[Hub]/) : Traits : Impedance of arm (left) : ← →

chr22:37,781,874-39,355,109

Best TWAS P=2.89e-16 · Best GWAS P=8.42e-16 conditioned to 0.0128

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous BAIAP2L2 0.11 0.03 lasso 5 0.04 1.8e-04 5.6 -7.6 3.8e-14 -0.72 0.05 0.79 FALSE
2 GTEx Artery Aorta TMEM184B 0.17 0.07 enet 34 0.03 1.2e-02 6.9 -6.5 7.9e-11 -0.68 0.04 0.79 FALSE
3 GTEx Artery Aorta AL021977.1 0.13 0.00 enet 17 0.01 8.7e-02 7.8 -6.7 1.7e-11 -0.72 0.02 0.84 FALSE
4 GTEx Brain Cortex TMEM184B 0.29 0.12 lasso 7 0.09 1.6e-03 6.9 -6.7 2.9e-11 -0.83 0.02 0.85 FALSE
5 GTEx Cells EBV-transformed lymphocytes PLA2G6 0.28 0.17 enet 13 0.18 1.3e-06 -5.5 6.5 6.4e-11 0.76 0.06 0.90 FALSE
6 GTEx Cells Transformed fibroblasts PLA2G6 0.23 0.09 lasso 9 0.10 9.9e-08 5.6 6.4 1.2e-10 0.92 0.07 0.93 FALSE
7 GTEx Esophagus Gastroesophageal Junction PLA2G6 0.28 0.24 lasso 5 0.23 1.1e-08 -5.5 5.9 4.4e-09 0.76 0.20 0.77 FALSE
8 GTEx Esophagus Mucosa PLA2G6 0.22 0.02 lasso 6 0.04 1.9e-03 5.6 6.0 1.6e-09 0.84 0.06 0.92 FALSE
9 GTEx Nerve Tibial PLA2G6 0.34 0.08 lasso 8 0.11 2.9e-08 -5.5 6.4 2.1e-10 0.86 0.03 0.97 FALSE
10 GTEx Nerve Tibial MAFF 0.14 0.06 lasso 3 0.05 1.2e-04 8.0 -7.8 7.1e-15 -0.88 0.01 0.99 FALSE
11 GTEx Skin Sun Exposed Lower leg BAIAP2L2 0.09 0.09 lasso 4 0.09 5.5e-08 5.0 -5.1 2.8e-07 -0.78 0.28 0.72 FALSE
12 GTEx Thyroid PLA2G6 0.34 0.20 lasso 5 0.18 4.5e-14 -5.5 6.2 5.9e-10 0.82 0.68 0.32 FALSE
13 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PLA2G6 0.05 0.01 blup 76 0.01 7.7e-02 6.9 8.2 2.9e-16 0.80 0.02 0.73 TRUE
14 The Cancer Genome Atlas Thyroid Carcinoma PLA2G6 0.03 0.02 lasso 2 0.03 6.5e-04 6.8 6.7 1.9e-11 0.96 0.05 0.52 FALSE