[Hub]/) : Traits : Arm fat-free mass (right) :

chr17:45,228,469-47,688,526

Best TWAS P=2.16e-13 · Best GWAS P=2.07e-09 conditioned to 9.94e-07

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex TTLL6 0.23 0.12 bslmm 418 0.15 1.7e-17 1.1 -6.1 1.1e-09 -0.09 0.52 0.48 FALSE
2 GTEx Brain Cerebellum CALCOCO2 0.25 0.08 enet 11 0.11 4.3e-04 -4.6 -5.3 1.3e-07 0.21 0.03 0.88 FALSE
3 GTEx Brain Nucleus accumbens basal ganglia CDK5RAP3 0.21 0.04 lasso 4 0.02 7.2e-02 5.6 -5.2 2.5e-07 0.06 0.03 0.75 FALSE
4 GTEx Brain Nucleus accumbens basal ganglia RP11-6N17.9 0.47 0.05 lasso 17 0.11 8.3e-04 4.9 -5.5 3.7e-08 -0.07 0.04 0.76 TRUE
5 GTEx Cells EBV-transformed lymphocytes HOXB3 0.28 0.00 lasso 7 0.00 5.0e-01 -4.2 -6.2 7.8e-10 0.17 0.04 0.17 FALSE
6 GTEx Liver SCRN2 0.32 0.05 enet 14 0.11 5.5e-04 -4.9 5.8 5.0e-09 -0.29 0.09 0.60 TRUE
7 GTEx Stomach RP11-6N17.9 0.13 0.02 lasso 6 0.04 8.0e-03 4.6 -5.1 2.7e-07 0.15 0.06 0.83 FALSE
8 GTEx Testis RP11-6N17.4 0.14 0.02 lasso 10 0.02 4.8e-02 5.5 5.2 1.5e-07 -0.06 0.04 0.92 FALSE
9 YFS Blood UBE2Z 0.06 0.03 enet 19 0.06 1.5e-18 2.5 6.3 3.4e-10 -0.06 0.32 0.68 FALSE
10 The Cancer Genome Atlas Lung Adenocarcinoma ATP5G1 0.04 0.01 enet 6 0.03 5.4e-05 4.9 6.4 1.3e-10 -0.17 0.04 0.84 FALSE
11 The Cancer Genome Atlas Lung Adenocarcinoma CALCOCO2 0.04 0.03 blup 50 0.02 1.6e-03 -4.2 7.3 2.2e-13 -0.04 0.02 0.21 TRUE
12 The Cancer Genome Atlas Prostate Adenocarcinoma CALCOCO2 0.08 0.03 blup 50 0.07 1.4e-07 -4.2 6.8 1.5e-11 -0.19 0.03 0.97 FALSE
13 The Cancer Genome Atlas Prostate Adenocarcinoma CBX1 0.03 0.04 lasso 4 0.04 3.7e-05 5.5 -5.5 2.9e-08 0.05 0.02 0.96 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma MRPL10 0.07 0.00 blup 59 0.02 8.7e-03 -4.9 -5.4 5.5e-08 0.27 0.00 0.56 FALSE