[Hub]/) : Traits : Leg predicted mass (left) : ← →

chr4:305,291-2,437,290

Best TWAS P=7.31e-12 · Best GWAS P=4.94e-13 conditioned to 0.00018

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	CRIPAK	0.31	0.15	enet	34	0.26	1.2e-31	-3.21	-5.4	6.8e-08	0.04	1.00	0.00	FALSE
2	GTEx	Brain Cortex	TACC3	0.26	0.13	lasso	4	0.17	1.7e-05	-5.23	5.1	2.8e-07	0.52	0.26	0.26	FALSE
3	GTEx	Brain Cortex	CRIPAK	0.34	0.10	lasso	6	0.18	9.5e-06	-4.14	-5.8	7.1e-09	0.03	0.19	0.10	FALSE
4	GTEx	Brain Hippocampus	CRIPAK	0.48	0.22	lasso	4	0.23	4.0e-06	-3.57	-6.0	2.5e-09	0.00	0.18	0.14	FALSE
5	GTEx	Brain Putamen basal ganglia	CRIPAK	0.30	0.00	enet	25	0.10	1.9e-03	-3.10	-5.2	2.6e-07	0.11	0.06	0.10	FALSE
6	GTEx	Breast Mammary Tissue (Female)	CRIPAK	0.32	0.17	enet	29	0.26	2.7e-08	-3.14	-5.7	1.2e-08	0.01	0.53	0.03	FALSE
7	GTEx	Colon Transverse	TMEM129	0.23	0.05	lasso	4	0.03	1.8e-02	-5.23	5.9	4.2e-09	0.51	0.09	0.09	FALSE
8	GTEx	Lung	CRIPAK	0.61	0.22	enet	46	0.41	1.1e-33	-4.14	-6.3	2.5e-10	0.02	1.00	0.00	FALSE
9	GTEx	Muscle Skeletal	FGFRL1	0.14	0.08	lasso	4	0.06	3.7e-06	-6.66	6.0	1.4e-09	0.01	0.00	1.00	TRUE
10	GTEx	Muscle Skeletal	CRIPAK	0.25	0.11	enet	32	0.18	7.6e-18	-4.14	-5.3	9.2e-08	0.03	1.00	0.00	FALSE
11	GTEx	Nerve Tibial	CRIPAK	0.50	0.11	enet	76	0.38	1.1e-28	-3.57	-6.2	6.3e-10	-0.08	1.00	0.00	FALSE
12	GTEx	Ovary	CRIPAK	0.43	0.27	enet	19	0.32	9.0e-09	-4.14	-5.4	7.1e-08	0.03	0.46	0.06	FALSE
13	GTEx	Pancreas	CRIPAK	0.34	0.13	lasso	6	0.27	1.0e-11	-3.57	-5.1	2.7e-07	0.01	0.84	0.01	FALSE
14	GTEx	Thyroid	AC016773.1	0.11	0.07	enet	7	0.06	3.9e-05	-5.37	5.2	2.2e-07	0.52	0.67	0.04	FALSE
15	GTEx	Whole Blood	CRIPAK	0.38	0.17	lasso	9	0.28	3.4e-26	-3.57	-5.3	1.0e-07	0.02	1.00	0.00	FALSE
16	METSIM	Adipose	CRIPAK	0.28	0.16	bslmm	335	0.25	2.7e-37	-3.30	-6.3	3.0e-10	-0.01	1.00	0.00	FALSE
17	METSIM	Adipose	UVSSA	0.26	0.04	bslmm	366	0.12	9.0e-18	0.87	-5.5	3.2e-08	0.02	0.98	0.02	FALSE
18	NTR	Blood	CRIPAK	0.13	0.09	enet	31	0.15	1.5e-46	-3.02	-6.8	7.3e-12	0.00	1.00	0.00	TRUE
19	NTR	Blood	KIAA1530	0.19	0.04	blup	345	0.10	9.1e-32	-3.60	-6.4	1.7e-10	0.08	1.00	0.00	FALSE
20	NTR	Blood	SLBP	0.04	0.02	lasso	5	0.02	2.8e-08	-5.37	6.2	7.5e-10	0.82	0.03	0.97	TRUE
21	NTR	Blood	TACC3	0.05	0.03	lasso	9	0.04	2.7e-13	-5.17	6.1	9.5e-10	0.71	0.50	0.50	FALSE
22	ROSMAP	Brain Pre-frontal Cortex	AC016773.1	0.12	0.06	lasso	3	0.10	3.0e-12	-5.37	5.2	2.1e-07	0.52	1.00	0.00	FALSE
23	YFS	Blood	CRIPAK	0.35	0.27	bslmm	301	0.33	6.0e-112	-3.57	-5.5	3.4e-08	-0.03	1.00	0.00	FALSE
24	YFS	Blood	SLBP	0.10	0.12	lasso	3	0.12	1.2e-35	-5.17	5.1	2.8e-07	0.60	1.00	0.00	FALSE
25	The Cancer Genome Atlas	Breast Invasive Carcinoma	CRIPAK	0.22	0.11	blup	28	0.14	5.6e-28	-3.57	-5.6	2.4e-08	0.01	0.00	0.40	FALSE
26	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CRIPAK	0.28	0.16	blup	28	0.19	3.2e-21	-3.57	-5.2	2.1e-07	0.03	0.00	0.40	FALSE
27	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	TACC3	0.09	0.08	enet	7	0.11	2.7e-05	-5.17	5.2	2.3e-07	0.52	0.13	0.21	FALSE
28	The Cancer Genome Atlas	Thyroid Carcinoma	CRIPAK	0.38	0.22	enet	12	0.25	5.4e-24	-3.57	-5.2	2.0e-07	0.01	0.00	0.40	FALSE