Hub : Genes

EPT1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Colon Sigmoid 0.1070 0.0490 6.2e-03 -0.003 NA -0.005 NA -0.008 4.2e-01 NA 5.1e-01 NA 7.8e-01
2 GTEx Muscle Skeletal 0.0981 0.0339 8.5e-04 0.031 NA 0.035 NA 0.041 4.2e-04 NA 2.2e-04 NA 6.1e-05
3 GTEx Pituitary 0.3220 0.0970 4.5e-04 0.012 NA 0.054 NA 0.034 1.6e-01 NA 1.8e-02 NA 4.9e-02
4 GTEx Prostate 0.2090 0.0860 4.2e-03 -0.010 NA 0.000 NA -0.011 7.1e-01 NA 3.2e-01 NA 7.5e-01
5 GTEx Skin Sun Exposed Lower leg 0.0830 0.0360 4.5e-03 0.036 NA 0.035 NA 0.029 5.8e-04 NA 6.9e-04 NA 1.9e-03
6 METSIM Adipose 0.0478 0.0249 4.4e-03 0.000 0.008 0.016 0.012 0.001 3.9e-01 0.02100 1.6e-03 0.0049 2.2e-01
7 ROSMAP Brain Pre-frontal Cortex 0.0728 0.0248 3.9e-05 0.056 0.024 0.048 0.009 -0.001 8.9e-08 0.00040 6.9e-07 0.0240 5.9e-01
8 TCGA Kidney Renal Clear Cell Carcinoma 0.0329 0.0189 1.9e-03 0.006 0.014 0.019 NA 0.016 7.0e-02 0.00820 3.0e-03 NA 5.2e-03
9 TCGA Testicular Germ Cell Tumors 0.1680 0.0720 4.4e-05 0.156 0.102 0.118 NA 0.154 3.7e-06 0.00019 5.9e-05 NA 4.2e-06

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bipolar Disorder (2018) 0.7 1.1 4.3 0.3 0.5 0.4 -0.3 2.1 1.5 1.5 0.5 0.3
Bipolar Disorder or Schizophrenia 0.9 2.2 4.6 -1.3 0.6 -0.2 -2.1 2.1 2.1 1.6 1.3 0.5
Depressed Affect (Nagel 2018) 0.1 0.2 0.9 0.4 -0.0 -1.0 0.2 -0.1 -0.6 0.6 -0.3 -0.0
Depression (Nagel 2018) 0.2 0.3 0.9 0.9 -0.3 0.6 0.3 0.0 -0.8 0.5 0.2 -0.2
Intelligence (Savage-Jansen 2018) 0.2 0.6 1.9 0.9 -0.2 -1.4 1.1 -0.8 0.2 0.7 0.4 0.0
Neuroticism (Nagel 2018) 0.4 1.0 2.0 -0.6 -1.4 -0.4 -1.0 0.9 -1.1 1.3 -0.4 -1.3
Schizophrenia (2018) 0.9 1.8 6.2 -1.9 0.4 -0.6 -2.5 1.1 1.6 0.7 1.2 0.4
Schizophrenia vs Biploar Disorder 0.6 0.8 2.0 -1.3 0.4 0.8 -1.4 0.2 0.3 -1.1 0.8 0.4
Worry (Nagel 2018) 1.5 3.3 5.9 -2.2 -2.4 0.3 -2.3 1.2 -1.4 2.2 -0.3 -2.3
Alzheimer’s Disease (in mother) 1.2 1.5 4.0 0.5 -2.0 1.7 0.5 0.3 -1.0 1.1 -0.7 -1.7
Alzheimer’s Disease (in father) 0.9 1.0 3.6 -0.4 -1.5 1.9 -0.2 -0.3 -0.7 1.3 -0.2 -0.9
Alzheimer’s Disease (including proxy) 1.3 1.9 5.8 -0.3 -2.1 2.4 0.1 0.2 -0.7 1.7 -0.4 -1.6
Crohns Disease (2017) 0.1 0.2 0.7 -0.1 -0.3 -0.3 -0.4 0.1 0.4 0.5 0.8 0.0
Irritable Bowel Disease (IBD) 0.1 0.1 0.4 0.0 -0.4 -0.7 -0.3 -0.6 -0.2 0.4 -0.1 0.1
Ulcerative Colitis (UC) 0.2 0.3 1.3 0.2 -0.3 -0.8 -0.0 -1.1 -0.5 0.0 -0.6 0.2
Major Depression (MDD) 1.2 1.5 3.8 -1.9 0.9 -1.5 -0.9 0.4 1.8 -0.7 0.9 1.0
Reaction Time 0.7 1.4 4.7 0.4 -0.9 2.2 0.4 1.1 -1.6 0.9 -0.8 -1.4
Verbal and Numeric Reasoning (VNR) 0.2 0.5 1.5 0.7 -0.3 -0.5 0.6 0.7 0.5 1.2 1.0 -0.4
Breast Cancer 0.7 1.6 4.2 2.0 -0.0 -2.0 -1.2 -0.8 -0.7 0.2 -1.8 0.0
Ovarian Cancer 0.3 0.4 1.4 0.0 -0.1 0.1 0.0 -0.7 -1.2 -0.5 1.0 -0.1
Prostate Cancer 0.4 0.5 1.3 -0.3 -0.4 -0.2 -1.1 1.1 -0.4 0.6 -0.9 -0.7
Age at First Birth 0.4 0.6 1.3 -1.0 0.9 -1.1 -0.8 0.7 0.5 -0.8 0.4 0.6
Bipolar Disorder (2011) 1.1 1.0 3.0 0.5 0.9 0.8 0.0 1.7 1.3 1.0 1.2 0.7
Body Mass Index (BMI) (2010) 0.3 0.4 2.1 1.4 -0.1 0.4 -0.7 -0.1 0.1 0.5 -0.7 0.0
Coronary Artery Disease (CAD) 1.4 1.6 3.2 -1.7 1.3 1.6 -0.2 0.5 1.8 -0.6 1.6 1.1
Crohns Disease (2012) 0.4 0.7 2.3 -0.6 0.5 0.2 -0.1 0.8 1.4 0.4 1.5 0.5
Mean Putamen Volume 0.6 0.7 1.5 0.5 1.1 -0.6 0.4 -1.2 -0.0 -1.2 0.3 1.2
Fasting Glucose 1.7 2.1 5.0 -0.9 -2.2 0.7 0.7 -0.2 -1.5 1.6 -1.6 -2.2
HbA1C 0.8 0.9 3.8 -1.9 -0.4 -1.0 -1.3 -1.2 -0.3 -0.1 0.1 0.2
HDL Cholesterol 1.5 2.5 6.0 0.9 -2.1 1.9 0.7 1.6 -0.0 1.9 -1.2 -2.4
LDL Cholesterol 1.5 2.4 5.1 1.3 1.9 0.6 1.8 -1.2 1.0 -1.8 1.5 2.3
Lupus 0.2 0.2 0.7 0.6 -0.4 -0.7 0.9 -0.4 0.0 -0.3 -0.3 -0.3
Neuroticism (2016) 0.7 0.9 2.6 -1.6 1.4 0.9 0.1 0.1 -0.2 -0.8 1.2 1.0
Primary Biliary Cirrhosis 0.6 0.9 3.1 -1.1 -0.9 0.0 -1.8 0.1 -0.2 1.0 -0.9 -1.0
Rheumatoid Arthritis 0.9 1.2 3.8 0.5 -1.5 -0.6 1.2 -1.1 -0.9 -0.1 -1.9 -0.9
Schizophrenia (2014) 0.7 1.6 5.4 -2.3 0.8 -0.3 -2.0 0.6 1.4 0.2 1.2 0.9
Triglycerides 0.3 0.4 2.0 0.4 -0.3 -1.4 -0.4 0.1 0.5 0.6 -0.9 0.1
Type 2 Diabetes (T2D) (2012) 2.2 2.5 7.0 0.2 2.6 -0.9 -0.0 0.1 2.5 -0.9 1.0 2.6
Ulcerative Colitis 0.2 0.3 0.8 0.3 -0.0 -0.8 -0.9 -0.7 0.1 0.2 -0.4 0.4
Blood Eosinophil Count 0.2 1.8 5.2 -0.5 -0.1 -2.3 -1.6 -1.6 -1.1 -0.8 -1.9 0.3
Blood Platelet Count 0.4 4.5 14.3 -3.8 1.4 -3.5 -2.5 -0.6 1.6 -0.7 0.5 1.5
Blood Red Count 0.4 3.6 12.2 -3.5 2.3 -1.5 -1.6 -1.6 1.2 -0.6 0.2 2.3
Blood White Count 0.5 4.0 12.9 -2.3 1.5 -3.6 -1.5 -2.1 0.2 -2.4 -0.1 1.8
Heel T-Score 0.3 2.0 11.3 -1.8 0.8 -0.5 -3.4 0.9 -0.2 -0.3 1.2 0.0
BMI 0.3 1.9 9.0 -0.2 2.0 0.8 -3.0 1.1 0.8 0.0 0.5 1.1
Height 0.2 3.6 11.9 3.1 -1.0 0.9 1.0 -0.6 -3.5 -0.8 -2.4 -1.1
Waist Hip Ratio (WHR) 0.6 2.6 9.7 -0.6 -1.9 -0.5 -3.1 -1.3 -2.1 0.6 -0.2 -1.7
Systolic Blood Pressure 0.3 1.4 5.7 -2.4 0.3 -1.6 -0.7 -0.9 -1.1 -1.0 -0.6 0.6
Smoking Status 0.2 0.5 2.8 1.7 -0.3 -0.0 0.4 0.7 0.6 -0.0 0.3 -0.6
Allergy or Eczema 0.3 0.7 2.3 -0.4 1.3 -0.3 -0.8 0.8 0.8 -1.5 -0.1 0.5
Cardiovascular Disease 0.2 0.5 2.1 0.0 0.7 0.2 -1.4 0.7 -0.8 0.5 0.3 0.7
Hypothyroidism (self reported) 0.4 1.0 3.6 0.6 0.4 1.9 1.6 0.8 -0.5 -0.6 0.7 -0.3
Respiratory disease 1.3 2.9 5.8 -1.9 1.8 0.4 -2.1 2.4 2.0 -1.0 1.7 1.1
Type 2 Diabetes (T2D) (2018) 0.6 1.0 3.3 -1.8 1.1 1.3 -0.6 0.6 -0.6 -0.5 1.1 0.7
Lung FEV1/FVC ratio 0.3 1.8 4.2 0.9 1.7 1.6 0.6 2.0 1.3 1.3 0.9 0.9
Lung FVC 0.6 2.8 9.0 -0.5 -0.0 -2.4 1.7 -3.0 -0.1 -2.4 -1.4 0.5
Neuroticism 0.2 0.6 2.6 -0.5 -0.7 -0.3 0.4 -1.0 -1.6 -0.6 -0.1 -0.3
Chronotype (morning person) 0.4 1.0 4.8 -0.2 0.1 0.6 2.2 -0.4 -1.6 0.5 -1.1 0.1
Hair Pigment 0.1 2.1 8.3 0.9 0.5 -1.1 -0.1 -2.5 -1.3 -2.9 -0.4 0.3
Tanning 0.2 2.5 10.8 -0.6 1.3 1.8 -0.2 0.8 1.9 -0.4 3.3 1.4
Hand grip strength (left) 1.5 4.0 7.7 1.5 -2.6 1.7 1.4 0.6 -0.5 2.8 -2.7 -2.4
Number of treatments/medications taken 1.0 1.7 7.3 -0.6 1.0 -0.8 -1.1 -1.3 -2.7 -1.2 0.9 1.1
Average weekly spirits intake 0.3 0.4 0.8 -0.3 0.8 0.1 -0.8 0.9 0.9 -0.7 -0.0 0.2
Sensitivity / hurt feelings 0.4 0.8 1.3 -1.1 -0.8 -1.2 -1.0 -0.2 -1.1 -0.4 -0.8 -0.7
Frequency of depressed mood in last 2 weeks 0.3 0.5 2.2 1.0 0.1 0.8 0.2 0.5 -1.5 0.4 -0.2 -0.3
Hearing difficulty/problems: Yes 0.3 0.5 1.5 0.6 0.9 -1.2 -0.6 -0.4 -0.3 -0.4 -0.5 0.9
Relative age of first facial hair 0.5 0.9 2.6 1.4 1.0 0.1 1.6 -0.5 0.7 -0.6 0.5 1.2
Other serious medical condition/disability diagnosed by doctor 2.1 2.7 5.5 -0.9 1.8 -1.3 0.7 -2.1 -1.1 -2.4 1.3 2.2
Ever used hormone-replacement therapy (HRT) 2.1 2.7 4.9 2.1 -1.4 1.9 1.0 1.4 -2.2 1.5 -0.4 -2.0
Ever had hysterectomy (womb removed) 0.5 0.6 3.0 -0.3 0.4 -0.5 -1.7 -0.6 0.9 0.1 0.5 0.6
Systolic blood pressure, automated reading 1.0 2.9 6.1 -2.4 1.7 -1.9 -1.8 -1.0 0.6 -2.5 0.4 1.7
Eye problems/disorders: Diabetes related eye disease 0.8 0.9 2.3 -0.0 1.5 0.7 0.2 1.5 0.6 -0.9 0.7 1.0
Angina 1.0 1.3 3.0 -0.6 1.7 -0.8 -1.1 0.7 1.2 -1.2 0.6 1.6
Medication for hormone replacement therapy 1.3 1.4 3.3 -1.8 1.4 0.8 -1.2 0.6 0.5 -0.4 1.8 1.2
Vitamin and mineral supplements 0.7 0.9 2.4 -0.7 1.2 -0.0 -0.6 -0.5 0.8 -0.4 1.5 1.5
Supplements: Zinc 0.9 1.0 2.7 1.3 -0.6 0.5 1.5 -0.8 -0.7 0.2 -1.6 -0.7
Medication: Co-codamol 1.6 1.8 7.6 -0.9 1.0 1.6 -0.9 1.6 0.8 0.6 2.8 0.5
Medication: Metformin 0.5 0.7 1.7 -1.2 0.8 -0.3 -1.3 0.8 -0.2 -0.7 0.7 0.4
Diabetes (father) 2.9 3.5 10.8 -1.0 2.4 -2.2 -0.9 -1.5 -0.3 -3.3 -0.6 2.5
Diabetes (mother) 0.8 1.1 2.4 1.4 0.9 1.4 1.2 -0.3 -0.2 -1.6 -0.2 0.9
Severe depression (siblings) 1.0 1.1 1.7 -1.2 1.2 -0.1 -0.6 1.2 1.1 -1.0 1.3 1.0
Pack years adult smoking proportion 0.8 1.2 2.6 0.2 -1.5 0.5 -1.5 -0.3 -0.9 1.6 -0.1 -1.6
Impedance of leg (right) 0.4 1.9 4.8 -0.9 -2.2 -2.1 0.3 -0.9 -0.6 0.8 -1.6 -1.5
Leg fat-free mass (left) 0.3 1.7 5.8 -0.0 2.4 1.0 -2.0 0.0 -0.9 -1.0 0.4 1.6
Trunk fat percentage 1.5 5.9 30.4 -2.3 2.7 -1.5 -5.5 0.5 1.5 -1.1 1.3 1.7
Hand grip strength (right) 0.8 2.0 5.7 0.7 -1.6 1.0 1.7 -0.8 -1.6 1.0 -2.4 -1.3
Townsend deprivation index at recruitment 0.6 0.8 1.9 0.6 1.3 1.4 0.9 -0.5 -0.6 -0.9 -0.2 1.1
Current tobacco smoking 0.6 1.0 2.3 1.5 -1.4 0.4 -0.1 0.2 -1.3 0.6 -0.4 -1.4
Average weekly fortified wine intake 0.4 0.4 2.4 0.4 -0.5 0.2 -0.0 0.2 1.6 0.5 -0.6 -0.7
Maternal smoking around birth 0.4 0.5 2.5 -0.5 0.5 -0.8 -1.6 -0.5 0.3 0.5 0.5 0.6
Fed-up feelings 0.1 0.2 0.5 0.6 -0.3 0.0 0.7 0.1 -0.6 0.7 -0.1 -0.4
Frequency of unenthusiasm / disinterest in last 2 weeks 0.4 0.6 2.6 -0.0 -0.2 0.6 -0.1 0.5 -1.6 1.1 0.5 -0.5
Relative age voice broke 0.4 0.6 3.8 1.9 -0.5 0.1 0.9 -0.7 0.3 0.2 0.4 -0.2
Taking other prescription medications 0.5 0.8 2.5 0.0 0.7 0.0 0.0 -1.1 -1.6 -0.9 1.2 0.8
Age when periods started (menarche) 1.2 2.8 10.2 1.8 -1.7 3.2 1.5 1.4 -0.5 1.1 -0.1 -1.7
Bilateral oophorectomy (both ovaries removed) 0.5 0.6 1.7 0.4 1.3 0.2 0.5 -0.0 0.6 -0.9 0.8 1.1
Heel bone mineral density (BMD) T-score, automated (left) 0.5 1.2 2.5 1.4 -0.7 1.6 1.5 0.8 -0.2 1.1 0.5 -1.2
Tinnitus: Yes, but not now, but have in the past 0.3 0.3 1.3 1.1 -0.1 1.1 0.3 -0.2 -0.5 -0.1 0.4 -0.1
Qualifications: CSEs or equivalent 1.4 1.8 6.2 -2.5 1.9 0.5 -0.3 -0.4 -0.5 -0.5 1.4 1.9
Serious illness, injury or assault to yourself 1.1 1.4 2.9 -1.3 0.5 -1.2 -0.6 -1.5 -1.7 -1.5 0.3 1.1
High blood pressure 0.8 2.4 8.3 -1.7 1.5 -1.2 -2.9 -0.1 -0.1 -1.2 1.4 1.6
Hayfever, allergic rhinitis or eczema 0.5 1.1 4.4 -0.2 1.7 -0.0 -0.3 0.1 0.6 -2.1 0.7 1.2
Multivitamins +/- minerals 0.3 0.3 1.2 -0.7 0.0 -0.4 -0.0 0.2 -1.1 -0.5 -0.9 -0.5
Stomach or abdominal pain in last month 0.5 0.6 2.5 -0.4 -1.1 -0.2 0.5 -0.4 -1.6 0.5 -0.4 -0.8
Supplements: Glucosamine 2.2 2.9 8.1 0.9 -2.3 -1.0 -0.4 -1.0 -1.8 1.2 -2.9 -2.1
Diverticular disease/diverticulitis (self-reported) 0.5 0.6 2.0 -0.3 0.4 1.1 1.4 0.4 -0.5 -0.8 0.9 -0.1
Medication: Atenolol 0.2 0.2 0.7 -0.1 0.8 -0.3 -0.2 0.3 -0.5 -0.3 0.5 0.5
Medication: Levothyroxine sodium 0.2 0.4 2.2 -0.1 -0.3 0.6 0.3 0.4 -1.5 -0.3 -0.1 -0.8
Sitting height 0.2 1.6 5.3 1.6 -0.9 1.5 0.4 0.0 -2.3 0.7 -1.4 -0.9
Chronic bronchitis/emphysema (father) 0.4 0.5 2.2 -0.4 0.8 -0.3 -1.5 0.6 0.9 -0.3 -0.3 0.5
High blood pressure (mother) 0.4 0.6 1.4 -0.8 -0.0 -1.0 -1.0 -1.2 -0.8 0.2 0.5 0.3
Body mass index (BMI) 1.2 5.0 15.0 -2.1 3.5 -0.3 -3.9 0.7 1.1 -1.2 1.9 2.4
Impedance of leg (left) 0.5 2.6 8.1 -0.3 -2.8 -2.0 0.3 -0.6 -0.4 1.6 -2.0 -2.1
Leg predicted mass (left) 0.3 1.7 5.6 0.0 2.4 1.0 -2.1 0.0 -0.9 -1.0 0.3 1.6
Trunk fat mass 1.1 4.8 26.1 -1.9 2.7 -1.0 -5.1 0.5 0.9 -0.9 0.9 1.6
Waist circumference 1.3 4.7 25.8 -1.9 2.6 -0.6 -5.1 0.6 0.4 -0.9 1.4 1.6
Number of incorrect matches in round 0.5 0.8 3.2 -0.4 0.1 -0.4 -1.0 -0.5 -1.6 -1.8 0.2 0.4
Past tobacco smoking 0.2 0.3 1.2 -0.5 -0.1 1.1 0.0 -0.6 -0.8 0.2 0.4 0.2
Alcohol usually taken with meals 0.5 0.9 2.1 0.8 0.3 0.4 1.3 -1.2 1.5 -0.3 0.8 0.9
Nervous feelings 1.8 3.3 9.1 -1.3 -3.0 -0.0 -1.3 0.4 -2.5 1.5 -1.1 -2.7
Frequency of tenseness / restlessness in last 2 weeks 0.5 0.8 2.3 1.1 -0.4 1.5 0.9 0.9 0.3 1.1 0.5 -0.7
Hearing difficulty/problems with background noise 0.6 0.9 3.1 -0.4 0.9 -1.8 -0.0 -0.5 -0.7 -1.0 -1.3 0.8
Hair/balding pattern: Pattern 2 2.1 2.6 6.9 -0.7 2.6 -0.7 0.0 0.3 2.2 -1.2 1.9 2.5
Had menopause 0.6 0.8 1.7 0.7 -0.3 1.3 -0.8 1.2 -0.7 1.1 0.6 -0.7
Had other major operations 0.3 0.4 1.5 0.8 0.4 -0.6 0.3 -0.1 1.2 -0.6 0.7 0.6
Forced vital capacity (FVC) 0.5 1.9 6.5 1.0 -0.7 -1.1 1.3 -1.8 -1.4 -0.7 -2.5 -0.0
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.6 1.6 1.3 -0.5 1.1 0.8 -0.5 -0.6 0.3 0.7 -0.6
Ever unenthusiastic/disinterested for a whole week 0.4 0.5 1.5 0.6 -0.3 1.2 0.3 0.6 -1.0 0.4 0.1 -0.8
Qualifications: None of the above 0.7 1.5 3.4 -1.0 1.4 0.4 -1.3 1.7 1.8 -0.2 1.3 0.7
Financial difficulties in last 2 years 0.4 0.6 1.6 0.2 0.9 1.3 -0.7 1.0 -0.3 0.9 -0.3 0.3
Mouth/teeth dental problems 0.5 0.7 2.2 -0.6 -1.0 -0.8 -1.5 0.5 -0.1 1.2 -0.1 -0.7
Heart attack 0.8 1.0 3.1 0.3 1.4 -0.3 0.5 -0.5 0.2 -1.5 1.8 1.2
Allergy 1.3 2.9 7.1 0.8 -2.7 0.1 0.4 -0.3 -1.8 2.5 -2.0 -2.2
Pain all over the body in last month 0.9 1.0 4.0 0.4 -0.3 -1.2 -2.0 -1.3 -1.0 0.3 -0.6 -0.0
Diabetes (self-reported) 1.4 2.2 5.1 -2.3 2.0 0.3 -1.0 0.6 -0.2 -1.9 1.7 1.6
Hayfever/allergic rhinitis (self-reported) 0.1 0.1 0.4 -0.3 -0.0 0.0 -0.6 0.2 -0.3 -0.6 0.4 -0.3
Medication: Ramipril 0.9 1.1 3.4 -0.1 1.8 -0.3 0.5 -0.5 -0.4 -1.8 0.4 1.6
Medication: Simvastatin 0.7 1.0 2.0 -0.5 1.3 -0.7 -1.4 -0.5 -0.8 -1.4 0.7 1.1
Fluid intelligence score 0.4 0.8 3.1 1.0 -0.8 -0.4 1.0 0.4 0.7 1.8 0.5 -0.9
Illnesses of siblings 0.6 0.8 1.5 1.2 -1.2 0.6 0.7 -0.7 -1.1 0.9 -0.6 -0.7
Neuroticism score 0.3 0.5 2.0 -1.4 -0.7 -0.2 -0.2 0.0 -1.4 -0.0 -0.0 -0.7
Weight 0.6 3.1 13.2 -0.8 2.9 0.2 -3.6 0.5 -0.1 -0.9 0.9 1.9
Impedance of arm (right) 0.2 1.2 5.4 -0.7 -0.2 -2.3 -1.2 0.0 1.6 -0.8 0.2 0.2
Arm fat percentage (right) 1.9 7.6 27.8 -3.2 3.5 -1.3 -5.3 0.6 1.9 -1.6 1.9 2.5
Trunk fat-free mass 0.2 1.0 2.8 0.6 1.4 1.6 0.1 -0.1 -1.7 -0.1 -0.6 0.9
Hip circumference 1.1 4.6 13.7 -1.3 3.5 -0.2 -3.7 1.7 1.7 -1.0 1.4 2.3
Time employed in main current job 0.5 0.6 2.3 0.0 0.3 0.0 -0.5 0.7 -0.4 -1.5 1.4 0.1
Alcohol intake versus 10 years previously 0.8 1.2 2.2 1.1 -1.1 1.5 0.5 -0.2 -1.4 1.3 -0.4 -1.4
Father’s age at death 1.1 1.5 3.8 0.7 -1.9 1.0 -1.1 0.7 -0.4 1.4 -1.0 -2.0
Worrier / anxious feelings 0.3 0.5 1.8 -1.1 -0.8 0.5 -0.2 -0.2 -1.3 0.1 0.3 -0.7
Frequency of tiredness / lethargy in last 2 weeks 0.5 0.8 2.8 -1.7 1.2 -0.0 -1.1 0.8 0.0 -0.5 0.5 0.7
Falls in the last year 0.8 1.1 3.2 -0.6 1.0 -1.8 -1.0 0.5 0.9 -1.2 1.0 0.9
Hair/balding pattern: Pattern 3 2.2 3.3 8.1 2.0 -2.4 0.8 -0.7 0.9 -1.0 1.8 -2.4 -2.8
Number of live births 0.6 0.9 1.7 -1.2 1.0 0.3 -0.8 0.2 1.3 -0.0 1.3 1.3
Forced expiratory volume in 1-second (FEV1) 0.4 1.3 4.2 0.8 -0.0 -0.5 1.8 -1.4 -1.1 -0.5 -2.0 0.6
Pulse rate 0.6 1.0 3.2 -0.0 -0.4 0.4 -1.1 1.8 1.2 1.4 0.2 -0.7
Happiness 1.1 1.3 3.2 0.2 -1.3 0.4 0.5 0.5 -1.8 1.2 -1.6 -1.6
Noisy workplace 0.7 0.8 3.4 -0.2 1.1 -1.9 -0.0 -0.0 0.0 -1.4 -0.5 0.6
Qualifications: A levels/AS levels or equivalent 0.5 1.1 3.5 0.9 -0.3 -1.1 1.9 -1.6 0.0 -1.0 -0.7 0.1
Serious illness, injury or assault of a close relative in last 2 years 0.5 0.6 2.0 -0.8 -0.4 1.0 0.4 0.6 -0.8 1.4 -0.1 -0.5
Mouth/teeth dental problems: Dentures 0.6 1.0 5.1 0.6 0.7 2.2 1.4 0.2 -0.9 -0.5 -0.2 0.2
Asthma 1.2 2.4 5.7 -2.0 1.3 -0.1 -2.3 2.4 1.8 -0.2 1.0 0.6
Medication: Ibuprofen (e.g. Nurofen) 0.6 0.8 3.0 -1.1 0.4 -0.4 -1.7 0.3 -1.4 -0.8 -0.2 0.1
Medication: Cholesterol lowering 1.4 2.2 7.1 0.2 2.2 -1.5 0.6 -1.0 0.3 -2.7 0.6 2.1
Depression (self-reported) 0.8 1.0 3.3 -1.5 -1.0 -0.4 1.0 -0.1 -1.8 0.4 -0.8 -0.8
Medication: Lansoprazole 0.6 0.7 2.2 0.7 0.8 0.1 0.0 -1.5 -0.7 -1.1 0.9 0.7
Prospective memory result 0.3 0.4 1.3 -0.2 0.6 -0.6 -0.2 -0.9 -0.5 -1.2 -0.1 0.7
Lung cancer (father) 0.1 0.1 0.8 0.1 -0.1 0.9 0.0 -0.3 -0.1 -0.1 0.4 -0.2
Illnesses of mother 0.2 0.3 1.3 0.3 -0.2 0.1 0.7 0.3 1.2 -0.0 -0.6 -0.3
Forced expiratory volume in 1-second (FEV1), Best measure 0.4 1.2 3.5 0.5 0.0 -0.7 1.6 -1.4 -1.3 -0.2 -1.9 0.7
Pulse wave Arterial Stiffness index 1.2 1.4 3.3 0.2 -0.7 -1.4 -1.8 1.2 0.5 0.8 -1.8 -1.1
Impedance of arm (left) 0.2 0.9 4.1 -0.3 -1.0 -2.0 -0.8 0.1 1.4 -0.5 -0.3 -0.4
Arm fat mass (right) 1.3 5.2 23.2 -2.3 3.1 -0.6 -4.8 0.7 1.0 -1.0 1.3 2.0
Trunk predicted mass 0.2 1.0 2.8 0.8 1.3 1.7 0.2 -0.0 -1.7 0.0 -0.7 0.8
Standing height 0.2 2.3 6.3 2.4 -1.1 1.1 0.1 -0.3 -2.5 0.7 -2.1 -1.0
Length of working week for main job 1.8 2.0 5.0 1.4 -1.4 2.2 0.8 1.3 -0.9 1.2 -1.1 -1.8
Exposure to tobacco smoke at home 0.4 0.5 3.1 0.1 0.3 0.1 -0.3 1.8 -0.8 -0.1 -0.6 -0.4
Breastfed as a baby 1.2 1.4 3.4 0.5 1.3 -0.2 0.9 -1.2 -0.7 -1.6 1.8 1.6
Tense / ‘highly strung’ 1.1 1.8 4.8 -2.2 -1.4 0.9 -1.3 1.4 -0.9 0.8 -0.0 -1.8
Seen doctor (GP) for nerves, anxiety, tension or depression 0.3 0.4 1.4 -0.1 -0.4 -1.2 0.7 -0.3 -0.7 -0.1 -1.1 -0.3
Hair/balding pattern: Pattern 4 0.3 0.7 1.7 -1.1 -0.1 -1.3 -0.2 -1.1 -0.5 -1.3 -0.5 0.3
Birth weight of first child 0.3 0.5 1.6 -0.2 0.1 -1.3 0.1 -0.1 -1.1 0.9 -0.7 -0.2
Peak expiratory flow (PEF) 0.4 1.0 3.3 0.8 0.9 -0.6 1.8 -1.0 0.4 -1.0 -0.8 1.1
Pulse wave reflection index 0.9 1.1 2.9 0.7 -1.2 -0.7 -0.3 -0.3 -1.7 1.0 -1.4 -1.2
Ever highly irritable/argumentative for 2 days 0.6 0.7 1.7 0.8 -0.6 0.3 0.4 1.1 0.8 1.3 -0.7 -1.1
Loud music exposure frequency 0.8 0.9 2.1 -1.4 1.4 -0.7 -1.1 0.1 0.3 -1.1 -0.0 1.0
Qualifications: O levels/GCSEs or equivalent 0.5 0.7 2.4 0.4 -0.2 -1.1 0.7 -1.5 -0.7 -0.6 -1.2 0.1
Mouth/teeth dental problems: Bleeding gums 0.4 0.5 2.8 1.7 -0.6 -0.3 0.6 -0.4 0.0 0.1 -0.7 -0.5
Blood clot in the leg (DVT) 1.1 1.4 3.2 0.7 1.1 0.8 1.3 -1.4 -0.8 -1.8 0.7 1.5
Medication: Paracetamol 0.8 1.3 2.6 -1.6 1.2 -0.5 -0.9 -1.0 -0.7 -1.3 1.0 1.4
Headache pain in last month 0.4 0.7 2.9 -0.6 0.3 1.7 0.1 1.5 -0.6 0.2 0.7 -0.1
Medication for cholesterol, blood pressure or diabetes 1.0 1.6 4.8 0.4 -2.0 1.1 -0.2 0.7 0.6 2.2 -0.5 -1.8
Glaucoma (self-reported) 0.8 1.0 3.0 -0.9 0.4 0.7 -0.6 1.6 1.7 1.1 0.3 -0.0
Gout (self-reported) 0.5 0.6 2.3 0.3 0.5 -1.5 -1.1 -0.5 0.9 -0.8 0.0 0.3
Hypothyroidism/myxoedema (self-reported) 0.3 0.5 1.3 0.2 0.2 1.1 1.1 -0.1 -1.1 -0.7 0.3 -0.1
Medication: Amlodipine 0.4 0.5 2.1 -0.6 0.1 0.1 -1.4 0.7 -1.1 0.4 0.7 0.1
Medication: Ventolin 100micrograms inhaler 1.5 1.9 4.6 -1.4 1.1 -2.2 -1.8 -0.5 0.7 -1.4 1.3 1.3
Birth weight 0.7 1.5 4.8 2.0 -1.0 -0.7 -0.1 0.0 -0.8 1.2 -2.2 -1.2
Chronic bronchitis/emphysema (mother) 0.7 0.8 2.8 -1.2 1.2 0.3 -0.9 0.7 0.1 -0.1 1.7 0.7
High blood pressure (siblings) 1.2 1.7 4.0 -1.4 1.9 -0.4 -1.0 -0.0 0.3 -2.0 1.2 1.6
Forced vital capacity (FVC), Best measure 0.4 1.4 4.5 0.5 -0.4 -1.2 1.1 -1.7 -1.2 -0.7 -2.1 0.4
Body fat percentage 1.5 5.9 29.4 -2.7 2.6 -1.6 -5.4 0.4 1.2 -1.0 1.2 1.7
Leg fat percentage (right) 1.5 5.3 21.3 -2.8 2.8 -1.8 -4.6 -0.1 0.9 -1.2 1.4 1.9
Arm fat-free mass (right) 0.2 0.9 3.1 0.7 0.8 1.3 -0.9 -0.5 -1.8 0.4 -0.8 0.2
Exposure to tobacco smoke outside home 1.0 1.3 4.1 -0.3 1.2 0.4 0.8 2.0 2.0 0.1 -1.2 0.5
Comparative body size at age 10 0.4 1.2 5.5 -2.3 0.6 -0.3 -1.9 -0.0 0.5 1.0 0.3 0.6
Number of full brothers 0.9 1.1 5.2 2.3 -0.5 0.2 1.0 0.0 -1.5 0.8 -0.7 -0.7
Worry too long after embarrassment 0.9 1.5 6.0 -1.8 0.4 0.2 0.3 -0.8 0.0 -1.7 2.4 0.8
Seen a psychiatrist for nerves, anxiety, tension or depression 1.4 1.8 6.0 2.1 -1.1 0.9 1.0 0.6 -2.4 1.1 -0.4 -1.2
Wheeze or whistling in the chest in last year 0.8 1.5 4.5 -1.6 1.4 -1.3 -1.1 -0.5 -0.3 -2.1 -0.2 1.1
Number of children fathered 1.3 1.5 3.7 1.4 -1.1 1.8 -0.9 0.7 -0.5 1.9 -0.1 -1.3
Reason for reducing amount of alcohol drunk: Health precaution 0.4 0.5 2.7 0.1 -0.2 -0.6 0.2 1.6 0.4 0.7 -0.8 -0.5
Age at first live birth 1.1 1.9 5.1 1.0 -0.2 -2.3 0.8 -2.0 1.1 -1.8 -1.1 0.7
Pulse wave peak to peak time 0.9 1.0 2.6 -0.1 0.3 1.4 1.6 -1.1 -0.9 -0.5 1.3 0.6
Health satisfaction 0.4 0.5 2.0 1.4 -0.4 0.5 0.0 0.9 -0.7 0.5 -0.1 -0.8
Shortness of breath walking on level ground 1.6 1.9 8.2 -0.9 1.1 0.5 -1.0 2.9 2.2 0.5 0.5 0.6
Qualifications: College or University degree 0.8 2.6 9.9 2.2 -0.8 0.1 3.1 -2.4 -1.3 -0.7 0.3 -0.1
Eye problems/disorders: None of the above 0.6 0.6 1.3 0.5 0.9 -1.1 -0.5 -1.1 0.2 -0.9 0.5 0.9
Mouth/teeth dental problems: Loose teeth 0.3 0.4 1.9 -0.7 -0.0 -1.4 -0.6 -0.8 0.1 -0.4 -0.0 0.1
Emphysema/chronic bronchitis 0.6 0.6 1.5 -0.9 1.2 1.0 0.0 -0.1 0.2 -0.7 0.8 1.1
Medication for pain relief, constipation, heartburn 0.5 0.8 5.1 0.5 0.1 0.6 1.0 0.5 2.3 -0.1 0.8 0.2
Neck or shoulder pain in last month 0.4 0.6 1.6 -0.8 -0.6 0.4 -0.2 0.7 -1.3 0.8 1.1 -0.6
Medication: Blood pressure 0.5 0.9 2.0 -0.8 0.9 -1.3 -0.5 -0.8 -1.1 -1.4 0.4 0.9
Angina (self-reported) 1.0 1.3 2.8 -0.4 1.7 -0.7 -1.1 0.4 1.2 -1.3 0.9 1.6
Migraine (self-reported) 0.9 1.1 2.9 0.8 -0.9 1.7 0.8 1.3 -0.2 1.2 -0.4 -1.1
Medication: Ibuprofen 0.4 0.5 1.8 -0.9 0.3 -0.3 -1.4 -0.2 -1.0 -0.5 0.4 0.2
Medication: Allopurinol 0.9 1.3 2.5 -0.9 1.3 -1.6 -1.4 -0.3 1.0 -1.1 1.1 0.9
Medication: Omeprazole 0.5 0.6 2.2 -0.6 -0.7 -0.7 -0.5 -0.9 -1.5 0.5 -0.6 -0.5
Medication: Seretide 50 evohaler 1.4 1.7 3.8 -0.5 1.9 -1.2 -1.5 -0.8 0.5 -1.6 0.9 1.7
Mean time to correctly identify matches 0.6 1.2 4.0 0.1 -0.6 2.0 -0.2 1.1 -1.6 0.6 -0.5 -1.3
Heart disease (mother) 1.7 2.1 5.3 -0.3 2.0 -1.3 0.2 -1.6 -0.1 -2.1 0.8 2.3
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.6 0.7 1.6 1.2 -1.2 -0.5 -0.3 0.2 -0.3 0.7 -0.9 -1.3
Whole body fat mass 1.2 4.8 24.8 -2.2 2.8 -0.8 -5.0 0.3 0.6 -0.9 1.1 1.8
Leg fat mass (right) 1.2 4.5 19.9 -2.2 2.9 -0.9 -4.5 0.0 0.3 -1.1 1.2 1.9
Arm predicted mass (right) 0.2 0.9 3.5 0.7 1.1 1.4 -0.7 -0.4 -1.9 0.2 -0.5 0.6
Pulse rate, automated reading 0.6 1.8 3.4 -0.2 1.7 0.5 -1.3 1.8 1.8 -0.1 1.8 1.4
Alcohol intake frequency. 0.4 0.8 3.4 0.1 -0.7 1.0 0.2 -0.4 -1.9 1.2 0.2 -0.9
Comparative height size at age 10 0.1 0.7 1.9 1.1 0.4 -0.2 -1.3 -0.8 -1.4 -0.7 -0.7 0.1
Number of full sisters 1.0 1.2 6.8 0.9 0.8 1.2 2.6 -0.2 0.1 -0.8 0.2 0.5
Suffer from ‘nerves’ 0.6 1.0 2.0 -1.3 -1.3 -0.5 -0.8 -0.0 -0.7 1.4 -1.0 -1.2
Overall health rating 1.1 2.4 9.7 -0.9 0.9 -2.3 -3.1 0.1 -1.9 -1.1 -0.1 0.5
Chest pain or discomfort 1.0 1.5 4.4 0.3 2.1 -0.2 0.3 0.4 0.5 -2.0 1.2 1.7
Had major operations 1.9 2.2 6.8 2.2 0.7 1.0 2.6 -1.4 -0.9 -1.8 0.4 0.8
Age at last live birth 1.3 1.9 8.2 1.1 -1.6 -1.9 0.7 -2.9 0.2 -0.6 -1.0 -0.4
Family relationship satisfaction 0.5 0.6 2.4 0.2 -0.3 0.6 -0.6 1.6 1.2 0.6 -0.2 -0.7
Leg pain on walking 0.5 0.6 1.8 -0.2 1.1 0.0 -0.0 1.3 1.3 0.5 0.5 0.8
Qualifications: NVQ or HND or HNC or equivalent 0.8 0.9 2.4 -1.0 0.1 -1.5 -0.2 -0.8 -1.0 -0.9 -1.6 0.5
Commuting to job workplace: Car/motor vehicle 0.2 0.2 0.9 -0.4 -0.3 0.5 -1.0 0.4 -0.0 0.3 0.6 -0.1
Illness, injury, bereavement, stress in last 2 years 0.9 1.2 5.1 0.9 0.0 -2.3 -0.0 -1.2 1.5 -0.5 0.5 0.5
Medication: Aspirin 1.2 1.6 4.3 2.1 0.8 1.2 1.7 -0.4 -1.8 -1.2 -0.7 0.4
Supplements: Vitamin C 0.9 1.1 2.7 1.6 -1.1 0.8 1.3 -0.2 -0.3 0.8 -1.4 -1.0
Knee pain experienced in last month 1.1 1.7 6.7 0.5 1.0 -1.5 -2.6 -0.3 0.5 -0.3 2.0 0.8
Hypertension (Self-reported) 0.8 2.2 6.5 -1.5 1.7 -1.2 -2.6 -0.1 0.0 -1.0 1.6 1.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.7 2.0 4.6 -1.5 1.8 -1.5 0.3 -1.3 0.1 -1.5 1.1 2.1
Illnesses of father: Heart disease 2.8 3.9 10.8 0.3 3.3 -0.1 0.8 1.2 2.6 -1.6 2.2 2.8
Illnesses of siblings: Diabetes 0.4 0.5 0.9 0.5 0.9 -0.8 0.9 0.7 -0.5 -0.9 -0.5 0.6
Smoking status: Previous 0.5 0.7 1.8 0.5 -0.1 -1.2 0.0 1.3 1.1 0.3 -1.0 -0.5
Forced expiratory volume in 1-second (FEV1), predicted 2.1 4.4 14.7 0.5 -2.4 0.3 -0.2 1.1 -2.4 2.5 -3.8 -2.4
Whole body fat-free mass 0.2 1.1 3.3 0.6 1.8 1.5 -0.7 0.0 -1.4 -0.4 -0.2 1.2
Leg fat-free mass (right) 0.2 1.3 4.0 0.8 2.0 1.4 -1.6 0.4 -0.7 -0.6 0.2 1.3
Arm fat percentage (left) 1.8 7.1 28.4 -3.2 3.2 -1.3 -5.3 0.6 1.9 -1.4 1.7 2.2
Average weekly red wine intake 0.7 1.0 2.5 1.3 -0.6 1.6 1.3 0.8 1.2 0.6 0.2 -0.5
Handedness (chirality/laterality): Left-handed 3.8 4.6 11.2 0.3 -3.3 0.1 -0.1 0.7 -1.8 3.1 -2.4 -3.4
Mood swings 0.4 0.8 2.7 -0.1 -0.7 -0.7 0.5 0.1 -1.7 0.6 -1.2 -0.9
Loneliness, isolation 0.4 0.6 2.4 0.5 0.0 1.1 1.5 -0.3 -1.1 0.1 0.2 -0.0
Long-standing illness, disability or infirmity 1.2 1.8 6.2 -1.5 1.5 -1.0 -2.5 0.3 -1.2 -0.7 1.2 0.9
Ever had bowel cancer screening 1.2 1.4 3.1 -0.4 1.7 -0.4 0.1 -0.8 -0.1 -1.8 1.7 1.7
Diabetes diagnosed by doctor 1.6 2.6 6.1 -2.2 2.2 0.6 -0.7 0.0 -1.0 -2.5 1.6 1.8
Ever had stillbirth, spontaneous miscarriage or termination 0.7 0.7 2.5 -0.7 -0.8 -0.1 -0.8 1.6 0.9 0.7 -0.7 -0.7
Friendships satisfaction 0.4 0.5 1.2 -1.0 1.1 -0.5 -0.4 -0.2 0.4 -0.3 0.8 1.0
Qualifications: nursing, teaching 0.4 0.7 3.2 0.9 -0.4 0.9 1.8 -0.1 -0.3 0.7 0.2 -0.6
Commuting to job workplace: Walk 0.6 0.7 3.3 -1.8 -0.1 -1.0 -0.8 -0.2 0.4 -0.4 -0.8 0.1
Eye problems/disorders: Cataract 0.4 0.5 2.2 -0.0 -0.4 -0.6 -1.5 0.7 0.8 0.2 -0.1 -0.4
Mouth/teeth dental problems: Mouth ulcers 0.3 0.5 2.2 -1.2 0.4 -1.5 -0.5 -0.7 0.3 -0.3 -0.3 0.4
Medication for cholesterol 0.7 1.0 4.7 0.5 -0.7 -0.8 2.2 -1.3 0.2 -0.4 -1.2 -0.3
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.5 1.8 6.2 -0.9 -1.2 -0.9 -2.0 -0.6 -2.5 1.1 -0.8 -0.8
Back pain experienced in last month 1.3 1.9 6.2 -1.2 1.8 -0.9 -2.5 1.3 0.2 -0.3 1.5 1.2
Mineral and other dietary supplements 1.4 1.9 4.4 -2.1 1.0 -1.2 -1.8 0.3 1.2 -0.3 1.9 1.4
Breast cancer (self-reported) 0.5 0.6 1.5 -0.8 0.5 0.4 0.7 -1.2 -0.7 -1.1 0.2 0.8
Asthma (self-reported) 0.9 1.9 5.1 -1.5 1.2 -0.0 -1.9 2.2 1.8 -0.1 1.1 0.5
Osteoporosis (self-reported) 0.9 1.1 5.0 0.6 -0.8 -0.6 -0.6 -0.5 -1.6 -0.1 -2.2 -0.4
Osteoarthritis (self-reported) 0.2 0.2 1.1 -0.3 0.2 -0.5 -1.1 -0.3 -0.4 0.1 0.2 0.0
Medication: Aspirin 1.4 1.8 5.9 2.4 0.7 1.0 2.0 -0.5 -1.4 -1.2 -0.8 0.5
Medication: Gliclazide 2.8 3.2 8.8 -0.2 3.0 -0.7 -0.9 0.2 1.1 -2.5 2.0 2.6
Illnesses of father: None of the above (group 1) 0.7 0.9 2.5 0.0 -1.6 -0.8 -0.1 -0.7 -1.4 0.6 -0.8 -1.3
Smoking status: Current 0.4 0.7 1.6 1.3 -1.1 0.5 -0.2 0.3 -1.1 0.5 -0.1 -1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.3 0.6 2.3 -0.4 0.6 -1.5 0.3 -0.8 0.1 -0.9 0.2 0.9
Whole body water mass 0.2 1.1 3.1 0.6 1.8 1.4 -0.6 -0.1 -1.4 -0.4 -0.3 1.2
Leg predicted mass (right) 0.2 1.3 4.0 0.9 2.0 1.4 -1.5 0.3 -0.8 -0.6 0.2 1.3
Arm fat mass (left) 1.2 4.9 21.2 -2.4 3.0 -0.4 -4.6 0.6 0.9 -1.0 1.2 2.0
Number of self-reported non-cancer illnesses 1.4 2.4 4.8 -1.1 1.9 -1.3 -0.7 -0.9 -1.5 -2.2 1.9 1.9
Average weekly champagne plus white wine intake 0.8 1.1 2.5 0.1 0.7 -1.2 0.3 -1.6 -0.5 -1.1 1.2 1.5
Miserableness 0.3 0.5 1.9 -0.0 0.7 -0.3 1.4 -0.2 -1.0 -0.9 -0.3 0.4
Guilty feelings 0.8 1.3 3.1 0.2 -1.6 1.8 1.2 0.5 -0.7 1.1 -0.4 -1.4
Wears glasses or contact lenses 0.9 1.0 3.3 -1.8 1.1 -0.6 -1.1 0.7 0.4 -0.6 1.0 0.8
Ever taken oral contraceptive pill 2.5 2.7 7.3 -0.2 1.7 0.3 1.6 -1.5 1.2 -2.7 1.7 2.3
Hearing aid user 0.8 0.9 2.9 -0.7 1.3 1.7 0.6 0.4 0.6 -0.4 1.4 0.8
Mother’s age at death 1.4 1.8 6.0 1.4 -0.3 1.8 0.2 2.5 1.7 0.4 0.4 -1.1
Financial situation satisfaction 0.5 0.6 2.0 -0.0 1.4 -0.1 0.0 -0.4 0.2 -1.0 -0.8 1.1
Tinnitus: Yes, now most or all of the time 0.4 0.5 1.3 -0.2 1.2 0.7 0.2 1.0 -0.1 -0.7 -0.3 0.9
Commuting to job workplace: Public transport 0.1 0.1 0.7 0.2 0.1 -0.2 0.8 -0.1 0.6 -0.3 -0.0 0.1
Eye problems/disorders: Glaucoma 0.3 0.4 1.9 -0.3 -0.0 1.4 0.9 0.4 0.4 0.5 0.3 -0.1
Medication: Blood pressure 0.4 0.7 2.6 -0.9 0.7 0.3 -1.6 0.9 -0.5 -0.1 0.9 0.5
Pain type(s) experienced in last month: Hip pain 1.7 2.2 6.4 -2.5 0.7 0.8 -1.8 2.1 1.6 1.1 0.9 -0.0
Supplements: Fish oil (including cod liver oil) 1.0 1.3 3.8 1.4 -0.5 1.9 1.6 0.6 -0.6 0.6 -0.9 -1.3
High cholesterol (Self-reported) 0.3 0.5 2.3 0.5 0.4 -0.3 -0.9 -0.0 -1.5 -0.3 0.7 0.4
Medication: Bendroflumethiazide 0.6 0.8 3.1 0.1 -0.3 0.0 -1.3 0.6 -1.8 0.6 -1.2 -0.7
Medication: Paracetamol 1.2 1.8 5.1 -0.9 1.9 -0.6 -0.4 -1.2 -0.1 -1.7 1.5 2.2
Medication: Lisinopril 0.8 1.1 3.0 -1.2 0.9 -1.7 -1.6 0.2 0.5 -0.9 -0.3 0.7
Medication: Atorvastatin 0.7 0.8 2.4 0.2 0.4 -0.7 -1.5 1.2 1.4 0.2 0.9 0.3
Illnesses of father: High blood pressure 0.7 0.9 3.0 -1.5 0.8 -0.5 -1.7 0.7 0.8 -0.4 0.2 0.7
Alcohol drinker status: Never 2.0 2.4 5.7 1.5 -1.6 2.4 1.3 0.9 -0.8 1.8 -1.2 -1.8
Ever smoked 0.6 1.0 4.9 2.2 -1.0 -0.4 0.8 0.5 -0.2 0.3 -0.8 -1.2
Basal metabolic rate 0.2 1.2 4.5 0.2 2.1 1.1 -1.4 0.0 -1.1 -0.5 -0.1 1.4
Leg fat percentage (left) 1.3 4.9 21.6 -2.4 2.6 -1.8 -4.7 0.1 1.1 -0.8 1.2 1.8
Arm fat-free mass (left) 0.2 1.1 3.4 0.7 1.8 1.5 -0.9 0.1 -1.3 -0.2 -0.2 1.1
Number of operations (self-reported) 1.6 2.3 4.4 1.5 1.6 0.9 1.5 -1.0 0.5 -2.0 2.1 2.0
Average weekly beer plus cider intake 0.6 0.9 2.8 -0.2 -0.8 0.9 -0.1 0.6 -1.7 -0.1 -1.3 -1.2
Irritability 0.6 1.1 2.7 -0.7 -0.7 -0.4 -1.0 1.5 -0.2 1.6 -1.2 -1.1
Risk taking 2.2 3.2 7.0 1.9 -2.5 0.4 -0.8 0.9 -0.3 1.9 -2.5 -2.6
Ever had prostate specific antigen (PSA) test 1.4 1.7 5.7 -1.1 0.6 -1.2 -0.2 -2.4 -0.0 -2.1 0.7 1.1
Fractured/broken bones in last 5 years 0.8 1.1 3.5 1.1 -1.0 -0.8 0.0 -1.5 -1.9 -0.5 -0.8 -0.2
Age started oral contraceptive pill 0.5 0.6 2.9 0.2 0.6 -0.1 0.4 -0.8 1.7 -0.4 1.0 0.6
Diastolic blood pressure, automated reading 2.1 6.6 14.3 -3.2 3.1 -3.8 -2.4 -1.4 1.4 -2.0 0.9 3.3
Ever depressed for a whole week 1.7 2.1 4.8 0.5 -1.7 1.2 -0.5 1.6 -1.5 1.8 -0.9 -2.2
Unable to work because of sickness or disability 0.3 0.4 1.1 -0.4 1.1 -0.3 -1.0 0.4 -0.1 -0.2 0.2 0.7
Commuting to job workplace: Cycle 0.5 0.6 2.6 -0.8 0.1 -0.9 -0.0 -1.6 0.6 -0.5 0.6 0.5
Myopia 0.5 0.7 2.5 -1.6 0.2 -1.4 -0.0 0.6 1.0 0.1 0.7 0.0
Vascular/heart problems diagnosed by doctor 0.9 2.5 6.8 1.5 -2.0 1.4 2.6 -0.1 -0.4 1.4 -1.4 -2.0
Cholesterol lowering medication 0.5 0.8 2.2 0.5 0.1 1.1 -1.5 0.6 -1.3 0.7 0.7 -0.1
Medication: Omeprazole (e.g. Zanprol) 0.4 0.5 1.2 -0.5 -0.9 -0.4 -0.2 -0.9 -1.1 0.8 -0.4 -0.7
Pain experienced in last month 0.4 0.6 2.9 -0.6 -0.1 0.5 1.7 -0.6 1.2 -0.3 -0.2 0.3
Supplements: Calcium 1.3 1.4 4.3 0.2 1.4 0.4 1.8 -1.0 -0.8 -2.1 0.2 1.1
Basal cell carcinoma (self-reported) 0.6 0.7 2.4 -1.1 -0.4 -0.5 -0.9 -1.6 -0.6 -0.6 -0.5 0.4
Heart attack/myocardial infarction (self-reported) 0.8 1.1 2.9 0.5 1.4 -0.1 0.6 -0.5 0.2 -1.6 1.7 1.2
Deep venous thrombosis (DVT) (self-reported) 1.1 1.4 3.6 0.3 1.3 0.8 1.1 -1.4 -0.6 -1.9 0.6 1.6
Heart disease (siblings) 0.3 0.3 0.9 0.5 -0.0 0.7 0.1 0.8 0.9 0.2 0.7 -0.3
Alcohol drinker status: Previous 1.6 1.8 5.6 1.7 -1.4 0.4 1.3 -0.9 -2.4 1.1 -0.5 -1.4
Pack years of smoking 0.5 0.8 1.7 0.6 -1.1 0.5 -1.3 -0.3 -0.7 1.1 0.0 -1.3
Impedance of whole body 0.3 1.4 4.9 0.0 -2.0 -2.2 -0.4 -0.2 0.4 0.4 -1.1 -1.3
Leg fat mass (left) 1.2 4.6 22.0 -2.2 2.8 -1.1 -4.7 -0.0 0.4 -1.0 1.1 1.9
Arm predicted mass (left) 0.2 1.0 3.0 1.1 1.4 1.3 -0.6 -0.2 -1.7 0.0 -0.7 0.7