[Hub]/) : Traits : Arm fat-free mass (left) : ← →

chr5:136,723,696-140,767,031

Best TWAS P=6.18e-14 · Best GWAS P=8.11e-18 conditioned to 1.33e-07

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
20	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	UBE2D2	0.05	0.02	enet	6	0.03	4.4e-04	5.0	7.5	6.2e-14	0.76	0.01	0.97	TRUE
14	ROSMAP	Brain Pre-frontal Cortex	WNT8A	0.05	0.01	blup	300	0.03	1.0e-04	-2.0	-6.8	1.2e-11	0.05	0.10	0.84	TRUE
10	GTEx	Nerve Tibial	HARS	0.07	0.01	enet	16	0.04	1.1e-03	-4.4	5.4	5.8e-08	-0.03	0.12	0.74	TRUE
6	GTEx	Esophagus Gastroesophageal Junction	DNAJC18	0.17	0.01	lasso	10	0.04	2.0e-02	4.2	7.2	8.2e-13	0.77	0.03	0.83	FALSE
16	YFS	Blood	CXXC5	0.01	0.00	bslmm	244	0.01	2.6e-03	8.6	-6.7	2.3e-11	-0.67	0.00	0.95	FALSE
21	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	BRD8	0.12	0.07	lasso	4	0.05	1.2e-03	6.7	-6.4	1.3e-10	0.03	0.00	0.98	FALSE
1	CommonMind	Brain Pre-frontal Cortex	DNAJC18	0.09	0.10	bslmm	260	0.10	2.5e-12	3.7	6.0	1.9e-09	0.41	1.00	0.00	FALSE
13	GTEx	Vagina	PURA	0.52	0.05	enet	51	0.09	3.6e-03	5.2	-6.0	2.2e-09	-0.44	0.06	0.10	FALSE
3	GTEx	Cells EBV-transformed lymphocytes	DNAJC18	0.26	0.09	lasso	2	0.12	9.7e-05	4.2	5.9	3.3e-09	0.49	0.11	0.55	FALSE
5	GTEx	Colon Transverse	DNAJC18	0.37	-0.01	lasso	5	0.01	1.1e-01	4.2	5.8	5.1e-09	0.39	0.06	0.06	FALSE
8	GTEx	Esophagus Muscularis	DNAJC18	0.22	0.10	lasso	6	0.13	3.2e-08	4.2	5.7	1.1e-08	0.40	0.56	0.10	FALSE
7	GTEx	Esophagus Mucosa	TMEM173	0.10	0.03	enet	20	0.10	1.8e-07	8.6	-5.6	2.3e-08	-0.60	0.01	0.96	FALSE
2	CommonMind	Brain Pre-frontal Cortex	FAM53C	0.05	0.02	bslmm	291	0.03	4.1e-04	7.2	5.6	2.4e-08	-0.06	0.03	0.92	FALSE
15	ROSMAP	Brain Pre-frontal Cortex	KDM3B	0.07	0.01	blup	307	0.03	1.0e-04	4.8	-5.5	4.3e-08	-0.03	0.12	0.81	FALSE
18	The Cancer Genome Atlas	Breast Invasive Carcinoma	TMEM173	0.02	0.03	blup	7	0.03	4.6e-07	4.5	-5.4	6.0e-08	-0.40	0.07	0.92	FALSE
12	GTEx	Spleen	DNAJC18	0.30	0.13	lasso	5	0.20	6.5e-06	4.2	5.3	8.6e-08	0.47	0.14	0.52	FALSE
9	GTEx	Esophagus Muscularis	TMEM173	0.24	0.00	lasso	6	0.06	1.5e-04	4.2	-5.3	1.1e-07	-0.40	0.76	0.07	FALSE
4	GTEx	Cells Transformed fibroblasts	CD14	0.09	0.05	lasso	4	0.06	2.7e-05	-3.8	-5.2	2.1e-07	-0.05	0.16	0.73	FALSE
22	The Cancer Genome Atlas	Prostate Adenocarcinoma	EGR1	0.02	0.01	blup	41	0.02	1.9e-03	-4.6	-5.2	2.1e-07	-0.04	0.11	0.08	FALSE
17	YFS	Blood	TMCO6	0.01	0.00	blup	329	0.01	4.1e-03	-4.4	-5.2	2.4e-07	-0.03	0.13	0.79	FALSE
19	The Cancer Genome Atlas	Colon Adenocarcinoma	WDR55	0.09	0.08	enet	12	0.12	1.5e-07	-4.5	-5.2	2.4e-07	-0.05	0.02	0.93	FALSE
11	GTEx	Skin Sun Exposed Lower leg	WDR55	0.04	0.01	enet	10	0.01	2.8e-02	-4.4	-5.2	2.5e-07	-0.02	0.10	0.72	FALSE