[Hub]/) : Traits : Leg predicted mass (right) :

chr14:34,480,400-36,571,554

Best TWAS P=2.21e-10 · Best GWAS P=4.77e-11 conditioned to 9.19e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PPP2R3C 0.21 0.12 lasso 10 0.14 2.6e-11 -6.2 5.8 7.0e-09 0.15 0.05 0.95 FALSE
2 GTEx Cells Transformed fibroblasts PPP2R3C 0.31 0.10 lasso 10 0.18 4.0e-13 -6.2 6.1 1.1e-09 0.26 0.04 0.96 FALSE
3 GTEx Cells Transformed fibroblasts CFL2 0.14 0.08 enet 39 0.11 9.9e-09 -2.5 -6.3 2.2e-10 -0.06 0.59 0.04 TRUE
4 GTEx Thyroid FAM177A1 0.13 0.04 enet 18 0.07 5.5e-06 -4.7 5.2 2.3e-07 0.19 0.63 0.36 FALSE
5 NTR Blood KIAA0391 0.05 0.05 lasso 10 0.05 2.4e-15 -6.2 -5.2 2.2e-07 -0.14 0.03 0.97 FALSE
6 NTR Blood NFKBIA 0.26 0.09 lasso 10 0.12 3.4e-36 -4.1 -6.1 1.1e-09 -0.50 1.00 0.00 FALSE
7 YFS Blood KIAA0391 0.29 0.36 lasso 7 0.38 5.8e-132 -6.2 -6.1 1.2e-09 -0.18 0.03 0.97 FALSE
8 YFS Blood NFKBIA 0.24 0.11 enet 33 0.17 3.5e-53 -4.0 -6.3 3.8e-10 -0.43 1.00 0.00 TRUE
9 The Cancer Genome Atlas Brain Lower Grade Glioma PPP2R3C 0.08 0.04 blup 51 0.07 7.8e-09 -4.9 6.3 2.3e-10 0.27 0.01 0.99 FALSE
10 The Cancer Genome Atlas Thyroid Carcinoma KIAA0391 0.12 0.11 enet 14 0.14 2.0e-13 -4.1 5.1 3.1e-07 -0.03 0.74 0.26 FALSE