[Hub]/) : Traits : Trunk fat percentage :

chr22:37,528,576-39,663,066

Best TWAS P=2.48e-22 · Best GWAS P=1.09e-21 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous BAIAP2L2 0.11 0.03 lasso 5 0.04 1.8e-04 7.5 -9.0 1.7e-19 -0.75 0.05 0.79 FALSE
2 GTEx Adipose Subcutaneous TMEM184B 0.08 0.08 lasso 4 0.07 1.0e-06 5.4 -6.6 4.7e-11 -0.57 0.84 0.11 FALSE
3 GTEx Artery Aorta C22orf23 0.10 0.01 enet 24 0.02 1.6e-02 2.5 6.2 5.7e-10 0.34 0.25 0.11 FALSE
4 GTEx Artery Aorta PLA2G6 0.10 0.02 enet 9 0.02 4.5e-02 5.2 8.3 1.0e-16 0.67 0.06 0.68 FALSE
5 GTEx Artery Aorta TMEM184B 0.17 0.07 enet 34 0.03 1.2e-02 8.6 -8.4 4.6e-17 -0.67 0.08 0.66 FALSE
6 GTEx Artery Aorta AL021977.1 0.13 0.00 enet 17 0.01 8.7e-02 8.8 -9.1 6.8e-20 -0.73 0.03 0.78 FALSE
7 GTEx Brain Cortex TMEM184B 0.29 0.12 lasso 7 0.09 1.6e-03 8.6 -8.9 5.3e-19 -0.90 0.01 0.90 FALSE
8 GTEx Cells EBV-transformed lymphocytes PLA2G6 0.28 0.17 enet 13 0.18 1.3e-06 -7.4 8.2 2.6e-16 0.70 0.23 0.64 FALSE
9 GTEx Cells Transformed fibroblasts ANKRD54 0.11 0.09 lasso 4 0.09 5.3e-07 -5.6 -5.7 9.7e-09 -0.20 0.81 0.02 TRUE
10 GTEx Cells Transformed fibroblasts PLA2G6 0.23 0.09 lasso 9 0.10 9.9e-08 7.4 8.3 7.3e-17 0.83 0.60 0.40 FALSE
11 GTEx Cells Transformed fibroblasts MAFF 0.08 0.08 lasso 3 0.06 2.2e-05 6.3 -5.3 1.4e-07 -0.71 0.35 0.24 FALSE
12 GTEx Cells Transformed fibroblasts TMEM184B 0.17 0.16 lasso 5 0.14 2.1e-10 5.4 -6.2 6.2e-10 -0.51 1.00 0.00 FALSE
13 GTEx Cells Transformed fibroblasts AL021977.1 0.08 0.08 enet 7 0.06 2.4e-05 5.4 -5.5 3.1e-08 -0.48 0.83 0.09 FALSE
14 GTEx Colon Sigmoid TMEM184B 0.20 0.03 lasso 4 -0.01 5.4e-01 5.4 -5.5 3.5e-08 -0.42 0.10 0.16 FALSE
15 GTEx Esophagus Gastroesophageal Junction PLA2G6 0.28 0.24 lasso 5 0.23 1.1e-08 -7.4 7.9 2.1e-15 0.65 0.75 0.13 FALSE
16 GTEx Esophagus Mucosa PLA2G6 0.22 0.02 lasso 6 0.04 1.9e-03 7.4 8.2 3.0e-16 0.80 0.05 0.94 FALSE
17 GTEx Esophagus Muscularis PLA2G6 0.12 0.00 enet 18 0.01 1.4e-01 7.4 7.3 3.7e-13 0.61 0.07 0.39 TRUE
18 GTEx Esophagus Muscularis TMEM184B 0.11 0.01 enet 10 0.06 2.7e-04 3.6 -6.4 1.6e-10 -0.60 0.26 0.21 TRUE
19 GTEx Muscle Skeletal ANKRD54 0.15 0.02 enet 21 0.04 1.1e-04 -5.6 -5.4 6.0e-08 -0.15 0.88 0.00 TRUE
20 GTEx Muscle Skeletal DMC1 0.13 0.01 enet 17 0.04 3.3e-05 7.5 6.4 1.4e-10 0.58 0.03 0.86 FALSE
21 GTEx Nerve Tibial PLA2G6 0.34 0.08 lasso 8 0.11 2.9e-08 -7.4 8.3 1.5e-16 0.74 0.94 0.06 FALSE
22 GTEx Nerve Tibial MAFF 0.14 0.06 lasso 3 0.05 1.2e-04 9.5 -9.4 4.3e-21 -0.99 0.00 0.99 FALSE
23 GTEx Nerve Tibial TMEM184B 0.16 0.12 lasso 7 0.14 3.6e-10 5.4 -5.7 1.2e-08 -0.44 0.99 0.00 FALSE
24 GTEx Nerve Tibial AL021977.1 0.16 0.05 lasso 3 0.07 9.3e-06 5.4 -6.8 1.3e-11 -0.60 0.55 0.42 FALSE
25 GTEx Skin Sun Exposed Lower leg ANKRD54 0.07 0.04 enet 17 0.04 1.6e-04 -5.6 -5.5 5.0e-08 -0.21 0.46 0.08 FALSE
26 GTEx Skin Sun Exposed Lower leg BAIAP2L2 0.09 0.09 lasso 4 0.09 5.5e-08 6.9 -7.4 1.7e-13 -0.77 0.23 0.77 FALSE
27 GTEx Thyroid PLA2G6 0.34 0.20 lasso 5 0.18 4.5e-14 -7.4 8.2 3.6e-16 0.68 1.00 0.00 FALSE
28 GTEx Thyroid TMEM184B 0.19 0.16 lasso 7 0.18 1.0e-13 5.4 -7.2 7.1e-13 -0.66 0.99 0.01 FALSE
29 GTEx Thyroid AL021977.1 0.20 0.11 lasso 6 0.12 2.7e-09 5.4 -7.5 6.3e-14 -0.65 0.96 0.04 FALSE
30 ROSMAP Brain Pre-frontal Cortex ANKRD54 0.03 0.00 blup 397 0.01 2.2e-02 1.9 -5.9 3.0e-09 -0.27 0.19 0.06 FALSE
31 YFS Blood TMEM184B 0.09 0.07 enet 38 0.09 7.8e-28 5.2 -6.0 2.0e-09 -0.52 1.00 0.00 FALSE
32 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ANKRD54 0.20 0.06 lasso 1 0.06 3.0e-07 -5.6 -5.6 2.1e-08 -0.17 0.00 1.00 TRUE
33 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PLA2G6 0.05 0.01 blup 76 0.01 7.7e-02 9.4 9.7 2.5e-22 0.85 0.01 0.82 TRUE
34 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma TMEM184B 0.03 0.03 lasso 2 0.03 7.7e-05 5.2 -5.4 7.2e-08 -0.44 0.24 0.18 FALSE
35 The Cancer Genome Atlas Brain Lower Grade Glioma BAIAP2L2 0.05 0.01 blup 52 0.03 3.7e-04 2.7 -5.9 3.4e-09 -0.44 0.08 0.25 FALSE
36 The Cancer Genome Atlas Thyroid Carcinoma PLA2G6 0.03 0.02 lasso 2 0.03 6.5e-04 8.3 8.3 8.3e-17 0.82 0.09 0.18 FALSE
37 The Cancer Genome Atlas Thyroid Carcinoma TMEM184B 0.03 0.04 lasso 2 0.04 1.6e-04 5.4 -5.4 6.2e-08 -0.44 0.15 0.21 FALSE