TWAS hub - TMEM9B

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1620	0.0480	3.1e-06	0.045	NA	0.057	NA	0.070	1.4e-04	NA	1.9e-05	NA	2.4e-06
2	GTEx	Adipose Visceral Omentum	0.1230	0.0570	9.5e-03	0.026	NA	0.065	NA	0.024	1.6e-02	NA	2.8e-04	NA	2.1e-02
3	GTEx	Breast Mammary Tissue	0.1660	0.0670	8.9e-04	-0.003	NA	0.051	NA	0.016	5.3e-01	NA	1.2e-03	NA	4.6e-02
4	GTEx	Breast Mammary Tissue (Male)	0.1698	0.1139	7.4e-02	-0.005	NA	0.052	NA	0.008	4.4e-01	NA	2.4e-02	NA	2.0e-01
5	GTEx	Cells EBV-transformed lymphocytes	0.2370	0.0730	2.1e-05	0.142	NA	0.129	NA	0.138	2.4e-05	NA	5.5e-05	NA	3.0e-05
6	GTEx	Cells Transformed fibroblasts	0.1280	0.0510	2.7e-04	0.044	NA	0.060	NA	0.039	2.9e-04	NA	2.7e-05	NA	6.2e-04
7	GTEx	Esophagus Mucosa	0.2230	0.0670	7.1e-09	0.112	NA	0.094	NA	0.155	6.1e-08	NA	8.1e-07	NA	1.6e-10
8	GTEx	Esophagus Muscularis	0.1220	0.0440	6.9e-05	0.062	NA	0.084	NA	0.102	1.2e-04	NA	8.7e-06	NA	9.5e-07
9	GTEx	Nerve Tibial	0.2071	0.0670	9.9e-05	0.014	NA	0.046	NA	0.034	3.4e-02	NA	3.5e-04	NA	1.9e-03
10	GTEx	Pancreas	0.1340	0.0680	9.2e-03	-0.004	NA	-0.005	NA	-0.005	5.1e-01	NA	5.9e-01	NA	5.9e-01
11	GTEx	Thyroid	0.2020	0.0570	2.6e-06	0.034	NA	0.086	NA	0.065	1.1e-03	NA	3.8e-07	NA	9.9e-06
12	NTR	Blood	0.0397	0.0131	3.5e-06	0.013	0.015	0.031	0.023	0.030	2.6e-05	8.9e-06	2.6e-10	5.7e-08	4.0e-10
13	ROSMAP	Brain Pre-frontal Cortex	0.1772	0.0458	6.6e-13	0.064	0.107	0.133	0.119	0.115	1.1e-08	1.2e-13	9.6e-17	4.5e-15	1.3e-14
14	YFS	Blood	0.1318	0.0271	0.0e+00	0.131	0.147	0.161	0.158	0.160	1.4e-40	1.3e-45	3.1e-50	2.9e-49	6.0e-50
15	TCGA	Breast Invasive Carcinoma	0.1393	0.0547	3.9e-05	0.014	0.034	0.030	NA	0.011	6.6e-04	1.6e-07	5.9e-07	NA	1.6e-03
16	TCGA	Colon Adenocarcinoma	0.3050	0.1060	3.8e-03	-0.005	0.038	0.004	NA	0.002	8.6e-01	2.8e-03	1.8e-01	NA	2.5e-01
17	TCGA	Kidney Renal Clear Cell Carcinoma	0.2358	0.0895	1.1e-04	0.000	0.032	0.022	NA	0.013	3.6e-01	1.4e-04	1.5e-03	NA	1.3e-02
18	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1210	0.0790	3.7e-03	0.014	0.019	0.004	NA	0.020	5.3e-02	2.9e-02	1.7e-01	NA	2.5e-02
19	TCGA	Brain Lower Grade Glioma	0.0945	0.0485	2.0e-04	0.028	0.035	0.027	NA	0.022	3.3e-04	6.8e-05	4.5e-04	NA	1.5e-03
20	TCGA	Lung Squamous Cell Carcinoma	0.0649	0.0420	4.6e-03	-0.002	0.005	-0.002	NA	-0.002	5.9e-01	8.0e-02	6.0e-01	NA	9.4e-01
21	TCGA	Prostate Adenocarcinoma	0.3387	0.0831	1.5e-09	0.085	0.106	0.085	NA	0.077	3.4e-09	3.2e-11	3.2e-09	NA	1.7e-08
22	TCGA	Stomach Adenocarcinoma	0.1070	0.0740	4.4e-03	-0.003	0.010	-0.002	NA	0.000	5.7e-01	6.0e-02	4.6e-01	NA	3.3e-01
23	TCGA	Thyroid Carcinoma	0.4520	0.1390	6.1e-10	0.065	0.124	0.115	NA	0.081	6.2e-07	4.3e-12	3.0e-11	NA	2.8e-08

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23
Had major operations	4.9	5.7	17.0	-2.8	-1.9	-1.6	-1.2	-2.8	-0.3	-2.6	-4.1	-2.7	-2.2	-2.7	-1.4	-1.8	-0.9	-3.5	-2.6	-2.8	-2.6	-2.5	-1.1	-3.5	-1.7	-1.9
Lung FEV1/FVC ratio	4.6	23.3	50.2	7.1	7.0	3.2	3.1	4.9	1.1	4.2	6.0	5.8	0.0	6.6	1.3	3.4	1.6	3.9	3.6	6.7	6.0	4.6	4.9	6.1	5.0	5.5
Medication: Ramipril	4.3	5.5	11.6	2.6	0.3	2.6	1.9	3.2	1.1	3.2	3.0	2.9	1.8	2.1	0.5	2.4	-0.5	3.4	1.6	1.8	3.1	3.1	1.3	3.2	2.2	1.7
Heel T-Score	3.6	28.6	104.0	6.1	1.2	1.6	-1.9	1.2	5.5	1.3	-1.2	0.5	-8.4	4.2	-7.9	6.5	-3.0	-0.2	-4.2	4.4	4.6	5.6	10.2	1.2	9.1	9.9
Hair/balding pattern: Pattern 2	3.3	4.1	10.8	-2.7	-1.4	-1.4	-2.4	-3.3	-0.5	-2.8	-1.8	-1.9	-0.5	-1.7	0.3	-2.6	0.7	-2.4	-0.3	-1.3	-3.0	-2.9	-1.1	-3.1	-2.1	-1.2
Eye problems/disorders: None of the above	3.3	3.9	14.1	2.2	0.3	1.8	1.0	2.7	-0.4	2.7	3.8	2.3	2.9	2.2	0.5	2.1	-0.4	2.6	1.5	1.6	2.5	1.8	0.2	2.3	0.9	0.5
Reaction Time	3.2	6.2	18.2	-2.9	0.2	-2.5	-1.6	-2.9	-0.3	-2.9	-3.3	-3.0	-1.9	-2.1	-1.5	-1.9	-0.6	-4.3	-2.1	-2.5	-3.1	-3.1	-1.0	-4.3	-1.9	-1.8
Respiratory disease	3.2	7.1	13.6	-3.7	-2.1	-2.7	-2.4	-2.6	-2.0	-3.1	-3.7	-2.5	-0.8	-3.3	-0.0	-2.5	0.1	-3.0	-0.9	-2.8	-3.7	-3.5	-2.5	-3.3	-3.1	-2.2
Illnesses of father: Heart disease	3.1	4.4	10.1	-3.2	-2.0	-1.7	0.2	-2.8	-1.5	-2.3	-2.1	-2.9	0.1	-1.8	1.7	-2.6	1.1	-2.1	0.5	-1.2	-2.7	-2.7	-2.0	-2.7	-2.3	-1.9
Blood Red Count	3.0	29.2	114.5	-4.8	-2.2	-6.0	-0.1	3.9	-10.7	4.6	-1.1	-6.0	-0.4	-9.3	-0.6	-1.8	-8.6	-4.2	0.1	-7.0	0.2	-3.4	-10.0	-1.9	-5.4	-6.5
Worry too long after embarrassment	3.0	5.1	19.4	-1.0	-2.2	-0.6	-0.6	-3.4	3.5	-2.7	-3.0	-1.1	-3.3	-0.5	-3.1	-0.1	-0.2	-2.2	-4.4	-1.6	-1.9	-0.3	2.1	-3.4	1.0	0.8
Diabetes diagnosed by doctor	3.0	5.0	11.8	-3.2	-0.2	-2.1	-1.8	-3.0	-0.4	-2.7	-3.4	-3.0	-2.3	-3.3	-0.2	-3.2	0.3	-2.2	0.1	-1.1	-2.9	-2.7	-1.0	-2.6	-2.0	-0.6
Eye problems/disorders: Diabetes related eye disease	2.8	3.1	7.7	-2.8	-1.1	-2.4	-1.1	-1.3	-1.7	-1.2	-2.3	-2.6	-2.3	-2.6	-1.6	-1.2	-1.5	-1.9	-0.3	-1.2	-1.8	-1.7	-1.3	-2.1	-1.0	-0.0
Blood Platelet Count	2.7	31.3	116.6	-0.6	-4.5	-2.7	1.2	7.1	-9.6	9.9	3.7	-3.1	3.3	-7.0	-2.1	4.9	-10.8	0.4	-2.5	-8.0	5.2	1.9	-8.1	2.2	-2.4	-6.6
Townsend deprivation index at recruitment	2.5	3.6	11.8	2.4	1.7	1.8	1.4	2.4	0.2	2.2	2.6	2.0	1.7	1.5	1.1	1.3	0.6	3.0	1.6	1.9	2.4	2.0	0.8	3.4	1.1	0.6
Stomach or abdominal pain in last month	2.5	3.1	13.9	-1.9	-0.8	-0.3	-1.0	-3.5	1.7	-3.7	-2.2	-0.4	-0.6	0.3	1.4	-1.2	3.2	-0.9	-0.0	0.3	-3.0	-1.9	0.4	-1.8	-1.1	-0.2
Allergy	2.5	5.8	15.8	2.8	-0.9	1.2	0.9	3.1	0.0	3.7	4.0	1.7	2.3	2.5	0.7	2.7	-0.6	3.1	2.2	2.3	3.5	2.9	1.1	3.6	2.1	1.5
Medication: Ventolin 100micrograms inhaler	2.5	3.2	8.1	-1.8	-2.1	-1.1	-1.1	-2.8	-0.4	-2.6	-2.2	-1.8	0.0	-1.6	1.2	-2.8	1.7	-1.6	-0.2	-0.7	-2.4	-2.6	-1.1	-1.6	-2.3	-1.5
Mean time to correctly identify matches	2.5	4.8	15.0	-2.4	0.5	-2.1	-1.1	-2.2	-0.1	-2.3	-3.2	-2.5	-2.1	-1.9	-1.9	-1.2	-0.9	-3.8	-2.4	-2.6	-2.6	-2.3	-0.5	-3.9	-1.2	-1.5
Smoking status: Current	2.5	4.0	10.0	2.4	2.1	1.2	0.2	1.3	2.6	1.6	2.4	2.7	1.5	2.8	1.1	2.0	1.2	3.2	0.6	1.7	2.0	2.8	1.7	2.5	2.2	1.1
Multivitamins +/- minerals	2.4	3.1	6.1	-2.1	-0.4	-1.4	-2.4	-2.0	-0.2	-2.1	-2.4	-1.4	-0.6	-1.3	-0.5	-1.9	-0.2	-2.4	-1.0	-1.8	-2.4	-2.3	-1.5	-2.5	-1.9	-1.7
Ulcerative Colitis	2.3	3.3	13.0	1.3	2.0	2.2	1.7	-1.2	2.6	-1.6	1.3	2.3	1.5	3.6	1.8	0.3	3.6	1.3	0.8	2.1	-0.3	-0.0	2.0	0.8	0.3	1.2
Mean Putamen Volume	2.2	2.5	7.3	1.9	1.5	1.0	1.4	2.2	0.6	2.4	1.8	1.9	0.9	1.0	-0.8	2.7	-1.0	2.1	-0.9	-0.5	2.1	2.3	0.7	1.9	1.3	0.7
Vitamin and mineral supplements	2.2	2.9	6.7	2.3	0.9	1.3	1.8	1.9	0.4	1.9	1.7	1.7	-0.6	1.2	-0.2	1.6	0.2	2.1	0.3	1.7	2.3	2.6	1.9	2.3	2.4	1.9
Allergy or Eczema	2.1	5.5	18.4	-2.2	1.6	-1.8	-1.3	-3.4	0.5	-3.8	-4.3	-2.0	-3.1	-1.9	-1.3	-1.8	0.5	-3.0	-1.9	-1.3	-3.2	-2.5	0.3	-3.8	-0.9	0.1
Current tobacco smoking	2.1	3.4	9.3	2.3	1.8	1.1	0.2	1.2	2.1	1.6	2.2	2.5	1.5	2.5	1.0	2.1	1.0	3.0	0.1	1.2	1.9	2.7	1.3	2.4	1.8	0.6
Father’s age at death	2.1	2.8	12.5	-2.3	0.1	-1.5	-1.4	-2.1	-0.7	-1.9	-3.5	-1.6	-2.7	-1.4	-0.4	-1.2	-0.5	-1.9	-1.1	-1.6	-2.0	-1.8	-0.9	-2.0	-1.3	-0.5
Supplements: Calcium	2.1	2.3	7.2	-1.8	-2.6	-1.6	-1.0	-2.7	0.5	-2.3	-2.2	-1.3	-0.8	-0.6	-0.1	-1.0	0.7	-1.2	-0.5	-1.2	-2.3	-1.9	-0.4	-1.9	-1.4	-0.2
Ulcerative Colitis (UC)	2.0	3.7	19.5	0.5	1.2	2.1	2.2	-1.6	2.7	-2.1	1.3	1.8	2.4	2.7	2.7	-1.3	4.4	1.7	1.7	2.2	-1.0	-0.5	1.0	0.6	-0.6	0.1
Waist Hip Ratio (WHR)	2.0	9.1	28.3	-3.0	-3.3	-0.8	-2.4	-4.8	2.5	-4.8	-5.3	-3.2	-4.3	-2.0	-0.9	-3.7	1.8	-3.6	-2.3	-0.7	-3.8	-2.4	0.9	-3.6	-0.5	-0.4
Supplements: Zinc	2.0	2.2	5.3	-1.8	-0.9	-1.1	-1.7	-0.7	-1.7	-0.7	-1.6	-1.4	-0.3	-1.9	1.0	-2.3	-0.3	-1.6	0.7	-1.2	-1.1	-2.0	-2.1	-0.6	-2.3	-2.1
Forced expiratory volume in 1-second (FEV1), Best measure	2.0	6.3	21.3	3.3	3.4	1.7	1.3	2.0	0.7	1.5	3.4	3.7	1.2	4.6	0.5	2.8	0.6	2.1	1.2	3.3	2.6	2.1	2.5	2.9	2.2	2.8
Medication: Gliclazide	2.0	2.2	5.3	-2.2	1.2	-1.6	-1.8	-1.6	-0.5	-1.9	-2.1	-2.3	-1.1	-1.6	0.9	-1.9	0.9	-0.9	1.5	0.1	-2.2	-1.4	-0.6	-1.5	-0.8	0.3
Type 2 Diabetes (T2D) (2018)	1.9	3.6	9.6	-2.7	0.1	-1.2	-0.1	-2.8	0.4	-2.6	-2.7	-2.5	-1.8	-2.6	0.5	-3.1	0.7	-1.5	0.1	-0.9	-2.8	-2.2	-0.8	-2.4	-1.6	-0.3
Diabetes (self-reported)	1.9	2.9	9.9	-2.3	-0.3	-1.5	-1.8	-2.1	-0.2	-1.6	-2.7	-2.4	-2.4	-3.1	-0.7	-1.8	-0.5	-1.6	-0.4	-1.3	-1.9	-1.6	-0.7	-1.9	-1.2	-0.4
Number of children fathered	1.9	2.2	5.3	-1.5	-0.3	-0.1	0.7	-0.9	-0.7	-0.7	-1.7	-1.6	-1.9	-2.3	-0.8	-1.8	-1.4	-2.0	-1.3	-2.1	-1.3	-1.6	-1.8	-1.9	-1.4	-1.6
Handedness (chirality/laterality): Left-handed	1.9	2.3	6.9	1.3	-0.1	0.9	0.4	0.9	0.5	0.7	1.7	1.1	1.7	1.2	1.6	0.7	1.1	2.6	2.0	2.6	1.3	1.5	1.5	2.5	1.4	1.9
Osteoarthritis (self-reported)	1.9	2.5	7.2	1.9	0.1	1.6	1.4	1.9	1.8	2.1	0.9	2.1	-0.8	0.1	-2.2	1.0	-1.2	1.4	-1.5	-0.3	1.9	2.7	1.2	1.6	2.1	0.3
Friendships satisfaction	1.8	2.2	5.4	-1.6	-1.3	-0.7	-0.1	-1.6	-0.9	-1.4	-1.5	-1.2	-0.9	-1.2	0.6	-2.3	0.1	-2.2	-1.3	-1.7	-1.6	-2.0	-1.7	-1.3	-2.0	-2.0
Illnesses of father: None of the above (group 1)	1.8	2.2	4.8	2.2	0.8	1.6	-0.8	1.2	2.0	0.8	0.2	2.1	-1.1	0.9	-2.0	1.3	-0.5	1.4	-1.6	0.7	1.5	2.0	2.2	1.4	2.0	1.8
Illnesses of father: High blood pressure	1.8	2.3	5.3	-1.8	-0.4	-2.0	-0.3	-1.6	-1.5	-1.4	-0.2	-2.0	1.2	-0.3	2.2	-1.9	1.4	-1.1	1.8	-0.1	-1.7	-2.3	-1.3	-1.5	-2.1	-1.0
Worry (Nagel 2018)	1.7	3.5	15.2	-0.4	-1.4	-0.6	-1.5	-3.1	3.9	-3.0	-2.0	-0.3	-1.8	0.7	-1.4	-1.0	1.7	-1.6	-3.6	-0.8	-1.9	-0.4	1.9	-2.2	0.5	0.1
Age when periods started (menarche)	1.7	4.1	27.9	1.7	-0.2	0.5	0.4	1.9	-0.9	1.7	3.2	1.4	5.3	2.7	2.7	0.3	1.3	2.5	2.8	1.1	1.4	0.4	-1.1	2.6	-0.9	-0.9
High blood pressure	1.7	4.7	11.4	2.5	-1.7	2.5	1.0	0.8	3.2	0.4	2.2	2.3	0.9	3.0	-0.0	1.5	2.0	2.4	0.6	2.9	1.8	2.4	3.4	2.0	2.7	2.8
Neuroticism score	1.7	3.5	15.9	-0.4	-0.9	-0.1	-0.5	-3.0	4.0	-2.7	-2.6	0.3	-2.4	0.4	-1.9	-0.5	1.4	-1.4	-4.0	-1.1	-1.6	-0.4	1.9	-1.9	0.4	-0.1
Hair/balding pattern: Pattern 3	1.7	2.5	8.8	1.9	2.3	-0.3	1.7	3.0	-1.0	2.9	2.1	0.8	0.5	0.1	-0.7	1.3	-1.2	1.7	0.3	0.4	2.4	2.1	-0.2	2.1	1.3	0.3
Asthma	1.7	3.3	6.8	-2.6	-1.2	-1.5	-1.0	-1.5	-1.6	-1.9	-2.4	-1.6	-0.2	-2.6	0.2	-1.8	-0.0	-1.9	-0.5	-2.0	-2.4	-2.3	-2.3	-1.9	-2.4	-2.1
Health satisfaction	1.7	2.2	6.8	-1.3	-0.9	0.6	1.2	-2.5	0.8	-2.6	-2.3	-0.7	-1.4	-0.5	1.1	-2.0	2.1	-1.1	0.7	0.3	-2.1	-2.1	0.1	-1.4	-1.4	-0.0
Shortness of breath walking on level ground	1.7	2.1	7.9	-1.1	-1.0	-1.5	-1.4	-2.8	1.9	-2.6	-2.0	-0.4	-0.3	-0.5	0.8	-1.7	2.3	-0.2	-0.6	-0.4	-2.3	-0.9	0.2	-1.0	-0.9	-0.9
Asthma (self-reported)	1.7	3.3	6.5	-2.5	-1.3	-1.7	-1.1	-1.7	-1.5	-2.0	-2.4	-1.6	0.0	-2.4	0.4	-1.8	0.3	-1.7	-0.4	-1.9	-2.5	-2.4	-2.2	-1.9	-2.5	-2.1
Guilty feelings	1.7	2.6	13.6	0.1	-0.8	0.4	0.9	-2.6	3.7	-2.7	-1.8	1.6	-1.2	1.8	-0.6	-0.1	2.6	0.1	-2.3	0.1	-1.3	-0.2	2.1	-0.7	0.2	0.6
Alcohol usually taken with meals	1.6	2.5	7.3	-2.1	0.7	-0.8	0.6	-1.4	-0.9	-1.7	-1.9	-1.6	-1.1	-1.4	0.7	-2.4	0.0	-2.3	0.2	-1.0	-1.9	-2.7	-2.0	-2.2	-2.1	-0.9
Medication: Ibuprofen (e.g. Nurofen)	1.6	2.0	7.0	2.1	0.9	2.6	1.1	1.6	1.8	1.5	1.2	2.0	-0.2	1.1	0.2	0.2	0.0	1.1	-0.2	1.3	2.0	1.8	1.1	1.9	1.5	0.4
Exposure to tobacco smoke at home	1.6	1.8	7.3	-1.0	1.8	-0.1	0.9	-0.5	-0.5	-1.1	0.0	-1.6	1.3	0.9	2.7	-1.9	1.6	-0.6	2.1	0.5	-1.0	-1.6	-1.3	-0.1	-1.6	-1.4
Number of operations (self-reported)	1.6	2.4	8.9	-1.3	-1.7	0.6	-0.3	-1.6	1.2	-1.4	-2.6	-1.7	-3.0	-1.2	-1.3	-1.5	-0.6	-2.8	-1.8	-1.0	-1.1	-1.3	0.2	-2.3	-0.2	-0.5
Fractured/broken bones in last 5 years	1.6	2.1	5.6	1.5	-0.1	2.1	2.2	1.4	1.2	1.4	2.4	1.4	0.9	1.9	0.8	1.5	0.0	1.5	1.0	1.3	1.6	1.4	1.1	1.4	1.4	1.3
Alzheimer’s Disease (in mother)	1.5	1.8	5.6	-1.6	-2.1	-1.3	0.5	-2.4	0.2	-1.6	-1.9	-1.5	-0.4	-0.8	-0.3	-0.8	0.2	-1.5	-1.5	-1.4	-1.5	-1.4	-0.5	-2.1	-1.0	-1.0
Qualifications: CSEs or equivalent	1.5	2.0	6.4	2.1	-0.1	0.5	0.7	2.3	0.4	2.5	2.5	0.6	0.6	-0.4	-0.5	1.0	-1.2	1.6	-0.1	0.9	2.5	2.0	0.6	2.1	1.3	0.5
Hayfever, allergic rhinitis or eczema	1.5	3.3	9.9	-1.6	2.1	-1.1	-0.8	-2.6	0.4	-3.1	-3.1	-1.2	-2.2	-1.4	-0.5	-2.0	1.0	-2.3	-1.1	-0.9	-2.6	-2.1	0.2	-2.7	-1.0	-0.1
Nervous feelings	1.5	2.7	15.0	0.1	-0.8	0.0	-1.4	-2.5	3.9	-2.3	-1.4	0.3	-1.6	1.4	-1.2	-0.4	1.7	-1.2	-3.6	-0.4	-1.1	0.2	2.2	-1.4	1.0	0.1
Had other major operations	1.5	1.8	4.2	-1.8	-2.0	-1.6	-1.5	-0.3	-1.2	0.0	-1.1	-1.9	-0.9	-1.4	0.0	-1.4	-1.3	-2.1	-0.5	-1.4	-0.7	-1.4	-1.9	-1.1	-1.3	-1.6
Fluid intelligence score	1.5	3.2	9.9	-2.4	-3.1	-0.6	-1.8	-2.3	-0.6	-2.5	-3.0	-0.5	-0.8	-1.5	0.0	-1.8	0.7	-1.9	-0.7	-1.3	-2.6	-2.2	-0.8	-2.1	-1.7	-0.9
Leg fat percentage (right)	1.5	5.4	18.2	-2.7	0.4	-1.8	-1.0	-2.2	-1.2	-2.3	-3.9	-3.2	-4.3	-3.9	-0.1	-3.0	-0.3	-3.0	0.1	-0.8	-2.4	-2.5	-1.3	-2.5	-1.3	-0.4
Wheeze or whistling in the chest in last year	1.5	2.7	12.8	-1.1	-0.4	-0.8	-0.9	-2.0	0.0	-2.5	-1.3	-0.9	0.9	-1.1	2.4	-3.6	2.6	-0.6	1.6	1.1	-1.9	-2.2	-0.6	-0.9	-1.8	-1.0
Hypertension (Self-reported)	1.5	4.3	10.5	2.4	-1.4	2.4	1.4	0.8	3.1	0.4	2.0	2.3	0.7	2.8	-0.2	1.5	1.7	2.3	0.5	2.7	1.7	2.3	3.2	1.9	2.6	2.7
Long-standing illness, disability or infirmity	1.5	2.3	6.6	-2.0	-0.4	-0.3	-1.1	-2.4	1.1	-2.5	-2.6	-1.2	-1.3	-1.6	0.0	-2.1	0.9	-1.6	-0.5	-0.6	-2.4	-1.8	-0.1	-2.2	-1.0	-0.3
Breast cancer (self-reported)	1.5	1.8	9.7	-0.8	0.9	-0.6	0.8	1.7	-2.4	2.0	0.3	-0.5	0.2	-1.6	-1.2	1.5	-3.1	-0.3	-0.9	-1.9	0.9	0.4	-1.8	-0.3	-0.4	-1.0
Medication: Blood pressure	1.5	2.8	9.1	2.2	-0.9	1.6	0.9	1.2	1.3	0.9	1.7	1.7	0.5	1.7	0.6	0.2	1.3	2.1	2.0	3.0	1.7	1.6	2.1	2.3	1.7	2.2
Medication: Lisinopril	1.5	2.0	8.3	1.9	-0.2	1.5	0.9	0.1	2.1	0.1	0.5	0.5	-1.5	1.4	-0.9	0.5	0.8	0.8	-0.1	1.9	1.2	1.3	2.9	1.1	2.0	2.7
Medication: Omeprazole (e.g. Zanprol)	1.5	1.9	9.1	-1.0	-1.1	0.1	1.0	-1.8	0.1	-2.0	-0.4	0.4	1.4	0.2	2.5	-1.9	3.0	0.8	2.0	1.3	-1.6	-1.1	-0.0	0.2	-1.2	-0.1
Irritable Bowel Disease (IBD)	1.4	3.4	16.4	0.8	0.1	2.3	2.5	-1.8	3.4	-2.1	1.1	1.7	1.5	2.6	2.3	-0.7	4.1	1.4	1.2	2.4	-0.8	0.0	1.5	0.6	0.3	0.7
Relative age of first facial hair	1.4	2.9	6.1	2.1	-0.2	1.1	1.5	1.3	2.1	1.5	2.2	1.8	1.5	2.5	-0.1	1.7	0.5	2.2	0.3	1.6	2.1	2.4	2.0	1.9	2.1	1.4
Taking other prescription medications	1.4	2.2	4.8	-2.2	-1.7	0.1	0.6	-2.1	0.1	-1.9	-1.5	-0.5	0.5	-1.0	0.9	-2.2	1.1	-1.0	-0.8	-1.4	-2.1	-1.9	-1.3	-1.8	-2.0	-1.9
Heel bone mineral density (BMD) T-score, automated (left)	1.4	3.2	13.8	2.2	0.2	-0.9	-1.9	-0.7	2.2	-0.9	-0.9	0.7	-2.0	2.5	-0.9	1.8	0.8	0.1	-0.8	2.5	0.8	1.3	3.7	0.6	2.7	3.2
Impedance of leg (left)	1.4	7.0	24.3	-3.3	-3.8	-1.8	-0.4	-4.9	-0.2	-3.7	-2.3	-2.6	1.0	-0.6	1.2	-2.6	2.0	-2.1	-1.3	-2.5	-4.0	-3.3	-1.3	-3.6	-3.1	-2.2
Illnesses of mother	1.4	1.8	6.8	0.8	2.3	-0.7	0.5	2.5	-0.7	2.6	2.0	0.5	0.8	0.0	-1.0	1.8	-2.0	0.4	-0.5	-1.2	1.6	1.1	-0.8	0.8	0.5	-0.5
Glaucoma (self-reported)	1.4	1.6	7.6	0.8	0.9	-0.0	-2.8	-0.7	2.2	-1.1	-1.9	0.6	-2.6	-0.4	0.3	-0.7	0.9	-0.1	0.2	1.5	-0.1	0.5	1.7	0.8	1.3	1.6
Seen a psychiatrist for nerves, anxiety, tension or depression	1.4	1.9	12.2	0.6	0.2	1.5	-1.1	-1.7	3.5	-1.9	-1.2	1.4	-0.6	1.6	0.4	-0.0	2.4	-0.1	-1.0	1.2	-0.4	-0.0	2.1	0.3	0.6	0.8
Medication: Blood pressure	1.4	2.5	5.8	1.6	-0.9	2.4	1.1	1.2	2.3	1.1	1.7	1.3	0.0	1.0	-1.5	2.4	-0.2	1.5	-1.0	0.5	1.5	2.3	2.0	0.8	2.3	1.9
Angina (self-reported)	1.4	1.8	6.1	-1.3	-0.2	-0.0	0.5	-1.0	-0.7	-0.7	-1.4	-1.1	-0.9	-2.1	-2.2	0.6	-1.0	-1.6	-2.4	-2.5	-0.9	-0.9	-0.7	-1.8	-0.9	-1.4
Medication: Allopurinol	1.4	1.9	6.5	1.2	1.1	1.1	1.1	1.8	0.3	1.9	1.7	1.1	0.2	1.0	-2.5	1.6	-2.4	-0.1	-2.2	-1.2	1.6	1.2	0.5	-0.4	1.0	0.2
Heart disease (mother)	1.4	1.7	6.0	-0.7	-0.3	-0.3	-1.2	-2.4	0.1	-2.4	-2.2	-0.6	-1.7	-0.4	-0.3	-1.0	0.9	-2.3	-0.7	0.3	-1.6	-1.9	0.3	-1.7	-0.7	-0.1
Illnesses of siblings: Diabetes	1.4	1.7	5.2	-1.1	0.5	-0.8	-1.0	-2.2	1.0	-1.9	-2.3	-1.0	-2.2	-1.6	-1.4	-1.1	0.1	-0.9	-1.4	-0.7	-1.6	-0.6	0.4	-1.8	-0.1	0.4
Average weekly red wine intake	1.4	2.1	4.9	-1.5	-0.4	-1.4	-2.2	-2.0	-0.5	-2.0	-2.0	-1.7	-1.3	-1.1	0.2	-1.9	0.1	-2.2	0.3	-0.1	-1.7	-2.1	-0.3	-2.0	-0.9	0.4
Leg fat percentage (left)	1.4	5.2	16.7	-2.7	0.3	-1.6	-0.8	-2.3	-1.0	-2.2	-3.9	-3.2	-4.1	-3.8	0.1	-3.0	-0.2	-3.0	0.1	-1.0	-2.3	-2.6	-1.4	-2.5	-1.5	-0.7
Major Depression (MDD)	1.3	1.5	7.0	-0.4	0.8	-0.3	0.8	-1.6	0.9	-1.3	-1.8	0.6	-1.8	-1.2	-1.2	-1.4	-0.1	-1.5	-2.6	-1.5	-0.9	-1.0	0.0	-1.5	-0.8	-0.9
Coronary Artery Disease (CAD)	1.3	1.6	4.0	1.7	1.5	1.0	-0.2	1.2	0.3	0.7	1.7	0.9	1.5	1.9	1.1	0.7	1.2	0.8	1.7	2.0	1.4	0.5	0.9	1.7	0.6	1.3
HDL Cholesterol	1.3	2.2	5.3	-1.7	-2.3	-1.0	-1.3	-1.3	-0.7	-0.8	-2.0	-2.3	-1.4	-1.8	-0.4	-2.0	-1.0	-1.7	-0.7	-1.6	-1.2	-1.4	-1.2	-1.7	-1.1	-1.4
Angina	1.3	1.7	5.5	-1.3	0.1	0.1	0.6	-1.1	-0.7	-0.8	-1.5	-1.1	-1.1	-2.0	-2.1	0.3	-0.8	-1.8	-2.4	-2.3	-0.9	-1.0	-0.5	-1.7	-0.9	-1.3
Impedance of leg (right)	1.3	6.2	23.4	-3.3	-3.3	-1.7	-0.5	-4.8	-0.3	-3.9	-2.4	-2.4	0.7	-0.6	1.0	-2.5	2.2	-1.9	-1.0	-1.8	-4.0	-3.1	-0.9	-3.4	-2.6	-1.3
Medication: Atenolol	1.3	1.7	7.1	1.4	-0.7	1.3	1.0	1.6	0.3	2.0	1.7	1.3	0.5	0.5	-1.0	2.7	-1.3	1.3	-1.2	-0.7	1.7	1.7	-0.0	1.0	1.0	-0.3
Frequency of tenseness / restlessness in last 2 weeks	1.3	2.0	8.9	-0.5	-0.6	0.6	-0.7	-1.9	1.9	-1.7	-2.1	-0.8	-2.4	-0.6	-2.0	0.4	0.2	-1.1	-3.0	-0.8	-1.0	-0.1	1.4	-1.9	0.6	0.5
Hayfever/allergic rhinitis (self-reported)	1.3	1.7	4.1	-1.5	-0.1	-1.4	-0.3	-2.0	-1.1	-1.9	-1.5	-1.6	-0.6	-0.4	1.3	-1.5	0.8	-1.7	0.6	-0.4	-1.9	-2.0	-0.6	-1.5	-1.5	-0.6
Worrier / anxious feelings	1.3	2.4	9.6	-0.9	-2.1	0.0	-0.7	-2.6	3.1	-2.4	-1.9	0.1	-1.4	0.4	-1.1	-0.3	1.6	-0.6	-2.8	-0.6	-1.6	-0.1	1.6	-1.9	0.5	0.1
Frequency of tiredness / lethargy in last 2 weeks	1.3	2.0	5.0	-1.6	-1.0	0.9	0.2	-1.7	2.1	-2.1	-2.0	-0.5	-1.2	-0.9	-0.7	-1.3	0.9	-1.7	-2.1	-1.4	-2.0	-0.9	-0.2	-2.2	-0.4	-1.5
Body fat percentage	1.3	5.0	16.2	-2.6	0.0	-1.8	-0.9	-2.2	-0.6	-2.3	-3.9	-3.0	-4.0	-3.4	-0.3	-2.9	-0.0	-3.1	-0.3	-1.2	-2.5	-2.4	-1.2	-2.7	-1.3	-0.8
Emphysema/chronic bronchitis	1.3	1.4	4.1	-0.9	-0.4	-0.2	-1.4	-1.4	1.4	-1.5	-1.6	0.1	1.0	-0.5	0.1	-1.0	1.3	-0.4	-1.8	-2.0	-1.5	-0.9	-0.7	-0.7	-1.5	-1.7
Qualifications: NVQ or HND or HNC or equivalent	1.3	1.5	4.6	-2.1	0.4	-0.5	-0.0	-1.6	-0.3	-1.3	-1.6	-1.8	-0.5	-1.7	0.1	-1.5	-0.1	-0.8	0.6	-0.7	-1.9	-1.6	-0.9	-2.0	-1.2	-0.3
Commuting to job workplace: Car/motor vehicle	1.3	1.4	5.1	0.9	-0.1	1.5	0.5	0.4	2.1	0.1	0.4	0.5	-1.3	1.0	-1.3	0.9	-0.5	0.5	-0.6	1.3	0.9	1.4	2.1	0.2	2.2	2.3
Loneliness, isolation	1.3	1.8	5.5	-0.9	1.1	-1.8	-1.0	-0.3	0.1	-0.6	-1.8	-0.2	-2.3	-1.4	-1.6	-0.7	-1.5	-2.2	-2.3	-1.8	-0.6	-0.8	-0.6	-1.7	-0.4	-0.9
Eye problems/disorders: Cataract	1.3	1.5	4.6	-1.5	-0.3	-1.0	0.6	-1.8	0.2	-1.7	-1.4	-0.7	0.1	-0.8	1.1	-2.1	1.6	-0.5	-0.0	-1.1	-1.9	-1.4	-0.9	-1.1	-1.5	-1.2
Eye problems/disorders: Glaucoma	1.3	1.6	8.2	0.7	1.3	0.2	-2.5	0.3	1.5	-0.1	-1.4	0.7	-2.9	-0.6	-1.2	0.8	-0.8	-0.9	-1.1	0.4	0.5	0.9	1.6	0.2	1.8	1.5
Irritability	1.3	2.3	11.1	0.6	1.5	1.9	0.4	-1.2	2.9	-2.1	-0.5	1.6	0.1	2.4	0.4	-0.7	3.3	0.7	0.1	1.6	-1.0	-0.1	2.3	0.5	0.3	1.0
Vascular/heart problems diagnosed by doctor	1.3	3.4	9.3	-2.0	1.5	-2.5	-0.9	-0.5	-3.0	-0.1	-1.9	-2.0	-1.0	-2.7	0.2	-1.5	-2.0	-1.9	-0.2	-2.3	-1.4	-1.9	-2.9	-1.5	-2.2	-2.0
Neuroticism (Nagel 2018)	1.2	2.9	14.6	-0.2	-0.4	-0.1	-0.6	-2.6	3.8	-2.8	-2.1	0.1	-2.3	0.6	-1.0	-1.0	1.7	-1.7	-3.0	-0.2	-1.6	-0.7	1.8	-1.8	0.3	0.3
Bipolar Disorder (2011)	1.2	1.2	7.3	-0.2	1.9	-0.7	-0.2	-0.7	0.2	-1.2	-1.6	-0.4	-2.7	-0.9	-0.8	-0.8	0.3	-1.9	-1.4	0.3	-0.5	-0.7	0.7	-1.3	0.4	0.1
Lupus	1.2	1.8	6.2	-1.1	0.2	-1.4	-1.9	-1.9	0.1	-2.5	-1.6	-2.1	-0.3	-0.0	0.7	-1.9	1.7	-0.9	1.1	1.1	-2.0	-1.4	0.2	-0.9	-0.6	0.1
Blood White Count	1.2	8.6	26.6	-2.9	-2.6	-2.8	-0.6	0.9	-4.7	1.8	-0.7	-3.4	0.4	-4.9	0.0	-0.0	-4.2	-2.8	-1.4	-4.6	-0.5	-1.9	-5.2	-2.1	-3.0	-4.5
Neuroticism	1.2	2.9	12.3	-0.4	-0.7	-0.5	-0.8	-2.8	3.5	-2.6	-2.7	0.3	-2.3	0.1	-1.5	-0.6	1.2	-1.2	-3.1	-1.0	-1.8	-0.5	1.7	-1.8	0.3	0.1
Hearing difficulty/problems: Yes	1.2	1.8	5.7	1.8	0.8	0.8	-0.3	1.9	-0.8	1.8	2.4	1.2	0.6	1.0	1.3	0.6	0.4	0.9	1.2	1.6	2.2	1.2	0.4	2.4	0.8	-0.2
Tinnitus: Yes, but not now, but have in the past	1.2	1.3	2.9	-0.4	0.5	-1.6	-1.2	-1.3	1.0	-1.6	-1.6	-1.2	-1.6	-0.4	-0.2	-1.7	0.7	-1.7	-1.4	-0.6	-1.1	-1.0	0.3	-1.6	-0.2	-0.6
Heel bone mineral density (BMD) T-score, automated (right)	1.2	2.8	12.8	1.7	0.4	-0.9	-1.0	-0.6	2.0	-0.7	-1.0	0.6	-1.8	2.1	-1.7	2.1	0.1	0.3	-1.0	1.8	0.6	1.4	3.5	-0.0	2.7	3.6
Happiness	1.2	1.4	5.2	-0.7	-1.1	-0.9	-1.6	-1.3	0.4	-1.1	-1.9	-1.7	-1.5	-1.2	0.1	-0.9	-0.2	-2.3	-1.3	-0.9	-0.8	-1.4	-0.2	-1.1	-0.8	-0.4
Tense / ‘highly strung’	1.2	2.0	12.4	0.2	-1.3	0.4	-1.2	-2.3	3.5	-2.2	-1.4	0.4	-0.9	1.1	-0.7	-0.6	2.2	-0.2	-1.7	0.4	-0.9	-0.1	2.2	-0.8	0.6	0.7
Loud music exposure frequency	1.2	1.3	4.8	1.1	1.8	0.3	0.4	1.1	1.4	0.8	0.4	1.0	-1.0	0.0	-2.2	1.7	-0.9	0.2	-2.1	-0.7	1.1	1.5	1.1	-0.0	1.4	0.2
Headache pain in last month	1.2	2.0	5.4	0.9	-1.6	1.6	0.1	0.1	1.4	0.3	1.7	1.7	2.1	2.3	2.3	-0.7	2.3	2.0	1.3	1.1	0.6	0.5	0.1	2.0	-0.4	-0.7
Medication: Amlodipine	1.2	1.7	7.8	0.9	-1.1	1.4	-0.2	-0.5	2.8	-0.8	0.5	0.7	0.0	1.6	-0.6	0.6	1.5	1.0	0.4	1.7	-0.1	0.9	2.5	0.1	1.6	2.4
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.2	4.9	0.7	1.4	0.5	0.5	1.0	0.3	0.9	2.1	1.2	2.2	1.1	0.9	0.3	0.7	1.8	1.8	0.8	0.6	0.9	0.2	1.0	0.5	0.8
Age started oral contraceptive pill	1.2	1.4	4.4	-1.7	-1.4	-1.3	0.4	-1.3	-0.6	-1.2	-2.1	-1.4	-0.9	-1.3	0.2	-1.4	0.3	-0.8	-0.5	-1.4	-1.5	-1.1	-1.3	-0.8	-1.3	-1.6
Neuroticism (2016)	1.1	1.6	6.0	0.1	-1.6	0.2	1.0	-2.4	2.4	-1.9	-1.2	0.4	0.1	0.5	0.5	-1.3	2.4	0.1	-1.9	-0.6	-1.2	-0.6	0.7	-0.1	-0.8	-1.0
Fed-up feelings	1.1	2.0	4.4	1.9	-0.4	1.8	1.9	1.8	1.5	1.7	1.9	2.1	1.2	1.3	0.1	1.2	0.3	1.2	-0.4	0.6	1.9	1.6	0.5	2.1	0.9	-0.4
Waist circumference	1.1	4.1	16.0	-2.4	0.4	-1.8	-1.2	-1.2	-0.9	-1.8	-3.5	-2.3	-3.4	-4.0	0.3	-3.1	0.0	-2.4	0.4	-0.9	-2.1	-2.0	-1.8	-1.7	-1.3	-1.3
Number of incorrect matches in round	1.1	1.9	5.8	-0.1	2.3	0.2	-1.1	-0.9	1.2	-2.1	-1.3	0.3	-0.7	0.4	1.9	-2.4	2.3	-0.7	1.9	2.0	-1.2	-1.2	0.8	-0.1	-0.3	0.8
Forced expiratory volume in 1-second (FEV1)	1.1	3.8	13.7	2.4	2.0	1.3	0.4	1.6	0.2	1.3	2.9	3.0	2.0	3.7	1.2	1.6	0.8	1.8	1.5	2.7	2.0	1.4	1.3	2.7	1.3	1.7
Peak expiratory flow (PEF)	1.1	2.5	7.3	2.6	1.6	0.7	0.2	2.2	-0.9	1.9	1.7	1.2	0.4	2.1	0.8	1.5	-0.6	0.6	1.5	2.3	2.6	0.9	0.8	2.7	1.1	1.5
Medication: Ibuprofen	1.1	1.4	8.7	1.5	1.2	3.0	0.7	0.8	2.1	0.8	0.4	1.7	-0.6	0.6	-0.2	0.0	0.0	0.5	-0.5	0.9	1.3	1.2	1.2	1.0	1.2	0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.3	9.2	0.1	-0.9	0.1	1.6	0.9	-3.0	1.4	1.4	-1.0	1.5	0.0	1.1	0.2	-1.0	0.3	0.9	-0.3	0.7	-0.5	-1.6	0.9	-1.2	-0.8
Suffer from ‘nerves’	1.1	1.7	9.0	-0.5	-0.8	-0.3	-1.2	-1.9	2.2	-1.8	-1.4	0.1	-1.1	0.3	-0.8	-0.8	1.1	-1.5	-3.0	-1.2	-1.2	-0.5	0.8	-1.7	-0.1	-0.9
Age at last live birth	1.1	1.6	5.5	-1.7	0.8	-1.0	-1.0	-0.8	-0.6	-1.2	-1.4	-1.1	-1.4	-1.6	-2.0	-0.3	-1.3	-1.3	-1.5	-1.4	-1.6	-0.6	-0.6	-2.4	-0.1	-0.2
Forced expiratory volume in 1-second (FEV1), predicted	1.1	2.2	12.3	1.5	3.5	1.2	0.8	1.3	1.2	0.7	1.8	2.5	0.3	1.9	-0.6	0.6	0.1	1.8	0.4	1.4	1.0	1.5	1.3	1.3	1.3	1.6
Average weekly champagne plus white wine intake	1.1	1.6	6.7	-0.4	-0.4	0.1	1.2	0.7	-1.5	1.0	0.5	-0.2	-0.1	-1.1	-1.4	0.9	-2.2	-1.7	-1.8	-2.6	0.1	-0.6	-1.5	-1.6	-0.7	-1.7
Medication: Bendroflumethiazide	1.1	1.7	6.9	1.8	-0.4	1.1	0.7	0.0	2.1	-0.3	1.0	0.6	-0.9	1.5	-0.6	0.6	0.8	0.2	-0.4	2.0	1.1	1.1	2.6	0.5	2.1	2.4
Diastolic blood pressure, automated reading	1.1	3.5	8.4	2.5	0.1	1.2	0.3	2.5	0.0	2.9	2.7	1.3	-0.0	1.3	-1.1	1.8	-1.1	1.9	0.4	1.8	2.9	2.6	1.8	2.0	2.5	2.2
Systolic Blood Pressure	1.0	4.8	19.4	3.1	-0.8	0.7	-1.1	0.8	1.5	0.8	2.5	0.9	-0.2	3.3	-0.7	2.1	0.7	1.7	0.8	3.6	2.2	2.2	3.7	1.4	3.3	4.4
Smoking Status	1.0	2.4	6.0	1.8	1.5	2.3	0.5	1.1	2.5	1.5	1.9	2.1	1.4	1.6	0.6	0.9	0.7	2.4	0.4	0.9	1.7	2.1	1.1	2.0	1.4	0.6
Sensitivity / hurt feelings	1.0	1.7	11.8	0.3	0.2	-0.1	-1.6	-1.1	3.4	-1.0	-1.1	0.8	-2.0	0.7	-1.6	0.3	0.5	-0.6	-2.3	0.1	-0.3	0.6	2.0	-1.1	1.4	0.7
Other serious medical condition/disability diagnosed by doctor	1.0	1.3	7.0	-0.2	-0.1	0.6	-0.9	-2.0	1.5	-1.9	-0.9	1.2	-0.9	1.2	0.7	-0.5	2.6	0.0	-0.0	0.9	-1.1	-0.3	1.6	-0.3	0.3	0.7
Systolic blood pressure, automated reading	1.0	2.8	9.5	2.3	-0.5	0.4	-0.9	1.2	0.3	1.7	1.3	-0.0	-1.7	0.9	-1.6	2.4	-1.2	1.0	-0.2	1.7	2.2	2.1	2.5	1.0	2.8	3.1
Diabetes (father)	1.0	1.2	4.5	-0.6	0.1	-0.5	0.2	-1.6	-0.6	-1.2	-0.6	-1.0	0.4	0.2	2.1	-1.9	1.6	-0.2	2.1	0.7	-1.0	-1.7	-0.5	-0.0	-1.4	0.1
Trunk fat percentage	1.0	3.9	12.7	-2.4	-0.2	-1.6	-0.9	-2.1	-0.3	-2.1	-3.4	-2.5	-3.6	-2.9	-0.3	-2.6	0.2	-2.6	-0.2	-1.1	-2.4	-2.1	-0.9	-2.4	-1.1	-0.6
Mouth/teeth dental problems	1.0	1.5	3.9	1.7	1.6	1.4	1.1	1.2	0.3	1.0	0.7	2.0	-0.4	0.7	-1.5	1.8	-0.3	1.2	-0.7	0.4	1.3	1.5	1.4	1.2	1.2	1.4
Arm fat percentage (right)	1.0	3.9	20.5	-2.1	0.6	-1.6	-1.0	-1.3	-0.7	-1.4	-3.5	-2.9	-4.5	-3.4	-1.0	-2.3	-0.9	-2.7	-0.2	-0.7	-1.6	-1.5	-0.8	-2.0	-0.4	-0.1
Time employed in main current job	1.0	1.1	3.8	-0.2	-1.5	-0.5	-0.1	-1.7	1.7	-1.4	-1.7	-0.5	-1.5	0.0	-1.2	-0.2	0.6	-1.2	-1.9	-0.9	-0.9	-0.5	0.8	-0.9	-0.1	0.1
Falls in the last year	1.0	1.3	7.0	-0.7	0.0	1.9	1.5	-1.7	1.2	-1.8	-1.0	0.3	-0.6	0.5	0.7	-1.6	2.6	-0.5	0.3	0.4	-1.2	-0.9	0.3	-0.4	-0.6	-0.8
Gout (self-reported)	1.0	1.4	4.6	1.2	1.5	0.3	0.4	1.6	-0.3	1.6	1.3	1.2	0.4	0.6	-2.1	1.8	-2.1	0.2	-2.0	-1.1	1.3	1.0	0.1	-0.3	0.7	0.0
High blood pressure (siblings)	1.0	1.5	5.4	1.4	-0.2	1.4	0.8	-0.0	2.0	-0.1	-0.2	1.6	-0.8	1.8	-0.1	1.5	0.8	0.3	-0.8	1.1	1.1	1.2	2.3	1.1	1.6	1.5
Age at first live birth	1.0	1.8	5.7	-2.1	-0.5	-1.2	-1.0	-1.5	-0.4	-1.7	-2.1	-1.4	-0.9	-1.8	-1.2	-1.0	-0.7	-0.8	-0.9	-1.5	-2.1	-0.9	-0.9	-2.4	-0.5	0.1
Chest pain or discomfort	1.0	1.5	7.6	-1.2	-1.1	-0.3	-1.7	-1.8	1.0	-2.2	-1.0	-0.3	-0.0	0.4	1.2	-1.3	2.8	-0.6	-0.1	0.3	-1.9	-1.1	-0.1	-0.8	-0.8	-0.8
Commuting to job workplace: Walk	1.0	1.0	3.5	-1.3	0.0	-1.9	-1.0	-0.7	-0.7	-1.0	-0.9	-1.2	0.5	-1.2	0.7	-1.8	0.6	-0.6	0.9	-0.1	-1.3	-1.1	-1.1	-0.8	-1.1	-0.8
Back pain experienced in last month	1.0	1.4	4.6	-1.0	-0.6	-0.4	-1.2	-1.8	1.2	-2.0	-1.1	-1.2	-0.4	0.0	1.5	-2.2	2.0	-0.9	1.1	1.5	-1.2	-1.2	0.4	-0.3	-0.4	-0.5
Osteoporosis (self-reported)	1.0	1.3	5.0	-0.7	1.5	-0.7	1.0	0.5	-0.9	0.1	1.1	-0.2	1.8	-0.1	2.2	-0.6	1.1	-0.1	1.7	-0.0	-0.5	-0.9	-1.8	0.0	-1.4	-1.8
Unable to work because of sickness or disability	1.0	1.3	4.9	0.8	1.5	1.3	1.4	0.9	1.6	1.1	0.3	0.7	-1.5	-0.7	-1.9	0.6	-0.7	0.6	-2.2	-0.7	1.1	1.6	0.7	0.4	1.3	-0.1
Alzheimer’s Disease (including proxy)	0.9	1.2	5.9	-0.7	-1.6	-1.1	0.0	-1.5	0.6	-0.3	-1.4	-1.2	-1.4	-0.7	-1.1	0.7	-0.6	-1.3	-2.4	-1.5	-0.5	-0.2	0.0	-1.4	0.2	-1.1
HbA1C	0.9	1.0	5.5	-0.9	-1.3	-0.9	0.1	0.7	-2.3	1.4	0.9	-0.8	1.5	-0.5	0.8	-0.2	-1.1	-0.2	0.7	-0.2	0.4	-0.3	-1.7	0.7	-0.8	-1.0
Diabetes (mother)	0.9	1.1	3.8	0.6	-0.6	1.4	-0.5	-1.6	1.4	-1.6	-1.0	-0.1	-1.3	0.1	0.4	-0.8	1.4	-0.3	0.6	1.9	-0.2	-0.3	1.8	0.1	0.6	1.5
Maternal smoking around birth	0.9	1.3	4.9	1.0	-0.3	1.5	1.2	1.1	1.5	1.0	1.9	2.2	1.6	1.0	0.8	0.9	0.3	1.4	0.5	0.7	1.1	1.0	0.4	1.6	0.4	0.1
Forced vital capacity (FVC), Best measure	0.9	3.5	13.2	2.1	2.5	1.4	0.6	1.1	1.0	0.5	2.5	3.2	1.9	3.6	0.8	1.7	1.1	1.8	1.1	2.5	1.4	1.2	1.6	2.1	1.2	1.8
Medication for pain relief, constipation, heartburn	0.9	1.5	9.9	-1.0	-0.6	-3.1	-1.2	-0.1	-1.2	0.0	-0.9	-1.8	-1.2	-1.3	-1.7	-0.3	-1.7	-1.1	-1.2	-1.2	-0.6	-0.2	-0.6	-1.3	0.0	0.1
Medication: Omeprazole	0.9	1.1	4.0	-1.0	-0.7	0.1	0.9	-1.3	-0.3	-1.3	-0.5	0.0	1.0	-0.1	2.0	-1.4	1.9	0.5	1.6	0.8	-1.2	-1.0	-0.5	0.2	-1.2	-0.4
Whole body fat mass	0.9	3.6	13.0	-2.1	1.4	-1.6	-0.8	-1.3	-0.7	-1.9	-3.3	-2.0	-3.6	-3.1	0.1	-2.9	0.2	-2.4	0.7	-0.4	-2.0	-2.1	-1.2	-1.8	-1.1	-0.4
Leg fat mass (right)	0.9	3.5	10.8	-2.2	1.6	-1.5	-0.7	-1.4	-0.9	-2.0	-3.2	-2.0	-3.1	-3.3	0.6	-3.0	0.5	-2.1	1.1	-0.2	-2.1	-2.2	-1.4	-1.6	-1.4	-0.5
Medication: Aspirin	0.9	1.2	3.3	-1.1	-0.6	1.4	-0.8	-1.7	0.1	-1.5	-1.2	-0.8	-0.3	-0.5	0.2	0.3	0.6	-1.8	-1.0	-1.0	-1.4	-1.6	-0.4	-1.6	-1.1	-1.2
Ever had prostate specific antigen (PSA) test	0.9	1.1	3.4	-1.0	-1.0	-1.1	-0.2	-0.9	0.7	-1.0	-1.0	-1.8	-1.3	-0.8	-0.5	-1.2	-0.2	-1.9	-1.1	-0.8	-0.8	-1.0	-0.2	-1.8	-0.2	-0.4
Leg fat mass (left)	0.9	3.4	9.7	-2.1	1.5	-1.4	-0.5	-1.4	-0.8	-1.9	-3.1	-1.9	-3.0	-3.1	0.7	-3.0	0.5	-2.1	1.1	-0.2	-2.0	-2.2	-1.4	-1.6	-1.4	-0.6
Verbal and Numeric Reasoning (VNR)	0.8	2.0	7.4	-1.4	-2.7	-0.1	-1.3	-2.5	0.7	-2.4	-2.6	-0.1	-1.2	-0.3	-0.3	-0.4	1.3	-1.1	-1.1	-0.9	-2.0	-1.3	0.2	-1.3	-0.9	-0.3
Pack years adult smoking proportion	0.8	1.3	7.0	0.8	1.6	1.2	-1.6	-0.1	2.6	-0.2	0.4	1.1	0.5	0.6	-1.0	1.7	0.7	0.7	-2.0	-0.2	0.3	1.1	1.6	0.1	0.9	0.1
Diverticular disease/diverticulitis (self-reported)	0.8	1.0	4.5	-0.2	-1.7	0.8	-0.7	-1.8	2.1	-1.4	-1.0	-0.1	-0.6	0.2	-0.2	-0.2	1.5	-0.5	-1.0	-0.1	-0.9	0.0	1.4	-0.7	0.4	-0.2
Trunk fat mass	0.8	3.3	12.0	-2.1	1.2	-1.4	-0.8	-1.5	-0.5	-1.9	-3.3	-1.8	-3.5	-2.9	0.0	-2.7	0.4	-2.2	0.5	-0.5	-2.1	-1.9	-1.0	-1.8	-1.1	-0.4
Pulse wave Arterial Stiffness index	0.8	0.9	4.6	-0.7	0.6	-0.6	-0.9	-0.1	0.2	-0.1	-0.7	-0.1	-0.4	-0.6	-1.8	1.6	-0.6	-0.4	-2.1	-2.1	-0.5	0.3	-0.1	-1.1	0.1	-0.6
Pulse wave peak to peak time	0.8	0.9	4.9	0.6	-0.5	0.5	0.9	-0.0	-0.1	-0.1	0.6	0.3	0.5	0.6	1.8	-1.6	0.7	0.4	2.2	2.1	0.3	-0.4	0.1	1.1	-0.2	0.6
Arm fat percentage (left)	0.8	3.0	19.9	-1.6	0.7	-1.2	-0.9	-0.9	-0.4	-0.9	-3.1	-2.3	-4.5	-3.0	-1.4	-1.7	-1.1	-2.5	-0.5	-0.8	-1.1	-1.1	-0.5	-1.7	-0.1	-0.0
Wears glasses or contact lenses	0.8	0.9	4.2	-0.1	-2.0	0.2	0.1	-0.7	0.7	-0.2	-0.7	-0.9	-2.0	-0.7	-0.9	0.2	-0.8	-1.2	-2.0	-1.0	0.1	-0.1	0.3	-1.0	0.3	-0.2
Risk taking	0.8	1.2	5.3	0.2	0.1	0.5	-0.9	-1.7	1.6	-1.9	-0.7	0.3	0.5	1.3	0.8	-1.9	2.3	-0.4	0.5	1.3	-0.9	-0.9	1.1	-0.1	-0.3	0.1
Pack years of smoking	0.8	1.2	6.7	0.4	1.7	1.1	-1.4	-0.4	2.6	-0.5	-0.1	0.9	0.1	0.1	-1.3	1.6	0.6	0.4	-2.4	-0.7	-0.1	0.9	1.4	-0.3	0.8	0.0
Ever used hormone-replacement therapy (HRT)	0.7	0.8	5.9	-0.6	-2.4	-0.8	-0.5	-1.1	0.6	-0.4	-1.4	-1.4	-0.4	-0.3	0.9	-0.9	0.3	-0.9	0.0	-0.7	-0.4	-0.7	-0.6	-0.5	-0.7	-1.3
Medication: Levothyroxine sodium	0.7	1.1	3.3	-0.2	-1.0	0.3	1.6	1.2	-1.1	1.5	0.9	1.2	0.9	-1.0	-1.1	1.1	-1.3	0.5	-1.3	-1.8	0.6	1.0	-0.9	0.1	0.1	-1.2
Hearing difficulty/problems with background noise	0.7	1.1	5.2	1.7	-0.5	0.9	-0.3	1.4	-0.3	1.3	2.3	0.8	0.6	0.6	0.5	0.3	0.4	0.5	0.3	1.2	1.8	0.9	0.7	1.6	0.7	0.0
Alcohol intake versus 10 years previously	0.7	1.0	5.0	0.5	0.8	-0.8	0.4	2.2	-1.5	1.8	0.5	-0.1	0.5	-1.0	0.2	0.4	-1.5	0.6	1.5	0.6	1.3	0.4	-0.7	1.2	-0.0	0.4
Number of live births	0.7	0.9	3.0	-1.4	-1.6	0.8	-0.0	-0.5	0.2	-0.7	-0.9	-1.2	-0.5	-1.6	0.5	-1.7	0.2	-0.9	0.0	-0.5	-0.8	-1.1	-1.2	-0.5	-1.0	-1.3
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	4.6	-0.8	-0.2	-0.3	-0.4	-1.4	0.6	-1.3	-0.2	-0.3	0.0	0.3	1.6	-2.1	2.0	-0.3	0.7	0.6	-1.0	-0.8	-0.2	-0.5	-0.6	-0.5
Depression (self-reported)	0.7	0.8	2.9	0.6	-1.0	0.2	0.1	-1.2	1.6	-0.9	-0.9	0.3	-1.3	0.7	-0.7	1.0	0.9	-0.5	-1.7	0.2	-0.1	0.2	1.6	-0.4	0.8	0.2
Medication: Lansoprazole	0.7	0.8	2.7	-0.1	-1.6	0.8	0.6	-1.4	1.5	-1.6	-1.0	0.5	-0.5	-0.2	-0.2	-0.9	1.4	0.6	-1.1	-0.0	-0.8	-0.2	1.1	-0.2	-0.1	0.7
Arm fat mass (right)	0.7	3.0	13.2	-1.8	1.8	-1.4	-0.7	-0.5	-0.9	-1.2	-3.0	-2.0	-3.6	-3.3	-0.1	-2.8	-0.3	-2.2	1.0	-0.0	-1.4	-1.6	-1.1	-1.2	-0.8	-0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.0	5.4	-0.3	-0.8	0.0	-0.0	-1.5	2.2	-1.4	-1.2	0.5	-0.4	0.4	-0.6	0.3	1.3	-0.2	-2.3	-1.0	-1.0	0.3	1.1	-0.8	0.3	-0.5
Medication for cholesterol, blood pressure or diabetes	0.7	1.1	3.6	-0.7	0.9	-1.9	-1.6	-0.4	-1.7	-0.4	-0.5	-0.6	0.2	-0.5	1.5	-1.8	0.4	-0.4	1.1	0.2	-0.7	-1.1	-1.4	0.1	-1.3	-1.2
Comparative body size at age 10	0.7	2.0	13.2	-0.6	2.5	-1.4	-1.4	0.2	-1.6	-0.4	-2.8	-1.1	-3.6	-1.6	-1.3	-0.3	-1.4	-1.5	-0.1	-0.1	0.0	-0.7	0.0	-0.4	0.2	1.1
Qualifications: College or University degree	0.7	2.1	12.2	-1.3	-3.5	-0.7	-2.2	-2.7	-0.0	-2.0	-1.8	-1.6	-1.1	0.8	0.5	-1.3	1.2	-1.0	0.1	0.1	-1.6	-1.0	0.3	-1.1	-0.3	0.4
Mouth/teeth dental problems: Loose teeth	0.7	0.8	3.3	-1.0	-1.2	-0.9	-0.1	-0.8	-0.1	-1.0	-0.6	-1.8	-0.1	0.0	0.5	-1.0	-0.1	-1.6	0.3	-0.0	-0.9	-1.4	-0.6	-1.3	-0.7	-0.0
Pulse rate, automated reading	0.7	2.2	8.9	-1.8	-1.2	-0.2	-1.0	-3.0	1.3	-2.3	-2.2	-1.6	-1.8	-1.2	-0.2	-2.1	0.9	-1.1	-1.1	-0.7	-2.2	-1.0	0.1	-1.8	-0.6	-0.4
Ever had bowel cancer screening	0.7	0.9	2.1	-0.5	-1.2	-0.2	-1.5	-1.3	1.4	-1.5	-0.9	-0.2	-0.6	-0.1	-0.1	-1.2	1.0	-1.2	-1.3	-0.4	-0.9	-0.7	0.7	-1.2	-0.1	-0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.5	6.6	1.2	0.4	1.0	0.7	1.2	-0.2	1.6	2.2	0.5	0.9	2.6	-0.3	2.0	-1.1	0.3	-0.0	0.7	1.8	1.0	0.7	1.1	1.1	0.8
Tinnitus: Yes, now most or all of the time	0.7	0.8	3.8	-0.1	-0.5	0.1	1.9	0.2	-1.5	0.5	0.9	0.6	0.8	-0.1	1.9	-0.4	0.6	0.0	1.1	-0.1	0.4	-0.8	-1.0	0.8	-1.4	-0.9
Average weekly beer plus cider intake	0.7	1.0	6.9	-0.6	-0.4	-1.3	-1.7	-0.4	-0.8	-0.3	0.5	-0.5	2.6	-0.2	1.8	-0.0	0.7	0.3	0.9	-0.1	-0.4	-0.9	-1.2	0.3	-1.4	-1.0
Heart disease (siblings)	0.7	0.8	2.3	-1.4	0.4	-0.3	0.5	-0.6	-1.3	-0.6	-0.9	-1.5	0.3	-0.8	0.6	-0.9	-0.1	-1.0	1.2	0.0	-0.9	-1.3	-1.2	-0.9	-1.1	-0.9
Impedance of whole body	0.7	3.8	16.5	-2.2	-3.6	-0.9	-0.7	-4.1	0.9	-2.9	-1.6	-1.5	0.5	0.5	-0.2	-1.1	1.5	-1.3	-2.1	-2.0	-3.0	-1.6	0.2	-2.9	-1.3	-0.9
Intelligence (Savage-Jansen 2018)	0.6	1.9	4.6	-1.9	-2.0	-0.1	-1.1	-2.1	-0.7	-2.2	-2.1	-0.7	-1.1	-0.4	-0.0	-0.8	0.8	-1.9	-0.8	-1.0	-2.1	-1.7	-0.6	-1.8	-1.2	-0.8
Ovarian Cancer	0.6	0.8	3.5	0.4	-1.1	0.6	0.9	0.7	-1.2	1.1	1.2	1.0	1.9	0.4	1.1	0.8	-0.1	0.9	1.0	0.2	0.7	0.1	-0.9	0.8	-0.5	-0.6
Prostate Cancer	0.6	0.8	2.5	-0.2	-1.5	1.3	1.4	0.9	0.2	1.2	0.9	1.6	0.6	-0.1	0.8	-0.0	-0.5	1.1	0.3	-0.3	0.7	0.6	-1.1	1.4	-0.2	-0.7
Crohns Disease (2012)	0.6	1.0	4.4	0.3	-2.1	0.4	1.3	-0.8	1.6	-0.8	-0.3	1.0	-0.9	0.6	-0.4	1.3	0.9	0.1	-0.8	0.7	-0.2	0.8	1.7	0.1	1.3	1.2
LDL Cholesterol	0.6	1.0	3.7	-0.0	0.8	0.3	1.8	1.0	-1.9	0.9	1.3	-0.0	1.8	0.3	1.4	0.5	-0.2	0.7	1.4	0.1	0.6	-0.2	-1.2	1.0	-0.8	-0.6
Cardiovascular Disease	0.6	1.9	5.8	1.5	-2.0	1.3	1.4	0.7	2.4	0.6	1.5	1.4	1.0	1.6	-0.1	0.7	0.9	1.3	0.4	1.8	1.3	1.4	1.9	1.1	1.6	1.6
Number of treatments/medications taken	0.6	1.1	4.6	-1.0	-2.1	1.5	1.3	-1.3	0.7	-1.1	-0.7	-0.4	1.0	-0.5	0.8	-1.1	1.1	-0.5	-0.1	-0.8	-1.1	-1.4	-0.5	-1.0	-1.4	-0.9
Average weekly spirits intake	0.6	0.8	3.1	1.1	1.4	1.1	-0.1	0.4	0.4	0.4	0.1	1.8	-0.1	0.7	-0.0	1.0	0.5	1.3	0.8	0.9	0.6	0.9	1.3	1.0	0.9	0.9
Ever had hysterectomy (womb removed)	0.6	0.7	3.4	-0.3	-1.0	-0.5	-0.0	0.9	-0.8	1.3	-0.2	-1.4	-0.3	-1.8	0.4	-0.7	-1.2	-0.6	0.4	-1.1	0.6	-0.3	-1.3	0.4	-0.7	-0.8
Severe depression (siblings)	0.6	0.7	4.9	-0.6	-0.5	-0.4	-2.2	0.2	0.1	-0.1	-0.9	0.1	-1.1	-0.7	-0.7	-0.0	-0.5	-0.9	-1.1	-1.2	-0.6	-0.2	-0.7	-0.6	-0.3	-1.4
Hand grip strength (right)	0.6	1.5	6.0	0.8	1.2	-0.2	1.1	1.7	-1.4	1.6	1.8	0.6	1.9	1.1	1.0	0.9	-0.6	1.3	2.5	1.3	1.2	0.4	-0.6	1.6	-0.1	0.5
Chronic bronchitis/emphysema (father)	0.6	0.7	3.9	0.4	-1.0	1.7	0.7	-0.5	2.0	-0.3	-0.5	0.4	-0.9	0.6	-0.7	-0.1	0.1	0.5	-1.8	-0.5	0.0	0.6	0.7	0.3	0.3	-0.2
Illnesses of siblings	0.6	0.8	3.1	-0.1	-0.0	-0.7	-0.5	1.1	-1.8	1.0	0.9	0.2	1.1	-0.8	-0.1	-0.5	-0.9	0.2	-0.1	-1.4	0.1	-0.4	-1.7	0.1	-1.2	-1.4
Noisy workplace	0.6	0.7	4.2	1.0	2.1	1.2	1.1	0.6	-0.1	0.2	1.2	0.5	1.2	0.7	0.9	-0.7	0.9	0.6	0.5	0.8	0.5	0.3	0.3	0.8	-0.0	-0.4
Mouth/teeth dental problems: Dentures	0.6	1.0	3.4	-1.7	-1.4	-0.8	-0.4	-0.4	-0.6	-0.1	-0.6	-0.9	0.3	-1.7	0.4	-1.2	-0.7	-0.2	-0.2	-1.6	-0.8	-0.6	-1.9	-0.5	-1.2	-1.6
Medication: Cholesterol lowering	0.6	0.9	3.8	-0.1	-0.7	1.6	1.1	-0.2	1.5	-0.1	-0.2	-0.0	-1.0	0.1	-1.8	1.2	-0.5	-0.7	-1.9	-0.7	0.1	0.6	1.0	-1.2	1.1	0.4
Hair/balding pattern: Pattern 4	0.6	1.5	6.6	-1.1	0.3	-1.3	-0.5	-1.2	1.2	-2.0	-2.6	-1.2	-1.3	-0.3	0.6	-2.4	1.4	-1.4	0.5	0.7	-1.5	-1.0	0.4	-0.8	-0.2	0.1
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	3.6	0.3	-1.0	0.6	-1.2	-0.9	1.1	-0.9	0.3	-0.4	-0.2	1.5	0.2	-0.3	1.0	-0.4	0.7	1.9	-0.2	-0.1	1.5	-0.4	1.0	1.4
Number of full brothers	0.6	0.8	2.5	0.6	-0.0	-1.0	-1.6	0.6	0.6	0.9	0.3	-0.8	-1.4	-0.7	-1.1	0.7	-1.5	-0.6	-1.2	-0.1	0.9	0.8	0.1	0.2	1.1	0.2
Migraine (self-reported)	0.6	0.8	3.4	0.2	-1.6	1.9	-0.2	-0.7	1.1	-0.3	0.3	1.3	1.2	0.8	1.1	0.0	1.4	1.1	0.0	0.1	-0.1	0.3	0.1	1.0	-0.3	-0.6
Overall health rating	0.6	1.3	5.8	-1.0	-0.6	0.4	0.6	-2.0	1.6	-2.2	-1.4	-0.2	-0.2	-0.6	1.1	-1.1	2.4	-0.1	-0.2	0.3	-1.6	-1.0	0.2	-0.4	-0.9	-0.8
Medication: Aspirin	0.6	0.8	3.8	-0.7	-0.4	2.0	-0.7	-1.4	0.5	-1.3	-0.9	-0.2	-0.4	-0.1	0.2	0.3	0.9	-1.5	-1.0	-0.6	-0.9	-1.1	-0.0	-1.1	-0.7	-1.0
Supplements: Vitamin C	0.6	0.7	3.3	-0.2	-1.8	-0.9	-1.5	-0.1	-0.2	0.2	-0.2	-1.7	0.7	-1.6	0.6	-0.6	-0.2	-0.5	0.8	-0.3	0.0	-0.8	-0.7	0.4	-1.1	-0.7
Arm fat mass (left)	0.6	2.5	13.4	-1.4	1.7	-1.4	-0.9	-0.4	-0.8	-0.9	-2.8	-1.7	-3.7	-3.0	-0.4	-2.2	-0.5	-2.0	0.8	-0.1	-1.1	-1.4	-0.9	-1.1	-0.5	-0.1
Commuting to job workplace: Public transport	0.6	0.7	5.0	0.1	-0.9	-1.0	0.7	0.0	-2.2	0.6	-0.4	-1.0	-0.0	-1.0	0.7	-0.3	-0.4	-0.7	0.7	-0.6	0.1	-0.8	-1.1	0.2	-0.9	-0.8
Alcohol drinker status: Never	0.6	0.7	5.5	0.2	-0.5	0.3	-0.5	-0.3	-0.0	-0.6	0.5	0.4	1.0	1.0	2.4	0.3	1.5	0.7	1.4	1.4	-0.2	-0.1	-0.0	0.6	-0.0	0.2
Bipolar Disorder (2018)	0.5	0.8	3.4	-0.9	0.8	-1.2	-0.4	-0.6	-1.8	-0.7	-1.0	-0.1	-0.0	-0.1	1.2	-1.3	0.7	-0.9	0.4	-0.1	-0.7	-1.2	-1.0	-0.3	-1.2	-1.6
Depression (Nagel 2018)	0.5	0.8	5.6	0.5	0.9	-0.5	-1.0	-0.0	-0.1	-0.1	-0.9	0.1	-2.4	-0.4	-1.3	1.1	-0.8	-1.2	-2.0	-0.5	0.3	-0.1	0.2	-0.6	0.3	-0.2
Schizophrenia vs Biploar Disorder	0.5	0.7	3.2	0.7	0.1	0.7	-0.6	0.3	1.0	-0.3	0.7	0.9	0.9	0.5	1.1	-0.9	1.1	0.7	1.8	1.5	-0.0	-0.3	0.4	0.5	-0.1	1.1
Crohns Disease (2017)	0.5	1.1	4.7	0.2	-1.8	1.1	1.9	-1.2	2.2	-1.1	0.3	0.4	0.0	0.8	0.8	-0.0	1.7	0.3	0.1	1.2	-0.5	0.5	1.1	0.0	0.9	0.8
Body Mass Index (BMI) (2010)	0.5	0.8	6.2	0.1	1.6	0.6	0.4	0.8	-0.7	0.7	-0.7	0.0	-2.5	-1.7	-0.9	0.2	-1.0	0.1	-0.2	-0.6	0.4	0.3	-0.4	-0.1	0.1	0.1
Fasting Glucose	0.5	0.6	2.6	0.3	0.0	0.1	0.7	1.3	-1.1	1.6	0.3	-0.3	-0.3	-1.2	-0.1	0.1	-1.1	-0.5	0.1	-1.0	0.5	0.4	-1.2	0.7	-0.3	-1.2
Schizophrenia (2014)	0.5	1.0	4.6	0.2	0.5	-0.1	0.2	-0.5	0.2	-1.0	-0.4	0.4	0.4	1.5	2.1	-0.6	2.1	0.0	2.0	2.1	-0.3	-0.5	0.8	0.8	0.0	0.7
BMI	0.5	2.9	18.2	-1.1	2.4	-1.1	0.1	0.1	-1.0	-0.5	-2.7	-1.7	-4.3	-3.6	-1.3	-1.9	-1.2	-2.0	0.5	-0.2	-0.7	-1.1	-0.8	-1.2	-0.2	0.3
Hand grip strength (left)	0.5	1.3	3.4	1.3	1.0	0.3	0.5	1.6	-0.8	1.5	1.6	0.7	1.3	1.3	0.7	0.8	-0.6	1.3	1.8	1.5	1.5	0.7	0.1	1.6	0.5	1.0
Frequency of depressed mood in last 2 weeks	0.5	0.7	3.5	0.1	0.7	-0.6	-1.1	-0.2	0.3	-0.4	-0.6	-0.3	-1.9	-0.5	-1.5	1.0	-0.7	-1.1	-1.9	-0.4	0.1	-0.2	0.6	-0.8	0.3	0.4
Average weekly fortified wine intake	0.5	0.6	3.0	-0.4	-1.7	0.1	-0.9	0.0	-0.5	0.5	-0.4	-0.8	-0.4	-1.6	-0.9	-0.1	-1.4	-0.1	-1.1	-0.9	0.1	0.2	-0.7	-0.5	-0.0	-0.4
Supplements: Glucosamine	0.5	0.6	2.0	-0.8	-0.7	-0.0	0.0	-0.7	-0.7	-0.5	-1.4	-0.0	-1.3	-0.9	-0.2	-0.7	-0.6	-1.1	0.2	-0.4	-0.5	-1.3	-0.9	-0.7	-1.1	-0.4
High blood pressure (mother)	0.5	0.7	5.8	0.1	-2.4	0.4	-0.0	-1.1	0.3	-1.2	-0.6	0.3	-0.2	0.1	1.0	-0.6	1.5	0.7	0.4	1.1	-0.4	-0.0	0.8	0.5	0.0	0.5
Had menopause	0.5	0.6	4.0	-0.1	-1.7	0.0	-0.0	-0.5	1.2	-0.3	-1.7	-0.1	-2.0	0.0	-0.6	0.6	-0.4	-0.7	-1.0	-0.6	-0.0	0.3	0.6	0.0	0.6	-0.0
Heart attack	0.5	0.7	2.4	-0.1	0.9	1.5	1.1	1.3	-0.9	1.1	0.9	0.1	0.9	0.2	-0.2	1.4	-0.9	-0.1	-0.1	-0.2	0.8	0.4	-0.7	0.7	0.0	-1.1
Pain all over the body in last month	0.5	0.5	8.3	0.6	2.9	1.0	0.2	0.4	-0.2	-0.0	0.2	0.8	-0.8	-0.4	-0.3	0.1	0.6	0.1	0.2	0.6	0.1	0.2	0.4	0.4	0.3	0.1
Medication: Simvastatin	0.5	0.7	3.2	-1.0	-1.2	1.8	0.3	-0.3	0.5	-0.2	-0.7	-0.7	-1.0	-0.8	-1.2	0.5	-0.8	-0.9	-1.1	-1.2	-0.5	-0.3	-0.3	-1.0	-0.1	-0.5
Impedance of arm (right)	0.5	2.4	11.5	-2.1	-2.3	-0.5	-0.7	-3.4	0.9	-2.4	-1.5	-1.4	-0.1	0.6	-0.4	-1.0	1.4	-0.9	-1.5	-1.3	-2.6	-1.0	0.5	-2.4	-0.6	-0.2
Trunk fat-free mass	0.5	2.6	27.1	0.7	5.2	0.0	0.2	2.4	-0.7	0.7	0.4	2.1	-0.3	-0.7	0.9	-0.7	0.4	1.4	2.7	1.9	0.8	0.4	-0.4	1.9	0.2	0.9
Hip circumference	0.5	2.0	8.4	-1.0	2.9	-0.9	0.1	1.5	-2.5	0.5	-0.8	-0.1	-1.0	-2.8	1.0	-1.3	-0.5	-0.4	2.3	0.0	-0.2	-0.9	-2.3	0.4	-1.2	-0.8
Length of working week for main job	0.5	0.5	1.9	0.3	0.7	0.1	0.6	-0.1	-0.7	-0.0	0.8	-0.4	1.4	0.6	1.2	-0.5	0.4	-1.3	0.6	0.2	0.2	-1.1	-0.4	0.0	-1.0	-0.9
Pulse wave reflection index	0.5	0.6	3.3	-0.5	-0.1	-1.5	-0.2	0.6	-1.8	0.7	-0.1	0.3	0.6	-1.0	-0.4	0.5	-0.7	0.2	-0.7	-1.6	0.1	0.0	-1.1	0.2	-0.7	-1.0
Blood clot in the leg (DVT)	0.5	0.7	2.6	-0.5	-1.6	-0.5	-0.9	-1.1	0.8	-0.8	-1.0	-1.1	-1.3	-0.9	-0.6	-0.8	-0.4	-0.9	-1.2	-0.2	-0.5	-0.4	-0.1	-0.9	0.0	-0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.5	2.7	0.4	-0.5	0.0	0.2	0.1	0.5	0.5	-0.5	0.1	-1.0	0.1	-1.6	0.4	-1.5	-0.8	-1.5	-0.8	0.5	0.4	0.6	-0.5	0.5	-0.1
Alcohol intake frequency.	0.5	1.1	6.1	-0.3	-0.3	0.1	-0.4	-0.3	0.2	-0.6	-0.2	0.7	0.8	-0.4	1.9	-2.5	2.1	0.9	2.1	1.3	-0.5	-0.3	-0.2	1.0	-0.5	-0.4
Comparative height size at age 10	0.5	3.0	18.7	-2.1	4.3	-2.0	-0.4	-0.1	-2.5	-1.1	-1.7	0.6	-0.6	-2.2	0.1	-2.2	0.2	-0.8	0.8	-1.4	-2.0	-1.6	-2.2	-0.9	-2.0	-1.1
Knee pain experienced in last month	0.5	0.8	2.6	0.2	-1.2	1.6	1.5	0.5	0.2	0.6	1.0	0.1	-0.4	0.7	0.2	-0.5	0.6	1.2	1.4	1.6	0.6	0.6	0.4	0.9	0.5	1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	2.4	-0.9	0.5	-0.3	0.7	-0.2	-0.8	-0.5	-1.3	-0.3	-0.3	-1.5	0.4	-0.7	0.1	-0.4	-0.3	-1.1	-0.9	-0.7	-1.2	-0.2	-1.1	-1.1
Leg fat-free mass (right)	0.5	2.6	20.0	1.4	4.5	0.8	0.3	2.6	0.3	1.1	0.7	2.5	-0.4	0.2	0.4	-0.0	0.5	1.5	2.2	2.1	1.2	1.1	0.4	2.1	1.0	1.1
Qualifications: nursing, teaching	0.5	0.7	3.3	-0.0	-0.6	1.6	-0.9	-0.8	1.4	-1.1	-0.5	0.6	-1.0	1.8	-0.1	0.1	1.2	-0.5	-0.8	0.3	-0.5	0.0	1.1	-0.0	0.5	0.5
Mouth/teeth dental problems: Mouth ulcers	0.5	0.9	2.5	-0.4	-0.5	-0.7	-1.3	-1.6	0.8	-1.4	-1.0	-0.1	-0.1	0.5	1.0	-0.8	1.4	-1.1	-0.2	-0.1	-1.0	-1.3	-0.2	-0.6	-1.1	-1.2
Leg predicted mass (right)	0.5	2.5	20.0	1.4	4.5	0.8	0.2	2.5	0.3	1.0	0.7	2.5	-0.4	0.2	0.5	-0.1	0.6	1.5	2.2	2.0	1.2	1.1	0.3	2.1	0.9	1.0
Number of self-reported non-cancer illnesses	0.5	0.9	7.6	-1.1	-2.8	0.6	-0.3	-1.3	1.4	-1.2	-0.9	0.1	-0.2	-0.0	0.1	-0.2	1.1	-0.6	-0.9	-0.7	-1.1	-0.5	0.3	-1.1	-0.2	-0.4
Financial situation satisfaction	0.5	0.6	3.7	0.2	1.2	-0.2	-1.9	-0.3	1.4	-0.7	-1.1	-0.5	-1.3	-0.8	-0.4	-0.4	0.2	-0.7	-1.1	-0.4	-0.4	-0.2	0.3	-0.3	0.1	0.0
Pain type(s) experienced in last month: Hip pain	0.5	0.6	2.9	-0.1	-0.2	0.2	0.3	0.4	-0.2	-0.0	-0.9	-0.8	-1.7	-1.3	-1.5	0.2	-1.1	-1.2	-1.3	-0.7	-0.1	0.2	0.1	-0.7	0.7	0.0
Cholesterol lowering medication	0.5	0.8	2.9	-0.9	-1.7	-0.7	-1.1	-0.0	-1.3	0.2	-1.1	-1.2	-0.5	-1.1	0.5	-0.5	-0.7	-1.1	0.2	-0.3	-0.0	-0.9	-1.1	0.0	-0.9	-1.4
Pain experienced in last month	0.5	0.8	4.2	-0.5	1.4	-2.0	-0.9	-0.0	-1.0	-0.3	-0.8	-0.9	-0.2	-0.8	-0.8	0.4	-1.2	-1.0	-1.1	-1.1	-0.4	-0.7	-0.7	-1.0	-0.6	-0.0
Heart attack/myocardial infarction (self-reported)	0.5	0.6	2.3	-0.0	0.7	1.5	0.9	1.1	-0.7	1.0	1.0	0.2	1.0	0.4	-0.0	1.2	-0.7	0.0	-0.0	0.1	0.8	0.5	-0.6	0.8	0.1	-0.9
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	2.7	-0.5	-1.6	-0.4	-0.8	-1.3	0.9	-0.9	-0.8	-1.0	-1.0	-0.5	-0.4	-1.0	-0.1	-0.7	-1.0	-0.1	-0.6	-0.5	-0.1	-0.8	-0.2	-0.4
Alcohol drinker status: Previous	0.5	0.6	3.6	-0.6	-0.5	-0.4	-0.9	-1.0	0.8	-1.0	-0.7	-0.6	-0.4	0.1	-0.3	-1.9	0.7	-0.8	-0.5	-0.4	-0.9	-0.7	0.0	-0.6	-0.5	-0.7
Depressed Affect (Nagel 2018)	0.4	0.8	3.4	0.0	0.7	-0.7	-0.0	-0.5	1.0	-0.7	-0.8	0.3	-1.4	-0.9	-0.6	-1.0	-0.1	-1.6	-1.8	-0.8	-0.3	-0.8	-0.4	-0.7	-0.7	-1.3
Schizophrenia (2018)	0.4	0.7	3.7	0.2	0.0	0.2	0.4	-0.7	0.5	-1.0	-0.4	-0.3	0.1	1.1	1.4	-0.7	1.6	-0.0	1.5	1.9	-0.3	-0.3	1.0	0.6	0.3	0.9
Blood Eosinophil Count	0.4	3.4	11.6	-1.5	1.8	-1.8	0.4	1.3	-3.3	1.2	-0.9	-1.4	-1.5	-3.4	-1.1	-1.2	-2.9	-2.2	-0.4	-2.2	0.0	-1.3	-2.9	-1.3	-1.6	-2.0
Lung FVC	0.4	2.2	8.9	1.1	-0.7	1.0	-0.8	1.5	-0.7	2.0	3.0	1.5	2.5	1.8	-0.0	2.8	-1.5	1.2	-0.4	-0.1	1.8	1.3	-0.3	1.4	0.5	-0.1
Medication for hormone replacement therapy	0.4	0.5	1.5	-0.2	-1.0	-0.6	-1.2	-0.5	0.0	-0.5	-0.3	0.3	0.4	0.0	0.4	-0.2	0.6	-0.9	-0.8	-1.2	-0.6	-1.0	-0.6	-0.3	-1.1	-1.0
Medication: Co-codamol	0.4	0.5	5.1	-0.7	-2.2	-0.0	-0.5	0.0	-0.7	0.0	-0.6	-0.5	0.2	-1.3	0.0	-0.4	0.1	0.3	0.3	-0.7	-0.4	-0.4	-0.8	0.3	-0.7	-0.5
Medication: Metformin	0.4	0.6	2.3	-0.7	1.5	0.2	-1.1	-0.7	0.4	-0.6	-1.2	-0.4	-1.5	-1.3	-0.4	-0.3	0.2	0.4	0.5	0.1	-0.6	-0.1	0.5	-0.2	-0.0	1.1
Leg fat-free mass (left)	0.4	2.2	19.6	1.0	4.4	0.6	0.1	2.3	0.1	0.7	0.2	2.2	-0.9	-0.1	0.4	-0.2	0.6	1.2	2.3	2.1	0.8	0.8	0.3	1.8	0.9	1.3
Relative age voice broke	0.4	0.5	3.5	0.2	-1.6	-0.9	-0.2	-0.2	0.3	0.4	0.8	0.4	1.9	0.7	1.1	0.1	0.6	0.9	0.7	0.2	0.4	-0.1	-0.3	0.6	-0.6	-0.5
Body mass index (BMI)	0.4	1.7	10.2	-0.8	1.5	-1.1	-0.5	0.4	-1.0	-0.1	-2.0	-1.5	-3.2	-2.9	-0.1	-1.6	-0.9	-1.6	1.1	0.3	-0.2	-0.8	-1.0	-0.4	-0.2	-0.1
Leg predicted mass (left)	0.4	2.2	20.1	1.0	4.5	0.5	0.1	2.2	0.2	0.6	0.2	2.2	-0.8	-0.1	0.4	-0.3	0.7	1.2	2.3	2.1	0.8	0.8	0.4	1.7	0.9	1.3
Ever unenthusiastic/disinterested for a whole week	0.4	0.4	2.5	0.2	0.7	-0.2	0.2	-0.4	1.0	-0.3	-0.8	1.2	-0.5	0.4	-0.5	0.7	0.2	-0.3	-1.6	-1.0	-0.2	0.2	0.5	-0.1	0.0	-1.0
Pulse rate	0.4	0.6	2.8	0.1	-0.6	1.2	-0.3	-1.0	1.7	-0.7	0.3	-0.3	0.6	0.8	1.2	-1.2	1.4	0.8	0.4	0.7	-0.6	0.1	0.3	0.1	-0.1	0.0
Prospective memory result	0.4	0.5	1.5	1.0	1.2	-0.7	-0.3	0.4	0.8	0.3	0.9	0.8	0.9	0.2	0.4	0.6	0.3	1.2	0.6	0.9	0.6	0.5	0.2	1.1	0.2	0.4
Lung cancer (father)	0.4	0.4	3.2	0.1	-0.1	0.1	0.2	0.0	-0.8	0.1	0.6	-0.0	0.6	0.2	0.9	0.2	0.5	1.8	1.4	0.3	-0.0	-0.0	-0.2	1.2	-0.7	0.7
Impedance of arm (left)	0.4	1.6	6.6	-1.2	-2.1	-0.0	-0.5	-2.6	1.1	-1.6	-0.7	-0.5	0.0	1.3	-1.2	0.1	0.8	-0.7	-2.2	-1.5	-1.8	-0.3	0.9	-2.1	0.0	-0.0
Trunk predicted mass	0.4	2.5	26.6	0.7	5.2	-0.1	0.1	2.4	-0.7	0.6	0.2	2.0	-0.4	-0.7	0.9	-0.8	0.4	1.2	2.6	1.9	0.7	0.4	-0.4	1.9	0.2	0.9
Ever highly irritable/argumentative for 2 days	0.4	0.4	2.4	-0.5	-1.1	-0.7	-1.6	-0.1	-0.5	0.2	-0.4	-0.6	-0.6	-1.1	-0.4	-0.4	-0.2	0.0	-0.3	-0.8	0.0	-0.2	-0.6	0.3	-0.8	-1.0
Medication: Paracetamol	0.4	0.6	2.0	0.9	0.3	1.4	0.5	0.0	0.8	0.3	0.6	1.0	0.8	0.8	1.3	0.1	0.9	1.3	0.6	0.8	0.7	0.5	0.4	1.3	0.0	0.1
Birth weight	0.4	0.8	3.0	-0.1	-1.5	0.3	0.7	-0.8	0.2	-0.9	0.4	0.3	0.6	1.0	1.6	-1.6	1.7	0.2	1.3	1.2	-0.5	-0.7	0.2	0.3	-0.5	0.1
Exposure to tobacco smoke outside home	0.4	0.5	1.7	-0.3	0.6	-0.7	-0.7	-0.4	-0.2	-1.0	-0.8	-0.6	-0.7	0.1	-0.1	-1.3	0.3	-1.3	-0.3	0.0	-0.7	-1.2	-0.1	-0.7	-0.7	-0.4
Medication: Seretide 50 evohaler	0.4	0.4	3.2	0.3	1.8	-0.2	-0.7	0.4	0.2	0.5	-0.1	0.3	-0.1	-0.6	0.4	-0.3	-0.3	0.8	0.7	1.1	0.5	0.8	0.4	0.8	0.7	0.8
Number of full sisters	0.4	0.5	2.2	0.9	-0.3	0.3	1.0	0.9	-0.1	0.5	0.3	-1.0	0.8	-0.8	1.0	-0.9	0.9	-0.2	0.7	0.5	0.8	0.0	0.0	1.5	-0.1	-0.7
Whole body fat-free mass	0.4	2.4	24.4	0.9	4.9	0.2	0.2	2.4	-0.4	0.7	0.3	2.2	-0.5	-0.5	0.7	-0.5	0.5	1.3	2.5	1.9	0.8	0.6	-0.1	1.9	0.5	0.9
Medication for cholesterol	0.4	0.6	5.0	-0.8	2.2	-0.3	0.6	-0.6	-0.4	-0.6	-0.8	-0.4	-0.6	-0.7	-0.7	0.1	-0.6	-0.7	-0.9	-1.1	-0.9	-0.3	-0.5	-1.1	-0.3	-0.3
Whole body water mass	0.4	2.3	23.9	0.8	4.9	0.2	0.2	2.3	-0.4	0.6	0.1	2.1	-0.6	-0.6	0.6	-0.6	0.4	1.1	2.5	1.9	0.8	0.5	-0.1	1.8	0.4	1.0
Miserableness	0.4	0.6	2.5	-0.3	0.6	-0.5	-0.2	-0.7	0.7	-0.7	-0.9	-0.3	-0.8	-0.8	-0.9	-0.6	0.2	-1.4	-1.6	-0.9	-0.6	-0.8	-0.1	-1.0	-0.6	-1.1
Hearing aid user	0.4	0.5	2.0	-0.4	-0.2	-0.2	0.1	0.9	-0.2	0.9	0.0	-1.3	0.1	-1.4	-0.4	-0.3	-0.9	-0.5	-0.2	-0.9	0.5	-0.1	-1.1	0.0	-0.4	-1.4
High cholesterol (Self-reported)	0.4	0.8	3.2	-1.1	-1.8	-0.5	-0.3	0.1	-0.8	0.6	-0.4	-0.8	-0.3	-1.8	-0.8	0.2	-1.2	-0.5	-0.9	-1.5	-0.1	-0.1	-1.0	-0.7	-0.4	-1.0
Basal metabolic rate	0.4	1.9	21.3	0.4	4.6	-0.1	0.1	1.9	-0.5	0.3	-0.2	1.6	-0.9	-1.0	0.8	-1.1	0.5	0.7	2.5	1.7	0.4	0.1	-0.4	1.4	0.1	0.7
Arm fat-free mass (left)	0.4	1.9	15.4	-0.1	3.9	-0.6	-0.1	1.4	-0.9	-0.1	-0.7	0.8	-0.8	-1.4	1.5	-1.9	0.7	0.2	2.8	1.6	-0.0	-0.6	-1.0	1.2	-0.6	0.1
Myopia	0.4	0.6	2.0	-0.6	-1.1	0.2	0.3	-1.4	0.7	-1.4	-0.9	-0.6	-0.2	0.5	0.5	-0.6	0.5	-0.9	-0.3	0.1	-0.9	-1.0	0.2	-1.0	-0.6	-0.0
Bipolar Disorder or Schizophrenia	0.3	0.8	3.4	-0.4	0.5	-0.4	0.2	-0.9	-0.7	-1.2	-1.0	-0.3	0.0	0.8	1.8	-1.3	1.7	-0.6	1.4	1.4	-0.6	-1.0	0.1	0.3	-0.5	-0.3
Alzheimer’s Disease (in father)	0.3	0.3	2.1	-0.3	0.3	-0.3	-1.5	-0.1	0.7	-0.3	-0.8	-0.4	-0.9	-0.2	-0.0	0.5	-0.0	-1.0	-0.6	-0.0	-0.2	0.2	0.2	0.1	0.5	-0.2
Breast Cancer	0.3	0.7	2.7	-0.0	0.2	0.3	-0.9	-0.2	0.5	-0.5	-0.8	-0.1	-1.2	-0.1	-1.6	1.0	-0.7	-1.4	-1.5	-0.3	-0.3	-0.1	0.9	-1.5	0.7	0.7
Age at First Birth	0.3	0.5	1.2	0.9	0.7	0.6	-0.2	0.7	0.0	0.6	-0.2	0.5	-0.6	1.1	-1.0	0.8	-0.6	0.5	-0.1	0.6	0.8	0.9	1.1	0.3	1.1	1.1
Primary Biliary Cirrhosis	0.3	0.4	1.6	0.6	1.2	0.9	0.3	0.7	0.8	0.8	-0.1	0.4	-0.6	0.4	-0.2	0.9	-0.6	-0.4	-0.7	-0.2	0.9	0.7	0.6	0.9	0.7	-0.0
Type 2 Diabetes (T2D) (2012)	0.3	0.3	1.5	0.5	0.9	1.0	0.3	0.5	0.7	-0.1	0.7	1.2	-0.2	1.0	0.2	0.1	0.7	-0.2	-0.0	0.8	-0.0	0.1	0.5	0.4	0.4	0.1
Height	0.3	5.1	26.1	-0.5	4.7	1.0	0.7	-1.5	2.6	-3.5	-1.6	3.1	0.6	2.4	1.8	-2.7	5.1	1.0	1.7	1.8	-2.6	-0.9	1.0	0.6	-0.7	0.2
Hypothyroidism (self reported)	0.3	0.7	4.0	-0.9	0.2	-0.4	2.0	0.3	-1.2	0.4	0.4	-0.1	0.7	-0.6	-0.3	0.8	-0.7	-0.1	-0.8	-1.7	-0.4	-0.1	-0.9	-0.9	-0.6	-0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.5	2.3	0.7	0.9	0.5	-0.6	0.7	0.5	0.6	0.3	0.8	-0.6	0.7	-0.5	1.5	-0.2	0.5	-1.1	-0.1	0.7	0.7	0.3	0.6	0.5	0.2
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	1.5	-0.5	0.2	0.1	0.7	-0.1	-0.3	0.0	-0.1	-0.1	0.0	-0.4	1.2	-0.9	0.4	-0.3	0.7	-0.5	-0.4	-0.6	-0.8	-0.1	-0.9	-0.6
Serious illness, injury or assault to yourself	0.3	0.4	3.6	0.1	1.9	-0.5	-0.0	0.1	0.1	0.3	-0.3	0.6	-0.1	0.6	-0.7	1.3	-0.6	-0.1	-0.5	-0.6	0.3	0.1	-0.0	0.3	-0.1	-0.2
Forced vital capacity (FVC)	0.3	1.3	6.0	0.7	1.0	0.6	-0.2	0.9	-0.2	0.6	1.9	2.1	2.4	2.1	1.1	1.0	0.4	1.2	0.8	0.9	0.7	0.5	-0.2	1.5	-0.1	0.1
Qualifications: None of the above	0.3	0.6	2.2	1.1	0.8	0.4	-0.0	1.5	0.8	1.0	1.1	0.4	0.8	-0.0	0.6	0.7	0.1	0.1	0.5	0.6	1.2	0.5	0.1	1.2	0.2	-0.4
Financial difficulties in last 2 years	0.3	0.3	1.3	1.1	0.7	0.3	-0.2	0.9	0.5	0.5	0.5	0.4	0.3	0.8	0.5	0.8	0.0	0.4	0.7	0.9	0.9	0.2	0.2	0.6	0.2	0.1
Weight	0.3	1.6	10.3	-0.8	3.2	-0.7	-0.5	0.5	-0.7	-0.7	-1.8	-0.1	-2.3	-2.2	0.6	-2.0	0.5	-0.7	1.8	0.8	-0.8	-0.9	-0.8	0.1	-0.5	0.1
Standing height	0.3	2.6	17.6	0.0	4.2	0.7	0.2	0.1	0.7	-1.4	0.0	3.2	1.6	1.4	1.5	-1.2	3.0	1.7	2.0	1.4	-1.3	-0.2	0.3	1.0	-0.6	0.7
Breastfed as a baby	0.3	0.4	3.3	0.5	1.0	0.2	-1.8	-0.1	-0.6	-0.2	0.2	1.1	0.3	0.9	-0.2	-0.2	0.4	-0.5	-0.5	0.1	0.3	-0.5	0.1	0.5	-0.3	-0.1
Birth weight of first child	0.3	0.5	1.9	0.1	-0.8	0.1	-0.6	-0.1	0.7	-0.6	-0.7	-0.3	-1.4	0.8	0.5	-0.6	0.7	-0.4	0.4	1.2	0.0	0.2	1.4	0.2	1.0	1.3
Hypothyroidism/myxoedema (self-reported)	0.3	0.5	2.7	-0.3	-0.2	0.3	1.6	0.6	-0.7	0.6	0.7	1.1	1.2	-0.3	-0.1	0.3	-0.2	0.4	-0.7	-1.3	-0.1	0.3	-0.9	-0.0	-0.4	-1.2
Arm fat-free mass (right)	0.3	1.5	15.8	0.7	4.0	-0.2	0.1	1.9	-0.3	0.4	-0.4	1.6	-0.7	-0.9	0.8	-0.9	0.4	0.6	2.1	1.4	0.5	-0.0	-0.5	1.5	-0.1	0.3
Arm predicted mass (right)	0.3	1.5	15.1	0.3	3.9	-0.2	0.3	1.5	-0.5	-0.1	-0.5	1.6	-0.5	-0.8	1.1	-1.2	0.9	0.4	2.3	1.3	0.1	-0.4	-0.7	1.2	-0.4	0.1
Family relationship satisfaction	0.3	0.4	1.7	0.8	0.2	0.4	-0.2	0.5	0.3	0.3	0.3	-0.3	-0.4	1.3	1.2	-0.7	0.4	-0.5	0.4	1.1	0.8	-0.1	0.3	0.7	0.1	-0.3
Leg pain on walking	0.3	0.3	1.3	-0.3	0.9	0.3	1.1	-0.5	-0.1	-0.9	-0.7	0.5	-1.1	-0.2	-0.7	0.1	0.6	0.1	-0.8	-0.5	-0.7	0.0	0.5	-0.1	0.0	0.1
Smoking status: Previous	0.3	0.4	1.6	-0.5	-0.1	0.9	0.9	0.2	-0.6	0.4	0.3	-0.3	0.7	-1.2	-0.3	-0.3	-0.6	-0.6	-0.3	-1.3	-0.1	-0.5	-0.6	-0.4	-0.8	-0.7
Mineral and other dietary supplements	0.3	0.3	1.8	0.8	0.3	0.9	0.4	0.1	0.7	0.1	0.7	0.1	0.3	1.4	0.3	-0.3	1.0	0.2	-0.1	0.5	0.3	0.6	0.7	0.5	0.6	0.2
Ever taken oral contraceptive pill	0.3	0.3	1.0	0.1	0.6	0.1	0.6	0.4	0.3	0.5	0.9	0.9	0.8	0.0	0.9	0.4	-0.0	-0.1	-0.5	-0.3	0.4	0.5	-0.6	0.1	0.2	-1.0
Medication: Paracetamol	0.3	0.5	3.1	-0.1	0.2	0.6	-0.2	-0.9	0.8	-0.8	-0.6	-0.2	0.1	0.1	1.8	-1.1	1.3	0.5	0.9	1.0	-0.3	-0.4	0.2	0.6	-0.4	0.1
Medication: Atorvastatin	0.3	0.4	1.1	0.5	0.6	-0.6	-0.3	0.9	-1.0	0.7	0.1	-1.0	-0.6	-0.6	0.3	-0.3	-0.4	-0.9	0.3	0.7	1.0	-0.2	-0.3	0.6	0.1	-0.4
Commuting to job workplace: Cycle	0.3	0.4	1.6	0.4	-1.3	0.2	-0.4	0.8	-0.5	0.8	1.1	-0.6	0.4	-0.1	-1.1	-0.1	-0.6	-1.1	-1.0	-0.3	0.7	-0.2	-0.2	-0.2	-0.1	-0.3
Basal cell carcinoma (self-reported)	0.3	0.3	2.0	-0.2	-0.0	-0.2	-1.4	-0.7	0.0	-0.3	-0.6	0.8	-0.2	0.1	0.6	-0.4	0.5	-0.2	-0.0	-0.8	-0.5	-0.4	-0.5	0.2	-0.7	-1.0
Arm predicted mass (left)	0.3	1.7	14.4	0.1	3.8	-0.5	0.1	1.5	-0.8	0.1	-0.6	1.1	-0.8	-1.4	1.3	-1.6	0.6	0.5	2.6	1.5	0.1	-0.3	-0.8	1.3	-0.4	0.2
Rheumatoid Arthritis	0.2	0.3	1.9	-0.1	1.4	0.5	-0.3	-0.0	0.7	-0.7	-0.2	0.4	0.3	0.5	0.5	0.1	0.9	0.1	1.0	0.8	-0.4	-0.5	0.4	0.1	-0.2	0.7
Triglycerides	0.2	0.3	0.9	0.1	0.7	0.4	0.3	0.7	-0.2	0.3	0.9	0.4	0.9	0.5	0.7	0.6	0.3	0.4	0.8	0.9	0.3	0.4	0.3	0.6	0.3	0.4
Chronotype (morning person)	0.2	0.5	2.9	0.4	0.9	0.4	0.0	0.6	0.2	0.3	0.3	0.2	-0.0	1.4	0.9	-0.6	0.6	0.0	1.7	1.0	0.5	-0.1	0.4	0.5	0.1	0.8
Tanning	0.2	2.2	9.0	1.2	-0.8	-0.8	-0.6	2.2	-1.8	3.0	2.3	-0.6	1.1	-1.1	-0.9	1.0	-3.0	0.8	-0.4	-1.4	2.1	0.7	-1.7	0.9	-0.4	-0.9
Past tobacco smoking	0.2	0.4	1.7	-0.1	-0.4	-1.3	-1.1	-0.3	-0.8	-0.6	-1.0	-0.7	-1.3	-0.2	0.2	-0.6	-0.0	-0.6	0.4	0.9	-0.2	-0.6	-0.2	0.1	-0.1	0.1
Qualifications: O levels/GCSEs or equivalent	0.2	0.4	1.9	-0.8	-0.6	-0.2	-0.8	-0.4	-1.4	-0.6	-0.3	0.2	0.4	-0.0	0.3	-0.5	0.3	1.0	1.0	0.3	-0.8	-0.3	-0.6	0.0	-0.6	0.3
Chronic bronchitis/emphysema (mother)	0.2	0.3	2.1	-0.7	-0.6	0.6	-1.4	-0.6	0.1	-0.3	0.0	-0.9	0.1	-0.0	0.3	-0.5	-0.0	0.4	0.4	-0.1	-0.4	-0.3	-0.2	-0.3	-0.3	0.6
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	1.5	-0.3	-0.1	0.1	1.0	0.3	-0.7	0.0	0.2	-0.2	0.6	-0.3	0.4	-1.2	0.2	0.5	0.7	0.2	-0.2	-0.1	-0.5	0.4	-0.3	-0.4
Mood swings	0.2	0.3	2.2	0.4	0.7	0.4	0.3	-0.7	1.5	-0.7	-0.6	0.7	-0.8	0.2	-0.4	-0.4	0.8	0.2	-0.9	0.2	-0.0	-0.1	0.5	0.3	-0.2	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	1.3	-0.0	-0.1	-0.6	-1.2	-0.2	-0.1	-0.6	-0.6	-1.2	-0.3	0.1	0.3	0.4	0.2	-0.2	0.4	0.5	-0.2	-0.4	0.2	-0.1	-0.1	0.3
Mother’s age at death	0.2	0.3	1.0	-0.1	-0.7	0.2	0.9	-0.2	0.3	-0.2	-1.0	-0.1	-0.9	-0.5	-0.5	0.8	-0.1	0.5	-0.4	-0.3	-0.1	0.6	0.4	0.2	0.4	0.5
Supplements: Fish oil (including cod liver oil)	0.2	0.2	0.7	-0.5	0.4	-0.4	0.5	-0.2	-0.6	-0.3	-0.2	0.6	0.5	-0.8	0.1	0.2	-0.1	0.6	0.6	-0.2	-0.4	-0.3	-0.6	-0.2	-0.6	-0.4
Ever smoked	0.2	0.4	2.2	0.1	0.7	0.7	0.9	-0.4	0.8	-0.2	0.6	0.7	1.5	0.3	0.1	0.5	0.8	0.6	-0.3	-0.6	-0.3	0.3	0.3	-0.4	-0.0	-0.1
Ever depressed for a whole week	0.2	0.3	0.8	-0.5	-0.8	-0.6	-0.3	-0.6	0.5	-0.3	-0.5	0.0	0.0	0.6	0.4	0.2	0.4	-0.4	-0.5	-0.9	-0.4	-0.6	-0.3	-0.5	-0.7	-0.9
Sitting height	0.1	0.6	6.1	-0.0	2.5	0.7	-0.7	-0.1	0.7	-0.7	-0.2	1.4	0.3	0.5	0.4	0.1	1.2	0.8	-0.0	0.2	-0.7	0.4	0.2	0.5	0.0	0.0
Qualifications: A levels/AS levels or equivalent	0.1	0.3	2.1	-0.4	-1.4	0.6	-0.3	-0.5	-0.8	-0.4	-0.6	0.2	-0.1	0.8	0.3	0.1	0.4	-0.0	0.2	-0.3	-0.6	-0.3	-0.5	0.3	-0.5	-0.3
Neck or shoulder pain in last month	0.1	0.2	1.1	0.3	0.7	0.2	0.1	0.0	-0.0	0.0	0.2	0.7	0.7	0.2	1.1	-0.2	0.6	0.2	0.7	0.1	0.1	-0.1	-0.1	0.4	-0.2	-0.5
Hair Pigment	0.0	0.8	5.7	-0.4	1.8	1.4	2.4	0.0	0.7	-0.6	0.6	1.2	1.1	-0.3	-0.0	-0.0	1.0	0.7	-0.7	-0.5	-0.7	0.2	-0.2	-0.0	-0.1	-0.8

Hub : Genes

TMEM9B

Models

Trait associations