[Hub]/) : Traits : Trunk fat percentage :

chr1:149,672,809-151,634,803

Best TWAS P=3.69e-23 · Best GWAS P=7.15e-33 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta RPRD2 0.08 -0.01 enet 19 0.00 4.2e-01 -4.1 8.3 1.6e-16 0.30 0.08 0.27 TRUE
2 GTEx Artery Tibial HIST2H2AA3 0.22 0.02 enet 20 0.12 1.8e-09 11.7 8.7 2.8e-18 0.70 0.00 1.00 TRUE
3 GTEx Artery Tibial RP11-196G18.22 0.25 0.05 lasso 5 0.07 1.8e-06 7.2 9.9 3.7e-23 0.78 0.01 0.99 TRUE
4 GTEx Artery Tibial RP11-196G18.24 0.31 0.08 enet 26 0.10 6.1e-08 11.7 8.3 7.9e-17 0.72 0.00 1.00 TRUE
5 GTEx Brain Cerebellum ECM1 0.34 0.21 lasso 6 0.19 3.2e-06 4.1 5.1 2.7e-07 0.17 0.39 0.39 TRUE
6 GTEx Brain Hypothalamus RP11-316M1.12 0.14 0.03 lasso 6 0.02 9.9e-02 -5.1 5.2 2.3e-07 0.09 0.08 0.28 FALSE
7 GTEx Breast Mammary Tissue (Male) RP11-54A4.2 0.07 0.01 enet 2 0.03 7.4e-02 6.0 6.1 1.2e-09 0.08 0.02 0.54 TRUE
8 GTEx Esophagus Gastroesophageal Junction ARNT 0.11 0.03 enet 18 0.02 8.8e-02 -3.5 -5.5 3.8e-08 -0.14 0.22 0.08 TRUE
9 GTEx Esophagus Muscularis BOLA1 0.07 0.00 lasso 4 0.00 2.5e-01 -5.1 5.8 5.5e-09 0.43 0.03 0.13 TRUE
10 GTEx Spleen RP11-54A4.2 0.29 0.10 lasso 9 0.04 3.8e-02 -5.2 5.3 1.1e-07 0.04 0.07 0.78 FALSE
11 GTEx Testis CTSK 0.07 0.01 enet 19 0.01 1.2e-01 -3.5 -5.4 5.4e-08 -0.03 0.06 0.85 TRUE
12 GTEx Thyroid MTMR11 0.09 0.05 enet 9 0.06 1.5e-05 -5.1 -5.4 5.9e-08 -0.40 0.26 0.41 FALSE
13 GTEx Thyroid ANP32E 0.08 0.00 enet 15 0.01 8.6e-02 -4.7 9.1 1.3e-19 0.37 0.04 0.12 TRUE
14 The Cancer Genome Atlas Breast Invasive Carcinoma SV2A 0.03 0.02 enet 3 0.02 8.0e-06 -3.3 5.6 2.8e-08 0.38 0.13 0.23 FALSE
15 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SV2A 0.05 0.02 blup 9 0.03 2.5e-04 -5.1 6.6 5.4e-11 0.48 0.03 0.07 FALSE
16 The Cancer Genome Atlas Lung Adenocarcinoma LASS2 0.03 0.01 blup 30 0.01 1.0e-02 -4.0 5.4 7.5e-08 0.10 0.00 0.03 FALSE
17 The Cancer Genome Atlas Prostate Adenocarcinoma SV2A 0.11 0.10 blup 9 0.11 3.8e-11 -3.3 5.3 1.1e-07 0.40 1.00 0.00 TRUE
18 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma RPRD2 0.14 0.13 enet 8 0.13 1.5e-04 4.7 5.4 8.2e-08 0.04 0.00 0.44 TRUE