[Hub]/) : Traits : Leg fat percentage (left) :

chr20:31,981,432-34,737,037

Best TWAS P=1.62e-10 · Best GWAS P=3.75e-10 conditioned to 0.00371

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PROCR 0.05 0.04 lasso 6 0.03 8.0e-05 -5.4 5.8 8.4e-09 -0.41 0.22 0.72 FALSE
2 CommonMind Brain Pre-frontal Cortex UQCC 0.07 0.04 lasso 2 0.05 1.4e-06 -5.6 5.3 1.1e-07 -0.23 0.02 0.98 FALSE
3 GTEx Adipose Subcutaneous UQCC1 0.09 0.12 lasso 2 0.11 4.5e-09 -6.0 5.9 3.1e-09 -0.18 0.02 0.98 FALSE
4 GTEx Adipose Visceral Omentum UQCC1 0.15 0.08 lasso 7 0.07 1.6e-04 -6.0 5.5 3.1e-08 -0.07 0.03 0.96 FALSE
5 GTEx Adrenal Gland MMP24-AS1 0.18 0.04 enet 10 0.13 2.2e-05 -4.7 5.4 5.9e-08 -0.10 0.15 0.45 FALSE
6 GTEx Breast Mammary Tissue MMP24-AS1 0.15 0.06 enet 10 0.08 7.1e-05 -3.9 5.7 1.1e-08 -0.40 0.18 0.46 FALSE
7 GTEx Breast Mammary Tissue (Male) UQCC1 0.06 0.04 lasso 1 0.02 1.4e-01 -6.2 6.2 5.0e-10 -0.18 0.03 0.29 FALSE
8 GTEx Cells EBV-transformed lymphocytes PROCR 0.19 0.05 enet 25 0.09 7.3e-04 -5.5 -5.3 9.8e-08 0.38 0.06 0.46 FALSE
9 GTEx Cells Transformed fibroblasts PROCR 0.14 0.13 lasso 2 0.11 1.9e-08 -5.2 5.2 2.1e-07 -0.45 0.64 0.36 FALSE
10 GTEx Cells Transformed fibroblasts UQCC1 0.23 0.24 lasso 8 0.25 9.4e-19 -6.0 5.7 1.1e-08 -0.14 0.02 0.98 FALSE
11 GTEx Cells Transformed fibroblasts MMP24 0.11 0.03 enet 11 0.04 8.5e-04 -3.9 5.4 5.3e-08 -0.38 0.37 0.54 FALSE
12 GTEx Esophagus Mucosa UQCC1 0.13 0.10 enet 10 0.07 1.1e-05 -6.2 6.4 1.6e-10 -0.28 0.02 0.98 TRUE
13 GTEx Lung UQCC1 0.13 0.08 lasso 5 0.06 1.0e-05 -6.0 6.0 2.2e-09 -0.19 0.02 0.98 FALSE
14 GTEx Lung EIF6 0.20 0.10 lasso 6 0.09 3.4e-07 -5.9 -5.9 3.9e-09 0.49 0.06 0.94 FALSE
15 GTEx Lung RP4-614O4.11 0.18 0.04 lasso 6 0.07 8.8e-06 -5.9 -5.6 2.5e-08 0.53 0.10 0.87 FALSE
16 GTEx Muscle Skeletal MMP24-AS1 0.27 0.06 lasso 3 0.04 1.3e-04 -4.0 5.3 1.3e-07 -0.35 0.34 0.44 FALSE
17 GTEx Nerve Tibial UQCC1 0.07 0.04 enet 6 0.03 2.7e-03 -6.0 5.6 2.6e-08 -0.11 0.03 0.96 FALSE
18 GTEx Skin Not Sun Exposed Suprapubic MMP24 0.30 0.07 lasso 7 0.10 5.6e-06 -5.9 6.0 2.7e-09 -0.44 0.12 0.84 FALSE
19 GTEx Skin Not Sun Exposed Suprapubic MMP24-AS1 0.13 0.04 lasso 6 0.04 3.3e-03 -5.9 6.0 2.0e-09 -0.46 0.07 0.45 FALSE
20 GTEx Skin Not Sun Exposed Suprapubic RP4-614O4.11 0.26 0.04 lasso 8 0.03 6.9e-03 -4.1 -5.1 2.9e-07 0.33 0.66 0.20 FALSE
21 GTEx Skin Sun Exposed Lower leg UQCC1 0.19 0.13 enet 16 0.10 8.1e-09 -6.0 5.3 1.4e-07 -0.28 0.02 0.98 FALSE
22 GTEx Skin Sun Exposed Lower leg MMP24 0.42 0.14 lasso 8 0.14 2.5e-11 -5.9 6.2 7.6e-10 -0.43 0.05 0.95 FALSE
23 GTEx Skin Sun Exposed Lower leg MMP24-AS1 0.61 0.13 lasso 17 0.12 4.8e-10 -5.9 5.7 1.3e-08 -0.41 0.05 0.95 FALSE
24 GTEx Small Intestine Terminal Ileum MAP1LC3A 0.45 0.01 lasso 9 0.05 3.3e-02 -5.7 -5.5 3.4e-08 0.75 0.04 0.73 FALSE
25 GTEx Stomach UQCC1 0.09 0.14 lasso 2 0.15 1.9e-07 -6.0 6.2 6.7e-10 -0.29 0.02 0.97 FALSE
26 GTEx Whole Blood MMP24-AS1 0.21 0.07 lasso 5 0.09 1.5e-08 -4.0 5.1 3.1e-07 -0.33 0.65 0.34 FALSE
27 METSIM Adipose UQCC1 0.09 0.04 enet 18 0.05 1.5e-07 -6.0 6.1 8.9e-10 -0.21 0.02 0.98 FALSE
28 NTR Blood EIF6 0.07 0.05 lasso 3 0.05 4.1e-16 -5.9 -6.0 1.8e-09 0.50 0.05 0.95 FALSE
29 NTR Blood UQCC 0.01 0.01 enet 6 0.00 1.6e-02 -6.0 5.9 2.8e-09 -0.18 0.02 0.95 FALSE
30 ROSMAP Brain Pre-frontal Cortex TRPC4AP 0.05 0.03 lasso 4 0.03 8.7e-05 -5.5 5.6 2.3e-08 -0.46 0.36 0.46 FALSE
31 ROSMAP Brain Pre-frontal Cortex UQCC1 0.05 0.05 lasso 5 0.06 1.7e-08 -6.2 6.2 5.1e-10 -0.25 0.02 0.98 FALSE
32 ROSMAP Brain Pre-frontal Cortex GDF5 0.10 0.13 lasso 2 0.12 2.9e-15 -6.0 -6.0 1.8e-09 0.19 0.02 0.98 FALSE
33 YFS Blood EIF2S2 0.07 0.07 enet 25 0.06 4.3e-20 -5.0 5.6 1.9e-08 -0.33 0.50 0.50 TRUE
34 YFS Blood EIF6 0.02 0.00 blup 341 0.01 4.1e-05 -2.5 -5.3 9.6e-08 0.46 0.83 0.08 FALSE
35 YFS Blood UQCC 0.21 0.19 lasso 26 0.20 6.4e-64 -6.0 6.0 2.5e-09 -0.27 0.02 0.98 FALSE
36 The Cancer Genome Atlas Bladder Urothelial Carcinoma MMP24 0.10 0.03 enet 14 0.05 5.1e-05 -3.9 5.7 1.1e-08 -0.39 0.11 0.70 FALSE
37 The Cancer Genome Atlas Bladder Urothelial Carcinoma UQCC 0.03 0.04 blup 67 0.03 2.6e-03 -6.0 6.3 3.4e-10 -0.24 0.02 0.90 FALSE
38 The Cancer Genome Atlas Breast Invasive Carcinoma UQCC 0.08 0.11 blup 67 0.12 1.1e-22 -6.2 5.3 1.1e-07 -0.09 0.02 0.98 FALSE
39 The Cancer Genome Atlas Colon Adenocarcinoma PROCR 0.09 0.07 lasso 2 0.06 2.0e-04 -5.5 5.5 3.2e-08 -0.48 0.01 0.97 FALSE
40 The Cancer Genome Atlas Glioblastoma Multiforme UQCC 0.15 0.02 blup 67 0.04 2.0e-02 -3.2 6.0 2.5e-09 -0.40 0.02 0.51 FALSE
41 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma EIF6 0.03 0.03 enet 11 0.03 2.4e-04 -4.1 -5.2 2.0e-07 0.35 0.06 0.17 FALSE
42 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma UQCC 0.05 0.06 blup 66 0.06 3.6e-07 -4.8 5.7 1.4e-08 -0.10 0.02 0.98 FALSE
43 The Cancer Genome Atlas Brain Lower Grade Glioma GDF5 0.09 0.11 blup 76 0.12 1.0e-13 -6.0 -6.4 2.1e-10 0.37 0.02 0.98 FALSE
44 The Cancer Genome Atlas Brain Lower Grade Glioma PROCR 0.10 0.11 lasso 4 0.12 5.5e-13 -5.6 5.3 9.1e-08 -0.48 0.00 1.00 FALSE
45 The Cancer Genome Atlas Brain Lower Grade Glioma UQCC 0.04 0.06 lasso 6 0.05 2.3e-06 -6.0 6.0 1.8e-09 -0.19 0.02 0.98 FALSE
46 The Cancer Genome Atlas Lung Adenocarcinoma UQCC 0.10 0.07 enet 10 0.07 1.5e-08 -6.2 5.9 2.7e-09 -0.15 0.01 0.99 FALSE
47 The Cancer Genome Atlas Lung Squamous Cell Carcinoma UQCC 0.07 0.08 blup 67 0.07 1.1e-08 -6.0 6.1 8.4e-10 -0.26 0.02 0.98 FALSE
48 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma GDF5 0.05 0.02 blup 76 0.04 1.4e-03 -6.0 -6.0 1.5e-09 0.25 0.02 0.95 FALSE
49 The Cancer Genome Atlas Pancreatic Adenocarcinoma EIF6 0.31 0.11 lasso 6 0.08 2.8e-04 -5.9 -6.0 1.5e-09 0.45 0.01 0.87 FALSE
50 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma UQCC 0.22 0.21 lasso 7 0.18 1.9e-07 -6.0 5.3 1.4e-07 -0.12 0.02 0.98 FALSE
51 The Cancer Genome Atlas Prostate Adenocarcinoma GDF5 0.05 0.05 lasso 5 0.04 7.2e-05 -6.2 -6.0 1.6e-09 0.16 0.01 0.98 FALSE
52 The Cancer Genome Atlas Prostate Adenocarcinoma MMP24 0.19 0.21 enet 7 0.24 1.6e-24 -3.9 5.4 7.6e-08 -0.36 0.97 0.03 FALSE
53 The Cancer Genome Atlas Prostate Adenocarcinoma PROCR 0.04 0.05 lasso 4 0.03 3.6e-04 -5.2 5.3 1.4e-07 -0.45 0.01 0.96 FALSE
54 The Cancer Genome Atlas Prostate Adenocarcinoma UQCC 0.07 0.10 lasso 8 0.11 1.3e-11 -6.0 6.0 2.4e-09 -0.19 0.02 0.98 FALSE
55 The Cancer Genome Atlas Soft Tissue Sarcoma UQCC 0.07 0.06 blup 66 0.07 5.2e-05 -6.0 6.2 6.0e-10 -0.18 0.02 0.98 FALSE
56 The Cancer Genome Atlas Stomach Adenocarcinoma PROCR 0.10 0.06 lasso 3 0.06 2.8e-05 -5.5 5.5 4.7e-08 -0.47 0.00 0.99 FALSE
57 The Cancer Genome Atlas Stomach Adenocarcinoma UQCC 0.07 0.06 lasso 10 0.06 2.8e-05 -5.6 5.7 1.1e-08 -0.19 0.02 0.98 FALSE
58 The Cancer Genome Atlas Thyroid Carcinoma GDF5 0.02 0.00 blup 76 0.00 1.9e-01 -6.2 -5.7 1.4e-08 0.18 0.02 0.90 FALSE
59 The Cancer Genome Atlas Thyroid Carcinoma PROCR 0.09 0.06 blup 45 0.08 3.0e-08 -5.5 5.3 1.2e-07 -0.47 0.01 0.99 FALSE
60 The Cancer Genome Atlas Thyroid Carcinoma UQCC 0.15 0.21 blup 67 0.22 1.2e-20 -6.2 5.6 1.7e-08 -0.15 0.01 0.99 FALSE