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chr17:27,200,734-29,313,078

Best TWAS P=6.65e-13 · Best GWAS P=4.39e-13 conditioned to 0.0297

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
20	The Cancer Genome Atlas	Colon Adenocarcinoma	CCDC55	0.15	0.01	blup	64	0.04	1.9e-03	-6.63	7.2	6.6e-13	-0.85	0.02	0.67	TRUE
32	The Cancer Genome Atlas	Prostate Adenocarcinoma	EFCAB5	0.04	0.03	enet	10	0.02	6.0e-03	-6.26	-6.7	2.1e-11	0.85	0.04	0.92	FALSE
1	CommonMind	Brain Pre-frontal Cortex	EFCAB5	0.11	0.18	blup	392	0.17	1.7e-20	-6.37	-6.6	3.2e-11	0.91	0.11	0.89	FALSE
12	GTEx	Thyroid	ANKRD13B	0.23	0.12	lasso	6	0.18	2.3e-13	-5.17	-6.4	1.5e-10	0.67	0.92	0.08	FALSE
22	The Cancer Genome Atlas	Esophageal Carcinoma	CCDC55	0.27	0.00	blup	64	0.00	3.5e-01	-0.63	6.3	2.2e-10	-0.61	0.01	0.31	FALSE
34	The Cancer Genome Atlas	Thyroid Carcinoma	EFCAB5	0.11	0.18	enet	13	0.20	5.8e-19	-6.37	-6.3	2.3e-10	0.92	0.12	0.88	FALSE
21	The Cancer Genome Atlas	Colon Adenocarcinoma	EFCAB5	0.06	0.05	blup	79	0.03	5.7e-03	-6.37	-6.3	2.5e-10	0.92	0.03	0.94	FALSE
33	The Cancer Genome Atlas	Soft Tissue Sarcoma	EFCAB5	0.06	0.07	lasso	2	0.05	8.2e-04	-6.37	-6.3	2.6e-10	0.92	0.04	0.95	FALSE
17	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	EFCAB5	0.06	0.08	lasso	2	0.07	1.4e-06	-5.79	-6.3	2.9e-10	0.85	0.08	0.92	FALSE
3	GTEx	Brain Nucleus accumbens basal ganglia	CORO6	0.11	0.10	lasso	2	0.05	2.2e-02	-6.26	6.3	3.2e-10	-0.89	0.06	0.76	FALSE
18	The Cancer Genome Atlas	Breast Invasive Carcinoma	EFCAB5	0.02	0.04	lasso	4	0.04	1.9e-08	-6.37	-6.2	5.9e-10	0.92	0.06	0.94	FALSE
5	GTEx	Lung	SSH2	0.08	0.05	lasso	6	0.06	2.7e-05	-5.35	-6.1	8.2e-10	0.87	0.55	0.45	FALSE
19	The Cancer Genome Atlas	Breast Invasive Carcinoma	SSH2	0.01	0.01	blup	111	0.01	1.0e-03	6.63	-6.1	1.2e-09	0.95	0.10	0.87	FALSE
6	GTEx	Nerve Tibial	SSH2	0.05	0.06	lasso	10	0.06	7.8e-05	-5.82	-6.0	1.4e-09	0.94	0.14	0.86	FALSE
30	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	EFCAB5	0.04	0.04	lasso	4	0.05	5.9e-06	-5.65	-6.0	1.8e-09	0.84	0.09	0.91	FALSE
15	METSIM	Adipose	CORO6	0.02	0.02	bslmm	314	0.01	1.7e-02	-5.17	5.9	4.1e-09	-0.84	0.20	0.49	FALSE
16	METSIM	Adipose	SSH2	0.03	0.03	blup	422	0.02	1.5e-04	6.75	-5.9	4.2e-09	0.90	0.16	0.84	FALSE
27	The Cancer Genome Atlas	Brain Lower Grade Glioma	EFCAB5	0.07	0.09	enet	16	0.08	4.0e-09	-6.18	-5.8	8.9e-09	0.88	0.05	0.95	FALSE
35	The Cancer Genome Atlas	Thyroid Carcinoma	GIT1	0.06	0.05	blup	47	0.05	5.2e-06	4.86	-5.7	9.2e-09	0.70	0.04	0.96	FALSE
25	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SSH2	0.03	0.02	blup	112	0.03	2.4e-04	-5.59	-5.7	9.8e-09	0.92	0.29	0.67	FALSE
28	The Cancer Genome Atlas	Lung Adenocarcinoma	EFCAB5	0.06	0.09	lasso	1	0.09	2.9e-10	-5.72	-5.7	1.0e-08	0.92	0.52	0.48	FALSE
4	GTEx	Esophagus Muscularis	SSH2	0.04	0.01	enet	10	0.00	3.3e-01	-5.72	-5.6	1.9e-08	0.83	0.32	0.43	FALSE
23	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	EFCAB5	0.10	0.05	enet	24	0.04	2.0e-05	-6.37	-5.5	3.1e-08	0.69	0.01	0.98	FALSE
31	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	EFCAB5	0.08	0.01	blup	79	0.03	1.7e-02	-5.73	-5.5	3.1e-08	0.89	0.04	0.60	FALSE
24	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	EFCAB5	0.09	0.12	lasso	5	0.12	3.1e-13	-5.42	-5.5	4.6e-08	0.86	0.37	0.63	FALSE
13	METSIM	Adipose	ANKRD13B	0.04	0.03	lasso	3	0.05	1.4e-07	-5.66	5.5	4.9e-08	-0.81	0.11	0.89	FALSE
7	GTEx	Skin Sun Exposed Lower leg	ANKRD13B	0.08	0.04	lasso	5	0.06	1.4e-05	6.54	5.4	5.7e-08	-0.71	0.09	0.88	FALSE
10	GTEx	Thyroid	SSH2	0.12	0.17	enet	10	0.18	2.0e-13	4.70	-5.4	7.0e-08	0.77	0.99	0.01	FALSE
2	GTEx	Artery Tibial	BLMH	0.12	0.04	enet	16	0.08	6.7e-07	3.30	-5.4	8.2e-08	0.78	0.35	0.65	FALSE
9	GTEx	Thyroid	GIT1	0.06	0.08	lasso	5	0.09	3.7e-07	4.86	-5.3	9.8e-08	0.80	0.53	0.47	FALSE
8	GTEx	Skin Sun Exposed Lower leg	RP11-68I3.4	0.03	0.00	lasso	3	0.00	4.5e-01	4.85	-5.3	1.3e-07	0.69	0.08	0.12	FALSE
11	GTEx	Thyroid	CORO6	0.23	0.36	lasso	5	0.37	1.2e-29	4.70	-5.2	1.6e-07	0.75	1.00	0.00	FALSE
26	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	EFCAB5	0.05	0.02	enet	22	0.02	1.7e-02	-6.23	-5.2	1.6e-07	0.82	0.04	0.72	FALSE
14	METSIM	Adipose	BLMH	0.03	0.03	blup	304	0.03	6.0e-05	2.53	-5.2	1.8e-07	0.78	0.71	0.20	FALSE
29	The Cancer Genome Atlas	Lung Adenocarcinoma	SSH2	0.06	0.03	blup	112	0.05	2.5e-06	4.70	-5.2	2.5e-07	0.89	0.10	0.90	FALSE