[Hub]/) : Traits : Trunk fat percentage :

chr11:65,151,449-68,077,666

Best TWAS P=4.22e-11 · Best GWAS P=4.29e-13 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PTPRCAP 0.05 0.07 enet 12 0.07 6.0e-09 -5.2 5.3 9.2e-08 -0.29 0.14 0.86 FALSE
2 GTEx Adipose Subcutaneous RAD9A 0.43 0.22 lasso 6 0.23 7.1e-19 -5.6 -5.5 3.3e-08 0.18 0.03 0.97 FALSE
3 GTEx Adipose Subcutaneous AP003419.16 0.05 0.08 lasso 1 0.07 1.7e-06 -5.3 5.3 1.1e-07 -0.28 0.09 0.90 FALSE
4 GTEx Adipose Visceral Omentum GSTP1 0.11 0.12 lasso 7 0.10 6.7e-06 -5.6 5.2 1.7e-07 -0.21 0.04 0.96 FALSE
5 GTEx Adipose Visceral Omentum RPS6KB2 0.08 0.03 lasso 8 0.04 2.9e-03 -5.3 5.8 8.9e-09 -0.26 0.03 0.94 FALSE
6 GTEx Adipose Visceral Omentum PTPRCAP 0.10 0.08 enet 7 0.06 4.8e-04 -5.3 5.4 5.4e-08 -0.30 0.11 0.84 FALSE
7 GTEx Adipose Visceral Omentum AP003419.16 0.09 0.05 enet 8 0.04 4.6e-03 -5.3 5.6 2.4e-08 -0.28 0.02 0.94 FALSE
8 GTEx Artery Aorta GSTP1 0.10 0.07 enet 14 0.10 5.4e-06 -5.7 5.6 2.5e-08 -0.21 0.05 0.93 FALSE
9 GTEx Artery Aorta PTPRCAP 0.11 0.07 enet 9 0.08 3.6e-05 -5.3 5.2 2.1e-07 -0.28 0.04 0.94 FALSE
10 GTEx Artery Aorta AP003419.16 0.16 0.10 lasso 3 0.10 4.5e-06 -5.3 5.3 1.1e-07 -0.28 0.11 0.87 FALSE
11 GTEx Artery Tibial GSTP1 0.09 0.07 enet 8 0.11 7.4e-09 -5.6 5.2 1.7e-07 -0.20 0.04 0.96 FALSE
12 GTEx Artery Tibial RAD9A 0.39 0.26 lasso 2 0.24 3.5e-19 -5.6 -5.6 2.6e-08 0.18 0.03 0.97 FALSE
13 GTEx Artery Tibial RPS6KB2 0.10 0.10 lasso 1 0.10 5.9e-08 -5.3 5.3 8.8e-08 -0.28 0.08 0.92 FALSE
14 GTEx Artery Tibial PTPRCAP 0.18 0.25 lasso 7 0.24 5.9e-19 -5.2 5.2 1.5e-07 -0.28 0.18 0.82 FALSE
15 GTEx Artery Tibial AP003419.16 0.11 0.13 lasso 2 0.12 2.2e-09 -5.3 5.4 7.7e-08 -0.28 0.09 0.91 FALSE
16 GTEx Brain Caudate basal ganglia GSTP1 0.16 0.14 lasso 3 0.16 2.8e-05 4.6 5.3 8.6e-08 -0.24 0.02 0.90 FALSE
17 GTEx Brain Caudate basal ganglia PTPRCAP 0.23 0.19 lasso 4 0.21 1.0e-06 -5.3 5.5 3.1e-08 -0.28 0.03 0.96 FALSE
18 GTEx Brain Cerebellar Hemisphere GSTP1 0.25 0.15 enet 16 0.20 8.7e-06 -4.7 6.0 1.5e-09 -0.23 0.07 0.92 FALSE
19 GTEx Brain Cerebellar Hemisphere PTPRCAP 0.39 0.43 lasso 8 0.47 7.7e-14 -5.5 5.5 3.1e-08 -0.28 0.03 0.97 FALSE
20 GTEx Brain Cerebellar Hemisphere AP003419.16 0.20 0.01 lasso 4 0.05 1.7e-02 -5.4 5.6 2.6e-08 -0.21 0.03 0.44 FALSE
21 GTEx Brain Cerebellum NDUFV1 0.19 0.01 enet 29 0.05 1.7e-02 4.5 -5.8 6.7e-09 0.20 0.05 0.33 FALSE
22 GTEx Brain Cerebellum PTPRCAP 0.39 0.48 lasso 7 0.46 3.8e-15 -5.3 5.5 5.0e-08 -0.29 0.03 0.97 FALSE
23 GTEx Brain Frontal Cortex BA9 GSTP1 0.28 0.19 lasso 5 0.16 3.8e-05 -5.6 5.4 7.9e-08 -0.20 0.04 0.92 TRUE
24 GTEx Brain Frontal Cortex BA9 PTPRCAP 0.21 0.11 enet 15 0.15 9.6e-05 -5.3 5.7 1.4e-08 -0.29 0.03 0.95 FALSE
25 GTEx Brain Hippocampus PTPRCAP 0.16 0.13 lasso 4 0.18 6.2e-05 -5.5 5.5 3.7e-08 -0.26 0.02 0.86 FALSE
26 GTEx Brain Hypothalamus GSTP1 0.29 0.28 lasso 3 0.26 9.3e-07 -5.7 5.7 1.4e-08 -0.20 0.03 0.94 FALSE
27 GTEx Brain Hypothalamus PTPRCAP 0.17 0.21 lasso 4 0.19 3.1e-05 -5.3 5.5 5.0e-08 -0.29 0.04 0.89 FALSE
28 GTEx Brain Nucleus accumbens basal ganglia GSTP1 0.23 0.11 lasso 5 0.14 1.8e-04 -5.6 5.8 8.4e-09 -0.23 0.03 0.94 FALSE
29 GTEx Brain Nucleus accumbens basal ganglia PTPRCAP 0.35 0.36 lasso 7 0.38 2.7e-11 -5.3 5.3 9.9e-08 -0.29 0.10 0.90 FALSE
30 GTEx Brain Putamen basal ganglia PTPRCAP 0.24 0.26 lasso 4 0.22 6.2e-06 -5.3 5.3 1.1e-07 -0.28 0.06 0.90 FALSE
31 GTEx Breast Mammary Tissue GSTP1 0.23 0.14 lasso 5 0.13 4.7e-07 -5.4 5.1 3.1e-07 -0.20 0.05 0.95 FALSE
32 GTEx Breast Mammary Tissue PTPRCAP 0.18 0.26 lasso 3 0.24 2.0e-12 -5.3 5.4 7.6e-08 -0.28 0.16 0.84 FALSE
33 GTEx Breast Mammary Tissue AP003419.16 0.19 0.06 lasso 5 0.05 2.3e-03 -5.4 5.4 7.8e-08 -0.30 0.04 0.77 FALSE
34 GTEx Breast Mammary Tissue (Male) GSTP1 0.11 -0.01 lasso 2 -0.01 7.7e-01 -5.0 6.1 1.3e-09 -0.21 0.02 0.23 FALSE
35 GTEx Breast Mammary Tissue (Male) NDUFV1 0.11 0.05 enet 8 0.03 5.6e-02 4.6 -5.5 5.0e-08 0.26 0.05 0.35 FALSE
36 GTEx Breast Mammary Tissue (Female) GSTP1 0.26 0.10 lasso 1 0.09 1.2e-03 -5.4 5.4 8.1e-08 -0.20 0.04 0.53 FALSE
37 GTEx Cells Transformed fibroblasts RPS6KB2 0.19 0.28 lasso 3 0.27 1.7e-20 -5.3 5.4 6.3e-08 -0.28 0.12 0.88 FALSE
38 GTEx Cells Transformed fibroblasts AP003419.16 0.21 0.22 lasso 6 0.21 1.6e-15 -5.3 5.6 2.6e-08 -0.28 0.11 0.89 FALSE
39 GTEx Colon Sigmoid GSTP1 0.19 0.21 enet 11 0.19 2.7e-07 -5.6 5.3 8.6e-08 -0.18 0.04 0.96 FALSE
40 GTEx Colon Transverse PTPRCAP 0.14 0.06 lasso 7 0.07 3.8e-04 -5.3 5.2 2.4e-07 -0.28 0.07 0.90 FALSE
41 GTEx Esophagus Gastroesophageal Junction AP003419.16 0.25 0.18 lasso 16 0.18 6.7e-07 -5.3 5.2 2.3e-07 -0.28 0.12 0.87 FALSE
42 GTEx Esophagus Mucosa RPS6KB2 0.12 0.09 lasso 3 0.11 1.1e-07 -5.3 5.6 2.6e-08 -0.27 0.04 0.96 FALSE
43 GTEx Esophagus Mucosa AP003419.16 0.18 0.15 lasso 3 0.18 7.8e-12 -5.3 5.5 2.8e-08 -0.28 0.06 0.94 FALSE
44 GTEx Esophagus Muscularis GSTP1 0.16 0.18 lasso 3 0.16 9.1e-10 -5.4 5.5 2.9e-08 -0.20 0.08 0.92 FALSE
45 GTEx Esophagus Muscularis RAD9A 0.25 0.26 lasso 2 0.26 6.2e-16 -5.6 -5.2 1.9e-07 0.15 0.03 0.97 FALSE
46 GTEx Esophagus Muscularis PTPRCAP 0.21 0.26 lasso 4 0.26 9.2e-16 -5.2 5.3 1.3e-07 -0.28 0.17 0.83 FALSE
47 GTEx Esophagus Muscularis CTD-3074O7.5 0.22 0.02 enet 17 0.09 3.7e-06 -2.0 5.8 6.0e-09 -0.50 0.25 0.55 TRUE
48 GTEx Esophagus Muscularis AP003419.16 0.19 0.17 lasso 3 0.18 7.3e-11 -5.3 5.3 1.1e-07 -0.28 0.11 0.89 FALSE
49 GTEx Heart Atrial Appendage RPS6KB2 0.16 0.09 lasso 9 0.07 3.5e-04 -5.3 5.6 2.7e-08 -0.28 0.06 0.89 FALSE
50 GTEx Heart Atrial Appendage PTPRCAP 0.14 0.11 lasso 10 0.09 5.1e-05 -5.3 6.3 3.9e-10 -0.29 0.06 0.90 FALSE
51 GTEx Heart Atrial Appendage AP003419.16 0.11 0.10 lasso 5 0.12 4.4e-06 -5.3 5.3 1.4e-07 -0.28 0.06 0.93 FALSE
52 GTEx Heart Left Ventricle RPS6KB2 0.14 0.14 lasso 4 0.15 2.6e-08 -5.3 5.3 1.1e-07 -0.28 0.14 0.86 FALSE
53 GTEx Heart Left Ventricle AP003419.16 0.19 0.16 lasso 5 0.16 6.8e-09 -5.3 5.3 1.5e-07 -0.28 0.12 0.88 FALSE
54 GTEx Liver CDK2AP2 0.30 -0.01 lasso 7 -0.01 4.9e-01 -3.8 -5.5 3.1e-08 0.25 0.03 0.38 FALSE
55 GTEx Muscle Skeletal GSTP1 0.07 0.08 lasso 9 0.07 1.0e-07 -5.4 5.5 3.9e-08 -0.23 0.10 0.90 FALSE
56 GTEx Muscle Skeletal RPS6KB2 0.17 0.20 lasso 3 0.20 8.3e-19 -5.3 5.3 1.2e-07 -0.28 0.12 0.88 FALSE
57 GTEx Muscle Skeletal PTPRCAP 0.09 0.08 lasso 6 0.09 2.6e-09 -5.3 5.4 6.8e-08 -0.27 0.17 0.83 FALSE
58 GTEx Muscle Skeletal AP003419.16 0.19 0.21 lasso 2 0.20 1.4e-19 -5.3 5.4 8.4e-08 -0.28 0.12 0.88 FALSE
59 GTEx Nerve Tibial RAD9A 0.53 0.24 lasso 10 0.23 5.6e-16 -5.6 -5.7 1.2e-08 0.18 0.03 0.97 FALSE
60 GTEx Nerve Tibial PTPRCAP 0.33 0.38 enet 14 0.47 2.1e-37 -5.2 5.3 8.7e-08 -0.28 0.18 0.82 FALSE
61 GTEx Ovary PTPRCAP 0.35 0.28 enet 13 0.26 5.3e-07 -5.3 5.4 5.6e-08 -0.29 0.07 0.91 FALSE
62 GTEx Pancreas AP003419.16 0.11 0.05 enet 14 0.07 8.4e-04 -5.3 5.6 2.1e-08 -0.29 0.08 0.86 FALSE
63 GTEx Pituitary PTPRCAP 0.24 0.33 lasso 6 0.26 4.0e-07 -5.3 5.4 5.6e-08 -0.29 0.04 0.95 FALSE
64 GTEx Skin Not Sun Exposed Suprapubic RPS6KB2 0.11 0.00 lasso 6 0.00 2.3e-01 -4.8 5.2 2.0e-07 -0.16 0.02 0.42 FALSE
65 GTEx Skin Not Sun Exposed Suprapubic PTPRCAP 0.22 0.14 enet 19 0.15 1.8e-08 -5.2 5.7 1.6e-08 -0.28 0.06 0.94 FALSE
66 GTEx Skin Not Sun Exposed Suprapubic AP003419.16 0.15 0.08 lasso 5 0.08 6.2e-05 -5.5 6.0 2.0e-09 -0.27 0.02 0.96 FALSE
67 GTEx Skin Sun Exposed Lower leg AP003419.16 0.14 0.14 lasso 6 0.13 9.4e-11 -5.3 5.3 1.4e-07 -0.29 0.09 0.91 FALSE
68 GTEx Stomach AP003419.16 0.12 0.11 lasso 4 0.08 1.4e-04 -5.3 5.3 9.9e-08 -0.29 0.04 0.89 FALSE
69 GTEx Testis GSTP1 0.09 0.11 lasso 2 0.08 3.1e-04 -5.4 5.4 8.0e-08 -0.20 0.05 0.91 FALSE
70 GTEx Testis AIP 0.11 0.14 lasso 2 0.11 1.5e-05 -5.3 5.5 4.8e-08 -0.27 0.08 0.90 FALSE
71 GTEx Testis RAD9A 0.72 0.50 lasso 4 0.49 1.1e-24 -5.6 -5.6 2.4e-08 0.18 0.03 0.97 FALSE
72 GTEx Testis RPS6KB2 0.20 0.16 lasso 11 0.16 8.3e-08 -5.3 5.5 3.5e-08 -0.29 0.04 0.96 FALSE
73 GTEx Testis AP003419.16 0.22 0.18 lasso 8 0.18 1.3e-08 -5.3 5.4 6.8e-08 -0.29 0.07 0.93 FALSE
74 GTEx Thyroid PTPRCAP 0.17 0.19 lasso 4 0.21 1.1e-15 -5.2 5.3 1.3e-07 -0.28 0.18 0.82 FALSE
75 GTEx Uterus PACS1 0.21 -0.01 enet 21 0.05 3.6e-02 3.5 -5.3 1.3e-07 0.38 0.07 0.26 TRUE
76 GTEx Uterus PTPRCAP 0.28 0.15 lasso 5 0.15 5.5e-04 -5.4 5.7 1.2e-08 -0.29 0.02 0.83 FALSE
77 GTEx Vagina PTPRCAP 0.33 0.05 enet 8 0.06 2.0e-02 -5.3 5.7 1.1e-08 -0.29 0.02 0.80 FALSE
78 METSIM Adipose GSTP1 0.05 0.05 lasso 6 0.04 9.3e-07 -5.7 5.7 9.5e-09 -0.22 0.03 0.97 FALSE
79 METSIM Adipose PTPRCAP 0.03 0.02 lasso 4 0.02 1.7e-04 -5.4 5.6 2.2e-08 -0.29 0.07 0.91 FALSE
80 ROSMAP Brain Pre-frontal Cortex GSTP1 0.25 0.38 lasso 7 0.42 6.1e-58 -5.6 5.4 7.7e-08 -0.21 0.04 0.96 TRUE
81 ROSMAP Brain Pre-frontal Cortex CDK2AP2 0.03 0.02 enet 11 0.03 1.6e-04 -4.9 6.6 4.2e-11 -0.22 0.06 0.91 TRUE
82 ROSMAP Brain Pre-frontal Cortex RPS6KB2 0.24 0.37 lasso 5 0.37 7.2e-50 -5.2 5.2 1.9e-07 -0.28 0.17 0.82 FALSE
83 ROSMAP Brain Pre-frontal Cortex PTPRCAP 0.31 0.47 enet 14 0.47 2.7e-68 -5.3 5.3 1.1e-07 -0.28 0.17 0.83 FALSE
84 YFS Blood RPS6KB2 0.04 0.05 lasso 7 0.05 6.7e-17 -5.2 5.2 1.8e-07 -0.28 0.17 0.83 FALSE
85 The Cancer Genome Atlas Breast Invasive Carcinoma RPS6KB2 0.05 0.06 lasso 3 0.06 1.1e-12 -5.5 5.5 4.2e-08 -0.29 0.01 0.99 FALSE
86 The Cancer Genome Atlas Colon Adenocarcinoma RPS6KB2 0.11 0.12 lasso 6 0.10 1.2e-06 -5.3 5.3 1.2e-07 -0.28 0.02 0.98 FALSE
87 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CNIH2 0.03 0.00 enet 4 0.02 6.4e-03 -4.6 5.2 1.8e-07 -0.58 0.06 0.12 FALSE
88 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma RPS6KB2 0.09 0.16 enet 9 0.15 2.1e-16 -5.3 5.3 1.3e-07 -0.28 0.02 0.98 FALSE
89 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma GSTP1 0.04 0.05 lasso 5 0.04 1.7e-03 -5.6 5.7 1.3e-08 -0.19 0.01 0.94 FALSE
90 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma PTPRCAP 0.05 0.04 enet 3 0.03 1.2e-02 -5.4 5.7 1.2e-08 -0.27 0.01 0.78 FALSE
91 The Cancer Genome Atlas Brain Lower Grade Glioma GSTP1 0.11 0.08 enet 5 0.07 7.2e-09 -5.6 5.5 4.2e-08 -0.20 0.01 0.99 FALSE
92 The Cancer Genome Atlas Lung Adenocarcinoma RPS6KB2 0.05 0.07 lasso 4 0.06 6.2e-08 -5.5 5.6 2.5e-08 -0.29 0.01 0.99 FALSE
93 The Cancer Genome Atlas Lung Squamous Cell Carcinoma RPS6KB2 0.05 0.05 lasso 6 0.04 1.2e-05 -5.3 5.4 7.7e-08 -0.28 0.02 0.98 FALSE
94 The Cancer Genome Atlas Prostate Adenocarcinoma PTPRCAP 0.08 0.10 lasso 2 0.10 7.8e-11 -5.2 5.2 1.5e-07 -0.28 0.02 0.98 FALSE
95 The Cancer Genome Atlas Prostate Adenocarcinoma RPS6KB2 0.09 0.13 lasso 6 0.13 7.1e-14 -5.3 5.4 6.6e-08 -0.26 0.01 0.98 FALSE
96 The Cancer Genome Atlas Soft Tissue Sarcoma RPS6KB2 0.05 0.04 lasso 2 0.04 2.1e-03 -5.3 5.3 1.1e-07 -0.28 0.01 0.94 FALSE
97 The Cancer Genome Atlas Stomach Adenocarcinoma RPS6KB2 0.10 0.11 lasso 4 0.10 8.6e-08 -5.3 5.3 1.3e-07 -0.28 0.02 0.98 TRUE
98 The Cancer Genome Atlas Testicular Germ Cell Tumors RPS6KB2 0.12 0.06 blup 35 0.05 5.4e-03 -5.5 6.1 1.4e-09 -0.28 0.01 0.81 FALSE
99 The Cancer Genome Atlas Testicular Germ Cell Tumors TBC1D10C 0.12 0.05 lasso 5 0.03 3.0e-02 -5.3 5.3 1.2e-07 -0.28 0.01 0.80 FALSE
100 The Cancer Genome Atlas Thyroid Carcinoma NDUFV1 0.03 0.00 blup 43 0.01 6.7e-02 -4.9 -5.4 7.7e-08 0.21 0.01 0.89 FALSE