[Hub]/) : Traits : Arm fat mass (left) : ← →

chr17:39,993,748-42,998,534

Best TWAS P=3.97e-11 · Best GWAS P=2.07e-11 conditioned to 0.392

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
29	GTEx	Esophagus Mucosa	TUBG2	0.09	0.09	lasso	4	0.11	5.5e-08	-5.6	-6.6	4.0e-11	-0.08	0.02	0.98	TRUE
71	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	C17orf65	0.03	0.00	blup	37	0.01	2.3e-02	5.9	-6.5	1.0e-10	-0.89	0.04	0.73	TRUE
89	The Cancer Genome Atlas	Lung Adenocarcinoma	RND2	0.08	0.00	enet	16	0.02	3.5e-03	-3.8	5.3	1.1e-07	0.01	0.00	0.01	TRUE
11	GTEx	Brain Caudate basal ganglia	TUBG2	0.39	0.24	enet	45	0.25	7.7e-08	-5.5	-6.5	6.3e-11	-0.08	0.10	0.90	FALSE
53	GTEx	Skin Not Sun Exposed Suprapubic	TUBG2	0.15	0.13	lasso	5	0.12	4.0e-07	6.3	-6.5	9.1e-11	-0.09	0.00	1.00	FALSE
63	GTEx	Thyroid	HSD17B1P1	0.04	0.00	enet	9	0.00	2.2e-01	-5.6	-6.5	1.1e-10	-0.07	0.05	0.76	FALSE
93	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	PSMC3IP	0.02	0.02	blup	33	0.02	9.8e-04	-5.5	-6.4	1.4e-10	-0.08	0.03	0.77	FALSE
77	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ASB16	0.02	0.02	blup	39	0.02	3.8e-03	6.3	-6.4	1.6e-10	-0.86	0.02	0.39	FALSE
91	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	ASB16	0.04	0.04	lasso	4	0.03	1.8e-04	6.4	-6.3	2.2e-10	-0.87	0.03	0.94	FALSE
10	GTEx	Artery Tibial	RP11-400F19.6	0.07	0.01	lasso	5	0.01	3.0e-02	6.3	-6.3	4.0e-10	-0.10	0.00	0.99	FALSE
102	The Cancer Genome Atlas	Testicular Germ Cell Tumors	C17orf65	0.07	0.02	blup	38	0.04	1.1e-02	5.8	-6.2	4.3e-10	-0.89	0.02	0.23	FALSE
85	The Cancer Genome Atlas	Brain Lower Grade Glioma	HSD17B1	0.30	0.05	enet	14	0.06	2.8e-07	-5.5	-6.2	4.5e-10	-0.09	0.21	0.78	FALSE
103	The Cancer Genome Atlas	Thyroid Carcinoma	C17orf65	0.03	0.03	lasso	7	0.03	3.8e-04	5.9	-6.2	4.9e-10	-0.86	0.04	0.88	FALSE
105	The Cancer Genome Atlas	Thyroid Carcinoma	HSD17B1	0.05	0.07	blup	29	0.07	2.3e-07	-5.2	-6.2	5.5e-10	-0.10	0.35	0.65	FALSE
79	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ASB16	0.02	0.03	blup	40	0.03	1.3e-04	5.5	-6.2	6.3e-10	-0.89	0.13	0.84	FALSE
55	GTEx	Skin Sun Exposed Lower leg	TUBG2	0.14	0.10	enet	25	0.12	4.9e-10	-5.5	-6.2	7.1e-10	-0.10	0.01	0.99	FALSE
4	GTEx	Adipose Subcutaneous	TUBG2	0.21	0.18	enet	17	0.26	2.1e-21	-5.2	-6.1	8.1e-10	-0.09	0.34	0.66	FALSE
100	The Cancer Genome Atlas	Prostate Adenocarcinoma	TUBG2	0.04	0.02	blup	29	0.02	1.5e-03	-5.5	-6.1	8.7e-10	-0.07	0.01	0.86	FALSE
97	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	C17orf65	0.09	0.09	enet	8	0.08	2.9e-04	5.7	-6.1	8.9e-10	-0.88	0.03	0.91	FALSE
70	NTR	Blood	TUBG2	0.01	0.00	blup	247	0.01	4.0e-03	-4.6	6.1	1.0e-09	0.02	0.27	0.49	FALSE
49	GTEx	Pancreas	CNTNAP1	0.13	0.09	lasso	7	0.09	9.1e-05	5.1	6.1	1.1e-09	0.11	0.15	0.63	FALSE
59	GTEx	Stomach	HSD17B1P1	0.10	0.04	lasso	3	0.04	6.9e-03	4.7	-6.1	1.1e-09	-0.10	0.08	0.44	FALSE
36	GTEx	Esophagus Muscularis	RP11-400F19.8	0.17	0.05	lasso	4	0.02	3.9e-02	5.7	-6.1	1.4e-09	-0.04	0.04	0.46	FALSE
74	The Cancer Genome Atlas	Colon Adenocarcinoma	C17orf65	0.05	0.06	blup	38	0.05	4.2e-04	4.7	-6.1	1.4e-09	-0.86	0.10	0.76	FALSE
78	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C17orf65	0.03	0.01	lasso	10	0.02	3.6e-03	5.6	-6.0	1.7e-09	-0.81	0.05	0.78	FALSE
51	GTEx	Pancreas	CTD-3193K9.3	0.12	0.07	lasso	5	0.07	5.7e-04	5.1	6.0	2.3e-09	0.11	0.12	0.54	FALSE
99	The Cancer Genome Atlas	Prostate Adenocarcinoma	HSD17B1	0.02	0.03	blup	30	0.03	4.0e-04	-5.4	-6.0	2.3e-09	-0.09	0.22	0.58	FALSE
73	The Cancer Genome Atlas	Colon Adenocarcinoma	ASB16	0.05	0.06	blup	40	0.05	4.6e-04	5.7	-6.0	2.5e-09	-0.85	0.08	0.77	FALSE
72	The Cancer Genome Atlas	Breast Invasive Carcinoma	TUBG2	0.02	0.01	lasso	2	0.01	1.7e-02	5.3	-6.0	2.6e-09	-0.09	0.01	0.44	FALSE
23	GTEx	Cells Transformed fibroblasts	ASB16	0.14	0.14	lasso	3	0.12	2.0e-09	5.9	-5.9	2.7e-09	-0.82	0.14	0.86	FALSE
39	GTEx	Lung	TUBG2	0.08	0.02	enet	8	0.04	7.8e-04	-5.6	-5.9	2.9e-09	-0.10	0.07	0.79	FALSE
69	METSIM	Adipose	TUBG2	0.08	0.09	lasso	6	0.09	5.2e-13	4.7	-5.9	2.9e-09	-0.09	0.57	0.43	FALSE
66	GTEx	Thyroid	ASB16-AS1	0.14	0.06	lasso	2	0.04	5.4e-04	5.9	-5.9	3.0e-09	-0.82	0.13	0.78	FALSE
32	GTEx	Esophagus Mucosa	ASB16	0.10	0.10	lasso	4	0.08	8.2e-06	5.9	-5.9	3.1e-09	-0.82	0.14	0.85	FALSE
67	GTEx	Whole Blood	ASB16-AS1	0.14	0.05	lasso	6	0.04	3.1e-04	5.9	-5.9	3.2e-09	-0.83	0.16	0.84	FALSE
45	GTEx	Nerve Tibial	ASB16	0.12	0.07	lasso	5	0.07	7.5e-06	5.9	-5.9	3.6e-09	-0.85	0.10	0.90	FALSE
44	GTEx	Nerve Tibial	TUBG2	0.26	0.28	enet	39	0.28	2.2e-20	-5.4	-5.9	3.8e-09	-0.10	0.35	0.65	FALSE
90	The Cancer Genome Atlas	Lung Adenocarcinoma	TUBG2	0.07	0.01	enet	7	0.02	2.2e-03	5.3	-5.9	3.9e-09	-0.12	0.01	0.48	FALSE
18	GTEx	Breast Mammary Tissue	TUBG2	0.15	0.06	enet	18	0.08	4.5e-05	-5.2	-5.9	4.1e-09	-0.09	0.37	0.62	FALSE
95	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C17orf65	0.04	0.03	blup	39	0.03	2.7e-03	6.3	-5.9	4.5e-09	-0.87	0.02	0.81	FALSE
61	GTEx	Testis	ASB16-AS1	0.35	0.25	lasso	5	0.23	1.0e-10	5.9	-5.9	4.6e-09	-0.82	0.12	0.88	FALSE
33	GTEx	Esophagus Muscularis	TUBG2	0.14	0.16	enet	17	0.06	2.1e-04	-5.5	-5.8	6.0e-09	-0.07	0.27	0.73	FALSE
21	GTEx	Cells Transformed fibroblasts	TUBG2	0.16	0.18	lasso	4	0.17	6.5e-13	-5.5	-5.8	6.1e-09	-0.07	0.27	0.73	FALSE
7	GTEx	Adipose Visceral Omentum	ASB16-AS1	0.14	0.12	lasso	5	0.10	9.8e-06	5.7	-5.8	6.7e-09	-0.88	0.20	0.78	FALSE
106	The Cancer Genome Atlas	Thyroid Carcinoma	TUBG2	0.20	0.13	blup	29	0.17	1.7e-16	5.3	-5.8	7.0e-09	-0.07	0.02	0.98	FALSE
20	GTEx	Breast Mammary Tissue (Female)	ASB16-AS1	0.08	0.04	lasso	2	0.06	7.9e-03	5.7	-5.8	7.3e-09	-0.87	0.06	0.47	FALSE
83	The Cancer Genome Atlas	Brain Lower Grade Glioma	ASB16	0.03	0.03	lasso	3	0.03	3.2e-04	5.8	-5.8	7.9e-09	-0.88	0.09	0.84	FALSE
65	GTEx	Thyroid	RP5-882C2.2	0.10	0.07	lasso	3	0.07	2.9e-06	5.9	-5.8	8.3e-09	-0.80	0.04	0.94	FALSE
50	GTEx	Pancreas	FAM134C	0.08	0.04	enet	9	0.03	2.0e-02	4.5	5.8	8.5e-09	0.11	0.09	0.63	FALSE
84	The Cancer Genome Atlas	Brain Lower Grade Glioma	C17orf65	0.04	0.04	blup	37	0.03	1.4e-04	5.9	-5.7	9.0e-09	-0.83	0.14	0.83	FALSE
76	The Cancer Genome Atlas	Colon Adenocarcinoma	HSD17B1	0.03	0.01	blup	30	0.01	1.5e-01	-5.6	-5.7	9.8e-09	-0.07	0.04	0.21	FALSE
34	GTEx	Esophagus Muscularis	NAGLU	0.29	0.09	lasso	5	0.07	6.2e-05	5.7	-5.7	9.9e-09	-0.09	0.13	0.82	FALSE
62	GTEx	Thyroid	TUBG2	0.19	0.21	lasso	7	0.20	3.5e-15	-5.4	-5.7	1.2e-08	-0.10	0.41	0.59	FALSE
15	GTEx	Brain Cortex	TUBG2	0.36	0.36	enet	15	0.32	1.1e-09	-5.5	-5.7	1.3e-08	-0.06	0.27	0.73	FALSE
24	GTEx	Cells Transformed fibroblasts	ASB16-AS1	0.17	0.17	lasso	4	0.16	2.3e-12	5.9	-5.7	1.3e-08	-0.77	0.15	0.85	FALSE
28	GTEx	Esophagus Gastroesophageal Junction	TUBG2	0.15	0.10	enet	18	0.12	3.7e-05	-5.2	-5.7	1.3e-08	-0.09	0.08	0.83	FALSE
75	The Cancer Genome Atlas	Colon Adenocarcinoma	CNTNAP1	0.06	0.05	blup	27	0.03	7.3e-03	-5.2	5.7	1.3e-08	0.11	0.01	0.90	FALSE
104	The Cancer Genome Atlas	Thyroid Carcinoma	CNTNAP1	0.04	0.03	blup	27	0.05	2.7e-05	-5.0	5.7	1.3e-08	0.10	0.03	0.95	FALSE
38	GTEx	Heart Left Ventricle	RP5-882C2.2	0.14	0.08	lasso	5	0.10	8.1e-06	5.2	-5.6	1.7e-08	-0.78	0.09	0.88	FALSE
5	GTEx	Adipose Subcutaneous	HSD17B1	0.06	0.07	enet	5	0.06	6.8e-06	-5.6	-5.6	1.8e-08	-0.07	0.24	0.76	FALSE
9	GTEx	Artery Tibial	HSD17B1	0.12	0.07	lasso	9	0.07	4.4e-06	-5.5	-5.6	1.8e-08	-0.06	0.17	0.83	FALSE
17	GTEx	Brain Putamen basal ganglia	TUBG2	0.17	0.12	lasso	5	0.09	3.7e-03	-5.6	-5.6	1.8e-08	-0.07	0.11	0.50	FALSE
25	GTEx	Colon Sigmoid	TUBG2	0.16	0.04	lasso	5	0.05	6.7e-03	-5.5	-5.6	1.8e-08	-0.08	0.14	0.51	FALSE
57	GTEx	Skin Sun Exposed Lower leg	TUBG1	0.04	0.06	lasso	1	0.05	8.3e-05	-5.6	5.6	1.9e-08	0.06	0.08	0.85	FALSE
92	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C17orf65	0.07	0.05	lasso	6	0.05	3.1e-06	5.9	-5.6	1.9e-08	-0.73	0.07	0.92	FALSE
94	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	TUBG2	0.02	0.01	blup	29	0.02	4.5e-03	3.7	-5.6	1.9e-08	-0.08	0.01	0.62	FALSE
98	The Cancer Genome Atlas	Prostate Adenocarcinoma	CNTNAP1	0.06	0.04	blup	27	0.04	8.9e-05	-5.2	5.6	1.9e-08	0.11	0.02	0.97	FALSE
16	GTEx	Brain Frontal Cortex BA9	TUBG2	0.33	0.26	lasso	4	0.18	1.9e-05	-5.5	-5.6	2.0e-08	-0.07	0.26	0.68	FALSE
37	GTEx	Heart Atrial Appendage	TUBG2	0.07	0.05	lasso	2	0.02	2.9e-02	-5.5	-5.6	2.0e-08	-0.08	0.11	0.60	FALSE
46	GTEx	Nerve Tibial	RP11-400F19.8	0.10	0.03	lasso	3	0.02	8.2e-03	5.7	-5.6	2.3e-08	-0.13	0.10	0.49	FALSE
27	GTEx	Colon Transverse	HSD17B1	0.15	0.14	lasso	11	0.12	1.7e-06	-5.6	-5.6	2.5e-08	-0.06	0.23	0.76	FALSE
22	GTEx	Cells Transformed fibroblasts	MLX	0.04	0.03	enet	8	0.00	3.3e-01	-5.5	-5.6	2.6e-08	-0.06	0.17	0.52	FALSE
30	GTEx	Esophagus Mucosa	HSD17B1P1	0.04	0.06	lasso	5	0.05	1.9e-04	-5.6	-5.6	2.8e-08	-0.06	0.23	0.69	FALSE
86	The Cancer Genome Atlas	Brain Lower Grade Glioma	TUBG2	0.07	0.12	enet	14	0.12	5.9e-13	-5.5	-5.6	2.8e-08	-0.07	0.01	0.99	FALSE
3	CommonMind	Brain Pre-frontal Cortex	TUBG2	0.14	0.25	lasso	3	0.25	1.1e-29	-5.5	-5.5	3.0e-08	-0.07	0.27	0.73	FALSE
54	GTEx	Skin Not Sun Exposed Suprapubic	TUBG1	0.11	0.01	lasso	6	0.00	1.7e-01	4.7	-5.5	3.0e-08	-0.09	0.04	0.70	FALSE
58	GTEx	Skin Sun Exposed Lower leg	ASB16-AS1	0.13	0.09	lasso	5	0.07	2.7e-06	5.5	-5.5	3.1e-08	-0.80	0.20	0.80	FALSE
2	CommonMind	Brain Pre-frontal Cortex	MLX	0.03	0.03	enet	12	0.02	6.5e-04	-5.5	-5.5	3.2e-08	-0.08	0.35	0.49	FALSE
35	GTEx	Esophagus Muscularis	HSD17B1	0.08	0.04	lasso	4	0.06	2.2e-04	-5.5	5.5	3.4e-08	0.07	0.22	0.69	FALSE
13	GTEx	Brain Cerebellum	HSD17B1P1	0.17	0.16	lasso	4	0.20	1.7e-06	-5.5	-5.5	3.5e-08	-0.09	0.28	0.60	FALSE
68	METSIM	Adipose	HSD17B1	0.08	0.08	lasso	6	0.06	3.1e-09	-5.5	-5.5	3.5e-08	-0.05	0.25	0.75	FALSE
12	GTEx	Brain Cerebellum	TUBG2	0.18	0.11	enet	10	0.07	4.0e-03	-5.5	-5.5	3.8e-08	-0.06	0.10	0.82	FALSE
81	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TUBG2	0.08	0.05	blup	29	0.07	3.5e-08	-5.5	-5.5	3.8e-08	-0.08	0.01	0.99	FALSE
56	GTEx	Skin Sun Exposed Lower leg	NAGLU	0.08	0.06	enet	9	0.09	5.8e-08	4.5	-5.5	3.9e-08	-0.11	0.37	0.62	FALSE
26	GTEx	Colon Transverse	HSD17B1P1	0.14	0.11	lasso	4	0.09	3.8e-05	-5.2	-5.5	4.6e-08	-0.07	0.27	0.67	FALSE
87	The Cancer Genome Atlas	Lung Adenocarcinoma	ASB16	0.02	0.02	lasso	4	0.01	6.3e-03	5.9	-5.5	4.6e-08	-0.81	0.06	0.45	FALSE
47	GTEx	Nerve Tibial	ASB16-AS1	0.17	0.15	lasso	5	0.16	1.4e-11	5.9	-5.5	4.7e-08	-0.79	0.16	0.84	FALSE
60	GTEx	Testis	TUBG1	0.12	0.09	enet	18	0.08	1.8e-04	-5.2	-5.4	5.7e-08	-0.08	0.24	0.72	FALSE
80	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	HSD17B1	0.06	0.04	lasso	5	0.06	4.0e-07	-5.6	-5.4	6.4e-08	-0.06	0.23	0.72	FALSE
101	The Cancer Genome Atlas	Skin Cutaneous Melanoma	C17orf65	0.15	0.05	blup	37	0.09	1.7e-03	5.9	-5.4	7.1e-08	-0.81	0.02	0.63	FALSE
64	GTEx	Thyroid	CNTNAP1	0.06	0.06	enet	12	0.06	3.5e-05	-5.6	5.4	8.2e-08	0.05	0.25	0.71	FALSE
8	GTEx	Artery Tibial	TUBG2	0.25	0.22	enet	23	0.23	3.0e-18	-5.6	-5.3	1.1e-07	-0.09	0.25	0.75	FALSE
19	GTEx	Breast Mammary Tissue	CNTNAP1	0.06	0.03	lasso	2	0.05	9.9e-04	-5.2	5.3	1.1e-07	0.08	0.21	0.40	FALSE
42	GTEx	Muscle Skeletal	TUBG2	0.12	0.09	lasso	8	0.10	1.1e-09	5.3	-5.3	1.3e-07	-0.09	0.01	0.99	FALSE
48	GTEx	Ovary	TUBG2	0.20	0.04	enet	17	0.11	1.2e-03	-5.2	-5.3	1.3e-07	-0.07	0.08	0.33	FALSE
96	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	C17orf65	0.09	0.02	blup	38	0.04	8.0e-03	5.9	-5.3	1.3e-07	-0.76	0.02	0.33	FALSE
40	GTEx	Lung	CNTNAP1	0.06	0.00	enet	16	0.02	1.5e-02	-5.2	5.3	1.4e-07	0.07	0.03	0.81	FALSE
43	GTEx	Muscle Skeletal	ASB16	0.07	0.06	lasso	3	0.06	2.9e-06	4.7	5.3	1.4e-07	0.78	0.22	0.78	FALSE
82	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	HSD17B1	0.05	0.05	enet	25	0.04	1.4e-03	-5.6	-5.3	1.5e-07	-0.04	0.11	0.63	FALSE
88	The Cancer Genome Atlas	Lung Adenocarcinoma	CNTNAP1	0.06	0.05	lasso	1	0.04	6.8e-06	-5.2	5.2	1.6e-07	0.08	0.02	0.98	FALSE
14	GTEx	Brain Cerebellum	RND2	0.13	0.02	enet	15	0.12	1.7e-04	-2.7	-5.2	1.7e-07	0.04	0.19	0.20	FALSE
31	GTEx	Esophagus Mucosa	BECN1	0.24	0.08	lasso	4	0.05	5.1e-04	5.7	5.2	1.8e-07	0.11	0.07	0.80	FALSE
41	GTEx	Lung	ASB16	0.09	0.09	enet	15	0.07	3.4e-06	5.9	-5.2	1.9e-07	-0.77	0.11	0.89	FALSE
6	GTEx	Adipose Subcutaneous	ASB16-AS1	0.12	0.05	enet	16	0.05	3.7e-05	5.9	-5.2	2.3e-07	-0.67	0.10	0.74	FALSE
1	CommonMind	Brain Pre-frontal Cortex	C17orf65	0.07	0.06	enet	15	0.07	4.5e-09	5.9	-5.2	2.5e-07	-0.80	0.19	0.81	FALSE
52	GTEx	Pituitary	ASB16-AS1	0.19	0.17	lasso	4	0.22	3.8e-06	3.5	-5.1	2.7e-07	-0.73	0.16	0.62	FALSE