[Hub]/) : Traits : Trunk fat-free mass :

chr11:8,017,744-11,227,175

Best TWAS P=1.46e-16 · Best GWAS P=4e-17 conditioned to 0.833

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum TMEM9B 0.12 0.03 enet 18 0.06 2.8e-04 6.82 5.2 1.9e-07 -0.15 0.01 0.85 FALSE
2 GTEx Brain Cortex ZNF143 0.27 0.13 lasso 5 0.10 7.8e-04 -6.25 -5.2 2.3e-07 0.15 0.04 0.72 FALSE
3 GTEx Brain Cortex RP11-152H18.3 0.41 0.04 enet 25 0.11 7.6e-04 3.93 -6.0 1.7e-09 0.03 0.05 0.61 TRUE
4 GTEx Cells Transformed fibroblasts AMPD3 0.20 0.02 lasso 8 0.01 5.5e-02 -5.01 5.2 1.6e-07 -0.22 0.30 0.03 FALSE
5 GTEx Prostate SBF2 0.21 0.05 lasso 7 0.03 6.7e-02 7.75 8.1 7.1e-16 -0.86 0.04 0.77 FALSE
6 GTEx Testis SBF2 0.10 0.01 lasso 5 0.02 5.0e-02 7.26 -7.7 1.0e-14 0.82 0.07 0.82 FALSE
7 METSIM Adipose AMPD3 0.06 0.03 enet 14 0.05 7.8e-08 4.09 5.2 2.6e-07 -0.08 0.96 0.00 TRUE
8 NTR Blood ADM 0.04 0.04 enet 13 0.04 1.6e-13 7.72 -8.3 1.5e-16 0.88 0.09 0.91 TRUE
9 NTR Blood WEE1 0.02 0.00 bslmm 367 0.00 1.0e-02 0.36 -6.2 5.7e-10 0.33 0.10 0.20 FALSE
10 ROSMAP Brain Pre-frontal Cortex SBF2-AS1 0.03 0.00 bslmm 362 0.01 4.4e-03 -1.73 7.2 5.8e-13 -0.59 0.04 0.63 FALSE
11 YFS Blood ADM 0.08 0.11 enet 25 0.12 9.4e-36 7.92 -7.9 2.3e-15 0.85 0.10 0.90 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma ZNF143 0.02 0.02 lasso 2 0.02 4.5e-03 6.55 -6.7 2.3e-11 0.07 0.01 0.94 TRUE