[Hub]/) : Traits : Impedance of arm (left) :

chr12:49,780,778-51,912,062

Best TWAS P=1.71e-10 · Best GWAS P=6.66e-10 conditioned to 2.15e-07

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DIP2B 0.11 0.10 enet 16 0.13 2.6e-15 6.1 6.4 1.7e-10 0.07 0.01 0.99 TRUE
2 GTEx Brain Putamen basal ganglia CERS5 0.29 0.12 enet 36 0.21 1.2e-05 5.3 5.3 9.2e-08 -0.01 0.35 0.32 FALSE
3 GTEx Breast Mammary Tissue (Female) CERS5 0.09 0.03 lasso 3 0.05 1.8e-02 -3.8 6.2 6.1e-10 -0.53 0.06 0.13 TRUE
4 GTEx Heart Atrial Appendage CERS5 0.14 0.03 lasso 6 0.02 4.2e-02 5.4 5.3 1.1e-07 -0.02 0.36 0.38 FALSE
5 GTEx Nerve Tibial CERS5 0.31 0.28 enet 20 0.36 2.2e-26 5.4 5.4 5.4e-08 0.01 0.30 0.70 FALSE
6 GTEx Prostate CERS5 0.19 0.08 lasso 4 0.02 1.2e-01 5.2 5.5 4.0e-08 0.01 0.07 0.25 FALSE
7 GTEx Testis SMARCD1 0.22 0.10 enet 22 0.10 2.6e-05 5.4 -5.3 1.1e-07 0.09 0.22 0.70 FALSE
8 GTEx Testis CERS5 0.12 0.06 lasso 6 0.07 4.0e-04 5.4 5.6 1.9e-08 0.02 0.10 0.53 FALSE
9 GTEx Whole Blood RP4-605O3.4 0.04 0.04 lasso 4 0.01 1.5e-02 5.2 5.3 1.1e-07 0.00 0.12 0.60 FALSE
10 NTR Blood ATF1 0.06 0.07 enet 35 0.07 4.0e-21 6.0 5.2 1.9e-07 0.05 0.01 0.99 FALSE
11 YFS Blood ATF1 0.05 0.07 lasso 9 0.07 2.0e-21 5.9 6.3 3.4e-10 0.04 0.02 0.98 FALSE
12 YFS Blood DIP2B 0.36 0.27 bslmm 385 0.28 2.8e-90 -4.6 5.2 2.1e-07 0.01 0.97 0.03 FALSE
13 YFS Blood LIMA1 0.04 0.06 enet 31 0.06 3.5e-19 -4.1 -5.6 2.3e-08 0.04 1.00 0.00 FALSE
14 The Cancer Genome Atlas Breast Invasive Carcinoma SMARCD1 0.02 0.03 lasso 1 0.03 3.7e-06 5.3 -5.3 1.4e-07 0.02 0.02 0.98 FALSE
15 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma LIMA1 0.08 0.10 blup 59 0.10 1.8e-11 5.5 -5.6 1.8e-08 -0.02 0.02 0.98 FALSE
16 The Cancer Genome Atlas Brain Lower Grade Glioma ATF1 0.03 0.04 lasso 1 0.04 6.3e-05 5.9 -5.9 4.5e-09 -0.04 0.01 0.98 FALSE
17 The Cancer Genome Atlas Lung Adenocarcinoma DIP2B 0.09 0.02 enet 9 0.05 1.3e-06 -4.7 -5.5 4.3e-08 -0.04 0.20 0.61 FALSE