Hub : Genes

EPT1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Colon Sigmoid	0.1070	0.0490	6.2e-03	-0.003	NA	-0.005	NA	-0.008	4.2e-01	NA	5.1e-01	NA	7.8e-01
2	GTEx	Muscle Skeletal	0.0981	0.0339	8.5e-04	0.031	NA	0.035	NA	0.041	4.2e-04	NA	2.2e-04	NA	6.1e-05
3	GTEx	Pituitary	0.3220	0.0970	4.5e-04	0.012	NA	0.054	NA	0.034	1.6e-01	NA	1.8e-02	NA	4.9e-02
4	GTEx	Prostate	0.2090	0.0860	4.2e-03	-0.010	NA	0.000	NA	-0.011	7.1e-01	NA	3.2e-01	NA	7.5e-01
5	GTEx	Skin Sun Exposed Lower leg	0.0830	0.0360	4.5e-03	0.036	NA	0.035	NA	0.029	5.8e-04	NA	6.9e-04	NA	1.9e-03
6	METSIM	Adipose	0.0478	0.0249	4.4e-03	0.000	0.008	0.016	0.012	0.001	3.9e-01	0.02100	1.6e-03	0.0049	2.2e-01
7	ROSMAP	Brain Pre-frontal Cortex	0.0728	0.0248	3.9e-05	0.056	0.024	0.048	0.009	-0.001	8.9e-08	0.00040	6.9e-07	0.0240	5.9e-01
8	TCGA	Kidney Renal Clear Cell Carcinoma	0.0329	0.0189	1.9e-03	0.006	0.014	0.019	NA	0.016	7.0e-02	0.00820	3.0e-03	NA	5.2e-03
9	TCGA	Testicular Germ Cell Tumors	0.1680	0.0720	4.4e-05	0.156	0.102	0.118	NA	0.154	3.7e-06	0.00019	5.9e-05	NA	4.2e-06

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.7	1.1	4.3	0.3	0.5	0.4	-0.3	2.1	1.5	1.5	0.5	0.3
Bipolar Disorder or Schizophrenia	0.9	2.2	4.6	-1.3	0.6	-0.2	-2.1	2.1	2.1	1.6	1.3	0.5
Depressed Affect (Nagel 2018)	0.1	0.2	0.9	0.4	-0.0	-1.0	0.2	-0.1	-0.6	0.6	-0.3	-0.0
Depression (Nagel 2018)	0.2	0.3	0.9	0.9	-0.3	0.6	0.3	0.0	-0.8	0.5	0.2	-0.2
Intelligence (Savage-Jansen 2018)	0.2	0.6	1.9	0.9	-0.2	-1.4	1.1	-0.8	0.2	0.7	0.4	0.0
Neuroticism (Nagel 2018)	0.4	1.0	2.0	-0.6	-1.4	-0.4	-1.0	0.9	-1.1	1.3	-0.4	-1.3
Schizophrenia (2018)	0.9	1.8	6.2	-1.9	0.4	-0.6	-2.5	1.1	1.6	0.7	1.2	0.4
Schizophrenia vs Biploar Disorder	0.6	0.8	2.0	-1.3	0.4	0.8	-1.4	0.2	0.3	-1.1	0.8	0.4
Worry (Nagel 2018)	1.5	3.3	5.9	-2.2	-2.4	0.3	-2.3	1.2	-1.4	2.2	-0.3	-2.3
Alzheimer’s Disease (in mother)	1.2	1.5	4.0	0.5	-2.0	1.7	0.5	0.3	-1.0	1.1	-0.7	-1.7
Alzheimer’s Disease (in father)	0.9	1.0	3.6	-0.4	-1.5	1.9	-0.2	-0.3	-0.7	1.3	-0.2	-0.9
Alzheimer’s Disease (including proxy)	1.3	1.9	5.8	-0.3	-2.1	2.4	0.1	0.2	-0.7	1.7	-0.4	-1.6
Crohns Disease (2017)	0.1	0.2	0.7	-0.1	-0.3	-0.3	-0.4	0.1	0.4	0.5	0.8	0.0
Irritable Bowel Disease (IBD)	0.1	0.1	0.4	0.0	-0.4	-0.7	-0.3	-0.6	-0.2	0.4	-0.1	0.1
Ulcerative Colitis (UC)	0.2	0.3	1.3	0.2	-0.3	-0.8	-0.0	-1.1	-0.5	0.0	-0.6	0.2
Major Depression (MDD)	1.2	1.5	3.8	-1.9	0.9	-1.5	-0.9	0.4	1.8	-0.7	0.9	1.0
Reaction Time	0.7	1.4	4.7	0.4	-0.9	2.2	0.4	1.1	-1.6	0.9	-0.8	-1.4
Verbal and Numeric Reasoning (VNR)	0.2	0.5	1.5	0.7	-0.3	-0.5	0.6	0.7	0.5	1.2	1.0	-0.4
Breast Cancer	0.7	1.6	4.2	2.0	-0.0	-2.0	-1.2	-0.8	-0.7	0.2	-1.8	0.0
Ovarian Cancer	0.3	0.4	1.4	0.0	-0.1	0.1	0.0	-0.7	-1.2	-0.5	1.0	-0.1
Prostate Cancer	0.4	0.5	1.3	-0.3	-0.4	-0.2	-1.1	1.1	-0.4	0.6	-0.9	-0.7
Age at First Birth	0.4	0.6	1.3	-1.0	0.9	-1.1	-0.8	0.7	0.5	-0.8	0.4	0.6
Bipolar Disorder (2011)	1.1	1.0	3.0	0.5	0.9	0.8	0.0	1.7	1.3	1.0	1.2	0.7
Body Mass Index (BMI) (2010)	0.3	0.4	2.1	1.4	-0.1	0.4	-0.7	-0.1	0.1	0.5	-0.7	0.0
Coronary Artery Disease (CAD)	1.4	1.6	3.2	-1.7	1.3	1.6	-0.2	0.5	1.8	-0.6	1.6	1.1
Crohns Disease (2012)	0.4	0.7	2.3	-0.6	0.5	0.2	-0.1	0.8	1.4	0.4	1.5	0.5
Mean Putamen Volume	0.6	0.7	1.5	0.5	1.1	-0.6	0.4	-1.2	-0.0	-1.2	0.3	1.2
Fasting Glucose	1.7	2.1	5.0	-0.9	-2.2	0.7	0.7	-0.2	-1.5	1.6	-1.6	-2.2
HbA1C	0.8	0.9	3.8	-1.9	-0.4	-1.0	-1.3	-1.2	-0.3	-0.1	0.1	0.2
HDL Cholesterol	1.5	2.5	6.0	0.9	-2.1	1.9	0.7	1.6	-0.0	1.9	-1.2	-2.4
LDL Cholesterol	1.5	2.4	5.1	1.3	1.9	0.6	1.8	-1.2	1.0	-1.8	1.5	2.3
Lupus	0.2	0.2	0.7	0.6	-0.4	-0.7	0.9	-0.4	0.0	-0.3	-0.3	-0.3
Neuroticism (2016)	0.7	0.9	2.6	-1.6	1.4	0.9	0.1	0.1	-0.2	-0.8	1.2	1.0
Primary Biliary Cirrhosis	0.6	0.9	3.1	-1.1	-0.9	0.0	-1.8	0.1	-0.2	1.0	-0.9	-1.0
Rheumatoid Arthritis	0.9	1.2	3.8	0.5	-1.5	-0.6	1.2	-1.1	-0.9	-0.1	-1.9	-0.9
Schizophrenia (2014)	0.7	1.6	5.4	-2.3	0.8	-0.3	-2.0	0.6	1.4	0.2	1.2	0.9
Triglycerides	0.3	0.4	2.0	0.4	-0.3	-1.4	-0.4	0.1	0.5	0.6	-0.9	0.1
Type 2 Diabetes (T2D) (2012)	2.2	2.5	7.0	0.2	2.6	-0.9	-0.0	0.1	2.5	-0.9	1.0	2.6
Ulcerative Colitis	0.2	0.3	0.8	0.3	-0.0	-0.8	-0.9	-0.7	0.1	0.2	-0.4	0.4
Blood Eosinophil Count	0.2	1.8	5.2	-0.5	-0.1	-2.3	-1.6	-1.6	-1.1	-0.8	-1.9	0.3
Blood Platelet Count	0.4	4.5	14.3	-3.8	1.4	-3.5	-2.5	-0.6	1.6	-0.7	0.5	1.5
Blood Red Count	0.4	3.6	12.2	-3.5	2.3	-1.5	-1.6	-1.6	1.2	-0.6	0.2	2.3
Blood White Count	0.5	4.0	12.9	-2.3	1.5	-3.6	-1.5	-2.1	0.2	-2.4	-0.1	1.8
Heel T-Score	0.3	2.0	11.3	-1.8	0.8	-0.5	-3.4	0.9	-0.2	-0.3	1.2	0.0
BMI	0.3	1.9	9.0	-0.2	2.0	0.8	-3.0	1.1	0.8	0.0	0.5	1.1
Height	0.2	3.6	11.9	3.1	-1.0	0.9	1.0	-0.6	-3.5	-0.8	-2.4	-1.1
Waist Hip Ratio (WHR)	0.6	2.6	9.7	-0.6	-1.9	-0.5	-3.1	-1.3	-2.1	0.6	-0.2	-1.7
Systolic Blood Pressure	0.3	1.4	5.7	-2.4	0.3	-1.6	-0.7	-0.9	-1.1	-1.0	-0.6	0.6
Smoking Status	0.2	0.5	2.8	1.7	-0.3	-0.0	0.4	0.7	0.6	-0.0	0.3	-0.6
Allergy or Eczema	0.3	0.7	2.3	-0.4	1.3	-0.3	-0.8	0.8	0.8	-1.5	-0.1	0.5
Cardiovascular Disease	0.2	0.5	2.1	0.0	0.7	0.2	-1.4	0.7	-0.8	0.5	0.3	0.7
Hypothyroidism (self reported)	0.4	1.0	3.6	0.6	0.4	1.9	1.6	0.8	-0.5	-0.6	0.7	-0.3
Respiratory disease	1.3	2.9	5.8	-1.9	1.8	0.4	-2.1	2.4	2.0	-1.0	1.7	1.1
Type 2 Diabetes (T2D) (2018)	0.6	1.0	3.3	-1.8	1.1	1.3	-0.6	0.6	-0.6	-0.5	1.1	0.7
Lung FEV1/FVC ratio	0.3	1.8	4.2	0.9	1.7	1.6	0.6	2.0	1.3	1.3	0.9	0.9
Lung FVC	0.6	2.8	9.0	-0.5	-0.0	-2.4	1.7	-3.0	-0.1	-2.4	-1.4	0.5
Neuroticism	0.2	0.6	2.6	-0.5	-0.7	-0.3	0.4	-1.0	-1.6	-0.6	-0.1	-0.3
Chronotype (morning person)	0.4	1.0	4.8	-0.2	0.1	0.6	2.2	-0.4	-1.6	0.5	-1.1	0.1
Hair Pigment	0.1	2.1	8.3	0.9	0.5	-1.1	-0.1	-2.5	-1.3	-2.9	-0.4	0.3
Tanning	0.2	2.5	10.8	-0.6	1.3	1.8	-0.2	0.8	1.9	-0.4	3.3	1.4
Hand grip strength (left)	1.5	4.0	7.7	1.5	-2.6	1.7	1.4	0.6	-0.5	2.8	-2.7	-2.4
Number of treatments/medications taken	1.0	1.7	7.3	-0.6	1.0	-0.8	-1.1	-1.3	-2.7	-1.2	0.9	1.1
Average weekly spirits intake	0.3	0.4	0.8	-0.3	0.8	0.1	-0.8	0.9	0.9	-0.7	-0.0	0.2
Sensitivity / hurt feelings	0.4	0.8	1.3	-1.1	-0.8	-1.2	-1.0	-0.2	-1.1	-0.4	-0.8	-0.7
Frequency of depressed mood in last 2 weeks	0.3	0.5	2.2	1.0	0.1	0.8	0.2	0.5	-1.5	0.4	-0.2	-0.3
Hearing difficulty/problems: Yes	0.3	0.5	1.5	0.6	0.9	-1.2	-0.6	-0.4	-0.3	-0.4	-0.5	0.9
Relative age of first facial hair	0.5	0.9	2.6	1.4	1.0	0.1	1.6	-0.5	0.7	-0.6	0.5	1.2
Other serious medical condition/disability diagnosed by doctor	2.1	2.7	5.5	-0.9	1.8	-1.3	0.7	-2.1	-1.1	-2.4	1.3	2.2
Ever used hormone-replacement therapy (HRT)	2.1	2.7	4.9	2.1	-1.4	1.9	1.0	1.4	-2.2	1.5	-0.4	-2.0
Ever had hysterectomy (womb removed)	0.5	0.6	3.0	-0.3	0.4	-0.5	-1.7	-0.6	0.9	0.1	0.5	0.6
Systolic blood pressure, automated reading	1.0	2.9	6.1	-2.4	1.7	-1.9	-1.8	-1.0	0.6	-2.5	0.4	1.7
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	2.3	-0.0	1.5	0.7	0.2	1.5	0.6	-0.9	0.7	1.0
Angina	1.0	1.3	3.0	-0.6	1.7	-0.8	-1.1	0.7	1.2	-1.2	0.6	1.6
Medication for hormone replacement therapy	1.3	1.4	3.3	-1.8	1.4	0.8	-1.2	0.6	0.5	-0.4	1.8	1.2
Vitamin and mineral supplements	0.7	0.9	2.4	-0.7	1.2	-0.0	-0.6	-0.5	0.8	-0.4	1.5	1.5
Supplements: Zinc	0.9	1.0	2.7	1.3	-0.6	0.5	1.5	-0.8	-0.7	0.2	-1.6	-0.7
Medication: Co-codamol	1.6	1.8	7.6	-0.9	1.0	1.6	-0.9	1.6	0.8	0.6	2.8	0.5
Medication: Metformin	0.5	0.7	1.7	-1.2	0.8	-0.3	-1.3	0.8	-0.2	-0.7	0.7	0.4
Diabetes (father)	2.9	3.5	10.8	-1.0	2.4	-2.2	-0.9	-1.5	-0.3	-3.3	-0.6	2.5
Diabetes (mother)	0.8	1.1	2.4	1.4	0.9	1.4	1.2	-0.3	-0.2	-1.6	-0.2	0.9
Severe depression (siblings)	1.0	1.1	1.7	-1.2	1.2	-0.1	-0.6	1.2	1.1	-1.0	1.3	1.0
Pack years adult smoking proportion	0.8	1.2	2.6	0.2	-1.5	0.5	-1.5	-0.3	-0.9	1.6	-0.1	-1.6
Impedance of leg (right)	0.4	1.9	4.8	-0.9	-2.2	-2.1	0.3	-0.9	-0.6	0.8	-1.6	-1.5
Leg fat-free mass (left)	0.3	1.7	5.8	-0.0	2.4	1.0	-2.0	0.0	-0.9	-1.0	0.4	1.6
Trunk fat percentage	1.5	5.9	30.4	-2.3	2.7	-1.5	-5.5	0.5	1.5	-1.1	1.3	1.7
Hand grip strength (right)	0.8	2.0	5.7	0.7	-1.6	1.0	1.7	-0.8	-1.6	1.0	-2.4	-1.3
Townsend deprivation index at recruitment	0.6	0.8	1.9	0.6	1.3	1.4	0.9	-0.5	-0.6	-0.9	-0.2	1.1
Current tobacco smoking	0.6	1.0	2.3	1.5	-1.4	0.4	-0.1	0.2	-1.3	0.6	-0.4	-1.4
Average weekly fortified wine intake	0.4	0.4	2.4	0.4	-0.5	0.2	-0.0	0.2	1.6	0.5	-0.6	-0.7
Maternal smoking around birth	0.4	0.5	2.5	-0.5	0.5	-0.8	-1.6	-0.5	0.3	0.5	0.5	0.6
Fed-up feelings	0.1	0.2	0.5	0.6	-0.3	0.0	0.7	0.1	-0.6	0.7	-0.1	-0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.6	2.6	-0.0	-0.2	0.6	-0.1	0.5	-1.6	1.1	0.5	-0.5
Relative age voice broke	0.4	0.6	3.8	1.9	-0.5	0.1	0.9	-0.7	0.3	0.2	0.4	-0.2
Taking other prescription medications	0.5	0.8	2.5	0.0	0.7	0.0	0.0	-1.1	-1.6	-0.9	1.2	0.8
Age when periods started (menarche)	1.2	2.8	10.2	1.8	-1.7	3.2	1.5	1.4	-0.5	1.1	-0.1	-1.7
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	1.7	0.4	1.3	0.2	0.5	-0.0	0.6	-0.9	0.8	1.1
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.2	2.5	1.4	-0.7	1.6	1.5	0.8	-0.2	1.1	0.5	-1.2
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	1.3	1.1	-0.1	1.1	0.3	-0.2	-0.5	-0.1	0.4	-0.1
Qualifications: CSEs or equivalent	1.4	1.8	6.2	-2.5	1.9	0.5	-0.3	-0.4	-0.5	-0.5	1.4	1.9
Serious illness, injury or assault to yourself	1.1	1.4	2.9	-1.3	0.5	-1.2	-0.6	-1.5	-1.7	-1.5	0.3	1.1
High blood pressure	0.8	2.4	8.3	-1.7	1.5	-1.2	-2.9	-0.1	-0.1	-1.2	1.4	1.6
Hayfever, allergic rhinitis or eczema	0.5	1.1	4.4	-0.2	1.7	-0.0	-0.3	0.1	0.6	-2.1	0.7	1.2
Multivitamins +/- minerals	0.3	0.3	1.2	-0.7	0.0	-0.4	-0.0	0.2	-1.1	-0.5	-0.9	-0.5
Stomach or abdominal pain in last month	0.5	0.6	2.5	-0.4	-1.1	-0.2	0.5	-0.4	-1.6	0.5	-0.4	-0.8
Supplements: Glucosamine	2.2	2.9	8.1	0.9	-2.3	-1.0	-0.4	-1.0	-1.8	1.2	-2.9	-2.1
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	2.0	-0.3	0.4	1.1	1.4	0.4	-0.5	-0.8	0.9	-0.1
Medication: Atenolol	0.2	0.2	0.7	-0.1	0.8	-0.3	-0.2	0.3	-0.5	-0.3	0.5	0.5
Medication: Levothyroxine sodium	0.2	0.4	2.2	-0.1	-0.3	0.6	0.3	0.4	-1.5	-0.3	-0.1	-0.8
Sitting height	0.2	1.6	5.3	1.6	-0.9	1.5	0.4	0.0	-2.3	0.7	-1.4	-0.9
Chronic bronchitis/emphysema (father)	0.4	0.5	2.2	-0.4	0.8	-0.3	-1.5	0.6	0.9	-0.3	-0.3	0.5
High blood pressure (mother)	0.4	0.6	1.4	-0.8	-0.0	-1.0	-1.0	-1.2	-0.8	0.2	0.5	0.3
Body mass index (BMI)	1.2	5.0	15.0	-2.1	3.5	-0.3	-3.9	0.7	1.1	-1.2	1.9	2.4
Impedance of leg (left)	0.5	2.6	8.1	-0.3	-2.8	-2.0	0.3	-0.6	-0.4	1.6	-2.0	-2.1
Leg predicted mass (left)	0.3	1.7	5.6	0.0	2.4	1.0	-2.1	0.0	-0.9	-1.0	0.3	1.6
Trunk fat mass	1.1	4.8	26.1	-1.9	2.7	-1.0	-5.1	0.5	0.9	-0.9	0.9	1.6
Waist circumference	1.3	4.7	25.8	-1.9	2.6	-0.6	-5.1	0.6	0.4	-0.9	1.4	1.6
Number of incorrect matches in round	0.5	0.8	3.2	-0.4	0.1	-0.4	-1.0	-0.5	-1.6	-1.8	0.2	0.4
Past tobacco smoking	0.2	0.3	1.2	-0.5	-0.1	1.1	0.0	-0.6	-0.8	0.2	0.4	0.2
Alcohol usually taken with meals	0.5	0.9	2.1	0.8	0.3	0.4	1.3	-1.2	1.5	-0.3	0.8	0.9
Nervous feelings	1.8	3.3	9.1	-1.3	-3.0	-0.0	-1.3	0.4	-2.5	1.5	-1.1	-2.7
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	2.3	1.1	-0.4	1.5	0.9	0.9	0.3	1.1	0.5	-0.7
Hearing difficulty/problems with background noise	0.6	0.9	3.1	-0.4	0.9	-1.8	-0.0	-0.5	-0.7	-1.0	-1.3	0.8
Hair/balding pattern: Pattern 2	2.1	2.6	6.9	-0.7	2.6	-0.7	0.0	0.3	2.2	-1.2	1.9	2.5
Had menopause	0.6	0.8	1.7	0.7	-0.3	1.3	-0.8	1.2	-0.7	1.1	0.6	-0.7
Had other major operations	0.3	0.4	1.5	0.8	0.4	-0.6	0.3	-0.1	1.2	-0.6	0.7	0.6
Forced vital capacity (FVC)	0.5	1.9	6.5	1.0	-0.7	-1.1	1.3	-1.8	-1.4	-0.7	-2.5	-0.0
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.6	1.6	1.3	-0.5	1.1	0.8	-0.5	-0.6	0.3	0.7	-0.6
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	1.5	0.6	-0.3	1.2	0.3	0.6	-1.0	0.4	0.1	-0.8
Qualifications: None of the above	0.7	1.5	3.4	-1.0	1.4	0.4	-1.3	1.7	1.8	-0.2	1.3	0.7
Financial difficulties in last 2 years	0.4	0.6	1.6	0.2	0.9	1.3	-0.7	1.0	-0.3	0.9	-0.3	0.3
Mouth/teeth dental problems	0.5	0.7	2.2	-0.6	-1.0	-0.8	-1.5	0.5	-0.1	1.2	-0.1	-0.7
Heart attack	0.8	1.0	3.1	0.3	1.4	-0.3	0.5	-0.5	0.2	-1.5	1.8	1.2
Allergy	1.3	2.9	7.1	0.8	-2.7	0.1	0.4	-0.3	-1.8	2.5	-2.0	-2.2
Pain all over the body in last month	0.9	1.0	4.0	0.4	-0.3	-1.2	-2.0	-1.3	-1.0	0.3	-0.6	-0.0
Diabetes (self-reported)	1.4	2.2	5.1	-2.3	2.0	0.3	-1.0	0.6	-0.2	-1.9	1.7	1.6
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.4	-0.3	-0.0	0.0	-0.6	0.2	-0.3	-0.6	0.4	-0.3
Medication: Ramipril	0.9	1.1	3.4	-0.1	1.8	-0.3	0.5	-0.5	-0.4	-1.8	0.4	1.6
Medication: Simvastatin	0.7	1.0	2.0	-0.5	1.3	-0.7	-1.4	-0.5	-0.8	-1.4	0.7	1.1
Fluid intelligence score	0.4	0.8	3.1	1.0	-0.8	-0.4	1.0	0.4	0.7	1.8	0.5	-0.9
Illnesses of siblings	0.6	0.8	1.5	1.2	-1.2	0.6	0.7	-0.7	-1.1	0.9	-0.6	-0.7
Neuroticism score	0.3	0.5	2.0	-1.4	-0.7	-0.2	-0.2	0.0	-1.4	-0.0	-0.0	-0.7
Weight	0.6	3.1	13.2	-0.8	2.9	0.2	-3.6	0.5	-0.1	-0.9	0.9	1.9
Impedance of arm (right)	0.2	1.2	5.4	-0.7	-0.2	-2.3	-1.2	0.0	1.6	-0.8	0.2	0.2
Arm fat percentage (right)	1.9	7.6	27.8	-3.2	3.5	-1.3	-5.3	0.6	1.9	-1.6	1.9	2.5
Trunk fat-free mass	0.2	1.0	2.8	0.6	1.4	1.6	0.1	-0.1	-1.7	-0.1	-0.6	0.9
Hip circumference	1.1	4.6	13.7	-1.3	3.5	-0.2	-3.7	1.7	1.7	-1.0	1.4	2.3
Time employed in main current job	0.5	0.6	2.3	0.0	0.3	0.0	-0.5	0.7	-0.4	-1.5	1.4	0.1
Alcohol intake versus 10 years previously	0.8	1.2	2.2	1.1	-1.1	1.5	0.5	-0.2	-1.4	1.3	-0.4	-1.4
Father’s age at death	1.1	1.5	3.8	0.7	-1.9	1.0	-1.1	0.7	-0.4	1.4	-1.0	-2.0
Worrier / anxious feelings	0.3	0.5	1.8	-1.1	-0.8	0.5	-0.2	-0.2	-1.3	0.1	0.3	-0.7
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	2.8	-1.7	1.2	-0.0	-1.1	0.8	0.0	-0.5	0.5	0.7
Falls in the last year	0.8	1.1	3.2	-0.6	1.0	-1.8	-1.0	0.5	0.9	-1.2	1.0	0.9
Hair/balding pattern: Pattern 3	2.2	3.3	8.1	2.0	-2.4	0.8	-0.7	0.9	-1.0	1.8	-2.4	-2.8
Number of live births	0.6	0.9	1.7	-1.2	1.0	0.3	-0.8	0.2	1.3	-0.0	1.3	1.3
Forced expiratory volume in 1-second (FEV1)	0.4	1.3	4.2	0.8	-0.0	-0.5	1.8	-1.4	-1.1	-0.5	-2.0	0.6
Pulse rate	0.6	1.0	3.2	-0.0	-0.4	0.4	-1.1	1.8	1.2	1.4	0.2	-0.7
Happiness	1.1	1.3	3.2	0.2	-1.3	0.4	0.5	0.5	-1.8	1.2	-1.6	-1.6
Noisy workplace	0.7	0.8	3.4	-0.2	1.1	-1.9	-0.0	-0.0	0.0	-1.4	-0.5	0.6
Qualifications: A levels/AS levels or equivalent	0.5	1.1	3.5	0.9	-0.3	-1.1	1.9	-1.6	0.0	-1.0	-0.7	0.1
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	2.0	-0.8	-0.4	1.0	0.4	0.6	-0.8	1.4	-0.1	-0.5
Mouth/teeth dental problems: Dentures	0.6	1.0	5.1	0.6	0.7	2.2	1.4	0.2	-0.9	-0.5	-0.2	0.2
Asthma	1.2	2.4	5.7	-2.0	1.3	-0.1	-2.3	2.4	1.8	-0.2	1.0	0.6
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	3.0	-1.1	0.4	-0.4	-1.7	0.3	-1.4	-0.8	-0.2	0.1
Medication: Cholesterol lowering	1.4	2.2	7.1	0.2	2.2	-1.5	0.6	-1.0	0.3	-2.7	0.6	2.1
Depression (self-reported)	0.8	1.0	3.3	-1.5	-1.0	-0.4	1.0	-0.1	-1.8	0.4	-0.8	-0.8
Medication: Lansoprazole	0.6	0.7	2.2	0.7	0.8	0.1	0.0	-1.5	-0.7	-1.1	0.9	0.7
Prospective memory result	0.3	0.4	1.3	-0.2	0.6	-0.6	-0.2	-0.9	-0.5	-1.2	-0.1	0.7
Lung cancer (father)	0.1	0.1	0.8	0.1	-0.1	0.9	0.0	-0.3	-0.1	-0.1	0.4	-0.2
Illnesses of mother	0.2	0.3	1.3	0.3	-0.2	0.1	0.7	0.3	1.2	-0.0	-0.6	-0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.2	3.5	0.5	0.0	-0.7	1.6	-1.4	-1.3	-0.2	-1.9	0.7
Pulse wave Arterial Stiffness index	1.2	1.4	3.3	0.2	-0.7	-1.4	-1.8	1.2	0.5	0.8	-1.8	-1.1
Impedance of arm (left)	0.2	0.9	4.1	-0.3	-1.0	-2.0	-0.8	0.1	1.4	-0.5	-0.3	-0.4
Arm fat mass (right)	1.3	5.2	23.2	-2.3	3.1	-0.6	-4.8	0.7	1.0	-1.0	1.3	2.0
Trunk predicted mass	0.2	1.0	2.8	0.8	1.3	1.7	0.2	-0.0	-1.7	0.0	-0.7	0.8
Standing height	0.2	2.3	6.3	2.4	-1.1	1.1	0.1	-0.3	-2.5	0.7	-2.1	-1.0
Length of working week for main job	1.8	2.0	5.0	1.4	-1.4	2.2	0.8	1.3	-0.9	1.2	-1.1	-1.8
Exposure to tobacco smoke at home	0.4	0.5	3.1	0.1	0.3	0.1	-0.3	1.8	-0.8	-0.1	-0.6	-0.4
Breastfed as a baby	1.2	1.4	3.4	0.5	1.3	-0.2	0.9	-1.2	-0.7	-1.6	1.8	1.6
Tense / ‘highly strung’	1.1	1.8	4.8	-2.2	-1.4	0.9	-1.3	1.4	-0.9	0.8	-0.0	-1.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	1.4	-0.1	-0.4	-1.2	0.7	-0.3	-0.7	-0.1	-1.1	-0.3
Hair/balding pattern: Pattern 4	0.3	0.7	1.7	-1.1	-0.1	-1.3	-0.2	-1.1	-0.5	-1.3	-0.5	0.3
Birth weight of first child	0.3	0.5	1.6	-0.2	0.1	-1.3	0.1	-0.1	-1.1	0.9	-0.7	-0.2
Peak expiratory flow (PEF)	0.4	1.0	3.3	0.8	0.9	-0.6	1.8	-1.0	0.4	-1.0	-0.8	1.1
Pulse wave reflection index	0.9	1.1	2.9	0.7	-1.2	-0.7	-0.3	-0.3	-1.7	1.0	-1.4	-1.2
Ever highly irritable/argumentative for 2 days	0.6	0.7	1.7	0.8	-0.6	0.3	0.4	1.1	0.8	1.3	-0.7	-1.1
Loud music exposure frequency	0.8	0.9	2.1	-1.4	1.4	-0.7	-1.1	0.1	0.3	-1.1	-0.0	1.0
Qualifications: O levels/GCSEs or equivalent	0.5	0.7	2.4	0.4	-0.2	-1.1	0.7	-1.5	-0.7	-0.6	-1.2	0.1
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	2.8	1.7	-0.6	-0.3	0.6	-0.4	0.0	0.1	-0.7	-0.5
Blood clot in the leg (DVT)	1.1	1.4	3.2	0.7	1.1	0.8	1.3	-1.4	-0.8	-1.8	0.7	1.5
Medication: Paracetamol	0.8	1.3	2.6	-1.6	1.2	-0.5	-0.9	-1.0	-0.7	-1.3	1.0	1.4
Headache pain in last month	0.4	0.7	2.9	-0.6	0.3	1.7	0.1	1.5	-0.6	0.2	0.7	-0.1
Medication for cholesterol, blood pressure or diabetes	1.0	1.6	4.8	0.4	-2.0	1.1	-0.2	0.7	0.6	2.2	-0.5	-1.8
Glaucoma (self-reported)	0.8	1.0	3.0	-0.9	0.4	0.7	-0.6	1.6	1.7	1.1	0.3	-0.0
Gout (self-reported)	0.5	0.6	2.3	0.3	0.5	-1.5	-1.1	-0.5	0.9	-0.8	0.0	0.3
Hypothyroidism/myxoedema (self-reported)	0.3	0.5	1.3	0.2	0.2	1.1	1.1	-0.1	-1.1	-0.7	0.3	-0.1
Medication: Amlodipine	0.4	0.5	2.1	-0.6	0.1	0.1	-1.4	0.7	-1.1	0.4	0.7	0.1
Medication: Ventolin 100micrograms inhaler	1.5	1.9	4.6	-1.4	1.1	-2.2	-1.8	-0.5	0.7	-1.4	1.3	1.3
Birth weight	0.7	1.5	4.8	2.0	-1.0	-0.7	-0.1	0.0	-0.8	1.2	-2.2	-1.2
Chronic bronchitis/emphysema (mother)	0.7	0.8	2.8	-1.2	1.2	0.3	-0.9	0.7	0.1	-0.1	1.7	0.7
High blood pressure (siblings)	1.2	1.7	4.0	-1.4	1.9	-0.4	-1.0	-0.0	0.3	-2.0	1.2	1.6
Forced vital capacity (FVC), Best measure	0.4	1.4	4.5	0.5	-0.4	-1.2	1.1	-1.7	-1.2	-0.7	-2.1	0.4
Body fat percentage	1.5	5.9	29.4	-2.7	2.6	-1.6	-5.4	0.4	1.2	-1.0	1.2	1.7
Leg fat percentage (right)	1.5	5.3	21.3	-2.8	2.8	-1.8	-4.6	-0.1	0.9	-1.2	1.4	1.9
Arm fat-free mass (right)	0.2	0.9	3.1	0.7	0.8	1.3	-0.9	-0.5	-1.8	0.4	-0.8	0.2
Exposure to tobacco smoke outside home	1.0	1.3	4.1	-0.3	1.2	0.4	0.8	2.0	2.0	0.1	-1.2	0.5
Comparative body size at age 10	0.4	1.2	5.5	-2.3	0.6	-0.3	-1.9	-0.0	0.5	1.0	0.3	0.6
Number of full brothers	0.9	1.1	5.2	2.3	-0.5	0.2	1.0	0.0	-1.5	0.8	-0.7	-0.7
Worry too long after embarrassment	0.9	1.5	6.0	-1.8	0.4	0.2	0.3	-0.8	0.0	-1.7	2.4	0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	1.4	1.8	6.0	2.1	-1.1	0.9	1.0	0.6	-2.4	1.1	-0.4	-1.2
Wheeze or whistling in the chest in last year	0.8	1.5	4.5	-1.6	1.4	-1.3	-1.1	-0.5	-0.3	-2.1	-0.2	1.1
Number of children fathered	1.3	1.5	3.7	1.4	-1.1	1.8	-0.9	0.7	-0.5	1.9	-0.1	-1.3
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	2.7	0.1	-0.2	-0.6	0.2	1.6	0.4	0.7	-0.8	-0.5
Age at first live birth	1.1	1.9	5.1	1.0	-0.2	-2.3	0.8	-2.0	1.1	-1.8	-1.1	0.7
Pulse wave peak to peak time	0.9	1.0	2.6	-0.1	0.3	1.4	1.6	-1.1	-0.9	-0.5	1.3	0.6
Health satisfaction	0.4	0.5	2.0	1.4	-0.4	0.5	0.0	0.9	-0.7	0.5	-0.1	-0.8
Shortness of breath walking on level ground	1.6	1.9	8.2	-0.9	1.1	0.5	-1.0	2.9	2.2	0.5	0.5	0.6
Qualifications: College or University degree	0.8	2.6	9.9	2.2	-0.8	0.1	3.1	-2.4	-1.3	-0.7	0.3	-0.1
Eye problems/disorders: None of the above	0.6	0.6	1.3	0.5	0.9	-1.1	-0.5	-1.1	0.2	-0.9	0.5	0.9
Mouth/teeth dental problems: Loose teeth	0.3	0.4	1.9	-0.7	-0.0	-1.4	-0.6	-0.8	0.1	-0.4	-0.0	0.1
Emphysema/chronic bronchitis	0.6	0.6	1.5	-0.9	1.2	1.0	0.0	-0.1	0.2	-0.7	0.8	1.1
Medication for pain relief, constipation, heartburn	0.5	0.8	5.1	0.5	0.1	0.6	1.0	0.5	2.3	-0.1	0.8	0.2
Neck or shoulder pain in last month	0.4	0.6	1.6	-0.8	-0.6	0.4	-0.2	0.7	-1.3	0.8	1.1	-0.6
Medication: Blood pressure	0.5	0.9	2.0	-0.8	0.9	-1.3	-0.5	-0.8	-1.1	-1.4	0.4	0.9
Angina (self-reported)	1.0	1.3	2.8	-0.4	1.7	-0.7	-1.1	0.4	1.2	-1.3	0.9	1.6
Migraine (self-reported)	0.9	1.1	2.9	0.8	-0.9	1.7	0.8	1.3	-0.2	1.2	-0.4	-1.1
Medication: Ibuprofen	0.4	0.5	1.8	-0.9	0.3	-0.3	-1.4	-0.2	-1.0	-0.5	0.4	0.2
Medication: Allopurinol	0.9	1.3	2.5	-0.9	1.3	-1.6	-1.4	-0.3	1.0	-1.1	1.1	0.9
Medication: Omeprazole	0.5	0.6	2.2	-0.6	-0.7	-0.7	-0.5	-0.9	-1.5	0.5	-0.6	-0.5
Medication: Seretide 50 evohaler	1.4	1.7	3.8	-0.5	1.9	-1.2	-1.5	-0.8	0.5	-1.6	0.9	1.7
Mean time to correctly identify matches	0.6	1.2	4.0	0.1	-0.6	2.0	-0.2	1.1	-1.6	0.6	-0.5	-1.3
Heart disease (mother)	1.7	2.1	5.3	-0.3	2.0	-1.3	0.2	-1.6	-0.1	-2.1	0.8	2.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	1.6	1.2	-1.2	-0.5	-0.3	0.2	-0.3	0.7	-0.9	-1.3
Whole body fat mass	1.2	4.8	24.8	-2.2	2.8	-0.8	-5.0	0.3	0.6	-0.9	1.1	1.8
Leg fat mass (right)	1.2	4.5	19.9	-2.2	2.9	-0.9	-4.5	0.0	0.3	-1.1	1.2	1.9
Arm predicted mass (right)	0.2	0.9	3.5	0.7	1.1	1.4	-0.7	-0.4	-1.9	0.2	-0.5	0.6
Pulse rate, automated reading	0.6	1.8	3.4	-0.2	1.7	0.5	-1.3	1.8	1.8	-0.1	1.8	1.4
Alcohol intake frequency.	0.4	0.8	3.4	0.1	-0.7	1.0	0.2	-0.4	-1.9	1.2	0.2	-0.9
Comparative height size at age 10	0.1	0.7	1.9	1.1	0.4	-0.2	-1.3	-0.8	-1.4	-0.7	-0.7	0.1
Number of full sisters	1.0	1.2	6.8	0.9	0.8	1.2	2.6	-0.2	0.1	-0.8	0.2	0.5
Suffer from ‘nerves’	0.6	1.0	2.0	-1.3	-1.3	-0.5	-0.8	-0.0	-0.7	1.4	-1.0	-1.2
Overall health rating	1.1	2.4	9.7	-0.9	0.9	-2.3	-3.1	0.1	-1.9	-1.1	-0.1	0.5
Chest pain or discomfort	1.0	1.5	4.4	0.3	2.1	-0.2	0.3	0.4	0.5	-2.0	1.2	1.7
Had major operations	1.9	2.2	6.8	2.2	0.7	1.0	2.6	-1.4	-0.9	-1.8	0.4	0.8
Age at last live birth	1.3	1.9	8.2	1.1	-1.6	-1.9	0.7	-2.9	0.2	-0.6	-1.0	-0.4
Family relationship satisfaction	0.5	0.6	2.4	0.2	-0.3	0.6	-0.6	1.6	1.2	0.6	-0.2	-0.7
Leg pain on walking	0.5	0.6	1.8	-0.2	1.1	0.0	-0.0	1.3	1.3	0.5	0.5	0.8
Qualifications: NVQ or HND or HNC or equivalent	0.8	0.9	2.4	-1.0	0.1	-1.5	-0.2	-0.8	-1.0	-0.9	-1.6	0.5
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.9	-0.4	-0.3	0.5	-1.0	0.4	-0.0	0.3	0.6	-0.1
Illness, injury, bereavement, stress in last 2 years	0.9	1.2	5.1	0.9	0.0	-2.3	-0.0	-1.2	1.5	-0.5	0.5	0.5
Medication: Aspirin	1.2	1.6	4.3	2.1	0.8	1.2	1.7	-0.4	-1.8	-1.2	-0.7	0.4
Supplements: Vitamin C	0.9	1.1	2.7	1.6	-1.1	0.8	1.3	-0.2	-0.3	0.8	-1.4	-1.0
Knee pain experienced in last month	1.1	1.7	6.7	0.5	1.0	-1.5	-2.6	-0.3	0.5	-0.3	2.0	0.8
Hypertension (Self-reported)	0.8	2.2	6.5	-1.5	1.7	-1.2	-2.6	-0.1	0.0	-1.0	1.6	1.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.7	2.0	4.6	-1.5	1.8	-1.5	0.3	-1.3	0.1	-1.5	1.1	2.1
Illnesses of father: Heart disease	2.8	3.9	10.8	0.3	3.3	-0.1	0.8	1.2	2.6	-1.6	2.2	2.8
Illnesses of siblings: Diabetes	0.4	0.5	0.9	0.5	0.9	-0.8	0.9	0.7	-0.5	-0.9	-0.5	0.6
Smoking status: Previous	0.5	0.7	1.8	0.5	-0.1	-1.2	0.0	1.3	1.1	0.3	-1.0	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	2.1	4.4	14.7	0.5	-2.4	0.3	-0.2	1.1	-2.4	2.5	-3.8	-2.4
Whole body fat-free mass	0.2	1.1	3.3	0.6	1.8	1.5	-0.7	0.0	-1.4	-0.4	-0.2	1.2
Leg fat-free mass (right)	0.2	1.3	4.0	0.8	2.0	1.4	-1.6	0.4	-0.7	-0.6	0.2	1.3
Arm fat percentage (left)	1.8	7.1	28.4	-3.2	3.2	-1.3	-5.3	0.6	1.9	-1.4	1.7	2.2
Average weekly red wine intake	0.7	1.0	2.5	1.3	-0.6	1.6	1.3	0.8	1.2	0.6	0.2	-0.5
Handedness (chirality/laterality): Left-handed	3.8	4.6	11.2	0.3	-3.3	0.1	-0.1	0.7	-1.8	3.1	-2.4	-3.4
Mood swings	0.4	0.8	2.7	-0.1	-0.7	-0.7	0.5	0.1	-1.7	0.6	-1.2	-0.9
Loneliness, isolation	0.4	0.6	2.4	0.5	0.0	1.1	1.5	-0.3	-1.1	0.1	0.2	-0.0
Long-standing illness, disability or infirmity	1.2	1.8	6.2	-1.5	1.5	-1.0	-2.5	0.3	-1.2	-0.7	1.2	0.9
Ever had bowel cancer screening	1.2	1.4	3.1	-0.4	1.7	-0.4	0.1	-0.8	-0.1	-1.8	1.7	1.7
Diabetes diagnosed by doctor	1.6	2.6	6.1	-2.2	2.2	0.6	-0.7	0.0	-1.0	-2.5	1.6	1.8
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.7	2.5	-0.7	-0.8	-0.1	-0.8	1.6	0.9	0.7	-0.7	-0.7
Friendships satisfaction	0.4	0.5	1.2	-1.0	1.1	-0.5	-0.4	-0.2	0.4	-0.3	0.8	1.0
Qualifications: nursing, teaching	0.4	0.7	3.2	0.9	-0.4	0.9	1.8	-0.1	-0.3	0.7	0.2	-0.6
Commuting to job workplace: Walk	0.6	0.7	3.3	-1.8	-0.1	-1.0	-0.8	-0.2	0.4	-0.4	-0.8	0.1
Eye problems/disorders: Cataract	0.4	0.5	2.2	-0.0	-0.4	-0.6	-1.5	0.7	0.8	0.2	-0.1	-0.4
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	2.2	-1.2	0.4	-1.5	-0.5	-0.7	0.3	-0.3	-0.3	0.4
Medication for cholesterol	0.7	1.0	4.7	0.5	-0.7	-0.8	2.2	-1.3	0.2	-0.4	-1.2	-0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.5	1.8	6.2	-0.9	-1.2	-0.9	-2.0	-0.6	-2.5	1.1	-0.8	-0.8
Back pain experienced in last month	1.3	1.9	6.2	-1.2	1.8	-0.9	-2.5	1.3	0.2	-0.3	1.5	1.2
Mineral and other dietary supplements	1.4	1.9	4.4	-2.1	1.0	-1.2	-1.8	0.3	1.2	-0.3	1.9	1.4
Breast cancer (self-reported)	0.5	0.6	1.5	-0.8	0.5	0.4	0.7	-1.2	-0.7	-1.1	0.2	0.8
Asthma (self-reported)	0.9	1.9	5.1	-1.5	1.2	-0.0	-1.9	2.2	1.8	-0.1	1.1	0.5
Osteoporosis (self-reported)	0.9	1.1	5.0	0.6	-0.8	-0.6	-0.6	-0.5	-1.6	-0.1	-2.2	-0.4
Osteoarthritis (self-reported)	0.2	0.2	1.1	-0.3	0.2	-0.5	-1.1	-0.3	-0.4	0.1	0.2	0.0
Medication: Aspirin	1.4	1.8	5.9	2.4	0.7	1.0	2.0	-0.5	-1.4	-1.2	-0.8	0.5
Medication: Gliclazide	2.8	3.2	8.8	-0.2	3.0	-0.7	-0.9	0.2	1.1	-2.5	2.0	2.6
Illnesses of father: None of the above (group 1)	0.7	0.9	2.5	0.0	-1.6	-0.8	-0.1	-0.7	-1.4	0.6	-0.8	-1.3
Smoking status: Current	0.4	0.7	1.6	1.3	-1.1	0.5	-0.2	0.3	-1.1	0.5	-0.1	-1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	2.3	-0.4	0.6	-1.5	0.3	-0.8	0.1	-0.9	0.2	0.9
Whole body water mass	0.2	1.1	3.1	0.6	1.8	1.4	-0.6	-0.1	-1.4	-0.4	-0.3	1.2
Leg predicted mass (right)	0.2	1.3	4.0	0.9	2.0	1.4	-1.5	0.3	-0.8	-0.6	0.2	1.3
Arm fat mass (left)	1.2	4.9	21.2	-2.4	3.0	-0.4	-4.6	0.6	0.9	-1.0	1.2	2.0
Number of self-reported non-cancer illnesses	1.4	2.4	4.8	-1.1	1.9	-1.3	-0.7	-0.9	-1.5	-2.2	1.9	1.9
Average weekly champagne plus white wine intake	0.8	1.1	2.5	0.1	0.7	-1.2	0.3	-1.6	-0.5	-1.1	1.2	1.5
Miserableness	0.3	0.5	1.9	-0.0	0.7	-0.3	1.4	-0.2	-1.0	-0.9	-0.3	0.4
Guilty feelings	0.8	1.3	3.1	0.2	-1.6	1.8	1.2	0.5	-0.7	1.1	-0.4	-1.4
Wears glasses or contact lenses	0.9	1.0	3.3	-1.8	1.1	-0.6	-1.1	0.7	0.4	-0.6	1.0	0.8
Ever taken oral contraceptive pill	2.5	2.7	7.3	-0.2	1.7	0.3	1.6	-1.5	1.2	-2.7	1.7	2.3
Hearing aid user	0.8	0.9	2.9	-0.7	1.3	1.7	0.6	0.4	0.6	-0.4	1.4	0.8
Mother’s age at death	1.4	1.8	6.0	1.4	-0.3	1.8	0.2	2.5	1.7	0.4	0.4	-1.1
Financial situation satisfaction	0.5	0.6	2.0	-0.0	1.4	-0.1	0.0	-0.4	0.2	-1.0	-0.8	1.1
Tinnitus: Yes, now most or all of the time	0.4	0.5	1.3	-0.2	1.2	0.7	0.2	1.0	-0.1	-0.7	-0.3	0.9
Commuting to job workplace: Public transport	0.1	0.1	0.7	0.2	0.1	-0.2	0.8	-0.1	0.6	-0.3	-0.0	0.1
Eye problems/disorders: Glaucoma	0.3	0.4	1.9	-0.3	-0.0	1.4	0.9	0.4	0.4	0.5	0.3	-0.1
Medication: Blood pressure	0.4	0.7	2.6	-0.9	0.7	0.3	-1.6	0.9	-0.5	-0.1	0.9	0.5
Pain type(s) experienced in last month: Hip pain	1.7	2.2	6.4	-2.5	0.7	0.8	-1.8	2.1	1.6	1.1	0.9	-0.0
Supplements: Fish oil (including cod liver oil)	1.0	1.3	3.8	1.4	-0.5	1.9	1.6	0.6	-0.6	0.6	-0.9	-1.3
High cholesterol (Self-reported)	0.3	0.5	2.3	0.5	0.4	-0.3	-0.9	-0.0	-1.5	-0.3	0.7	0.4
Medication: Bendroflumethiazide	0.6	0.8	3.1	0.1	-0.3	0.0	-1.3	0.6	-1.8	0.6	-1.2	-0.7
Medication: Paracetamol	1.2	1.8	5.1	-0.9	1.9	-0.6	-0.4	-1.2	-0.1	-1.7	1.5	2.2
Medication: Lisinopril	0.8	1.1	3.0	-1.2	0.9	-1.7	-1.6	0.2	0.5	-0.9	-0.3	0.7
Medication: Atorvastatin	0.7	0.8	2.4	0.2	0.4	-0.7	-1.5	1.2	1.4	0.2	0.9	0.3
Illnesses of father: High blood pressure	0.7	0.9	3.0	-1.5	0.8	-0.5	-1.7	0.7	0.8	-0.4	0.2	0.7
Alcohol drinker status: Never	2.0	2.4	5.7	1.5	-1.6	2.4	1.3	0.9	-0.8	1.8	-1.2	-1.8
Ever smoked	0.6	1.0	4.9	2.2	-1.0	-0.4	0.8	0.5	-0.2	0.3	-0.8	-1.2
Basal metabolic rate	0.2	1.2	4.5	0.2	2.1	1.1	-1.4	0.0	-1.1	-0.5	-0.1	1.4
Leg fat percentage (left)	1.3	4.9	21.6	-2.4	2.6	-1.8	-4.7	0.1	1.1	-0.8	1.2	1.8
Arm fat-free mass (left)	0.2	1.1	3.4	0.7	1.8	1.5	-0.9	0.1	-1.3	-0.2	-0.2	1.1
Number of operations (self-reported)	1.6	2.3	4.4	1.5	1.6	0.9	1.5	-1.0	0.5	-2.0	2.1	2.0
Average weekly beer plus cider intake	0.6	0.9	2.8	-0.2	-0.8	0.9	-0.1	0.6	-1.7	-0.1	-1.3	-1.2
Irritability	0.6	1.1	2.7	-0.7	-0.7	-0.4	-1.0	1.5	-0.2	1.6	-1.2	-1.1
Risk taking	2.2	3.2	7.0	1.9	-2.5	0.4	-0.8	0.9	-0.3	1.9	-2.5	-2.6
Ever had prostate specific antigen (PSA) test	1.4	1.7	5.7	-1.1	0.6	-1.2	-0.2	-2.4	-0.0	-2.1	0.7	1.1
Fractured/broken bones in last 5 years	0.8	1.1	3.5	1.1	-1.0	-0.8	0.0	-1.5	-1.9	-0.5	-0.8	-0.2
Age started oral contraceptive pill	0.5	0.6	2.9	0.2	0.6	-0.1	0.4	-0.8	1.7	-0.4	1.0	0.6
Diastolic blood pressure, automated reading	2.1	6.6	14.3	-3.2	3.1	-3.8	-2.4	-1.4	1.4	-2.0	0.9	3.3
Ever depressed for a whole week	1.7	2.1	4.8	0.5	-1.7	1.2	-0.5	1.6	-1.5	1.8	-0.9	-2.2
Unable to work because of sickness or disability	0.3	0.4	1.1	-0.4	1.1	-0.3	-1.0	0.4	-0.1	-0.2	0.2	0.7
Commuting to job workplace: Cycle	0.5	0.6	2.6	-0.8	0.1	-0.9	-0.0	-1.6	0.6	-0.5	0.6	0.5
Myopia	0.5	0.7	2.5	-1.6	0.2	-1.4	-0.0	0.6	1.0	0.1	0.7	0.0
Vascular/heart problems diagnosed by doctor	0.9	2.5	6.8	1.5	-2.0	1.4	2.6	-0.1	-0.4	1.4	-1.4	-2.0
Cholesterol lowering medication	0.5	0.8	2.2	0.5	0.1	1.1	-1.5	0.6	-1.3	0.7	0.7	-0.1
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	1.2	-0.5	-0.9	-0.4	-0.2	-0.9	-1.1	0.8	-0.4	-0.7
Pain experienced in last month	0.4	0.6	2.9	-0.6	-0.1	0.5	1.7	-0.6	1.2	-0.3	-0.2	0.3
Supplements: Calcium	1.3	1.4	4.3	0.2	1.4	0.4	1.8	-1.0	-0.8	-2.1	0.2	1.1
Basal cell carcinoma (self-reported)	0.6	0.7	2.4	-1.1	-0.4	-0.5	-0.9	-1.6	-0.6	-0.6	-0.5	0.4
Heart attack/myocardial infarction (self-reported)	0.8	1.1	2.9	0.5	1.4	-0.1	0.6	-0.5	0.2	-1.6	1.7	1.2
Deep venous thrombosis (DVT) (self-reported)	1.1	1.4	3.6	0.3	1.3	0.8	1.1	-1.4	-0.6	-1.9	0.6	1.6
Heart disease (siblings)	0.3	0.3	0.9	0.5	-0.0	0.7	0.1	0.8	0.9	0.2	0.7	-0.3
Alcohol drinker status: Previous	1.6	1.8	5.6	1.7	-1.4	0.4	1.3	-0.9	-2.4	1.1	-0.5	-1.4
Pack years of smoking	0.5	0.8	1.7	0.6	-1.1	0.5	-1.3	-0.3	-0.7	1.1	0.0	-1.3
Impedance of whole body	0.3	1.4	4.9	0.0	-2.0	-2.2	-0.4	-0.2	0.4	0.4	-1.1	-1.3
Leg fat mass (left)	1.2	4.6	22.0	-2.2	2.8	-1.1	-4.7	-0.0	0.4	-1.0	1.1	1.9
Arm predicted mass (left)	0.2	1.0	3.0	1.1	1.4	1.3	-0.6	-0.2	-1.7	0.0	-0.7	0.7