-0.6	-0.4	-0.7	-0.5	-0.8	-0.5	-0.9	-2.3	-0.5	1.4	-0.8	0.3
Pulse rate, automated reading	0.5	1.7	15.0	-0.8	-0.8	-0.3	2.7	-0.8	1.0	0.3	-0.7	-0.5	-1.1	-3.9	-1.0	-0.1	-0.7	-0.9	-0.1	0.2	-0.5
Knee pain experienced in last month	0.5	0.7	3.1	1.7	0.0	-0.0	-0.7	0.7	-1.8	-0.5	-0.3	-0.1	-0.2	1.3	0.4	0.2	0.5	-0.7	0.9	-0.5	1.4
Whole body fat-free mass	0.5	3.1	20.4	0.2	-0.7	-0.6	4.0	0.5	-1.1	1.2	-1.1	2.4	-1.3	-4.5	0.3	0.9	2.0	-1.0	-0.5	-0.1	-0.1
Diabetes diagnosed by doctor	0.5	0.8	2.4	0.3	-0.7	-0.8	0.2	-0.4	-1.2	-0.5	-0.7	0.3	-0.9	-1.6	-0.6	0.0	-0.7	-1.5	-1.1	1.2	-1.4
Medication: Aspirin	0.5	0.6	2.0	1.1	0.2	0.2	-1.4	0.6	1.3	0.0	0.1	0.7	0.2	1.3	0.0	-0.4	-1.3	-0.4	0.3	-1.1	0.9
Whole body water mass	0.5	3.0	19.3	0.3	-0.7	-0.5	4.1	0.5	-1.0	1.2	-1.1	2.4	-1.3	-4.4	0.4	0.9	1.9	-0.9	-0.6	-0.2	-0.1
Number of self-reported non-cancer illnesses	0.5	0.9	3.0	0.3	-1.1	-1.0	-0.4	-1.1	0.8	-1.6	-1.0	-1.6	-1.0	0.4	-0.7	-0.7	-1.7	-0.8	0.3	-0.5	-0.7
Guilty feelings	0.5	0.7	3.1	0.1	-1.0	-0.8	-0.7	-1.1	-0.5	-1.1	-1.0	-0.4	-0.9	-0.6	-0.8	-1.8	0.2	-1.1	0.7	0.2	-0.2
Tinnitus: Yes, now most or all of the time	0.5	0.6	3.8	0.9	0.4	0.5	1.9	0.2	1.9	0.4	0.5	0.0	0.4	-0.5	0.4	0.6	0.0	1.1	-0.6	-0.1	-0.0
High cholesterol (Self-reported)	0.5	0.8	4.3	-0.4	-0.3	-0.8	-1.3	-0.4	1.4	-1.0	-0.4	-0.3	-0.2	-0.6	-0.8	0.6	-1.3	-0.2	1.0	2.1	-0.8
Basal metabolic rate	0.5	2.6	15.3	0.1	-0.9	-0.8	3.6	0.3	-1.3	0.8	-1.2	2.0	-1.4	-3.9	0.3	0.5	2.0	-1.2	-0.4	0.0	-0.2
Ever had prostate specific antigen (PSA) test	0.5	0.6	3.3	-1.3	-0.9	-0.3	-1.8	-0.7	-0.1	0.1	-0.8	1.1	-0.7	-0.9	-0.5	-0.5	-0.5	-0.9	0.1	0.2	0.1
Diastolic blood pressure, automated reading	0.5	1.5	8.5	1.5	1.0	0.4	1.7	0.9	0.5	0.3	0.8	0.2	0.9	2.9	0.5	-1.2	0.1	1.0	2.1	0.3	1.6
Unable to work because of sickness or disability	0.5	0.6	3.1	1.3	-0.7	-0.1	-0.9	-0.5	-0.5	-0.3	-0.7	-1.4	-0.7	0.4	0.0	-0.7	-0.0	-1.8	-0.8	-0.2	0.3
Supplements: Calcium	0.5	0.5	2.4	-1.0	0.0	-0.5	-1.5	-0.1	-1.5	-0.5	-0.0	-0.4	0.3	-0.6	0.3	0.6	-1.1	0.3	-0.4	0.2	-0.7
Alcohol drinker status: Previous	0.5	0.5	2.2	0.9	-0.8	-0.2	0.3	-0.5	0.6	-0.6	-0.9	-1.3	-0.8	0.0	-0.4	0.0	0.1	-0.2	-1.2	-0.5	-1.5
Worry (Nagel 2018)	0.4	0.8	3.6	0.2	-0.9	-0.7	-1.5	-0.7	1.9	-1.1	-0.9	-0.9	-1.0	0.3	-0.6	-1.4	0.1	-0.5	-0.2	-0.6	-0.6
HDL Cholesterol	0.4	0.6	4.6	-2.1	-0.3	-0.1	-1.5	-0.5	-0.3	0.4	-0.2	0.3	0.1	0.5	-0.2	-0.1	0.3	-0.1	-1.0	1.0	-0.7
Cardiovascular Disease	0.4	1.2	5.0	1.5	0.5	-0.0	-0.9	-0.2	-0.2	-0.8	0.7	-0.4	0.7	2.2	-0.2	-0.8	-1.7	0.5	1.8	1.8	1.3
Pack years adult smoking proportion	0.4	0.6	2.4	0.3	-0.2	-0.1	-0.0	-0.4	-1.4	-0.7	-0.2	-0.9	-0.3	-0.7	-0.3	-0.9	0.3	-0.3	1.5	1.2	1.3
Impedance of leg (right)	0.4	1.9	5.1	0.1	1.8	2.0	0.3	1.1	1.9	1.5	2.0	-0.0	2.3	1.3	1.6	0.8	-0.1	1.5	-0.1	-0.3	2.0
Townsend deprivation index at recruitment	0.4	0.6	1.9	1.0	0.8	0.9	-0.2	0.7	-1.4	0.6	0.7	1.1	0.7	1.3	0.5	-0.3	0.1	0.5	-0.9	0.3	0.1
Relative age voice broke	0.4	0.6	2.8	-0.8	0.0	0.3	-1.1	0.4	-1.6	0.2	-0.1	1.7	0.1	0.2	0.6	0.3	1.6	-0.2	-0.5	0.4	0.2
Medication: Atenolol	0.4	0.5	1.3	0.3	-0.7	-0.9	-0.8	-0.1	0.6	-0.7	-0.8	-0.6	-0.8	0.5	-1.1	-0.7	-0.6	-0.8	0.3	0.6	-0.7
Leg predicted mass (left)	0.4	1.9	9.7	0.6	-0.3	-0.4	3.1	0.8	-1.5	0.8	-0.7	2.3	-0.9	-2.7	0.8	0.4	2.0	-0.7	-0.5	-0.0	0.2
Had menopause	0.4	0.5	3.2	-1.8	-0.6	-0.3	0.4	-0.3	1.3	-0.3	-0.7	-0.1	-0.6	-1.0	-0.3	-0.3	0.0	0.4	0.0	-0.9	-0.9
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.9	5.3	1.1	-0.4	-0.2	-1.4	-0.2	-0.6	-0.7	-0.2	0.2	-0.3	-0.2	-0.9	0.6	-2.3	-0.6	-1.1	-1.6	-1.1
Diabetes (self-reported)	0.4	0.7	2.3	0.1	-0.8	-0.7	-0.2	-0.3	-1.3	-0.4	-0.8	0.5	-1.0	-1.3	-0.4	0.2	-0.4	-1.5	-1.1	0.8	-1.2
Hayfever/allergic rhinitis (self-reported)	0.4	0.6	2.4	0.8	-0.3	0.0	0.4	-0.2	0.4	0.1	-0.1	-1.1	-0.1	0.2	-0.1	0.6	-1.5	-0.4	-1.5	-1.1	-1.2
Hip circumference	0.4	1.8	4.5	-0.9	-1.7	-1.7	0.4	-0.9	-2.1	-1.3	-2.0	-0.3	-2.0	-0.9	-0.6	-1.6	1.6	-1.9	0.5	-0.2	-0.6
Worrier / anxious feelings	0.4	0.7	2.1	1.5	0.7	0.8	0.3	0.8	1.4	0.5	0.7	0.7	0.8	0.6	1.1	0.3	0.1	0.9	-0.2	-0.1	1.3
Pulse rate	0.4	0.7	5.4	0.3	-0.4	0.3	1.7	-0.2	1.2	0.5	-0.3	0.0	-0.4	-2.3	-0.7	0.5	0.1	0.0	-1.2	0.2	-0.3
Mouth/teeth dental problems: Dentures	0.4	0.6	1.9	-0.9	-0.7	-0.9	-0.9	-0.7	0.1	-0.7	-0.8	-1.1	-0.8	-0.6	-0.9	-1.0	-1.4	-0.4	-0.0	0.1	-0.7
Birth weight of first child	0.4	0.7	3.1	-0.5	-0.8	-1.0	1.8	-0.8	-0.4	-0.6	-0.8	1.0	-1.0	-1.5	-0.1	-0.3	-0.2	-0.3	0.7	0.3	-1.1
Chronic bronchitis/emphysema (mother)	0.4	0.4	1.3	0.4	-0.3	-0.5	-0.8	0.1	-0.9	-0.4	-0.3	-0.6	-0.3	0.8	-0.1	0.3	-1.0	-1.0	0.6	-1.1	0.6
Qualifications: College or University degree	0.4	1.4	4.5	-1.9	0.3	0.4	1.7	-0.0	-1.9	1.8	0.4	1.5	0.1	-1.7	0.1	0.2	2.1	0.5	-0.5	1.1	0.1
Mouth/teeth dental problems: Loose teeth	0.4	0.5	1.8	0.7	0.6	0.7	-0.3	0.8	-0.8	0.1	0.5	0.7	0.6	0.7	1.0	0.4	1.4	0.3	-0.7	0.3	0.7
Neck or shoulder pain in last month	0.4	0.6	2.7	0.7	0.0	-0.1	-0.9	0.1	0.6	-0.4	0.0	0.4	0.2	1.6	0.5	0.5	-0.2	-0.6	1.6	-0.6	1.4
Medication: Omeprazole	0.4	0.4	2.7	-0.2	-0.1	-0.5	0.3	-0.5	0.0	-0.6	-0.1	-0.7	-0.0	-0.5	-0.6	-0.2	-1.2	-0.2	0.9	1.6	-0.7
Had major operations	0.4	0.5	2.7	-0.7	-0.7	-0.4	0.9	-0.8	0.3	-0.6	-0.7	-1.1	-0.7	-0.3	-0.3	-1.6	-0.4	-0.2	0.1	-0.9	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	2.9	1.2	0.4	0.3	-0.9	0.2	0.1	0.2	0.5	0.3	0.7	0.7	0.5	0.3	0.5	0.1	-1.7	0.7	-0.7
Medication: Aspirin	0.4	0.5	2.6	0.9	-0.2	-0.4	-1.6	0.2	1.3	-0.4	-0.4	0.1	-0.3	0.8	-0.5	-0.6	-1.1	-0.8	0.3	-0.8	0.3
Smoking status: Previous	0.4	0.6	2.5	1.0	0.2	0.8	-0.5	0.8	0.4	1.0	0.1	0.7	-0.0	1.6	1.0	0.3	-0.4	-0.6	-0.4	-1.4	0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.8	3.5	-0.7	0.1	0.1	0.6	0.5	-0.4	1.3	0.1	1.9	-0.2	-1.9	0.4	0.1	1.2	-0.5	1.1	0.3	1.3
Qualifications: nursing, teaching	0.4	0.6	5.2	-0.6	-0.1	0.3	0.8	0.2	0.5	1.2	-0.1	1.0	-0.4	-0.3	0.3	0.5	2.3	0.2	-0.9	0.7	-0.5
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	3.8	0.2	0.2	-0.6	0.4	-0.2	0.1	-0.7	0.1	-0.7	0.3	-0.2	-0.4	0.1	-0.8	0.5	1.0	1.9	-0.8
Pack years of smoking	0.4	0.6	2.5	0.2	-0.3	-0.2	-0.1	-0.5	-1.4	-0.7	-0.2	-0.9	-0.4	-0.6	-0.5	-0.8	0.1	-0.2	1.6	1.4	1.0
Leg fat mass (left)	0.4	1.7	4.2	-0.4	-1.7	-1.7	0.4	-0.8	-1.6	-2.0	-2.0	-1.0	-1.8	-0.8	-0.5	-1.6	1.1	-2.0	0.5	-0.1	-0.8
Alzheimer’s Disease (including proxy)	0.3	0.5	2.0	1.0	0.9	0.3	-0.1	0.6	0.3	0.1	0.7	0.1	0.8	1.4	0.8	0.7	-0.6	1.0	0.4	-0.4	0.3
Ulcerative Colitis (UC)	0.3	0.5	2.6	0.5	-0.1	0.2	0.2	-0.1	-0.7	-0.3	-0.2	-0.8	-0.3	1.0	-0.4	-0.2	1.6	-0.8	-1.6	-0.0	-0.3
LDL Cholesterol	0.3	0.5	1.9	-0.6	-0.7	-0.4	-1.1	-0.3	-0.4	-0.7	-0.8	-0.1	-0.5	0.2	-0.1	-0.3	-1.2	-1.4	0.2	-1.0	-0.7
Lupus	0.3	0.5	1.5	0.4	-0.6	-0.4	-1.0	-0.7	-0.8	-0.7	-0.6	-0.9	-0.4	1.0	0.4	-0.8	-0.0	-0.9	-0.2	-1.2	0.2
Rheumatoid Arthritis	0.3	0.4	1.4	-0.9	-0.6	-0.7	-0.2	-0.2	0.1	-1.2	-0.8	-0.7	-0.6	-0.4	-0.3	-0.5	0.8	-0.6	1.1	-0.6	0.2
Ulcerative Colitis	0.3	0.5	1.5	1.2	0.9	0.4	1.2	0.8	-0.8	0.3	0.7	-0.5	0.0	1.1	-0.1	0.9	0.0	0.5	0.1	-0.0	0.9
Neuroticism	0.3	0.7	3.0	1.5	-0.8	-0.7	-0.7	-0.6	1.7	-1.2	-0.7	-0.4	-0.6	-1.1	-0.4	-1.0	-0.6	-0.7	-0.3	-0.7	-0.2
Relative age of first facial hair	0.3	0.6	4.2	-1.4	-0.4	-0.7	-0.1	-0.8	-2.0	-0.6	-0.2	0.2	-0.0	0.2	-0.1	-0.9	-0.2	-0.1	0.3	0.9	-0.4
Supplements: Zinc	0.3	0.3	0.9	0.2	0.4	0.3	-0.8	0.8	0.4	0.2	0.3	0.3	0.3	0.8	0.7	0.7	0.0	0.1	-0.5	-0.9	0.7
Medication: Metformin	0.3	0.4	1.2	0.7	-0.1	-0.3	1.0	0.1	-0.6	0.3	-0.1	0.3	-0.3	-0.2	-0.1	0.7	-0.2	-0.6	-1.0	1.1	-1.1
Severe depression (siblings)	0.3	0.3	1.1	0.8	-0.0	-0.2	-0.8	0.3	0.6	-0.7	-0.2	0.4	-0.0	0.7	0.1	0.5	1.1	-0.3	-0.8	0.6	-0.6
Leg fat-free mass (left)	0.3	1.8	9.7	0.6	-0.3	-0.4	3.1	0.8	-1.5	0.8	-0.6	2.3	-0.9	-2.7	0.8	0.5	2.0	-0.7	-0.5	-0.0	0.2
Fed-up feelings	0.3	0.5	2.1	1.4	-0.1	-0.3	0.4	0.3	-0.1	-1.0	-0.3	0.3	-0.2	-1.1	0.5	-0.8	0.3	-0.7	-1.1	0.8	-0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	2.8	0.9	-0.3	0.0	-1.6	0.1	-0.5	-0.1	-0.1	0.5	0.0	-0.1	-0.7	0.4	-1.4	-0.7	-1.7	-1.5	-1.0
Serious illness, injury or assault to yourself	0.3	0.3	1.8	1.1	0.3	0.3	1.0	0.4	-0.3	0.2	0.2	0.2	0.0	-0.2	0.6	0.2	1.4	0.4	-0.4	0.7	-0.3
Multivitamins +/- minerals	0.3	0.4	2.8	0.1	-0.6	-0.7	1.0	-0.3	1.7	-0.5	-0.7	-0.6	-0.8	-0.0	0.4	-0.4	0.2	-0.4	0.4	-0.6	-0.1
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	2.5	-0.5	-0.2	-0.0	-0.2	0.1	-0.5	-0.5	-0.3	-0.2	-0.3	-1.2	-0.2	0.2	1.6	-0.3	-0.5	-0.2	0.4
Nervous feelings	0.3	0.6	3.1	0.5	-0.5	0.3	-0.6	-0.8	1.8	-0.3	-0.4	-0.5	-0.4	0.5	0.2	-0.9	-1.5	0.1	-0.8	-1.3	-0.7
Heart attack	0.3	0.4	1.7	0.1	0.2	0.3	0.1	0.9	1.2	0.5	-0.1	0.0	0.2	0.5	0.5	0.4	-0.0	-0.6	0.6	-1.1	1.3
Weight	0.3	1.4	5.5	-0.3	-1.1	-1.1	2.3	0.0	-1.7	-0.3	-1.4	0.9	-1.4	-2.1	0.2	-0.6	1.6	-1.5	0.1	-0.1	-0.3
Arm fat percentage (right)	0.3	1.0	3.9	0.3	-0.6	-0.6	-0.1	0.1	-2.0	-1.7	-0.8	-0.6	-0.6	1.8	0.8	-1.4	1.2	-1.2	0.8	-0.5	0.5
Prospective memory result	0.3	0.4	2.1	1.5	0.1	-0.0	-0.4	-0.2	0.5	-1.1	-0.0	-1.1	0.3	1.1	-0.0	0.1	-0.2	-0.4	-0.7	0.1	-0.0
Illnesses of mother	0.3	0.4	1.6	-1.1	-0.1	0.3	0.6	0.0	0.1	0.2	-0.1	1.1	-0.2	-1.1	0.3	-0.2	1.3	0.2	-0.9	-0.1	-0.5
Pulse wave Arterial Stiffness index	0.3	0.3	1.2	0.1	-0.4	-0.2	-0.0	-0.5	-0.7	0.2	-0.5	-0.8	-0.6	-0.3	-0.4	0.7	0.5	0.7	-0.1	1.1	-1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	2.8	-0.4	-0.6	-0.3	-0.8	-0.2	1.7	-0.7	-0.7	0.8	-0.6	0.3	0.5	-0.7	0.0	-0.6	-0.2	-0.8	-0.2
Peak expiratory flow (PEF)	0.3	0.8	3.4	-0.8	-0.7	-0.8	-1.5	-0.9	-1.9	-0.4	-0.6	0.2	-0.8	-0.0	-0.5	0.3	-0.3	-0.8	1.7	0.8	0.1
Medication: Paracetamol	0.3	0.5	1.7	0.5	-0.4	-0.9	0.2	-0.8	0.1	-1.2	-0.3	-1.0	-0.6	1.3	-0.4	0.4	-1.1	0.4	1.0	-0.0	-0.8
Body fat percentage	0.3	1.1	3.5	-0.2	-0.7	-0.8	-0.4	-0.1	-1.7	-1.9	-1.0	-1.1	-0.7	1.7	0.6	-1.5	1.1	-1.3	0.8	-0.1	0.2
Wheeze or whistling in the chest in last year	0.3	0.5	3.6	-0.3	-0.1	0.6	0.3	0.0	1.1	0.6	0.0	1.3	0.0	-0.1	0.5	-0.9	-0.5	0.1	-0.6	-1.9	0.5
Shortness of breath walking on level ground	0.3	0.4	1.9	0.4	-0.7	-0.5	-1.0	-0.2	0.2	0.3	-0.6	-0.5	-0.4	-0.1	-0.5	0.0	-1.4	-1.1	-0.0	-0.9	-0.1
Medication for pain relief, constipation, heartburn	0.3	0.5	2.6	-1.6	-0.1	0.8	0.6	0.1	-0.2	0.5	-0.1	0.2	0.1	-1.3	0.7	-0.9	1.2	-0.1	-0.7	-0.4	0.1
Medication: Blood pressure	0.3	0.5	3.4	0.6	-0.2	0.3	-0.1	0.0	0.7	0.4	-0.1	-0.6	0.2	1.8	-0.4	-0.4	0.4	-0.2	0.3	-0.7	1.8
Medication: Ibuprofen	0.3	0.4	1.8	1.1	0.5	-0.2	0.5	0.7	0.3	0.3	0.3	1.0	0.3	0.3	-0.2	1.4	-0.2	0.2	0.4	0.9	0.1
Leg fat mass (right)	0.3	1.2	3.1	0.0	-1.3	-1.3	0.8	-0.4	-1.4	-1.8	-1.6	-0.7	-1.4	-0.7	-0.1	-1.3	1.2	-1.7	0.4	-0.1	-0.5
Overall health rating	0.3	0.6	3.8	1.9	-0.5	0.4	0.5	-0.2	-0.1	0.2	-0.5	-1.3	-0.5	0.6	0.4	-0.6	-1.2	-1.1	-0.1	-1.1	0.5
Chest pain or discomfort	0.3	0.4	2.0	-0.9	-0.3	0.1	-0.1	-0.2	0.6	-0.1	-0.3	1.0	-0.1	-0.8	0.5	-0.0	-1.4	-0.2	0.3	-1.1	-1.0
Leg fat-free mass (right)	0.3	1.8	9.4	0.2	-0.7	-0.8	2.9	0.5	-1.5	0.7	-1.0	2.0	-1.2	-3.1	0.3	0.3	1.7	-1.0	-0.4	0.5	-0.2
Arm fat percentage (left)	0.3	1.3	5.0	-0.1	-0.7	-0.8	-0.8	-0.1	-2.2	-2.0	-1.0	-0.8	-0.8	2.0	0.7	-1.7	0.9	-1.3	0.9	-0.3	0.2
Loneliness, isolation	0.3	0.5	2.2	0.9	0.0	0.5	-0.1	0.1	0.1	-0.2	0.0	0.7	0.3	-0.7	1.0	0.1	0.8	-0.2	-0.9	-1.5	1.3
Back pain experienced in last month	0.3	0.4	3.0	0.2	-0.0	-0.1	0.5	-0.1	-1.7	0.1	-0.0	1.0	-0.1	-0.0	-0.1	1.0	-0.3	0.0	1.2	-0.4	0.9
Medication: Gliclazide	0.3	0.3	2.1	0.2	-0.3	-0.4	-0.8	-0.3	0.3	-0.3	-0.2	-0.1	0.1	1.0	-0.6	-0.4	-1.5	-0.1	-0.4	-0.3	-0.4
Leg predicted mass (right)	0.3	1.9	9.2	0.3	-0.6	-0.7	3.0	0.6	-1.6	0.8	-0.9	2.0	-1.1	-2.9	0.4	0.3	1.9	-0.9	-0.4	0.5	-0.1
Arm fat mass (left)	0.3	1.1	4.5	-0.3	-1.1	-1.0	0.5	-0.3	-2.1	-1.4	-1.4	-0.1	-1.3	-0.1	0.3	-1.3	1.4	-1.6	0.5	-0.3	-0.1
Medication: Paracetamol	0.3	0.5	2.1	0.1	-0.2	-0.8	0.6	-0.7	0.7	-0.9	-0.1	-0.6	-0.3	1.1	-0.4	0.4	-1.2	0.8	1.4	0.2	-0.5
Medication: Atorvastatin	0.3	0.4	1.3	0.7	0.6	1.1	0.6	0.7	0.2	0.9	0.6	0.7	0.8	-0.1	0.6	0.5	0.2	0.4	-0.8	-0.3	-0.0
Illnesses of father: High blood pressure	0.3	0.4	3.5	0.9	-0.1	-0.4	-0.5	0.0	-0.1	-0.7	-0.1	-1.1	-0.1	1.9	0.1	-0.4	-0.8	-0.1	0.2	-0.5	-0.3
Irritability	0.3	0.4	3.1	0.6	-0.4	-0.2	-0.1	-0.1	0.3	-0.4	-0.4	0.8	-0.4	-1.8	-0.5	-0.5	0.3	-0.8	-1.2	-0.6	-0.1
Risk taking	0.3	0.4	2.2	-0.2	0.1	-0.1	-0.8	0.2	-0.7	-0.2	0.0	-0.1	0.2	1.2	-0.2	-0.5	0.2	-0.3	1.5	1.0	0.6
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.6	-0.1	-0.1	0.2	-0.2	0.7	1.3	0.3	-0.3	-0.2	0.0	0.5	0.2	0.2	-0.3	-0.8	0.6	-1.2	1.1
Bipolar Disorder (2018)	0.2	0.3	3.1	-0.3	-0.0	0.2	-0.9	-0.1	-1.8	-0.1	-0.0	0.6	-0.1	-0.4	-0.1	0.5	-0.5	0.2	-0.1	-0.6	-0.4
Depressed Affect (Nagel 2018)	0.2	0.4	3.1	1.8	0.0	0.1	-0.4	0.3	1.0	-0.6	-0.1	0.6	-0.1	-0.4	0.2	-0.5	-0.1	-0.3	-0.3	-0.6	0.8
Neuroticism (Nagel 2018)	0.2	0.4	1.7	1.1	-0.2	-0.2	-0.9	-0.1	1.3	-0.9	-0.3	0.2	-0.3	-0.0	-0.1	-1.2	0.4	-0.5	0.2	-0.2	0.4
Alzheimer’s Disease (in father)	0.2	0.3	1.0	0.8	0.4	0.0	1.0	0.6	0.8	0.1	0.3	0.1	0.2	0.1	0.6	0.7	0.0	0.8	-0.3	-0.4	-0.6
Age at First Birth	0.2	0.3	0.8	-0.5	0.1	0.4	-0.4	0.2	-0.8	0.9	0.2	0.6	0.2	0.3	0.1	0.4	-0.9	-0.5	-0.1	-0.9	0.8
Neuroticism (2016)	0.2	0.3	1.3	1.1	-0.1	-0.2	-0.2	-0.3	-0.0	-0.8	-0.0	0.0	-0.1	1.0	0.5	-0.5	0.4	0.2	0.8	-0.5	0.8
Respiratory disease	0.2	0.5	3.5	0.3	0.3	0.1	1.3	0.2	1.9	1.4	0.5	0.4	0.6	-0.5	-0.2	0.3	-0.1	0.6	-0.2	-0.4	0.3
Tanning	0.2	2.5	6.2	2.4	1.7	1.9	1.2	1.7	-1.1	2.1	1.7	1.2	1.4	2.5	1.4	1.5	1.3	1.2	-1.3	0.4	1.2
Hand grip strength (left)	0.2	0.6	2.5	-0.3	-0.4	0.0	0.1	-0.5	1.3	0.7	-0.2	0.5	-0.5	-1.4	0.3	0.6	-0.7	-0.5	-1.6	-1.5	-0.6
Angina	0.2	0.2	1.0	0.4	-0.4	-0.1	-0.8	-0.3	0.4	0.0	-0.4	-0.4	-0.4	0.3	-0.2	-0.1	-0.8	-0.8	-0.4	-1.0	0.2
Medication for hormone replacement therapy	0.2	0.2	1.0	-0.6	0.1	-0.0	-0.4	0.7	0.1	0.4	0.0	0.6	0.0	0.2	0.4	0.2	0.8	-0.5	0.3	-0.8	1.0
Vitamin and mineral supplements	0.2	0.3	3.3	-0.1	0.1	0.0	-1.0	-0.2	-1.8	-0.1	0.2	0.0	0.2	-0.4	-0.6	-0.1	-0.3	-0.4	0.5	0.1	0.6
Diabetes (father)	0.2	0.3	1.2	0.4	-0.1	0.3	-0.3	0.5	-0.3	0.3	-0.2	-0.8	-0.2	0.1	-0.1	0.6	-1.1	-0.6	-0.3	-0.8	-0.7
Trunk fat percentage	0.2	0.9	3.9	-0.1	-0.3	-0.3	-0.0	0.4	-1.7	-1.3	-0.5	-0.6	-0.3	2.0	1.0	-1.2	1.1	-1.0	0.9	-0.3	0.8
Impedance of leg (left)	0.2	0.8	3.1	-0.8	1.0	1.2	-0.2	0.4	1.8	1.0	1.1	-0.9	1.4	0.7	0.5	0.2	-0.3	0.7	0.2	0.3	1.3
Trunk fat mass	0.2	0.7	2.9	0.3	-0.2	-0.2	1.5	0.7	-1.5	-0.5	-0.5	0.2	-0.4	0.7	1.2	-0.7	1.7	-0.9	0.5	-0.2	1.0
Waist circumference	0.2	0.6	3.2	1.2	-0.5	-0.4	1.8	0.4	-0.9	-0.3	-0.8	0.0	-0.7	-0.5	0.6	-0.2	1.0	-0.9	-0.3	-0.9	0.1
Medication: Ramipril	0.2	0.3	0.9	-0.0	-0.3	-0.5	-0.5	0.2	-0.9	-0.5	-0.5	-0.8	-0.4	1.0	-0.3	-0.3	-0.6	-0.8	0.4	-0.1	0.4
Time employed in main current job	0.2	0.3	0.9	-0.1	-0.4	0.2	0.7	-0.7	0.3	0.3	-0.2	-0.3	-0.2	-0.4	-0.7	-0.5	0.6	0.6	-0.9	-0.2	-0.9
Father’s age at death	0.2	0.3	2.0	-0.2	-0.3	-0.0	0.5	-0.5	0.2	0.6	-0.3	0.2	-0.4	-1.4	0.1	-0.3	0.6	0.4	-0.1	-0.3	-0.9
Asthma	0.2	0.4	0.7	-0.6	-0.7	-0.8	0.7	-0.7	0.7	-0.3	-0.6	-0.5	-0.5	-0.6	-0.7	-0.2	-0.6	-0.7	0.3	0.2	-0.8
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	0.8	0.9	-0.2	-0.6	-0.5	0.1	-0.1	-0.1	-0.3	-0.0	-0.2	0.3	-0.9	0.8	-0.5	-0.6	0.2	0.7	-0.6
Arm fat mass (right)	0.2	0.8	3.3	0.2	-0.9	-0.8	1.0	-0.1	-1.8	-1.2	-1.2	-0.1	-1.1	0.0	0.5	-1.1	1.4	-1.3	0.5	-0.4	0.1
Headache pain in last month	0.2	0.3	2.2	1.5	0.1	-0.4	-0.3	-0.0	0.5	-1.0	0.1	0.1	0.2	0.7	-0.2	0.6	-1.1	-0.0	0.2	0.1	-0.6
Medication: Ventolin 100micrograms inhaler	0.2	0.3	1.8	0.1	0.3	-0.0	0.4	-0.1	-0.3	0.3	0.3	0.2	0.5	0.4	0.0	0.2	-1.3	0.1	-0.5	0.8	-0.9
Forced vital capacity (FVC), Best measure	0.2	0.6	2.3	-0.8	-0.8	-0.9	-1.5	-0.7	-1.0	-0.2	-0.8	1.2	-1.1	-0.2	-0.8	-0.3	0.4	-0.7	0.6	0.1	-0.4
Whole body fat mass	0.2	0.7	2.4	0.1	-0.7	-0.6	1.0	0.3	-1.4	-1.0	-1.0	-0.1	-0.9	0.2	0.7	-0.9	1.5	-1.2	0.3	-0.3	0.3
Number of full sisters	0.2	0.2	1.6	0.6	0.1	0.2	-0.4	0.3	-0.2	-0.1	0.1	-0.1	0.1	-0.2	-0.3	0.2	-1.3	0.1	-0.8	-1.0	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	0.8	0.1	-0.1	-0.2	0.0	-0.3	0.9	-0.6	-0.2	-0.1	0.0	-0.2	-0.1	0.6	-0.3	-0.5	-0.5	0.6	-0.7
Asthma (self-reported)	0.2	0.3	0.9	-0.5	-0.6	-0.8	0.8	-0.6	0.5	-0.2	-0.6	-0.4	-0.4	-0.5	-0.7	-0.2	-0.4	-0.6	0.2	0.3	-0.9
Average weekly champagne plus white wine intake	0.2	0.2	0.7	-0.2	0.1	0.1	0.5	-0.4	0.7	0.8	0.4	0.3	0.3	0.6	-0.4	0.4	-0.6	0.3	-0.2	0.8	-0.2
Pain experienced in last month	0.2	0.4	1.8	-0.6	-0.1	-0.2	0.7	-0.4	1.1	-0.2	-0.1	-1.0	-0.2	-1.3	-0.5	-0.6	0.5	0.1	-0.1	0.8	-0.7
Crohns Disease (2017)	0.1	0.3	1.0	1.0	0.2	0.1	1.0	0.1	0.8	0.1	0.2	-0.3	0.2	-0.6	-0.5	-0.8	-0.3	-0.5	0.8	0.3	0.6
Irritable Bowel Disease (IBD)	0.1	0.2	0.8	0.7	-0.1	0.1	0.6	-0.2	-0.2	-0.3	-0.2	-0.7	-0.2	0.3	-0.7	-0.7	0.8	-0.9	-0.4	-0.0	0.0
Crohns Disease (2012)	0.1	0.2	1.0	0.3	-0.1	-0.3	0.3	-0.3	0.9	-0.0	-0.0	-0.6	0.0	-0.4	-0.4	-0.8	0.0	-0.3	1.0	0.7	0.2
Sensitivity / hurt feelings	0.1	0.2	0.9	0.4	-0.0	-0.5	-0.2	0.1	0.3	-0.5	-0.2	-0.5	-0.2	-0.0	-0.1	-0.1	0.9	-0.6	-1.0	0.8	-0.1
Forced vital capacity (FVC)	0.1	0.5	1.8	-0.9	-0.7	-0.7	-0.6	-0.6	-0.6	-0.2	-0.7	1.3	-1.1	-0.5	-0.5	-0.2	0.2	-0.7	1.1	0.6	-0.3
Hair/balding pattern: Pattern 3	0.1	0.2	0.8	0.5	-0.0	0.0	0.2	-0.6	-0.2	0.2	0.2	-0.5	0.3	-0.3	-0.8	-0.1	-0.9	0.3	0.4	0.1	0.3
Loud music exposure frequency	0.1	0.1	0.9	-0.5	-0.2	-0.1	0.2	-0.2	0.2	-0.5	-0.2	-0.3	-0.0	0.2	0.2	-0.2	-0.0	-0.5	0.6	-0.9	0.3
Angina (self-reported)	0.1	0.2	1.0	0.4	-0.2	0.2	-0.5	-0.0	0.3	0.3	-0.1	-0.1	-0.1	0.5	0.1	0.2	-0.5	-0.5	-0.2	-1.0	0.6
Illnesses of father: Heart disease	0.1	0.1	0.3	-0.1	-0.1	-0.1	-0.5	0.2	0.2	-0.5	-0.2	0.5	-0.2	-0.0	-0.1	0.5	0.3	-0.3	0.1	-0.5	0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.9	1.0	0.2	-0.1	-0.3	-0.2	-0.2	0.4	0.3	0.2	0.4	-0.4	-0.4	0.2	-0.3	0.5	-0.0	0.3	0.2
Hearing aid user	0.1	0.1	0.6	-0.1	0.1	-0.1	-0.7	0.2	-0.5	-0.1	0.1	0.1	0.5	-0.6	-0.3	0.2	-0.0	0.0	0.6	-0.5	0.7
Bipolar Disorder (2011)	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.6	0.5	0.0	-0.3
Hair Pigment	0.0	0.6	2.0	-0.8	-0.4	0.0	-0.5	-0.2	0.7	1.2	-0.5	-1.1	-0.4	0.9	-1.2	-1.1	-0.4	-0.2	-1.2	-0.3	-1.4

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