[Hub]/) : Traits : Arm fat-free mass (right) : ← →

chr8:8,165,004-12,973,575

Best TWAS P=3.73e-10 · Best GWAS P=2e-10 conditioned to 0.124

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
46	GTEx	Vagina	AF131215.9	0.21	0.11	lasso	9	0.08	6.3e-03	6.3	6.3	3.7e-10	-0.92	0.03	0.94	TRUE
24	GTEx	Esophagus Muscularis	AF131215.9	0.14	0.17	enet	16	0.17	1.6e-10	-5.8	6.2	5.4e-10	-0.86	0.12	0.88	FALSE
33	GTEx	Pancreas	AF131215.9	0.25	0.24	enet	14	0.22	1.0e-09	5.7	6.2	6.3e-10	-0.90	0.07	0.93	FALSE
27	GTEx	Heart Left Ventricle	AF131215.9	0.07	0.10	enet	8	0.10	9.4e-06	-5.7	6.1	1.0e-09	-0.87	0.10	0.89	FALSE
39	GTEx	Skin Sun Exposed Lower leg	AF131215.9	0.19	0.17	enet	29	0.21	3.9e-17	-5.7	6.0	1.5e-09	-0.86	0.15	0.85	FALSE
32	GTEx	Pancreas	AF131215.2	0.16	0.16	enet	17	0.15	9.1e-07	-5.8	6.0	1.9e-09	-0.88	0.12	0.88	FALSE
43	GTEx	Thyroid	AF131215.2	0.11	0.15	enet	17	0.18	1.2e-13	-5.1	6.0	2.0e-09	-0.87	0.28	0.72	FALSE
51	ROSMAP	Brain Pre-frontal Cortex	AF131215.3	0.08	0.10	lasso	7	0.12	8.3e-16	5.7	6.0	2.0e-09	-0.86	0.04	0.96	FALSE
7	GTEx	Adrenal Gland	AF131215.2	0.20	0.16	enet	12	0.13	2.2e-05	5.8	6.0	2.4e-09	-0.90	0.02	0.98	FALSE
28	GTEx	Lung	AF131215.2	0.12	0.08	lasso	5	0.08	1.0e-06	-5.7	6.0	2.5e-09	-0.86	0.13	0.87	FALSE
11	GTEx	Artery Aorta	AF131215.9	0.13	0.05	lasso	6	0.07	1.3e-04	5.7	5.9	2.9e-09	-0.88	0.09	0.91	FALSE
22	GTEx	Esophagus Mucosa	AF131215.9	0.18	0.16	lasso	14	0.19	1.6e-12	5.3	5.9	3.4e-09	-0.89	0.07	0.93	FALSE
8	GTEx	Adrenal Gland	AF131215.9	0.18	0.16	lasso	10	0.18	3.5e-07	5.8	5.9	3.5e-09	-0.87	0.04	0.96	FALSE
6	GTEx	Adipose Visceral Omentum	AF131215.9	0.18	0.16	lasso	7	0.16	2.0e-08	5.7	5.9	3.8e-09	-0.87	0.06	0.94	FALSE
49	ROSMAP	Brain Pre-frontal Cortex	XKR6	0.11	0.10	enet	23	0.13	1.2e-16	-4.7	5.9	3.8e-09	-0.81	0.29	0.71	FALSE
10	GTEx	Artery Aorta	AF131215.2	0.09	0.09	lasso	7	0.08	2.0e-05	-5.3	5.9	4.1e-09	-0.86	0.10	0.90	FALSE
30	GTEx	Nerve Tibial	AF131215.2	0.19	0.18	lasso	12	0.23	3.5e-16	-5.1	5.9	4.8e-09	-0.89	0.24	0.76	FALSE
52	ROSMAP	Brain Pre-frontal Cortex	AF131215.2	0.49	0.57	lasso	7	0.57	9.0e-89	-5.7	5.8	5.0e-09	-0.87	0.11	0.89	FALSE
16	GTEx	Cells EBV-transformed lymphocytes	AF131215.9	0.20	0.15	enet	19	0.13	5.6e-05	-5.7	5.8	5.2e-09	-0.79	0.15	0.80	FALSE
29	GTEx	Lung	AF131215.9	0.15	0.18	lasso	4	0.15	1.5e-11	-5.7	5.8	5.7e-09	-0.86	0.12	0.88	FALSE
12	GTEx	Brain Cerebellar Hemisphere	AF131215.2	0.15	0.17	lasso	3	0.09	3.0e-03	-5.7	5.8	7.7e-09	-0.86	0.06	0.80	FALSE
26	GTEx	Heart Left Ventricle	AF131215.2	0.05	0.01	enet	11	0.01	1.5e-01	5.7	5.8	7.9e-09	-0.86	0.08	0.83	FALSE
36	GTEx	Skin Not Sun Exposed Suprapubic	AF131215.9	0.17	0.14	lasso	8	0.19	9.4e-11	-5.7	5.8	7.9e-09	-0.86	0.10	0.90	FALSE
45	GTEx	Uterus	AF131215.2	0.17	0.07	enet	13	0.09	7.1e-03	5.8	5.8	7.9e-09	-0.87	0.05	0.83	FALSE
5	GTEx	Adipose Visceral Omentum	AF131215.2	0.12	0.08	lasso	6	0.06	4.6e-04	5.7	5.8	8.8e-09	-0.86	0.15	0.83	FALSE
50	ROSMAP	Brain Pre-frontal Cortex	FAM66A	0.23	0.26	enet	29	0.30	4.7e-39	5.4	5.7	9.4e-09	-0.60	0.00	1.00	FALSE
42	GTEx	Testis	AF131215.2	0.28	0.18	enet	41	0.17	8.0e-08	-5.1	5.7	1.0e-08	-0.65	0.74	0.26	FALSE
31	GTEx	Nerve Tibial	AF131215.9	0.17	0.17	lasso	4	0.18	5.0e-13	-5.7	5.7	1.4e-08	-0.86	0.14	0.86	FALSE
17	GTEx	Cells Transformed fibroblasts	ERI1	0.34	0.35	lasso	7	0.35	1.9e-27	5.5	-5.7	1.5e-08	0.59	0.00	1.00	FALSE
37	GTEx	Skin Sun Exposed Lower leg	AF131215.2	0.14	0.11	lasso	9	0.16	4.3e-13	-5.1	5.7	1.5e-08	-0.85	0.47	0.53	FALSE
15	GTEx	Cells EBV-transformed lymphocytes	AF131215.2	0.20	0.10	enet	14	0.11	1.5e-04	-5.7	5.6	1.6e-08	-0.85	0.13	0.84	FALSE
18	GTEx	Colon Sigmoid	AF131215.9	0.11	0.17	enet	5	0.09	4.9e-04	-5.8	5.6	1.8e-08	-0.87	0.09	0.80	FALSE
44	GTEx	Thyroid	AF131215.9	0.11	0.08	enet	16	0.17	4.7e-13	-5.8	5.6	1.9e-08	-0.86	0.14	0.86	FALSE
54	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	ERI1	0.05	0.01	blup	72	0.01	5.0e-02	5.5	-5.6	2.0e-08	0.50	0.01	0.80	FALSE
3	GTEx	Adipose Subcutaneous	AF131215.2	0.24	0.15	lasso	7	0.14	3.5e-11	-5.3	5.6	2.3e-08	-0.82	0.40	0.60	FALSE
1	CommonMind	Brain Pre-frontal Cortex	FAM86B1	0.02	0.02	lasso	3	0.01	1.3e-02	4.6	5.6	2.7e-08	-0.63	0.01	0.96	FALSE
4	GTEx	Adipose Subcutaneous	AF131215.9	0.20	0.12	enet	60	0.17	1.1e-13	-5.3	5.6	2.7e-08	-0.67	0.16	0.84	FALSE
20	GTEx	Colon Transverse	AF131215.9	0.12	0.14	enet	18	0.12	4.0e-06	-5.7	5.5	2.9e-08	-0.88	0.09	0.90	FALSE
2	CommonMind	Brain Pre-frontal Cortex	FAM90A25P	0.11	0.08	lasso	3	0.08	1.4e-09	5.2	5.5	3.6e-08	-0.58	0.00	1.00	FALSE
35	GTEx	Skin Not Sun Exposed Suprapubic	AF131215.2	0.16	0.11	enet	21	0.20	3.9e-11	-5.1	5.5	4.1e-08	-0.87	0.09	0.91	FALSE
34	GTEx	Prostate	AF131215.2	0.18	0.02	lasso	6	0.02	9.6e-02	3.5	5.5	4.5e-08	-0.74	0.08	0.51	FALSE
55	The Cancer Genome Atlas	Breast Invasive Carcinoma	TDH	0.03	0.04	lasso	4	0.03	1.2e-07	-5.6	-5.5	4.9e-08	0.55	0.00	1.00	FALSE
23	GTEx	Esophagus Muscularis	FAM85A	0.10	0.01	enet	20	0.04	2.7e-03	-4.1	5.4	7.8e-08	-0.53	0.06	0.85	FALSE
21	GTEx	Esophagus Mucosa	AF131215.2	0.15	0.14	enet	15	0.18	4.3e-12	-5.1	5.4	8.8e-08	-0.84	0.58	0.42	FALSE
56	The Cancer Genome Atlas	Testicular Germ Cell Tumors	ZNF705D	0.23	0.20	lasso	3	0.24	4.7e-09	5.4	-5.3	1.1e-07	0.55	0.00	1.00	FALSE
40	GTEx	Spleen	AF131215.2	0.16	0.08	enet	14	0.06	1.1e-02	-5.7	5.3	1.2e-07	-0.88	0.04	0.90	FALSE
38	GTEx	Skin Sun Exposed Lower leg	FAM85A	0.09	0.04	enet	28	0.04	1.4e-04	-4.1	5.2	1.5e-07	-0.45	0.08	0.82	FALSE
53	ROSMAP	Brain Pre-frontal Cortex	FAM85A	0.11	0.07	enet	23	0.11	4.3e-14	5.4	5.2	1.5e-07	-0.60	0.00	0.99	FALSE
13	GTEx	Breast Mammary Tissue	AF131215.2	0.16	0.15	lasso	6	0.12	1.1e-06	-5.3	5.2	1.6e-07	-0.80	0.42	0.55	FALSE
25	GTEx	Heart Atrial Appendage	AF131215.2	0.39	0.13	enet	26	0.21	6.6e-10	-5.1	5.2	1.6e-07	-0.75	0.64	0.36	FALSE
48	ROSMAP	Brain Pre-frontal Cortex	FAM167A	0.12	0.03	bslmm	620	0.08	1.3e-10	2.2	-5.2	1.6e-07	0.66	0.46	0.54	FALSE
41	GTEx	Spleen	AF131215.9	0.34	0.23	enet	16	0.15	1.2e-04	6.2	5.2	1.9e-07	-0.88	0.02	0.98	FALSE
14	GTEx	Breast Mammary Tissue	AF131215.9	0.10	0.10	lasso	8	0.12	8.7e-07	-4.3	5.2	2.2e-07	-0.79	0.28	0.72	FALSE
19	GTEx	Colon Transverse	AF131215.2	0.15	0.09	enet	32	0.07	3.1e-04	5.7	5.2	2.5e-07	-0.78	0.11	0.86	FALSE
47	NTR	Blood	MSRA	0.02	0.01	blup	833	0.01	2.3e-05	3.9	-5.2	2.5e-07	0.61	0.25	0.73	FALSE
9	GTEx	Artery Aorta	ERI1	0.11	0.08	lasso	5	0.10	5.1e-06	5.5	-5.1	3.0e-07	0.60	0.00	0.99	FALSE