[Hub]/) : Traits : Arm fat percentage (left) :

chr15:51,040,798-53,052,565

Best TWAS P=8.78e-09 · Best GWAS P=5.38e-09 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells EBV-transformed lymphocytes DMXL2 0.17 0.13 lasso 3 0.06 4.2e-03 5.4 5.3 1.5e-07 -0.45 0.22 0.57 FALSE
2 GTEx Cells Transformed fibroblasts DMXL2 0.06 0.06 lasso 3 0.05 5.9e-05 5.3 -5.3 1.3e-07 0.28 0.32 0.60 TRUE
3 GTEx Cells Transformed fibroblasts TMOD2 0.09 0.10 enet 8 0.10 3.0e-08 -5.6 -5.7 1.3e-08 0.99 0.04 0.96 FALSE
4 GTEx Muscle Skeletal LYSMD2 0.23 0.23 lasso 4 0.21 1.6e-20 -5.7 5.7 1.1e-08 -0.97 0.04 0.96 FALSE
5 GTEx Skin Not Sun Exposed Suprapubic TMOD3 0.05 0.07 enet 13 0.07 6.4e-05 -5.8 5.4 7.9e-08 -0.98 0.05 0.94 FALSE
6 GTEx Skin Sun Exposed Lower leg TMOD3 0.07 0.07 enet 22 0.06 6.0e-06 -5.6 5.8 8.8e-09 -0.99 0.03 0.97 TRUE
7 GTEx Thyroid MAPK6 0.04 0.02 lasso 4 0.01 8.8e-02 -4.5 5.1 2.9e-07 -0.92 0.14 0.73 FALSE
8 The Cancer Genome Atlas Lung Adenocarcinoma TMOD2 0.02 0.01 blup 78 0.02 2.3e-03 -4.8 -5.5 2.9e-08 0.98 0.04 0.84 FALSE
9 The Cancer Genome Atlas Pancreatic Adenocarcinoma TMOD2 0.13 0.10 lasso 2 0.07 1.0e-03 5.2 -5.3 1.2e-07 0.73 0.03 0.71 FALSE