[Hub]/) : Traits : Arm fat mass (left) :

chr17:39,993,748-42,998,534

Best TWAS P=3.97e-11 · Best GWAS P=2.07e-11 conditioned to 0.392

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex C17orf65 0.07 0.06 enet 15 0.07 4.5e-09 5.9 -5.2 2.5e-07 -0.80 0.19 0.81 FALSE
2 CommonMind Brain Pre-frontal Cortex MLX 0.03 0.03 enet 12 0.02 6.5e-04 -5.5 -5.5 3.2e-08 -0.08 0.35 0.49 FALSE
3 CommonMind Brain Pre-frontal Cortex TUBG2 0.14 0.25 lasso 3 0.25 1.1e-29 -5.5 -5.5 3.0e-08 -0.07 0.27 0.73 FALSE
4 GTEx Adipose Subcutaneous TUBG2 0.21 0.18 enet 17 0.26 2.1e-21 -5.2 -6.1 8.1e-10 -0.09 0.34 0.66 FALSE
5 GTEx Adipose Subcutaneous HSD17B1 0.06 0.07 enet 5 0.06 6.8e-06 -5.6 -5.6 1.8e-08 -0.07 0.24 0.76 FALSE
6 GTEx Adipose Subcutaneous ASB16-AS1 0.12 0.05 enet 16 0.05 3.7e-05 5.9 -5.2 2.3e-07 -0.67 0.10 0.74 FALSE
7 GTEx Adipose Visceral Omentum ASB16-AS1 0.14 0.12 lasso 5 0.10 9.8e-06 5.7 -5.8 6.7e-09 -0.88 0.20 0.78 FALSE
8 GTEx Artery Tibial TUBG2 0.25 0.22 enet 23 0.23 3.0e-18 -5.6 -5.3 1.1e-07 -0.09 0.25 0.75 FALSE
9 GTEx Artery Tibial HSD17B1 0.12 0.07 lasso 9 0.07 4.4e-06 -5.5 -5.6 1.8e-08 -0.06 0.17 0.83 FALSE
10 GTEx Artery Tibial RP11-400F19.6 0.07 0.01 lasso 5 0.01 3.0e-02 6.3 -6.3 4.0e-10 -0.10 0.00 0.99 FALSE
11 GTEx Brain Caudate basal ganglia TUBG2 0.39 0.24 enet 45 0.25 7.7e-08 -5.5 -6.5 6.3e-11 -0.08 0.10 0.90 FALSE
12 GTEx Brain Cerebellum TUBG2 0.18 0.11 enet 10 0.07 4.0e-03 -5.5 -5.5 3.8e-08 -0.06 0.10 0.82 FALSE
13 GTEx Brain Cerebellum HSD17B1P1 0.17 0.16 lasso 4 0.20 1.7e-06 -5.5 -5.5 3.5e-08 -0.09 0.28 0.60 FALSE
14 GTEx Brain Cerebellum RND2 0.13 0.02 enet 15 0.12 1.7e-04 -2.7 -5.2 1.7e-07 0.04 0.19 0.20 FALSE
15 GTEx Brain Cortex TUBG2 0.36 0.36 enet 15 0.32 1.1e-09 -5.5 -5.7 1.3e-08 -0.06 0.27 0.73 FALSE
16 GTEx Brain Frontal Cortex BA9 TUBG2 0.33 0.26 lasso 4 0.18 1.9e-05 -5.5 -5.6 2.0e-08 -0.07 0.26 0.68 FALSE
17 GTEx Brain Putamen basal ganglia TUBG2 0.17 0.12 lasso 5 0.09 3.7e-03 -5.6 -5.6 1.8e-08 -0.07 0.11 0.50 FALSE
18 GTEx Breast Mammary Tissue TUBG2 0.15 0.06 enet 18 0.08 4.5e-05 -5.2 -5.9 4.1e-09 -0.09 0.37 0.62 FALSE
19 GTEx Breast Mammary Tissue CNTNAP1 0.06 0.03 lasso 2 0.05 9.9e-04 -5.2 5.3 1.1e-07 0.08 0.21 0.40 FALSE
20 GTEx Breast Mammary Tissue (Female) ASB16-AS1 0.08 0.04 lasso 2 0.06 7.9e-03 5.7 -5.8 7.3e-09 -0.87 0.06 0.47 FALSE
21 GTEx Cells Transformed fibroblasts TUBG2 0.16 0.18 lasso 4 0.17 6.5e-13 -5.5 -5.8 6.1e-09 -0.07 0.27 0.73 FALSE
22 GTEx Cells Transformed fibroblasts MLX 0.04 0.03 enet 8 0.00 3.3e-01 -5.5 -5.6 2.6e-08 -0.06 0.17 0.52 FALSE
23 GTEx Cells Transformed fibroblasts ASB16 0.14 0.14 lasso 3 0.12 2.0e-09 5.9 -5.9 2.7e-09 -0.82 0.14 0.86 FALSE
24 GTEx Cells Transformed fibroblasts ASB16-AS1 0.17 0.17 lasso 4 0.16 2.3e-12 5.9 -5.7 1.3e-08 -0.77 0.15 0.85 FALSE
25 GTEx Colon Sigmoid TUBG2 0.16 0.04 lasso 5 0.05 6.7e-03 -5.5 -5.6 1.8e-08 -0.08 0.14 0.51 FALSE
26 GTEx Colon Transverse HSD17B1P1 0.14 0.11 lasso 4 0.09 3.8e-05 -5.2 -5.5 4.6e-08 -0.07 0.27 0.67 FALSE
27 GTEx Colon Transverse HSD17B1 0.15 0.14 lasso 11 0.12 1.7e-06 -5.6 -5.6 2.5e-08 -0.06 0.23 0.76 FALSE
28 GTEx Esophagus Gastroesophageal Junction TUBG2 0.15 0.10 enet 18 0.12 3.7e-05 -5.2 -5.7 1.3e-08 -0.09 0.08 0.83 FALSE
29 GTEx Esophagus Mucosa TUBG2 0.09 0.09 lasso 4 0.11 5.5e-08 -5.6 -6.6 4.0e-11 -0.08 0.02 0.98 TRUE
30 GTEx Esophagus Mucosa HSD17B1P1 0.04 0.06 lasso 5 0.05 1.9e-04 -5.6 -5.6 2.8e-08 -0.06 0.23 0.69 FALSE
31 GTEx Esophagus Mucosa BECN1 0.24 0.08 lasso 4 0.05 5.1e-04 5.7 5.2 1.8e-07 0.11 0.07 0.80 FALSE
32 GTEx Esophagus Mucosa ASB16 0.10 0.10 lasso 4 0.08 8.2e-06 5.9 -5.9 3.1e-09 -0.82 0.14 0.85 FALSE
33 GTEx Esophagus Muscularis TUBG2 0.14 0.16 enet 17 0.06 2.1e-04 -5.5 -5.8 6.0e-09 -0.07 0.27 0.73 FALSE
34 GTEx Esophagus Muscularis NAGLU 0.29 0.09 lasso 5 0.07 6.2e-05 5.7 -5.7 9.9e-09 -0.09 0.13 0.82 FALSE
35 GTEx Esophagus Muscularis HSD17B1 0.08 0.04 lasso 4 0.06 2.2e-04 -5.5 5.5 3.4e-08 0.07 0.22 0.69 FALSE
36 GTEx Esophagus Muscularis RP11-400F19.8 0.17 0.05 lasso 4 0.02 3.9e-02 5.7 -6.1 1.4e-09 -0.04 0.04 0.46 FALSE
37 GTEx Heart Atrial Appendage TUBG2 0.07 0.05 lasso 2 0.02 2.9e-02 -5.5 -5.6 2.0e-08 -0.08 0.11 0.60 FALSE
38 GTEx Heart Left Ventricle RP5-882C2.2 0.14 0.08 lasso 5 0.10 8.1e-06 5.2 -5.6 1.7e-08 -0.78 0.09 0.88 FALSE
39 GTEx Lung TUBG2 0.08 0.02 enet 8 0.04 7.8e-04 -5.6 -5.9 2.9e-09 -0.10 0.07 0.79 FALSE
40 GTEx Lung CNTNAP1 0.06 0.00 enet 16 0.02 1.5e-02 -5.2 5.3 1.4e-07 0.07 0.03 0.81 FALSE
41 GTEx Lung ASB16 0.09 0.09 enet 15 0.07 3.4e-06 5.9 -5.2 1.9e-07 -0.77 0.11 0.89 FALSE
42 GTEx Muscle Skeletal TUBG2 0.12 0.09 lasso 8 0.10 1.1e-09 5.3 -5.3 1.3e-07 -0.09 0.01 0.99 FALSE
43 GTEx Muscle Skeletal ASB16 0.07 0.06 lasso 3 0.06 2.9e-06 4.7 5.3 1.4e-07 0.78 0.22 0.78 FALSE
44 GTEx Nerve Tibial TUBG2 0.26 0.28 enet 39 0.28 2.2e-20 -5.4 -5.9 3.8e-09 -0.10 0.35 0.65 FALSE
45 GTEx Nerve Tibial ASB16 0.12 0.07 lasso 5 0.07 7.5e-06 5.9 -5.9 3.6e-09 -0.85 0.10 0.90 FALSE
46 GTEx Nerve Tibial RP11-400F19.8 0.10 0.03 lasso 3 0.02 8.2e-03 5.7 -5.6 2.3e-08 -0.13 0.10 0.49 FALSE
47 GTEx Nerve Tibial ASB16-AS1 0.17 0.15 lasso 5 0.16 1.4e-11 5.9 -5.5 4.7e-08 -0.79 0.16 0.84 FALSE
48 GTEx Ovary TUBG2 0.20 0.04 enet 17 0.11 1.2e-03 -5.2 -5.3 1.3e-07 -0.07 0.08 0.33 FALSE
49 GTEx Pancreas CNTNAP1 0.13 0.09 lasso 7 0.09 9.1e-05 5.1 6.1 1.1e-09 0.11 0.15 0.63 FALSE
50 GTEx Pancreas FAM134C 0.08 0.04 enet 9 0.03 2.0e-02 4.5 5.8 8.5e-09 0.11 0.09 0.63 FALSE
51 GTEx Pancreas CTD-3193K9.3 0.12 0.07 lasso 5 0.07 5.7e-04 5.1 6.0 2.3e-09 0.11 0.12 0.54 FALSE
52 GTEx Pituitary ASB16-AS1 0.19 0.17 lasso 4 0.22 3.8e-06 3.5 -5.1 2.7e-07 -0.73 0.16 0.62 FALSE
53 GTEx Skin Not Sun Exposed Suprapubic TUBG2 0.15 0.13 lasso 5 0.12 4.0e-07 6.3 -6.5 9.1e-11 -0.09 0.00 1.00 FALSE
54 GTEx Skin Not Sun Exposed Suprapubic TUBG1 0.11 0.01 lasso 6 0.00 1.7e-01 4.7 -5.5 3.0e-08 -0.09 0.04 0.70 FALSE
55 GTEx Skin Sun Exposed Lower leg TUBG2 0.14 0.10 enet 25 0.12 4.9e-10 -5.5 -6.2 7.1e-10 -0.10 0.01 0.99 FALSE
56 GTEx Skin Sun Exposed Lower leg NAGLU 0.08 0.06 enet 9 0.09 5.8e-08 4.5 -5.5 3.9e-08 -0.11 0.37 0.62 FALSE
57 GTEx Skin Sun Exposed Lower leg TUBG1 0.04 0.06 lasso 1 0.05 8.3e-05 -5.6 5.6 1.9e-08 0.06 0.08 0.85 FALSE
58 GTEx Skin Sun Exposed Lower leg ASB16-AS1 0.13 0.09 lasso 5 0.07 2.7e-06 5.5 -5.5 3.1e-08 -0.80 0.20 0.80 FALSE
59 GTEx Stomach HSD17B1P1 0.10 0.04 lasso 3 0.04 6.9e-03 4.7 -6.1 1.1e-09 -0.10 0.08 0.44 FALSE
60 GTEx Testis TUBG1 0.12 0.09 enet 18 0.08 1.8e-04 -5.2 -5.4 5.7e-08 -0.08 0.24 0.72 FALSE
61 GTEx Testis ASB16-AS1 0.35 0.25 lasso 5 0.23 1.0e-10 5.9 -5.9 4.6e-09 -0.82 0.12 0.88 FALSE
62 GTEx Thyroid TUBG2 0.19 0.21 lasso 7 0.20 3.5e-15 -5.4 -5.7 1.2e-08 -0.10 0.41 0.59 FALSE
63 GTEx Thyroid HSD17B1P1 0.04 0.00 enet 9 0.00 2.2e-01 -5.6 -6.5 1.1e-10 -0.07 0.05 0.76 FALSE
64 GTEx Thyroid CNTNAP1 0.06 0.06 enet 12 0.06 3.5e-05 -5.6 5.4 8.2e-08 0.05 0.25 0.71 FALSE
65 GTEx Thyroid RP5-882C2.2 0.10 0.07 lasso 3 0.07 2.9e-06 5.9 -5.8 8.3e-09 -0.80 0.04 0.94 FALSE
66 GTEx Thyroid ASB16-AS1 0.14 0.06 lasso 2 0.04 5.4e-04 5.9 -5.9 3.0e-09 -0.82 0.13 0.78 FALSE
67 GTEx Whole Blood ASB16-AS1 0.14 0.05 lasso 6 0.04 3.1e-04 5.9 -5.9 3.2e-09 -0.83 0.16 0.84 FALSE
68 METSIM Adipose HSD17B1 0.08 0.08 lasso 6 0.06 3.1e-09 -5.5 -5.5 3.5e-08 -0.05 0.25 0.75 FALSE
69 METSIM Adipose TUBG2 0.08 0.09 lasso 6 0.09 5.2e-13 4.7 -5.9 2.9e-09 -0.09 0.57 0.43 FALSE
70 NTR Blood TUBG2 0.01 0.00 blup 247 0.01 4.0e-03 -4.6 6.1 1.0e-09 0.02 0.27 0.49 FALSE
71 The Cancer Genome Atlas Bladder Urothelial Carcinoma C17orf65 0.03 0.00 blup 37 0.01 2.3e-02 5.9 -6.5 1.0e-10 -0.89 0.04 0.73 TRUE
72 The Cancer Genome Atlas Breast Invasive Carcinoma TUBG2 0.02 0.01 lasso 2 0.01 1.7e-02 5.3 -6.0 2.6e-09 -0.09 0.01 0.44 FALSE
73 The Cancer Genome Atlas Colon Adenocarcinoma ASB16 0.05 0.06 blup 40 0.05 4.6e-04 5.7 -6.0 2.5e-09 -0.85 0.08 0.77 FALSE
74 The Cancer Genome Atlas Colon Adenocarcinoma C17orf65 0.05 0.06 blup 38 0.05 4.2e-04 4.7 -6.1 1.4e-09 -0.86 0.10 0.76 FALSE
75 The Cancer Genome Atlas Colon Adenocarcinoma CNTNAP1 0.06 0.05 blup 27 0.03 7.3e-03 -5.2 5.7 1.3e-08 0.11 0.01 0.90 FALSE
76 The Cancer Genome Atlas Colon Adenocarcinoma HSD17B1 0.03 0.01 blup 30 0.01 1.5e-01 -5.6 -5.7 9.8e-09 -0.07 0.04 0.21 FALSE
77 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ASB16 0.02 0.02 blup 39 0.02 3.8e-03 6.3 -6.4 1.6e-10 -0.86 0.02 0.39 FALSE
78 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma C17orf65 0.03 0.01 lasso 10 0.02 3.6e-03 5.6 -6.0 1.7e-09 -0.81 0.05 0.78 FALSE
79 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ASB16 0.02 0.03 blup 40 0.03 1.3e-04 5.5 -6.2 6.3e-10 -0.89 0.13 0.84 FALSE
80 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma HSD17B1 0.06 0.04 lasso 5 0.06 4.0e-07 -5.6 -5.4 6.4e-08 -0.06 0.23 0.72 FALSE
81 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma TUBG2 0.08 0.05 blup 29 0.07 3.5e-08 -5.5 -5.5 3.8e-08 -0.08 0.01 0.99 FALSE
82 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma HSD17B1 0.05 0.05 enet 25 0.04 1.4e-03 -5.6 -5.3 1.5e-07 -0.04 0.11 0.63 FALSE
83 The Cancer Genome Atlas Brain Lower Grade Glioma ASB16 0.03 0.03 lasso 3 0.03 3.2e-04 5.8 -5.8 7.9e-09 -0.88 0.09 0.84 FALSE
84 The Cancer Genome Atlas Brain Lower Grade Glioma C17orf65 0.04 0.04 blup 37 0.03 1.4e-04 5.9 -5.7 9.0e-09 -0.83 0.14 0.83 FALSE
85 The Cancer Genome Atlas Brain Lower Grade Glioma HSD17B1 0.30 0.05 enet 14 0.06 2.8e-07 -5.5 -6.2 4.5e-10 -0.09 0.21 0.78 FALSE
86 The Cancer Genome Atlas Brain Lower Grade Glioma TUBG2 0.07 0.12 enet 14 0.12 5.9e-13 -5.5 -5.6 2.8e-08 -0.07 0.01 0.99 FALSE
87 The Cancer Genome Atlas Lung Adenocarcinoma ASB16 0.02 0.02 lasso 4 0.01 6.3e-03 5.9 -5.5 4.6e-08 -0.81 0.06 0.45 FALSE
88 The Cancer Genome Atlas Lung Adenocarcinoma CNTNAP1 0.06 0.05 lasso 1 0.04 6.8e-06 -5.2 5.2 1.6e-07 0.08 0.02 0.98 FALSE
89 The Cancer Genome Atlas Lung Adenocarcinoma RND2 0.08 0.00 enet 16 0.02 3.5e-03 -3.8 5.3 1.1e-07 0.01 0.00 0.01 TRUE
90 The Cancer Genome Atlas Lung Adenocarcinoma TUBG2 0.07 0.01 enet 7 0.02 2.2e-03 5.3 -5.9 3.9e-09 -0.12 0.01 0.48 FALSE
91 The Cancer Genome Atlas Lung Squamous Cell Carcinoma ASB16 0.04 0.04 lasso 4 0.03 1.8e-04 6.4 -6.3 2.2e-10 -0.87 0.03 0.94 FALSE
92 The Cancer Genome Atlas Lung Squamous Cell Carcinoma C17orf65 0.07 0.05 lasso 6 0.05 3.1e-06 5.9 -5.6 1.9e-08 -0.73 0.07 0.92 FALSE
93 The Cancer Genome Atlas Lung Squamous Cell Carcinoma PSMC3IP 0.02 0.02 blup 33 0.02 9.8e-04 -5.5 -6.4 1.4e-10 -0.08 0.03 0.77 FALSE
94 The Cancer Genome Atlas Lung Squamous Cell Carcinoma TUBG2 0.02 0.01 blup 29 0.02 4.5e-03 3.7 -5.6 1.9e-08 -0.08 0.01 0.62 FALSE
95 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma C17orf65 0.04 0.03 blup 39 0.03 2.7e-03 6.3 -5.9 4.5e-09 -0.87 0.02 0.81 FALSE
96 The Cancer Genome Atlas Pancreatic Adenocarcinoma C17orf65 0.09 0.02 blup 38 0.04 8.0e-03 5.9 -5.3 1.3e-07 -0.76 0.02 0.33 FALSE
97 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma C17orf65 0.09 0.09 enet 8 0.08 2.9e-04 5.7 -6.1 8.9e-10 -0.88 0.03 0.91 FALSE
98 The Cancer Genome Atlas Prostate Adenocarcinoma CNTNAP1 0.06 0.04 blup 27 0.04 8.9e-05 -5.2 5.6 1.9e-08 0.11 0.02 0.97 FALSE
99 The Cancer Genome Atlas Prostate Adenocarcinoma HSD17B1 0.02 0.03 blup 30 0.03 4.0e-04 -5.4 -6.0 2.3e-09 -0.09 0.22 0.58 FALSE
100 The Cancer Genome Atlas Prostate Adenocarcinoma TUBG2 0.04 0.02 blup 29 0.02 1.5e-03 -5.5 -6.1 8.7e-10 -0.07 0.01 0.86 FALSE
101 The Cancer Genome Atlas Skin Cutaneous Melanoma C17orf65 0.15 0.05 blup 37 0.09 1.7e-03 5.9 -5.4 7.1e-08 -0.81 0.02 0.63 FALSE
102 The Cancer Genome Atlas Testicular Germ Cell Tumors C17orf65 0.07 0.02 blup 38 0.04 1.1e-02 5.8 -6.2 4.3e-10 -0.89 0.02 0.23 FALSE
103 The Cancer Genome Atlas Thyroid Carcinoma C17orf65 0.03 0.03 lasso 7 0.03 3.8e-04 5.9 -6.2 4.9e-10 -0.86 0.04 0.88 FALSE
104 The Cancer Genome Atlas Thyroid Carcinoma CNTNAP1 0.04 0.03 blup 27 0.05 2.7e-05 -5.0 5.7 1.3e-08 0.10 0.03 0.95 FALSE
105 The Cancer Genome Atlas Thyroid Carcinoma HSD17B1 0.05 0.07 blup 29 0.07 2.3e-07 -5.2 -6.2 5.5e-10 -0.10 0.35 0.65 FALSE
106 The Cancer Genome Atlas Thyroid Carcinoma TUBG2 0.20 0.13 blup 29 0.17 1.7e-16 5.3 -5.8 7.0e-09 -0.07 0.02 0.98 FALSE