[Hub]/) : Traits : Arm fat mass (left) : ← →

chr2:24,324,172-26,088,769

Best TWAS P=4.12e-44 · Best GWAS P=3.17e-36 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ADCY3	0.16	0.12	lasso	10	0.14	3.2e-17	12.2	-13.9	4.1e-44	-0.87	0.01	0.99	TRUE
4	GTEx	Adipose Subcutaneous	RP11-443B20.1	0.04	0.00	enet	10	0.00	1.2e-01	7.1	9.2	5.5e-20	0.81	0.04	0.90	TRUE
9	GTEx	Cells EBV-transformed lymphocytes	ADCY3	0.25	0.23	enet	10	0.12	9.2e-05	11.0	-8.8	1.2e-18	-0.84	0.02	0.97	TRUE
22	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	POMC	0.06	0.00	enet	12	0.03	9.3e-05	-3.0	-7.3	3.9e-13	-0.27	0.01	0.41	TRUE
21	The Cancer Genome Atlas	Breast Invasive Carcinoma	POMC	0.08	0.05	lasso	3	0.06	2.6e-12	-3.0	-6.9	5.3e-12	-0.20	0.97	0.03	TRUE
28	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	POMC	0.19	0.01	blup	38	0.05	1.5e-04	-8.0	-6.8	7.3e-12	-0.33	0.01	0.56	TRUE
31	The Cancer Genome Atlas	Stomach Adenocarcinoma	POMC	0.14	0.00	blup	40	0.02	2.2e-02	-3.6	-5.7	1.0e-08	-0.14	0.01	0.18	TRUE
24	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	POMC	0.16	0.05	blup	39	0.11	2.4e-12	-8.0	-5.2	2.7e-07	-0.22	1.00	0.00	TRUE
11	GTEx	Nerve Tibial	ADCY3	0.09	0.05	enet	6	0.03	2.2e-03	10.7	-12.9	5.5e-38	-0.91	0.02	0.98	FALSE
15	GTEx	Whole Blood	RP11-443B20.1	0.21	0.17	enet	32	0.20	1.8e-18	10.8	12.7	4.2e-37	0.86	0.79	0.21	FALSE
12	GTEx	Nerve Tibial	RP11-443B20.1	0.07	0.03	enet	6	0.02	1.1e-02	10.7	-12.6	2.3e-36	-0.81	0.03	0.96	FALSE
14	GTEx	Whole Blood	ADCY3	0.23	0.24	enet	24	0.27	5.5e-25	11.1	12.2	2.0e-34	0.86	1.00	0.00	FALSE
17	ROSMAP	Brain Pre-frontal Cortex	ADCY3	0.17	0.26	enet	32	0.26	6.8e-33	11.1	-12.2	2.3e-34	-0.89	0.80	0.20	FALSE
7	GTEx	Artery Tibial	ADCY3	0.21	0.14	lasso	6	0.15	4.3e-12	10.7	11.9	2.1e-32	0.69	0.98	0.02	FALSE
10	GTEx	Cells EBV-transformed lymphocytes	RP11-443B20.1	0.13	0.13	enet	9	0.05	9.2e-03	11.0	-11.3	9.1e-30	-0.93	0.01	0.97	FALSE
13	GTEx	Whole Blood	DNAJC27	0.08	0.10	lasso	1	0.10	2.2e-09	10.8	10.8	3.8e-27	0.80	0.91	0.09	FALSE
8	GTEx	Artery Tibial	RP11-443B20.1	0.17	0.08	enet	40	0.09	8.2e-08	10.7	10.5	1.1e-25	0.59	0.43	0.53	FALSE
25	The Cancer Genome Atlas	Brain Lower Grade Glioma	ADCY3	0.03	0.02	blup	81	0.02	7.1e-04	6.6	-10.5	1.1e-25	-0.87	0.04	0.93	FALSE
3	GTEx	Adipose Subcutaneous	ADCY3	0.07	0.04	lasso	6	0.01	3.2e-02	11.0	10.4	1.6e-25	0.86	0.07	0.91	FALSE
23	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	EFR3B	0.03	0.05	lasso	1	0.04	1.9e-05	-9.6	-9.6	7.8e-22	-0.67	0.56	0.06	FALSE
2	CommonMind	Brain Pre-frontal Cortex	CENPO	0.07	0.03	bslmm	322	0.03	7.0e-05	7.4	-8.9	5.5e-19	-0.49	0.46	0.29	FALSE
27	The Cancer Genome Atlas	Lung Adenocarcinoma	POMC	0.14	0.04	enet	7	0.08	5.3e-10	-3.0	-7.9	2.0e-15	-0.22	0.38	0.62	FALSE
30	The Cancer Genome Atlas	Prostate Adenocarcinoma	POMC	0.11	0.08	enet	7	0.09	1.6e-09	-3.0	-7.8	5.4e-15	-0.24	0.92	0.06	FALSE
19	YFS	Blood	ADCY3	0.07	0.02	bslmm	343	0.04	7.3e-14	12.5	-7.7	1.2e-14	-0.61	0.00	1.00	FALSE
29	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	POMC	0.22	0.05	blup	37	0.03	2.1e-02	-3.6	-7.6	3.8e-14	-0.12	0.01	0.29	FALSE
16	METSIM	Adipose	EFR3B	0.04	0.00	bslmm	357	0.00	9.7e-02	-1.3	-7.4	1.2e-13	-0.37	0.06	0.08	FALSE
20	YFS	Blood	POMC	0.35	0.05	enet	71	0.19	5.7e-59	-8.0	-7.3	2.7e-13	-0.31	1.00	0.00	FALSE
26	The Cancer Genome Atlas	Lung Adenocarcinoma	DNAJC27	0.05	0.01	blup	46	0.04	3.2e-05	3.5	-6.7	1.8e-11	-0.55	0.34	0.60	FALSE
5	GTEx	Adrenal Gland	PTRHD1	0.32	0.28	lasso	3	0.26	8.3e-10	-5.2	5.6	2.1e-08	0.41	0.98	0.00	FALSE
6	GTEx	Artery Coronary	DNAJC27	0.12	0.03	lasso	7	0.00	2.4e-01	3.5	5.5	3.4e-08	0.46	0.14	0.22	FALSE
18	ROSMAP	Brain Pre-frontal Cortex	CENPO	0.08	0.04	enet	5	0.05	2.6e-07	-4.5	-5.5	4.6e-08	-0.36	1.00	0.00	FALSE