[Hub]/) : Traits : Impedance of arm (left) : ← →

chr22:28,478,985-32,995,751

Best TWAS P=2.03e-10 · Best GWAS P=3.39e-10 conditioned to 0.00636

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
11	NTR	Blood	DEPDC5	0.02	0.02	lasso	5	0.01	2.4e-05	-6.1	6.4	2.0e-10	-0.60	0.01	0.99	TRUE
2	GTEx	Adipose Subcutaneous	KREMEN1	0.19	0.13	enet	22	0.13	9.2e-11	5.0	5.9	3.2e-09	0.05	0.19	0.81	TRUE
1	CommonMind	Brain Pre-frontal Cortex	RNF215	0.03	0.00	blup	442	0.00	1.9e-01	-3.0	-5.2	2.0e-07	0.12	0.01	0.12	TRUE
20	The Cancer Genome Atlas	Thyroid Carcinoma	RNF185	0.06	0.09	lasso	4	0.07	1.5e-07	-6.3	-6.2	5.8e-10	1.00	0.00	1.00	FALSE
4	GTEx	Esophagus Gastroesophageal Junction	SFI1	0.15	0.07	lasso	3	0.06	3.7e-03	-5.5	6.1	8.4e-10	-0.93	0.04	0.82	FALSE
7	GTEx	Muscle Skeletal	SFI1	0.13	0.09	enet	22	0.10	1.7e-10	4.7	5.9	3.3e-09	-0.70	0.44	0.56	FALSE
19	The Cancer Genome Atlas	Rectum Adenocarcinoma	RNF185	0.18	0.10	enet	6	0.12	9.7e-04	-6.1	-5.7	9.1e-09	0.95	0.00	0.88	FALSE
10	GTEx	Skin Sun Exposed Lower leg	CCDC117	0.07	0.03	enet	11	0.03	2.8e-03	3.2	-5.7	1.2e-08	-0.03	0.12	0.46	FALSE
17	The Cancer Genome Atlas	Brain Lower Grade Glioma	LIMK2	0.06	0.06	blup	47	0.06	9.3e-08	-4.7	5.6	2.8e-08	-0.91	0.07	0.93	FALSE
14	YFS	Blood	PISD	0.36	0.32	lasso	9	0.35	5.1e-122	-6.1	5.5	2.9e-08	-0.64	0.01	0.99	FALSE
16	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	KREMEN1	0.13	0.10	lasso	5	0.11	3.3e-12	4.6	5.4	5.7e-08	0.01	0.66	0.33	FALSE
5	GTEx	Esophagus Muscularis	LIMK2	0.08	0.03	lasso	4	0.01	4.3e-02	-5.5	5.4	6.4e-08	-0.84	0.05	0.85	FALSE
3	GTEx	Breast Mammary Tissue	KREMEN1	0.14	0.06	enet	10	0.10	6.9e-06	4.4	5.4	7.8e-08	0.07	0.26	0.62	FALSE
15	The Cancer Genome Atlas	Colon Adenocarcinoma	RNF185	0.08	0.05	blup	54	0.08	1.8e-05	-6.3	-5.4	7.8e-08	0.85	0.01	0.99	FALSE
12	NTR	Blood	PISD	0.05	0.08	lasso	5	0.09	3.3e-27	-6.1	5.3	9.1e-08	-0.52	0.02	0.98	FALSE
8	GTEx	Nerve Tibial	SFI1	0.23	0.06	enet	16	0.14	1.9e-10	-4.7	5.3	9.3e-08	-0.75	0.33	0.67	FALSE
9	GTEx	Pancreas	KREMEN1	0.33	0.24	lasso	7	0.23	4.2e-10	5.0	5.3	1.5e-07	0.03	0.18	0.82	FALSE
18	The Cancer Genome Atlas	Prostate Adenocarcinoma	RNF185	0.06	0.05	blup	54	0.05	4.7e-06	-6.1	-5.2	1.6e-07	0.82	0.00	0.99	FALSE
13	YFS	Blood	EIF4ENIF1	0.01	0.00	blup	362	0.01	9.7e-04	6.2	5.2	2.3e-07	-0.47	0.02	0.64	FALSE
6	GTEx	Heart Left Ventricle	SFI1	0.12	0.10	enet	20	0.07	2.3e-04	4.7	5.1	2.9e-07	-0.67	0.06	0.93	FALSE