[Hub]/) : Traits : Trunk fat percentage : ← →

chr2:24,324,172-28,003,174

Best TWAS P=2.36e-38 · Best GWAS P=3.48e-30 conditioned to 0.909

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ADCY3	0.16	0.12	lasso	10	0.14	3.2e-17	11.077	-12.9	2.4e-38	-0.87	0.01	0.99	TRUE
2	CommonMind	Brain Pre-frontal Cortex	CENPO	0.07	0.03	bslmm	322	0.03	7.0e-05	7.521	-8.8	2.2e-18	-0.49	0.46	0.28	FALSE
3	GTEx	Adipose Subcutaneous	ADCY3	0.07	0.04	lasso	6	0.01	3.2e-02	10.447	9.9	4.2e-23	0.86	0.07	0.91	FALSE
4	GTEx	Adipose Subcutaneous	RP11-443B20.1	0.04	0.00	enet	10	0.00	1.2e-01	6.874	8.7	4.2e-18	0.81	0.04	0.90	FALSE
5	GTEx	Adrenal Gland	PTRHD1	0.32	0.28	lasso	3	0.26	8.3e-10	-4.896	5.3	9.0e-08	0.41	0.98	0.00	FALSE
6	GTEx	Artery Tibial	ADCY3	0.21	0.14	lasso	6	0.15	4.3e-12	10.065	11.3	7.7e-30	0.69	0.98	0.02	FALSE
7	GTEx	Artery Tibial	RP11-443B20.1	0.17	0.08	enet	40	0.09	8.2e-08	10.065	9.6	7.0e-22	0.59	0.44	0.52	FALSE
8	GTEx	Cells EBV-transformed lymphocytes	ADCY3	0.25	0.23	enet	10	0.12	9.2e-05	10.447	-8.2	2.0e-16	-0.84	0.02	0.97	FALSE
9	GTEx	Cells EBV-transformed lymphocytes	RP11-443B20.1	0.13	0.13	enet	9	0.05	9.2e-03	10.447	-10.5	5.3e-26	-0.93	0.01	0.96	FALSE
10	GTEx	Esophagus Gastroesophageal Junction	KHK	0.16	0.11	enet	16	0.09	3.6e-04	-5.095	-5.5	4.8e-08	-0.01	0.44	0.47	FALSE
11	GTEx	Nerve Tibial	ADCY3	0.09	0.05	enet	6	0.03	2.2e-03	10.065	-11.9	7.6e-33	-0.91	0.01	0.99	FALSE
12	GTEx	Nerve Tibial	RP11-443B20.1	0.07	0.03	enet	6	0.02	1.1e-02	10.065	-11.7	1.6e-31	-0.81	0.03	0.96	FALSE
13	GTEx	Prostate	EPT1	0.21	-0.01	enet	23	0.00	3.2e-01	-2.464	-5.5	3.6e-08	0.01	0.08	0.07	TRUE
14	GTEx	Skin Sun Exposed Lower leg	MAPRE3	0.12	0.15	lasso	7	0.14	9.5e-12	-4.852	-5.2	1.8e-07	0.00	0.88	0.12	FALSE
15	GTEx	Whole Blood	DNAJC27	0.08	0.10	lasso	1	0.10	2.2e-09	10.390	10.4	2.8e-25	0.80	0.87	0.13	FALSE
16	GTEx	Whole Blood	ADCY3	0.23	0.24	enet	24	0.27	5.5e-25	10.604	11.7	1.2e-31	0.86	0.91	0.09	FALSE
17	GTEx	Whole Blood	RP11-443B20.1	0.21	0.17	enet	32	0.20	1.8e-18	10.390	12.1	1.8e-33	0.86	0.74	0.26	FALSE
18	METSIM	Adipose	EFR3B	0.04	0.00	bslmm	357	0.00	9.7e-02	0.096	-5.7	1.4e-08	-0.37	0.06	0.08	FALSE
19	ROSMAP	Brain Pre-frontal Cortex	ADCY3	0.17	0.26	enet	32	0.26	6.8e-33	10.604	-11.6	3.5e-31	-0.89	0.74	0.26	FALSE
20	ROSMAP	Brain Pre-frontal Cortex	KCNK3	0.24	0.15	lasso	3	0.15	6.5e-19	6.273	-6.3	3.4e-10	0.03	0.00	1.00	TRUE
21	ROSMAP	Brain Pre-frontal Cortex	SLC35F6	0.05	0.04	enet	11	0.04	8.0e-06	-5.535	5.3	1.0e-07	-0.01	0.16	0.84	FALSE
22	YFS	Blood	ADCY3	0.07	0.02	bslmm	343	0.04	7.3e-14	11.349	-6.4	1.3e-10	-0.61	0.00	1.00	FALSE
23	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	ABHD1	0.18	0.02	enet	5	0.06	7.1e-04	-3.228	-5.3	1.3e-07	-0.07	0.00	0.50	TRUE
24	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	POMC	0.06	0.00	enet	12	0.03	9.3e-05	-1.082	-5.5	3.9e-08	-0.27	0.01	0.41	FALSE
25	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	EFR3B	0.03	0.05	lasso	1	0.04	1.9e-05	-8.102	-8.1	5.4e-16	-0.67	0.56	0.06	FALSE
26	The Cancer Genome Atlas	Brain Lower Grade Glioma	ADCY3	0.03	0.02	blup	81	0.02	7.1e-04	6.485	-9.9	4.0e-23	-0.87	0.04	0.93	FALSE
27	The Cancer Genome Atlas	Lung Adenocarcinoma	DNAJC27	0.05	0.01	blup	46	0.04	3.2e-05	2.445	-5.4	7.3e-08	-0.55	0.35	0.60	FALSE
28	The Cancer Genome Atlas	Lung Adenocarcinoma	POMC	0.14	0.04	enet	7	0.08	5.3e-10	-1.082	-5.6	2.0e-08	-0.22	0.38	0.62	FALSE
29	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	POMC	0.22	0.05	blup	37	0.03	2.1e-02	-1.556	-5.4	8.1e-08	-0.12	0.01	0.29	FALSE
30	The Cancer Genome Atlas	Prostate Adenocarcinoma	POMC	0.11	0.08	enet	7	0.09	1.6e-09	-1.082	-5.3	9.3e-08	-0.24	0.92	0.06	FALSE